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Publications

Characterization and target genes of nine human PRD-like homeobox domain genes expressed exclusively in early embryos
Madissoon E, Jouhilahti Em, Vesterlund L, Töhönen V, Krjutškov K, Petropoulos S, et al
Scientific reports 2016;6():28995-

Corrigendum: Characterization and target genes of nine human PRD-like homeobox domain genes expressed exclusively in early embryos
Madissoon E, Jouhilahti Em, Vesterlund L, Töhönen V, Krjutškov K, Petropoulos S, et al
Scientific reports 2016;6():32053-

The human PRD-like homeobox gene LEUTX has a central role in embryo genome activation
Jouhilahti Em, Madissoon E, Vesterlund L, Töhönen V, Krjutškov K, Plaza Reyes A, et al
Development (Cambridge, England) 2016;143(19):3459-3469

Ebf1 heterozygosity results in increased DNA damage in pro-B cells and their synergistic transformation by Pax5 haploinsufficiency
Prasad Ma, Ungerbäck J, Åhsberg J, Somasundaram R, Strid T, Larsson M, et al
Blood 2015;125(26):4052-9

Loss of Murine FOXO3 in Cells of the Myeloid Lineage Enhances Myelopoiesis but Protects from K/BxN-Serum Transfer-Induced Arthritis
Kang H, Corr M, Mansson R, Welinder E, Hedrick Sm, Stone El
PloS one 2015;10(5):e0126728-

Splice-correction strategies for treatment of X-linked agammaglobulinemia
Bestas B, Turunen Jj, Blomberg Ke, Wang Q, Månsson R, El Andaloussi S, et al
Current allergy and asthma reports 2015;15(3):510-

Targets for Ibrutinib Beyond B Cell Malignancies
Berglöf A, Hamasy A, Meinke S, Palma M, Krstic A, Månsson R, et al
Scandinavian journal of immunology 2015;82(3):208-17

The chromatin remodeler Brg1 activates enhancer repertoires to establish B cell identity and modulate cell growth
Bossen C, Murre Cs, Chang An, Mansson R, Rodewald Hr, Murre C
Nature immunology 2015;16(7):775-84

Variants in ELL2 influencing immunoglobulin levels associate with multiple myeloma
Swaminathan B, Thorleifsson G, Jöud M, Ali M, Johnsson E, Ajore R, et al
Nature communications 2015;6():7213-

Splice-correcting oligonucleotides restore BTK function in X-linked agammaglobulinemia model
Bestas B, Moreno Pm, Blomberg Ke, Mohammad Dk, Saleh Af, Sutlu T, et al
The Journal of clinical investigation 2014;124(9):4067-81

CCAAT/enhancer binding protein alpha (C/EBP alpha)-induced transdifferentiation of pre-B cells into macrophages involves no overt retrodifferentiation (vol 108, 17016, 2011)
Di Tullio A, Thien Pvm, Schubert A, Castellano G, Mansson R, Graf T
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 2012;109(27):11053-11053

Chromatin Topology and the Regulation of Antigen Receptor Assembly
Bossen C, Mansson R, Murre C, Paul We
ANNUAL REVIEW OF IMMUNOLOGY, VOL 30 2012;:337-56

Global changes in the nuclear positioning of genes and intra- and interdomain genomic interactions that orchestrate B cell fate
Lin Yc, Benner C, Mansson R, Heinz S, Miyazaki K, Miyazaki M, et al
Nature immunology 2012;13(12):1196-204

Positive intergenic feedback circuitry, involving EBF1 and FOXO1, orchestrates B-cell fate
Mansson R, Welinder E, Ahsberg J, Lin Yc, Benner C, Glass Ck, et al
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 2012;109(51):21028-33

A dose-dependent role for EBF1 in repressing non-B-cell-specific genes
Lukin K, Fields S, Guerrettaz L, Straign D, Rodriguez V, Zandi S, et al
EUROPEAN JOURNAL OF IMMUNOLOGY 2011;41(6):1787-93

CCAAT/enhancer binding protein alpha (C/EBP alpha)-induced transdifferentiation of pre-B cells into macrophages involves no overt retrodifferentiation
Di Tullio A, Thien Pvm, Schubert A, Mansson R, Graf T
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 2011;108(41):17016-21

IL-7 mediates Ebf-1-dependent lineage restriction in early lymphoid progenitors
Tsapogas P, Zandi S, Ahsberg J, Zetterblad J, Welinder E, Jonsson Ji, et al
BLOOD 2011;118(5):1283-90

The transcription factors E2A and HEB act in concert to induce the expression of FOXO1 in the common lymphoid progenitor
Welinder E, Mansson R, Mercer Em, Bryder D, Sigvardsson M, Murre C
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 2011;108(42):17402-7

A global network of transcription factors, involving E2A, EBF1 and Foxo1, that orchestrates B cell fate
Lin Yc, Jhunjhunwala S, Benner C, Heinz S, Welinder E, Mansson R, et al
NATURE IMMUNOLOGY 2010;11(7):635-43

Genomics based analysis of interactions between developing B-lymphocytes and stromal cells reveal complex interactions and two-way communication
Zetterblad J, Qian H, Zandi S, Mansson R, Lagergren A, Hansson F, et al
BMC GENOMICS 2010;:108-

Interleukin-7-induced Stat-5 Acts in Synergy with Flt-3 Signaling to Stimulate Expansion of Hematopoietic Progenitor Cells
Ahsberg J, Tsapogas P, Qian H, Zetterblad J, Zandi S, Mansson R, et al
JOURNAL OF BIOLOGICAL CHEMISTRY 2010;285(47):36275-84

Single-cell analysis of the common lymphoid progenitor compartment reveals functional and molecular heterogeneity
Mansson R, Zandi S, Welinder E, Tsapogas P, Sakaguchi N, Bryder D, et al
BLOOD 2010;115(13):2601-9

Hematopoietic Stem Cell Expansion Precedes the Generation of Committed Myeloid Leukemia-initiating Cells in C/EBP alpha Mutant AML
Bereshchenko O, Mancini E, Moore S, Bilbao D, Mansson R, Luc S, et al
CANCER CELL 2009;16(5):390-400

B-lineage commitment prior to surface expression of B220 and CD19 on hematopoietic progenitor cells
Mansson R, Zandi S, Anderson K, Martensson Il, Jacobsen Sew, Bryder D, et al
BLOOD 2008;112(4):1048-55

E2A proteins promote development of lymphoid-primed multipotent progenitors
Dias S, Mansson R, Gurbuxani S, Sigvardsson M, Kee Bl
IMMUNITY 2008;29(2):217-27

EBF1 is essential for B-Lineage priming and establishment of a transcription factor network in common lymphoid progenitors
Zandi S, Mansson R, Tsapogas P, Zetterblad J, Bryder D, Sigvardsson M
JOURNAL OF IMMUNOLOGY 2008;181(5):3364-72

Exit of pediatric pre-B acute lymphoblastic leukaemia cells from the bone marrow to the peripheral blood is not associated with cell maturation or alterations in gene expression
Hansson F, Toporski J, Mansson R, Johansson B, Noren-nystrom U, Jacobsen Sew, et al
MOLECULAR CANCER 2008;:67-

Modeling of C/EBP alpha mutant acute myeloid leukemia reveals a common expression signature of committed myeloid leukemia-initiating cells
Kirstetter P, Schuster Mb, Bereshchenko O, Moore S, Dvinge H, Kurz E, et al
CANCER CELL 2008;13(4):299-310

Molecular profiling reveals distinct functional attributes of CD1d-restricted natural killer (NK) T cell subsets
Rolf J, Berntman E, Stenstrom M, Smith Emk, Mansson R, Stenstad H, et al
MOLECULAR IMMUNOLOGY 2008;45(9):2607-20

Critical role of FLT3 ligand in IL-7 receptor-independent T lymphopoiesis and regulation of lymphoid-primed multipotent progenitors
Sitnicka E, Buza-vidas N, Ahlenius H, Cilio Cm, Gekas C, Nygren Jm, et al
BLOOD 2007;110(8):2955-64

Critical role of thrombopoietin in maintaining adult quiescent hematopoietic stem cells
Qian H, Buza-vidas N, Hyland Cd, Jensen Ct, Antonchuk J, Mansson R, et al
CELL STEM CELL 2007;1(6):671-84

Ectopic expression of PAX5 promotes maintenance of biphenotypic myeloid progenitors coexpressing myeloid and B-cell lineage-associated genes
Anderson K, Rusterholz C, Mansson R, Jensen Ct, Bacos K, Zandi S, et al
BLOOD 2007;109(9):3697-705

Elucidation of the phenotypic, functional, and molecular topography of a myeloerythroid progenitor cell hierarchy
Pronk Cjh, Rossi Dj, Mansson R, Attema Jl, Norddahl Gl, Chan Ckf, et al
CELL STEM CELL 2007;1(4):428-42

Molecular evidence for hierarchical transcriptional lineage priming in fetal and adult stem cells and multipotent progenitors
Mansson R, Hultquist A, Luc S, Yang L, Anderson K, Kharazi S, et al
IMMUNITY 2007;26(4):407-19

The CD53 and CEACAM-1 genes are genetic targets for early B cell factor
Mansson R, Lagergren A, Hansson F, Smith E, Sigvardsson M
EUROPEAN JOURNAL OF IMMUNOLOGY 2007;37(5):1365-76

The Cxcl12, Periostin, and Ccl9 genes are direct targets for early B-cell factor in OP-9 stroma cells
Lagergren A, Mansson R, Zetterblad J, Smith E, Basta B, Bryder D, et al
JOURNAL OF BIOLOGICAL CHEMISTRY 2007;282(19):14454-62

The molecular signature of MDS stem cells supports a stem-cell origin of 5q - myelodysplastic syndromes
Nilsson L, Eden P, Olsson E, Mansson R, Astrand-grundstrom I, Strombeck B, et al
BLOOD 2007;110(8):3005-14

Cytokines regulate postnatal hematopoietic stem cell expansion: opposing roles of thrombopoietin and LNK
Buza-vidas N, Antonchuk J, Qian H, Mansson R, Luc S, Zandi S, et al
GENES & DEVELOPMENT 2006;20(15):2018-23

Gene expression analysis suggests that EBF-1 and PPAR gamma 2 induce adipogenesis of NIH-3T3 cells with similar efficiency and kinetics
Akerblad P, Mansson R, Lagergren A, Westerlund S, Basta B, Lind U, et al
PHYSIOLOGICAL GENOMICS 2005;23(2):206-16

Identification of Flt3(+) lympho-myeloid stem cells lacking erythro-megakaryocytic potential: A revised road map for adult blood lineage commitment
Adolfsson J, Mansson R, Buza-vidas N, Hultquist A, Liuba K, Jensen Ct, et al
CELL 2005;121(2):295-306

Identification of Lin(-)Sca1(+)kit(+)CD34(+)Flt(3-) short-term hematopoietic stem cells capable of rapidly reconstituting and rescuing myeloablated transplant recipients
Yang Lp, Bryder D, Adolfsson J, Nygren J, Mansson R, Sigvardsson M, et al
BLOOD 2005;105(7):2717-23

Predictive screening for regulators of conserved functional gene modules (gene batteries) in mammals
Nelander S, Larsson E, Kristiansson E, Mansson R, Nerman O, Sigvardsson M, et al
BMC GENOMICS 2005;:68-

Pearson correlation analysis of microarray data allows for the identification of genetic targets for early B-cell factor
Mansson R, Tsapogas P, Akerlund M, Lagergren A, Gisler R, Sigvardsson M
JOURNAL OF BIOLOGICAL CHEMISTRY 2004;279(17):17905-13

RNA analysis of B cell lines arrested at defined stages of differentiation allows for an approximation of gene expression patterns during B cell development
Tsapogas P, Breslin T, Bilke S, Lagergren A, Mansson R, Liberg D, et al
JOURNAL OF LEUKOCYTE BIOLOGY 2003;74(1):102-10

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