Sara Svensson Akusjärvi

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About me

Postdoctoral researcher in the Ivan Zanoni lab at Boston Children's Hospital, Harvard Medical School and Anna Smed Sörensen lab at Karolinska Institutet.

Research focus on the IFN response during respiratory infections.

Articles

Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2023;120(37):e2304722120
Systems-level temporal immune- metabolic profile in Crimean-Congo hemorrhagic fever virus infection
Ambikan AT; Elaldi N; Akusjaervi SS; Bagci B; Pektas AN; Hewson R; Bagci G; Arasli M; Appelberg S; Mardinoglu A; Sood V; Vegvari A; Benfeitas R; Gupta S; Cetin I; Mirazimi A; Neogi U
Article: AIDS. 2023;37(7):1023-1033
Role of myeloid cells in system-level immunometabolic dysregulation during prolonged successful HIV-1 treatment
Svensson Akusjarvi S; Krishnan S; Ambikan AT; Mikaeloff F; Munusamy Ponnan S; Vesterbacka J; Lourda M; Nowak P; Sonnerborg A; Neogi U
Article: CURRENT HIV/AIDS REPORTS. 2023;20(2):42-50
Biological Aging in People Living with HIV on Successful Antiretroviral Therapy: Do They Age Faster?
Akusjaervi SS; Neogi U
Article: LIFE SCIENCE ALLIANCE. 2022;5(9):e202201405
Genome-scale metabolic models for natural and long-term drug-induced viral control in HIV infection
Ambikan AT; Svensson-Akusjarvi S; Krishnan S; Sperk M; Nowak P; Vesterbacka J; Sonnerborg A; Benfeitas R; Neogi U
Article: CELL SYSTEMS. 2022;13(8):665-681.e4
Multi-omics personalized network analyses highlight progressive disruption of central metabolism associated with COVID-19 severity
Ambikan AT; Yang H; Krishnan S; Akusjarvi SS; Gupta S; Lourda M; Sperk M; Arif M; Zhang C; Nordqvist H; Ponnan SM; Sonnerborg A; Treutiger CJ; O'Mahony L; Mardinoglu A; Benfeitas R; Neogi U
Article: ELIFE. 2022;11:e76071
Multi-omics insights into host-viral response and pathogenesis in Crimean-Congo hemorrhagic fever viruses for novel therapeutic target
Neogi U; Elaldi N; Appelberg S; Ambikan A; Kennedy E; Dowall S; Bagci BK; Gupta S; Rodriguez JE; Svensson-Akusjarvi S; Monteil V; Vegvari A; Benfeitas R; Banerjea A; Weber F; Hewson R; Mirazimi A
Article: COMMUNICATIONS BIOLOGY. 2022;5(1):357
Peripheral blood CD4⁺CCR6⁺ compartment differentiates HIV-1 infected or seropositive elite controllers from long-term successfully treated individuals
Svensson Akusjarvi S; Krishnan S; Jutte BB; Ambikan AT; Gupta S; Rodriguez JE; Vegvari A; Sperk M; Nowak P; Vesterbacka J; Svensson JP; Sonnerborg A; Neogi U
Article: ISCIENCE. 2022;25(1):103607
Integrative proteo-transcriptomic and immunophenotyping signatures of HIV-1 elite control phenotype: A cross-talk between glycolysis and HIF signaling
Akusjarvi SS; Ambikan AT; Krishnan S; Gupta S; Sperk M; Vegvari A; Mikaeloff F; Healy K; Vesterbacka J; Nowak P; Sonnerborg A; Neogi U
Article: COMMUNICATIONS BIOLOGY. 2022;5(1):27
Trans cohort metabolic reprogramming towards glutaminolysis in long-term successfully treated HIV-infection
Mikaeloff F; Akusjarvi SS; Ikomey GM; Krishnan S; Sperk M; Gupta S; Magdaleno GDV; Escos A; Lyonga E; Okomo MC; Tagne CT; Babu H; Lorson CL; Vegvari A; Banerjea AC; Kele J; Hanna LE; Singh K; de Magalhaes JP; Benfeitas R; Neogi U
Article: AGING. 2021;13(19):22732-22751
The central role of the glutamate metabolism in long-term antiretroviral treated HIV-infected individuals with metabolic syndrome
Gelpi M; Mikaeloff F; Knudsen AD; Benfeitas R; Krishnan S; Akusjarvi SS; Hogh J; Murray DD; Ullum H; Neogi U; Nielsen SD
Article: ISCIENCE. 2021;24(2):102111
Distinct lipid profile, low-level inflammation, and increased antioxidant defense signature in HIV-1 elite control status
Sperk M; Mikaeloff F; Svensson-Akusjarvi S; Krishnan S; Ponnan SM; Ambikan AT; Nowak P; Sonnerborg A; Neogi U
Article: MOLECULAR & CELLULAR PROTEOMICS. 2021;20:100159
Metabolic Perturbation Associated With COVID-19 Disease Severity and SARS-CoV-2 Replication
Krishnan S; Nordqvist H; Ambikan AT; Gupta S; Sperk M; Svensson-Akusjarvi S; Mikaeloff F; Benfeitas R; Saccon E; Ponnan SM; Rodriguez JE; Nikouyan N; Odeh A; Ahlen G; Asghar M; Sallberg M; Vesterbacka J; Nowak P; Vegvari A; Sonnerborg A; Treutiger CJ; Neogi U
Article: EMERGING MICROBES AND INFECTIONS. 2020;9(1):1748-1760
Dysregulation in Akt/mTOR/HIF-1 signaling identified by proteo-transcriptomics of SARS-CoV-2 infected cells
Appelberg S; Gupta S; Svensson Akusjarvi S; Ambikan AT; Mikaeloff F; Saccon E; Vegvari A; Benfeitas R; Sperk M; Stahlberg M; Krishnan S; Singh K; Penninger JM; Mirazimi A; Neogi U
Article: PLOS PATHOGENS. 2020;16(1):e1008264
Chromatin maturation of the HIV-1 provirus in primary resting CD4⁺ T cells
Lindqvist B; Akusjarvi SS; Sonnerborg A; Dimitriou M; Svensson JP
Article: FRONTIERS IN IMMUNOLOGY. 2019;10:1965
Systemic Inflammation and the Increased Risk of Inflamm-Aging and Age-Associated Diseases in People Living With HIV on Long Term Suppressive Antiretroviral Therapy
Babu H; Ambikan AT; Gabriel EE; Akusjarvi SS; Palaniappan AN; Sundaraj V; Mupanni NR; Sperk M; Cheedarla N; Sridhar R; Tripathy SP; Nowak P; Hanna LE; Neogi U
Article: FRONTIERS IN MICROBIOLOGY. 2018;9:2358
Characterization of Inducible Transcription and Translation-Competent HIV-1 Using the RNAscope ISH Technology at a Single-Cell Resolution
Zhang W; Akusjarvi SS; Sonnerborg A; Neogi U
Article: FRONTIERS IN PHARMACOLOGY. 2017;8:433
Phenotypic Screening Identifies Synergistically Acting Natural Product Enhancing the Performance of Biomaterial Based Wound Healing
Sivasubramanian S; Chandrasekar G; Akusjarvi SS; Thangam R; Sathuvan M; Kumar RBS; Hussein H; Vincent S; Madhan B; Gunasekaran P; Kitambi SS

All other publications

Thesis / dissertation: 2022
Immunometabolic reprogramming during suppressive HIV-1 infection
Svensson Akusjärvi, Sara
Review: DRUG DESIGN, DEVELOPMENT AND THERAPY. 2017;11:1957-1967
Cell and small animal models for phenotypic drug discovery
Szabo M; Akusjarvi SS; Saxena A; Liu J; Chandrasekar G; Kitambi SS

Employments

Postdoctoral Researcher, Department of Medicine, Karolinska Institutet, 2023-2025

Degrees and Education

Degree Of Doctor Of Philosophy, Department of Laboratory Medicine, Karolinska Institutet, 2022

About me

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