Susanna Brighenti

About me
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About me

Immunologist with a research focus on tuberculosis (TB) infection and disease who has a large interest in basic and clinical research.

Research

My group study immunopathogenesis in TB and how immune responses that are suppressed by M. tuberculosis can be restored to support antibiotic treatment and prevent the mergence of antimicrobial resistance.

Teaching

Extensive experience of teaching and education including supervision of PhD students at Karolinska Institutet.

Articles

Article: IMMUNOBIOLOGY. 2023;228(2):152350

Immune cell landscape in symptomatic and asymptomatic SARS-CoV-2 infected adults and children in urban Dhaka, Bangladesh.

Akhtar E; Mily A; Sarker P; Chanda BC; Haque F; Kuddusi RU; Haq MA; Lourda M; Brighenti S; Raqib R
Article: RESPIRATORY RESEARCH. 2023;24(1):62

Targeted plasma proteomics reveals signatures discriminating COVID-19 from sepsis with pneumonia.

Palma Medina LM; Babačić H; Dzidic M; Parke Å; Garcia M; Maleki KT; Unge C; Lourda M; Kvedaraite E; Chen P; Muvva JR; Cornillet M; Emgård J; Moll K; Karolinska K. I./K. COVID-19 Study Group; Michaëlsson J; Flodström-Tullberg M; Brighenti S; Buggert M; Mjösberg J; Malmberg K-J; Sandberg JK; Gredmark-Russ S; Rooyackers O; Svensson M; Chambers BJ; Eriksson LI; Pernemalm M; Björkström NK; Aleman S; Ljunggren H-G; Klingström J; Strålin K; Norrby-Teglund A
Journal article: FRONTIERS IN IMMUNOLOGY. 2023;14:1296501

Inflammatory immune profiles associated with disease severity in pulmonary tuberculosis patients with moderate to severe clinical TB or anemia.

Ashenafi S; Loreti MG; Bekele A; Aseffa G; Amogne W; Kassa E; Aderaye G; Brighenti S
Article: MBIO. 2022;13(5):e0108622-e01022

High Glucose and Carbonyl Stress Impair HIF-1-Regulated Responses and the Control of Mycobacterium tuberculosis in Macrophages.

Terán G; Li H; Catrina S-B; Liu R; Brighenti S; Zheng X; Grünler J; Nylén S; Carow B; Rottenberg ME
Article: NUTRIENTS. 2022;14(16):3318

Anemia Is a Strong Predictor of Wasting, Disease Severity, and Progression, in Clinical Tuberculosis (TB).

Ashenafi S; Bekele A; Aseffa G; Amogne W; Kassa E; Aderaye G; Worku A; Bergman P; Brighenti S
Article: AMERICAN JOURNAL OF PATHOLOGY. 2022;192(4):653-670

Immunosuppressive Features of the Microenvironment in Lymph Nodes Granulomas from Tuberculosis and HIV-Co-Infected Patients.

Ashenafi S; Muvva JR; Mily A; Snäll J; Zewdie M; Chanyalew M; Rehn A; Rahman S; Aseffa G; Bekele A; Aderaye G; Lema B; Svensson M; Brighenti S
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2021;118(40):e2109123118

High-dimensional profiling reveals phenotypic heterogeneity and disease-specific alterations of granulocytes in COVID-19.

Lourda M; Dzidic M; Hertwig L; Bergsten H; Palma Medina LM; Sinha I; Kvedaraite E; Chen P; Muvva JR; Gorin J-B; Cornillet M; Emgård J; Moll K; García M; Maleki KT; Klingström J; Michaëlsson J; Flodström-Tullberg M; Brighenti S; Buggert M; Mjösberg J; Malmberg K-J; Sandberg JK; Henter J-I; Folkesson E; Gredmark-Russ S; Sönnerborg A; Eriksson LI; Rooyackers O; Aleman S; Strålin K; Ljunggren H-G; Björkström NK; Svensson M; Ponzetta A; Norrby-Teglund A; Chambers BJ; Karolinska KI/K COVID-19 Study Group
Article: JOURNAL OF INFECTIOUS DISEASES. 2021;224(2):332-344

Immunomodulatory Agents Combat Multidrug-Resistant Tuberculosis by Improving Antimicrobial Immunity.

Rao Muvva J; Ahmed S; Rekha RS; Kalsum S; Groenheit R; Schön T; Agerberth B; Bergman P; Brighenti S
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2021;118(6):e2018587118

Major alterations in the mononuclear phagocyte landscape associated with COVID-19 severity.

Kvedaraite E; Hertwig L; Sinha I; Ponzetta A; Hed Myrberg I; Lourda M; Dzidic M; Akber M; Klingström J; Folkesson E; Muvva JR; Chen P; Gredmark-Russ S; Brighenti S; Norrby-Teglund A; Eriksson LI; Rooyackers O; Aleman S; Strålin K; Ljunggren H-G; Ginhoux F; Björkström NK; Henter J-I; Svensson M; Karolinska KI/K COVID-19 Study Group
Article: CLINICAL & TRANSLATIONAL IMMUNOLOGY. 2021;10(7):e1306

SARS-CoV-2-specific humoral and cellular immunity persists through 9 months irrespective of COVID-19 severity at hospitalisation.

Sandberg JT; Varnaitė R; Christ W; Chen P; Muvva JR; Maleki KT; García M; Dzidic M; Folkesson E; Skagerberg M; Ahlén G; Frelin L; Sällberg M; Eriksson LI; Rooyackers O; Sönnerborg A; Buggert M; Björkström NK; Aleman S; Strålin K; Klingström J; Ljunggren H-G; Blom K; Gredmark-Russ S; Karolinska COVID‐19 Study Group
Article: BMC INFECTIOUS DISEASES. 2020;20(1):933

Slow radiological improvement and persistent low-grade inflammation after chemotherapy in tuberculosis patients with type 2 diabetes.

Mily A; Sarker P; Taznin I; Hossain D; Haq MA; Kamal SMM; Agerberth B; Brighenti S; Raqib R
Article: CELL. 2020;183(1):158-168.e14

Robust T Cell Immunity in Convalescent Individuals with Asymptomatic or Mild COVID-19.

Sekine T; Perez-Potti A; Rivera-Ballesteros O; Strålin K; Gorin J-B; Olsson A; Llewellyn-Lacey S; Kamal H; Bogdanovic G; Muschiol S; Wullimann DJ; Kammann T; Emgård J; Parrot T; Folkesson E; Karolinska COVID-19 Study Group; Rooyackers O; Eriksson LI; Henter J-I; Sönnerborg A; Allander T; Albert J; Nielsen M; Klingström J; Gredmark-Russ S; Björkström NK; Sandberg JK; Price DA; Ljunggren H-G; Aleman S; Buggert M
Article: SCIENCE IMMUNOLOGY. 2020;5(51):eabe1670

MAIT cell activation and dynamics associated with COVID-19 disease severity.

Parrot T; Gorin J-B; Ponzetta A; Maleki KT; Kammann T; Emgård J; Perez-Potti A; Sekine T; Rivera-Ballesteros O; Karolinska COVID-19 Study Group; Gredmark-Russ S; Rooyackers O; Folkesson E; Eriksson LI; Norrby-Teglund A; Ljunggren H-G; Björkström NK; Aleman S; Buggert M; Klingström J; Strålin K; Sandberg JK
Journal article: JOVE-JOURNAL OF VISUALIZED EXPERIMENTS. 2020;(163)

Polarization of M1 and M2 Human Monocyte-Derived Cells and Analysis with Flow Cytometry upon Mycobacterium tuberculosis Infection

Mily A; Kalsum S; Loreti MG; Rekha RS; Muvva JR; Lourda M; Brighenti S
Article: JOVE-JOURNAL OF VISUALIZED EXPERIMENTS. 2020;(163)

Polarization of M1 and M2 Human Monocyte-Derived Cells and Analysis with Flow Cytometry upon Mycobacterium tuberculosis Infection.

Mily A; Kalsum S; Loreti MG; Rekha RS; Muvva JR; Lourda M; Brighenti S
Article: SCIENCE IMMUNOLOGY. 2020;5(50):eabd6832

Natural killer cell immunotypes related to COVID-19 disease severity.

Maucourant C; Filipovic I; Ponzetta A; Aleman S; Cornillet M; Hertwig L; Strunz B; Lentini A; Reinius B; Brownlie D; Cuapio A; Ask EH; Hull RM; Haroun-Izquierdo A; Schaffer M; Klingström J; Folkesson E; Buggert M; Sandberg JK; Eriksson LI; Rooyackers O; Ljunggren H-G; Malmberg K-J; Michaëlsson J; Marquardt N; Hammer Q; Strålin K; Björkström NK; Karolinska COVID-19 Study Group
Article: NUTRIENTS. 2019;11(7):E1675-1675

Vitamin D and Phenylbutyrate Supplementation Does Not Modulate Gut Derived Immune Activation in HIV-1.

Missailidis C; Sørensen N; Ashenafi S; Amogne W; Kassa E; Bekele A; Getachew M; Gebreselassie N; Aseffa A; Aderaye G; Andersson J; Brighenti S; Bergman P
Article: NUTRIENTS. 2019;11(1):E133-133

Daily Nutritional Supplementation with Vitamin D₃ and Phenylbutyrate to Treatment-Naïve HIV Patients Tested in a Randomized Placebo-Controlled Trial.

Ashenafi S; Amogne W; Kassa E; Gebreselassie N; Bekele A; Aseffa G; Getachew M; Aseffa A; Worku A; Hammar U; Bergman P; Aderaye G; Andersson J; Brighenti S
Article: FRONTIERS IN IMMUNOLOGY. 2019;10:3157

Polarization of Human Monocyte-Derived Cells With Vitamin D Promotes Control of Mycobacterium tuberculosis Infection.

Rao Muvva J; Parasa VR; Lerm M; Svensson M; Brighenti S
Article: JOURNAL OF INTERNAL MEDICINE. 2018;284(3):292-306

Daily adjunctive therapy with vitamin D3 and phenylbutyrate supports clinical recovery from pulmonary tuberculosis: a randomized controlled trial in Ethiopia.

Bekele A; Gebreselassie N; Ashenafi S; Kassa E; Aseffa G; Amogne W; Getachew M; Aseffa A; Worku A; Raqib R; Agerberth B; Hammar U; Bergman P; Aderaye G; Andersson J; Brighenti S
Article: NUTRIENTS. 2018;10(6):E721-721

Vitamin D₃ Status and the Association with Human Cathelicidin Expression in Patients with Different Clinical Forms of Active Tuberculosis.

Ashenafi S; Mazurek J; Rehn A; Lemma B; Aderaye G; Bekele A; Assefa G; Chanyalew M; Aseffa A; Andersson J; Bergman P; Brighenti S
Article: FASEB JOURNAL. 2018;32(5):2827-2840

Prostaglandin E2 suppresses hCAP18/LL-37 expression in human macrophages via EP2/EP4: implications for treatment of Mycobacterium tuberculosis infection.

Wan M; Tang X; Rekha RS; Muvva SSVJR; Brighenti S; Agerberth B; Haeggström JZ
Article: RESPIRATORY MEDICINE. 2018;138S:S38-S44

Enhanced CD8+ cytolytic T cell responses in the peripheral circulation of patients with sarcoidosis and non-Löfgren's disease.

Parasa VR; Forsslund H; Enger T; Lorenz D; Kullberg S; Eklund A; Sköld M; Wahlström J; Grunewald J; Brighenti S
Article: INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES. 2017;59:29-36

IL-7δ5 protein is expressed in human tissues and induces expression of the oxidized low density lipoprotein receptor 1 (OLR1) in CD14+ monocytes.

Rane L; Rahman S; Magalhaes I; Ambati A; Andersson J; Zumla A; Brighenti S; Maeurer MJ
Article: VACCINE. 2017;35(12):1652-1661

Safety and immunogenicity of the novel H4:IC31 tuberculosis vaccine candidate in BCG-vaccinated adults: Two phase I dose escalation trials.

Norrby M; Vesikari T; Lindqvist L; Maeurer M; Ahmed R; Mahdavifar S; Bennett S; McClain JB; Shepherd BM; Li D; Hokey DA; Kromann I; Hoff ST; Andersen P; de Visser AW; Joosten SA; Ottenhoff THM; Andersson J; Brighenti S
Article: FRONTIERS IN MICROBIOLOGY. 2017;8:2370

Inhibition of Tissue Matrix Metalloproteinases Interferes with Mycobacterium tuberculosis-Induced Granuloma Formation and Reduces Bacterial Load in a Human Lung Tissue Model.

Parasa VR; Muvva JR; Rose JF; Braian C; Brighenti S; Lerm M
Article: MICROBIOLOGY SPECTRUM. 2016;4(6)

Regulation of Immunity to Tuberculosis.

Brighenti S; Ordway DJ
Article: ETHIOPIAN MEDICAL JOURNAL. 2016;54(4):181-188

LATENT TUBERCULOSIS AMONG ADULT ETHIOPIAN PATIENTS AT CHEST CLINIC, TIKURANBESSA SPECIALIZED HOSPITAL, ADDIS ABABA, ETHIOPIA.

Bekele A; Ashenafi S; Aderay G; Assefa G; Aseffa A; Anderssen J; Brighenti S
Article: CLINICAL INFECTIOUS DISEASES. 2015;61Suppl 3(Suppl 3):S225-S234

B in TB: B Cells as Mediators of Clinically Relevant Immune Responses in Tuberculosis.

Rao M; Valentini D; Poiret T; Dodoo E; Parida S; Zumla A; Brighenti S; Maeurer M
Article: JOVE-JOURNAL OF VISUALIZED EXPERIMENTS. 2015;(104):53084

A 3D Human Lung Tissue Model for Functional Studies on Mycobacterium tuberculosis Infection.

Braian C; Svensson M; Brighenti S; Lerm M; Parasa VR
Article: AUTOPHAGY. 2015;11(9):1688-1699

Phenylbutyrate induces LL-37-dependent autophagy and intracellular killing of Mycobacterium tuberculosis in human macrophages.

Rekha RS; Rao Muvva SSVJ; Wan M; Raqib R; Bergman P; Brighenti S; Gudmundsson GH; Agerberth B
Article: CLINICAL IMMUNOLOGY. 2015;156(2):85-97

Pulmonary tuberculosis patients with a vitamin D deficiency demonstrate low local expression of the antimicrobial peptide LL-37 but enhanced FoxP3+ regulatory T cells and IgG-secreting cells.

Rahman S; Rehn A; Rahman J; Andersson J; Svensson M; Brighenti S
Article: PLOS ONE. 2015;10(9):e0138340

Significant Effects of Oral Phenylbutyrate and Vitamin D3 Adjunctive Therapy in Pulmonary Tuberculosis: A Randomized Controlled Trial.

Mily A; Rekha RS; Kamal SMM; Arifuzzaman ASM; Rahim Z; Khan L; Haq MA; Zaman K; Bergman P; Brighenti S; Gudmundsson GH; Agerberth B; Raqib R
Article: CLINICAL IMMUNOLOGY. 2014;151(2):84-99

Progression of clinical tuberculosis is associated with a Th2 immune response signature in combination with elevated levels of SOCS3.

Ashenafi S; Aderaye G; Bekele A; Zewdie M; Aseffa G; Hoang ATN; Carow B; Habtamu M; Wijkander M; Rottenberg M; Aseffa A; Andersson J; Svensson M; Brighenti S
Article: DISEASE MODELS & MECHANISMS. 2014;7(2):281-288

Modeling Mycobacterium tuberculosis early granuloma formation in experimental human lung tissue.

Parasa VR; Rahman MJ; Ngyuen Hoang AT; Svensson M; Brighenti S; Lerm M
Article: THORAX. 2013;68(3):269-276

BCG-specific IgG-secreting peripheral plasmablasts as a potential biomarker of active tuberculosis in HIV negative and HIV positive patients.

Ashenafi S; Aderaye G; Zewdie M; Raqib R; Bekele A; Magalhaes I; Lema B; Habtamu M; Rekha RS; Aseffa G; Maeurer M; Aseffa A; Svensson M; Andersson J; Brighenti S
Article: JOURNAL OF INFECTIOUS DISEASES. 2012;205 Suppl 2:S316-S324

Local immune responses in human tuberculosis: learning from the site of infection.

Brighenti S; Andersson J
Article: MOLECULAR MEDICINE. 2012;18(1):647-658

Prime-boost vaccination with rBCG/rAd35 enhances CD8⁺ cytolytic T-cell responses in lesions from Mycobacterium tuberculosis-infected primates.

Rahman S; Magalhaes I; Rahman J; Ahmed RK; Sizemore DR; Scanga CA; Weichold F; Verreck F; Kondova I; Sadoff J; Thorstensson R; Spångberg M; Svensson M; Andersson J; Maeurer M; Brighenti S
Article: JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2012;132(1):114-123

Plasmacytoid dendritic cells infiltrate the skin in positive tuberculin skin test indurations.

Bond E; Liang F; Sandgren KJ; Smed-Sörensen A; Bergman P; Brighenti S; Adams WC; Betemariam SA; Rangaka MX; Lange C; Wilkinson RJ; Andersson J; Loré K
Article: GENES AND IMMUNITY. 2011;12(7):513-522

Increased (6 exon) interleukin-7 production after M. tuberculosis infection and soluble interleukin-7 receptor expression in lung tissue.

Rane L; Rahman S; Magalhaes I; Ahmed R; Spångberg M; Kondova I; Verreck F; Andersson J; Brighenti S; Maeurer MJ
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2010;396(1):50-57

Induction and regulation of CD8+ cytolytic T cells in human tuberculosis and HIV infection.

Brighenti S; Andersson J
Article: AMERICAN JOURNAL OF PATHOLOGY. 2009;174(6):2211-2224

Compartmentalization of immune responses in human tuberculosis: few CD8+ effector T cells but elevated levels of FoxP3+ regulatory t cells in the granulomatous lesions.

Rahman S; Gudetta B; Fink J; Granath A; Ashenafi S; Aseffa A; Derbew M; Svensson M; Andersson J; Brighenti SG
Article: INFECTION AND IMMUNITY. 2007;75(11):5210-5222

Impaired expression of perforin and granulysin in CD8+ T cells at the site of infection in human chronic pulmonary tuberculosis.

Andersson J; Samarina A; Fink J; Rahman S; Grundström S
Article: MICROBES AND INFECTION. 2006;8(8):1985-1993

Enhanced susceptibility of multidrug resistant strains of Mycobacterium tuberculosis to granulysin peptides correlates with a reduced fitness phenotype.

Toro JC; Hoffner S; Linde C; Andersson M; Andersson J; Grundström S
Article: INFECTION AND IMMUNITY. 2005;73(10):6332-6339

Conserved structure and function in the granulysin and NK-lysin peptide family.

Linde CMA; Grundström S; Nordling E; Refai E; Brennan PJ; Andersson M
Article: JOURNAL OF IMMUNOLOGICAL METHODS. 2005;302(1-2):13-25

Detection of human perforin by ELISpot and ELISA: ex vivo identification of virus-specific cells.

Zuber B; Levitsky V; Jönsson G; Paulie S; Samarina A; Grundström S; Metkar S; Norell H; Callender GG; Froelich C; Ahlborg N
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2004;279(9):8460-8468

Bcl-3 and NFkappaB p50-p50 homodimers act as transcriptional repressors in tolerant CD4+ T cells.

Grundström S; Anderson P; Scheipers P; Sundstedt A
Article: JOURNAL OF IMMUNOLOGY. 2003;170(10):5008-5017

Superantigen-induced regulatory T cells display different suppressive functions in the presence or absence of natural CD4+CD25+ regulatory T cells in vivo.

Grundström S; Cederbom L; Sundstedt A; Scheipers P; Ivars F
Article: JOURNAL OF IMMUNOLOGY. 2000;164(3):1175-1184

IL-2 unresponsiveness in anergic CD4+ T cells is due to defective signaling through the common gamma-chain of the IL-2 receptor.

Grundström S; Dohlsten M; Sundstedt A
Article: IMMUNOLOGY. 1998;95(1):76-82

T cell- and perforin-dependent depletion of B cells in vivo by staphylococcal enterotoxin A.

Sundstedt A; Grundström S; Dohlsten M
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All other publications

Review: FRONTIERS IN IMMUNOLOGY. 2022;13:1059725

Reinventing the human tuberculosis (TB) granuloma: Learning from the cancer field.

Ashenafi S; Brighenti S
Corrigendum: JOVE-JOURNAL OF VISUALIZED EXPERIMENTS. 2020;(164)

Erratum: Polarization of M1 and M2 Human Monocyte-Derived Cells and Analysis with Flow Cytometry upon Mycobacterium tuberculosis Infection.
Editorial comment: NUTRIENTS. 2020;12(6):E1682-1682

Targeted Nutrition in Chronic Disease.

Bergman P; Brighenti S
Review: FRONTIERS IN MEDICINE. 2020;7:537

Host and Pathogen Communication in the Respiratory Tract: Mechanisms and Models of a Complex Signaling Microenvironment.

Berry SB; Haack AJ; Theberge AB; Brighenti S; Svensson M
Editorial comment: JOURNAL OF INTERNAL MEDICINE. 2018;:113-115

Toward the understanding of human tuberculosis.

Brighenti S; Lerm M
Review: JOURNAL OF INTERNAL MEDICINE. 2018;:163-188

Perspectives for personalized therapy for patients with multidrug-resistant tuberculosis.

Lange C; Alghamdi WA; Al-Shaer MH; Brighenti S; Diacon AH; DiNardo AR; Grobbel HP; Gröschel MI; von Groote-Bidlingmaier F; Hauptmann M; Heyckendorf J; Köhler N; Kohl TA; Merker M; Niemann S; Peloquin CA; Reimann M; Schaible UE; Schaub D; Schleusener V; Thye T; Schön T
Review: JOURNAL OF INTERNAL MEDICINE. 2018;:145-162

Vitamin D and tuberculosis: where next?

Brighenti S; Bergman P; Martineau AR
Review: JOURNAL OF INTERNAL MEDICINE. 2018;:125-144

Friends and foes of tuberculosis: modulation of protective immunity.

Brighenti S; Joosten SA
Book chapter: TUBERCULOSIS AND THE TUBERCLE BACILLUS. 2017;p. 73-93

Regulation of Immunity to Tuberculosis

Brighenti S; Ordway DJ
Review: INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES. 2017;56:140-154

Peptide microarray-based characterization of antibody responses to host proteins after bacille Calmette-Guérin vaccination.

Valentini D; Rao M; Rane L; Rahman S; Axelsson-Robertson R; Heuchel R; Löhr M; Hoft D; Brighenti S; Zumla A; Maeurer M
Review: INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES. 2017;56:167-175

Humoral immune profiling of mycobacterial antigen recognition in sarcoidosis and Löfgren's syndrome using high-content peptide microarrays.

Ferrara G; Valentini D; Rao M; Wahlström J; Grunewald J; Larsson L-O; Brighenti S; Dodoo E; Zumla A; Maeurer M
Letter: THORAX. 2011;66(8):727-729

A new potential biomarker for childhood tuberculosis.

Thomas T; Brighenti S; Andersson J; Sack D; Raqib R
Review: CURRENT HIV/AIDS REPORTS. 2006;3(1):32-38

Studies of HIV-associated immune responses in lymphoid compartments.

Grundström S; Andersson J

Grants

Immune profiling and immune checkpoint modulation of multidrug-resistant tuberculosis infection (IPIM)

Swedish Research Council

1 January 2023 - 31 December 2026
Discovery of epigenetic modulators designed to treat and cure different tuberculosis endotypes by improving antimicrobial cellular immunity

Swedish Research Council

1 December 2022 - 30 November 2025
Towards two-step combination treatment with epigenetic- and immune-modulating drugs to promote cure and prevent antibiotic resistance in tuberculosis

Swedish Research Council

1 January 2020 - 31 December 2022
Exploring epigenetic alterations of cellular immunity in multidrug-resistant tuberculosis with relevance for new therapy using epigenetic- and immune-modulating drugs

Swedish Research Council

1 January 2020 - 31 December 2022
Mot två-stegs kombinationsbehandling med preparat som har epigenetiska- och immunmodulerande egenskaper som kan stödja utläkning av samt förhindra utveckling av antibiotika resistent tuberkulos

Swedish Heart-Lung Foundation

1 January 2020 - 31 December 2022
Mot två-stegs kombinationsbehandling med preparat som har epigenetiska- och immunmodulerandeegenskaper som kan stödja utläkning av samt förhindra utveckling av antibiotika resistent tuberkulos

Swedish Heart-Lung Foundation

1 January 2020 - 31 December 2022
10th International Conference on the Pathogenesis of Mycobacterial Infections

Swedish Research Council

1 November 2016 - 30 November 2016
An innovative human lung tissue model for tuberculosis research

Swedish Research Council

1 January 2015 - 31 December 2017
Discovery of immunopathogenesis in human tuberculosis: new concepts for diagnosis and treatment

Swedish Research Council

1 January 2015 - 31 December 2017
The role of diabetes-associated pathology in the development of clinical tuberculosis: a collaborative project between Sweden and Bangladesh

Swedish Research Council

1 January 2015 - 31 December 2018
Innovative human lung tissue model for tuberculosis research

Swedish Research Council

1 January 2013 - 31 December 2014
Novel treatment of infectious diseases via induction of mucosal immunity

Swedish Research Council

1 January 2013 - 31 December 2015
Discovery of pathogenesis in human tuberculosis with novel implications for clinical practise

Swedish Research Council

1 January 2012 - 31 December 2014
8th International Conference on the Pathogenesis of Mycobacterial Infections

Swedish Research Council

1 July 2010 - 31 December 2010
Studies of dysfunctional immunity in HIV disease with implications for immune reconstitution and vaccine development

Swedish Research Council

1 January 2010 - 31 December 2012

Employments

Principal Researcher, Immunology of tuberculosis (TB), Department of Medicine, Huddinge, Karolinska Institutet, 2014-

Degrees and Education

Docent, Karolinska Institutet, 2014

About me

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