Qing Cheng

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Articles

Article: EMBO JOURNAL. 2024;43(13):2789-2812
TRP14 is the rate-limiting enzyme for intracellular cystine reduction and regulates proteome cysteinylation
Marti-Andres P; Finamor I; Torres-Cuevas I; Perez S; Rius-Perez S; Colino-Lage H; Guerrero-Gomez D; Morato E; Marina A; Michalska P; Leon R; Cheng Q; Juranyi EP; Borbenyi-Galambos K; Millan I; Nagy P; Miranda-Vizuete A; Schmidt EE; Martinez-Ruiz A; Arner ESJ; Sastre J
Article: GENOME BIOLOGY AND EVOLUTION. 2024;16(3):evae041
Ancient Loss of Catalytic Selenocysteine Spurred Convergent Adaptation in a Mammalian Oxidoreductase
Rees J; Sarangi G; Cheng Q; Floor M; Andres AM; Oliva Miguel B; Villa-Freixa J; Arner ESJ; Castellano S
Article: ANGEWANDTE CHEMIE INTERNATIONAL EDITION. 2024;63(3):e202316488
Ultralight Ultrafast Enzymes
Zhang X; Meng Z; Beusch CM; Gharibi H; Cheng Q; Lyu H; Di Stefano L; Wang J; Saei AA; Vegvari A; Gaetani M; Zubarev RA
Journal article: ANGEWANDTE CHEMIE INTERNATIONAL EDITION. 2024;136(3)
Ultralight Ultrafast Enzymes**
Zhang X; Meng Z; Beusch CM; Gharibi H; Cheng Q; Lyu H; Di Stefano L; Wang J; Saei AA; Végvári Á; Gaetani M; Zubarev RA
Article: REDOX BIOCHEM CHEM. 2023;5-6:100015
Arsenic exposure and increased C-reactive protein are independently associated with lower erythrocyte glutathione peroxidase activity in Bangladeshi children.
Cheff DM; Skröder H; Akhtar E; Cheng Q; Hall MD; Raqib R; Kippler M; Vahter M; Arnér ESJ
Article: REDOX BIOLOGY. 2023;67:102897
TXNL1 has dual functions as a redox active thioredoxin-like protein as well as an ATP- and redox-independent chaperone
Andor A; Mohanraj M; Pato ZA; Uri K; Biri-Kovacs B; Cheng Q; Arner ESJ
Journal article: FREE RADICAL BIOLOGY AND MEDICINE. 2023;208:S118-S119
Beware of the kat among the proteins
Coppo L; Scholz A; Nolan E; Hernandez M; Wang X; Mishra P; Schnell R; Izumi A; Cheng Y; Dagnel M; Cheng Q; Arner E
Journal article: FREE RADICAL BIOLOGY AND MEDICINE. 2023;208:S102-S103
The anticancer compounds auranofin, TRi-1 and TRi-2 have distinct cytotoxicity profiles with regards to thioredoxin reductase inhibition
Gencheva R; Cheng Q; Arner E
Article: REDOX BIOLOGY. 2023;64:102806
Cardiolipin drives the catalytic activity of GPX4 on membranes: Insights from the R152H mutant
Roveri A; Di Giacinto F; Rossetto M; Cozza G; Cheng Q; Miotto G; Zennaro L; Paolo MLD; Arner ESJ; De Spirito M; Maiorino M; Ursini F
Article: REDOX BIOLOGY. 2023;63:102719
Development of an assay pipeline for the discovery of novel small molecule inhibitors of human glutathione peroxidases GPX1 and GPX4
Cheff DM; Cheng Q; Guo H; Travers J; Klumpp-Thomas C; Shen M; Arner ESJ; Hall MD
Article: REDOX BIOLOGY. 2023;62:102703
The ferroptosis inducing compounds RSL3 and ML162 are not direct inhibitors of GPX4 but of TXNRD1
Cheff DM; Huang C; Scholzen KC; Gencheva R; Ronzetti MH; Cheng Q; Hall MD; Arner ESJ
Article: REDOX BIOLOGY. 2023;59:102593
Side-by-side comparison of recombinant human glutathione peroxidases identifies overlapping substrate specificities for soluble hydroperoxides
Schwarz M; Loeser A; Cheng Q; Wichmann-Costaganna M; Schaedel P; Werz O; Arner ESJ; Kipp AP
Article: FRONTIERS IN MICROBIOLOGY. 2023;14:1198473
Novel gold(III)-dithiocarbamate complex targeting bacterial thioredoxin reductase: antimicrobial activity, synergy, toxicity, and mechanistic insights
Ratia C; Ballen V; Gabasa Y; Soengas RG; Velasco-de Andres M; Iglesias MJ; Cheng Q; Lozano F; Arner ESJ; Lopez-Ortiz F; Soto SM
Journal article: FREE RADICAL BIOLOGY AND MEDICINE. 2022;189:32-33
A mechanistic dissection of HyPer7, an ultrasensitive pH-independent biosensor
Daria E; Ekaterina B; Gerardo F-S; Qing C; Elias A; Joris M
Article: ELIFE. 2022;11:e74549
Redox regulation of PTPN22 affects the severity of T-cell-dependent autoimmune inflammation
James J; Chen Y; Hernandez CM; Forster F; Dagnell M; Cheng Q; Saei AA; Gharibi H; Lahore GF; astrand A; Malhotra R; Malissen B; Zubarev RA; Arner ESJ; Holmdahl R
Article: CHEM. 2022;8(5):1493-1517
Selective cellular probes for mammalian thioredoxin reductase TrxR1: Rational design of RX1, a modular 1,2-thiaselenane redox probe
Zeisel L; Felber JG; Scholzen KC; Poczka L; Cheff D; Maier MS; Cheng Q; Shen M; Hall MD; Arner ESJ; Thorn-Seshold J; Thorn-Seshold O
Article: REDOX BIOLOGY. 2022;51:102278
Biochemical and structural characterizations of thioredoxin reductase selenoproteins of the parasitic filarial nematodes Brugia malayi and Onchocerca volvulus
Fata F; Gencheva R; Cheng Q; Lullo R; Ardini M; Silvestri I; Gabriele F; Ippoliti R; Bulman CA; Sakanari JA; Williams DL; Arner ESJ; Angelucci F
Article: METHODS IN ENZYMOLOGY. 2022;662:95-118
Expressing recombinant selenoproteins using redefinition of a single UAG codon in an RF1-depleted E. coli host strain.
Cheng Q; Arnér ESJ
Article: REDOX BIOLOGY. 2021;48:102184
Comprehensive chemical proteomics analyses reveal that the new TRi-1 and TRi-2 compounds are more specific thioredoxin reductase 1 inhibitors than auranofin
Sabatier P; Beusch CM; Gencheva R; Cheng Q; Zubarev R; Arner ESJ
Article: REDOX BIOLOGY. 2021;46:102070
Production and purification of homogenous recombinant human selenoproteins reveals a unique codon skipping event in E. coli and GPX4-specific affinity to bromosulfophthalein
Cheng Q; Roveri A; Cozza G; Bordin L; Rohn I; Schwerdtle T; Kipp A; Ursini F; Maiorino M; Miotto G; Arner ESJ
Article: NATURE COMMUNICATIONS. 2021;12(1):1296
System-wide identification and prioritization of enzyme substrates by thermal analysis
Saei AA; Beusch CM; Sabatier P; Wells JA; Gharibi H; Meng Z; Chernobrovkin A; Rodin S; Nareoja K; Thorsell A-G; Karlberg T; Cheng Q; Lundstrom SL; Gaetani M; Vegvari A; Arner ESJ; Schuler H; Zubarev RA
Article: ANTIOXIDANTS. 2021;10(1):111
Qualitative Differences in Protection of PTP1B Activity by the Reductive Trx1 or TRP14 Enzyme Systems upon Oxidative Challenges with Polysulfides or H₂O₂ Together with Bicarbonate
Dagnell M; Cheng Q; Arner ESJ
Article: BREAST CANCER RESEARCH. 2020;22(1):80
Identification and targeting of selective vulnerability rendered by tamoxifen resistance
Singh M; Zhou X; Chen X; Santos GS; Peuget S; Cheng Q; Rihani A; Arner ESJ; Hartman J; Selivanova G
Article: ACS INFECTIOUS DISEASES. 2020;6(3):393-405
Characterization of Lead Compounds Targeting the Selenoprotein Thioredoxin Glutathione Reductase for Treatment of Schistosomiasis
Lyu H; Petukhov PA; Banta PR; Jadhav A; Lea WA; Cheng Q; Arner ESJ; Simeonov A; Thatcher GRJ; Angelucci F; Williams DL
Article: INORGANIC CHEMISTRY. 2020;59(5):2711-2718
Direct Observation of Methylmercury and Auranofin Binding to Selenocysteine in Thioredoxin Reductase
Pickering IJ; Cheng Q; Rengifo EM; Nehzati S; Dolgova NV; Kroll T; Sokaras D; George GN; Arner ESJ
Article: SCIENCE ADVANCES. 2020;6(1):eaax8358
Control of protein function through oxidation and reduction of persulfidated states
Doka E; Ida T; Dagnell M; Abiko Y; Luong NC; Balog N; Takata T; Espinosa B; Nishimura A; Cheng Q; Funato Y; Miki H; Fukuto JM; Prigge JR; Schmidt EE; Arner ESJ; Kumagai Y; Akaike T; Nagy P
Article: REDOX BIOLOGY. 2020;28:101335
Inhibition and crosslinking of the selenoprotein thioredoxin reductase-1 by p-benzoquinone
Shu N; Cheng Q; Arner ESJ; Davies MJ
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2019;294(33):12330-12338
Bicarbonate is essential for protein-tyrosine phosphatase 1B (PTP1B) oxidation and cellular signaling through EGF-triggered phosphorylation cascades
Dagnell M; Cheng Q; Rizvi SHM; Pace PE; Boivin B; Winterbourn CC; Arner ESJ
Article: ACS CHEMICAL BIOLOGY. 2018;13(8):2190-2202
Fragment-Based Discovery of a Regulatory Site in Thioredoxin Glutathione Reductase Acting as "Doorstop" for NADPH Entry
Silvestri I; Lyu H; Fata F; Boumis G; Miele AE; Ardini M; Ippoliti R; Bellelli A; Jadhav A; Lea WA; Simeonov A; Cheng Q; Arner ESJ; Thatcher GRJ; Petukhov PA; Williams DL; Angelucci F
Article: SCIENCE TRANSLATIONAL MEDICINE. 2018;10(428):eaaf7444
Irreversible inhibition of cytosolic thioredoxin reductase 1 as a mechanistic basis for anticancer therapy
Stafford WC; Peng X; Olofsson MH; Zhang X; Luci DK; Lu L; Cheng Q; Tresaugues L; Dexheimer TS; Coussens NP; Augsten M; Ahlzen H-SM; Orwar O; Ostman A; Stone-Elander S; Maloney DJ; Jadhav A; Simeonov A; Linder S; Arner ESJ
Article: METHODS IN MOLECULAR BIOLOGY. 2018;1661:231-240
Overexpression of Recombinant Selenoproteins in E. coli.
Cheng Q; Arnér ESJ
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2017;292(35):14371-14380
Thioredoxin reductase 1 and NADPH directly protect protein tyrosine phosphatase 1B from inactivation during H₂O₂ exposure
Dagnell M; Pace PE; Cheng Q; Frijhoff J; Ostman A; Arner ESJ; Hampton MB; Winterbourn CC
Article: FREE RADICAL BIOLOGY AND MEDICINE. 2017;106:270-277
Homozygous mutation in TXNRD1 is associated with genetic generalized epilepsy
Kudin AP; Baron G; Zsurka G; Hampel KG; Elger CE; Grote A; Weber Y; Lerche H; Thiele H; Nuernberg P; Schulz H; Ruppert A-K; Sander T; Cheng Q; Arner ESJ; Schomburg L; Seeher S; Fradejas-Villar N; Schweizer U; Kunz WS
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2017;292(13):5476-5487
Selenocysteine Insertion at a Predefined UAG Codon in a Release Factor 1 (RF1)-depleted Escherichia coli Host Strain Bypasses Species Barriers in Recombinant Selenoprotein Translation
Cheng Q; Arner ESJ
Article: EJNMMI RESEARCH. 2016;6(1):58
Preclinical PET imaging of EGFR levels: pairing a targeting with a non-targeting Sel-tagged Affibody-based tracer to estimate the specific uptake
Cheng Q; Wallberg H; Grafstrom J; Lu L; Thorell J-O; Olofsson MH; Linder S; Johansson K; Tegnebratt T; Arner ESJ; Stone-Elander S; Ahlzen H-SM; Stahl S
Article: FREE RADICAL BIOLOGY AND MEDICINE. 2016;99:426-435
Serum thioredoxin reductase is highly increased in mice with hepatocellular carcinoma and its activity is restrained by several mechanisms
Zhang L; Cheng Q; Zhang L; Wang Y; Merrill GF; Ilani T; Fass D; Arner ESJ; Zhang J
Article: ONCOTARGET. 2016;7(26):40233-40251
Indolin-2-one compounds targeting thioredoxin reductase as potential anticancer drug leads
Kaminska KK; Bertrand HC; Tajima H; Stafford WC; Cheng Q; Chen W; Wells G; Arner ESJ; Chew E-H
Article: FREE RADICAL BIOLOGY AND MEDICINE. 2016;94:110-120
Details in the catalytic mechanism of mammalian thioredoxin reductase 1 revealed using point mutations and juglone-coupled enzyme activities
Xu J; Cheng Q; Arner ESJ
Article: SCIENCE ADVANCES. 2016;2(1):e1500968
A novel persulfide detection method reveals protein persulfide- and polysulfide-reducing functions of thioredoxin and glutathione systems
Doka E; Pader I; Biro A; Johansson K; Cheng Q; Ballago K; Prigge JR; Pastor-Flores D; Dick TP; Schmidt EE; Arner ESJ; Nagy P
Article: CELL DEATH AND DISEASE. 2015;6(1):e1616
The conserved Trp114 residue of thioredoxin reductase 1 has a redox sensor-like function triggering oligomerization and crosslinking upon oxidative stress related to cell death
Xu J; Eriksson SE; Cebula M; Sandalova T; Hedstrom E; Pader I; Cheng Q; Myers CR; Antholine WE; Nagy P; Hellman U; Selivanova G; Lindqvist Y; Arner ESJ
Article: NUCLEIC ACIDS RESEARCH (NAR). 2013;41(21):9800-9811
Wobble decoding by the Escherichia coli selenocysteine insertion machinery
Xu J; Croitoru V; Rutishauser D; Cheng Q; Arner ESJ
Article: FREE RADICAL BIOLOGY AND MEDICINE. 2013;60:183-194
Redox activation of Fe(III)-thiosemicarbazones and Fe(III)-bleomycin by thioredoxin reductase: specificity of enzymatic redox centers and analysis of reactive species formation by ESR spin trapping
Myers JM; Cheng Q; Antholine WE; Kalyanaraman B; Filipovska A; Arner ESJ; Myers CR
Article: BIOCHIMICA ET BIOPHYSICA ACTA: INTERNATIONAL JOURNAL OF BIOCHEMISTRY AND BIOPHYSICS. 2013;1830(3):2562-2573
Site-specifically ¹¹C-labeled Sel-tagged annexin A5 and a size-matched control for dynamic in vivo PET imaging of protein distribution in tissues prior to and after induced cell death
Cheng Q; Lu L; Grafstrom J; Olofsson MH; Thorell J-O; Samen E; Johansson K; Ahlzen H-S; Linder S; Arner ESJ; Stone-Elander S
Article: JOURNAL OF NUCLEAR MEDICINE. 2012;53(9):1446-1453
HER2-positive tumors imaged within 1 hour using a site-specifically 11C-labeled Sel-tagged affibody molecule.
Wållberg H; Grafström J; Cheng Q; Lu L; Martinsson Ahlzén H-S; Samén E; Thorell J-O; Johansson K; Dunås F; Olofsson MH; Stone-Elander S; Arnér ESJ; Ståhl S
Article: PLOS ONE. 2012;7(8):e42151
Combining [11C]-AnxA5 PET imaging with serum biomarkers for improved detection in live mice of modest cell death in human solid tumor xenografts.
Cheng Q; Lu L; Grafström J; Olofsson MH; Thorell J-O; Samén E; Johansson K; Ahlzén H-S; Stone-Elander S; Linder S; Arnér ESJ; Sel-tag Imaging Project
Article: FREE RADICAL BIOLOGY AND MEDICINE. 2011;50(9):1114-1123
Inhibition of thioredoxin reductase 1 by porphyrins and other small molecules identified by a high-throughput screening assay
Prast-Nielsen S; Dexheimer TS; Schultz L; Stafford WC; Cheng Q; Xu J; Jadhav A; Arner ESJ; Simeonov A
Article: FREE RADICAL BIOLOGY AND MEDICINE. 2011;50(6):689-699
Substrate and inhibitor specificities differ between human cytosolic and mitochondrial thioredoxin reductases: Implications for development of specific inhibitors
Rackham O; Shearwood A-MJ; Thyer R; McNamara E; Davies SMK; Callus BA; Miranda-Vizuete A; Berners-Price SJ; Cheng Q; Arner ESJ; Filipovska A
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2011;108(3):1064-1069
Selenoprotein TRXR-1 and GSR-1 are essential for removal of old cuticle during molting in Caenorhabditis elegans
Stenvall J; Fierro-Gonzalez JC; Swoboda P; Saamarthy K; Cheng Q; Cacho-Valadez B; Arner ESJ; Persson OP; Miranda-Vizuete A; Tuck S
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2010;285(28):21708-21723
The Selenium-independent Inherent Pro-oxidant NADPH Oxidase Activity of Mammalian Thioredoxin Reductase and Its Selenium-dependent Direct Peroxidase Activities
Cheng Q; Antholine WE; Myers JM; Kalyanaraman B; Arner ESJ; Myers CR
Article: ALLERGY. EUROPEAN JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2009;64(6):919-926
Prolonged antigen-exposure with carbohydrate particle based vaccination prevents allergic immune responses in sensitized mice
Thunberg S; Neimert-Andersson T; Cheng Q; Wermeling F; Bergstrom U; Swedin L; Dahlen S-E; Arner E; Scheynius A; Karlsson MCI; Gafvelin G; van Hage M; Gronlund H
Article: FREE RADICAL BIOLOGY AND MEDICINE. 2009;46(7):893-904
Highly active dimeric and low-activity tetrameric forms of selenium-containing rat thioredoxin reductase 1
Rengby O; Cheng Q; Vahter M; Jornvall H; Arner ESJ
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2009;284(6):3998-4008
Crystal Structure and Catalysis of the Selenoprotein Thioredoxin Reductase 1
Cheng Q; Sandalova T; Lindqvist Y; Arner ESJ
Article: CHEMBIOCHEM. 2006;7(12):1976-1981
Selenolthiol and dithiol C-terminal tetrapeptide motifs for one-step purification and labeling of recombinant proteins produced in E. coli
Cheng Q; Johansson L; Thorell J-O; Fredriksson A; Samen E; Stone-Elander S; Arner ESJ
Article: NATURE PROTOCOLS. 2006;1(2):604-613
Tagging recombinant proteins with a Sel-tag for purification, labeling with electrophilic compounds or radiolabeling with ¹¹C
Cheng Q; Stone-Elander S; Arner ESJ
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Conference publication: FREE RADICAL BIOLOGY AND MEDICINE. 2023;201:37-38
IS THERE A SUBSTRATE SPECIFICITY OF GLUTATHIONE PEROXIDASE ISOFORMS?
Schwarz M; Cheng Q; Loeser A; Arner ESJ; Kipp AP
Conference publication: FREE RADICAL BIOLOGY AND MEDICINE. 2023;201:39
THE ANTICANCER COMPOUNDS AURANOFIN, TRI-1 AND TRI-2 HAVE DISTINCT CYTOTOXICITY PROFILES WITH REGARDS TO THIOREDOXIN REDUCTASE INHIBITION
Gencheva R; Cheng Q; Arner E
Conference publication: FREE RADICAL BIOLOGY AND MEDICINE. 2023;201:15
TRP14 IS THE CELLULAR CYSTINE REDUCTASE AND ALSO REDUCES CYSTEINYLATED PROTEINS
Marti-Andres P; Isabela; Perez S; Rius-Perez S; Torres-Cuevas I; Colino-Lage H; Guerrero-Gomez D; Morato E; Marina A; Michalska P; Leon R; Cheng Q; Miranda-Vizuete A; Schmidt EE; Martinez-Ruiz A; Arner ESJ; Sastre J
Preprint: BIORXIV. 2023
Ancient loss of catalytic selenocysteine spurred convergent adaptation in a mammalian oxidoreductase
Rees J; Sarangi G; Cheng Q; Floor M; Andrés A; Miguel BO; Villà-Freixa J; Arnér ESJ; Castellano S
Conference publication: EUROPEAN BIOPHYSICS JOURNAL. 2023;52(SUPPL 1):S50
Probing Toxic Metals and Metalloids in Redox Biology using Synchrotron X-rays
George G; Pickering I; Rengifo EM; Dolgova N; Cheng Q; Arner E
Review: FREE RADICAL BIOLOGY AND MEDICINE. 2022;190:320-338
Thioredoxin reductase selenoproteins from different organisms as potential drug targets for treatment of human diseases
Gencheva R; Cheng Q; Arner ESJ
Preprint: CHEMRXIV. 2022
Selective cellular probes for mammalian thioredoxin reductase TrxR1: rational design of RX1, a modular 1,2-thiaselenane redox probe
Zeisel L; Felber JG; Poczka L; Scholzen K; Cheff D; Maier MS; Cheng Q; Shen M; Hall MD; Arnér ESJ; Thorn-Seshold J; Thorn-Seshold O
Conference publication: FREE RADICAL BIOLOGY AND MEDICINE. 2022;180:68
Development of a chemical probe that selectively images the activity of mammalian Thioredoxin Reductase 1
Zeisel L; Felber J; Poczka L; Scholzen K; Maier M; Cheng Q; Arner E; Thorn-Seshold J; Thorn-Seshold O
Preprint: RESEARCH SQUARE. 2021
Ultralight ultrafast enzymes
Zhang X; Meng Z; Beusch C; Gharibi H; Cheng Q; Stefano L; Wang J; Saei A; Vegvari A; Gaetani M; Zubarev R
Preprint: BIORXIV. 2021
Redox regulation of PTPN22 affects the severity of T cell dependent autoimmune inflammation
James J; Chen Y; Hernandez C; Forster F; Dagnell M; Cheng Q; Saei A; Gharibi H; Lahore GF; Åstrand A; Malhotra R; Malissen B; Zubarev R; Arnér ESJ; Holmdahl R
Preprint: CHEMRXIV. 2021
Selective cellular probes for mammalian thioredoxin reductase TrxR1: rational design of RX1, a modular 1,2-thiaselenane redox probe
Zeisel L; Felber JG; Poczka L; Scholzen K; Maier MS; Cheng Q; Arnér ESJ; Thorn-Seshold J; Thorn-Seshold O
Preprint: CHEMRXIV. 2021
Selective cellular probes for mammalian thioredoxin reductase TrxR1: rational design of RX1, a modular 1,2-thiaselenane redox probe
Zeisel L; Felber JG; Poczka L; Scholzen K; Maier MS; Cheng Q; Arnér ESJ; Thorn-Seshold J; Thorn-Seshold O
Preprint: RESEARCH SQUARE. 2021
SIESTA as a universal unbiased proteomics approach for identification and prioritization of enzyme substrates
Saei AA; Beusch C; Sabatier P; Wells JA; Gharibi H; Meng Z; Chernobrovkin A; Rodin S; Näreoja K; Thorsell A-G; Karlberg T; Cheng Q; Lundström S; Gaetani M; Végvári Á; Arnér ESJ; Schüler H; Zubarev R
Conference publication: FREE RADICAL BIOLOGY AND MEDICINE. 2019;145:S21
Targeting of the Selenoprotein Thioredoxin Reductase-1 by p-benzoquinone
Shu N; Amer E; Cheng Q; Davies M
Book chapter: SELENIUM RESEARCH FOR ENVIRONMENT AND HUMAN HEALTH: PERSPECTIVES, TECHNOLOGIES AND ADVANCEMENTS. 2019;p. 153-154
New developments in recombinant selenoprotein production
Cheng Q; Arnér ESJ
Published conference paper: BIOCHIMICA ET BIOPHYSICA ACTA - GENERAL SUBJECTS. 2018;1862(11):2511-2517
Efficient selenocysteine-dependent reduction of toxoflavin by mammalian thioredoxin reductase
Gencheva R; Cheng Q; Arner ESJ
Preprint: BIORXIV. 2018
System-wide identification and prioritization of enzyme substrates by thermal analysis (SIESTA)
Saei AA; Beusch C; Sabatier P; Wells JA; Chernobrovkin A; Rodin S; Näreoja K; Thorsell A-G; Karlberg T; Cheng Q; Lundström S; Gaetani M; Végvári Á; Arnér ESJ; Schüler H; Zubarev R
Conference publication: FREE RADICAL BIOLOGY AND MEDICINE. 2018;120:S46
Screening for novel inhibitors of glutathione peroxidase
Cheff DM; Cheng Q; Hall MD; Arner E
Conference publication: FREE RADICAL BIOLOGY AND MEDICINE. 2018;120:S36
Bicarbonate is required for hydrogen peroxide-dependent inactivation of PTP1B in presence of the Trx system and peroxiredoxin
Dagnell M; Cheng Q; Pace PE; Hampton MB; Winterbourn CC; Arner ESJ
Conference publication: FREE RADICAL BIOLOGY AND MEDICINE. 2016;100:S47
Thioredoxin Reductase 1 Directly Protects Protein Tyrosine Phosphatase 1B from Inactivation by H₂O₂
Dagnell M; Pace P; Cheng Q; Frijhoff J; Ostman A; Arner E; Hampton M; Winterbourn C
Thesis / dissertation: 2010
Development of a Sel-tag for multimodality imaging and studies of mammalian thioredoxin reductase 1
Cheng, Qing
Meeting abstract: FREE RADICAL BIOLOGY AND MEDICINE. 2010;49:S98-S99
The Interactions of Thioredoxin Reductase with Quinones and Acrolein: Covalent Adducts and Stimulation of NADPH Oxidase Activity
Myers CR; Cheng Q; Myers JM; Antholine WE; Arner ESJ
Conference publication: JOURNAL OF LABELLED COMPOUNDS AND RADIOPHARMACEUTICALS. 2005;48:S38
EVALUATION OF NOVEL SELENOLTHIOL AND DITHIOL SEL-TAG VARIANTS FOR PURIFICATION AND ¹¹C-LABELING OF RECOMBINANT PROTEINS PRODUCED IN E. COLI
Cheng Q; Johansson L; Fredriksson A; Thorell J-O; Stone-Elander S; Arner ESJ
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Employments

Senior Lab Manager, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, 2015-

Degrees and Education

Degree Of Doctor Of Philosophy, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, 2010

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