Rui Sun

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About me

I am a PhD candidate at Karolinska Institutet.

My research interest is about B cell biology in the context of virus infection and tumour. More specifically, I isolate and look into the B cells in severe COVID-19 and HBV-associated B cell lymphoma. Currently we are also working on tonsil organoid to recapitulate the germinal center responses upon infection/ antigen stimulation.

Articles

Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2024;121(3):e2315354120
Conversion of monoclonal IgG to dimeric and secretory IgA restores neutralizing ability and prevents Infection of Omicron lineages
Marcotte H; Cao Y; Zuo F; Simonelli L; Sammartino JC; Pedotti M; Sun R; Cassaniti I; Hagbom M; Piralla A; Yang J; Du L; Percivalle E; Bertoglio F; Schubert M; Abolhassani H; Sherina N; Guerra C; Borte S; Rezaei N; Kumagai-Braesch M; Xue Y; Su C; Yan Q; He P; Groenwall C; Klareskog L; Calzolai L; Cavalli A; Wang Q; Robbiani DF; Hust M; Shi Z; Feng L; Svensson L; Chen L; Bao L; Baldanti F; Xiao J; Qin C; Hammarstrom L; Yang X; Varani L; Xie XS; Pan-Hammarstrom Q
Article: NATURE COMMUNICATIONS. 2023;14(1):6527
Design, structure and plasma binding of ancestral β-CoV scaffold antigens
Hueting D; Schriever K; Sun R; Vlachiotis S; Zuo F; Du L; Persson H; Hofstrom C; Ohlin M; Wallden K; Buggert M; Hammarstrom L; Marcotte H; Pan-Hammarstroem Q; Andrell J; Syren P-O
Article: ISCIENCE. 2023;26(4):106562
19n01, a broadly neutralizing antibody against omicron BA.1, BA.2, BA.4/5, and other SARS-CoV-2 variants of concern
Garcia-Vega M; Melgoza-Gonzalez EA; Hernandez-Valenzuela S; Hinojosa-Trujillo D; Resendiz-Sandoval M; Llamas-Covarrubias MA; Loza-Lopez M; Valenzuela O; Soto-Gaxiola A; Hernandez-Onate MA; Mata-Haro V; Cassaniti I; Sammartino JC; Ferrari A; Simonelli L; Pedotti M; Sun R; Zuo F; Baldanti F; Varani L; Marcotte H; Pan-Hammarstrom Q; Hernandez J
Journal article: BIOMEDICINES. 2021;9(6):640
A Rational Designed Novel Bispecific Antibody for the Treatment of GBM.
Sun R; Zhou Y; Han L; Pan Z; Chen J; Zong H; Bian Y; Jiang H; Zhang B; Zhu J

All other publications

Editorial comment: THE LANCET INFECTIOUS DISEASES. 2024;24(1):e7-e9
Neutralisation activity of mucosal IgA against XBB sublineages and BA.2.86
Zuo F; Cao Y; Sun R; Yisimayi A; Du L; Bertoglio F; Schubert M; Guerra C; Cavalli A; Hust M; Robbiani DF; Abolhassani H; Xie XS; Hammarstroem L; Marcotte H; Pan-Hammarstroem Q
Review: EXPERT REVIEW OF CLINICAL IMMUNOLOGY. 2023;19(7):771-784
Cellular mechanisms and clinical applications for phenocopies of inborn errors of immunity: infectious susceptibility due to cytokine autoantibodies
Sun R; Wang Y; Abolhassani H
Preprint: BIORXIV. 2023
Conversion of monoclonal IgG to dimeric and secretory IgA restores neutralizing ability and prevents infection of Omicron lineages
Marcotte H; Cao Y; Zuo F; Simonelli L; Sammartino JC; Pedotti M; Sun R; Cassaniti I; Hagbom M; Piralla A; Yang J; Du L; Percivalle E; Bertoglio F; Schubert M; Abolhassani H; Sherina N; Guerra C; Borte S; Razaei N; Kumagai-Braesch M; Xue Y; Grönwall C; Klareskog L; Calzolai L; Cavalli A; Wang Q; Robbiani D; Hust M; Shi Z; Feng L; Svensson L; Chen L; Bao L; Baldanti F; Qin C; Xiao J; Hammarström L; Yang XL; Varani L; Xie XS; Pan-Hammarström Q
Letter: THE LANCET REGIONAL HEALTH. WESTERN PACIFIC. 2023;33:100762
Heterologous inactivated virus/mRNA vaccination response to BF.7, BQ.1.1, and XBB.1
Zuo F; Sun R; Abolhassani H; Du L; Wang Y; Vlachiotis S; Bertoglio F; Schubert M; Rezaei N; Chavoshzadeh Z; Guerra C; Cavalli A; Andrell J; Kumagai-Braesch M; Xue Y; Cao Y; Hust M; Robbiani DF; Xie XS; Hammarstrom L; Marcotte H; Pan-Hammarstrom Q
Preprint: MEDRXIV. 2022
Heterologous immunization with inactivated vaccine followed by mRNA booster elicits strong humoral and cellular immune responses against the SARS-CoV-2 Omicron variant
Zuo F; Abolhassani H; Du L; Piralla A; Bertoglio F; de Campos-Mata L; Wan H; Schubert M; Wang Y; Sun R; Cassaniti I; Vlachiotis S; Kumagai-Braesch M; Andréll J; Zhang Z; Xue Y; Wenzel EV; Calzolai L; Varani L; Rezaei N; Chavoshzadeh Z; Baldanti F; Hust M; Hammarström L; Marcotte H; Pan-Hammarström Q

Grants

Immunity and antibody therapy against emerging SARS-CoV-2 variants
Karolinska Institutet Virus Research

About me

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