Sophie Curbo

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Articles

Article: JOURNAL OF EDUCATIONAL EVALUATION FOR HEALTH PROFESSIONS. 2023;20:13
Students' performance of and perspective on an objective structured practical examination for the assessment of preclinical and practical skills in biomedical laboratory science students in Sweden: a 5-year longitudinal study
Hultgren C; Lindkvist A; Curbo S; Heverin M
Article: JOURNAL OF EDUCATIONAL EVALUATION FOR HEALTH PROFESSIONS. 2023;20:32
ChatGPT (GPT-3.5) as an assistant tool in microbial pathogenesis studies in Sweden: a cross-sectional comparative study
Hultgren C; Lindkvist A; Ozenci V; Curbo S
Article: PLOS ONE. 2023;18(10):e0285242
Long term survival and abnormal liver fat accumulation in mice with specific thymidine kinase 2 deficiency in liver tissue
Zhao Q; Zhou X; Yan J; Kuiper R; Curbo S; Karlsson A
Article: JOURNAL OF IMMUNOLOGICAL METHODS. 2022;510:113347
Development of an ELISA displaying similar reactivity with reduced and oxidized human Thioredoxin-1 (Trx1): The plasma level of Trx1 in early onset psychosis disorders
Lundberg M; Bohman H; Curbo S; Mansouri S; Agartz I; Arestrom I; Ahlborg N
Article: PLOS ONE. 2022;17(6):e0270418
Mitochondria! dysfunction is associated with lipid metabolism disorder and upregulation of angiotensin-converting enzyme 2
Zhao Q; Zhou X; Kuiper R; Curbo S; Karlsson A
Article: HUMAN MOLECULAR GENETICS. 2021;30(21):2012-2026
Coordinated pyruvate kinase activity is crucial for metabolic adaptation and cell survival during mitochondrial dysfunction
Zhou X; Mikaeloff F; Curbo S; Zhao Q; Kuiper R; Vegvari A; Neogi U; Karlsson A
Article: BIOSCIENCE REPORTS. 2020;40(1):BSR20193156
Clozapine protects adult neural stem cells from ketamine-induced cell death in correlation with decreased apoptosis and autophagy
Lundberg M; Curbo S; Bohman H; Agartz I; Ogren S-O; Patrone C; Mansouri S
Article: HUMAN MOLECULAR GENETICS. 2019;28(17):2874-2884
Severe mtDNA depletion and dependency on catabolic lipid metabolism in DGUOK knockout mice
Zhou X; Curbo S; Zhao Q; Krishnan S; Kuiper R; Karlsson A
Article: SCIENTIFIC REPORTS. 2019;9(1):5656
Inhibition of the thioredoxin system by PX-12 (1-methylpropyl 2-imidazolyl disulfide) impedes HIV-1 infection in TZM-bl cells
Lundberg M; Mattsson A; Reiser K; Holmgren A; Curbo S
Article: BIOCHEMICAL PHARMACOLOGY. 2018;156:444-450
Metformin downregulates the mitochondrial carrier SLC25A10 in a glucose dependent manner
Zhao Q; Zhou X; Curbo S; Karlsson A
Article: BMC CANCER. 2018;18(1):559
Inhibition of glutamate oxaloacetate transaminase 1 in cancer cell lines results in altered metabolism with increased dependency of glucose
Zhou X; Curbo S; Li F; Krishnan S; Karlsson A
Article: PLOS ONE. 2016;11(1):e0147773
The Cellular Thioredoxin-1/Thioredoxin Reductase-1 Driven Oxidoreduction Represents a Chemotherapeutic Target for HIV-1 Entry Inhibition
Reiser K; Mathys L; Curbo S; Pannecouque C; Noppen S; Liekens S; Engman L; Lundberg M; Balzarini J; Karlsson A
Article: ONCOTARGET. 2015;6(11):9271-9283
The mitochondrial carrier SLC25A10 regulates cancer cell growth
Zhou X; Paredes JA; Krishnan S; Curbo S; Karlsson A
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2014;289(47):32835-32844
Long Term Expression of Drosophila melanogaster Nucleoside Kinase in Thymidine Kinase 2-deficient Mice with No Lethal Effects Caused by Nucleotide Pool Imbalances
Krishnan S; Paredes JA; Zhou X; Kuiper RV; Hultenby K; Curbo S; Karlsson A
Article: PLOS ONE. 2014;9(7):e103554
Methodological Aspects of ELISA Analysis of Thioredoxin 1 in Human Plasma and Cerebrospinal Fluid
Lundberg M; Curbo S; Reiser K; Masterman T; Braesch-Andersen S; Arestrom I; Ahlborg N
Article: ANTIOXIDANTS AND REDOX SIGNALING. 2013;18(7):795-799
Is Trichloroacetic Acid an Insufficient Sample Quencher of Redox Reactions?
Curbo S; Reiser K; Rundlof A-K; Karlsson A; Lundberg M
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2013;288(7):5072-5079
Transgene Expression of Drosophila melanogaster Nucleoside Kinase Reverses Mitochondrial Thymidine Kinase 2 Deficiency
Krishnan S; Zhou X; Paredes JA; Kuiper RV; Curbo S; Karlsson A
Article: PLOS ONE. 2013;8(3):e58843
Thymidine Kinase 2 Deficiency-Induced mtDNA Depletion in Mouse Liver Leads to Defect β-Oxidation
Zhou X; Kannisto K; Curbo S; von Dobeln U; Hultenby K; Isetun S; Gafvels M; Karlsson A
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2009;390(4):1272-1277
Regulation of interleukin-4 signaling by extracellular reduction of intramolecular disulfides
Curbo S; Gaudin R; Carlsten M; Malmberg K-J; Troye-Blomberg M; Ahlborg N; Karlsson A; Johansson M; Lundberg M
Article: EXPERIMENTAL CELL RESEARCH. 2009;315(15):2539-2543
Acute cytotoxicity of arabinofuranosyl nucleoside analogs is not dependent on mitochondrial DNA
Curbo S; Johansson M; Balzarini J; Lewis LD; Karlsson A
Article: GENOMICS. 2006;87(3):410-416
Human mitochondrial pyrophosphatase: cDNA cloning and analysis of the gene in patients with mtDNA depletion syndromes
Curbo S; Lagier-Tourenne C; Carrozzo R; Palenzuela L; Lucioli S; Hirano M; Santorelli F; Arenas J; Karlsson A; Johansson M
Journal article: CHEMINFORM. 2005;36(12):no
5‐Fluoro‐2′‐deoxyuridine Has Effects on Mitochondria in CEM T‐Lymphoblast Cells
Curbo S; Johansson M; Karlsson A
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2003;311(2):440-445
The Drosophila melanogaster UMP-CMP kinase cDNA encodes an N-terminal mitochondrial import signal
Curbo S; Amiri M; Foroogh F; Johansson M; Karlsson A
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2003;307(4):942-947
Effects of 9-β-D-arabinofuranosylguanine on mitochondria in CEM T-lymphoblast leukemia cells
Curbo S; Zhivotovsky B; Johansson M; Karlsson A
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2001;285(1):40-45
Dual mechanisms of 9-β-D-arabinofuranosylguanine resistance in CEM T-lymphoblast leukemia cells
Curbo S; Zhu CY; Johansson M; Balzarini J; Karlsson A
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Conference publication: MITOCHONDRION. 2012;12(5):561-562
Thymidine kinase 2 deficiency-induced mtDNA depletion in liver leads to defect β-oxidation and insufficient supply of ketone bodies and glucose for brain function
Curbo S; Curbo S; Zhou X; Kannisto K; von Dobeln U; Hultenby K; Isetun S; Gafvels M; Karlsson A
Book chapter: DEOXYNUCLEOSIDE ANALOGS IN CANCER THERAPY: CANCER DRUG DISCOVERY AND DEVELOPMENT. 2007;p. 215-224
9-β-D-Arabinofuranosylguanine
Curbo S; Karlsson A
Review: REVIEWS ON RECENT CLINICAL TRIALS. 2006;1(3):185-192
Nelarabine: a new purine analog in the treatment of hematologic malignancies.
Curbo S; Karlsson A
Published conference paper: NUCLEOSIDES, NUCLEOTIDES AND NUCLEIC ACIDS. 2004;23(8-9):1495-1498
5-Fluoro-2′-deoxyuridine has effects on mitochondria in CEM T-lymphoblast cells
Curbo S; Johansson M; Karlsson A
Thesis / dissertation: 2004
Nucleoside analog phosphorylation and mitochondrial enzymes : studies on molecular targets of the anti-leukemic compound 9-beta-D-arabinofuranosylguanine
Curbo, Sophie

Employments

Assistant Senior Lecturer, Department of Laboratory Medicine, Karolinska Institutet, 2022-

Degrees and Education

Doctor Of Philosophy, Department of Laboratory Medicine, Karolinska Institutet, 2004

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