Sebastian Gidlöf

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About me

Sebastian Gidlöf studied medicine at the Karolinska Institutet in Stockholm and obtained his medical degree in 2008. He defended his doctoral thesis in endocrinology at the Karolinska Institutet in 2013 and works as the Head of Department of Gynecology and Reproductive Medicine at the Karolinska University Hospital. He has received several research grants and was previously responsible for the course in Obstetrics and Gynecology for medical students at Karolinska Institutet. In 2016, Dr. Gidlöf received the NFOG Young Scientist Award and since 2014 he is a member of the editorial board of AOGS - Acta Obstetricia et Gynecologica Scandinavica. His research is primarily focused on translational and clinical studies in reproductive endocrinology and immunology and focuses on the physiology of the endometrium and its importance for pregnancy outcomes and disease development.

Articles

Article: SCIENCE IMMUNOLOGY. 2024;9(94):eadj7168
Tissue-specific nonheritable influences drive endometrial immune system variation
Bister J; Filipovic I; Sun D; Crona-Guterstam Y; Cornillet M; Ponzetta A; Michaelsson J; Gidloef S; Ivarsson MA; Strunz B; Bjoerkstroem NK
Article: HORMONE RESEARCH IN PAEDIATRICS. 2024;97(5):445-455
Growth and Treatment in Congenital Adrenal Hyperplasia: An Observational Study from Diagnosis to Final Height
Gidloef S; Hogling DE; Lonnberg H; Ritzen M; Lajic S; Nordenstrom A
Article: HUMAN REPRODUCTION UPDATE. 2023;29(6):773-793
Endometrial receptivity in women of advanced age: an underrated factor in infertility
Pathare ADS; Loid M; Saare M; Gidloef SB; Zamani Esteki M; Acharya G; Peters M; Salumets A
Article: REPRODUCTIVE BIOMEDICINE ONLINE. 2023;47(4):103287
Reference standards for follicular density in ovarian cortex from birth to sexual maturity
Hassan J; Knuus K; Lahtinen A; Rooda I; Otala M; Tuuri T; Gidlof S; Edlund E; Menezes J; Malmros J; Bystrom P; Sundin M; Langenskiold C; Vogt H; Frisk P; Petersen C; Damdimopoulou P; Jahnukainen K
Article: ENVIRONMENT INTERNATIONAL. 2023;179:108141
Ambient black carbon particles in human ovarian tissue and follicular fluid
Bongaerts E; Mamia K; Rooda I; Bjorvang RD; Papaikonomou K; Gidlof SB; Olofsson JI; Ameloot M; Alfaro-Moreno E; Nawrot TS; Damdimopoulou P
Article: AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY. 2023;90(2):e13738
Immune cell profiling of vaginal blood from patients with early pregnancy bleeding
Guterstam YC; Acharya G; Schott K; Bjorkstrom NK; Gidlof S; Ivarsson MA
Article: REPRODUCTIVE TOXICOLOGY. 2023;119:108393
Identification of phthalate mixture exposure targets in the human and mouse ovary in vitro
Tarvainen I; Soto DA; Laws MJ; Bjorvang RD; Damdimopoulos A; Roos K; Li T; Kramer S; Li Z; Lavogina D; Visser N; Kallak TK; Lager S; Gidlof S; Edlund E; Papaikonomou K; Oberg M; Olovsson M; Salumets A; Velthut-Meikas A; Flaws JA; Damdimopoulou P
Article: SCIENCE TRANSLATIONAL MEDICINE. 2022;14(673):eabm2417
Topical reinforcement of the cervical mucus barrier to sperm
Schimpf U; Caldas-Silveira E; Katchan L; Vigier-Carriere C; Lantier I; Nachmann G; Gidlof S; Jonasson AF; Bjorndahl L; Trombotto S; Druart X; Crouzier T
Article: CHEMOSPHERE. 2021;283:131125
Mixtures of persistent organic pollutants are found in vital organs of late gestation human fetuses
Bjorvang RD; Vinnars M-T; Papadogiannakis N; Gidlof S; Mamsen LS; Mucs D; Kiviranta H; Rantakokko P; Ruokojarvi P; Lindh CH; Andersen CY; Damdimopoulou P
Article: MUCOSAL IMMUNOLOGY. 2021;14(2):357-365
Human endometrial MAIT cells are transiently tissue resident and respond toNeisseria gonorrhoeae
Bister J; Guterstam YC; Strunz B; Dumitrescu B; Bhattarai KH; Ozenci V; Brannstrom M; Ivarsson MA; Gidlof S; Bjorkstrom NK
Article: SCIENCE IMMUNOLOGY. 2021;6(56):eabb7800
Continuous human uterine NK cell differentiation in response to endometrial regeneration and pregnancy
Strunz B; Bister J; Jonsson H; Filipovic I; Crona-Guterstam Y; Kvedaraite E; Sleiers N; Dumitrescu B; Brannstrom M; Lentini A; Reinius B; Cornillet M; Willinger T; Gidlof S; Hamilton RS; Ivarsson MA; Bjorkstrom NK
Article: ACTA OBSTETRICIA ET GYNECOLOGICA SCANDINAVICA. 2021;100(2):339-346
The cytokine profile of menstrual blood
Crona Guterstam Y; Strunz B; Ivarsson MA; Zimmer C; Melin A-S; Jonasson AF; Bjorkstrom NK; Gidlof SB
Article: JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM (JCEM). 2021;106(2):e957-e965
Reproductive and Perinatal Outcomes in Women with Congenital Adrenal Hyperplasia: A Population-based Cohort Study
Hirschberg AL; Gidlof S; Falhammar H; Frisen L; Almqvist C; Nordenskjold A; Nordenstrom A
Article: FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY. 2021;9:612714
The Effect of Mesenchymal Stromal Cells Derived From Endometriotic Lesions on Natural Killer Cell Function
Abomaray F; Wagner AK; Chrobok M; Ekblad-Nordberg A; Gidlof S; Alici E; Gotherstrom C
Article: ACTA OBSTETRICIA ET GYNECOLOGICA SCANDINAVICA. 2020;99(12):1626-1631
Characteristics and short-term obstetric outcomes in a case series of 67 women test-positive for SARS-CoV-2 in Stockholm, Sweden
Remaeus K; Savchenko J; Wendel SB; Gidlof SB; Graner S; Jones E; Molin J; Saltvedt S; Wallstrom T; Pettersson K
Article: REPRODUCTIVE BIOLOGY AND ENDOCRINOLOGY. 2020;18(1):117
Insulin regulation of solute carrier family 2 member 1 (glucose transporter 1) expression and glucose uptake in decidualizing human endometrial stromal cells: an in vitro study
Jakson I; Ujvari D; Gidlof SB; Hirschberg AL
Article: EUROPEAN JOURNAL OF ENDOCRINOLOGY (EJE). 2020;183(1):1-11
Psychological well-being and personality in relation to weight loss following behavioral modification intervention in obese women with polycystic ovary syndrome: a randomized controlled trial
Oberg E; Lundell C; Blomberg L; Gidlof SB; Egnell PT; Hirschberg AL
Article: AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY. 2019;82(3):e13154
Mature naive B cells are retained in the placental intervillous blood and positively associate with specific chemokines in full-term healthy pregnancy
Solders M; Lundell A-C; Gorchs L; Gidlof S; Tiblad E; Kaipe H
Article: CLINICAL ENDOCRINOLOGY. 2019;90(3):468-478
Improved menstrual function in obese women with polycystic ovary syndrome after behavioural modification intervention-A randomized controlled trial
Oberg E; Gidlof S; Jakson I; Mitsell M; Egnell PT; Hirschberg AL
Article: FRONTIERS IN IMMUNOLOGY. 2019;10:1300
Recruitment of MAIT Cells to the Intervillous Space of the Placenta by Placenta-Derived Chemokines
Solders M; Gorchs L; Tiblad E; Gidlof S; Leeansyah E; Dias J; Sandberg JK; Magalhaes I; Lundell A-C; Kaipe H
Article: STEM CELLS INTERNATIONAL. 2018;2018:7318513-12
Mesenchymal Stromal Cells Support Endometriotic Stromal Cells In Vitro
Abomaray F; Gidlof S; Bezubik B; Engman M; Gotherstrom C
Article: JOURNAL OF CELLULAR AND MOLECULAR MEDICINE. 2018;22(1):163-172
Prokineticin 1 is up-regulated by insulin in decidualizing human endometrial stromal cells
Ujvari D; Jakson I; Oldmark C; Attarha S; Alkasalias T; Salamon D; Gidlof S; Hirschberg AL
Article: SCIENTIFIC REPORTS. 2017;7(1):6123
MAIT cells accumulate in placental intervillous space and display a highly cytotoxic phenotype upon bacterial stimulation
Solders M; Gorchs L; Erkers T; Lundell A-C; Nava S; Gidlof S; Tiblad E; Magalhaes I; Kaipe H
Journal article: ACTA OBSTETRICIA ET GYNECOLOGICA SCANDINAVICA. 2017;96(6):787
Hideharu Kanzaki (Editor). Uterine Endometrial Function. 1st edition. 155 pages. Springer, Japan, 2016. ISBN 978‐4‐431‐55972‐6. Hardback. Price €110.
Gidlöf S; Öberg E
Article: MUCOSAL IMMUNOLOGY. 2017;10(2):322-331
Composition and dynamics of the uterine NK cell KIR repertoire in menstrual blood
Ivarsson MA; Stiglund N; Marquardt N; Westgren M; Gidlof S; Bjorkstrom NK
Article: STEM CELLS INTERNATIONAL. 2017;2017:8010961-15
Maternal Adaptive Immune Cells in Decidua Parietalis Display a More Activated and Coinhibitory Phenotype Compared to Decidua Basalis
Solders M; Gorchs L; Gidlof S; Tiblad E; Lundell A-C; Kaipe H
Article: STEM CELLS INTERNATIONAL. 2017;2017:3215962-13
Mesenchymal Stromal Cells Are More Immunosuppressive In Vitro If They Are Derived from Endometriotic Lesions than from Eutopic Endometrium
Abomaray F; Gidlof S; Gotherstrom C
Article: PLOS ONE. 2017;12(1):e0171004
Dysregulation of In Vitro Decidualization of Human Endometrial Stromal Cells by Insulin via Transcriptional Inhibition of Forkhead Box Protein O1
Ujvari D; Jakson I; Babayeva S; Salamon D; Rethi B; Gidlof S; Hirschberg AL
Article: BIOLOGY OF REPRODUCTION. 2017;96(1):24-33
Comprehensive RNA sequencing of healthy human endometrium at two time points of the menstrual cycle
Sigurgeirsson B; Amark H; Jemt A; Ujvari D; Westgren M; Lundeberg J; Gidlof S
Article: BMJ OPEN. 2016;6(9):e009733
Maternal vitamin D deficiency and fetal distress/birth asphyxia: a population-based nested case-control study
Lindqvist PG; Silva AT; Gustafsson SA; Gidlof S
Article: ACTA OBSTETRICIA ET GYNECOLOGICA SCANDINAVICA. 2015;94(8):904-908
Vitamin D and the risk of preeclampsia - a nested case-control study
Gidlof S; Silva AT; Gustafsson S; Lindqvist PG
Article: JAMA PEDIATRICS. 2014;168(6):567-574
Nationwide Neonatal Screening for Congenital Adrenal Hyperplasia in Sweden A 26-Year Longitudinal Prospective Population-Based Study
Gidlof S; Wedell A; Guthenberg C; von Dobeln U; Nordenstrom A
Article: THE LANCET DIABETES AND ENDOCRINOLOGY. 2013;1(1):35-42
One hundred years of congenital adrenal hyperplasia in Sweden: a retrospective, population-based cohort study
Gidlof S; Falhammar H; Thilen A; von Dobeln U; Ritzen M; Wedell A; Nordenstrom A
Journal article: ACTA OBSTETRICIA ET GYNECOLOGICA SCANDINAVICA. 2011;90(4):415
BOOK REVIEW
Gidlöf S; Nisell H
Article: LAKARTIDNINGEN. 2010;107(51-52):3288-3292
[Pre-eclampsia].
Gidlöf S; Nisell H
Article: ARCHIVES OF DISEASE IN CHILDHOOD: FETAL AND NEONATAL EDITION. 2010;95(6):F435-F438
The role of androgens in fetal growth: observational study in two genetic models of disordered androgen signalling
Miles HL; Gidlof S; Nordenstrom A; Ong KK; Hughes IA
Article: JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM (JCEM). 2007;92(1):246-249
Gestational age correlates to genotype in girls with CYP21 deficiency
Gidlof S; Wedell A; Nordenstrom A
Article: NATURE. 2004;429(6990):417-423
Premature ageing in mice expressing defective mitochondrial DNA polymerase
Trifunovic A; Wredenberg A; Falkenberg M; Spelbrink JN; Rovio AT; Bruder CE; Bohlooly-Y M; Gidlöf S; Oldfors A; Wibom R; Törnell J; Jacobs HT; Larsson NG
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All other publications

Editorial comment: ACTA OBSTETRICIA ET GYNECOLOGICA SCANDINAVICA. 2024;103(5):784-785
Task-shifting from healthcare staff to patients is necessary for the future
Gidlof S
Editorial comment: ACTA OBSTETRICIA ET GYNECOLOGICA SCANDINAVICA. 2023;102(10):1323-1328
Endometriosis and menopause-management strategies based on clinical scenarios
Jakson I; Hirschberg AL; Gidlof SB
Editorial comment: ACTA OBSTETRICIA ET GYNECOLOGICA SCANDINAVICA. 2022;101(6):562-563
Medical innovations are driven by controversies
Gidlof S; Acharya G
Conference publication: EUROPEAN JOURNAL OF OBSTETRICS AND GYNECOLOGY AND REPRODUCTIVE BIOLOGY. 2022;270:E94
Human endometrial mait cells are transiently tissue resident and respond to neisseria gonorrhoeae
Guterstam YC; Bister J; Strunz B; Dumitrescu B; Bhattarai KH; Ozenci V; Brannstrom M; Ivarsson M; Gidlof S; Bjorkstrom N
Editorial comment: ACTA OBSTETRICIA ET GYNECOLOGICA SCANDINAVICA. 2021;100(10):1755
Is the scalpel the greatest proof of the failure of medicine?
Gidlof S
Letter: ACTA OBSTETRICIA ET GYNECOLOGICA SCANDINAVICA. 2020;99(7):948-949
COVID-19 in pregnancy with comorbidities: More liberal testing strategy is needed
Gidlof S; Savchenko J; Brune T; Josefsson H
Editorial comment: ACTA OBSTETRICIA ET GYNECOLOGICA SCANDINAVICA. 2019;98(2):137-138
When will we stop encouraging awareness of fetal movements?
Gidlof S
Editorial comment: ACTA OBSTETRICIA ET GYNECOLOGICA SCANDINAVICA. 2017;96(6):621-622
When endometriosis is the barrier for fertility
Rudnicki M; Gemzell-Danielsson K; Gidlof S
Conference publication: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2017;86(4):302
MAIT cells accumulate in placental intervillous space and display a highly cytotoxic phenotype
Solders M; Gorchs L; Erkers T; Lundell A-C; Nava S; Gidlof S; Tiblad E; Magalhaes I; Kaipe H
Conference publication: GYNECOLOGICAL ENDOCRINOLOGY. 2016;32:79
Hepatic steatosis in polycystic ovary syndrome
Gidlof S; Skorpil M; Oberg E; Mitsell M; Jakson I; Ryden H; Tollet-Egnell P; Hirschberg A
Conference publication: GYNECOLOGICAL ENDOCRINOLOGY. 2016;32:46-47
Reproductive outcome in women with congenital adrenal hyperplasia - a population-based cohort study
Gidlof S; Nordenstrom A; Nordenskjold A; Frisen L; Butwicka A; Falhammar H; Hirschberg A
Conference publication: GYNECOLOGICAL ENDOCRINOLOGY. 2016;32:69
Insulin modulates in vitro decidualization of human endometrial stromal cells via transcriptional inhibition of Forkhead box protein O1 (FOXO1)
Ujvari D; Jakson I; Babayeva S; Salamon D; Rethi B; Gidloef S; Hirschberg AL
Editorial comment: ACTA OBSTETRICIA ET GYNECOLOGICA SCANDINAVICA. 2015;94:1-2
Use of progesterone in female reproduction: tradition and trends
Gidlof S
Letter: JAMA PEDIATRICS. 2014;168(10):971
Does Newborn Screening Have 100% Sensitivity to Detect Salt-Wasting Congenital Adrenal Hyperplasia? A Word of Caution Reply
Gidlof S; Nordenstrom A
Editorial comment: ACTA OBSTETRICIA ET GYNECOLOGICA SCANDINAVICA. 2014;93(8):725-726
Improving women's health locally and globally
Gidloef S
Thesis / dissertation: 2013
Congenital adrenal hyperplasia, cyp21a2 deficiency : clinical and physiological aspects of pregnancy, screening and growth
Gidlöf, Sebastian
Conference publication: HORMONE RESEARCH IN PAEDIATRICS. 2008;70:241
Androgen explosure does not increase prenatal or infant growth, as shown in congenital adrenal hyperplasia
Gidlof S; Hogling DE; Nordenstrom A
Conference publication: BIOCHIMICA ET BIOPHYSICA ACTA - BIOENERGETICS. 2004;1657:21
Creation of mtDNA mutator mice
Trifunovic A; Larsson NG; Wredenberg A; Falkenberg M; Spelbrink J; Rovio A; Bruder C; Bohlooly M; Gidlöf S; Oldfors A; Wibom R; Törnell J; Jacobs H

Employments

Affiliated to Research, Department of Clinical Science, Intervention and Technology, Karolinska Institutet, 2024-2026

Degrees and Education

Docent, Karolinska Institutet, 2023
Degree Of Doctor Of Philosophy, Department of Molecular Medicine and Surgery, Karolinska Institutet, 2013
University Medical Degree, Karolinska Institutet, 2008

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