Saedis Saevarsdottir

Publications
CV
Public outreach and news

Articles

Article: SCANDINAVIAN JOURNAL OF RHEUMATOLOGY. 2023;52(6):591-600
Evaluation of an individually tailored smoking-cessation intervention for patients with rheumatoid arthritis in an outpatient clinic
Karlsson M-L; Hertzberg-Nyquist K; Saevarsdottir S; Lundberg IE; Demmelmaier I; Pettersson S; Chatzidionysiou K
Article: RHEUMATOLOGY. 2023;62(6):2106-2112
The association between autoantibodies and risk for venous thromboembolic events among patients with rheumatoid arthritis
Westerlind H; Kastbom A; Ronnelid J; Hansson M; Alfredsson L; Mathsson-Alm L; Serre G; Cornillet M; Holmdahl R; Skriner K; Bang H; Klareskog L; Saevarsdottir S; Lundberg K; Gronwall C; Askling J
Article: RMD OPEN. 2022;8(2):e002700
Comorbidities and treatment patterns in early rheumatoid arthritis: a nationwide Swedish study
Tidblad L; Westerlind H; Delcoigne B; Askling J; Saevarsdottir S
Article: CLINICAL PHARMACOLOGY & THERAPEUTICS. 2022;112(4):836-845
Combined Conventional Synthetic Disease Modifying Therapy vs. Infliximab for Rheumatoid Arthritis: Emulating a Randomized Trial in Observational Data
Barbulescu A; Askling J; Saevarsdottir S; Kim SC; Frisell T
Article: ARTHRITIS RESEARCH & THERAPY. 2022;24(1):203
Neither low social support nor low decision latitude at work is associated with disease remission among patients with rheumatoid arthritis: results from the Swedish EIRA study
Hedenstierna L; Hedstrom AK; Klareskog L; Di Giuseppe D; Alfredsson L; Askling J; Ernestam S; Saevarsdottir S; Ljung L
Article: ARTHRITIS RESEARCH & THERAPY. 2022;24(1):185
Does persistence to methotrexate treatment in early rheumatoid arthritis have a familial component?
Sysojev AO; Frisell T; Delcoigne B; Saevarsdottir S; Askling J; Westerlind H
Article: ANNALS OF THE RHEUMATIC DISEASES. 2022;81(8):1085-1095
Multiomics analysis of rheumatoid arthritis yields sequence variants that have large effects on risk of the seropositive subset
Saevarsdottir S; Stefansdottir L; Sulem P; Thorleifsson G; Ferkingstad E; Rutsdottir G; Glintborg B; Westerlind H; Grondal G; Loft IC; Sorensen SB; Lie BA; Brink M; Arlestig L; Arnthorsson AO; Baecklund E; Banasik K; Bank S; Bjorkman LI; Ellingsen T; Erikstrup C; Frei O; Gjertsson I; Gudbjartsson DF; Gudjonsson SA; Halldorsson GH; Hendricks O; Hillert J; Hogdall E; Jacobsen S; Jensen DV; Jonsson H; Kastbom A; Kockum I; Kristensen S; Kristjansdottir H; Larsen MH; Linauskas A; Hauge E-M; Loft AG; Ludviksson BR; Lund SH; Markusson T; Masson G; Melsted P; Moore KHS; Munk H; Nielsen KR; Norddahl GL; Oddsson A; Olafsdottir TA; Olason PI; Olsson T; Ostrowski SR; Horslev-Petersen K; Rognvaldsson S; Sanner H; Silberberg GN; Stefansson H; Sorensen E; Sorensen IJ; Turesson C; Bergman T; Alfredsson L; Kvien TK; Brunak S; Steinsson K; Andersen V; Andreassen OA; Rantapaa-Dahlqvist S; Hetland ML; Klareskog L; Askling J; Padyukov L; Pedersen OB; Thorsteinsdottir U; Jonsdottir I; Stefansson K
Article: NATURE COMMUNICATIONS. 2022;13(1):1598
A genome-wide meta-analysis identifies 50 genetic loci associated with carpal tunnel syndrome.
Skuladottir AT; Bjornsdottir G; Ferkingstad E; Einarsson G; Stefansdottir L; Nawaz MS; Oddsson A; Olafsdottir TA; Saevarsdottir S; Walters GB; Magnusson SH; Bjornsdottir A; Sveinsson OA; Vikingsson A; Hansen TF; Jacobsen RL; Erikstrup C; Schwinn M; Brunak S; Banasik K; Ostrowski SR; Troelsen A; Henkel C; Pedersen OB; DBDS Genetic Consortium; Jonsdottir I; Gudbjartsson DF; Sulem P; Thorgeirsson TE; Stefansson H; Stefansson K
Article: RMD OPEN. 2022;8(1):e001800
Sleep problems in rheumatoid arthritis over 12 years from diagnosis: results from the Swedish EIRA study
Lyne L; Akerstedt T; Alfredsson L; Lehtonen T; Saevarsdottir S; Klareskog L; Westerlind H
Article: FRONTIERS IN IMMUNOLOGY. 2022;13:804822
Antibodies to a Citrullinated Porphyromonas gingivalis Epitope Are Increased in Early Rheumatoid Arthritis, and Can Be Produced by Gingival Tissue B Cells: Implications for a Bacterial Origin in RA Etiology
Sherina N; de Vries C; Kharlamova N; Sippl N; Jiang X; Brynedal B; Kindstedt E; Hansson M; Mathsson-Alm L; Israelsson L; Stalesen R; Saevarsdottir S; Holmdahl R; Hensvold A; Johannsen G; Eriksson K; Sallusto F; Catrina AI; Roennelid J; Groenwall C; Yucel-Lindberg T; Alfredsson L; Klareskog L; Piccoli L; Malmstroem V; Amara K; Lundberg K
Article: NATURE GENETICS. 2021;53(12):1712-1721
Large-scale integration of the plasma proteome with genetics and disease.
Ferkingstad E; Sulem P; Atlason BA; Sveinbjornsson G; Magnusson MI; Styrmisdottir EL; Gunnarsdottir K; Helgason A; Oddsson A; Halldorsson BV; Jensson BO; Zink F; Halldorsson GH; Masson G; Arnadottir GA; Katrinardottir H; Juliusson K; Magnusson MK; Magnusson OT; Fridriksdottir R; Saevarsdottir S; Gudjonsson SA; Stacey SN; Rognvaldsson S; Eiriksdottir T; Olafsdottir TA; Steinthorsdottir V; Tragante V; Ulfarsson MO; Stefansson H; Jonsdottir I; Holm H; Rafnar T; Melsted P; Saemundsdottir J; Norddahl GL; Lund SH; Gudbjartsson DF; Thorsteinsdottir U; Stefansson K
Article: ARTHRITIS & RHEUMATOLOGY. 2021;73(11):2025-2034
The CRTAC1 Protein in Plasma Is Associated With Osteoarthritis and Predicts Progression to Joint Replacement: A Large-Scale Proteomics Scan in Iceland
Styrkarsdottir U; Lund SH; Saevarsdottir S; Magnusson MI; Gunnarsdottir K; Norddahl GL; Frigge ML; Ivarsdottir EV; Bjornsdottir G; Holm H; Thorgeirsson G; Rafnar T; Jonsdottir I; Ingvarsson T; Jonsson H; Sulem P; Thorsteinsdottir U; Gudbjartsson D; Stefansson K
Article: COMMUNICATIONS BIOLOGY. 2021;4(1):1148
A genome-wide meta-analysis uncovers six sequence variants conferring risk of vertigo.
Skuladottir AT; Bjornsdottir G; Nawaz MS; Petersen H; Rognvaldsson S; Moore KHS; Olafsson PI; Magnusson SH; Bjornsdottir A; Sveinsson OA; Sigurdardottir GR; Saevarsdottir S; Ivarsdottir EV; Stefansdottir L; Gunnarsson B; Muhlestein JB; Knowlton KU; Jones DA; Nadauld LD; Hartmann AM; Rujescu D; Strupp M; Walters GB; Thorgeirsson TE; Jonsdottir I; Holm H; Thorleifsson G; Gudbjartsson DF; Sulem P; Stefansson H; Stefansson K
Article: COMMUNICATIONS BIOLOGY. 2021;4(1):1132
Genetic variants associated with platelet count are predictive of human disease and physiological markers.
Mikaelsdottir E; Thorleifsson G; Stefansdottir L; Halldorsson G; Sigurdsson JK; Lund SH; Tragante V; Melsted P; Rognvaldsson S; Norland K; Helgadottir A; Magnusson MK; Ragnarsson GB; Kristinsson SY; Reykdal S; Vidarsson B; Gudmundsdottir IJ; Olafsson I; Onundarson PT; Sigurdardottir O; Sigurdsson EL; Grondal G; Geirsson AJ; Geirsson G; Gudmundsson J; Holm H; Saevarsdottir S; Jonsdottir I; Thorgeirsson G; Gudbjartsson DF; Thorsteinsdottir U; Rafnar T; Stefansson K
Article: ARTHRITIS CARE & RESEARCH. 2021;73(9):1312-1321
Pain Over Two Years After Start of Biologic Versus Conventional Combination Treatment in Early Rheumatoid Arthritis: Results From a Swedish Randomized Controlled Trial
Olofsson T; Wallman JK; Joud A; Schelin MEC; Ernestam S; van Vollenhoven R; Saevarsdottir S; Lampa J
Article: ARTHRITIS RESEARCH & THERAPY. 2021;23(1):209
Is tea consumption associated with reduction of risk of rheumatoid arthritis? A Swedish case-control study
Westerlind H; Palmqvist I; Saevarsdottir S; Alfredsson L; Klareskog L; Di Giuseppe D
Article: RHEUMATOLOGY. 2021;60(8):3760-3769
Comorbidities at diagnosis of rheumatoid arthritis: a population-based case-control study
Tidblad L; Westerlind H; Delcoigne B; Askling J; Saevarsdottir S
Article: CLINICAL AND EXPERIMENTAL RHEUMATOLOGY. 2021;39(4):879-882
Rheumatoid arthritis autoantibodies and their association with age and sex
Pertsinidou E; Manivel VA; Westerlind H; Klareskog L; Alfredsson L; Mathsson-Alm L; Hansson M; Saevatsdottir S; Askling J; Ronnelid J
Article: RHEUMATOLOGY. 2021;60(5):2217-2222
Mortality over 14 years in MTX-refractory patients randomized to a strategy of addition of infliximab or sulfasalazine and hydroxychloroquine
Miller H; Wallman JK; Petersson IF; Saevarsdottir S; Soderlng J; Ernestam S; Askling J; van Vollenhoven R; Neovius M
Article: SCANDINAVIAN JOURNAL OF RHEUMATOLOGY. 2021;50(3):178-182
Social stressors and risk of rheumatoid arthritis and their relationship to known modifiable risk factors: results from the Swedish EIRA study
Hedenstierna L; Opava CH; Askling J; Jiang X; Ernestam S; Alfredsson L; Klareskog L; Saevarsdottir S
Article: ARTHRITIS RESEARCH & THERAPY. 2021;23(1):1
Validation of the adjusted multi-biomarker disease activity score as a prognostic test for radiographic progression in rheumatoid arthritis: a combined analysis of multiple studies
Curtis JR; Weinblatt ME; Shadick NA; Brahe CH; Ostergaard M; Hetland ML; Saevarsdottir S; Horton M; Mabey B; Flake DDII; Ben-Shachar R; Sasso EH; Huizinga TW
Article: FRONTIERS IN IMMUNOLOGY. 2021;12:627986
A Comprehensive Evaluation of the Relationship Between Different IgG and IgA Anti-Modified Protein Autoantibodies in Rheumatoid Arthritis
Gronwall C; Liljefors L; Bang H; Hensvold AH; Hansson M; Mathsson-Alm L; Israelsson L; Joshua V; Svard A; Stalesen R; Titcombe PJ; Steen J; Piccoli L; Sherina N; Clavel C; Svenungsson E; Gunnarsson I; Saevarsdottir S; Kastbom A; Serre G; Alfredsson L; Malmstrom V; Ronnelid J; Catrina AI; Lundberg K; Klareskog L
Article: NATURE COMMUNICATIONS. 2020;11(1):5976
Genetic predisposition to hypertension is associated with preeclampsia in European and Central Asian women
Steinthorsdottir V; McGinnis R; Williams NO; Stefansdottir L; Thorleifsson G; Shooter S; Fadista J; Sigurdsson JK; Auro KM; Berezina G; Borges M-C; Bumpstead S; Bybjerg-Grauholm J; Colgiu I; Dolby VA; Dudbridge F; Engel SM; Franklin CS; Frigge ML; Frisbaek Y; Geirsson RT; Geller F; Gretarsdottir S; Gudbjartsson DF; Harmon Q; Hougaard DM; Hegay T; Helgadottir A; Hjartardottir S; Jaeaeskelaeinen T; Johannsdottir H; Jonsdottir I; Juliusdottir T; Kalsheker N; Kasimov A; Kemp JP; Kivinen K; Klungsoyr K; Lee WK; Melbye M; Miedzybrodska Z; Moffett A; Najmutdinova D; Nishanova F; Olafsdottir T; Perola M; Pipkin FB; Poston L; Prescott G; Saevarsdottir S; Salimbayeva D; Scaife PJ; Skotte L; Staines-Urias E; Stefansson OA; Sorensen KM; Thomsen LCV; Tragante V; Trogstad L; Simpson NAB; Laivuori H; Morgan L; Aripova T; Casas JP; Dominiczak AF; Walker JJ; Thorsteinsdottir U; Iversen A-C; Feenstra B; Lawlor DA; Boyd HA; Magnus P; Laivuori H; Zakhidova N; Svyatova G; Stefansson K; Morgan L; Laivuori H; Heinonen S; Kajantie E; Kere J; Kivinen K; Pouta A; Morgan L; Pipkin FB; Kalsheker N; Walker JJ; Macphail S; Kilby M; Habiba M; Williamson C; O'Shaughnessy K; O'Brien S; Cameron A; Redman CWG; Farrall M; Caulfield M; Dominiczak AF
Article: SEMINARS IN ARTHRITIS AND RHEUMATISM. 2020;50(5):1101-1108
Association of serum anti-centromere protein F antibodies with clinical response to infliximab in patients with rheumatoid arthritis: A prospective study
Lourido L; Ruiz-Romero C; Picchi F; Diz-Rosales N; Vilaboa-Galan S; Fernandez-Lopez C; Pinto Tasende JA; Perez-Pampin E; Regueiro C; Mera-Varela A; Gonzalez A; Hambardzumyan K; Saevarsdottir S; Nilsson P; Blanco FJ
Article: ARTHRITIS & RHEUMATOLOGY. 2020;72(10):1658-1667
Anti-Citrullinated Protein Antibody Specificities, Rheumatoid Factor Isotypes, and Incident Cardiovascular Events in Patients With Rheumatoid Arthritis
Westerlind H; Ronnelid J; Hansson M; Alfredsson L; Mathsson-Alm L; Serre G; Cornillet M; Holmdahl R; Jakobsson P-J; Skriner K; Klareskog L; Saevarsdottir S; Askling J
Article: NATURE. 2020;584(7822):619-623
FLT3 stop mutation increases FLT3 ligand level and risk of autoimmune thyroid disease
Saevarsdottir S; Olafsdottir TA; Ivarsdottir EV; Halldorsson GH; Gunnarsdottir K; Sigurdsson A; Johannesson A; Sigurdsson JK; Juliusdottir T; Lund SH; Arnthorsson AO; Styrmisdottir EL; Gudmundsson J; Grondal GM; Steinsson K; Alfredsson L; Askling J; Benediktsson R; Bjarnason R; Geirsson AJ; Gudbjornsson B; Gudjonsson H; Hjaltason H; Hreidarsson AB; Klareskog L; Kockum I; Kristjansdottir H; Love TJ; Ludviksson BR; Olsson T; Onundarson PT; Orvar KB; Padyukov L; Sigurgeirsson B; Tragante V; Bjarnadottir K; Rafnar T; Masson G; Sulem P; Gudbjartsson DF; Melsted P; Thorleifsson G; Norddahl GL; Thorsteinsdottir U; Jonsdottir I; Stefansson K
Article: RHEUMATOLOGY. 2020;59(8):1842-1852
An updated matrix to predict rapid radiographic progression of early rheumatoid arthritis patients: pooled analyses from several databases
Vanier A; Smolen JS; Allaart CF; Van Vollenhoven R; Verschueren P; Vastesaeger N; Saevarsdottir S; Visser K; Aletaha D; Combe B; Fautrel B
Article: ARTHRITIS RESEARCH & THERAPY. 2020;22(1):170
Presence of autoantibodies in "seronegative" rheumatoid arthritis associates with classical risk factors and high disease activity
Reed E; Hedstrom AK; Hansson M; Mathsson-Alm L; Brynedal B; Saevarsdottir S; Cornillet M; Jakobsson P-J; Holmdahl R; Skriner K; Serre G; Alfredsson L; Ronnelid J; Lundberg K
Article: RMD OPEN. 2020;6(2):e001282
Does autoimmune thyroid disease affects rheumatoid arthritis disease activity or response to methotrexate?
Waldenlind K; Delcoigne B; Saevarsdottir S; Askling J
Article: ARTHRITIS RESEARCH & THERAPY. 2020;22(1):15
Abatacept in rheumatoid arthritis: survival on drug, clinical outcomes, and their predictors-data from a large national quality register
Cagnotto G; Willim M; Nilsson J-A; Compagno M; Jacobsson LTH; Saevarsdottir S; Turesson C
Article: FRONTIERS IN IMMUNOLOGY. 2020;11:1365
Drug Tolerant Anti-drug Antibody Assay for Infliximab Treatment in Clinical Practice Identifies Positive Cases Earlier
Kharlamova N; Hermanrud C; Dunn N; Ryner M; Hambardzumyan K; Pomiano NV; Marits P; Gjertsson I; Saevarsdottir S; Pullerits R; Fogdell-Hahn A
Article: SCANDINAVIAN JOURNAL OF RHEUMATOLOGY. 2019;48(5):362-366
Association of female sex and positive rheumatoid factor with low serum infliximab and anti-drug antibodies, related to treatment failure in early rheumatoid arthritis: results from the SWEFOT trial population
Hambardzumyan K; Hermanrud C; Marits P; Vivar N; Ernestam S; Wallman JK; van Vollenhoven RF; Fogdell-Hahn A; Saevarsdottir S
Article: CURRENT MEDICAL RESEARCH AND OPINION. 2019;35(9):1483-1493
Predicting risk for radiographic damage in rheumatoid arthritis: comparative analysis of the multi-biomarker disease activity score and conventional measures of disease activity in multiple studies
Curtis JR; Brahe CH; Ostergaard M; Hetland ML; Hambardzumyan K; Saevarsdottir S; Wang X; Flake DDII; Sasso EH; Huizinga TW
Article: ANNALS OF THE RHEUMATIC DISEASES. 2019;78(8):1055-1061
Association of response to TNF inhibitors in rheumatoid arthritis with quantitative trait loci for CD40 and CD39
Spiliopoulou A; Colombo M; Plant D; Nair N; Cui J; Coenen MJH; Ikari K; Yamanaka H; Saevarsdottir S; Padyukov L; Bridges SLJ; Kimberly RP; Okada Y; van Riel PLCM; Wolbink G; van der Horst-Bruinsma IE; de Vries N; Tak PP; Ohmura K; Canhao H; Guchelaar H-J; Huizinga TWJ; Criswell LA; Raychaudhuri S; Weinblatt ME; Wilson AG; Mariette X; Isaacs JD; Morgan AW; Pitzalis C; Barton A; McKeigue P
Article: SEMINARS IN ARTHRITIS AND RHEUMATISM. 2019;48(6):967-975
Incidence and risk factors for adalimumab and infliximab anti-drug antibodies in rheumatoid arthritis: A European retrospective multicohort analysis
Quistrebert J; Hassler S; Bachelet D; Mbogning C; Musters A; Tak PP; Wijbrandts CA; Herenius M; Bergstra SA; Akdemir G; Johannesson M; Combe B; Fautrel B; Chollet-Martin S; Gleizes A; Donnellan N; Deisenhammer F; Davidson J; Hincelin-Mery A; Donnes P; Fogdell-Hahn A; De Vries N; Huizinga T; Abugessaisa I; Saevarsdottir S; Hacein-Bey-Abina S; Pallardy M; Broet P; Mariette X
Article: JOURNAL OF RHEUMATOLOGY. 2019;46(6):555-563
Serum Biomarkers for Prediction of Response to Methotrexate Monotherapy in Early Rheumatoid Arthritis: Results from the SWEFOT Trial
Hambardzumyan K; Bolce RJ; Wallman JK; van Vollenhoven RF; Saevarsdottir S
Article: JOURNAL OF CLINICAL MEDICINE. 2019;8(5):E630-630
Periodontal Health and Oral Microbiota in Patients with Rheumatoid Arthritis
Eriksson K; Fei G; Lundmark A; Benchimol D; Lee L; Hu YOO; Kats A; Saevarsdottir S; Catrina AI; Klinge B; Andersson AF; Klareskog L; Lundberg K; Jansson L; Yucel-Lindberg T
Article: SCANDINAVIAN JOURNAL OF RHEUMATOLOGY. 2019;48(1):17-23
Smoking and response to rituximab in rheumatoid arthritis: results from an international European collaboration
Chatzidionysiou K; Lukina G; Gabay C; Hetland ML; Hauge EM; Pavelka K; Nordstrom D; Canhao H; Tomsic M; Rotar Z; Lie E; Kvien TK; van Vollenhoven RF; Saevarsdottir S
Article: RMD OPEN. 2019;5(2):e000978
Occupational exposure to asbestos and silica and risk of developing rheumatoid arthritis: findings from a Swedish population-based case-control study
Ilar A; Klareskog L; Saevarsdottir S; Wiebert P; Askling J; Gustaysson P; Alfredsson L
Article: JAMA NETWORK OPEN. 2018;1(6):e183567
Risk of Thyroxine-Treated Autoimmune Thyroid Disease Associated With Disease Onset in Patients With Rheumatoid Arthritis
Waldenlind K; Saevarsdottir S; Bengtsson C; Askling J
Article: ANNALS OF THE RHEUMATIC DISEASES. 2017;76(11):1845-1852
Oral contraceptives, breastfeeding and the risk of developing rheumatoid arthritis: results from the Swedish EIRA study
Orellana C; Saevarsdottir S; Klareskog L; Karlson EW; Alfredsson L; Bengtsson C
Article: ANNALS OF THE RHEUMATIC DISEASES. 2017;76(9):1607-1613
A single nucleotide polymorphism in the NCF1 gene leading to reduced oxidative burst is associated with systemic lupus erythematosus
Olsson LM; Johansson AC; Gullstrand B; Jonsen A; Saevarsdottir S; Ronnblom L; Leonard D; Wettero J; Sjowall C; Svenungsson E; Gunnarsson I; Bengtsson AA; Holmdahl R
Article: ANNALS OF THE RHEUMATIC DISEASES. 2017;76(9):1529-1536
Anticollagen type II antibodies are associated with an acute onset rheumatoid arthritis phenotype and prognosticate lower degree of inflammation during 5 years follow-up
Manivel VA; Mullazehi M; Padyukov L; Westerlind H; Klareskog L; Alfredsson L; Saevarsdottir S; Ronnelid J
Article: ARTHRITIS & RHEUMATOLOGY. 2017;69(5):953-963
A Multi-Biomarker Disease Activity Score and the Choice of Second-Line Therapy in Early Rheumatoid Arthritis After Methotrexate Failure
Hambardzumyan K; Saevarsdottir S; Forslind K; Petersson IF; Wallman JK; Ernestam S; Bolce RJ; van Vollenhoven RF
Article: RMD OPEN. 2017;3(2):e000458
Obesity is a strong predictor of worse clinical outcomes and treatment responses in early rheumatoid arthritis: results from the SWEFOT trial.
Levitsky A; Brismar K; Hafström I; Hambardzumyan K; Lourdudoss C; van Vollenhoven RF; Saevarsdottir S
Article: ARTHRITIS RESEARCH & THERAPY. 2016;18(1):288
A genetic risk score composed of rheumatoid arthritis risk alleles, HLA-DRB1 haplotypes, and response to TNFi therapy - results from a Swedish cohort study
Jiang X; Askling J; Saevarsdottir S; Padyukov L; Alfredsson L; Viatte S; Frisell T
Article: JOURNAL OF PHYSICAL ACTIVITY & HEALTH. 2016;13(11):1236-1242
Correlates of Leisure Time Physical Inactivity in a Scandinavian Population: A Basis for Interventions
Bonn SE; Alfredsson L; Saevarsdottir S; Schelin MEC
Article: NATURE COMMUNICATIONS. 2016;7:12460
Crowdsourced assessment of common genetic contribution to predicting anti-TNF treatment response in rheumatoid arthritis
Sieberts SK; Zhu F; Garcia-Garcia J; Stahl E; Pratap A; Pandey G; Pappas D; Aguilar D; Anton B; Bonet J; Eksi R; Fornes O; Guney E; Li H; Marin MA; Panwar B; Planas-Iglesias J; Poglayen D; Cui J; Falcao AO; Suver C; Hoff B; Balagurusamy VSK; Dillenberger D; Neto EC; Norman T; Aittokallio T; Ammad-ud-din M; Azencott C-A; Bellon V; Boeva V; Bunte K; Chheda H; Cheng L; Corander J; Dumontier M; Goldenberg A; Gopalacharyulu P; Hajiloo M; Hidru D; Jaiswal A; Kaski S; Khalfaoui B; Khan SA; Kramer ER; Marttinen P; Mezlini AM; Molparia B; Pirinen M; Saarela J; Samwald M; Stoven V; Tang H; Tang J; Torkamani A; Vert J-P; Wang B; Wang T; Wennerberg K; Wineinger NE; Xiao G; Xie Y; Yeung R; Zhan X; Zhao C; Greenberg J; Kremer J; Michaud K; Barton A; Coenen M; Mariette X; Miceli C; Shadick N; Weinblatt M; de Vries N; Tak PP; Gerlag D; Huizinga TWJ; Kurreeman F; Allaart CF; Bridges SLJ; Criswell L; Moreland L; Klareskog L; Saevarsdottir S; Padyukov L; Gregersen PK; Friend S; Plenge R; Stolovitzky G; Oliva B; Guan Y; Mangravite LM
Article: ARTHRITIS CARE & RESEARCH. 2016;68(8):1061-1068
Remaining Pain in Early Rheumatoid Arthritis Patients Treated With Methotrexate
Altawil R; Saevarsdottir S; Wedren S; Alfredsson L; Klareskog L; Lampa J
Article: ANNALS OF THE RHEUMATIC DISEASES. 2016;75(6):1120-1125
Does a family history of RA influence the clinical presentation and treatment response in RA?
Frisell T; Saevarsdottir S; Askling J
Article: ANNALS OF THE RHEUMATIC DISEASES. 2016;75(2):356-361
Changes in the anticitrullinated peptide antibody response in relation to therapeutic outcome in early rheumatoid arthritis: results from the SWEFOT trial
Kastbom A; Forslind K; Ernestam S; Geborek P; Karlsson JA; Petersson IF; Saevarsdottir S; Klareskog L; van Vollenhoven RF; Lundberg K
Article: RMD OPEN. 2016;2(1):e000197
Association of a multibiomarker disease activity score at multiple time-points with radiographic progression in rheumatoid arthritis: results from the SWEFOT trial.
Hambardzumyan K; Bolce RJ; Saevarsdottir S; Forslind K; Wallman JK; Cruickshank SE; Sasso EH; Chernoff D; van Vollenhoven RF
Article: ARTHRITIS RESEARCH & THERAPY. 2015;17:358
Parity influences the severity of ACPA-negative early rheumatoid arthritis: a cohort study based on the Swedish EIRA material
Pikwer M; Orellana C; Kallberg H; Pikwer A; Turesson C; Klareskog L; Alfredsson L; Saevarsdottir S; Bengtsson C
Article: ARTHRITIS RESEARCH & THERAPY. 2015;17:317
Higher education is associated with a better rheumatoid arthritis outcome concerning for pain and function but not disease activity: results from the EIRA cohort and Swedish rheumatology register
Jiang X; Sandberg MEC; Saevarsdottir S; Klareskog L; Alfredsson L; Bengtsson C
Article: ARTHRITIS & RHEUMATOLOGY. 2015;67(11):2855-2860
Enhancement of Patient Recruitment in Rheumatoid Arthritis Clinical Trials Using a Multi-Biomarker Disease Activity Score as an Inclusion Criterion
van Vollenhoven RF; Bolce R; Hambardzumyan K; Saevarsdottir S; Forslind K; Petersson IF; Sasso EH; Hwang CC; Segurado OG; Geborek P
Article: ARTHRITIS RESEARCH & THERAPY. 2015;17(1):239
Serum RANKL levels associate with anti- citrullinated protein antibodies in early untreated rheumatoid arthritis and are modulated following methotrexate
Hensvold AH; Joshua V; Li W; Larkin M; Qureshi F; Israelsson L; Padyukov L; Lundberg K; Defranoux N; Saevarsdottir S; Catrina AI
Article: ANNALS OF THE RHEUMATIC DISEASES. 2015;74(8):1509-1514
Current smoking status is a strong predictor of radiographic progression in early rheumatoid arthritis: results from the SWEFOT trial
Saevarsdottir S; Rezaei H; Geborek P; Petersson I; Ernestam S; Albertsson K; Forslind K; van Vollenhoven RF
Article: ANNALS OF THE RHEUMATIC DISEASES. 2015;74(6):1102-1109
Pretreatment multi-biomarker disease activity score and radiographic progression in early RA: results from the SWEFOT trial
Hambardzumyan K; Bolce R; Saevarsdottir S; Cruickshank SE; Sasso EH; Chernoff D; Forslind K; Petersson IF; Geborek P; van Vollenhoven RF
Article: EUROPEAN JOURNAL OF EPIDEMIOLOGY. 2015;30(5):449-457
Postmenopausal hormone therapy and the risk of rheumatoid arthritis: results from the Swedish EIRA population-based case-control study
Orellana C; Saevarsdottir S; Klareskog L; Karlson EW; Alfredsson L; Bengtsson C
Article: ANNALS OF THE RHEUMATIC DISEASES. 2015;74(5):904-907
Recent infections are associated with decreased risk of rheumatoid arthritis: a population-based case-control study
Sandberg MEC; Bengtsson C; Klareskog L; Alfredsson L; Saevarsdottir S
Article: ANNALS OF THE RHEUMATIC DISEASES. 2015;74(3):579-586
Identification of anticitrullinated protein antibody reactivities in a subset of anti-CCP-negative rheumatoid arthritis: association with cigarette smoking and HLA-DRB1 'shared epitope' alleles
Wagner CA; Sokolove J; Lahey LJ; Bengtsson C; Saevarsdottir S; Alfredsson L; Delanoy M; Lindstrom TM; Walker RP; Bromberg R; Chandra PE; Binder SR; Klareskog L; Robinson WH
Article: ANNALS OF THE RHEUMATIC DISEASES. 2014;73(11):2029-2033
Overweight decreases the chance of achieving good response and low disease activity in early rheumatoid arthritis
Sandberg MEC; Bengtsson C; Kallberg H; Wesley A; Klareskog L; Alfredsson L; Saevarsdottir S
Article: ANNALS OF THE RHEUMATIC DISEASES. 2014;73(8):1541-1544
Patients with regular physical activity before onset of rheumatoid arthritis present with milder disease
Sandberg MEC; Wedren S; Klareskog L; Lundberg IE; Opava CH; Alfredsson L; Saevarsdottir S
Article: ANNALS OF THE RHEUMATIC DISEASES. 2014;73(6):1096-1100
Thyroxin substitution and the risk of developing rheumatoid arthritis; results from the Swedish population-based EIRA study
Bengtsson C; Padyukov L; Kallberg H; Saevarsdottir S
Article: ARTHRITIS CARE & RESEARCH. 2014;66(6):844-851
Association Between Life Events and Rheumatoid Arthritis: Results From a Population-Based Case-Control Study
Wesley A; Bengtsson C; Skillgate E; Saevarsdottir S; Theorell T; Holmqvist M; Klareskog L; Alfredsson L; Wedren S
Article: PLOS ONE. 2014;9(9):e104382
Accelerating Translational Research by Clinically Driven Development of an Informatics Platform-A Case Study
Abugessaisa I; Saevarsdottir S; Tsipras G; Lindblad S; Sandin C; Nikamo P; Stahle M; Malmstrom V; Klareskog L; Tegner J
Article: ANNALS OF THE RHEUMATIC DISEASES. 2013;72(8):1375-1381
Genome-wide association analysis of anti-TNF drug response in patients with rheumatoid arthritis
Mirkov MU; Cui J; Vermeulen SH; Stahl EA; Toonen EJM; Makkinje RR; Lee AT; Huizinga TWJ; Allaart R; Barton A; Mariette X; Miceli CR; Criswell LA; Tak PP; de Vries N; Saevarsdottir S; Padyukov L; Bridges SL; van Schaardenburg D-J; Jansen TL; Dutmer EAJ; de laar MAFJV; Barrera P; Radstake TRDJ; van Riel PLCM; Scheffer H; Franke B; Brunner HG; Plenge RM; Gregersen PK; Guchelaar H-J; Coenen MJH
Article: BMC MUSCULOSKELETAL DISORDERS. 2013;14:79
Evaluation of hand bone loss by digital X-ray radiogrammetry as a complement to clinical and radiographic assessment in early rheumatoid arthritis: results from the SWEFOT trial
Rezaei H; Saevarsdottir S; Geborek P; Petersson IF; van Vollenhoven RF; Forslind K
Article: PLOS GENETICS. 2013;9(3):e1003394
Genome-Wide Association Study and Gene Expression Analysis Identifies CD84 as a Predictor of Response to Etanercept Therapy in Rheumatoid Arthritis
Cui J; Stahl EA; Saevarsdottir S; Miceli C; Diogo D; Trynka G; Raj T; Mirkov MU; Canhao H; Ikari K; Terao C; Okada Y; Wedren S; Askling J; Yamanaka H; Momohara S; Taniguchi A; Ohmura K; Matsuda F; Mimori T; Gupta N; Kuchroo M; Morgan AW; Isaacs JD; Wilson AG; Hyrich KL; Herenius M; Doorenspleet ME; Tak P-P; Crusius JBA; van der Horst-Bruinsma IE; Wolbink GJ; van Riel PLCM; van de Laar M; Guchelaar H-J; Shadick NA; Allaart CF; Huizinga TWJ; Toes REM; Kimberly RP; Bridges SLJ; Criswell LA; Moreland LW; Fonseca JE; de Vries N; Stranger BE; De Jager PL; Raychaudhuri S; Weinblatt ME; Gregersen PK; Mariette X; Barton A; Padyukov L; Coenen MJH; Karlson EW; Plenge RM
Article: ARTHRITIS & RHEUMATOLOGY. 2012;64(7):2078-2084
Very high levels of anti-citrullinated protein antibodies are associated with HLA-DRB1*15 non-shared epitope allele in patients with rheumatoid arthritis
Laki J; Lundstrom E; Snir O; Ronnelid J; Ganji I; Catrina AI; Bengtsson C; Saevarsdottir S; Wick MC; Alfredsson L; Klareskog L; Padyukov L
Article: ANNALS OF THE RHEUMATIC DISEASES. 2012;71(2):186-191
In early rheumatoid arthritis, patients with a good initial response to methotrexate have excellent 2-year clinical outcomes, but radiological progression is not fully prevented: data from the methotrexate responders population in the SWEFOT trial
Rezaei H; Saevarsdottir S; Forslind K; Albertsson K; Wallin H; Bratt J; Ernestam S; Geborek P; Petersson IF; van Vollenhoven RF
Article: BMJ OPEN. 2012;2(5):e001524
Influence of FCGR3A genotype on the therapeutic response to rituximab in rheumatoid arthritis: an observational cohort study
Kastbom A; Coster L; Arlestig L; Chatzidionysiou A; van Vollenhoven RF; Padyukov L; Rantapaa-Dahlqvist S; Saevarsdottir S
Article: PHARMACOGENETICS AND GENOMICS. 2012;22(1):1-9
Patterns of interaction between genetic and nongenetic attributes and methotrexate efficacy in rheumatoid arthritis
Dervieux T; Wessels JAM; Kremer JM; Padyukov L; Seddighzadeh M; Saevarsdottir S; van Vollenhoven RF; Klareskog L; Huizinga TW; Guchelaar H-J
Article: ARTHRITIS RESEARCH & THERAPY. 2011;13(2):R65
Mannan Binding Lectin (MBL) genotypes coding for high MBL serum levels are associated with rheumatoid factor negative rheumatoid arthritis in never smokers
Saevarsdottir S; Ding B; Steinsson K; Grondal G; Valdimarsson H; Alfredsson L; Klareskog L; Padyukov L
Article: ANNALS OF THE RHEUMATIC DISEASES. 2011;70(3):469-475
Predictors of response to methotrexate in early DMARD naive rheumatoid arthritis: results from the initial open-label phase of the SWEFOT trial
Saevarsdottir S; Wallin H; Seddighzadeh M; Ernestam SA; Geborek P; Petersson IF; Bratt J; van Vollenhoven RF
Article: ARTHRITIS & RHEUMATOLOGY. 2011;63(1):26-36
Patients With Early Rheumatoid Arthritis Who Smoke Are Less Likely to Respond to Treatment With Methotrexate and Tumor Necrosis Factor Inhibitors Observations From the Epidemiological Investigation of Rheumatoid Arthritis and the Swedish Rheumatology Register Cohorts
Saevarsdottir S; Wedren S; Seddighzadeh M; Bengtsson C; Wesley A; Lindblad S; Askling J; Alfredsson L; Klareskog L
Article: ARTHRITIS & RHEUMATOLOGY. 2010;62(7):1849-1861
Rheumatoid Arthritis Risk Allele PTPRC Is Also Associated With Response to Anti-Tumor Necrosis Factor α Therapy
Cui J; Saevarsdottir S; Thomson B; Padyukov L; van der Helm-van Mil AHM; Nititham J; Hughes LB; de Vries N; Raychaudhuri S; Alfredsson L; Askling J; Wedren S; Ding B; Guiducci C; Wolbink GJ; Crusius JBA; van der Horst-Bruinsma IE; Herenius M; Weinblatt ME; Shadick NA; Worthington J; Batliwalla F; Kern M; Morgan AW; Wilson AG; Isaacs JD; Hyrich K; Seldin MF; Moreland LW; Behrens TW; Allaart CF; Criswell LA; Huizinga TWJ; Tak PP; Bridges SLJ; Toes REM; Barton A; Klareskog L; Gregersen PK; Karlson EW; Plenge RM
Article: ARTHRITIS & RHEUMATOLOGY. 2008;58(12):3865-3872
Association of Three Systemic Lupus Erythematosus Susceptibility Factors, PD-1.3A, C4AQ0, and Low Levels of Mannan-Binding Lectin, With Autoimmune Manifestations in Icelandic Multicase Systemic Lupus Erythematosus Families
Kristjansdottir H; Saevarsdottir S; Grondal G; Alarcon-Riquelme ME; Erlendsson K; Valdimarsson H; Steinsson K
Article: CLINICAL INFECTIOUS DISEASES. 2008;47(4):510-516
Low serum mannose-binding lectin level increases the risk of death due to pneumococcal infection
Eisen DP; Dean MM; Boermeester MA; Fidler KJ; Gordon AC; Kronborg G; Kun JFJ; Lau YL; Payeras A; Valdimarsson H; Brett SJ; Ip WKE; Mila J; Peters MJ; Saevarsdottir S; van Till JWO; Hinds CJ; McBryde ES
Article: JOURNAL OF RHEUMATOLOGY. 2007;34(8):1692-1695
Patients with rheumatoid arthritis have higher levels of mannan-binding lectin than their first-degree relatives and unrelated controls
Saevarsdottir S; Steinsson K; Grondal G; Valdimarsson H
Article: CLINICAL AND EXPERIMENTAL IMMUNOLOGY. 2007;148(2):248-253
Mannan-binding lectin may facilitate the clearance of circulating immune complexes--implications from a study on C2-deficient individuals.
Saevarsdottir S; Steinsson K; Ludviksson BR; Grondal G; Valdimarsson H
Article: ANNALS OF THE RHEUMATIC DISEASES. 2006;65(11):1462-1467
Mannan-binding lectin and complement C4A in Icelandic multicase families with systemic lupus erythematosus.
Saevarsdottir S; Kristjansdottir H; Grondal G; Vikingsdottir T; Steinsson K; Valdimarsson H
Article: JOURNAL OF EXPERIMENTAL MEDICINE. 2005;201(1):117-125
Mannan binding lectin as an adjunct to risk assessment for myocardial infarction in individuals with enhanced risk.
Saevarsdottir S; Oskarsson OO; Aspelund T; Eiriksdottir G; Vikingsdottir T; Gudnason V; Valdimarsson H
Article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2004;59(1):97-102
Human plasma-derived mannose-binding lectin: a phase I safety and pharmacokinetic study.
Valdimarsson H; Vikingsdottir T; Bang P; Saevarsdottir S; Gudjonsson JE; Oskarsson O; Christiansen M; Blou L; Laursen I; Koch C
Article: JOURNAL OF RHEUMATOLOGY. 2001;28(4):728-734
Low mannose binding lectin predicts poor prognosis in patients with early rheumatoid arthritis. A prospective study.
Saevarsdottir S; Vikingsdottir T; Vikingsson A; Manfredsdottir V; Geirsson AJ; Valdimarsson H
Show more

All other publications

Letter: JOINT BONE SPINE. 2022;89(4):105357
Established risk loci for systemic lupus erythematosus at NCF2, STAT4, TNPO3, IRF5 and ITGAM associate with distinct clinical manifestations: A Danish genome-wide association study.
Leffers HCB; Westergaard D; Saevarsdottir S; Jonsdottir I; Pedersen OB; DBDS genomic consortium; Troldborg A; Voss A; Kristensen S; Lindhardsen J; Kumar P; Linauskas A; Juul L; Krogh NS; Deleuran B; Dreyer L; Schwinn M; Thørner LW; Hindhede L; Erikstrup C; Ullum H; Brunak S; Stefansson K; Banasik K; Jacobsen S
Letter: CLINICAL AND EXPERIMENTAL RHEUMATOLOGY. 2020;38(5):1029-1030
Occupational physical workload and development of anti-collagen type II antibodies in rheumatoid arthritis: results from the Swedish EIRA population-based case-control study
Zeng P; Pertsinidou E; Brynedal B; Manivel VA; Klareskog L; Mullazehi M; Saevarsdottir S; Bengtsson C; Alfredsson L; Ronnelid J
Review: JOURNAL OF INTERNAL MEDICINE. 2020;287(5):514-533
The importance of differences; On environment and its interactions with genes and immunity in the causation of rheumatoid arthritis
Klareskog L; Ronnelid J; Saevarsdottir S; Padyukov L; Alfredsson L
Letter: ARTHRITIS & RHEUMATOLOGY. 2018;70(12):2096-2097
Anti-Carbamylated Protein Antibodies and Higher Baseline Disease Activity in Rheumatoid Arthritis-A Replication Study in Three Cohorts: Comment on the Article by Truchetet et al
Derksen VFAM; Westerlind H; Saevarsdottir S; Ajeganova S; Trouw LA; Huizinga TWJ; van der Helm-van Mil AHM; Knevel R; van der Woude D
Review: NATURE REVIEWS RHEUMATOLOGY. 2016;12(6):335-343
Family history of rheumatoid arthritis: an old concept with new developments
Frisell T; Saevarsdottir S; Askling J
Letter: ANNALS OF THE RHEUMATIC DISEASES. 2014;73(12):e79
Response to: 'Obesity and comorbidity are independently associated with a failure to achieve remission in patients with established rheumatoid arthritis' by Ellerby et al
Sandberg MEC; Bengtsson C; Kallberg H; Wesley A; Klareskog L; Alfredsson L; Saevarsdottir S
Review: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2004;60(1-2):23-29
The potential role of mannan-binding lectin in the clearance of self-components including immune complexes.
Saevarsdottir S; Vikingsdottir T; Valdimarsson H

Articles

All other publications

Employments

Degrees and Education

News from KI

Events from KI