Samir Morsli
About me
Samir studied Biomedical Science at The University of Sheffield (UK), where he carried out research on asthma-associated proteins and their regulation of human mast cell function. He followed this with an MSc(Res) in Translational Oncology, which included a research project on developing an in vivo model of castration-resistant prostate cancer in zebrafish. In 2015, he carried out his PhD at The University of Sheffield (UK), supervised by Prof. Ilaria Bellantuono and Prof. Stephen Renshaw. During these four years he developed a novel tool to study cellular senescence in vivo by making a transgenic zebrafish for the gene p21 (cdkn1a) (Morsli et al., 2023). Following his PhD, he was awarded a grant from the MRC’s Proximity to Discovery Fund to test senolytics in the cdkn1a:GFP zebrafish model.
In 2021, he joined the lab of Dr Daniel Muñoz-Espín at The University of Cambridge to research the
- role of senescence in lung cancer development and progression, using the P16FDR mouse model (Haston et al., 2023). During this time, he also became the vice-president of the early career component of the International Cell Senescence Association (yICSA).
Finally, in 2024 he has joined the Pietrocola lab in 2024 as a senior postdoc at the Karolinska Institutet, further exploring the mechanisms underpinning senescence, cancer, and immunity.
Articles
- Journal article: NPJ AGING AND MECHANISMS OF DISEASE. 2024;10(1):53
- Journal article: ANGEWANDTE CHEMIE INTERNATIONAL EDITION. 2024;63(25):e202404885
- Journal article: CANCER CELL. 2023;41(7):1242-1260.e6
- Journal article: AGING CELL. 2023;22(6):e13835
- Journal article: MECHANISMS OF AGEING AND DEVELOPMENT. 2022;202:111618
- Journal article: MECHANISMS OF AGEING AND DEVELOPMENT. 2021;193:111391
Employments
- Postdoctoral Studies, Department of Cell and Molecular Biology, Karolinska Institutet, 2024-2026
- Postdoctoral Research Associate, Oncology, Oncology, The University of Cambridge, 2021-2024
Degrees and Education
- Doctor of Philosophy (PhD), Gerontology, Establishing a model of stress-induced senescence in zebrafish larvae, University of Sheffield, 2020
Committee work
- Vice president, Young International Cell Senescence Association (yICSA), https://www.cellsenescence.info/yicsa, 2023-
Conference/event participation
- Chair, GRS Biology of Aging, https://www.grc.org/biology-of-aging-grs-conference/2023/, 2023