Rajan Kumar Pandey

About me
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About me

Postdoctoral researcher working on tolerogenic vaccine development against Rheumatoid Arthritis. I am a proficient Biochemist whose areas of expertise span rodent handling, cell culture, microbiological techniques, protein production, monoclonal antibody production, and bioinformatics. Holding both a Ph.D. in Biochemistry and a gold medal in M.Sc., I have amassed extensive knowledge and experience throughout my career. My background includes notable contributions to drug development and tolerogenic vaccine development, and I hold certification in the handling of mice models through the completion of the FELASA course.

Research

Vaccine development, Protein Biochemistry, Animal study

Teaching

Working as guest teacher a Karolinska Institute (Need basis)

Articles

Article: VIRULENCE. 2024;15(1):2303853

Gut-brain axis interplay via STAT3 pathway: Implications of Helicobacter pylori derived secretome on inflammation and Alzheimer's disease.

Kandpal M; Baral B; Varshney N; Jain AK; Chatterji D; Meena AK; Pandey RK; Jha HC
Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 2024;54(4):e2350659

Fcgr2b and Fcgr3 are the major genetic factors for cartilage antibody-induced arthritis, overriding the effect of Hc encoding complement C5.

Xu Z; Moreno-Giró À; Zhao D; Krämer A; Pandey RK; Xu B; Lundström SL; Holmdahl R
Article: GENES. 2024;15(4):426

Investigating the Influence of ANTXR2 Gene Mutations on Protective Antigen Binding for Heightened Anthrax Resistance.

Archana CA; Sekar YS; Suresh KP; Subramaniam S; Sagar N; Rani S; Anandakumar J; Pandey RK; Barman NN; Patil SS
Article: JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS. 2023;41(24):15682-15690

Elucidating the process of SNPs identification in non-reference genome crops.

Sudan J; Sharma S; Salgotra RK; Pandey RK; Neelam D; Singh R
Article: BMC BIOINFORMATICS. 2023;24(1):358

Designing and development of multi-epitope chimeric vaccine against Helicobacter pylori by exploring its entire immunogenic epitopes: an immunoinformatic approach.

Keshri AK; Kaur R; Rawat SS; Arora N; Pandey RK; Kumbhar BV; Mishra A; Tripathi S; Prasad A
Article: JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS. 2023;:1-11

Comprehensive examination on codon usage bias pattern of the Bovine Ephemeral fever virus.

Rani S; Mamathashree MN; Bharthi I U; Patil SS; Krishnamoorthy P; Shueb M; Pandey RK; Suresh KP
Article: CANCER CELL INTERNATIONAL. 2023;23(1):150

Macrophage's role in solid tumors: two edges of a sword.

Jahandideh A; Yarizadeh M; Noei-Khesht Masjedi M; Fatehnejad M; Jahandideh R; Soheili R; Eslami Y; Zokaei M; Ahmadvand A; Ghalamkarpour N; Kumar Pandey R; Nabi Afjadi M; Payandeh Z
Article: VACCINES. 2023;11(7):1182

Designing a Multi-Epitope Subunit Vaccine against VP1 Major Coat Protein of JC Polyomavirus.

Kanse S; Khandelwal M; Pandey RK; Khokhar M; Desai N; Kumbhar BV
Article: EXPERIMENTAL PARASITOLOGY. 2022;236-237:108250

Febrifugine dihydrochloride as a new oral chemotherapeutic agent against visceral leishmaniasis infection.

Pandey RK; Ojha R; Devender M; Sebastian P; Namdeo M; Kumbhar BV; Sundar S; Maurya R; Prajapati VK
Article: JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS. 2021;39(11):4051-4065

Immunoglobulin interface redesigning to enhance lebrikizumab mediated immunomodulation of IL-13 hyper-response.

Sharma V; Chouhan P; Pandey RK; Ojha R; Aathmanathan VS; Krishnan M; Prajapati VK
Journal article: INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES. 2020;101:477

Exploring sand fly salivary proteins to design multiepitope subunit vaccine to fight against visceral leishmaniasis

Pandey R; Prajapati VK
Article: INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES. 2020;156:548-557

Vaccinomics strategy to concoct a promising subunit vaccine for visceral leishmaniasis targeting sandfly and leishmania antigens.

Ojha R; Pandey RK; Prajapati VK
Article: INFECTION GENETICS AND EVOLUTION. 2020;82:104282

Immunoselective algorithm to devise multi-epitope subunit vaccine fighting against human cytomegalovirus infection.

Pandey RK; Ojha R; Dipti K; Kumar R; Prajapati VK
Article: ACS OMEGA. 2019;4(8):13069-13079

Strategic Development of a Next-Generation Multi-Epitope Vaccine To Prevent Nipah Virus Zoonotic Infection.

Ojha R; Pareek A; Pandey RK; Prusty D; Prajapati VK
Article: JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS. 2019;37(9):2381-2393

Exploratory algorithm to devise multi-epitope subunit vaccine by investigating Leishmania donovani membrane proteins.

Khatoon N; Pandey RK; Ojha R; Aathmanathan VS; Krishnan M; Prajapati VK
Article: JOURNAL OF CELLULAR PHYSIOLOGY. 2019;234(6):8717-8726

Combinatorial screening algorithm to engineer multiepitope subunit vaccine targeting human T-lymphotropic virus-1 infection.

Pandey RK; Ojha R; Chatterjee N; Upadhyay N; Mishra A; Prajapati VK
Article: INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES. 2019;122:1203-1211

Vaccination and immunization strategies to design Aedes aegypti salivary protein based subunit vaccine tackling Flavivirus infection.

Pandey RK; Dahiya S; Mahita J; Sowdhamini R; Prajapati VK
Article: JOURNAL OF CELLULAR BIOCHEMISTRY. 2019;120(2):1141-1155

Exploring sand fly salivary proteins to design multiepitope subunit vaccine to fight against visceral leishmaniasis.

Pandey RK; Prajapati VK
Article: EXPERIMENTAL PARASITOLOGY. 2018;194:67-78

Anti-infective activities of 11 plants species used in traditional medicine in Malaysia.

Nor Azman NS; Hossan MS; Nissapatorn V; Uthaipibull C; Prommana P; Jin KT; Rahmatullah M; Mahboob T; Raju CS; Jindal HM; Hazra B; Mohd Abd Razak MR; Prajapati VK; Pandey RK; Aminudin N; Shaari K; Ismail NH; Butler MS; Zarubaev VV; Wiart C
Article: JOURNAL OF CELLULAR BIOCHEMISTRY. 2018;119(9):7631-7642

Designing B- and T-cell multi-epitope based subunit vaccine using immunoinformatics approach to control Zika virus infection.

Kumar Pandey R; Ojha R; Mishra A; Kumar Prajapati V
Article: INFECTION GENETICS AND EVOLUTION. 2018;63:5-12

Chemical system biology based molecular interactions to identify inhibitors against Q151M mutant of HIV-1 reverse transcriptase.

Pandey RK; Sharma D; Ojha R; Bhatt TK; Prajapati VK
Article: VACCINE. 2018;36(30):4555-4565

Development of multi-epitope driven subunit vaccine in secretory and membrane protein of Plasmodium falciparum to convey protection against malaria infection.

Pandey RK; Ali M; Ojha R; Bhatt TK; Prajapati VK
Article: INFECTION GENETICS AND EVOLUTION. 2018;61:4-15

Excavating chikungunya genome to design B and T cell multi-epitope subunit vaccine using comprehensive immunoinformatics approach to control chikungunya infection.

Narula A; Pandey RK; Khatoon N; Mishra A; Prajapati VK
Article: VACCINE. 2018;36(17):2262-2272

Immunoinformatics approaches to design a novel multi-epitope subunit vaccine against HIV infection.

Pandey RK; Ojha R; Aathmanathan VS; Krishnan M; Prajapati VK
Article: SCIENTIFIC REPORTS. 2018;8(1):1125

Novel Immunoinformatics Approaches to Design Multi-epitope Subunit Vaccine for Malaria by Investigating Anopheles Salivary Protein.

Pandey RK; Bhatt TK; Prajapati VK
Article: COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING. 2017;20(8):734-746

Molecular Docking and Molecular Dynamics Simulation Based Approach to Explore the Dual Inhibitor Against HIV-1 Reverse Transcriptase and Integrase.

Chander S; Pandey RK; Penta A; Choudhary BS; Sharma M; Malik R; Prajapati VK; Murugesan S
Article: SCIENTIFIC REPORTS. 2017;7(1):9232

Exploring dengue genome to construct a multi-epitope based subunit vaccine by utilizing immunoinformatics approach to battle against dengue infection.

Ali M; Pandey RK; Khatoon N; Narula A; Mishra A; Prajapati VK
Article: SCIENTIFIC REPORTS. 2017;7(1):8285

Exploring Leishmania secretory proteins to design B and T cell multi-epitope subunit vaccine using immunoinformatics approach.

Khatoon N; Pandey RK; Prajapati VK
Article: JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS. 2017;35(4):791-804

Exploring dual inhibitory role of febrifugine analogues against Plasmodium utilizing structure-based virtual screening and molecular dynamic simulation.

Pandey RK; Narula A; Naskar M; Srivastava S; Verma P; Malik R; Shah P; Prajapati VK
Article: JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS. 2017;35(1):141-158

Febrifugine analogues as Leishmania donovani trypanothione reductase inhibitors: binding energy analysis assisted by molecular docking, ADMET and molecular dynamics simulation.

Pandey RK; Kumbhar BV; Srivastava S; Malik R; Sundar S; Kunwar A; Prajapati VK
Article: JOURNAL OF RECEPTORS AND SIGNAL TRANSDUCTION. 2017;37(1):60-70

Structure-based virtual screening, molecular docking, ADMET and molecular simulations to develop benzoxaborole analogs as potential inhibitor against Leishmania donovani trypanothione reductase.

Pandey RK; Kumbhar BV; Sundar S; Kunwar A; Prajapati VK
Article: FRONTIERS IN IMMUNOLOGY. 2017;8:107

Perturbed microRNA Expression by Mycobacterium tuberculosis Promotes Macrophage Polarization Leading to Pro-survival Foam Cell.

Ahluwalia PK; Pandey RK; Sehajpal PK; Prajapati VK
Article: COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING. 2016;19(10):813-823

Molecular Modeling and Virtual Screening Approach to Discover Potential Antileishmanial Inhibitors Against Ornithine Decarboxylase.

Pandey RK; Prajapati P; Goyal S; Grover A; Prajapati VK
Article: BIOMEDICINE & PHARMACOTHERAPY. 2016;83:141-152

High-throughput virtual screening and quantum mechanics approach to develop imipramine analogues as leads against trypanothione reductase of leishmania.

Pandey RK; Verma P; Sharma D; Bhatt TK; Sundar S; Prajapati VK
Journal article: ZEITSCHRIFT FUR GESUNDHEITSWISSENSCHAFTEN. 2016;24(2):83-89

Epidemiological investigation of a jaundice outbreak in Kishangarh, Rajasthan, India, 2014

Pandey RK; Prajapati P; Sharma T; Mandal CC; Prajapati VK
Journal article: INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES. 2016;45:374-375

MicroRNA mediated immune regulation of T helper cell differentiation and plasticity during visceral leishmaniasis infection: A computational approach

Pandey R; Prajapati VK; Sundar S
Article: JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS. 2015;33(12):2541-2553

Developing imidazole analogues as potential inhibitor for Leishmania donovani trypanothione reductase: virtual screening, molecular docking, dynamics and ADMET approach.

Pandey RK; Sharma D; Bhatt TK; Sundar S; Prajapati VK
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All other publications

Review: ACS INFECTIOUS DISEASES. 2024;10(3):827-844

Extracellular Vesicles in Malaria: Shedding Light on Pathogenic Depths.

Dey S; Mohapatra S; Khokhar M; Hassan S; Pandey RK
Book chapter: ADVANCES IN PROTEIN CHEMISTRY AND STRUCTURAL BIOLOGY, VOL 123: TRANSPORT PROTEINS. 2024;p. 91-156

Recent advances in CAR T-cell engineering using synthetic biology: Paving the way for next-generation cancer treatment.

Dey S; Devender M; Rani S; Pandey RK
Review: ACS CHEMICAL NEUROSCIENCE. 2023;14(17):2968-2980

Epigallocatechin Gallate: A Multifaceted Molecule for Neurological Disorders and Neurotropic Viral Infections.

Rani A; Saini V; Patra P; Prashar T; Pandey RK; Mishra A; Jha HC
Review: ARCHIVES OF MICROBIOLOGY. 2023;205(7):262

Comprehensive insight into altered host cell-signaling cascades upon Helicobacter pylori and Epstein-Barr virus infections in cancer.

Kashyap D; Rele S; Bagde PH; Saini V; Chatterjee D; Jain AK; Pandey RK; Jha HC
Review: PATHOGENS. 2023;12(5):635

Mechanism of Immune Evasion in Mosquito-Borne Diseases.

Bhattacharjee S; Ghosh D; Saha R; Sarkar R; Kumar S; Khokhar M; Pandey RK
Review: METABOLITES. 2022;12(11):1064

Dysbiosis of Gut Microbiota from the Perspective of the Gut-Brain Axis: Role in the Provocation of Neurological Disorders.

Kandpal M; Indari O; Baral B; Jakhmola S; Tiwari D; Bhandari V; Pandey RK; Bala K; Sonawane A; Jha HC
Book chapter: COLON CANCER DIAGNOSIS AND THERAPY. 2021;p. 73-90

Recent Therapeutic Strategies for the Treatment of Colon Cancer

Sharma V; Chouhan P; Pandey RK; Prajapati VK
Book chapter: FRONTIERS IN PROTEIN STRUCTURE, FUNCTION, AND DYNAMICS. 2020;p. 57-70

Wet-Lab Approaches to Determine Three-Dimensional Structures of Proteins

Pandey RK; Ojha R; Prajapati VK
Book chapter: NANOTECHNOLOGY BASED APPROACHES FOR TUBERCULOSIS TREATMENT. 2020;p. 75-90

Chapter 5 Vaccine delivery systems against tuberculosis

Ojha R; Pandey RK; Prajapati VK
Review: JOURNAL OF CELLULAR PHYSIOLOGY. 2019;234(2):1030-1043

Emerging role of circulating microRNA in the diagnosis of human infectious diseases.

Ojha R; Nandani R; Pandey RK; Mishra A; Prajapati VK
Review: INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES. 2018;107(Pt A):1278-1293

Molecular and immunological toxic effects of nanoparticles.

Pandey RK; Prajapati VK
Book chapter: DRUG DESIGN: PRINCIPLES AND APPLICATIONS. 2017;p. 69-88

Recent Advances in the Chemotherapy of Visceral Leishmaniasis

Prajapati VK; Pandey RK
Review: FRONTIERS IN MICROBIOLOGY. 2016;7:1274

Circulating MicroRNAs: Potential and Emerging Biomarkers for Diagnosis of Human Infectious Diseases.

Verma P; Pandey RK; Prajapati P; Prajapati VK
Review: FRONTIERS IN MICROBIOLOGY. 2016;7:206

Differential Expression of miRNA Regulates T Cell Differentiation and Plasticity During Visceral Leishmaniasis Infection.

Pandey RK; Sundar S; Prajapati VK

Employments

Affiliated to Research, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, 2023-2025
Postdoctoral Researcher, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, 2024-2024

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