Simon Kebede Merid

About me
Publications
CV
Public outreach and news

About me

I am giving bioinformatics support for Department of Clinical Sciences and
Education.
2010 -Msc. Applied Statistics, Örebro University
2013-Msc. Bioinformatics, Stockholm University
2022-PhD. Department of Clinical Sciences and Education, Karolinska
Institutet

Articles

Article: CLINICAL NUTRITION. 2024;43(5):1162-1170

Arachidonic acid and docosahexaenoic acid levels correlate with the inflammation proteome in extremely preterm infants.

Klevebro S; Kebede Merid S; Sjöbom U; Zhong W; Danielsson H; Wackernagel D; Hansen-Pupp I; Ley D; Sävman K; Uhlén M; Smith LEH; Hellström A; Nilsson AK
Article: ERJ OPEN RESEARCH. 2024;10(1):00701-02023

Lung function in young adulthood in relation to moderate-to-late preterm birth.

Lundberg B; Merid SK; Um-Bergström P; Wang G; Bergström A; Ekström S; Kull I; Melén E; Hallberg J
Article: EPIGENETICS. 2023;18(1):2202835

A meta-analysis of epigenome-wide association studies on pregnancy vitamin B12 concentrations and offspring DNA methylation.

Monasso GS; Hoang TT; Mancano G; Fernández-Barrés S; Dou J; Jaddoe VWV; Page CM; Johnson L; Bustamante M; Bakulski KM; Håberg SE; Ueland PM; Battram T; Merid SK; Melén E; Caramaschi D; Küpers LK; Sunyer J; Nystad W; Heil SG; Schmidt RJ; Vrijheid M; Sharp GC; London SJ; Felix JF
Article: CLINICAL EPIGENETICS. 2023;15(1):148

Analysis of DNA methylation at birth and in childhood reveals changes associated with season of birth and latitude.

Kadalayil L; Alam MZ; White CH; Ghantous A; Walton E; Gruzieva O; Merid SK; Kumar A; Roy RP; Solomon O; Huen K; Eskenazi B; Rzehak P; Grote V; Langhendries J-P; Verduci E; Ferre N; Gruszfeld D; Gao L; Guan W; Zeng X; Schisterman EF; Dou JF; Bakulski KM; Feinberg JI; Soomro MH; Pesce G; Baiz N; Isaevska E; Plusquin M; Vafeiadi M; Roumeliotaki T; Langie SAS; Standaert A; Allard C; Perron P; Bouchard L; van Meel ER; Felix JF; Jaddoe VWV; Yousefi PD; Ramlau-Hansen CH; Relton CL; Tobi EW; Starling AP; Yang IV; Llambrich M; Santorelli G; Lepeule J; Salas LA; Bustamante M; Ewart SL; Zhang H; Karmaus W; Röder S; Zenclussen AC; Jin J; Nystad W; Page CM; Magnus M; Jima DD; Hoyo C; Maguire RL; Kvist T; Czamara D; Räikkönen K; Gong T; Ullemar V; Rifas-Shiman SL; Oken E; Almqvist C; Karlsson R; Lahti J; Murphy SK; Håberg SE; London S; Herberth G; Arshad H; Sunyer J; Grazuleviciene R; Dabelea D; Steegers-Theunissen RPM; Nohr EA; Sørensen TIA; Duijts L; Hivert M-F; Nelen V; Popovic M; Kogevinas M; Nawrot TS; Herceg Z; Annesi-Maesano I; Fallin MD; Yeung E; Breton CV; Koletzko B; Holland N; Wiemels JL; Melén E; Sharp GC; Silver MJ; Rezwan FI; Holloway JW
Article: ALLERGY. 2023;78(9):2533-2536

Innate lymphoid cells type 2 and CD8+ T cells are perturbed in overweight and obese individuals with asthma.

Björkander S; Maier P; Kere M; Merid SK; Wirth L; Wiegel W; Ekström S; Kull I; Bergström A; Melén E; Mjösberg J; Tibbitt CA
Article: EUROPEAN RESPIRATORY JOURNAL. 2023;61(5):2201783

Associations of improved air quality with lung function growth from childhood to adulthood: the BAMSE study.

Yu Z; Merid SK; Bellander T; Bergström A; Eneroth K; Georgelis A; Hallberg J; Kull I; Ljungman P; Klevebro S; Stafoggia M; Wang G; Pershagen G; Gruzieva O; Melén E
Article: AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. 2023;207(5):544-552

Creatine Kinase Is Decreased in Childhood Asthma.

Guerra S; Ledford JG; Melén E; Lavi I; Carsin A-E; Stern DA; Zhai J; Vidal M; Bustamante M; Addison KJ; Vallecillo RG; Billheimer D; Koppelman GH; Garcia-Aymerich J; Lemonnier N; Fitó M; Dobaño C; Kebede Merid S; Kull I; McEachan RRC; Wright J; Chatzi L; Kogevinas M; Porta D; Narduzzi S; Ballester F; Esplugues A; Zabaleta C; Irizar A; Sunyer J; Halonen M; Bousquet J; Martinez FD; Anto JM
Article: AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. 2023;207(4):406-415

Plasticity of Individual Lung Function States from Childhood to Adulthood.

Wang G; Hallberg J; Faner R; Koefoed H-J; Kebede Merid S; Klevebro S; Björkander S; Gruzieva O; Pershagen G; van Hage M; Guerra S; Bottai M; Georgelis A; Gehring U; Bergström A; Vonk JM; Kull I; Koppelman GH; Agusti A; Melén E
Article: CLINICAL EPIGENETICS. 2022;14(1):114

DNA methylation and aeroallergen sensitization: The chicken or the egg?

Kilanowski A; Merid SK; Abrishamcar S; Feil D; Thiering E; Waldenberger M; Melén E; Peters A; Standl M; Hüls A
Article: AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY. 2022;66(6):638-647

Chronic Obstructive Pulmonary Disease Is Associated with Epigenome-Wide Differential Methylation in BAL Lung Cells.

Eriksson Ström J; Kebede Merid S; Pourazar J; Blomberg A; Lindberg A; Ringh MV; Hagemann-Jensen M; Ekström TJ; Behndig AF; Melén E
Article: PEDIATRIC ALLERGY AND IMMUNOLOGY. 2022;33(1):e13682

Transcriptome changes during peanut oral immunotherapy and omalizumab treatment.

Björkander S; Merid SK; Brodin D; Brandström J; Fagerström-Billai F; van der Heiden M; Konradsen JR; Kabesch M; van Drunen CM; Golebski K; Maitland-van der Zee AH; Potočnik U; Vijverberg SJH; Nopp A; Nilsson C; Melén E
Article: SCANDINAVIAN JOURNAL OF PUBLIC HEALTH. 2021;49(7):707-712

Risk of SARS-CoV-2 exposure among hospital healthcare workers in relation to patient contact and type of care.

Klevebro S; Bahram F; Elfström KM; Hellberg U; Hober S; Merid SK; Kull I; Nilsson P; Tornvall P; Wang G; Conneryd Lundgren K; Ponzer S; Dillner J; Melén E
Article: ERJ OPEN RESEARCH. 2021;7(4):381-2021

Expert meeting report: towards a joint European roadmap to address the unmet needs and priorities of paediatric asthma patients on biologic therapy.

Golebski K; Dankelman LHM; Björkander S; Bønnelykke K; Brinkman P; Deschildre A; van Dijk YE; Fleming L; Grigg J; Hamelmann E; Hashimoto S; Kabesch M; Klevebro S; Maitland-van der Zee A-H; Merid SK; Nieto A; Niggel J; Nilsson C; Potočnik U; Roberts G; Rusconi F; Saglani S; Valente E; van Drunen C; Wang G; Melén E; Vijverberg SJH
Article: SCIENTIFIC REPORTS. 2021;11(1):11391

Inflammation-related plasma protein levels and association with adiposity measurements in young adults.

Klevebro S; Björkander S; Ekström S; Merid SK; Gruzieva O; Mälarstig A; Johansson Å; Kull I; Bergström A; Melén E
Article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2021;147(4):1510-1513.e8

Inverse association of FCER1A allergy variant in monocytes and plasmacytoid dendritic cells.

Andiappan AK; Puan KJ; Lee B; Yeow PT; Yusof N; Merid SK; Kumar D; Lum J; Foo S; Koh G; Poidinger M; Zolezzi F; eQTLGen Consortium; BIOS Consortium; Wang DY; Melén E; Rotzschke O
Article: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2021;22(2):E801-801

DNA Methylation Levels in Mononuclear Leukocytes from the Mother and Her Child Are Associated with IgE Sensitization to Allergens in Early Life.

Acevedo N; Scala G; Merid SK; Frumento P; Bruhn S; Andersson A; Ogris C; Bottai M; Pershagen G; Koppelman GH; Melén E; Sonnhammer E; Alm J; Söderhäll C; Kere J; Greco D; Scheynius A
Article: ENVIRONMENT INTERNATIONAL. 2021;146:106248

Integration of gene expression and DNA methylation identifies epigenetically controlled modules related to PM2.5 exposure.

Merid SK; Bustamante M; Standl M; Sunyer J; Heinrich J; Lemonnier N; Aguilar D; Antó JM; Bousquet J; Santa-Marina L; Lertxundi A; Bergström A; Kull I; Wheelock ÅM; Koppelman GH; Melén E; Gruzieva O
Article: RESPIRATORY RESEARCH. 2020;21(1):80

Changes of DNA methylation are associated with changes in lung function during adolescence.

Sunny SK; Zhang H; Rezwan FI; Relton CL; Henderson AJ; Merid SK; Melén E; Hallberg J; Arshad SH; Ewart S; Holloway JW
Article: GENOME MEDICINE. 2020;12(1):25

Epigenome-wide meta-analysis of blood DNA methylation in newborns and children identifies numerous loci related to gestational age.

Merid SK; Novoloaca A; Sharp GC; Küpers LK; Kho AT; Roy R; Gao L; Annesi-Maesano I; Jain P; Plusquin M; Kogevinas M; Allard C; Vehmeijer FO; Kazmi N; Salas LA; Rezwan FI; Zhang H; Sebert S; Czamara D; Rifas-Shiman SL; Melton PE; Lawlor DA; Pershagen G; Breton CV; Huen K; Baiz N; Gagliardi L; Nawrot TS; Corpeleijn E; Perron P; Duijts L; Nohr EA; Bustamante M; Ewart SL; Karmaus W; Zhao S; Page CM; Herceg Z; Jarvelin M-R; Lahti J; Baccarelli AA; Anderson D; Kachroo P; Relton CL; Bergström A; Eskenazi B; Soomro MH; Vineis P; Snieder H; Bouchard L; Jaddoe VW; Sørensen TIA; Vrijheid M; Arshad SH; Holloway JW; Håberg SE; Magnus P; Dwyer T; Binder EB; DeMeo DL; Vonk JM; Newnham J; Tantisira KG; Kull I; Wiemels JL; Heude B; Sunyer J; Nystad W; Munthe-Kaas MC; Räikkönen K; Oken E; Huang R-C; Weiss ST; Antó JM; Bousquet J; Kumar A; Söderhäll C; Almqvist C; Cardenas A; Gruzieva O; Xu C-J; Reese SE; Kere J; Brodin P; Solomon O; Wielscher M; Holland N; Ghantous A; Hivert M-F; Felix JF; Koppelman GH; London SJ; Melén E
Article: CLINICAL AND EXPERIMENTAL ALLERGY. 2019;49(9):1225-1234

DNA methylation is associated with inhaled corticosteroid response in persistent childhood asthmatics.

Wang AL; Gruzieva O; Qiu W; Kebede Merid S; Celedón JC; Raby BA; Söderhäll C; DeMeo DL; Weiss ST; Melén E; Tantisira KG
Article: ALLERGY. 2019;74(6):1166-1175

DNA methylation and allergic sensitizations: A genome-scale longitudinal study during adolescence.

Zhang H; Kaushal A; Merid SK; Melén E; Pershagen G; Rezwan FI; Han L; Ewart S; Arshad SH; Karmaus W; Holloway JW
Article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2019;143(6):2062-2074

Epigenome-wide meta-analysis of DNA methylation and childhood asthma.

Reese SE; Xu C-J; den Dekker HT; Lee MK; Sikdar S; Ruiz-Arenas C; Merid SK; Rezwan FI; Page CM; Ullemar V; Melton PE; Oh SS; Yang IV; Burrows K; Söderhäll C; Jima DD; Gao L; Arathimos R; Küpers LK; Wielscher M; Rzehak P; Lahti J; Laprise C; Madore A-M; Ward J; Bennett BD; Wang T; Bell DA; BIOS consortium; Vonk JM; Håberg SE; Zhao S; Karlsson R; Hollams E; Hu D; Richards AJ; Bergström A; Sharp GC; Felix JF; Bustamante M; Gruzieva O; Maguire RL; Gilliland F; Baïz N; Nohr EA; Corpeleijn E; Sebert S; Karmaus W; Grote V; Kajantie E; Magnus MC; Örtqvist AK; Eng C; Liu AH; Kull I; Jaddoe VWV; Sunyer J; Kere J; Hoyo C; Annesi-Maesano I; Arshad SH; Koletzko B; Brunekreef B; Binder EB; Räikkönen K; Reischl E; Holloway JW; Jarvelin M-R; Snieder H; Kazmi N; Breton CV; Murphy SK; Pershagen G; Anto JM; Relton CL; Schwartz DA; Burchard EG; Huang R-C; Nystad W; Almqvist C; Henderson AJ; Melén E; Duijts L; Koppelman GH; London SJ
Article: EUROPEAN RESPIRATORY JOURNAL. 2019;53(5):1900102

Transcriptomics of atopy and atopic asthma in white blood cells from children and adolescents.

Jiang Y; Gruzieva O; Wang T; Forno E; Boutaoui N; Sun T; Merid SK; Acosta-Pérez E; Kull I; Canino G; Antó JM; Bousquet J; Melén E; Chen W; Celedón JC
Article: ENVIRONMENTAL HEALTH PERSPECTIVES. 2019;127(5):57012

Prenatal Particulate Air Pollution and DNA Methylation in Newborns: An Epigenome-Wide Meta-Analysis.

Gruzieva O; Xu C-J; Yousefi P; Relton C; Merid SK; Breton CV; Gao L; Volk HE; Feinberg JI; Ladd-Acosta C; Bakulski K; Auffray C; Lemonnier N; Plusquin M; Ghantous A; Herceg Z; Nawrot TS; Pizzi C; Richiardi L; Rusconi F; Vineis P; Kogevinas M; Felix JF; Duijts L; den Dekker HT; Jaddoe VWV; Ruiz JL; Bustamante M; Antó JM; Sunyer J; Vrijheid M; Gutzkow KB; Grazuleviciene R; Hernandez-Ferrer C; Annesi-Maesano I; Lepeule J; Bousquet J; Bergström A; Kull I; Söderhäll C; Kere J; Gehring U; Brunekreef B; Just AC; Wright RJ; Peng C; Gold DR; Kloog I; DeMeo DL; Pershagen G; Koppelman GH; London SJ; Baccarelli AA; Melén E
Article: NATURE COMMUNICATIONS. 2019;10(1):1893

Meta-analysis of epigenome-wide association studies in neonates reveals widespread differential DNA methylation associated with birthweight.

Küpers LK; Monnereau C; Sharp GC; Yousefi P; Salas LA; Ghantous A; Page CM; Reese SE; Wilcox AJ; Czamara D; Starling AP; Novoloaca A; Lent S; Roy R; Hoyo C; Breton CV; Allard C; Just AC; Bakulski KM; Holloway JW; Everson TM; Xu C-J; Huang R-C; van der Plaat DA; Wielscher M; Merid SK; Ullemar V; Rezwan FI; Lahti J; van Dongen J; Langie SAS; Richardson TG; Magnus MC; Nohr EA; Xu Z; Duijts L; Zhao S; Zhang W; Plusquin M; DeMeo DL; Solomon O; Heimovaara JH; Jima DD; Gao L; Bustamante M; Perron P; Wright RO; Hertz-Picciotto I; Zhang H; Karagas MR; Gehring U; Marsit CJ; Beilin LJ; Vonk JM; Jarvelin M-R; Bergström A; Örtqvist AK; Ewart S; Villa PM; Moore SE; Willemsen G; Standaert ARL; Håberg SE; Sørensen TIA; Taylor JA; Räikkönen K; Yang IV; Kechris K; Nawrot TS; Silver MJ; Gong YY; Richiardi L; Kogevinas M; Litonjua AA; Eskenazi B; Huen K; Mbarek H; Maguire RL; Dwyer T; Vrijheid M; Bouchard L; Baccarelli AA; Croen LA; Karmaus W; Anderson D; de Vries M; Sebert S; Kere J; Karlsson R; Arshad SH; Hämäläinen E; Routledge MN; Boomsma DI; Feinberg AP; Newschaffer CJ; Govarts E; Moisse M; Fallin MD; Melén E; Prentice AM; Kajantie E; Almqvist C; Oken E; Dabelea D; Boezen HM; Melton PE; Wright RJ; Koppelman GH; Trevisi L; Hivert M-F; Sunyer J; Munthe-Kaas MC; Murphy SK; Corpeleijn E; Wiemels J; Holland N; Herceg Z; Binder EB; Davey Smith G; Jaddoe VWV; Lie RT; Nystad W; London SJ; Lawlor DA; Relton CL; Snieder H; Felix JF
Article: EPIGENETICS INSIGHTS. 2019;12:2516865719867090-251686571986709

DNA Methylation Trajectories During Pregnancy.

Gruzieva O; Merid SK; Chen S; Mukherjee N; Hedman AM; Almqvist C; Andolf E; Jiang Y; Kere J; Scheynius A; Söderhäll C; Ullemar V; Karmaus W; Melén E; Arshad SH; Pershagen G
Article: PHARMACOGENOMICS. 2018;19(8):707-713

Variants in genes coding for glutathione S-transferases and asthma outcomes in children.

Turner S; Francis B; Wani N; Vijverberg S; Pino-Yanes M; Mukhopadhyay S; Tavendale R; Palmer C; Burchard EG; Merid SK; Melén E; Maitland-van der Zee AH; The Pharmacogenomics In Childhood Asthma Consortiu OBO
Article: LANCET RESPIRATORY MEDICINE. 2018;6(5):379-388

DNA methylation in childhood asthma: an epigenome-wide meta-analysis.

Xu C-J; Söderhäll C; Bustamante M; Baïz N; Gruzieva O; Gehring U; Mason D; Chatzi L; Basterrechea M; Llop S; Torrent M; Forastiere F; Fantini MP; Carlsen KCL; Haahtela T; Morin A; Kerkhof M; Merid SK; van Rijkom B; Jankipersadsing SA; Bonder MJ; Ballereau S; Vermeulen CJ; Aguirre-Gamboa R; de Jongste JC; Smit HA; Kumar A; Pershagen G; Guerra S; Garcia-Aymerich J; Greco D; Reinius L; McEachan RRC; Azad R; Hovland V; Mowinckel P; Alenius H; Fyhrquist N; Lemonnier N; Pellet J; Auffray C; BIOS Consortium; van der Vlies P; van Diemen CC; Li Y; Wijmenga C; Netea MG; Moffatt MF; Cookson WOCM; Anto JM; Bousquet J; Laatikainen T; Laprise C; Carlsen K-H; Gori D; Porta D; Iñiguez C; Bilbao JR; Kogevinas M; Wright J; Brunekreef B; Kere J; Nawijn MC; Annesi-Maesano I; Sunyer J; Melén E; Koppelman GH
Article: SCIENTIFIC REPORTS. 2017;7(1):15693

Hypomethylation of HOXA4 promoter is common in Silver-Russell syndrome and growth restriction and associates with stature in healthy children.

Muurinen M; Hannula-Jouppi K; Reinius LE; Söderhäll C; Merid SK; Bergström A; Melén E; Pershagen G; Lipsanen-Nyman M; Greco D; Kere J
Article: HUMAN MOLECULAR GENETICS. 2017;26(20):4067-4085

Maternal BMI at the start of pregnancy and offspring epigenome-wide DNA methylation: findings from the pregnancy and childhood epigenetics (PACE) consortium.

Sharp GC; Salas LA; Monnereau C; Allard C; Yousefi P; Everson TM; Bohlin J; Xu Z; Huang R-C; Reese SE; Xu C-J; Baïz N; Hoyo C; Agha G; Roy R; Holloway JW; Ghantous A; Merid SK; Bakulski KM; Küpers LK; Zhang H; Richmond RC; Page CM; Duijts L; Lie RT; Melton PE; Vonk JM; Nohr EA; Williams-DeVane C; Huen K; Rifas-Shiman SL; Ruiz-Arenas C; Gonseth S; Rezwan FI; Herceg Z; Ekström S; Croen L; Falahi F; Perron P; Karagas MR; Quraishi BM; Suderman M; Magnus MC; Jaddoe VWV; Taylor JA; Anderson D; Zhao S; Smit HA; Josey MJ; Bradman A; Baccarelli AA; Bustamante M; Håberg SE; Pershagen G; Hertz-Picciotto I; Newschaffer C; Corpeleijn E; Bouchard L; Lawlor DA; Maguire RL; Barcellos LF; Davey Smith G; Eskenazi B; Karmaus W; Marsit CJ; Hivert M-F; Snieder H; Fallin MD; Melén E; Munthe-Kaas MC; Arshad H; Wiemels JL; Annesi-Maesano I; Vrijheid M; Oken E; Holland N; Murphy SK; Sørensen TIA; Koppelman GH; Newnham JP; Wilcox AJ; Nystad W; London SJ; Felix JF; Relton CL
Article: ENVIRONMENTAL HEALTH PERSPECTIVES. 2017;125(6):067007

Exposure to Traffic-Related Air Pollution and Serum Inflammatory Cytokines in Children.

Gruzieva O; Merid SK; Gref A; Gajulapuri A; Lemonnier N; Ballereau S; Gigante B; Kere J; Auffray C; Melén E; Pershagen G
Article: AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. 2017;195(10):1373-1383

Genome-Wide Interaction Analysis of Air Pollution Exposure and Childhood Asthma with Functional Follow-up.

Gref A; Merid SK; Gruzieva O; Ballereau S; Becker A; Bellander T; Bergström A; Bossé Y; Bottai M; Chan-Yeung M; Fuertes E; Ierodiakonou D; Jiang R; Joly S; Jones M; Kobor MS; Korek M; Kozyrskyj AL; Kumar A; Lemonnier N; MacIntyre E; Ménard C; Nickle D; Obeidat M; Pellet J; Standl M; Sääf A; Söderhäll C; Tiesler CMT; van den Berge M; Vonk JM; Vora H; Xu C-J; Antó JM; Auffray C; Brauer M; Bousquet J; Brunekreef B; Gauderman WJ; Heinrich J; Kere J; Koppelman GH; Postma D; Carlsten C; Pershagen G; Melén E
Article: ENVIRONMENTAL HEALTH PERSPECTIVES. 2017;125(1):104-110

Epigenome-Wide Meta-Analysis of Methylation in Children Related to Prenatal NO2 Air Pollution Exposure.

Gruzieva O; Xu C-J; Breton CV; Annesi-Maesano I; Antó JM; Auffray C; Ballereau S; Bellander T; Bousquet J; Bustamante M; Charles M-A; de Kluizenaar Y; den Dekker HT; Duijts L; Felix JF; Gehring U; Guxens M; Jaddoe VVW; Jankipersadsing SA; Merid SK; Kere J; Kumar A; Lemonnier N; Lepeule J; Nystad W; Page CM; Panasevich S; Postma D; Slama R; Sunyer J; Söderhäll C; Yao J; London SJ; Pershagen G; Koppelman GH; Melén E
Article: PLOS ONE. 2017;12(5):e0176568

Neuropeptide S (NPS) variants modify the signaling and risk effects of NPS Receptor 1 (NPSR1) variants in asthma.

Acevedo N; Ezer S; Kebede Merid S; Gaertner VD; Söderhäll C; D'Amato M; Kabesch M; Melén E; Kere J; Pulkkinen V
Article: RESPIRATORY RESEARCH. 2016;17(1):95

Genes associated with polymorphic variants predicting lung function are differentially expressed during human lung development.

Miller S; Melén E; Merid SK; Hall IP; Sayers I
Article: AMERICAN JOURNAL OF HUMAN GENETICS. 2016;98(4):680-696

DNA Methylation in Newborns and Maternal Smoking in Pregnancy: Genome-wide Consortium Meta-analysis.

Joubert BR; Felix JF; Yousefi P; Bakulski KM; Just AC; Breton C; Reese SE; Markunas CA; Richmond RC; Xu C-J; Küpers LK; Oh SS; Hoyo C; Gruzieva O; Söderhäll C; Salas LA; Baïz N; Zhang H; Lepeule J; Ruiz C; Ligthart S; Wang T; Taylor JA; Duijts L; Sharp GC; Jankipersadsing SA; Nilsen RM; Vaez A; Fallin MD; Hu D; Litonjua AA; Fuemmeler BF; Huen K; Kere J; Kull I; Munthe-Kaas MC; Gehring U; Bustamante M; Saurel-Coubizolles MJ; Quraishi BM; Ren J; Tost J; Gonzalez JR; Peters MJ; Håberg SE; Xu Z; van Meurs JB; Gaunt TR; Kerkhof M; Corpeleijn E; Feinberg AP; Eng C; Baccarelli AA; Benjamin Neelon SE; Bradman A; Merid SK; Bergström A; Herceg Z; Hernandez-Vargas H; Brunekreef B; Pinart M; Heude B; Ewart S; Yao J; Lemonnier N; Franco OH; Wu MC; Hofman A; McArdle W; Van der Vlies P; Falahi F; Gillman MW; Barcellos LF; Kumar A; Wickman M; Guerra S; Charles M-A; Holloway J; Auffray C; Tiemeier HW; Smith GD; Postma D; Hivert M-F; Eskenazi B; Vrijheid M; Arshad H; Antó JM; Dehghan A; Karmaus W; Annesi-Maesano I; Sunyer J; Ghantous A; Pershagen G; Holland N; Murphy SK; DeMeo DL; Burchard EG; Ladd-Acosta C; Snieder H; Nystad W; Koppelman GH; Relton CL; Jaddoe VWV; Wilcox A; Melén E; London SJ
Article: INTERNATIONAL JOURNAL OF MOLECULAR EPIDEMIOLOGY AND GENETICS. 2016;7(1):1-17

DNA methylation and genetic polymorphisms of the Leptin gene interact to influence lung function outcomes and asthma at 18 years of age.

Mukherjee N; Lockett GA; Merid SK; Melén E; Pershagen G; Holloway JW; Arshad SH; Ewart S; Zhang H; Karmaus W
Article: PLOS ONE. 2016;11(10):e0164041

The Ser82 RAGE Variant Affects Lung Function and Serum RAGE in Smokers and sRAGE Production In Vitro.

Miller S; Henry AP; Hodge E; Kheirallah AK; Billington CK; Rimington TL; Bhaker SK; Obeidat M; Melén E; Merid SK; Swan C; Gowland C; Nelson CP; Stewart CE; Bolton CE; Kilty I; Malarstig A; Parker SG; Moffatt MF; Wardlaw AJ; Hall IP; Sayers I
Article: GENOME MEDICINE. 2015;7(1):89

DNA methylation loci associated with atopy and high serum IgE: a genome-wide application of recursive Random Forest feature selection.

Everson TM; Lyons G; Zhang H; Soto-Ramírez N; Lockett GA; Patil VK; Merid SK; Söderhäll C; Melén E; Holloway JW; Arshad SH; Karmaus W
Article: BMC BIOINFORMATICS. 2014;15(1):308

Distinguishing between driver and passenger mutations in individual cancer genomes by network enrichment analysis.

Merid SK; Goranskaya D; Alexeyenko A
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All other publications

Review: LANCET. 2024;403(10435):1494-1503

Lung-function trajectories: relevance and implementation in clinical practice.

Melén E; Faner R; Allinson JP; Bui D; Bush A; Custovic A; Garcia-Aymerich J; Guerra S; Breyer-Kohansal R; Hallberg J; Lahousse L; Martinez FD; Merid SK; Powell P; Pinnock H; Stanojevic S; Vanfleteren LEGW; Wang G; Dharmage SC; Wedzicha J; Agusti A; CADSET Investigators
Letter: ALLERGY. 2023;78(10):2794-2798

Eosinophilic allergic rhinitis is strongly associated with the CD45RBlo subset of CD161+ Th2 cells that secretes IL-2, IL-3, IL-4, IL-5, IL-9, and IL-13.

Lee WWL; Puan KJ; Lee B; Chua C; Koh SM; Yusof N; Tan KP; Luis BS; Ong J; Merid SK; Ang R; Chan XY; Hui LJ; Terenzani E; Lum J; Foo S; Zolezzi F; Yan ATS; Melen E; Yi SJ; Rotzschke O; Andiappan AK
Thesis / dissertation: 2022

Molecular signatures of early life exposures and complex diseases : applications using epigenetics and transcriptomics data

Merid, Simon Kebede
Review: CURRENT OPINION IN ALLERGY AND CLINICAL IMMUNOLOGY. 2021;21(2):175-181

An update on the epigenetics of asthma.

Gruzieva O; Merid SK; Koppelman GH; Melén E
Letter: ALLERGY. 2018;73(10):2083-2088

17q21 variant increases the risk of exacerbations in asthmatic children despite inhaled corticosteroids use.

Farzan N; Vijverberg SJ; Hernandez-Pacheco N; Bel EHD; Berce V; Bønnelykke K; Bisgaard H; Burchard EG; Canino G; Celedón JC; Chew FT; Chiang WC; Cloutier MM; Forno E; Francis B; Hawcutt DB; Herrera-Luis E; Kabesch M; Karimi L; Melén E; Mukhopadhyay S; Merid SK; Palmer CN; Pino-Yanes M; Pirmohamed M; Potočnik U; Repnik K; Schieck M; Sevelsted A; Sio YY; Smyth RL; Soares P; Söderhäll C; Tantisira KG; Tavendale R; Tse SM; Turner S; Verhamme KM; Maitland-van der Zee A-H
Review: PAEDIATRIC RESPIRATORY REVIEWS. 2014;15(4):348-354

An update on epigenetics and childhood respiratory diseases.

Gruzieva O; Merid SK; Melén E

Degrees and Education

Degree Of Doctor Of Philosophy, Department of Clinical Science and Education, Södersjukhuset, Karolinska Institutet, 2023

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