Petronella Pettersson

Doctoral project: Clinical factors and predicitve markers for improved outcomes in laryngeal cancer.

Principal supervisor: Rusana Bark MD, PhD

Co-supervisors: Linda Marklund MD, Prof and Elin Marsk MD, PhD

The overall aim of this thesis is to identify clinical factors, prognostic markers, and diagnostic methods that may contribute to more individualized treatment of laryngeal cancer. The goal is to contribute to improved survival and reduced treatment-related morbidity. This is investigated through six substudies: three retrospective cohort studies examining complications, oncological outcomes, and voice function following laryngectomy, one retrospective study of tumour markers associated with tumour aggressiveness and radiosensitivity, and one prospective cohort study mapping lymphatic drainage from advanced laryngeal tumours.