Stefan Spulber

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Articles

Article: BRAIN, BEHAVIOR, AND IMMUNITY. 2025;123:28-42
Bi-allelic NRXN1α deletion in microglia derived from iPSC of an autistic patient increases interleukin-6 production and impairs supporting function on neuronal networking
Bose R; Posada-Perez M; Karvela E; Skandik M; Keane L; Falk A; Spulber S; Joseph B; Ceccatelli S
Journal article: FRONTIERS IN TOXICOLOGY. 2024;6:1397477
Decreased activity in zebrafish larvae exposed to glyphosate-based herbicides during development-potential mediation by glucocorticoid receptor
Spulber S; Reis L; Alexe P; Ceccatelli S
Article: MOLECULAR NEUROBIOLOGY. 2023;60(12):7346-7361
Sex Differences in Long-term Outcome of Prenatal Exposure to Excess Glucocorticoids-Implications for Development of Psychiatric Disorders
Elberling F; Spulber S; Bose R; Keung HY; Ahola V; Zheng Z; Ceccatelli S
Article: TRANSLATIONAL PSYCHIATRY. 2022;12(1):226
Patterns of activity correlate with symptom severity in major depressive disorder patients
Spulber S; Elberling F; Svensson J; Tiger M; Ceccatelli S; Lundberg J
Article: NEUROTOXICOLOGY. 2021;83:1-13
In utero exposure to dexamethasone causes a persistent and age-dependent exacerbation of the neurotoxic effects and glia activation induced by MDMA in dopaminergic brain regions of C57BL/6J mice
Costa G; Spulber S; Paci E; Casu MA; Ceccatelli S; Simola N; Morelli M
Article: JOURNAL OF CLINICAL SLEEP MEDICINE. 2020;16(9):1567-1577
A randomized controlled study of weighted chain blankets for insomnia in psychiatric disorders
Ekholm B; Spulber S; Adler M
Article: TRANSLATIONAL PSYCHIATRY. 2019;9(1):263
Desipramine restores the alterations in circadian entrainment induced by prenatal exposure to glucocorticoids
Spulber S; Conti M; Elberling F; Raciti M; Borroto-Escuela DO; Fuxe K; Ceccatelli S
Article: JOURNAL OF NEUROSCIENCE METHODS. 2019;311:259-266
Spinal cord injury in zebrafish induced by near-infrared femtosecond laser pulses
Ellstrom ID; Spulber S; Hultin S; Norlin N; Ceccatelli S; Hultling C; Uhlen P
Article: FRONTIERS IN GENETICS. 2019;10:593
NRXN1 Deletion and Exposure to Methylmercury Increase Astrocyte Differentiation by Different Notch-Dependent Transcriptional Mechanisms
Raciti M; Selma J; Spulber S; Gaudenzi G; Khalajzeyqami Z; Conti M; Anderlid B-M; Falk A; Hermanson O; Ceccatelli S
Article: TOXICOLOGY AND APPLIED PHARMACOLOGY. 2018;354:94-100
Methylmercury interferes with glucocorticoid receptor: Potential role in the mediation of developmental neurotoxicity
Spulber S; Raciti M; Dulko-Smith B; Lupu D; Ruegg J; Nam K; Ceccatelli S
Article: NEUROPHARMACOLOGY. 2017;126:242-249
Depressive-like phenotype induced by prenatal dexamethasone in mice is reversed by desipramine
Conti M; Spulber S; Raciti M; Ceccatelli S
Article: TOXICOLOGY AND APPLIED PHARMACOLOGY. 2016;301:14-21
Effects of developmental exposure to perfluorooctanoic acid (PFOA) on long bone morphology and bone cell differentiation
Koskela A; Finnila MA; Korkalainen M; Spulber S; Koponen J; Hakansson H; Tuukkanen J; Viluksela M
Article: TRANSLATIONAL PSYCHIATRY. 2015;5(7):e603
Alterations in circadian entrainment precede the onset of depression-like behavior that does not respond to fluoxetine
Spulber S; Conti M; DuPont C; Raciti M; Bose R; Onishchenko N; Ceccatelli S
Article: CELL DEATH AND DISEASE. 2015;6(6):e1793
Tet3 mediates stable glucocorticoid-induced alterations in DNA methylation and Dnmt3a/Dkk1 expression in neural progenitors
Bose R; Spulber S; Kilian P; Heldring N; Lonnerberg P; Johnsson A; Conti M; Hermanson O; Ceccatelli S
Article: PLOS ONE. 2014;9(4):e94227
PFOS Induces Behavioral Alterations, Including Spontaneous Hyperactivity That Is Corrected by Dexamfetamine in Zebrafish Larvae
Spulber S; Kilian P; Ibrahim WNW; Onishchenko N; Ulhaq M; Norrgren L; Negri S; Di Tuccio M; Ceccatelli S
Article: JOURNAL OF THE NEUROLOGICAL SCIENCES. 2012;322(1-2):184-186
Claudin expression profile separates Alzheimer's disease cases from normal aging and from vascular dementia cases
Spulber S; Bogdanovic N; Romanitan MO; Bajenaru OA; Popescu BO
Article: JOURNAL OF CELLULAR AND MOLECULAR MEDICINE. 2012;16(6):1223-1231
Apoptosis in seborrheic keratoses: an open door to a new dermoscopic score
Simionescu O; Popescu BO; Costache M; Manole E; Spulber S; Gherghiceanu M; Blum A
Article: PLOS ONE. 2012;7(7):e42078
Molecular Hydrogen Reduces LPS-Induced Neuroinflammation and Promotes Recovery from Sickness Behaviour in Mice
Spulber S; Edoff K; Hong L; Morisawa S; Shirahata S; Ceccatelli S
Article: NEUROTOXICITY RESEARCH. 2011;19(3):452-461
Prenatal Exposure to PFOS or PFOA Alters Motor Function in Mice in a Sex-Related Manner
Onishchenko N; Fischer C; Ibrahim WNW; Negri S; Spulber S; Cottica D; Ceccatelli S
Article: JOURNAL OF NEUROSCIENCE RESEARCH. 2011;89(2):142-152
Morphological and Behavioral Changes Induced by Transgenic Overexpression of Interleukin-1ra in the Brain
Spulber S; Bartfai T; Winblad B; Schultzberg M
Article: TOXICOLOGICAL SCIENCES. 2010;117(2):263-269
Effects of Maternal Smoking and Exposure to Methylmercury on Brain-Derived Neurotrophic Factor Concentrations in Umbilical Cord Serum
Spulber S; Rantamaki T; Nikkila O; Castren E; Weihe P; Grandjean P; Ceccatelli S
Article: JOURNAL OF CELLULAR AND MOLECULAR MEDICINE. 2010;14(5):1088-1100
Altered expression of claudin family proteins in Alzheimer's disease and vascular dementia brains
Romanitan MO; Popescu BO; Spulber S; Bajenaru O; Popescu LM; Winblad B; Bogdanovic N
Article: JOURNAL OF NEUROIMMUNOLOGY. 2009;208(1-2):46-53
Impaired long term memory consolidation in transgenic mice overexpressing the human soluble form of IL-1ra in the brain
Spulber S; Mateos L; Oprica M; Cedazo-Minguez A; Bartfai T; Winblad B; Schultzberg M
Article: EPILEPSIA. 2009;50(2):297-303
Growth dependence on insulin-like growth factor-1 during the ketogenic diet
Spulber G; Spulber S; Hagenas L; Amark P; Dahlin M
Article: BRAIN PATHOLOGY. 2009;19(1):69-80
Activity-Regulated Cytoskeleton-Associated Protein in Rodent Brain is Down-Regulated by High Fat Diet in vivo and by 27-Hydroxycholesterol in vitro
Mateos L; Akterin S; Gil-Bea F-J; Spulber S; Rahman A; Bjorkhem I; Schultzberg M; Flores-Morales A; Cedazo-Minguez A
Journal article: ALZHEIMER'S AND DEMENTIA. 2008;4(4S_Part_7):t239
P1‐111: Transgenic block of Il‐1 receptor‐mediated signalling results in impaired learning
Spulber S; Oprica M; Winblad B; Schultzberg M
Journal article: ALZHEIMER'S AND DEMENTIA. 2008;4(4S_Part_20):t643
P3‐414: Activity‐regulated cytoskeleton‐associated protein in rodent brain is down‐regulated by high fat diet in vivo and by 27‐hydroxycholesterol in vitro
Mateos L; Akterin S; Gil-Bea F-J; Spulber S; Rahman A; Björkhem I; Schultzberg M; Flores-Morales A; Cedazo-Minguez A
Article: EUROPEAN JOURNAL OF NEUROSCIENCE. 2008;27(3):549-558
Blunted neurogenesis and gliosis due to transgenic overexpression of human soluble IL-1ra in the mouse
Spulber S; Oprica M; Bartfai T; Winblad B; Schultzberg M
Article: JOURNAL OF MOLECULAR NEUROSCIENCE. 2007;33(3):239-251
α-MSH rescues neurons from excitotoxic cell death
Asa FA; Stefan S; Mircea O; Bengt W; Claes P; Schultzberg M
Article: PHYSIOLOGY AND BEHAVIOR. 2007;92(1-2):121-128
Inflammation in the nervous system -: Physiological and pathophysiological aspects
Schultzberg M; Lindberg C; Aronsson AF; Hjorth E; Spulber SD; Oprica M
Article: JOURNAL OF CELLULAR AND MOLECULAR MEDICINE. 2007;11(4):810-825
Studies on brain volume, Alzheimer-related proteins and cytokines in mice with chronic overexpression of IL-1 receptor antagonist
Oprica M; Hjorth E; Spulber S; Popescu BO; Ankarcrona M; Winblad B; Schultzberg M
Article: CYTOKINE. 2006;35(1-2):77-87
The influence of kainic acid on core temperature and cytokine levels in the brain
Oprica M; Spulber SD; Aronsson AF; Post C; Winblad B; Schultzberg M
Journal article: ALZHEIMER'S AND DEMENTIA. 2006;2(3S_Part_4):s108
P1–048: Transgenic overexpression of IL–1ra decreases neurogenesis in young, but not in old mice
Spulber S; Oprica M; Winblad B; Schultzberg M
Article: EUROPEAN JOURNAL OF NEUROSCIENCE. 2006;23(8):2135-2144
Delayed ischemic electrocortical suppression during rapid repeated cerebral ischemia and kainate-induced seizures in rat
Ilie A; Spulber S; Avramescu S; Nita DA; Zagrean AM; Zagrean L; Moldovan M
Article: NEUROREPORT. 2005;16(1):69-72
α-MSH decreases core and brain temperature during global cerebral ischemia in rats
Spulber S; Moldovan M; Oprica M; Aronsson Å; Post C; Winblad B; Schultzberg M
Article: ROMANIAN JOURNAL OF PHYSIOLOGY : PHYSIOLOGICAL SCIENCES / [ACADEMIA DE STIINTE MEDICALE]. 2004;41(1-2):31-39
The relationship between respiratory sinus arrhythmia and heart rate during anesthesia in rat.
Moldovan M; Spulber S; Saravan V; Iosifescu R; Zăgrean A-M; Zăgrean L
Article: JOURNAL OF CELLULAR AND MOLECULAR MEDICINE. 2001;5(2):163-170
Oxidative damage following cerebral ischemia depends on reperfusion - a biochemical study in rat
Nita DA; Nita V; Spulber S; Moldovan M; Popa DP; Zagrean AM; Zagrean L
Article: JOURNAL OF CELLULAR AND MOLECULAR MEDICINE. 2000;4(3):215-223
Early electrocortical changes consistent with ischemic preconditioning in rat.
Zagrean L; Moldovan M; Munteanu A-M; Spulber S; Voiculescu BA; Popescu BO
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Corrigendum: NEUROTOXICOLOGY. 2024;101:128-130
In utero exposure to dexamethasone causes a persistent and age-dependent exacerbation of the neurotoxic effects and glia activation induced by MDMA in dopaminergic brain regions of C57BL/6J mice (vol 83, Pg 1, 2021)
Costa G; Spulber S; Paci E; Casu MA; Ceccatelli S; Simola N; Morelli M
Preprint: MEDRXIV. 2024
Individual patterns of activity predict the response to physical exercise as an intervention in mild to moderate depression
Spulber S; Ceccatelli S; Forsell Y
Corrigendum: NEUROTOXICOLOGY. 2023;:3136
Corrigendum to "In utero exposure to dexamethasone causes a persistent and age-dependent exacerbation of the neurotoxic effects and glia activation induced by MDMA in dopaminergic brain regions of C57BL/6J mice" NeuroToxicology 83 (2021) 1-13.
Costa G; Spulber S; Paci E; Antonietta Casu M; Ceccatelli S; Simola N; Morelli M
Preprint: MEDRXIV. 2023
Correlations between patterns of activity and the response to treatment yield distinct signatures for different antidepressive treatments
Spulber S; Elberling F; Ceccatelli S; Gärde M; Tiger M; Lundberg J
Review: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2023;24(5):4338
The Threat Posed by Environmental Contaminants on Neurodevelopment: What Can We Learn from Neural Stem Cells?
Bose R; Spulber S; Ceccatelli S
Preprint: BIORXIV. 2022
Early pre-neural serotonin modulates balance of late monoamines and behavioral patterns in fish model system
Ivashkin E; Spulber S; Zinovyev A; Yoshitake T; Yoshitake S; Kharchenko O; Khabarova MY; Theofilopoulos S; Kehr J; Arenas E; Ceccatelli S; Voronezhskaya EE; Adameyko I
Book chapter: HANDBOOK OF NEUROTOXICITY. 2022;p. 2435-2456
Methylmercury Exposure and Developmental Neurotoxicity: New Insights from Neural Stem Cells
Bose R; Spulber S; Ceccatelli S
Book chapter: HANDBOOK OF NEUROTOXICITY. 2021;p. 1-23
Methylmercury Exposure and Developmental Neurotoxicity: New Insights from Neural Stem Cells
Bose R; Spulber S; Ceccatelli S
Review: PROGRESS IN NEUROBIOLOGY. 2017;155:21-35
Long-term consequences of prenatal stress and neurotoxicants exposure on neurodevelopment
Antonelli MC; Eugenia Pallares M; Ceccatelli S; Spulber S
Review: JOURNAL OF INTERNAL MEDICINE. 2013;273(5):490-497
Long-lasting neurotoxic effects of exposure to methylmercury during development
Ceccatelli S; Bose R; Edoff K; Onishchenko N; Spulber S
Book chapter: METHYLMERCURY AND NEUROTOXICITY: CURRENT TOPICS IN NEUROTOXICITY. 2012;p. 163-198
Behavioural Effects of Exposure to Methylmercury During Early Development
Onishchenko N; Spulber S; Ceccatelli S
Conference publication: GLIA. 2011;59:S19
OVEREXPRESSION OF TIGHT JUNCTION PROTEINS IN GLIAL CELLS IN ALZHEIMER'S DISEASE AND VASCULAR DEMENTIA
Popescu BO; Romanitan MO; Spulber S; Bogdanovic N; Bajenaru O; Popescu LM
Published conference paper: PROGRESS IN NEUROBIOLOGY. 2010;90(2):256-262
Connection between inflammatory processes and transmittor function-Modulatory effects of interleukin-1
Spulber S; Schultzberg M
Review: BRAIN, BEHAVIOR, AND IMMUNITY. 2009;23(5):573-579
IL-1/IL-1ra balance in the brain revisited - Evidence from transgenic mouse models
Spulber S; Bartfai T; Schultzberg M
Thesis / dissertation: 2008
Blocking interleukin-1 signalling in the brain-structural and functional outcomes
Spulber, Stefan
Published conference paper: NEUROPEPTIDES. 2006;40(1):65-75
α-melanocyte-stimulating hormone is neuroprotective in rat global cerebral ischemia
Aronsson AF; Spulber S; Popescu LM; Winblad B; Post C; Oprica M; Schultzberg M
Conference publication: INTERNATIONAL PSYCHOGERIATRICS. 2005;17:133-134
Transgenic overexpression of interleukin-1 receptor antagonist in relation to brain morphology and the process of aging
Oprica M; Spulber S; Winblad B; Schultzberg M

Grants

Effects of hormones on neural cell fate: long-lasting consequences of adverse prenatal factors.
Swedish Research Council
1 January 2020 - 31 December 2023
EFFECTS OF HORMONES ON NEURAL CELL DEATH AND SURVIVAL: long-lasting consequences of adverse prenatal factors.
Swedish Research Council
1 January 2010 - 31 December 2012

Employments

Research Specialist, Department of Neuroscience, Karolinska Institutet, 2022-

Degrees and Education

Degree Of Doctor Of Philosophy, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, 2008

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