Per Eriksson

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About me

Per Eriksson was appointed Professor of Cardiovascular Medicine at Karolinska Institutet in 2007. His research is about the underlying molecular mechanism of aortic aneurysm development. Aortic aneurysm is a silent disease, and the first manifestation is often aortic dissection or aortic rupture, both lethal conditions unless surgery is performed acutely.

Articles

Article: PLOS GENETICS. 2024;20(6):e1011285

An endothelial regulatory module links blood pressure regulation with elite athletic performance

Fegraeus K; Rosengren MK; Naboulsi R; Orlando L; Abrink M; Jouni A; Velie BD; Raine A; Egner B; Mattsson CM; Lang K; Zhigulev A; Bjorck HM; Franco-Cereceda A; Eriksson P; Andersson G; Sahlen P; Meadows JRS; Lindgren G
Article: BIOMEDICINES. 2024;12(4):737

Determinants of Carotid Wall Echolucency in a Cohort of European High Cardiovascular Risk Subjects: A Cross-Sectional Analysis of IMPROVE Baseline Data

Frigerio B; Coggi D; Bonomi A; Amato M; Capra N; Colombo GI; Sansaro D; Ravani A; Savonen K; Giral P; Gallo A; Pirro M; Gigante B; Eriksson P; Strawbridge RJ; Mulder DJ; Tremoli E; Veglia F; Baldassarre D
Article: BMJ OPEN. 2024;14(3):e067977

Predictive machine learning models for ascending aortic dilatation in patients with bicuspid and tricuspid aortic valves undergoing cardiothoracic surgery: a prospective, single-centre and observational study

Gaye B; Vignac M; Gadin JR; Ladouceur M; Caidahl K; Olsson C; Franco-Cereceda A; Eriksson P; Bjorck HM
Article: NAT CARDIOVASC RES. 2024;3(3):356-371

Kupffer cells dictate hepatic responses to the atherogenic dyslipidemic insult

Di Nunzio G; Hellberg S; Zhang Y; Ahmed O; Wang J; Zhang X; Bjoerck HM; Chizh V; Schipper R; Aulin H; Francis R; Fagerberg L; Gistera A; Metso J; Manfe V; Franco-Cereceda A; Eriksson P; Jauhiainen M; Hagberg CE; Olofsson PS; Malin SG
Article: CARDIOVASCULAR RESEARCH. 2023;119(16):2594-2606

A machine learning based approach to identify carotid subclinical atherosclerosis endotypes

Chen QS; Bergman O; Ziegler L; Baldassarre D; Veglia F; Tremoli E; Strawbridge RJ; Gallo A; Pirro M; Smit AJ; Kurl S; Savonen K; Lind L; Eriksson P; Gigante B
Journal article: EUROPEAN HEART JOURNAL. 2023;44:ehad655.2030

Hemodynamics and plasma biomarkers in individuals with mild-to-moderate ascending aortic dilatation and tricuspid aortic valves

Hammareus F; Trenti C; Bjorck HM; Engvall J; Eriksson P; Lekedal H; Lundberg A; Nilsson L; Swahn E; Jonasson L; Dyverfeldt P
Article: JOURNAL OF MOLECULAR MEDICINE-JMM. 2023;101(10):1323-1333

SPP1/osteopontin: a driver of fibrosis and inflammation in degenerative ascending aortic aneurysm?

Freiholtz D; Bergman O; Pradhananga S; Lang K; Poujade F-A; Granath C; Olsson C; Franco-Cereceda A; Sahlen P; Eriksson P; Bjorck HM
Article: CLINICAL PROTEOMICS. 2023;20(1):31

Proteomic analysis of 92 circulating proteins and their effects in cardiometabolic diseases

Carland C; Png G; Malarstig A; Kho PF; Gustafsson S; Michaelsson K; Lind L; Tsafantakis E; Karaleftheri M; Dedoussis G; Ramisch A; Macdonald-Dunlop E; Klaric LK; Joshi P; Chen YM; Bjoerck H; Eriksson P; Carrasco-Zanini J; Wheeler E; Suhre K; Gilly A; Zeggini E; Vinuela AT; Dermitzakis EF; Wilson J; Langenberg C; Thareja G; Halama A; Schmidt F; Zanetti D; Assimes T
Journal article: ATHEROSCLEROSIS. 2023;379:s54

BICUSPID AORTIC VALVE AORTOPATHY IS CHARACTERIZED BY EMBRYONIC ENDOTHELIAL TO MESENCHYMAL TRANSITION AND ENDOTHELIAL INSTABILITY

Freiholtz D; Bergman O; Lang K; Poujade F-A; Paloschi V; Granath C; Lindeman J; Olsson C; Franco-Cereceda A; Eriksson P; Bjorck HM
Journal article: ATHEROSCLEROSIS. 2023;379:s31

POSSIBLE ROLE OF SPP1 IN DEGENERATIVE ASCENDING AORTIC ANEURYSM FORMATION

Freiholtz D; Bergman O; Poujade F-A; Granath C; Lang K; Olsson C; Franco-Cereceda A; Bjorck HM; Eriksson P
Article: JAMA CARDIOLOGY. 2023;8(8):721-731

Novel Association of the NOTCH Pathway Regulator MIB1 Gene With the Development of Bicuspid Aortic Valve

Tessler I; Albuisson J; Pineiro-Sabaris R; Verstraeten A; Kaya HEK; Siguero-Alvarez M; Goudot G; MacGrogan D; Luyckx I; Shpitzen S; Levin G; Kelman G; Reshef N; Mananet H; Holdcraft J; Muehlschlegel JD; Peloso GM; Oppenheim O; Cheng C; Mazzella J-M; Andelfinger G; Mital S; Eriksson P; Billon C; Heydarpour M; Dietz HC; Jeunemaitre X; Leitersdorf E; Sprinzak D; Blacklow SC; Body SC; Carmi S; Loeys B; de la Pompa JL; Gilon D; Messas E; Durst R
Article: JOURNAL OF MOLECULAR MEDICINE-JMM. 2023;101(7):801-811

Bicuspid aortic valve aortopathy is characterized by embryonic epithelial to mesenchymal transition and endothelial instability

Freiholtz D; Bergman O; Lang K; Poujade F-A; Paloschi V; Granath C; Lindeman JHN; Olsson C; Franco-Cereceda A; Eriksson P; Bjorck HM
Journal article: NAT CARDIOVASC RES. 2023;2(7):629-644

The VE-cadherin/AmotL2 mechanosensory pathway suppresses aortic inflammation and the formation of abdominal aortic aneurysms

Zhang Y; Zhang Y; Hutterer E; Hultin S; Bergman O; Kolbeinsdottir S; Jin H; Forteza MJ; Ketelhuth DFJ; Roy J; Hedin U; Enge M; Matic L; Eriksson P; Holmgren L
Article: CURRENT RESEARCH IN TRANSLATIONAL MEDICINE. 2023;71(1):103374

Causal analysis of plasma IL-8 on carotid intima media thickness, a measure of subclinical atherosclerosis

Velasquez IM; Malarstig A; Baldassarre D; Borne Y; de Faire U; Engstrom G; Eriksson P; Giral P; Humphries SE; Kurl S; Leander K; Lind L; Linden A; Orsini N; Pirro M; Silveira A; Smit AJ; Tremoli E; Veglia F; Strawbridge RJ; Gigante B
Article: ANNALS OF THORACIC SURGERY. 2022;114(5):1665-1670

Sex Differences in Aortopathy and Valve Diseases Among Patients Undergoing Cardiac Surgical Procedure

Vignac M; Bjorck HM; Olsson C; Eriksson MJ; Jouven X; Michos ED; Franco-Cereceda A; Eriksson P; Gaye B
Article: BRITISH JOURNAL OF PHARMACOLOGY. 2022;179(19):4709-4721

The tyrosine kinase inhibitor nilotinib targets the discoidin domain receptor DDR2 in calcific aortic valve stenosis

Carracedo M; Pawelzik S-C; Artiach G; Pouwer MG; Plunde O; Saliba-Gustafsson P; Ehrenborg E; Eriksson P; Pieterman E; Stenke L; Princen HMG; Franco-Cereceda A; Back M
Article: ANNALS OF THE RHEUMATIC DISEASES. 2022;81(8):1151-1161

Auxilin is a novel susceptibility gene for congenital heart block which directly impacts fetal heart function

Meisgen S; Hedlund M; Ambrosi A; Folkersen L; Ottosson V; Forsberg D; Thorlacius GE; Biavati L; Strandberg L; Mofors J; Ramskold D; Ruhrmann S; Meneghel L; Nyberg W; Espinosa A; Hamilton RM; Franco-Cereceda A; Hamsten A; Olsson T; Greene L; Eriksson P; Gemzell-Danielsson K; Salomonsson S; Kuchroo VK; Herlenius E; Kockum I; Sonesson S-E; Wahren-Herlenius M
Journal article: ATHEROSCLEROSIS. 2022;355:37

The role of rare enhancer variants in bicuspid aortic valve pathology

Zhigulev A; Lång K; Pradhananga S; Spalinskas R; Franco-Cereceda A; Björck H; Eriksson P; Sahlén P
Journal article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2022;42:a419

Therapeutic Potential Of The Proprotein Convertase Subtilisin/Kexin ( PCSK) Family In Vascular Disease

Suur BE; Chemaly M; Liljeqvist ML; Djordjevic D; Stenemo M; Bergman O; Karlof E; Lengquist M; Odeberg J
Article: ATHEROSCLEROSIS. 2022;348:8-15

A novel anti-inflammatory role links the CARS2 locus to protection from coronary artery disease

Dang A-T; Turner AW; Lau P; Mohottalage D; Fong YKS; Eriksson P; Folkersen L; Matic L; Hedin U; Soubeyrand S; McPherson R
Article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2022;42(5):659-676

Plaque Evaluation by Ultrasound and Transcriptomics Reveals BCLAF1 as a Regulator of Smooth Muscle Cell Lipid Transdifferentiation in Atherosclerosis

Rykaczewska U; Zhao Q; Saliba-Gustafsson P; Lengquist M; Kronqvist M; Bergman O; Huang Z; Lund K; Waden K; Pons Vila Z; Caidahl K; Skogsberg J; Vukojevic V; Lindeman JHN; Roy J; Hansson GK; Treuter E; Leeper NJ; Eriksson P; Ehrenborg E; Razuvaev A; Hedin U; Matic L
Article: FRONTIERS IN PHARMACOLOGY. 2022;13:988561

Therapeutic potential of the Proprotein Convertase Subtilisin/Kexin family in vascular disease

Suur BE; Chemaly M; Liljeqvist ML; Djordjevic D; Stenemo M; Bergman O; Karlof E; Lengquist M; Odeberg J; Hurt-Camejo E; Eriksson P; Ketelhuth DFJ; Roy J; Hedin U; Nyberg M; Matic L
Article: BIOFACTORS. 2022;48(1):100-110

Neutrophil to lymphocyte ratio is not related to carotid atherosclerosis progression and cardiovascular events in the primary prevention of cardiovascular disease: Results from the IMPROVE study

Mannarino MR; Bianconi V; Gigante B; Strawbridge RJ; Savonen K; Kurl S; Giral P; Smit A; Eriksson P; Tremoli E; Veglia F; Baldassarre D; Pirro M
Article: JOURNAL OF VASCULAR SURGERY. 2021;74(6):2023-2029

Sex hormones in men with abdominal aortic aneurysm

Villard C; Roy J; Bogdanovic M; Eriksson P; Hultgren R
Article: JOURNAL OF INTERNAL MEDICINE. 2021;290(5):1061-1070

Arginase 1 is upregulated at admission in patients with ST-elevation myocardial infarction

Tengbom J; Cederstrom S; Verouhis D; Bohm F; Eriksson P; Folkersen L; Gabrielsen A; Jernberg T; Lundman P; Persson J; Saleh N; Settergren M; Sorensson P; Tratsiakovich Y; Tornvall P; Jung C; Pernow J
Article: OPEN HEART. 2021;8(2):e001694

Interleukin 6 trans-signalling and the risk of future cardiovascular events in men and women

Miri Y; Leander K; Eriksson P; Gigante B; Ziegler L
Article: COMMUNICATIONS BIOLOGY. 2021;4(1):1109

Prenylcysteine oxidase 1, an emerging player in atherosclerosis

Banfi C; Baetta R; Barbieri SS; Brioschi M; Guarino A; Ghilardi S; Sandrini L; Eligini S; Polvani G; Bergman O; Eriksson P; Tremoli E
Article: HEART. 2021;107(14):1167-1172

Relative survival after aortic valve surgery in patients with bicuspid aortic valves

Glaser N; Jackson V; Eriksson P; Sartipy U; Franco-Cereceda A
Article: SCIENTIFIC REPORTS. 2021;11(1):7866

Intake of food rich in saturated fat in relation to subclinical atherosclerosis and potential modulating effects from single genetic variants

Laguzzi F; Maitusong B; Strawbridge RJ; Baldassarre D; Veglia F; Humphries SE; Rauramaa R; Kurl S; Smit AJ; Giral P; Silveira A; Tremoli E; Hamsten A; de Faire U; Gigante B; Leander K
Article: CARDIOVASCULAR ULTRASOUND. 2021;19(1):14

Pre- and postoperative left atrial and ventricular volumetric and deformation analyses in severe aortic regurgitation

Jenner J; Ilami A; Petrini J; Eriksson P; Franco-Cereceda A; Eriksson MJ; Caidahl K
Article: SCIENTIFIC REPORTS. 2021;11(1):632

The overlap of genetic susceptibility to schizophrenia and cardiometabolic disease can be used to identify metabolically different groups of individuals

Strawbridge RJ; Johnston KJA; Bailey MES; Baldassarre D; Cullen B; Eriksson P; deFaire U; Ferguson A; Gigante B; Giral P; Graham N; Hamsten A; Humphries SE; Kurl S; Lyall DM; Lyall LM; Pell JP; Pirro M; Savonen K; Smit AJ; Tremoli E; Tomainen T-P; Veglia F; Ward J; Sennblad B; Smith DJ
Article: NATURE COMMUNICATIONS. 2021;12(1):24

Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability

Lagou V; Maegi R; Hottenga J-J; Grallert H; Perry JRB; Bouatia-Naji N; Marullo L; Rybin D; Jansen R; Min JL; Dimas AS; Ulrich A; Zudina L; Gadin JR; Jiang L; Faggian A; Bonnefond A; Fadista J; Stathopoulou MG; Isaacs A; Willems SM; Navarro P; Tanaka T; Jackson AU; Montasser ME; O'Connell JR; Bielak LF; Webster RJ; Saxena R; Stafford JM; Pourcain BS; Timpson NJ; Salo P; Shin S-Y; Amin N; Smith AV; Li G; Verweij N; Goel A; Ford I; Johnson PCD; Johnson T; Kapur K; Thorleifsson G; Strawbridge RJ; Rasmussen-Torvik LJ; Esko T; Mihailov E; Fall T; Fraser RM; Mahajan A; Kanoni S; Giedraitis V; Kleber ME; Silbernagel G; Meyer J; Mueller-Nurasyid M; Ganna A; Sarin A-P; Yengo L; Shungin D; Luan J; Horikoshi M; An P; Sanna S; Boettcher Y; Rayner NW; Nolte IM; Zemunik T; Iperen EV; Kovacs P; Hastie ND; Wild SH; McLachlan S; Campbell S; Polasek O; Carlson O; Egan J; Kiess W; Willemsen G; Kuusisto J; Laakso M; Dimitriou M; Hicks AA; Rauramaa R; Bandinelli S; Thorand B; Liu Y; Miljkovic I; Lind L; Doney A; Perola M; Hingorani A; Kivimaki M; Kumari M; Bennett AJ; Groves CJ; Herder C; Koistinen HA; Kinnunen L; Faire UD; Bakker SJL; Uusitupa M; Palmer CNA; Jukema JW; Sattar N; Pouta A; Snieder H; Boerwinkle E; Pankow JS; Magnusson PK; Krus U; Scapoli C; de Geus EJCN; Blueher M; Wolffenbuttel BHR; Province MA; Abecasis GR; Meigs JB; Hovingh GK; Lindstroem J; Wilson JF; Wright AF; Dedoussis GV; Bornstein SR; Schwarz PEH; Toenjes A; Winkelmann BR; Boehm BO; Maerz W; Metspalu A; Price JF; Deloukas P; Koerner A; Lakka TA; Keinanen-Kiukaanniemi SM; Saaristo TE; Bergman RN; Tuomilehto J; Wareham NJ; Langenberg C; Maennistoe S; Franks PW; Hayward C; Vitart V; Kaprio J; Visvikis-Siest S; Balkau B; Altshuler D; Rudan I; Stumvoll M; Campbell H; van Duijn CM; Gieger C; Illig T; Ferrucci L; Pedersen NL; Pramstaller PP; Boehnke M; Frayling TM; Shuldiner AR; Peyser PA; Kardia SLR; Palmer LJ; Penninx BW; Meneton P; Harris TB; Navis G; Harst PVD; Smith GD; Forouhi NG; Loos RJF; Salomaa V; Soranzo N; Boomsma DI; Groop L; Tuomi T; Hofman A; Munroe PB; Gudnason V; Siscovick DS; Watkins H; Lecoeur C; Vollenweider P; Franco-Cereceda A; Eriksson P; Jarvelin M-R; Stefansson K; Hamsten A; Nicholson G; Karpe F; Dermitzakis ET; Lindgren CM; McCarthy MI; Froguel P; Kaakinen MA; Lyssenko V; Watanabe RM; Ingelsson E; Florez JC; Dupuis J; Barroso I; Morris AP; Prokopenko I
Journal article: ATHEROSCLEROSIS. 2020;315:e22-e23

Repression of MAP1LC3A during atherosclerosis progression plays an important role in the regulation of vascular smooth muscle cell phenotype

Ehrenborg E; Paloschi V; Goncalves I; Saliba-Gustafsson P; Werngren O; Matic L; Skogsberg J; Jin H; Ketelhuth DFJ; Maegdefessel L; Hedin U; Eriksson P; Magné J
Article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2020;40(11):2700-2713

Tunica-Specific Transcriptome of Abdominal Aortic Aneurysm and the Effect of Intraluminal Thrombus, Smoking, and Diameter Growth Rate

Lindquist Liljeqvist M; Hultgren R; Bergman O; Villard C; Kronqvist M; Eriksson P; Roy J
Article: GENES. 2020;11(11):E1243-1243

Genetic Variants Associated with Non-Alcoholic Fatty Liver Disease Do Not Associate with Measures of Sub-Clinical Atherosclerosis: Results from the IMPROVE Study

Castaldo L; Laguzzi F; Strawbridge RJ; Baldassarre D; Veglia F; Vigo L; Tremoli E; de Faire U; Eriksson P; Smit AJ; Aubrecht J; Leander K; Pirro M; Giral P; Ritieni A; Di Minno G; Malarstig A; Gigante B
Article: CELLULAR IMMUNOLOGY. 2020;355:104148

Promoter anchored interaction landscape of THP-1 macrophages captures early immune response processes

Pradhananga S; Spalinskas R; Poujade F-A; Eriksson P; Sahlen P
Article: CELLS. 2020;9(7):E1710-1710

TLR7 Expression Is Associated with M2 Macrophage Subset in Calcific Aortic Valve Stenosis

Karadimou G; Plunde O; Pawelzik S-C; Carracedo M; Eriksson P; Franco-Cereceda A; Paulsson-Berne G; Back M
Article: CIRCULATION-GENOMIC AND PRECISION MEDICINE. 2020;13(3):e002710-148

FADS1 (Fatty Acid Desaturase 1) Genotype Associates With Aortic Valve FADS mRNA Expression, Fatty Acid Content and Calcification

Plunde O; Larsson SC; Artiach G; Thanassoulis G; Carracedo M; Franco-Cereceda A; Eriksson P; Back M
Article: CIRCULATION RESEARCH. 2020;126(5):571-585

PCSK6 Is a Key Protease in the Control of Smooth Muscle Cell Function in Vascular Remodeling

Rykaczewska U; Suur BE; Rohl S; Razuvaev A; Lengquist M; Sabater-Lleal M; van der Laan SW; Miller CL; Wirka RC; Kronqvist M; Diez MG; Vesterlund M; Gillgren P; Odeberg J; Lindeman JH; Veglia F; Humphries SE; de Faire U; Baldassarre D; Tremoli E; Lehtio J; Hansson GK; Paulsson-Berne G; Pasterkamp G; Quertermous T; Hamsten A; Eriksson P; Hedin U; Matic L
Article: GENES AND IMMUNITY. 2020;21(2):100-108

Analysis of the genetic variants associated with circulating levels of sgp130. Results from the IMPROVE study

Bonomi A; Veglia F; Baldassarre D; Strawbridge RJ; Golabkesh Z; Sennblad B; Leander K; Smit AJ; Giral P; Humphries SE; Tremoli E; Hamsten A; de Faire U; Gigante B; Sirtori CR; Castelnuovo S; Calabresi L; Amato M; Frigerio B; Ravani A; Sansaro D; Coggi D; Tedesco CC; Eriksson P; Silveira A; Laguzzi F; Cooper J; Acharya J; Huttunen K; Rauramaa E; Pekkarinen H; Penttila IM; Torronen J; Rauramaa R; Van Gessel AI; Van Roon AM; Teune GC; Kuipers WD; Bruin M; Nicolai A; Haarsma-Jorritsma P; Mulder DJ; Bilo HJG; Smeets GH; Beaudeux JL; Kahn JF; Carreau V; Kontush A; Karppi J; Nurmi T; Nyyssonen K; Salonen R; Tuomainen TP; Tuomainen J; Kauhanen J; Kurl S; Vaudo G; Alaeddin A; Siepi D; Lupattelli G; Mannarino E
Article: JVS - VASCULAR SCIENCE. 2020;1:13-27

Transcriptomic profiling of experimental arterial injury reveals new mechanisms and temporal dynamics in vascular healing response.

Röhl S; Rykaczewska U; Seime T; Suur BE; Diez MG; Gådin JR; Gainullina A; Sergushichev AA; Wirka R; Lengquist M; Kronqvist M; Bergman O; Odeberg J; Lindeman JHN; Quertermous T; Hamsten A; Eriksson P; Hedin U; Razuvaev A; Matic LP
Article: INTERNATIONAL JOURNAL OF NANOMEDICINE. 2020;15:6137-6152

ORIGINAL RESEARCH Molecular Imaging of Inflammation in a Mouse Model of Atherosclerosis Using a Zirconium-89-Labeled Probe

Ahmed M; Tegnebratt T; Tran TA; Damberg P; Gistera A; Tarnawski L; Bone D; Hedin U; Eriksson P; Holmin S; Gustafsson B; Caidahl K
Article: JOURNAL OF INTERNAL MEDICINE. 2020;287(1):66-77

New candidate genes for ST-elevation myocardial infarction

Cederstrom S; Lundman P; Folkersen L; Paulsson-Berne G; Karadimou G; Eriksson P; Caidahl K; Gabrielsen A; Jernberg T; Persson J; Tornvall P
Article: NATURE GENETICS. 2020;52(1):40-47

Loss of ADAMTS19 causes progressive non-syndromic heart valve disease

Wuennemann F; Ta-Shma A; Preuss C; Leclerc S; van Vliet PP; Oneglia A; Thibeault M; Nordquist E; Lincoln J; Scharfenberg F; Becker-Pauly C; Hofmann P; Hoff K; Audain E; Kramer H-H; Makalowski W; Nir A; Gerety SS; Hurles M; Comes J; Fournier A; Osinska H; Robins J; Puceat M; Elpeleg O; Hitz M-P; Andelfinger G; Dietz HC; McCallion AS; Loeys BL; Van Laer L; Eriksson P; Mohamed SA; Mertens L; Franco-Cereceda A; Mital S
Journal article: EUROPEAN JOURNAL OF VASCULAR AND ENDOVASCULAR SURGERY. 2019;58(6):e70-e71

Elastase Fibrinolysis as a Marker of Presence, Size and Mechanical Stress of Abdominal Aortic Aneurysms and its Intraluminal Thrombi

Liljeqvist ML; Hultgren R; Silveira A; Eriksson P; Roy J
Article: JOURNAL OF INTERNAL MEDICINE. 2019;286(6):660-675

Subclinical atherosclerosis and its progression are modulated by PLIN2 through a feed-forward loop between LXR and autophagy

Saliba-Gustafsson P; Pedrelli M; Gertow K; Werngren O; Janas V; Pourteymour S; Baldassarre D; Tremoli E; Veglia F; Rauramaa R; Smit AJ; Giral P; Kurl S; Pirro M; de Faire U; Humphries SE; Hamsten A; Goncalves I; Orho-Melander M; Franco-Cereceda A; Boren J; Eriksson P; Magne J; Parini P; Ehrenborg E; Sirtori CR; Castelnuovo S; Amato M; Frigerio B; Ravani A; Sansaro D; Tedesco C; Bovis F; Discacciati A; Ahl M; Blomgren G; Eriksson MJ; Fahlstadius P; Heinonen M; Nilson L; Cooper J; Acharya J; Huttunen K; Rauramaa E; Pekkarinen H; Penttila IM; Torronen J; van Gessel AI; van Roon AM; Teune GC; Kuipers WD; Bruin M; Nicolai A; Haarsma-Jorritsma P; Mulder DJ; Bilo HJG; Smeets GH; Beaudeux JL; Kahn JF; Carreau V; Kontush A; Karppi J; Nurmi T; Nyyssonen K; Salonen R; Tuomainen TP; Tuomainen J; Kauhanen J; Vaudo G; Alaeddin A; Siepi D; Lupattelli G; Schillaci G
Article: JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY. 2019;137:1-8

Cardiac expression of the microsomal triglyceride transport protein protects the heart function during ischemia

Klevstig M; Arif M; Mannila M; Svedlund S; Mardani I; Stahlman M; Andersson L; Lindbom M; Miljanovic A; Franco-Cereceda A; Eriksson P; Jeppsson A; Gan L-M; Levin M; Mardinoglu A; Ehrenborg E; Boren J
Article: JOURNAL OF THROMBOSIS AND HAEMOSTASIS. 2019;17(11):1808-1814

A Genome Wide Association Study on plasma FV levels identified PLXDC2 as a new modifier of the coagulation process

Thibord F; Hardy L; Ibrahim-Kosta M; Saut N; Pulcrano-Nicolas A-S; Goumidi L; Civelek M; Eriksson P; Deleuze J-F; Le Goff W; Tregouet D-A; Morange P-E
Article: EUROPEAN HEART JOURNAL. 2019;40(30):2495-2503

Prevention of radiotherapy-induced arterial inflammation by interleukin-1 blockade

Christersdottir T; Pirault J; Gistera A; Bergman O; Gallina AL; Baumgartner R; Lundberg AM; Eriksson P; Yan Z-Q; Paulsson-Berne G; Hansson GK; Olofsson PS; Halle M
Article: EUROPEAN JOURNAL OF HUMAN GENETICS. 2019;27(7):1033-1043

Copy number variation analysis in bicuspid aortic valve-related aortopathy identifies TBX20 as a contributing gene

Luyckx I; Kumar AA; Reyniers E; Dekeyser E; Vanderstraeten K; Vandeweyer G; Wunnemann F; Preuss C; Mazzella J-M; Goudot G; Messas E; Albuisson J; Jeunemaitre X; Eriksson P; Mohamed SA; Kempers M; Salemink S; Duijnhouwer A; Andelfinger G; Dietz HC; Verstraeten A; Van Laer L; Loeys BL; Zhurayev R; Zerbino D; Mital S; Mertens L; Franco-Cereceda A; Verhagen JMA; van de Laar IMBH; Wessels MW; Nemcikova M; Krebsova A
Article: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2019;20(6):E1486-1486

Upregulated Autophagy in Calcific Aortic Valve Stenosis Confers Protection of Valvular Interstitial Cells

Carracedo M; Persson O; Saliba-Gustafsson P; Artiach G; Ehrenborg E; Eriksson P; Franco-Cereceda A; Back M
Article: CIRCULATION-GENOMIC AND PRECISION MEDICINE. 2019;12(3):e002353

High-Resolution Regulatory Maps Connect Vascular Risk Variants to Disease-Related Pathways

Akerborg O; Spalinskas R; Pradhananga S; Anil A; Hojer P; Poujade F-A; Folkersen L; Sahlen P; Eriksson PP
Article: INTERNATIONAL JOURNAL OF CARDIOLOGY. 2019;278:65-69

Comparison of biomechanical properties in ascending aortic aneurysms of patients with congenital bicuspid aortic valve and Marfan syndrome

Yan J; Lehsau A-C; Sauer B; Pieper B; Mohamed SA; Loeys BL; Dietz HC; Van Laer L; McCallion AS; Eriksson P; Franco-Cereceda A; Mertens L; Mital S; Andelfinger G; Mohamed SAC
Article: INTERNATIONAL JOURNAL OF CARDIOLOGY. 2019;276:212-217

Effects of the coronary artery disease associated LPA and 9p21 loci on risk of aortic valve stenosis

Trenkwalder T; Nelson CP; Musameh MD; Mordi IR; Kessler T; Pellegrini C; Debiec R; Rheude T; Lazovic V; Zeng L; Martinsson A; Smith JG; Gadin JR; Franco-Cereceda A; Eriksson P; Nielsen JB; Graham SE; Willer CJ; Hveem K; Kastrati A; Braund PS; Palmer CNA; Aracil A; Husser O; Koenig W; Schunkert H; Lang CC; Hengstenberg C; Samani NJ
Article: PLOS ONE. 2019;14(6):e0217765

Comparison of quantitative trait loci methods: Total expression and allelic imbalance method in brain RNA-seq

Gadin JR; Buil A; Colantuoni C; Jaffe AE; Nielsen J; Shin J-H; Hyde TM; Kleinman JE; Plath N; Eriksson P; Brunak S; Didriksen M; Weinberger DR; Folkersen L; Hoeppner D; Matsumoto M; Saito T; Tajinda K; Brandon NJ; Alan; Airey DC; Calley JN; Collier DA; Eastwood BJ; Ebert PJ; Li Y; Liu Y; Malki K; Miller BB; Ruble CLA; Scherschel JE; Wang H; Furey M; Hibar D; Kolb H; Jaffe AE; Shin JH; Straub RE; Weinberger DR; Didriksen M; Folkersen L; Quan J; Xi S; Tony K-T; Malhotra D
Article: JOURNAL OF INTERNAL MEDICINE. 2019;285(1):102-114

The mir-200 family regulates key pathogenic events in ascending aortas of individuals with bicuspid aortic valves

Maleki S; Cottrill KA; Poujade F-A; Bhattachariya A; Bergman O; Gadin JR; Simon N; Lundstromer K; Franco-Cereceda A; Bjorck HM; Chan SY; Eriksson P
Article: NATURE GENETICS. 2019;51(1):42-50

ROBO4 variants predispose individuals to bicuspid aortic valve and thoracic aortic aneurysm

Gould RA; Aziz H; Woods CE; Seman-Senderos MA; Sparks E; Preuss C; Wunnemann F; Bedja D; Moats CR; McClymont SA; Rose R; Sobreira N; Ling H; MacCarrick G; Kumar AA; Luyckx I; Cannaerts E; Verstraeten A; Bjork HM; Lehsau A-C; Jaskula-Ranga V; Lauridsen H; Shah AA; Bennett CL; Ellinor PT; Lin H; Isselbacher EM; Cardenas CLL; Butcher JT; Hughes GC; Lindsay ME; Mertens L; Franco-Cereceda A; Verhagen JMA; Wessels M; Mohamed SA; Eriksson P; Mital S; Van Laer L; Loeys BL; Andelfinger G; McCallion AS; Dietz HC; Valle D; Lupski J
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DNA methylation age is associated with an altered hemostatic profile in a multiethnic meta-analysis

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H19 Induces Abdominal Aortic Aneurysm Development and Progression

Li DY; Busch A; Jin H; Chernogubova E; Pelisek J; Karlsson J; Sennblad B; Liu S; Lao S; Hofmann P; Baecklund A; Eken SM; Roy J; Eriksson P; Dacken B; Ramanujam D; Dueck A; Engelhardt S; Boon RA; Eckstein H-H; Spin JM; Tsao PS; Maegdefessel L
Article: MOLECULAR THERAPY-METHODS & CLINICAL DEVELOPMENT. 2018;10:17-28

Integrated Human Evaluation of the Lysophosphatidic Acid Pathway as a Novel Therapeutic Target in Atherosclerosis

Aldi S; Matic LP; Hamm G; van Keulen D; Tempel D; Holmstrom K; Szwajda A; Nielsen BS; Emilsson V; Ait-Belkacem R; Lengquist M; Paulsson-Berne G; Eriksson P; Lindeman JHN; Gool AJ; Stauber J; Hedin U; Hurt-Camejo E
Article: ATHEROSCLEROSIS SUPPLEMENTS. 2018;35:e6-e13

Notch, BMP and WNT/β-catenin network is impaired in endothelial cells of the patients with thoracic aortic aneurysm

Kostina A; Bjork H; Ignatieva E; Irtyuga O; Uspensky V; Semenova D; Maleki S; Tomilin A; Moiseeva O; Franco-Cereceda A; Gordeev M; Faggian G; Kostareva A; Eriksson P; Malashicheva A
Article: NATURE COMMUNICATIONS. 2018;9(1):987

Genome-wide analysis yields new loci associating with aortic valve stenosis

Helgadottir A; Thorleifsson G; Gretarsdottir S; Stefansson OA; Tragante V; Thorolfsdottir RB; Jonsdottir I; Bjornsson T; Steinthorsdottir V; Verweij N; Nielsen JB; Zhou W; Folkersen L; Martinsson A; Heydarpour M; Prakash S; Oskarsson G; Gudbjartsson T; Geirsson A; Olafsson I; Sigurdsson EL; Almgren P; Melander O; Franco-Cereceda A; Hamsten A; Fritsche L; Lin M; Yang B; Hornsby W; Guo D; Brummett CM; Abecasis G; Mathis M; Milewicz D; Body SC; Eriksson P; Willer CJ; Hveem K; Newton-Cheh C; Smith JG; Danielsen R; Thorgeirsson G; Thorsteinsdottir U; Gudbjartsson DF; Holm H; Stefansson K
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Cysteinyl leukotriene receptor 1 antagonism prevents experimental abdominal aortic aneurysm

Di Gennaro A; Araujo AC; Busch A; Jin H; Wagsater D; Vorkapic E; Caidahl K; Eriksson P; Samuelsson B; Maegdefessel L; Haeggstrom JZ
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Altered DNA methylation indicates an oscillatory flow mediated epithelial-to-mesenchymal transition signature in ascending aorta of patients with bicuspid aortic valve

Bjorck HM; Du L; Pulignani S; Paloschi V; Lundstromer K; Kostina AS; Osterholm C; Malashicheva A; Kostareva A; Evangelista A; Teixido-Tura G; Maleki S; Franco-Cereceda A; Eriksson P
Article: THROMBOSIS AND HAEMOSTASIS. 2018;118(2):329-339

Neutrophil Elastase-Derived Fibrin Degradation Products Indicate Presence of Abdominal Aortic Aneurysms and Correlate with Intraluminal Thrombus Volume

Liljeqvist ML; Silveira A; Hultgren R; Frebelius S; Lengquist M; Engstrom J; Gasser TC; Eriksson P; Roy J
Article: JOURNAL OF INTERNAL MEDICINE. 2017;282(5):429-444

Integrative studies implicate matrix metalloproteinase-12 as a culprit gene for large-artery atherosclerotic stroke

Mahdessian H; Matic LP; Lengquist M; Gertow K; Sennblad B; Baldassarre D; Veglia F; Humphries SE; Rauramaa R; de Faire U; Smit AJ; Giral P; Kurl S; Mannarino E; Tremoli E; Hamsten A; Eriksson P; Hedin U; Malarstig A
Article: KIDNEY INTERNATIONAL REPORTS. 2017;2(6):1208-1218

Altered Protein Composition of Subcutaneous Adipose Tissue in Chronic Kidney Disease

Gertow J; Ng CZ; Branca RMM; Werngren O; Du L; Kjellqvist S; Hemmingsson P; Bruchfeld A; MacLaughlin H; Eriksson P; Axelsson J; Fisher RM
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ClusterSignificance: a bioconductor package facilitating statistical analysis of class cluster separations in dimensionality reduced data

Serviss JT; Gadin JR; Eriksson P; Folkersen L; Grander D
Article: HISTOCHEMISTRY AND CELL BIOLOGY. 2017;148(4):425-433

Vessel wall morphology is equivalent for different artery types and localizations of advanced human aneurysms

Busch A; Grimm C; Hartmann E; Paloschi V; Kickuth R; Lengquist M; Otto C; Eriksson P; Kellersmann R; Lorenz U; Maegdefessel L
Article: JOURNAL OF VASCULAR SURGERY. 2017;66(2):579-585.e1

The composition of collagen in the aneurysm wall of men and women

Villard C; Eriksson P; Hanemaaijer R; Lindeman JH; Hultgren R
Article: NATURE COMMUNICATIONS. 2017;8:15481

Protein-altering and regulatory genetic variants near GATA4 implicated in bicuspid aortic valve

Yang B; Zhou W; Jiao J; Nielsen JB; Mathis MR; Heydarpour M; Lettre G; Folkersen L; Prakash S; Schurmann C; Fritsche L; Farnum GA; Lin M; Othman M; Hornsby W; Driscoll A; Levasseur A; Thomas M; Farhat L; Dube M-P; Isselbacher EM; Franco-Cereceda A; Guo D-C; Bottinger EP; Deeb GM; Booher A; Kheterpal S; Chen YE; Kang HM; Kitzman J; Cordell HJ; Keavney BD; Goodship JA; Ganesh SK; Abecasis G; Eagle KA; Boyle AP; Loos RJF; Eriksson P; Tardif J-C; Brummett CM; Milewicz DM; Body SC; Willer CJ
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Mapping of 79 loci for 83 plasma protein biomarkers in cardiovascular disease

Folkersen L; Fauman E; Sabater-Lleal M; Strawbridge RJ; Franberg M; Sennblad B; Baldassarre D; Veglia F; Humphries SE; Rauramaa R; de Faire U; Smit AJ; Giral P; Kurl S; Mannarino E; Enroth S; Johansson A; Enroth SB; Gustafsson S; Lind L; Lindgren C; Morris AP; Giedraitis V; Silveira A; Franco-Cereceda A; Tremoli E; Gyllensten U; Ingelsson E; Brunak S; Eriksson P; Ziemek D; Hamsten A; Malarstig A
Article: CIRCULATION RESEARCH. 2017;120(4):633-644

MicroRNA-210 Enhances Fibrous Cap Stability in Advanced Atherosclerotic Lesions

Eken SM; Jin H; Chernogubova E; Li Y; Simon N; Sun C; Korzunowicz G; Busch A; Backlund A; Osterholm C; Razuvaev A; Renne T; Eckstein HH; Pelisek J; Eriksson P; Diez MG; Matic LP; Schellinger IN; Raaz U; Leeper NJ; Hansson GK; Paulsson-Berne G; Hedin U; Maegdefessel L
Article: HUMAN MOLECULAR GENETICS. 2017;26(3):637-649

Genome- wide association study with additional genetic and post-transcriptional analyses reveals novel regulators of plasma factor XI levels

Sennblad B; Basu S; Mazur J; Suchon P; Martinez-Perez A; Vlieg AVH; Vinh T; Li Y; Gadin JR; Tang W; Grossman V; de Haan HG; Handin N; Silveira A; Carlos Souto J; Franco-Cereceda A; Morange P-E; Gagnon F; Manuel Soria J; Eriksson P; Hamsten A; Maegdefessel L; Rosendaal FR; Wild P; Folsom AR; Tregouet D-A; Sabater-Lleal M
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Differential expression of sex hormone receptors in abdominal aortic aneurysms

Villard C; Eriksson P; Kronqvist M; Lengquist M; Jorns C; Hartman J; Roy J; Hultgren R
Article: CIRCULATION RESEARCH. 2017;120(2):341-353

Meta-Analysis of Genome-Wide Association Studies for Abdominal Aortic Aneurysm Identifies Four New Disease-Specific Risk Loci

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Elevated circulating fasting glucagon-like peptide-1 in surgical patients with aortic valve disease and diabetes

Krizhanovskii C; Ntika S; Olsson C; Eriksson P; Franco-Cereceda A
Article: FRONTIERS IN PHYSIOLOGY. 2017;8:400

Candidate Gene Resequencing in a Large Bicuspid Aortic Valve-Associated Thoracic Aortic Aneurysm Cohort: SMAD6 as an Important Contributor

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Functional Analysis of the Coronary Heart Disease Risk Locus on Chromosome 21q22

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Iron alters valvular interstitial cell function and is associated with calcification in aortic stenosis

Laguna-Fernandez A; Carracedo M; Jeanson G; Nagy E; Eriksson P; Caligiuri G; Franco-Cereceda A; Back M
Article: SCIENTIFIC REPORTS. 2016;6:35712

Mesenchymal state of intimal cells may explain higher propensity to ascending aortic aneurysm in bicuspid aortic valves

Maleki S; Kjellqvist S; Paloschi V; Magne J; Branca RMM; Du L; Hultenby K; Petrini J; Fuxe J; Lehtio J; Franco-Cereceda A; Eriksson P; Bjorck HM
Article: NATURE GENETICS. 2016;48(10):1171-1184

The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals

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Article: NATURE MEDICINE. 2016;22(10):1140-1150

Adenosine-to-inosine RNA editing controls cathepsin S expression in atherosclerosis by enabling HuR-mediated post-transcriptional regulation

Stellos K; Gatsiou A; Stamatelopoulos K; Matic LP; John D; Lunella FF; Jae N; Rossbach O; Amrhein C; Sigala F; Boon RA; Fuertig B; Manavski Y; You X; Uchida S; Keller T; Boeckel J-N; Franco-Cereceda A; Maegdefessel L; Chen W; Schwalbe H; Bindereif A; Eriksson P; Hedin U; Zeiher AM; Dimmeler S
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Elevated Adiponectin Levels Suppress Perivascular and Aortic Inflammation and Prevent AngII-induced Advanced Abdominal Aortic Aneurysms

Wagsater D; Vorkapic E; van Stijn CMW; Kim J; Lusis AJ; Eriksson P; Tangirala RK
Article: INTERNATIONAL JOURNAL OF CARDIOLOGY. 2016;219:446-454

Perilipin 5 is protective in the ischemic heart

Drevinge C; Dalen KT; Mannila MN; Tang MS; Stahlman M; Klevstig M; Lundqvist A; Mardani I; Haugen F; Fogelstrand P; Adiels M; Asin-Cayuela J; Ekestam C; Gadin JR; Lee YK; Nebb H; Svedlund S; Johansson BR; Hulten LM; Romeo S; Redfors B; Omerovic E; Levin M; Gan L-M; Eriksson P; Andersson L; Ehrenborg E; Kimmel AR; Boren J; Levin MC
Article: AMERICAN JOURNAL OF HUMAN GENETICS. 2016;99(3):762-769

Genetic Variants in LRP1 and ULK4 Are Associated with Acute Aortic Dissections

Guo D-C; Grove ML; Prakash SK; Eriksson P; Hostetler EM; LeMaire SA; Body SC; Shalhub S; Estrera AL; Safi HJ; Regalado ES; Zhou W; Mathis MR; Eagle KA; Yang B; Willer CJ; Boerwinkle E; Milewicz DM
Article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2016;36(9):1947-1961

Phenotypic Modulation of Smooth Muscle Cells in Atherosclerosis Is Associated With Downregulation of LMOD1, SYNPO2, PDLIM7, PLN, and SYNM

Matic LP; Rykaczewska U; Razuvaev A; Sabater-Lleal M; Lengquist M; Miller CL; Ericsson I; Rohl S; Kronqvist M; Aldi S; Magne J; Paloschi V; Vesterlund M; Li Y; Jin H; Diez MG; Roy J; Baldassarre D; Veglia F; Humphries SE; de Faire U; Tremoli E; Odeberg J; Vukojevic V; Lehtio J; Maegdefessel L; Ehrenborg E; Paulsson-Berne G; Hansson GK; Lindeman JHN; Eriksson P; Quertermous T; Hamsten A; Hedin U
Article: IJC HEART AND VASCULATURE. 2016;11:74-79

Intima-media thickness of the descending aorta in patients with bicuspid aortic valve.

Petrini J; Yousry M; Eriksson P; Björk HM; Rickenlund A; Franco-Cereceda A; Caidahl K; Eriksson MJ
Article: ATHEROSCLEROSIS. 2016;249:101-109

Imatinib treatment attenuates growth and inflammation of angiotensin II induced abdominal aortic aneurysm

Vorkapic E; Dugic E; Vikingsson S; Roy J; Mayranpaa MI; Eriksson P; Wagsater D
Article: JOURNAL OF THE AMERICAN HEART ASSOCIATION. 2016;5(5):e003031

NLRP3 Inflammasome Expression and Activation in Human Atherosclerosis

Varghese GP; Folkersen L; Strawbridge RJ; Halvorsen B; Yndestad A; Ranheim T; Krohg-Sorensen K; Skjelland M; Espevik T; Aukrust P; Lengquist M; Hedin U; Jansson J-H; Fransen K; Hansson GK; Eriksson P; Sirsjo A
Article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2016;36(5):972-983

Functional Analysis of a Novel Genome-Wide Association Study Signal in SMAD3 That Confers Protection From Coronary Artery Disease

Turner AW; Martinuk A; Silva A; Lau P; Nikpay M; Eriksson P; Folkersen L; Perisic L; Hedin U; Soubeyrand S; McPherson R
Article: THROMBOSIS AND HAEMOSTASIS. 2015;114(6):1165-1174

Proteolytically active ADAM10 and ADAM17 carried on membrane microvesicles in human abdominal aortic aneurysms

Folkesson M; Li C; Frebelius S; Swedenborg J; Wagsater D; Williams KJ; Eriksson P; Roy J; Liu M-L
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A deleterious gene-by-environment interaction imposed by calcium channel blockers in Marfan syndrome

Doyle JJ; Doyle AJ; Wilson NK; Habashi JP; Bedja D; Whitworth RE; Lindsay ME; Schoenhoff F; Myers L; Huso N; Bachir S; Squires O; Rusholme B; Ehsan H; Huso D; Thomas CJ; Caulfield MJ; Van Eyk JE; Judge DP; Dietz HC
Article: PLOS GENETICS. 2015;11(9):e1005502

Discovering Genetic Interactions in Large-Scale Association Studies by Stage-wise Likelihood Ratio Tests

Franberg M; Gertow K; Hamsten A; Lagergren J; Sennblad B
Article: ATHEROSCLEROSIS. 2015;241(2):561-568

TRIF adaptor signaling is important in abdominal aortic aneurysm formation

Vorkapic E; Lundberg AM; Mayranpaa MI; Eriksson P; Wagsater D
Article: CLINICAL PHYSIOLOGY AND FUNCTIONAL IMAGING. 2015;35(4):306-313

Aortic valve type and calcification as assessed by transthoracic and transoesophageal echocardiography

Yousry M; Rickenlund A; Petrini J; Jenner J; Liska J; Eriksson P; Franco-Cereceda A; Eriksson MJ; Caidahl K
Article: BMC BIOINFORMATICS. 2015;16(1):194

AllelicImbalance: an R/bioconductor package for detecting, managing, and visualizing allele expression imbalance data from RNA sequencing

Gadin JR; van't Hooft FM; Eriksson P; Folkersen L
Journal article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2015;35(suppl_1)

Abstract 261: Neutrophil Elastase Derived Fibrin Degradation Products are Increased in the Plasma of Patients with Abdominal Aortic Aneurysms and Correlate to the Intraluminal Thrombus Volume

Roy J; Silveira A; Liljeqvist Lindquist M; Folkesson M; Frebelius S; Hultgren R; Engstrom J; Swedenborg J; Eriksson P
Article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2015;35(5):1226-1235

ATG16L1 Expression in Carotid Atherosclerotic Plaques Is Associated With Plaque Vulnerability

Magne J; Gustafsson P; Jin H; Maegdefessel L; Hultenby K; Wernerson A; Eriksson P; Franco-Cereceda A; Kovanen PT; Goncalves I; Ehrenborg E
Journal article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2015;35(suppl_1)

Abstract 267: CD93: A Novel Myocardial Infarction- Associated Protein with Glucose Regulatory Properties in Humans and Mice

Bäcklund A; Strawbridge R; Jin HJ; Tsikrika P; Silveira A; Ketelhuth DF; Eriksson P; Maegdefessel L; Hamsten A
Article: NEW ENGLAND JOURNAL OF MEDICINE. 2015;372(17):1608-1618

Genetically Determined Height and Coronary Artery Disease

Nelson CP; Hamby SE; Saleheen D; Hopewell JC; Zeng L; Assimes TL; Kanoni S; Willenborg C; Burgess S; Amouyel P; Anand S; Blankenberg S; Boehm BO; Clarke RJ; Collins R; Dedoussis G; Farrall M; Franks PW; Groop L; Hall AS; Hamsten A; Hengstenberg C; Hovingh GK; Ingelsson E; Kathiresan S; Kee F; Koenig IR; Kooner J; Lehtimaeki T; Maerz W; McPherson R; Metspalu A; Nieminen MS; O'Donnell CJ; Palmer CNA; Peters A; Perola M; Reilly MP; Ripatti S; Roberts R; Salomaa V; Shah SH; Schreiber S; Siegbahn A; Thorsteinsdottir U; Veronesi G; Wareham N; Willer CJ; Zalloua PA; Erdmann J; Deloukas P; Watkins H; Schunkert H; Danesh J; Thompson JR; Samani NJ
Article: AMERICAN JOURNAL OF HUMAN GENETICS. 2015;96(4):532-542

Meta-analysis of 65,734 Individuals Identifies TSPAN15 and SLC44A2 as Two Susceptibility Loci for Venous Thromboembolism

Germain M; Chasman DI; de Haan H; Tang W; Lindstroem S; Weng L-C; de Andrade M; de Visser MCH; Wiggins KL; Suchon P; Saut N; Smadja DM; Le Gal G; Vlieg AVH; Di Narzo A; Hao K; Nelson CP; Rocanin-Arjo A; Folkersen L; Monajemi R; Rose LM; Brody JA; Slagboom E; Aissi D; Gagnon F; Deleuze J-F; Deloukas P; Tzourio C; Dartigues J-F; Berr C; Taylor KD; Civelek M; Eriksson P; Psaty BM; Houwing-Duitermaat J; Goodall AH; Cambien F; Kraft P; Amouyel P; Samani NJ; Basu S; Ridker PM; Rosendaal FR; Kabrhel C; Folsom AR; Heit J; Reitsma PH; Tregouet D-A; Smith NL; Morange P-E
Article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2015;35(4):973-980

Aneurysm Development in Patients With a Bicuspid Aortic Valve Is Not Associated With Transforming Growth Factor-β Activation

Paloschi V; Gadin JR; Khan S; Bjorck HM; Du L; Maleki S; Roy J; Lindeman JHM; Mohamed SA; Tsuda T; Franco-Cereceda A; Eriksson P
Article: CIRCULATION-GENOMIC AND PRECISION MEDICINE. 2015;8(2):356-362

PLA2G10 Gene Variants, sPLA2 Activity, and Coronary Heart Disease Risk

Guardiola M; Exeter HJ; Perret C; Folkersen L; van't Hooft F; Eriksson P; Franco-Cereceda A; Paulsson-Berne G; Palmen J; Li K; Cooper JA; Khaw K-T; Mallat Z; Ninio E; Karabina S-A; Humphries SE; Boekholdt SM; Holmes MV; Talmud PJ
Article: CIRCULATION RESEARCH. 2015;116(4):642-652

Increased Arterial Blood Pressure and Vascular Remodeling in Mice Lacking Salt-Inducible Kinase 1 (SIK1)

Bertorello AM; Pires N; Igreja B; Pinho MJ; Vorkapic E; Wagsater D; Wikstrom J; Behrendt M; Hamsten A; Eriksson P; Soares-da-Silva P; Brion L
Article: NATURE. 2015;518(7538):197-206

Genetic studies of body mass index yield new insights for obesity biology

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Article: NATURE. 2015;518(7538):187-196

New genetic loci link adipose and insulin biology to body fat distribution

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Article: JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY. 2014;148(6):2973-80.e1

Ascending aortic dilatation is rarely associated with coronary artery disease regardless of aortic valve morphology

Jackson V; Eriksson MJ; Caidahl K; Eriksson P; Franco-Cereceda A
Article: NATURE COMMUNICATIONS. 2014;5:5214

miR-24 limits aortic vascular inflammation and murine abdominal aneurysm development

Maegdefessel L; Spin JM; Raaz U; Eken SM; Toh R; Azuma J; Adam M; Nagakami F; Heymann HM; Chernugobova E; Jin H; Roy J; Hultgren R; Caidahl K; Schrepfer S; Hamsten A; Eriksson P; McConnell MV; Dalman RL; Tsao PS
Article: AORTA. 2014;2(5):179-185

Differences in Elastin and Elastolytic Enzymes between Men and Women with Abdominal Aortic Aneurysm.

Villard C; Eriksson P; Swedenborg J; Hultgren R
Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 2014;44(10):3081-3092

Innate immune receptor NOD2 promotes vascular inflammation and formation of lipid-rich necrotic cores in hypercholesterolemic mice

Johansson ME; Zhang X-Y; Edfeldt K; Lundberg AM; Levin MC; Boren J; Li W; Yuan X-M; Folkersen L; Eriksson P; Hedin U; Low H; Sviridov D; Rios FJ; Hansson GK; Yan Z-Q
Article: JOURNAL OF THE AMERICAN HEART ASSOCIATION. 2014;3(4):e001040

Association Between Thoracic Aortic Disease and Inguinal Hernia

Olsson C; Eriksson P; Franco-Cereceda A
Article: BMJ-BRITISH MEDICAL JOURNAL. 2014;349:g4164

Association between alcohol and cardiovascular disease: Mendelian randomisation analysis based on individual participant data

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Article: ANNALS OF THORACIC SURGERY. 2014;98(1):65-71

Biomechanical Properties of the Thoracic Aneurysmal Wall: Differences Between Bicuspid Aortic Valve and Tricuspid Aortic Valve Patients

Forsell C; Bjorck HM; Eriksson P; Franco-Cereceda A; Gasser TC
Article: JOURNAL OF HEART VALVE DISEASE. 2014;23(4):463-472

Aortic Dimensions in Relation to Bicuspid and Tricuspid Aortic Valve Pathology

Jackson V; Petrini J; Eriksson MJ; Caidahl K; Eriksson P; Franco-Cereceda A
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2014;111(24):8913-8918

TM6SF2 is a regulator of liver fat metabolism influencing triglyceride secretion and hepatic lipid droplet content

Mahdessian H; Taxiarchis A; Popov S; Silveira A; Franco-Cereceda A; Hamsten A; Eriksson P; van't Hooft F
Article: DIABETOLOGIA. 2014;57(6):1159-1172

A serum 25-hydroxyvitamin D concentration-associated genetic variant in DHCR7 interacts with type 2 diabetes status to influence subclinical atherosclerosis (measured by carotid intima-media thickness)

Strawbridge RJ; Deleskog A; McLeod O; Folkersen L; Kavousi M; Gertow K; Baldassarre D; Veglia F; Leander K; Gigante B; Kauhanen J; Rauramaa R; Smit AJ; Mannarino E; Giral P; Dehghan A; Hofman A; Franco OH; Humphries SE; Tremoli E; de Faire U; Gustafsson S; Ostensson C-G; Eriksson P; Ohrvik J; Hamsten A
Article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2014;34(5):1093-1101

Genome-Wide Association Study for Circulating Tissue Plasminogen Activator Levels and Functional Follow-Up Implicates Endothelial STXBP5 and STX2

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Article: CIRCULATION-GENOMIC AND PRECISION MEDICINE. 2014;7(2):144-150

Novel Genetic Approach to Investigate the Role of Plasma Secretory Phospholipase A2 (sPLA₂)-V Isoenzyme in Coronary Heart Disease Modified Mendelian Randomization Analysis Using PLA2G5 Expression Levels

Holmes MV; Exeter HJ; Folkersen L; Nelson CP; Guardiola M; Cooper JA; Sofat R; Boekholdt SM; Khaw K-T; Li K-W; Smith AJP; van't Hooft F; Eriksson P; Franco-Cereceda A; Asselbergs FW; Boer JMA; Onland-Moret NC; Hofker M; Erdmann J; Kivimaki M; Kumari M; Reiner AP; Keating BJ; Humphries SE; Hingorani AD; Mallat Z; Samani NJ; Talmud PJ
Article: JOURNAL OF THE AMERICAN SOCIETY OF ECHOCARDIOGRAPHY. 2014;27(4):393-404

Elastic Properties of the Descending Aorta in Patients with a Bicuspid or Tricuspid Aortic Valve and Aortic Valvular Disease

Petrini J; Jenner J; Rickenlund A; Eriksson P; Franco-Cereceda A; Caidahl K; Eriksson MJ
Article: NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES. 2014;24(2):124-131

Ceramides are associated with inflammatory processes in human mediastinal adipose tissue

Gertow J; Kjellqvist S; Stahlman M; Cheung L; Gottfries J; Werngren O; Boren J; Franco-Cereceda A; Eriksson P; Fisher RM
Article: PLOS ONE. 2014;9(4):e95771

Lack of Salt-Inducible Kinase 2 (SIK2) Prevents the Development of Cardiac Hypertrophy in Response to Chronic High-Salt Intake

Popov S; Takemori H; Tokudome T; Mao Y; Otani K; Mochizuki N; Pires N; Pinho MJ; Franco-Cereceda A; Torielli L; Ferrandi M; Hamsten A; Soares-da-Silva P; Eriksson P; Bertorello AM; Brion L
Article: PLOS ONE. 2014;9(8):e104082

Common Genetic Determinants of Lung Function, Subclinical Atherosclerosis and Risk of Coronary Artery Disease

Sabater-Lleal M; Maelarstig A; Folkersen L; Artigas MS; Baldassarre D; Kavousi M; Almgren P; Veglia F; Brusselle G; Hofman A; Engstrom G; Franco OH; Melander O; Paulsson-Berne G; Watkins H; Eriksson P; Humphries SE; Tremoli E; de Faire U; Tobin MD; Hamsten A
Article: EUROPEAN HEART JOURNAL. 2013;34(48):3707-3716

Interleukin-6 receptor pathways in abdominal aortic aneurysm

Harrison SC; Smith AJP; Jones GT; Swerdlow DI; Rampuri R; Bown MJ; Folkersen L; Baas AF; de Borst GJ; Blankensteijn JD; Price JF; van der Graaf Y; McLachlan S; Agu O; Hofman A; Uitterlinden AG; Franco-Cereceda A; Ruigrok YM; van't Hof FN; Powell JT; van Rij AM; Casas JP; Eriksson P; Holmes MV; Asselbergs FW; Hingorani AD; Humphries SE
Journal article: CIRCULATION. 2013;128(suppl_22)

Abstract 18975: Increased Arterial Blood Pressure and Vascular Fibrosis/remodeling in Mice Lacking Salt-inducible Kinase 1 (sik1)

Brion L; Pires N; Igreja B; Pinho MJ; Wågsäter D; Wikström J; Behrendt M; Hamsten A; Eriksson P; Soares-da-Silva P; Bertorello AM
Article: JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY. 2013;62(21):1966-1976

Secretory Phospholipase A₂-IIA and Cardiovascular Disease

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Article: MOLECULAR & CELLULAR PROTEOMICS. 2013;12(11):3398-3408

Network-based Analysis of Genome Wide Association Data Provides Novel Candidate Genes for Lipid and Lipoprotein Traits

Sharma A; Gulbahce N; Pevzner SJ; Menche J; Ladenvall C; Folkersen L; Eriksson P; Orho-Melander M; Barabasi A-L
Article: INTERNATIONAL JOURNAL OF CARDIOLOGY. 2013;168(3):2264-2271

Valvular osteoclasts in calcification and aortic valve stenosis severity

Nagy E; Eriksson P; Yousry M; Caidahl K; Ingelsson E; Hansson GK; Franco-Cereceda A; Back M
Article: CIRCULATION-GENOMIC AND PRECISION MEDICINE. 2013;6(5):498-504

A Variant in LDLR Is Associated With Abdominal Aortic Aneurysm

Bradley DT; Hughes AE; Badger SA; Jones GT; Harrison SC; Wright BJ; Bumpstead S; Baas AF; Gretarsdottir S; Burnand K; Child AH; Clough RE; Cockerill G; Hafez H; Scott DJA; Ariens RAS; Johnson A; Sohrabi S; Smith A; Thompson MM; van Bockxmeer FM; Waltham M; Matthiasson SE; Thorleifsson G; Thorsteinsdottir U; Blankensteijn JD; Teijink JAW; Wijmenga C; de Graaf J; Kiemeney LA; Wild JB; Edkins S; Gwilliam R; Hunt SE; Potter S; Lindholt JS; Golledge J; Norman PE; van Rij A; Powell JT; Eriksson P; Stefansson K; Thompson JR; Humphries SE; Sayers RD; Deloukas P; Samani NJ; Bown MJ
Article: CIRCULATION. 2013;128(12):1310-1324

Multiethnic Meta-Analysis of Genome-Wide Association Studies in > 100 000 Subjects Identifies 23 FibrinogenAssociated Loci but No Strong Evidence of a Causal Association Between Circulating Fibrinogen and Cardiovascular Disease

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Article: JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY. 2013;146(3):605-610

Aortic dimensions in patients with bicuspid and tricuspid aortic valves

Jackson V; Olsson C; Eriksson P; Franco-Cereceda A
Journal article: EUROPEAN HEART JOURNAL. 2013;34(suppl_1):p394

Array-based profiling reveals biomarker and therapeutic potential for different microRNAs in patients with symptomatic carotid stenosis

Eken SM; Osterholm C; Chernogubova E; Jin H; Razuvajev A; Perisic L; Hedin U; Roy J; Eriksson P; Maegdefessel L
Journal article: EUROPEAN HEART JOURNAL. 2013;34(suppl_1):5937

MicroRNAs are novel plasma biomarkers for diagnosis and prognosis of abdominal aortic aneurysm disease

Eken SM; Chernogubova E; Jin H; Roy J; Hamsten A; Eriksson P; Tsao PS; Maegdefessel L
Article: JOURNAL OF VASCULAR SURGERY. 2013;58(2):333-339.e1

Mortality and reoperations in survivors operated on for acute type A aortic dissection and implications for catheter-based or hybrid interventions

Olsson C; Hillebrant C-G; Liska J; Lockowandt U; Eriksson P; Franco-Cereceda A
Article: AORTA. 2013;1(1):13-22

Aneurysm Development in Patients With Bicuspid Aortic Valve (BAV): Possible Connection to Repair Deficiency?

Maleki S; Björck HM; Paloschi V; Kjellqvist S; Folkersen L; Jackson V; Franco-Cereceda A; Eriksson P
Article: NUTRITION & DIABETES. 2013;3(5):e66

Human mediastinal adipose tissue displays certain characteristics of brown fat

Cheung L; Gertow J; Werngren O; Folkersen L; Petrovic N; Nedergaard J; Franco-Cereceda A; Eriksson P; Fisher RM
Article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2013;33(5):1063-1069

Identification of a Functional Apolipoprotein E Promoter Polymorphism Regulating Plasma Apolipoprotein E Concentration

Mannila MN; Mahdessian H; Franco-Cereceda A; Eggertsen G; de Faire U; Syvanen A-C; Eriksson P; Hamsten A; van 't Hooft FM
Article: JOURNAL OF THE AMERICAN HEART ASSOCIATION. 2013;2(1):e000034

Impaired Collagen Biosynthesis and Cross-linking in Aorta of Patients With Bicuspid Aortic Valve

Wagsater D; Paloschi V; Hanemaaijer R; Hultenby K; Bank RA; Franco-Cereceda A; Lindeman JHN; Eriksson P
Article: ATHEROSCLEROSIS. 2013;226(2):440-446

A gene-centric study of common carotid artery remodelling

Harrison SC; Zabaneh D; Asselbergs FW; Drenos F; Jones GT; Shah S; Gertow K; Sennblad B; Strawbridge RJ; Gigante B; Holewijn S; De Graaf J; Vermeulen S; Folkersen L; van Rij AM; Baldassarre D; Veglia F; Talmud PJ; Deanfield JE; Agu O; Kivimaki M; Kumari M; Bown MJ; Nyyssonen K; Rauramaa R; Smit AJ; Franco-Cereceda A; Giral P; Mannarino E; Silveira A; Syvanen A-C; de Borst GJ; van der Graaf Y; de Faire U; Baas AF; Blankensteijn JD; Wareham NJ; Fowkes G; Tzoulaki I; Price JF; Tremoli E; Hingorani AD; Eriksson P; Hamsten A; Humphries SE
Article: MOLECULAR & CELLULAR PROTEOMICS. 2013;12(2):407-425

A Combined Proteomic and Transcriptomic Approach Shows Diverging Molecular Mechanisms in Thoracic Aortic Aneurysm Development in Patients with Tricuspid- And Bicuspid Aortic Valve

Kjellqvist S; Maleki S; Olsson T; Chwastyniak M; Branca RMM; Lehtio J; Pinet F; Franco-Cereceda A; Eriksson P
Article: NATURE GENETICS. 2013;45(1):25-33

Large-scale association analysis identifies new risk loci for coronary artery disease.

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Journal article: NATURE GENETICS. 2013;45(1):25-U52

Large-scale association analysis identifies new risk loci for coronary artery disease

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Article: PLOS ONE. 2013;8(12):e83122

Association of TERC and OBFC1 Haplotypes with Mean Leukocyte Telomere Length and Risk for Coronary Heart Disease

Maubaret CG; Salpea KD; Romanoski CE; Folkersen L; Cooper JA; Stephanou C; Li KW; Palmen J; Hamsten A; Neil A; Stephens JW; Lusis AJ; Eriksson P; Talmud PJ; Humphries SE
Article: PLOS ONE. 2013;8(11):e79473

Genetic Variation in SULF2 Is Associated with Postprandial Clearance of Triglyceride-Rich Remnant Particles and Triglyceride Levels in Healthy Subjects

Matikainen N; Burza MA; Romeo S; Hakkarainen A; Adiels M; Folkersen L; Eriksson P; Lundbom N; Ehrenborg E; Orho-Melander M; Taskinen M-R; Boren J
Article: JOURNAL OF MOLECULAR MEDICINE-JMM. 2013;91(1):129-139

Identification of a novel flow-mediated gene expression signature in patients with bicuspid aortic valve

Maleki S; Bjorck HM; Folkersen L; Nilsson R; Renner J; Caidahl K; Franco-Cereceda A; Lanne T; Eriksson P
Article: BLOOD. 2012;120(24):4873-4881

Genome-wide association study for circulating levels of PAI-1 provides novel insights into its regulation

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Article: CIRCULATION-GENOMIC AND PRECISION MEDICINE. 2012;5(6):656-665

Identification of the BCAR1-CFDP1-TMEM170A Locus as a Determinant of Carotid Intima-Media Thickness and Coronary Artery Disease Risk

Gertow K; Sennblad B; Strawbridge RJ; Oehrvik J; Zabaneh D; Shah S; Veglia F; Fava C; Kavousi M; McLachlan S; Kivimaeki M; Bolton JL; Folkersen L; Gigante B; Leander K; Vikstrom M; Larsson M; Silveira A; Deanfield J; Voight BF; Fontanillas P; Sabater-Lleal M; Colombo GI; Kumari M; Langenberg C; Wareham NJ; Uitterlinden AG; Gabrielsen A; Hedin U; Franco-Cereceda A; Nyyssonen K; Rauramaa R; Tuomainen T-P; Savonen K; Smit AJ; Giral P; Mannarino E; Robertson CM; Talmud PJ; Hedblad B; Hofman A; Erdmann J; Reilly MP; O'Donnell CJ; Farrall M; Clarke R; Franzosi MG; Seedorf U; Syvanen A-C; Hansson GK; Eriksson P; Samani NJ; Watkins H; Price JF; Hingorani AD; Melander O; Witteman JCM; Baldassarre D; Tremoli E; de Faire U; Humphries SE; Hamsten A
Article: CIRCULATION-GENOMIC AND PRECISION MEDICINE. 2012;5(6):630-638

Integration of Genetics into a Systems Model of Electrocardiographic Traits Using HumanCVD BeadChip

Gaunt TR; Shah S; Nelson CP; Drenos F; Braund PS; Adeniran I; Folkersen L; Lawlor DA; Casas J-P; Amuzu A; Kivimaki M; Whittaker J; Eriksson P; Zhang H; Hancox JC; Tomaszewski M; Burton PR; Tobin MD; Humphries SE; Talmud PJ; Macfarlane PW; Hingorani AD; Samani NJ; Kumari M; Day INM
Article: CLINICAL PHYSIOLOGY AND FUNCTIONAL IMAGING. 2012;32(6):470-475

Real-time imaging required for optimal echocardiographic assessment of aortic valve calcification

Yousry M; Rickenlund A; Petrini J; Gustavsson T; Prahl U; Liska J; Eriksson P; Franco-Cereceda A; Eriksson MJ; Caidahl K
Article: LIPIDS IN HEALTH AND DISEASE. 2012;11:115

Expression of ceramide-metabolising enzymes in subcutaneous and intra-abdominal human adipose tissue

Kolak M; Gertow J; Westerbacka J; Summers SA; Liska J; Franco-Cereceda A; Oresic M; Yki-Jarvinen H; Eriksson P; Fisher RM
Article: THROMBOSIS AND HAEMOSTASIS. 2012;108(3):485-492

Stimulated in vivo synthesis of plasminogen activator inhibitor-1 in human adipose tissue

Ekstrom M; Liska J; Eriksson P; Sverremark-Ekstrom E; Tornvall P
Article: JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY. 2012;144(2):459-466

Matrix metalloproteinase 14 and 19 expression is associated with thoracic aortic aneurysms

Jackson V; Olsson T; Kurtovic S; Folkersen L; Paloschi V; Wagsater D; Franco-Cereceda A; Eriksson P
Article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2012;32(8):2008-2016

A Genome-Wide Association Study Identifies KNG1 as a Genetic Determinant of Plasma Factor XI Level and Activated Partial Thromboplastin Time

Sabater-Lleal M; Martinez-Perez A; Buil A; Folkersen L; Carlos Souto J; Bruzelius M; Borrell M; Odeberg J; Silveira A; Eriksson P; Almasy L; Hamsten A; Manuel Soria J
Article: DIABETES. 2012;61(8):2176-2186

Impact of Common Variation in Bone-Related Genes on Type 2 Diabetes and Related Traits

Billings LK; Hsu Y-H; Ackerman RJ; Dupuis J; Voight BF; Rasmussen-Torvik LJ; Hercberg S; Lathrop M; Barnes D; Langenberg C; Hui J; Fu M; Bouatia-Naji N; Lecoeur C; An P; Magnusson PK; Surakkaza I; Ripatti S; Christiansen L; Dalgard C; Folkersen L; Grundberg E; Eriksson P; Kaprio J; Kyvik KO; Pedersen NL; Borecki IB; Province MA; Balkau B; Froguel P; Shuldiner AR; Palmer LJ; Wareham N; Meneton P; Johnson T; Pankow JS; Karasik D; Meigs JB; Kiel DP; Florez JC
Article: INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE. 2012;30(2):288-294

Serine protease inhibitor A3 in atherosclerosis and aneurysm disease

Wagsater D; Johansson D; Fontaine V; Vorkapic E; Backlund A; Razuvaev A; Mayranpaa MI; Hjerpe C; Caidahl K; Hamsten A; Franco-Cereceda A; Wilbertz J; Swedenborg J; Zhou X; Eriksson P
Article: GENDER MEDICINE. 2012;9(4):259-266.e2

Biomarkers for Abdominal Aortic Aneurysms From a Sex Perspective

Villard C; Wagsater D; Swedenborg J; Eriksson P; Hultgren R
Article: AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY. 2012;303(1):H57-H65

Increases in intracellular sodium activate transcription and gene expression via the salt-inducible kinase 1 network in an atrial myocyte cell line

Popov S; Venetsanou K; Chedrese PJ; Pinto V; Takemori H; Franco-Cereceda A; Eriksson P; Mochizuki N; Soares-da-Silva P; Bertorello AM
Article: ATHEROSCLEROSIS. 2012;223(1):223-229

Serum 25-hydroxyvitamin D concentration, established and emerging cardiovascular risk factors and risk of myocardial infarction before the age of 60 years

Deleskog A; Piksasova O; Silveira A; Samnegard A; Tornvall P; Eriksson P; Gustafsson S; Ostenson C-G; Ohrvik J; Hamsten A
Article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2012;32(6):1526-1534

Common and Low-Frequency Genetic Variants in the PCSK9 Locus Influence Circulating PCSK9 Levels

Chernogubova E; Strawbridge R; Mahdessian H; Malarstig A; Krapivner S; Gigante B; Hellenius M-L; de Faire U; Franco-Cereceda A; Syvaenen A-C; Troutt JS; Konrad RJ; Eriksson P; Hamsten A; van 't Hooft FM
Article: MOLECULAR MEDICINE. 2012;18(4):712-718

A CYP26B1 Polymorphism Enhances Retinoic Acid Catabolism and May Aggravate Atherosclerosis

Krivospitskaya O; Elmabsout AA; Sundman E; Soderstrom LA; Ovchinnikova O; Gidlof AC; Scherbak N; Norata GD; Samnegard A; Torma H; Abdel-Halim SM; Jansson J-H; Eriksson P; Sirsjo A; Olofsson PS
Article: PLOS ONE. 2012;7(2):e32306

Combined Chromatin and Expression Analysis Reveals Specific Regulatory Mechanisms within Cytokine Genes in the Macrophage Early Immune Response

Iglesias MJ; Reilly S-J; Emanuelsson O; Sennblad B; Najafabadi MP; Folkersen L; Malarstig A; Lagergren J; Eriksson P; Hamsten A; Odeberg J
Article: PLOS ONE. 2012;7(12):e52227

Characterization of Shear-Sensitive Genes in the Normal Rat Aorta Identifies Hand2 as a Major Flow-Responsive Transcription Factor

Bjorck HM; Renner J; Maleki S; Nilsson SFE; Kihlberg J; Folkersen L; Karlsson M; Ebbers T; Eriksson P; Lanne T
Article: PLOS GENETICS. 2012;8(8):e1002908

Use of Allele-Specific FAIRE to Determine Functional Regulatory Polymorphism Using Large-Scale Genotyping Arrays

Smith AJP; Howard P; Shah S; Eriksson P; Stender S; Giambartolomei C; Folkersen L; Tybjaerg-Hansen A; Kumari M; Palmen J; Hingorani AD; Talmud PJ; Humphries SE
Article: PLOS ONE. 2012;7(7):e41139

Functional Analysis of Two PLA2G2A Variants Associated with Secretory Phospholipase A2-IIA Levels

Exeter HJ; Folkersen L; Palmen J; Franco-Cereceda A; Cooper JA; Kalea AZ; van't Hooft F; Eriksson P; Humphries SE; Talmud PJ
Article: PLOS ONE. 2012;7(6):e39574

The Chromosome 9p21.3 Coronary Heart Disease Risk Allele Is Associated with Altered Gene Expression in Normal Heart and Vascular Tissues

Pilbrow AP; Folkersen L; Pearson JF; Brown CM; McNoe L; Wang NM; Sweet WE; Tang WHW; Black MA; Troughton RW; Richards AM; Franco-Cereceda A; Gabrielsen A; Eriksson P; Moravec CS; Cameron VA
Article: AMERICAN JOURNAL OF HUMAN GENETICS. 2011;89(5):619-627

Abdominal Aortic Aneurysm Is Associated with a Variant in Low-Density Lipoprotein Receptor-Related Protein 1

Bown MJ; Jones GT; Harrison SC; Wright BJ; Bumpstead S; Baas AF; Gretarsdottir S; Badger SA; Bradley DT; Burnand K; Child AH; Clough RE; Cockerill G; Hafez H; Scott DJA; Futers S; Johnson A; Sohrabi S; Smith A; Thompson MM; van Bockxmeer FM; Waltham M; Matthiasson SE; Thorleifsson G; Thorsteinsdottir U; Blankensteijn JD; Teijink JAW; Wijmenga C; de Graaf J; Kiemeney LA; Assimes TL; McPherson R; Folkersen L; Franco-Cereceda A; Palmen J; Smith AJ; Sylvius N; Wild JB; Refstrup M; Edkins S; Gwilliam R; Hunt SE; Potter S; Lindholt JS; Frikke-Schmidt R; Tybjaerg-Hansen A; Hughes AE; Golledge J; Norman PE; van Rij A; Powel JT; Eriksson P; Stefansson K; Thompson JR; Humphries SE; Sayers RD; Deloukas P; Samani NJ
Article: DIABETES. 2011;60(10):2624-2634

Genome-Wide Association Identifies Nine Common Variants Associated With Fasting Proinsulin Levels and Provides New Insights Into the Pathophysiology of Type 2 Diabetes

Strawbridge RJ; Dupuis J; Prokopenko I; Barker A; Ahlqvist E; Rybin D; Petrie JR; Travers ME; Bouatia-Naji N; Dimas AS; Nica A; Wheeler E; Chen H; Voight BF; Taneera J; Kanoni S; Peden JF; Turrini F; Gustafsson S; Zabena C; Almgren P; Barker DJP; Barnes D; Dennison EM; Eriksson JG; Eriksson P; Eury E; Folkersen L; Fox CS; Frayling TM; Goel A; Gu HF; Horikoshi M; Isomaa B; Jackson AU; Jameson KA; Kajantie E; Kerr-Conte J; Kuulasmaa T; Kuusisto J; Loos RJF; Luan J; Makrilakis K; Manning AK; Teresa Martinez-Larrad M; Narisu N; Mannila MN; Ohrvik J; Osmond C; Pascoe L; Payne F; Sayer AA; Sennblad B; Silveira A; Stancakova A; Stirrups K; Swift AJ; Syvanen A-C; Tuomi T; van 't Hooft FM; Walker M; Weedon MN; Xie W; Zethelius B; Ongen H; Malarstig A; Hopewell JC; Saleheen D; Chambers J; Parish S; Danesh J; Kooner J; Ostenson C-G; Lind L; Cooper CC; Serrano-Rios M; Ferrannini E; Forsen TJ; Clarke R; Franzosi MG; Seedorf U; Watkins H; Froguel P; Johnson P; Deloukas P; Collins FS; Laakso M; Dermitzakis ET; Boehnke M; McCarthy MI; Wareham NJ; Groop L; Pattou F; Gloyn AL; Dedoussis GV; Lyssenko V; Meigs JB; Barroso I; Watanabe RM; Ingelsson E; Langenberg C; Hamsten A; Florez JC
Article: ANNALS OF THORACIC SURGERY. 2011;92(4):1376-1382

Mortality in Acute Type A Aortic Dissection: Validation of the Penn Classification

Olsson C; Hillebrant C-G; Liska J; Lockowandt U; Eriksson P; Franco-Cereceda A
Article: ATHEROSCLEROSIS. 2011;218(2):294-299

Protease activity in the multi-layered intra-luminal thrombus of abdominal aortic aneurysms

Folkesson M; Silveira A; Eriksson P; Swedenborg J
Article: JOURNAL OF INTERNAL MEDICINE. 2011;270(3):229-236

Plasma CD93 concentration is a potential novel biomarker for coronary artery disease

Malarstig A; Silveira A; Wagsater D; Ohrvik J; Backlund A; Samnegard A; Khademi M; Hellenius M-L; Leander K; Olsson T; Uhlen M; de Faire U; Eriksson P; Hamsten A
Article: EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY. 2011;40(3):e118-e124

Bicuspid aortic valve leaflet morphology in relation to aortic root morphology: a study of 300 patients undergoing open-heart surgery

Jackson V; Petrini J; Caidahl K; Eriksson MJ; Liska J; Eriksson P; Franco-Cereceda A
Article: JOURNAL OF VASCULAR SURGERY. 2011;54(2):341-345.e2

Reproductive history in women with abdominal aortic aneurysms

Villard C; Swedenborg J; Eriksson P; Hultgren R
Article: INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE. 2011;28(2):247-253

MMP-2 and MMP-9 are prominent matrix metalloproteinases during atherosclerosis development in the LdlrApob100/100 moused

Wagsater D; Zhu C; Bjorkegren J; Skogsberg J; Eriksson P
Article: INFLAMMATION. 2011;34(4):225-230

Effects of Simvastatin on Proinflammatory Cytokines and Matrix Metalloproteinases in Hypercholesterolemic Individuals

Nilsson L; Eriksson P; Cherfan P; Jonasson L
Article: AMERICAN JOURNAL OF HYPERTENSION. 2011;24(7):802-808

Gender-Specific Association of the Plasminogen Activator Inhibitor-1 4G/5G Polymorphism With Central Arterial Blood Pressure

Bjorck HM; Eriksson P; Alehagen U; De Basso R; Ljungberg LU; Persson K; Dahlstrom U; Lanne T
Article: DIABETES. 2011;60(7):1894-1900

Comparison of Dorsocervical With Abdominal Subcutaneous Adipose Tissue in Patients With and Without Antiretroviral Therapy-Associated Lipodystrophy

Sevastianova K; Sutinen J; Greco D; Sievers M; Salmenkivi K; Perttila J; Olkkonen VM; Wagsater D; Lidell ME; Enerback S; Eriksson P; Walker UA; Auvinen P; Ristola M; Yki-Jarvinen H
Article: CIRCULATION. 2011;123(12):1316-1325

Upregulation of the 5-Lipoxygenase Pathway in Human Aortic Valves Correlates With Severity of Stenosis and Leads to Leukotriene-Induced Effects on Valvular Myofibroblasts

Nagy E; Andersson DC; Caidahl K; Eriksson MJ; Eriksson P; Franco-Cereceda A; Hansson GK; Back M
Article: PLOS ONE. 2011;6(3):e17652

A Common Polymorphism in the Promoter Region of the TNFSF4 Gene Is Associated with Lower Allele-Specific Expression and Risk of Myocardial Infarction

Ria M; Lagercrantz J; Samnegard A; Boquist S; Hamsten A; Eriksson P
Article: NATURE GENETICS. 2011;43(4):339-U89

A genome-wide association study in Europeans and South Asians identifies five new loci for coronary artery disease

Peden JF; Hopewell JC; Saleheen D; Chambers JC; Hager J; Soranzo N; Collins R; Danesh J; Elliott P; Farrall M; Stirrups K; Zhang W; Hamsten A; Parish S; Lathrop M; Watkins H; Clarke R; Deloukas P; Kooner JS; Goel A; Ongen H; Strawbridge RJ; Heath S; Malarstig A; Helgadottir A; Ohrvik J; Murtaza M; Potter S; Hunt SE; Delepine M; Jalilzadeh S; Axelsson T; Syvanen A-C; Gwilliam R; Bumpstead S; Gray E; Edkins S; Folkersen L; Kyriakou T; Franco-Cereceda A; Gabrielsen A; Seedorf U; Eriksson P; Offer A; Bowman L; Sleight P; Armitage J; Peto R; Abecasis G; Ahmed N; Caulfield M; Donnelly P; Froguel P; Kooner AS; McCarthy MI; Samani NJ; Scott J; Sehmi J; Silveira A; Hellenius M-L; van't Hooft FM; Olsson G; Rust S; Assmann G; Barlera S; Tognoni G; Franzosi MG; Linksted P; Green FR; Rasheed A; Zaidi M; Shah N; Samuel M; Mallick NH; Azhar M; Zaman KS; Samad A; Ishaq M; Gardezi AR; Memon F-U; Frossard PM; Spector T; Peltonen L; Nieminen MS; Sinisalo J; Salomaa V; Ripatti S; Bennett D; Leander K; Gigante B; de Faire U; Pietri S; Gori F; Marchioli R; Sivapalaratnam S; Kastelein JJP; Trip MD; Theodoraki EV; Dedoussis GV; Engert JC; Yusuf S; Anand SS
Article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2011;31(3):691-697

Impaired Splicing of Fibronectin Is Associated With Thoracic Aortic Aneurysm Formation in Patients With Bicuspid Aortic Valve

Paloschi V; Kurtovic S; Folkersen L; Gomez D; Wagsaeter D; Roy J; Petrini J; Eriksson MJ; Caidahl K; Hamsten A; Liska J; Michel J-B; Franco-Cereceda A; Eriksson P
Article: MOLECULAR MEDICINE. 2011;17(7-8):665-675

Diverging Alternative Splicing Fingerprints in the Transforming Growth Factor-β Signaling Pathway Identified Thoracic Aortic Aneurysms

Kurtovic S; Paloschi V; Folkersen L; Gottfries J; Franco-Cereceda A; Eriksson P
Article: MOLECULAR MEDICINE. 2011;17(11-12):1365-1373

Unraveling Divergent Gene Expression Profiles in Bicuspid and Tricuspid Aortic Valve Patients with Thoracic Aortic Dilatation: The ASAP Study

Folkersen L; Wagsater D; Paloschi V; Jackson V; Petrini J; Kurtovic S; Maleki S; Eriksson MJ; Caidahl K; Hamsten A; Michel J-B; Liska J; Gabrielsen A; Franco-Cereceda A; Eriksson P
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2010;107(49):21093-21097

Increased expression of leukotriene C₄ synthase and predominant formation of cysteinyl-leukotrienes in human abdominal aortic aneurysm

Di Gennaro A; Wagsater D; Mayranpaa MI; Gabrielsen A; Swedenborg J; Hamsten A; Samuelsson B; Eriksson P; Haeggstrom JZ
Article: JOURNAL OF HEART VALVE DISEASE. 2010;19(6):724-730

Endothelin-1 and Brain Natriuretic Peptide Plasma Levels Decrease After Aortic Surgery

Raffa GM; Jackson V; Liska J; Eriksson MJ; Caidahl K; Eriksson P; Franco-Cereceda A
Article: THROMBOSIS AND HAEMOSTASIS. 2010;104(5):998-1008

Allele-specific transcription of the PAI-1 gene in human astrocytes

Hultman K; Wolf AT; Odeberg J; Eriksson P; Jern C
Article: JOURNAL OF THE AMERICAN SOCIETY OF ECHOCARDIOGRAPHY. 2010;23(9):985-992

The Feasibility of Velocity Vector Imaging by Transesophageal Echocardiography for Assessment of Elastic Properties of the Descending Aorta in Aortic Valve Disease

Petrini J; Yousry M; Rickenlund A; Liska J; Hamsten A; Eriksson P; Franco-Cereceda A; Caidahl K; Eriksson MJ
Article: METABOLISM-CLINICAL AND EXPERIMENTAL. 2010;59(9):1316-1318

Preliminary report: Zn-alpha2-glycoprotein genotype and serum levels are associated with serum lipids

Olofsson LE; Olsson B; Lystig T; Jacobson P; Jernas M; Sjoholm K; Gummesson A; Sjostrom L; Eriksson P; Hamsten A; Hale LP; Thelle DS; Carlsson B; Carlsson LMS
Article: NATURE GENETICS. 2010;42(8):692-697

Genome-wide association study identifies a sequence variant within the DAB2IP gene conferring susceptibility to abdominal aortic aneurysm

Gretarsdottir S; Baas AF; Thorleifsson G; Holm H; den Heijer M; de Vries J-PPM; Kranendonk SE; Zeebregts CJAM; van Sterkenburg SM; Geelkerken RH; van Rij AM; Williams MJA; Boll APM; Kostic JP; Jonasdottir A; Jonasdottir A; Walters GB; Masson G; Sulem P; Saemundsdottir J; Mouy M; Magnusson KP; Tromp G; Elmore JR; Sakalihasan N; Limet R; Defraigne J-O; Ferrell RE; Ronkainen A; Ruigrok YM; Wijmenga C; Grobbee DE; Shah SH; Granger CB; Quyyumi AA; Vaccarino V; Patel RS; Zafari AM; Levey AI; Austin H; Girelli D; Pignatti PF; Olivieri O; Martinelli N; Malerba G; Trabetti E; Becker LC; Becker DM; Reilly MP; Rader DJ; Mueller T; Dieplinger B; Haltmayer M; Urbonavicius S; Lindblad B; Gottsater A; Gaetani E; Pola R; Wells P; Rodger M; Forgie M; Langlois N; Corral J; Vicente V; Fontcuberta J; Espana F; Grarup N; Jorgensen T; Witte DR; Hansen T; Pedersen O; Aben KK; de Graaf J; Holewijn S; Folkersen L; Franco-Cereceda A; Eriksson P; Collier DA; Stefansson H; Steinthorsdottir V; Rafnar T; Valdimarsson EM; Magnadottir HB; Sveinbjornsdottir S; Olafsson I; Magnusson MK; Palmason R; Haraldsdottir V; Andersen K; Onundarson PT; Thorgeirsson G; Kiemeney LA; Powell JT; Carey DJ; Kuivaniemi H; Lindholt JS; Jones GT; Kong A; Blankensteijn JD; Matthiasson SE; Thorsteinsdottir U; Stefansson K
Article: CIRCULATION-GENOMIC AND PRECISION MEDICINE. 2010;3(4):365-373

Association of Genetic Risk Variants With Expression of Proximal Genes Identifies Novel Susceptibility Genes for Cardiovascular Disease

Folkersen L; van't Hooft F; Chernogubova E; Agardh HE; Hansson GK; Hedin U; Liska J; Syvanen A-C; Paulssson-Berne G; Franco-Cereceda A; Hamsten A; Gabrielsen A; Eriksson P
Article: JOURNAL OF INTERNAL MEDICINE. 2010;268(2):194-205

Low plasma adiponectin concentration is associated with myocardial infarction in young individuals

Persson J; Lindberg K; Gustafsson TP; Eriksson P; Paulsson-Berne G; Lundman P
Article: AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM. 2010;299(2):E234-E240

Systemic inflammation activates the nuclear factor-κB regulatory pathway in adipose tissue

Ekstrom M; Halle M; Bjessmo S; Liska J; Kolak M; Fisher R; Eriksson P; Tornvall P
Article: JOURNAL OF LIPID RESEARCH. 2010;51(1):103-111

Allele-specific regulation of MTTP expression influences the risk of ischemic heart disease

Aminoff A; Ledmyr H; Thulin P; Lundell K; Nunez L; Strandhagen E; Murphy C; Lidberg U; Westerbacka J; Franco-Cereceda A; Liska J; Nielsen LB; Gafvels M; Mannila MN; Hamsten A; Yki-Jarvinen H; Thelle D; Eriksson P; Boren J; Ehrenborg E
Journal article: ARTERY RESEARCH. 2009;3(4):177-178

P2.03 The Plasminogen Activator Inhibitor-1 (4G/5G) Polymorphism Affects Central Arterial Blood Pressure in Women

Björck HM; Eriksson P; Alehagen U; Ljungberg LU; DeBasso R; Persson K; Dahlström U; Länne T
Article: PLOS ONE. 2009;4(11):e7677

Relationship between CAD Risk Genotype in the Chromosome 9p21 Locus and Gene Expression. Identification of Eight New ANRIL Splice Variants

Folkersen L; Kyriakou T; Goel A; Peden J; Malarstig A; Paulsson-Berne G; Hamsten A; Franco-Cereceda A; Gabrielsen A; Eriksson P; Watkins H
Article: CIRCULATION JOURNAL. 2009;73(8):1531-1536

A Functional Interleukin-1 Receptor Antagonist Polymorphism Influences Atherosclerosis Development - The Interleukin-1β:Interleukin-1 Receptor Antagonist Balance in Atherosclerosis -

Olofsson PS; Sheikine Y; Jatta K; Ghaderi M; Samnegard A; Eriksson P; Sirsjoe A
Article: JOURNAL OF VASCULAR SURGERY. 2009;50(2):388-395

Mast cells associate with neovessels in the media and adventitia of abdominal aortic aneurysms

Mayranpaa MI; Trosien JA; Fontaine V; Folkesson M; Kazi M; Eriksson P; Swedenborg J; Hedin U
Article: BIOINFORMATICS. 2009;25(15):1978-1979

GeneRegionScan: a Bioconductor package for probe-level analysis of specific, small regions of the genome

Folkersen L; Diez D; Wheelock CE; Haeggstrom JZ; Goto S; Eriksson P; Gabrielsen A
Article: JOURNAL OF INFECTIOUS DISEASES. 2009;200(2):252-262

Gene Expression and Immunohistochemistry in Adipose Tissue of HIV Type 1-Infected Patients with Nucleoside Analogue Reverse-Transcriptase Inhibitor-Associated Lipoatrophy

Sievers M; Walker UA; Sevastianova K; Setzer B; Wagsater D; Eriksson P; Yki-Jarvinen H; Sutinen J
Journal article: ATHEROSCLEROSIS PLUS. 2009;10(2):e417

Abstract: 1068 LOW ADIPONECTIN CONCENTRATION IS A RISK FACTOR FOR MYOCARDIAL INFARCTION AND LEVELS ARE INFLUENCED BY GENETIC VARIANTS

Persson J; Eriksson P; Gustafsson T; Berne GP; Lundman P
Article: JOURNAL OF MOLECULAR MEDICINE-JMM. 2009;87(4):337-346

Genetic variants of TNFSF4 and risk for carotid artery disease and stroke

Olofsson PS; Soderstrom LA; Jern C; Sirsjoe A; Ria M; Sundler E; de Faire U; Wiklund PG; Ohrvik J; Hedin U; Paulsson-Berne G; Hamsten A; Eriksson P; Hansson GK
Article: JOURNAL OF INTERNAL MEDICINE. 2009;265(3):373-381

Association of genetic variation on chromosome 9p21.3 and arterial stiffness

Bjorck HM; Lanne T; Alehagen U; Persson K; Rundkvist L; Hamsten A; Dahlstrom U; Eriksson P
Article: ATHEROSCLEROSIS. 2009;202(2):550-556

Gender specific associations between matrix metalloproteinases and inflammatory markers in post myocardial infarction patients

Samnegarda A; Hulthe J; Silveira A; Ericsson C-G; Hamsten A; Eriksson P
Article: ATHEROSCLEROSIS. 2009;202(2):415-423

Effects of PDGF-C and PDGF-D on monocyte migration and MMP-2 and MMP-9 expression

Wagsaeter D; Zhu C; Bjoerck HM; Eriksson P
Article: AMERICAN JOURNAL OF PATHOLOGY. 2009;174(2):693-700

T-Cell Activation Leads to Reduced Collagen Maturation in Atherosclerotic Plaques of Apoe^-/- Mice

Ovchinnikova O; Robertson A-KL; Wagsater D; Folco EJ; Hyry M; Myllyharju J; Eriksson P; Libby P; Hansson GK
Article: JOURNAL OF VIROLOGY. 2009;83(2):830-835

Infection with Human Cytomegalovirus Alters the MMP-9/TIMP-1 Balance in Human Macrophages

Straat K; de Klark R; Gredmark-Russ S; Eriksson P; Soderberg-Naucler C
Article: SCANDINAVIAN CARDIOVASCULAR JOURNAL. 2008;42(5):327-336

Surgical handling of saphenous vein grafts induces expression of matrix metalloproteinase 9

Chen F; Eriksson P; Whatling C; Vaage J; Valen G
Journal article: ARTERY RESEARCH. 2008;2(3):115-116

P2.38 The Anril Locus on Chromosome 9P21 Affects Stiffness of the Abdominal Aorta

Bjorck HM; Lanne T; Alehagen U; Persson K; Rundkvist L; Hamsten A; Dahlstrom U; Eriksson P
Article: HEART. 2008;94(6):724-729

Raised interleukin-10 is an indicator of poor outcome and enhanced systemic inflammation in patients with acute coronary syndrome

Malarstig A; Eriksson P; Hamsten A; Lindahl B; Wallentin L; Siegbahn A
Article: INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE. 2008;21(6):697-704

Expression profiling of macrophages from subjects with atherosclerosis to identify novel susceptibility genes

Hagg DA; Jernas M; Wiklund O; Thelle DS; Fagerberg B; Eriksson P; Hamsten A; Olsson B; Carlsson B; Carlsson LMS; Svensson P-A
Article: JOURNAL OF INTERNAL MEDICINE. 2008;263(5):538-552

Identifying the susceptibility genes for coronary artery disease: from hyperbole through doubt to cautious optimism

Hamsten A; Eriksson P
Article: CLINICAL CHEMISTRY. 2008;54(5):833-840

Genetic variants of tumor necrosis factor superfamily, member 4 (TNFSF4), and risk of incident atherothrombosis and venous thromboembolism

Maelarstig A; Eriksson P; Rose L; Diehl KA; Hamsten A; Ridker PM; Zee RYL
Article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2008;28(5):975-982

Variants of the interferon regulatory factor 5 gene regulate expression of IRF5 mRNA in atherosclerotic tissue but are not associated with myocardial infarction

Malarstig A; Sigurdsson S; Eriksson P; Paulsson-Berne G; Hedin U; Wallentin L; Siegbahn A; Hamsten A; Syvanen A-C
Article: HUMAN MOLECULAR GENETICS. 2008;17(6):806-814

Susceptibility to coronary artery disease and diabetes is encoded by distinct, tightly linked SNPs in the ANRIL locus on chromosome 9p

Broadbent HM; Peden JF; Lorkowski S; Goel A; Ongen H; Green F; Clarke R; Collins R; Franzosi MG; Tognoni G; Seedorf U; Rust S; Eriksson P; Hamsten A; Farrall M; Watkins H
Article: ATHEROSCLEROSIS. 2008;196(2):514-522

ADAMTS-4 and-8 are inflammatory regulated enzymes expressed in macrophage-rich areas of human atherosclerotic plaques

Wagsater D; Bjork H; Zhu C; Bjorkegren J; Valen G; Hamsten A; Eriksson P
Article: CLINICAL AND EXPERIMENTAL IMMUNOLOGY. 2008;151(2):317-325

Human T cells stimulate fibroblast-mediated degradation of extracellular matrix in vitro

Mikko M; Fredriksson K; Wahlstrom J; Eriksson P; Grunewald J; Skold CM
Article: PLOS COMPUTATIONAL BIOLOGY. 2008;4(1):e5

In silico detection of sequence variations modifying transcriptional regulation

Andersen MC; Engstrom PRG; Lithwick S; Arenillas D; Eriksson P; Lenhard B; Wasserman WW; Odeberg J
Article: TRANSLATIONAL RESEARCH. 2007;150(5):303-310

Effects of neurotrophins on human bronchial smooth muscle cell migration and matrix metalloproteinase-9 secretion

Dagnell C; Kemi C; Klominek J; Eriksson P; Skoeld CM; Eklund A; Grunewald J; Hoeglund CO
Article: THROMBOSIS AND HAEMOSTASIS. 2007;98(2):427-433

Presence of NGAL/MMP-9 complexes in human abdominal aortic aneurysms

Folkesson M; Kazi M; Zh C; Silveira A; Hemclahl A-L; Harristen A; Hedin U; Swedenborg J; Eriksson P
Article: DIABETES. 2007;56(8):1960-1968

Adipose tissue inflammation and increased ceramide content characterize subjects with high liver fat content independent of obesity

Kolak M; Westerbacka J; Velagapudi VR; Wagsater D; Yetukuri L; Makkonen J; Rissanen A; Hakkinen A-M; Lindell M; Bergholm R; Hamsten A; Eriksson P; Fisher RM; Oresic M; Yki-Jarvinen H
Article: ATHEROSCLEROSIS. 2007;193(2):321-327

Post-prandial endothelial dysfunction in hypertriglyceridemic subjects: Molecular mechanisms and gene expression studies

Norata GD; Grigore L; Raselli S; Redaelli L; Hamsten A; Maggi F; Eriksson P; Catapano AL
Article: BLOOD COAGULATION & FIBRINOLYSIS. 2007;18(5):473-477

Coagulation factor VII and inflammatory markers in patients with coronary heart disease

Ekstrom M; Silveira A; Bennermo M; Eriksson P; Tornvall P
Article: JOURNAL OF APPLIED PHYSIOLOGY. 2007;102(6):2346-2351

A single bout of exercise activates matrix metalloproteinase in human skeletal muscle

Rullman E; Rundqvist H; Wagsater D; Fischer H; Eriksson P; Sundberg CJ; Jansson E; Gustafsson T
Article: JOURNAL OF THROMBOSIS AND HAEMOSTASIS. 2007;5(4):766-773

Elevated plasma fibrinogen γ′ concentration is associated with myocardial infarction:: effects of variation in fibrinogen genes and environmental factors

Mannila MN; Lovely RS; Kazmierczak SC; Eriksson P; Samnegard A; Farrell DH; Hamsten A; Silveira A
Article: JOURNAL OF INTERNAL MEDICINE. 2007;261(2):138-147

The association between fibrinogen haplotypes and myocardial infarction in men is partly mediated through pleiotropic effects on the serum IL-6 concentration

Mannila MN; Eriksson P; Leander K; Wiman B; de Faire U; Hamsten A; Silveira A
Article: JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM. 2007;92(2):720-724

Effects of chronic rosiglitazone therapy on gene expression in human adipose tissue in vivo in patients with type 2 diabetes

Kolak M; Yki-Jarvinen H; Kannisto K; Tiikkainen M; Hamsten A; Eriksson P; Fisher RM
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2006;351(3):777-783

Allele-specific chromatin remodeling of the tumor necrosis factor-α promoter

Skoog T; Hamsten A; Eriksson P
Article: EUROPEAN JOURNAL OF CLINICAL NUTRITION. 2006;60(12):1406-1413

Fatty acid handling protein expression in adipose tissue, fatty acid composition of adipose tissue and serum, and markers of insulin resistance

Gertow K; Rosell M; Sjogren P; Eriksson P; Vessby B; de Faire U; Hamsten A; Hellenius M-L; Fisher RM
Article: HUMAN REPRODUCTION. 2006;21(12):3146-3156

Endometrial expression of the estrogen-sensitive genes MMP-26 and TIMP-4 is altered by a substitution protocol without down-regulation in IVF patients

Pilka R; Oborna I; Lichnovsky V; Havelka P; Fingerova H; Eriksson P; Hansson S; Casslen B
Article: AMERICAN JOURNAL OF PATHOLOGY. 2006;169(6):2245-2253

Induction of neutrophil gelatinase-associated lipocalin in vascular injury via activation of nuclear factor-κB

Bu D-X; Hemdahl A-L; Gabrielsen A; Fuxe J; Zhu C; Eriksson P; Yan Z-Q
Article: ATHEROSCLEROSIS. 2006;188(2):450-454

Plasma interleukin (IL)-18 concentrations is elevated in patients with previous myocardial infarction and related-to severity of coronary atherosclerosis independently of C-reactive protein and IL-6

Hulthe J; McPheat W; Samnegard A; Tornvall P; Hamsten A; Eriksson P
Article: ATHEROSCLEROSIS. 2006;188(2):462-466

Decreased plasma CXCL16/SR-PSOX concentration is associated with coronary artery disease

Sheikine Y; Bang CS; Nilsson L; Samnegard A; Hamsten A; Jonasson L; Eriksson P; Sirsjo A
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2006;348(3):1150-1156

Allele-specific MMP-3 transcription under in vivo conditions

Zhu C; Odeberg J; Hamsten A; Eriksson P
Journal article: VASCULAR PHARMACOLOGY. 2006;45(3):e145-e146

Presence of NGAL/MMP-9 complexes in human abdominal aortic aneurysms

Folkesson M; Kazi M; Zhu C; Swedenborg J; Eriksson P; Hedin U; Hamsten A
Article: CLINICAL CHEMISTRY. 2006;52(8):1522-1527

Increased plasma concentration of matrix metalloproteinase-7 in patients with coronary artery disease

Nilsson L; Jonasson L; Nijm J; Hamsten A; Eriksson P
Article: JOURNAL OF INTERNAL MEDICINE. 2006;259(5):530-536

Lower serum concentration of matrix metalloproteinase-3 in the acute stage of myocardial infarction

Samnegård A; Silveira A; Tornvall P; Hamsten A; Ericsson CG; Eriksson P
Article: JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY. 2006;40(4):484-494

Triglyceride-rich lipoproteins from hypertriglyceridemic subjects induce a pro-inflammatory response in the endothelium: Molecular mechanisms and gene expression studies

Norata GD; Grigore L; Raselli S; Seccomandi PM; Hamsten A; Maggi FM; Eriksson P; Catapano AL
Article: BMC MOLECULAR BIOLOGY. 2006;7:8

Alternative promoter usage of the membrane glycoprotein CD36

Andersen M; Lenhard B; Whatling C; Eriksson P; Odeberg J
Article: THROMBOSIS AND HAEMOSTASIS. 2006;95(3):420-427

Epistatic and pleiotropic effects of polymorphisms in the fibrinogen and coagulation factor XIII genes on plasma fibrinogen concentration, fibrin gel structure and risk of myocardial infarction

Mannila MN; Eriksson P; Ericsson CG; Hamsten A; Silveira A
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2006;339(3):1001-1006

Human genetic evidence that OX40 is implicated in myocardial infarction

Ria M; Eriksson P; Boquist S; Ericsson CG; Hamsten A; Lagercrantz J
Article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2006;26(1):136-142

Expression of neutrophil gelatinase-associated lipocalin in atherosclerosis and myocardial infarction

Hemdahl AL; Gabrielsen A; Zhu CY; Eriksson P; Hedin U; Kastrup J; Thorén P; Hansson GK
Article: CIRCULATION RESEARCH. 2005;97(10):1070-1076

Haplotype effect of the matrix metalloproteinase-1 gene on risk of myocardial infarction

Pearce E; Tregouet DA; Samnegård A; Morgan AR; Cox C; Hamsten A; Eriksson P; Ye S
Article: JOURNAL OF INTERNAL MEDICINE. 2005;258(5):411-419

Serum matrix metalloproteinase-3 concentration is influenced by MMP-3-1612 5A/6A promoter genotype and associated with myocardial infarction

Samnegård A; Silveira A; Lundman P; Boquist S; Odeberg J; Hulthe J; Mcpheat W; Tornvall P; Bergstrand L; Ericsson CG; Hamsten A; Eriksson P
Article: BRITISH JOURNAL OF SURGERY. 2005;92(11):1372-1376

Genotype-phenotype relationships in an investigation of the role of proteases in abdominal aortic aneurysm expansion

Eriksson P; Jormsjö-Pettersson S; Brady AR; Deguchi H; Hamsten A; Powell JT
Article: OBESITY. 2005;13(10):1645-1650

A common β₂-adrenoceptor gene haplotype protects against obesity in Swedish women

Jiao H; Dahlman I; Eriksson P; Kere J; Arner P
Article: STROKE. 2005;36(8):1661-1665

Plasminogen activator inhibitor-1 4G/5G polymorphism and risk of stroke - Replicated findings in two nested case-control studies based on independent cohorts

Wiklund PG; Nilsson L; Ardnor SN; Eriksson P; Johansson L; Stegmayr B; Hamsten A; Holmberg D; Asplund K
Article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2005;25(7):1341-1346

Difference in matrix-degrading protease expression and activity between thrombus-free and thrombus-covered wall of abdominal aortic aneurysm

Kazi M; Zhu CY; Roy J; Paulsson-Berne G; Hamsten A; Swedenborg J; Hedin U; Eriksson P
Article: CIRCULATION. 2005;111(21):2805-2811

High-density lipoproteins induce transforming growth factor-β₂ expression in endothelial cells

Norata GD; Callegari E; Marchesi M; Chiesa G; Eriksson P; Catapano AL
Article: JOURNAL OF INTERNAL MEDICINE. 2005;257(5):415-422

Severity of coronary artery stenosis is associated with a polymorphism in the CXCL16/SR-PSOX gene

Lundberg GA; Kellin A; Samnegård A; Lundman P; Tornvall P; Dimmeler S; Zeiher AM; Hamsten A; Hansson GK; Eriksson P
Article: NATURE GENETICS. 2005;37(5):486-494

MHC2TA is associated with differential MHC molecule expression and susceptibility to rheumatoid arthritis, multiple sclerosis and myocardial infarction

Swanberg M; Lidman O; Padyukov L; Eriksson P; Åkesson E; Jagodic M; Lobell A; Khademi M; Borjesson O; Lindgren CM; Lundman P; Brookes AJ; Kere J; Luthman H; Alfredsson L; Hillert J; Klareskog L; Hamsten A; Piehl F; Olsson T
Article: CORONARY ARTERY DISEASE. 2005;16(3):191-197

Apoptosis and angiogenesis are induced in the unstable coronary atherosclerotic plaque

Chen F; Eriksson P; Kimura T; Herzfeld I; Valen G
Article: REGULATORY PEPTIDES. 2005;127(1-3):45-53

Human neuropeptide Y signal peptide gain-of-function polymorphism is associated with increased body mass index:: possible mode of function

Ding B; Kull B; Liu ZR; Mottagui-Tabar S; Thonberg H; Gu HF; Brookes AJ; Grundemar L; Karlsson C; Hamsten A; Arner P; Östenson CG; Efendic S; Monné M; von Heijne G; Eriksson P; Wahlestedt C
Article: NATURE GENETICS. 2005;37(4):365-372

Positional identification of TNFSF4, encoding OX40 ligand, as a gene that influences atherosclerosis susceptibility

Wang XS; Ria M; Kelmenson PM; Eriksson P; Higgins DC; Samnegård C; Petros C; Rollins J; Bennet AM; Wiman B; de Faire U; Wennberg C; Olsson PG; Ishii N; Sugamura K; Hamsten A; Forsman-Semb K; Lagercrantz J; Paigen B
Article: THROMBOSIS AND HAEMOSTASIS. 2005;93(3):570-577

Contribution of haplotypes across the fibrinogen gene cluster to variation in risk of myocardial infarction

Mannila MN; Eriksson P; Lundman P; Samnegård A; Boquist S; Ericsson CG; Tornvall P; Hamsten A; Silveira A
Article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2005;25(2):418-423

Genotypic effect of the -565C> T polymorphism in the ABCA1 gene promoter on ABCA1 expression and severity of atherosclerosis

Kyriakou T; Hodgkinson C; Pontefract DE; Iyengar S; Howell WM; Wong YK; Eriksson P; Ye S
Article: CESKA GYNEKOLOGIE. 2005;70(1):56-62

[MMP-26 mRNA and estrogen receptor alpha co-expression in normal and pathological endometrium].

Pilka R; Kudela M; Eriksson P; Casslén B
Journal article: PLOS COMPUTATIONAL BIOLOGY. 2005;preprint(2007):e5

In silico detection of sequence variations modifying transcriptional regulation

Andersen MC; Engström PG; Lithwick S; Arenillas D; Eriksson P; Lenhard B; Wasserman WW; Odeberg J
Article: INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE. 2005;15(1):57-65

Expression of matrix metalloproteinase 9 and its regulators in the unstable coronary atherosclerotic plaque

Chen F; Eriksson P; Hansson GK; Herzfeld I; Klein M; Hansson LO; Valen G
Article: THROMBOSIS AND HAEMOSTASIS. 2004;92(6):1240-1249

Plasma fibrinogen concentration predicts the risk of myocardial infarction differently in various parts of Europe:: Effects of β-fibrinogen genotype and environmental factors -: The HIFMECH Study

Mannila MN; Silveira A; Hawe E; Eriksson P; Aillaud MF; Juhan-Vague I; Yudkin J; Margaglione M; di Minno G; Mussoni L; Tremoli E; Humphries S; Hamsten A
Article: ATHEROSCLEROSIS. 2004;177(2):443-450

Locating Ath8, a locus for murine atherosclerosis susceptibility and testing several of its candidate genes in mice and humans

Korstanje R; Eriksson P; Samnegård A; Olsson PG; Forsman-Semb K; Sen S; Churchill GA; Rollins J; Harris S; Hamsten A; Paigen B
Article: CESKA GYNEKOLOGIE. 2004;69(6):472-476

[Endometrial expression profiles of mRNA for selected matrix metalloproteinases and tissue inhibitor of metalloproteinases-1].

Pilka R; Kudela M; Eriksson P; Casslén B
Article: DIABETOLOGIA. 2004;47(11):1974-1979

α₂-Heremans-Schmid glycoprotein gene polymorphisms are associated with adipocyte insulin action

Dahlman I; Eriksson P; Kaaman M; Jiao H; Lindgren CM; Kere J; Arner P
Article: BRITISH JOURNAL OF HAEMATOLOGY. 2004;127(1):97-104

Oxidised-HDL₃ induces the expression of PAI-1 in human endothelial cells.: Role of p38MAPK activation and mRNA stabilization

Norata GD; Banfi C; Pirillo A; Tremoli E; Hamsten A; Catapano AL; Eriksson P
Article: GYNECOLOGIC ONCOLOGY. 2004;94(3):661-670

Matrix metalloproteinase-26 (Matrilysin-2) expression is high in endometrial hyperplasia and decreases with loss of histological differentiation in endometrial cancer

Pilka R; Norata GD; Domanski H; Andersson C; Hansson S; Eriksson P; Casslén B
Article: MOLECULAR HUMAN REPRODUCTION. 2004;10(9):641-650

Endometrial TIMP-4 mRNA is high at midcycle and in hyperplasia, but down-regulated in malignant tumours.: Coordinated expression with MMP-26

Pilka R; Domanski H; Hansson S; Eriksson P; Casslén B
Article: JOURNAL OF LIPID RESEARCH. 2004;45(9):1768-1776

Effect of macrophage differentiation and exposure to mildly oxidized LDL on the proteolytic repertoire of THP-1 monocytes

Whatling C; Björk H; Gredmark S; Hamsten A; Eriksson P
Article: EUROPEAN HEART JOURNAL. 2004;25(16):1447-1453

Association of hypo-responsive toll-like receptor 4 variants with risk of myocardial infarction

Edfeldt K; Bennet AM; Eriksson P; Frostegård J; Wiman B; Hamsten A; Hansson GK; de Faire U; Yan ZQ
Article: DIABETOLOGIA. 2004;47(6):1118-1125

Expression of fatty-acid-handling proteins in human adipose tissue in relation to obesity and insulin resistance

Gertow K; Pietiläinen KH; Yki-Järvinen H; Kaprio J; Rissanen A; Eriksson P; Hamsten A; Fisher RM
Article: STROKE. 2004;35(6):1310-1315

Differences in matrix metalloproteinase-1 and matrix metalloproteinase-12 transcript levels among carotid atherosclerotic plaques with different histopathological characteristics

Morgan AR; Rerkasem K; Gallagher PJ; Zhang BP; Morris GE; Calder PC; Grimble RF; Eriksson P; McPheat WL; Shearman CP; Ye S
Journal article: CARDIOVASCULAR PATHOLOGY. 2004;13(3):29-30

HIGH-DENSITY LIPOPROTEIN SUBFRACTION 3 DECREASES ADAMTS-1 EXPRESSION INDUCED

Norata GD; Björk H; Hamsten A; Catapano AL; Eriksson P
Journal article: CARDIOVASCULAR PATHOLOGY. 2004;13(3):17-18

INFLUENCE OF INTRALUMINAL THROMBUS ON STRUCTURAL FEATURES AND GENE EXPRESSION OF THE ANEURYSM WALL

Kazi M; Roy J; Björk H; Zhu C; Hamsten A; Swedenborg J; Hedin U; Eriksson P
Journal article: CARDIOVASCULAR PATHOLOGY. 2004;13(3):96-97

INCREASED EXPRESSION OF NGAL IN ATHEROSCLEROSIS AND MYOCARDIAL INFARCTION

Hemdahl A-L; Gabrielsen A; Berne G; Eriksson P; Kastrup J; Steinbruchel D; Thorén P; Hansson GK
Article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2004;24(3):551-557

Human evidence that the cystatin C gene is implicated in focal progression of coronary artery disease

Eriksson P; Deguchi H; Samnegård A; Lundman P; Boquist S; Tornvall P; Ericsson CG; Bergstrand L; Hansson LO; Ye S; Hamsten A
Article: INTERNATIONAL JOURNAL OF OBESITY. 2004;28(2):185-190

Relationship between β-2 adrenoceptor gene haplotypes and adipocyte lipolysis in women

Eriksson P; Dahlman I; Rydén M; Hoffstedt J; Arner P
Article: MATRIX BIOLOGY. 2004;22(7):557-560

High-density lipoprotein subfraction 3 decreases ADAMTS-1 expression induced by lipopolysaccharide and tumor necrosis factor-α in human endothelial cells

Norata GD; Björk H; Hamsten A; Catapano AL; Eriksson P
Article: JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM. 2004;89(1):392-399

Genetic and structural evaluation of fatty acid transport protein-4 in relation to markers of the insulin resistance syndrome

Gertow K; Bellanda M; Eriksson P; Boquist S; Hamsten A; Sunnerhagen M; Fisher RM
Article: BLOOD COAGULATION & FIBRINOLYSIS. 2003;14(8):749-753

No evidence that the PLA1/PLA2 polymorphism of platelet glycoprotein IIIa is implicated in angiographically characterized coronary atherosclerosis and premature myocardial infarction

Lagercrantz J; Bergman M; Lundman P; Tornvall P; Hjemdahl P; Hamsten A; Eriksson P
Article: CARDIOVASCULAR RESEARCH. 2003;59(1):169-180

Gene expression and intracellular pathways involved in endothelial dysfunction induced by VLDL and oxidised VLDL

Norata GD; Pirillo A; Callegari E; Hamsten A; Catapano AL; Eriksson P
Article: INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE. 2003;12(1):73-78

Effects of HDL₃ on the expression of matrix-degrading proteases in human endothelial cells

Norata GD; Pellegatta F; Hamsten A; Catapano AL; Eriksson P
Article: JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY. 2003;41(12):2130-2137

Influences of matrix metalloproteinase-3 gene variation on extent of coronary atherosclerosis and risk of myocardial infarction

Beyzade S; Zhang SL; Wong YK; Day INM; Eriksson P; Ye S
Article: MOLECULAR HUMAN REPRODUCTION. 2003;9(5):271-277

Epithelial expression of matrix metalloproteinase-26 is elevated at mid-cycle in the human endometrium

Pilka R; Whatling C; Domanski H; Hansson S; Casslén B
Article: ATHEROSCLEROSIS. 2003;167(2):265-273

A common polymorphism in the fatty acid transport protein-1 gene associated with elevated post-prandial lipaemia and alterations in LDL particle size distribution

Gertow K; Skoglund-Andersson C; Eriksson P; Boquist S; Orth-Gomér K; Schenck-Gustafsson K; Hamsten A; Fisher RM
Article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2003;23(4):637-643

Evidence that peroxisome proliferator-activated receptor delta influences cholesterol metabolism in men

Skogsberg J; Kannisto K; Cassel TN; Hamsten A; Eriksson P; Ehrenborg E
Article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2003;23(4):688-694

Regulation of plasma PAI-1 concentrations in HAART-associated lipodystrophy during rosiglitazone therapy

Yki-Järvinen H; Sutinen J; Silveira A; Korsheninnikova E; Fisher RM; Kannisto K; Ehrenborg E; Eriksson P; Hamsten A
Article: HORMONE AND METABOLIC RESEARCH. 2002;34(11-12):698-702

Glucocorticoid-regulated adipose tissue secretion of PAI-1, but not IL-6, TNFα or leptin in vivo

Uddén J; Eriksson P; Hoffstedt J
Article: BIOTECHNIQUES. 2002;33(5):1104-1108

Molecular haplotyping by pyrosequencing™

Odeberg J; Holmberg K; Eriksson P; Uhlén M
Article: AMERICAN JOURNAL OF PATHOLOGY. 2002;161(3):939-945

Differential expression of cysteine and aspartic proteases during progression of atherosclerosis in apolipoprotein E-deficient mice

Jormsjö S; Wuttge DM; Sirsjö A; Whatling C; Hamsten A; Stemme S; Eriksson P
Article: HORMONE AND METABOLIC RESEARCH. 2002;34(7):355-359

A polymorphism in the leptin promoter region (-2548 G/A) influences gene expression and adipose tissue secretion of leptin

Hoffstedt J; Eriksson P; Mottagui-Tabar S; Arner P
Article: EUROPEAN JOURNAL OF VASCULAR AND ENDOVASCULAR SURGERY. 2002;23(5):421-425

The influence of 4G/5G polymorphism in the plasminogen activator inhibitor-1 gene promoter on the incidence, growth and operative risk of abdominal aortic aneurysm

Jones K; Powell J; Brown L; Greenhalgh R; Jormsjö S; Eriksson P
Article: METABOLISM-CLINICAL AND EXPERIMENTAL. 2002;51(3):327-333

Linoleic acid-stimulated vascular adhesion molecule-1 expression in endothelial cells depends on nuclear factor-κB activation

Dichtl W; Ares MPS; Jönson AN; Jovinge S; Pachinger O; Giachelli CM; Hamsten A; Eriksson P; Nilsson J
Article: EUROPEAN HEART JOURNAL. 2002;23(5):376-383

Plasma tumour necrosis factor-α and early carotid atherosclerosis in healthy middle-aged men

Skoog T; Dichtl W; Boquist S; Skoglund-Andersson C; Karpe F; Tang R; Bond MG; de Faire U; Nilsson J; Eriksson P; Hamsten A
Article: INTERNATIONAL JOURNAL OF OBESITY. 2001;25(11):1599-1603

The Arg 389 Gly β₁-adrenergic receptor gene polymorphism and human fat cell lipolysis

Rydén M; Hoffstedt J; Eriksson P; Bringman S; Arner P
Article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2001;21(11):1834-1839

Allele-specific regulation of matrix metalloproteinase-7 promoter activity is associated with coronary artery luminal dimensions among hypercholesterolemic patients

Jormsjö S; Whatling C; Walter DH; Zeiher AM; Hamsten A; Eriksson P
Article: DIABETOLOGIA. 2001;44(10):1268-1273

Fatty acid binding protein expression in different adipose tissue depots from lean and obese individuals

Fisher RM; Eriksson P; Hoffstedt J; Hotamisligil GS; Thörne A; Rydén M; Hamsten A; Arner P
Article: AMERICAN JOURNAL OF PATHOLOGY. 2001;159(2):417-423

Expression of interleukin-15 in mouse and human atherosclerotic lesions

Wuttge DM; Eriksson P; Sirsjö A; Hansson GK; Stemme S
Article: DIABETES. 2001;50(7):1522-1530

Transcriptional regulation of plasminogen activator inhibitor type I gene by insulin - Insights into the signaling pathway

Banfi C; Eriksson P; Giandomenico G; Mussoni L; Sironi L; Hamsten A; Tremoli E
Article: MOLECULAR MEDICINE. 2001;7(6):383-392

Gene expression in atherosclerotic lesion of ApoE deficient mice

Wuttge DM; Sirsjö A; Eriksson P; Stemme S
Article: ATHEROSCLEROSIS. 2001;154(3):703-711

Polymorphisms in the thrombopoietin gene are associated with risk of myocardial infarction at a young age

Webb KE; Martin JF; Hamsten A; Eriksson P; Iacoviello L; Gattone M; Donati MB; Di Castelnuovo A; Erusalimsky J; Humphries SE
Article: THROMBOSIS AND HAEMOSTASIS. 2000;84(4):706-711

In vivo stimulation of vascular plasminogen activator inhibitor-1 production by very low-density lipoprotein involves transcription factor binding to a VLDL-responsive element

Dichtl W; Ares MPS; Stollenwerk M; Giachelli CM; Scatena M; Hamsten A; Eriksson P; Nilsson J
Journal article: ATHEROSCLEROSIS. 2000;151(1):79

Fatty acid binding proteins in different human adipose tissue depots: Relationships to serum insulin concentrations

Fisher RM; Eriksson P; Hoffstedt J; Hamsten A; Arner P
Journal article: ATHEROSCLEROSIS. 2000;151(1):159

Genetic regulation of the MMP-7 and MMP-12 gene expression

Jormsjö S; Ye S; Moritz J; Burt B; Henney A; Hamsten A; Eriksson P
Article: JOURNAL OF INTERNAL MEDICINE. 2000;247(6):651-656

The Q/E27 polymorphism in the β₂-adrenoceptor gene is associated with increased body weight and dyslipoproteinaemia involving triglyceride-rich lipoproteins

Ehrenborg E; Skogsberg J; Ruotolo G; Large V; Eriksson P; Arner P; Hamsten A
Article: CIRCULATION RESEARCH. 2000;86(9):998-1003

Allele-specific regulation of matrix metalloproteinase-12 gene activity is associated with coronary artery luminal dimensions in diabetic patients with manifest coronary artery disease

Jormsjö S; Ye S; Moritz J; Walter DH; Dimmeler S; Zeiher AM; Henney A; Hamsten A; Eriksson P
Article: THROMBOSIS AND HAEMOSTASIS. 2000;83(4):545-548

Regional variation in plasminogen activator inhibitor-1 expression in adipose tissue from obese individuals

Eriksson P; Van Harmelen V; Hoffstedt J; Lundquist P; Vidal H; Stemme V; Hamsten A; Arner P; Reynisdottir S
Article: THROMBOSIS AND HAEMOSTASIS. 2000;83(2):304-308

Role of gender and genetic variance in plasminogen activator inhibitor-1 secretion from human adipose tissue

Van Harmelen V; Wahrenberg H; Eriksson P; Arner P
Article: DIABETOLOGIA. 2000;43(1):117-120

Excessive fat accumulation is associated with the TNFα-308 G/A promoter polymorphism in women but not in men

Hoffstedt J; Eriksson P; Hellström L; Rössner S; Rydén M; Arner P
Article: FREE RADICAL RESEARCH. 1999;31(6):503-512

Hydrogen peroxide induces mRNA for tumour necrosis factor α in human endothelial cells

Valen G; Erl W; Eriksson P; Wuttge D; Paulsson G; Hansson GK
Article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 1999;19(12):3063-3070

Two common, functional polymorphisms in the promoter region of the β-fibrinogen gene contribute to regulation of plasma fibrinogen concentration

van't Hooft FM; von Bahr SJF; Silveira A; Iliadou A; Eriksson P; Hamsten A
Article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 1999;19(12):3025-3032

Oxidized LDL and lysophosphatidylcholine stimulate plasminogen activator inhibitor-1 expression in vascular smooth muscle cells

Dichtl W; Stiko A; Eriksson P; Goncalves I; Calara F; Banfi C; Ares MPS; Hamsten A; Nilsson J
Article: HUMAN GENETICS. 1999;105(5):418-423

Genetic variation at the matrix metalloproteinase-9 locus on chromosome 20q12.2-13.1

Zhang BP; Henney A; Eriksson P; Hamsten A; Watkins H; Ye S
Article: JOURNAL OF LIPID RESEARCH. 1999;40(9):1686-1694

A functional polymorphism in the apolipoprotein B promoter that influences the level of plasma low density lipoprotein

van 't Hooft FM; Jormsjö S; Lundahl B; Tornvall P; Eriksson P; Hamsten A
Article: HUMAN MOLECULAR GENETICS. 1999;8(8):1443-1449

A common functional polymorphism (C→A substitution at position-863) in the promoter region of the tumour necrosis factor-α (TNF-α) gene associated with reduced circulating levels of TNF-α

Skoog T; van't Hooft FM; Kallin B; Jovinge S; Boquist S; Nilsson J; Eriksson P; Hamsten A
Article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 1999;19(6):1577-1581

Effects of fibrate compounds on expression of plasminogen activator inhibitor-1 by cultured endothelial cells

Nilsson L; Takemura T; Eriksson P; Hamsten A
Article: BLOOD. 1999;93(10):3432-3441

Two common functional polymorphisms in the promoter region of the coagulation factor VII gene determining plasma factor VII activity and mass concentration

van't Hooft FM; Silveira A; Tornvall P; Iliadou A; Ehrenborg E; Eriksson P; Hamsten A
Article: CIRCULATION RESEARCH. 1999;84(9):1085-1094

Very low-density lipoprotein activates nuclear factor-κB in endothelial cells

Dichtl W; Nilsson L; Goncalves I; Ares MPS; Banfi C; Calara F; Hamsten A; Eriksson P; Nilsson J
Article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 1999;19(5):1354-1360

Effects of native, triglyceride-enriched, and oxidatively modified LDL on plasminogen activator inhibitor-1 expression in human endothelial cells

Allison BA; Nilsson L; Karpe F; Hamsten A; Eriksson P
Article: JOURNAL OF LIPID RESEARCH. 1999;40(5):913-919

VLDL activation of plasminogen activator inhibitor-1 (PAI-1) expression:: involvement of the VLDL receptor

Nilsson L; Gåfvels M; Musakka L; Ensler K; Strickland DK; Angelin B; Hamsten A; Eriksson P
Article: CIRCULATION. 1999;99(14):1788-1794

Functional polymorphism in the regulatory region of gelatinase B gene in relation to severity of coronary atherosclerosis

Zhang BP; Ye S; Herrmann SM; Eriksson P; de Maat M; Evans A; Arveiler D; Luc G; Cambien F; Hamsten A; Watkins H; Henney AM
Article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 1998;18(11):1679-1685

Unsaturated fatty acids increase plasminogen activator inhibitor-1 expression in endothelial cells

Nilsson L; Banfi C; Diczfalusy U; Tremoli E; Hamsten A; Eriksson P
Article: DIABETES. 1998;47(6):913-917

Leptin secretion from subcutaneous and visceral adipose tissue in women

Van Harmelen V; Reynisdottir S; Eriksson P; Thörne A; Hoffstedt J; Lönnqvist F; Arner P
Article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 1998;18(5):756-761

A common functional polymorphism in the promoter region of the microsomal triglyceride transfer protein gene influences plasma LDL levels

Karpe F; Lundahl B; Ehrenborg E; Eriksson P; Hamsten A
Journal article: GROWTH HORMONE & IGF RESEARCH. 1998;8:201

Growth hormone and insulin-like growth factor I improve cardiac function and regulate expression of the Fas receptor in rats after experimental myocardial infarction

Tivesten Å; Matejka G; Caidahl K; Kujacic V; Eriksson P; Sun XY; Brantsing C; Hedner T; Bengtsson B-Å; Isgaard J
Article: DIABETOLOGIA. 1998;41(1):65-71

Adipose tissue secretion of plasminogen activator inhibitor-1 in non-obese and obese individuals

Eriksson P; Reynisdottir S; Lönnqvist F; Stemme V; Hamsten A; Arner P
Article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 1998;18(1):20-26

Very-low-density lipoprotein response element in the promoter region of the human plasminogen activator inhibitor-1 gene implicated in the impaired fibrinolysis of hypertriglyceridemia

Eriksson P; Nilsson L; Karpe F; Hamsten A
Article: JOURNAL OF CLINICAL INVESTIGATION. 1997;100(12):3005-3013

Human beta-2 adrenoceptor gene polymorphisms are highly frequent in obesity and associate with altered adipocyte beta-2 adrenoceptor function

Large V; Hellström L; Reynisdottir S; Lönnqvist F; Eriksson P; Lannfelt L; Arner P
Journal article: FIBRINOLYSIS AND PROTEOLYSIS. 1997;11:28

97 Adipose tissue secretion of plasminogen activator inhibitor-1 in non-obese and obese individuals

Eriksson P; Reynisdottir S; Lönnqvist F; Stemme V; Hamsten A; Arner P
Article: MOLECULAR HUMAN REPRODUCTION. 1997;3(9):781-787

Differential regulation of the plasminogen activator inhibitor-1 (PAI-1) gene expression by growth factors and progesterone in human endometrial stromal cells

Sandberg T; Eriksson P; Gustavsson B; Casslen B
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 1996;271(22):13055-13060

Progression of coronary atherosclerosis is associated with a common genetic variant of the human stromelysin-1 promoter which results in reduced gene expression

Ye S; Eriksson P; Hamsten A; Kurkinen M; Humphries SE; Henney AM
Article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 1995;15(10):1584-1590

OXIDIZED LDL INDUCES TRANSCRIPTION FACTOR ACTIVATOR PROTEIN-1 BUT INHIBITS ACTIVATION OF NUCLEAR FACTOR-KAPPA-B IN HUMAN VASCULAR SMOOTH-MUSCLE CELLS

ARES MPS; KALLIN B; ERIKSSON P; NILSSON J
Article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 1995;15(5):655-664

COAGULATION-FACTOR-VII MASS AND ACTIVITY IN YOUNG MEN WITH MYOCARDIAL-INFARCTION AT A YOUNG AGE - ROLE OF PLASMA-LIPOPROTEINS AND FACTOR-VII GENOTYPE

MOOR E; SILVEIRA A; VANTHOOFT F; SUONTAKA AM; ERIKSSON P; BLOMBACK M; HAMSTEN A
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 1995;92(6):1851-1855

ALLELE-SPECIFIC INCREASE IN BASAL TRANSCRIPTION OF THE PLASMINOGEN-ACTIVATOR INHIBITOR-1 GENE IS ASSOCIATED WITH MYOCARDIAL-INFARCTION

ERIKSSON P; KALLIN B; VANTHOOFT FM; BAVENHOLM P; HAMSTEN A
Journal article: CURRENT OPINION IN LIPIDOLOGY. 1994;5(5):382-389

Relationships of thrombosis and fibrinolysis to atherosclerosis.

Hamsten A; Eriksson P; Karpe F; Silveira A
Journal article: FIBRINOLYSIS. 1994;8:253-262

FIBRINOLYSIS AND ATHEROSCLEROSIS - AN UPDATE

HAMSTEN A; ERIKSSON P
Journal article: FIBRINOLYSIS AND PROTEOLYSIS. 1994;8:79

Functional studies of an 4G/5G polymorphism in the PAI-1 promoter region which is associated with myocardial infarction at a young age

Eriksson P; Kallin B; van 't Hooft F; Hamsten A
Journal article: FEBS JOURNAL. 1993;215(2):505-511

THE GLUCOCORTICOID RECEPTOR ACTS AS AN ANTIREPRESSOR IN RECEPTOR-DEPENDENT IN-VITRO TRANSCRIPTION

ERIKSSON P; WRANGE O
Journal article: JOURNAL OF STRUCTURAL BIOLOGY. 1991;107(1):48-55

THE GLUCOCORTICOID RECEPTOR IN HOMODIMERIC AND MONOMERIC FORM VISUALIZED BY ELECTRON-MICROSCOPY

ERIKSSON P; DANEHOLT B; WRANGE O
Journal article: JOURNAL OF BIOLOGICAL CHEMISTRY. 1990;265(28):17222-17229

QUANTITATIVE-ANALYSIS OF THE GLUCOCORTICOID RECEPTOR-DNA INTERACTION AT THE MOUSE MAMMARY-TUMOR VIRUS GLUCOCORTICOID RESPONSE ELEMENT

ERLMANN T; ERIKSSON P; WRANGE O
Journal article: JOURNAL OF BIOLOGICAL CHEMISTRY. 1990;265(6):3535-3542

PROTEIN-PROTEIN CONTACTS IN THE GLUCOCORTICOID RECEPTOR HOMODIMER INFLUENCE ITS DNA-BINDING PROPERTIES

ERIKSSON P; WRANGE O
Journal article: MOLECULAR AND CELLULAR BIOLOGY. 1989;9(12):5305-5314

GLUCOCORTICOID RECEPTOR-BINDING TO A SPECIFIC DNA-SEQUENCE IS REQUIRED FOR HORMONE-DEPENDENT REPRESSION OF PRO-OPIOMELANOCORTIN GENE-TRANSCRIPTION

DROUIN J; TRIFIRO MA; PLANTE RK; NEMER M; ERIKSSON P; WRANGE O
Journal article: JOURNAL OF BIOLOGICAL CHEMISTRY. 1989;264(9):5253-5259

THE PURIFIED ACTIVATED GLUCOCORTICOID RECEPTOR IS A HOMODIMER

WRANGE O; ERIKSSON P; PERLMANN T
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All other publications

Book chapter: AORTIC VALVE DISEASE - RECENT ADVANCES. 2024;p.

Ascending Aortic Aneurysm in Relation to Aortic Valve Phenotype

Freiholtz D; Eriksson P; M. Björck H
Preprint: MEDRXIV. 2024;MEDRXIV

A functional genomic framework to elucidate novel causal non-alcoholic fatty liver disease genes.

Saliba-Gustafsson P; Justesen JM; Ranta A; Sharma D; Bielczyk-Maczynska E; Li J; Najmi LA; Apodaka M; Aspichueta P; Björck HM; Eriksson P; Franco-Cereceda A; Gloudemans M; Mujica E; den Hoed M; Assimes TL; Quertermous T; Carcamo-Orive I; Park CY; Knowles JW
Conference publication: ATHEROSCLEROSIS. 2023;379:s5

FOXC1 CONTROLS SMOOTH MUSCLE CELL ACTIVATION IN VASCULAR DISEASE

Matic L; Rykaczewska U; Suur B; Gaelle A; Quanyi Z; Xiang Z; Narayanan S; Hedman A; Lengquist M; Kronqvist M; Vuckovic S; Sward K; Razuvaev A; Malarstig A; Eriksson P; Miller C; Quertermous T; Hedin U
Conference publication: JOURNAL OF HEPATOLOGY. 2023;78:s756-s757

Statins regulate PNPLA3 through a mechanism that requires SREBF2 in human liver cells

Ahmed O; Shavva VS; Dai W; Tarnawski L; Malin S; Franco-Cereceda A; Eriksson P; Bjorck H; Olofsson P
Preprint: RESEARCH SQUARE. 2023

Proteomic analysis of 92 circulating proteins and their effects in cardiometabolic diseases

Carland C; Png G; Malarstig A; Kho PF; Gustafsson S; Michaelsson K; Lind L; Tsafantakis E; Karaleftheri M; Dedoussis G; Ramisch A; Macdonald-Dunlop E; Klaric L; Joshi PK; Chen Y; Björck HM; Eriksson P; Carrasco-Zanini J; Wheeler E; Suhre K; Gilly A; Zeggini E; Viñuela A; Dermitzakis ET; Wilson JF; Langenberg C; Thareja G; Halama A; Schmidt F; Consortium S; Zanetti D; Assimes T
Preprint: BIORXIV. 2022

Kupffer cells dictate hepatic responses to the atherogenic dyslipidemic insult

Hellberg S; Ahmed O; Zhang Y; Di Nunzio G; Björck HM; Francis R; Fagerberg L; Gisterå A; Zhang X; Metso J; Manfé V; Soto Y; Franco-Cereceda A; Eriksson P; Jauhiainen M; Olofsson PS; Malin SG
Conference publication: AORTA. 2022;10:a1-a56

Possible Role of SPP1 in Degenerative Ascending Aortic Aneurysm Formation

Bergman O; Freiholtz D; Poujade F-A; Granath C; Lång K; Ohlsson C; Franco-Cereceda A; Eriksson P; Björck H
Conference publication: ATHEROSCLEROSIS. 2022;355:E68-E69

THE ROLE OF RARE ENHANCER VARIANTS IN BICUSPID AORTIC VALVE PATHOLOGY

Zhigulev A; Lang K; Pradhananga S; Spalinskas R; Franco-Cereceda A; Bjorck H; Eriksson P; Sahlen P
Preprint: RESEARCH SQUARE. 2021

Clinical Classifiers to Identify Ascending Aortic Dilatation in Patients With Bicuspid Versus Tricuspid Aortic Valves

Gaye B; Vignac M; Gådin JR; Ladouceur M; Caidahl K; Olsson C; Franco-Cereceda A; Eriksson P; Björck HM
Preprint: MEDRXIV. 2021

Mapping genetic determinants of 184 circulating proteins in 26,494 individuals to connect proteins and diseases

Macdonald-Dunlop E; Klarić L; Folkersen L; Timmers PRHJ; Gustafsson S; Zhao JH; Eriksson N; Richmond A; Enroth S; Mattsson-Carlgren N; Zhernakova DV; Kalnapenkis A; Magnusson M; Wheeler E; Hwang S-J; Chen Y; Morris AP; Prins B; Võsa U; Wareham NJ; Danesh J; Sundstrom J; Gigante B; Baldassarre D; Strawbridge RJ; Campbell H; Gyllensten U; Yao C; Zanetti D; Assimes TL; Eriksson P; Levy D; Langenberg C; Smith JG; Esko T; Fu J; Hansson O; Johansson Å; Hayward C; Wallentin L; Siegbahn A; Lind L; Butterworth AS; Michaëlsson K; Peters JE; Mälarstig A; Joshi PK; Wilson JF
Conference publication: ATHEROSCLEROSIS. 2021;331:E18

PRENYLCYSTEINE OXIDASE 1, A NOVEL PLAYER IN ATHEROSCLEROSIS

Banfi C; Baetta R; Barbieri SS; Brioschi M; Guarino A; Ghilardi S; Sandrini L; Polvani G; Bergman O; Eriksson P; Tremoli E
Conference publication: ATHEROSCLEROSIS. 2021;331:E4

PROPROTEIN CONVERTASE SUBTILISIN/KEXIN 6 IS INVOLVED IN LIPID METABOLISM IN LIVER AND ADIPOSE TISSUE

Suur BE; Chemaly M; Jin H; Kronqvist M; Lengquist M; Van der Laan SW; Lleal MS; Malarstig A; Pasterkamp G; Eriksson P; Hedin U; Ketelhuth DFJ; Hurt-Camejo E; Matic L
Preprint: RESEARCH SQUARE. 2021

The VE-cadherin/AmotL2 mechanosensory pathway suppresses aortic inflammation and the formation of abdominal aortic aneurysms

Zhang Y; Hutterer E; Hultin S; Bergman O; Forteza M; Andonovic Z; Ketelhuth D; Roy J; Eriksson P; Holmgren L
Preprint: BIORXIV. 2021

The VE-cadherin/AmotL2 mechanosensory pathway suppresses aortic inflammation and the formation of abdominal aortic aneurysms

Zhang Y; Hutterer E; Hultin S; Bergman O; Forteza MJ; Andonovic Z; Ketelhuth DFJ; Roy J; Eriksson P; Holmgren L
Preprint: MEDRXIV. 2021;MEDRXIV

Mendelian randomisation identifies alternative splicing of the FAS death receptor as a mediator of severe COVID-19.

Klaric L; Gisby JS; Papadaki A; Muckian MD; Macdonald-Dunlop E; Zhao JH; Tokolyi A; Persyn E; Pairo-Castineira E; Morris AP; Kalnapenkis A; Richmond A; Landini A; Hedman ÅK; Prins B; Zanetti D; Wheeler E; Kooperberg C; Yao C; Petrie JR; Fu J; Folkersen L; Walker M; Magnusson M; Eriksson N; Mattsson-Carlgren N; Timmers PRHJ; Hwang S-J; Enroth S; Gustafsson S; Vosa U; Chen Y; Siegbahn A; Reiner A; Johansson Å; Thorand B; Gigante B; Hayward C; Herder C; Gieger C; Langenberg C; Levy D; Zhernakova DV; Smith JG; Campbell H; Sundstrom J; Danesh J; Michaëlsson K; Suhre K; Lind L; Wallentin L; Padyukov L; Landén M; Wareham NJ; Göteson A; Hansson O; Eriksson P; Strawbridge RJ; Assimes TL; Esko T; Gyllensten U; Baillie JK; Paul DS; Joshi PK; Butterworth AS; Mälarstig A; Pirastu N; Wilson JF; Peters JE
Corrigendum: NATURE COMMUNICATIONS. 2021;12(1):995

Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability (vol 12, 24, 2021)

Lagou V; Magi R; Hottenga J-J; Grallert H; Perry JRB; Bouatia-Naji N; Marullo L; Rybin D; Jansen R; Min JL; Dimas AS; Ulrich A; Zudina L; Gadin JR; Jiang L; Faggian A; Bonnefond A; Fadista J; Stathopoulou MG; Isaacs A; Willems SM; Navarro P; Tanaka T; Jackson AU; Montasser ME; O'Connell JR; Bielak LF; Webster RJ; Saxena R; Stafford JM; St Pourcain B; Timpson NJ; Salo P; Shin S-Y; Amin N; Smith AV; Li G; Verweij N; Goel A; Ford I; Johnson PCD; Johnson T; Kapur K; Thorleifsson G; Strawbridge RJ; Rasmussen-Torvik LJ; Esko T; Mihailov E; Fall T; Fraser RM; Mahajan A; Kanoni S; Giedraitis V; Kleber ME; Silbernagel G; Meyer J; Mueller-Nurasyid M; Ganna A; Sarin A-P; Yengo L; Shungin D; Luan J; Horikoshi M; An P; Sanna S; Boettcher Y; Rayner NW; Nolte IM; Zemunik T; van Iperen E; Kovacs P; Hastie ND; Wild SH; McLachlan S; Campbell S; Polasek O; Carlson O; Egan J; Kiess W; Willemsen G; Kuusisto J; Laakso M; Dimitriou M; Hicks AA; Rauramaa R; Bandinelli S; Thorand B; Liu Y; Miljkovic I; Lind L; Doney A; Perola M; Hingorani A; Kivimaki M; Kumari M; Bennett AJ; Groves CJ; Herder C; Koistinen HA; Kinnunen L; de Faire U; Bakker SJL; Uusitupa M; Palmer CNA; Jukema JW; Sattar N; Pouta A; Snieder H; Boerwinkle E; Pankow JS; Magnusson PK; Krus U; Scapoli C; de Geus EJCN; Blueher M; Wolffenbuttel BHR; Province MA; Abecasis GR; Meigs JB; Hovingh GK; Lindstroem J; Wilson JF; Wright AF; Dedoussis GV; Bornstein SR; Schwarz PEH; Toenjes A; Winkelmann BR; Boehm BO; Maerz W; Metspalu A; Price JF; Deloukas P; Koerner A; Lakka TA; Keinanen-Kiukaanniemi SM; Saaristo TE; Bergman RN; Tuomilehto J; Wareham NJ; Langenberg C; Mannisto S; Franks PW; Hayward C; Vitart V; Kaprio J; Visvikis-Siest S; Balkau B; Altshuler D; Rudan I; Stumvoll M; Campbell H; van Duijn CM; Gieger C; Illig T; Ferrucci L; Pedersen NL; Pramstaller PP; Boehnke M; Frayling TM; Shuldiner AR; Peyser PA; Kardia SLR; Palmer LJ; Penninx BW; Meneton P; Harris TB; Navis G; van der Harst P; Smith GD; Forouhi NG; Loos RJF; Salomaa V; Soranzo N; Boomsma DI; Groop L; Tuomi T; Hofman A; Munroe PB; Gudnason V; Siscovick DS; Watkins H; Lecoeur C; Vollenweider P; Franco-Cereceda A; Eriksson P; Jarvelin M-R; Stefansson K; Hamsten A; Nicholson G; Karpe F; Dermitzakis ET; Lindgren CM; McCarthy MI; Froguel P; Kaakinen MA; Lyssenko V; Watanabe RM; Ingelsson E; Florez JC; Dupuis J; Barroso I; Morris AP; Prokopenko I
Preprint: MEDRXIV. 2020

The overlap of genetic susceptibility to schizophrenia and cardiometabolic disease can be used to identify metabolically different groups of individuals

Strawbridge R; Johnston K; Bailey M; Baldasarre D; Cullen B; Eriksson P; DeFaire U; Ferguson A; Gigante B; Giral P; Graham N; Hamsten A; Humphries S; Kurl S; Lyall D; Lyall L; Pirro M; Pell J; Savonen K; Sennblad B; Smit A; Tremoli E; Tomainen T-P; Veglia F; Ward J; Smith D
Conference publication: HUMAN HEREDITY. 2020;84(4-5):216-217

Genomic Architecture of 184 Plasma Proteins in 18,884 Individuals: the SCALLOP Consortium

Macdonald-Dunlop E; Joshi P; Peters J; Folkersen L; Ingelsson E; Timmers P; Michaelsson K; Gustafsson S; Enroth S; Johansson A; Smith G; Zhernakova D; Siegbahn A; Kalnapenkis A; Eriksson N; Wheeler E; Fu J; Franke L; Hayward C; Wallentin L; Esko T; Zeggini E; Teunissen C; Langenberg C; Hansson O; Eriksson P; Gyllensten U; Butterworth A; Malarstig A; Wilson J
Conference publication: ATHEROSCLEROSIS. 2020;315:E22-E23

PLAYS AN IMPORTANT ROLE IN THE REGULATION OF VASCULAR SMOOTH MUSCLE CELL PHENOTYPE

Ehrenborg E; Paloschi V; Goncalves I; Saliba-Gustafsson P; Werngren O; Matic L; Skogsberg J; Jin H; Ketelhuth DFJ; Maegdefessel L; Hedin U; Eriksson P; Magne J
Conference publication: ATHEROSCLEROSIS. 2019;287:E55-E56

SUBCLINICAL ATHEROSCLEROSIS AND ITS PROGRESSION IS MODULATED BY PLIN2 THROUGH A FEED-FORWARD LOOP BETWEEN LXR AND AUTOPHAGY

Pourteymour S; Gustafsson PS; Pedrelli M; Gertow K; Werngren O; Janas V; Baldassarre D; Tremoli E; De Faire U; Humphries S; Hamsten A; Goncalves I; Orho-Melander M; Franco-Cereceda A; Boren J; Eriksson P; Magne J; Ewa E; Parini P
Meeting abstract: ATHEROSCLEROSIS. 2019;287:E287

GENDER DIFFERENCES IN PATIENTS WITH BICUSPID AORTIC VALVES

Vignac M; Gaye B; Bjorck HM; Olsson C; Franco-Cereceda A; Eriksson P
Meeting abstract: ATHEROSCLEROSIS. 2019;287:E277

PREDICTION OF THE DEVELOPMENT OF AORTIC DILATATION IN PATIENTS WITH BICUSPID (BAV) VERSUS TRICUSPID (TAV) AORTIC VALVES.

Gaye B; Vignac M; Bjorck HM; Olsson C; Franco-Cereceda A; Eriksson P
Meeting abstract: CIRCULATION. 2019;139

Prediction of the Development of Aortopathy in Patients With Bicuspid Aortic Valves

Gaye B; Bjorck HM; Ladouceur M; Vignac M; Olsson C; Cereceda AF; Eriksson P
Conference publication: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2019;39

Transcriptomic Profiling of Experimental Arterial Injury Reveals Temporal Dynamics and New Mechanisms in Vascular Healing Response

Matic L; Roehl S; Rykaczewska U; Seime T; Suur B; Diez MG; Gadin JR; Sergushichev AA; Wirka R; Lengquist M; Kronqvist M; Bergman O; Odeberg J; Lindeman JH; Quertermous T; Hamsten A; Eriksson P; Hedin U; Razuvaev A
Conference publication: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2019;39

Expression Landscape of the Proprotein Convertase Subtilisin/Kexin Family in Vascular Disease

Suur BE; Liljeqvist ML; Bergman O; Li Y; Lengquist M; Razuvaev A; Odeberg J; Paulsson-Berne G; Hansson GK; Maegdefessel L; Eriksson P; Hedin U; Ketelhuth DF; Roy J; Matic L
Conference publication: EUROPEAN HEART JOURNAL. 2019;40:334

Subclinical atherosclerosis and its progression are modulated by perilipin-2 through a feed-forward loop between LXR and autophagy

Ehrenborg E; Gustafsson PS; Pedrelli M; Gertow K; Pourteymour S; Baldassarre D; Tremoli E; De Faire U; Humphries SE; Goncalves I; Orho-Melander M; Boren J; Eriksson P; Magne J; Parini P
Conference publication: EUROPEAN HEART JOURNAL. 2019;40:4193

Upregulation of protein and gene expression of arginase-1 in patients with ST elevation myocardial infarction

Tengbom J; Cederstrom S; Verouhis D; Sorensson P; Bohm F; Saleh N; Jernberg T; Lundman P; Eriksson P; Gabrielsen A; Caidahl K; Persson J; Folkersen L; Tornvall P; Pernow J
Review: FRONTIERS IN CARDIOVASCULAR MEDICINE. 2019;6:182

Endothelial/Epithelial Mesenchymal Transition in Ascending Aortas of Patients With Bicuspid Aortic Valve

Maleki S; Poujade F-A; Bergman O; Gadin JR; Simon N; Lang K; Franco-Cereceda A; Body SC; Bjorck HM; Eriksson P
Conference publication: EUROPEAN HEART JOURNAL. 2019;40:674

Zirconium-89 labelled probe for molecular imaging of inflammation in experimental atherosclerosis

Ahmed M; Tegnebratt T; Tran T; Damberg P; Bone D; Lu L; Gistera A; Tarnawski L; Hedin U; Eriksson P; Holmin S; Gustafsson B; Caidahl K
Preprint: BIORXIV. 2018

High-resolution regulatory maps connect cardiovascular risk variants to disease related pathways

Åkerborg Ö; Spalinskas R; Pradhananga S; Anil A; Höjer P; Poujade F-A; Folkersen L; Eriksson P; Sahlén P
Conference publication: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2018;38

Effect of Intraluminal Thrombus on the Transcriptome of the Tunica Media and Adventitia in Abdominal Aortic Aneurysms

Liljeqvist ML; Hultgren R; Villard C; Kronqvist M; Eriksson P; Roy J
Conference publication: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2018;38

Pnpla2 Influences Secretion of Triglyceride-rich Lipoproteins but Does Not Affect Lipid-droplet Metabolism of Human Hepatoma Cells

Taxiarchis A; Mahdessian H; Silveira A; Eriksson P; Fisher R; van 't Hooft FM
Meeting abstract: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2018;38

H19 Induces Abdominal Aortic Aneurysm Development and Progression

Li DY; Busch A; Jin H; Chernogubova E; Pelisek J; Eriksson P; Roy J; Hofmann P; Boon R; Spin J; Tsao P; Maegdefessel L
Meeting abstract: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2018;38

Repression of Map1lc3a During Atherosclerosis Progression Plays an Important Role in the Regulation of Vascular Smooth Muscle Cell Phenotype

Magne J; Paloschi V; Goncalves I; Saliba-Gustafsson P; Skogsberg J; Razuvaev A; Jin H; Li Y; Ketelhuth DFJ; Maegdefessel L; Hedin U; Eriksson P; Ehrenborg E
Meeting abstract: CARDIOVASCULAR RESEARCH. 2018;114:S141

Regulation of purinergic signaling in response to arterial injury

Golovkin A; Fedorov A; Hamsten A; Eriksson P; Hedin U; Razuvaev A; Kostareva A
Conference publication: CARDIOVASCULAR RESEARCH. 2018;114:S47

DNA methylation in bicuspid aortic valve aortopathy: potential contribution of oscillatory flow to an epithelial-to-mesenchymal transition signature

Bjorck H; Du L; Pulignani S; Paloschi V; Lundstromer K; Kostina A; Evangelista A; Maleki S; Franco-Cereceda A; Eriksson P
Conference publication: CARDIOVASCULAR RESEARCH. 2018;114:S84

Regulation of LTBP expression as a modulator of TGFb availability in patients with BAV

Poujade F-A; Du L; Paloschi V; Eriksson P
Conference publication: CARDIOVASCULAR RESEARCH. 2018;114:S83

Notch signaling pathway is attenuated in aortic endothelial cells of patients with aortic pathologies associated with bicuspid aortic valve

Kostina A; Kiselev A; Bjorck H; Irtyuga O; Sergushichev A; Baranov Y; Eriksson P; Kostareva A; Malashicheva A
Conference publication: EUROPEAN JOURNAL OF HUMAN GENETICS. 2018;26:260-261

Candidate gene resequencing in a large BAV/TAA cohort: SMAD6 as an important contributor

Loeys BL; Gillis E; Preuss C; Kumar A; Luyckx I; Cannaerts E; van de Beek G; Wieschendorf B; Alaerts M; Bolar N; Vandeweyer G; Wunnemann F; Gould RA; Zhurayev R; Mohamed SA; Mital S; Mertens L; Eriksson P; Mc Callion A; Van Laer L; Verhagen MA; Vandelaar I; Wessels MW; Messas E; Paderova J; Krebsova A; Kempers M; Salemink S; Duijnhouwer T; Jeunemaitre X; Albuisson J; Andelfinger G; Dietz H; Verstraeten A
Conference publication: EUROPEAN HEART JOURNAL. 2018;39:766-767

New candidate genes for plaque rupture in myocardial infarction

Cederstrom S; Lundman P; Folkersen L; Paulsson-Berne G; Eriksson P; Caidahl K; Gabrielsen A; Jernberg T; Persson J; Tornvall P
Preprint: BIORXIV. 2017

Genome-wide analysis yields new loci associating with aortic valve stenosis

Helgadottir A; Thorleifsson G; Gretarsdottir S; Stefansson OA; Tragante V; Thorolfsdottir RB; Jonsdottir I; Bjornsson T; Steinthorsdottir V; Verweij N; Nielsen JB; Zhou W; Folkersen L; Martinsson A; Heydarpour M; Prakash S; Oskarsson G; Gudbjartsson T; Geirsson A; Olafsson I; Sigurdsson EL; Almgren P; Melander O; Franco-Cereceda A; Hamsten A; Fritsche L; Lin M; Yang B; Hornsby W; Guo D; Brummett CM; Abecasis G; Mathis M; Milewicz D; Body SC; Eriksson P; Willer CJ; Hveem K; Newton-Cheh C; Smith JG; Danielsen R; Thorgeirsson G; Thorsteinsdottir U; Gudbjartsson DF; Holm H; Stefansson K
Meeting abstract: JOURNAL OF VASCULAR SURGERY. 2017;65(6):201S-202S

Finite-Element Analysis-Derived Biomechanical Rupture Risk Index Is Associated With Extracellular Matrix and Structure Organization in the Tunica Media of Abdominal Aortic Aneurysms

Liljeqvist ML; Siika A; Kronqvist M; Eriksson P; Gasser TC; Hultgren R; Roy J
Conference publication: EUROPEAN HEART JOURNAL. 2017;38:1034

PCSK6 is a key protease in the control of smooth muscle cell function in vascular remodelling

Matic L; Rykaczewska U; Rohl S; Razuvaev A; Lengquist M; Sabater-Lleal M; Van Der Laan S; Miller CL; Lindeman JH; Paulsson-Berne G; Quertermous T; Pasterkamp G; Hamsten A; Eriksson P; Hedin U
Conference publication: JOURNAL OF VASCULAR RESEARCH. 2017;54:22

PCSK6 is a Key Protease in the Control of Smooth Muscle Cell Function in Vascular Remodelling

Matic L; Rykaczewska U; Rohl S; Razuvaev A; Lengquist M; Sabater-Lleal M; van der Laan SRW; Miller CL; Rodriquez PQ; Hansson GK; Paulsson-Berne G; Quertermous T; Pasterkamp G; Hamsten A; Eriksson P; Hedin U
Conference publication: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2017;37

Finite Element Analysis-Derived Biomechanical Rupture Risk Index is Associated With Extracellular Matrix and Structure Organization in the Tunica Media of Abdominal Aortic Aneurysms

Liljeqvist ML; Siika A; Kronqvist M; Gasser TC; Eriksson P; Hultgren R; Roy J
Conference publication: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2017;37

Wall Layer-Specific Gene Expression Profile of Coding and Non-Coding Transcripts in Abdominal Aortic Aneurysms

Liljeqvist ML; Hultgren R; Villard C; Kronqvist M; Eriksson P; Roy J
Corrigendum: FRONTIERS IN PHYSIOLOGY. 2017;8:730

Candidate Gene Resequencing in a Large Bicuspid Aortic Valve-Associated Thoracic Aortic Aneurysm Cohort: SMAD6 as an Important Contributor (vol 8, pg 400, 2017)

Gillis E; Kumar AA; Luyckx I; Preuss C; Cannaerts E; van de Beek G; Wieschendorf B; Alaerts M; Bolar N; Vandeweyer G; Meester J; Wunnemann F; Gould RA; Zhurayev R; Zerbino D; Mohamed SA; Mital S; Mertens L; Bjorck HM; Franco-Cereceda A; McCallion AS; Van Laer L; Verhagen JMA; van de Laar IMBH; Wessels MW; Messas E; Goudot G; Nemcikova M; Krebsova A; Kempers M; Salemink S; Dufinhouwer T; Jeunemaitre X; Albuisson J; Eriksson P; Andelfinger G; Dietz HC; Verstraeten A; Loeys BL
Conference publication: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2017;37

The Long Non-Coding RNA H19 Regulates Experimental Abdominal Aortic Aneurysm Development and Progression

Li Y; Jin H; Busch A; Chernogubova E; Backlund A; Olofsson A; Eken S; Sun C; Simon N; Korzunowicz G; Eriksson P; Hultgren R; Roy J; Spin J; Tsao P; Maegdefessel L
Conference publication: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2017;37

MiRNA-210 Enhances Fibrous Cap Stability in Advanced Atherosclerotic Lesions

Eken SM; Jin H; Chernogubova E; Li Y; Simon N; Sun C; Korzunowicz G; Busch A; Backlund A; Osterholm C; Razuvaev A; Renne T; Eckstein HH; Pelisek J; Eriksson P; Diez MG; Perisic LM; Schellinger IN; Raaz U; Leeper NJ; Hansson GK; Paulsson-Berne G; Hedin U; Maegdefessel L
Conference publication: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2017;37

Identification of NCF4 as a Novel Regulator in Arterial Remodeling and Advanced Atherosclerosis

Backlund A; Gertow K; Jin H; Olsson L; Gonzalez-Diez M; Sabater-Lleal M; Strawbridge RJ; Sennblad B; Ohrvik J; Zabaneh D; Shah S; Veglia F; Folkersen L; Gigante B; Leander K; Vikstrom M; Silveira A; Colombo GI; Gabrielsen A; Hedin U; Franco-Cereceda A; Paulsson-Berne G; Nyyssonen K; Tuomainen T-P; Savonen K; Rauramaa R; Smit AJ; Giral P; Mannarino E; van der Laan SW; Pasterkamp G; Hansson GK; Eriksson P; Baldassarre D; Tremoli E; de Faire U; Humphries SE; Hamsten A; Holmdahl R; Maegdefessel L
Meeting abstract: ATHEROSCLEROSIS. 2016;252:E168

INTIMA-MEDIA THICKNESS OF THE DESCENDING AORTA IS INFLUENCED BY AORTIC VALVE DISEASE

Petrini J; Ring M; Eriksson P; Franco-Cereceda A; Caidahl K; Eriksson MJ
Conference publication: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2016;36

Proprotein Convertase Subtilisin/Kexin Type 6 is a Key Protease in the Control of Smooth Muscle Cell Function in Vascular Disease

Hedin U; Perisic L; Rykaczewska U; Razuvaev A; Lengquist M; Sabater-Lleal M; Eriksson I; Rohl S; Kronqvist M; Tseng C-N; Rodriguez P; Folkersen L; Du L; Diez MG; Osterholm C; Roy J; Patrakka J; Paulsson-Berne G; Hansson G; Odeberg J; Hamsten A; Eriksson P
Conference publication: JOURNAL OF THROMBOSIS AND HAEMOSTASIS. 2016;14:64

Novel mechanisms regulating Factor XI plasma levels

Sennblad B; Basu S; Mazur J; Suchon P; Martinez-Perez A; Vlieg VHA; Truong V; Li Y; Gadin JR; Tang W; Grossman V; Handin N; Franco-Cereceda A; Morange P-E; Maegdefessel L; Gagnon F; Soria JM; Eriksson P; Hamsten A; Rosendaal FR; Wild P; Tregouet D; Folsom A; Sabater-Lleal M
Conference publication: CARDIOLOGY. 2016;134(2):205

A Role for Iron in Aortic Valve Stenosis

Laguna-Fernandez A; Carracedo M; Jeanson G; Nagy E; Eriksson P; Caligiuri G; Franco-Cereceda A; Back M
Conference publication: EUROPEAN JOURNAL OF IMMUNOLOGY. 2016;46:440-441

Accelerated atherosclerosis in the context of rheumatoid arthritis

Backlund A; Johansson M; Ria M; Ketelhulth DF; Tsikrika P; Chernogubova E; Jin H; Backlund J; Eriksson P; Maegdefessel L; Holmdahl R; Hansson GK; Hamsten A
Conference publication: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2016;36

Accelerated Atherosclerosis in the Context of Rheumatoid Arthritis

Backlund AB; Johansson M; Ria M; Ketelhulth DF; Tsikrika P; Chernogubova E; Jin H; Backlund J; Eriksson P; Maegdefessel L; Holmdahl R; Hansson GK; Hamsten A
Conference publication: CARDIOVASCULAR RESEARCH. 2016;111:S104

Role of non-coding RNAs in thoracic aortic aneurysm associated with bicuspid aortic valve

Bhattachariya A; Cottrill KA; Du L; Bjorck HM; Maleki S; Franco-Cereceda A; Chan SY; Eriksson P
Conference publication: CARDIOVASCULAR RESEARCH. 2016;111:S106

Role of adenosine-to-inosine RNA editing in human atherosclerosis

Stellos K; Gatsiou A; Stamatelopoulos K; Perisic L; John D; Lunella FF; Eriksson P; Hedin U; Zeiher A; Dimmeler S
Meeting abstract: ATHEROSCLEROSIS. 2015;241(1):E1-E2

ATG16L1 EXPRESSION IN CAROTID ATHEROSCLEROTIC PLAQUES IS ASSOCIATED WITH PLAQUE VULNERABILITY

Magne J; Gustafsson P; Jin H; Maegdefessel L; Hultenby K; Wernerson A; Eriksson P; Franco-Cereceda A; Kovanen PT; Goncalves I; Ehrenborg E
Corrigendum: NATURE COMMUNICATIONS. 2015;6:6506

miR-24 limits aortic vascular inflammation and murine abdominal aneurysm development (vol 5, 5214, 2014)

Maegdefessel L; Spin JM; Raaz U; Eken SM; Toh R; Azuma J; Adam M; Nakagami F; Heymann HM; Chernogubova E; Jin H; Roy J; Hultgren R; Caidahl K; Schrepfer S; Hamsten A; Eriksson P; McConnell MV; Dalman RL; Tsao PS
Conference publication: ARTHRITIS & RHEUMATOLOGY. 2015;67

Auxilin Is a Novel Susceptibility Gene for Congenital Heart Block Modulating Cardiac Function

Meisgen S; Hedlund M; Ambrosi A; Folkersen L; Dzikaite-Ottosson V; Ding B; Strandberg L; Biavati L; Ramskold D; Forsberg D; Bergin L; Ruhrmann S; Hamilton RM; Franco-Cereceda A; Hamsten A; Olsson T; Greene L; Eriksson P; Gemzell-Danielsson K; Salomonsson S; Kuchroo VK; Herlenius E; Kockum I; Sonesson S-E; Wahren-Herlenius M
Conference publication: JOURNAL OF VASCULAR RESEARCH. 2015;52:26

EPIGENETIC CHANGES ASSOCIATED WITH BICUSPID- AND TRICUSPID AORTIC VALVE ANEURYSMS

Bjorck HM; Du L; Paloschi V; Pulignani S; Maleki S; Franco-Cereceda A; Eriksson P
Conference publication: JOURNAL OF VASCULAR RESEARCH. 2015;52:46-47

ANEURYSM DEVELOPMENT IN PATIENTS WITH A BICUSPID AORTIC VALVE IS NOT ASSOCIATED WITH TRANSFORMING GROWTH FACTOR-? ACTIVATION

Paloschi V; Gadin RJ; Bjorck HM; Maleki S; Du L; Franco-cereceda A; Eriksson P
Conference publication: ATHEROSCLEROSIS. 2014;235(2):E20-E21

THE ROLE OF INNATE IMMUNE RECEPTOR NOD2 IN ATHEROSCLEROSIS

Zhang XY; Johansson M; Lundberg A; Levin M; Yuan X; Folkersen L; Eriksson P; Hedin U; Boren J; Hansson GK; Yan ZQ
Conference publication: ATHEROSCLEROSIS. 2014;235(2):E245

EXPRESSION OF ADAMTS-1 IN AAA

Gustafsson T; Vorkapic E; Eriksson P; Wagsater D
Conference publication: ATHEROSCLEROSIS. 2014;235(2):E72

TRIF DEFICIENCY REDUCES THE INFLAMMATORY RESPONSE OF ANGIOTENSIN II-INDUCED ABDOMINAL AORTIC ANEURYSM

Vorkapic E; Lundberg A; Wagsater D; Eriksson P
Conference publication: ATHEROSCLEROSIS. 2014;235(2):E51-E52

INTRA-ADVENTITIAL ADIPOCYTES IN HUMAN AORTA AND RELATIONSHIPS TO METABOLIC RISK FACTORS

Cheung L; Rastas K; Du L; Franco-Cereceda A; Eriksson P; Fisher RM
Meeting abstract: ATHEROSCLEROSIS. 2014;235(2):E222

A FUNCTIONAL GENETIC VARIANT IN THE MICROSOMAL TRIGLYCERIDE TRANSFER PROTEIN IS ASSOCIATED WITH CARDIAC DYSFUNCTION DURING STRESS-INDUCED ISCHEMIA

Ehrenborg E; Mannila MN; Svedlund S; Aminoff A; Eriksson P; Franco-Cereceda A; Boren J; Gan LM
Conference publication: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2014;34

PCSK6 Is Upregulated in Vascular Diseases Characterized by Inflammation and Smooth Muscle Cell Proliferation

Perisic L; Razuvaev A; Osterholm C; Lengquist M; Sabater-Lleal M; Folkersen L; Du L; Diez MG; Hedin E; Ponten F; Paulsson-Berne G; Hamsten A; Odeberg J; Eriksson P; Hedin U
Conference publication: EUROPEAN HEART JOURNAL. 2014;35:301

Diagnostic and prognostic biomarker potential of miR-24 in abdominal aortic aneurysm disease and rupture

Eken SM; Chernogubova E; Spin JM; Raaz U; Jin H; Roy J; Eriksson P; Tsao PS; Maegdefessel L
Conference publication: INTERNIST. 2013;54:10

MicroRNA-24 controls abdominal aortic aneurysm development through regulation of YKL-40

Maegdefessel L; Raaz U; Adam M; Spin J; Eriksson P; Hamsten A; Tsao P
Conference publication: CIRCULATION. 2013;128(22)

Increased Arterial Blood Pressure and Vascular Fibrosis/remodeling in Mice Lacking Salt-inducible Kinase 1 (sik1)

Brion L; Pires N; Igreja B; Pinho MJ; Wagsater D; Wikstrom J; Behrendt M; Hamsten A; Eriksson P; Soares-da-Silva P; Bertorello AM
Conference publication: EUROPEAN HEART JOURNAL. 2013;34:63-64

Array-based profiling reveals biomarker and therapeutic potential for different microRNAs in patients with symptomatic carotid stenosis

Eken SM; Osterholm C; Chernogubova E; Jin H; Razuvajev A; Perisic L; Hedin U; Roy J; Eriksson P; Maegdefessel L
Conference publication: CIRCULATION. 2013;128(22)

Array-Based Profiling Reveals Biomarker and Therapeutic Potential for Different MicroRNAs in Patients With Symptomatic Carotid Stenosis

Eken SM; Osterholm C; Chernogubova E; Perisic L; Roy J; Razuvaev A; Gonzalez-Diez M; Jin H; Hamsten A; Eriksson P; Hedin U; Maegdefessel L
Conference publication: CIRCULATION. 2013;128(22)

MicroRNAs Are Novel Plasma Biomarkers for Diagnosis and Prognosis of Abdominal Aortic Aneurysm Disease

Chernogubova E; Eken SM; Spin JM; Raaz U; Jin H; Roy J; Hamsten A; Eriksson P; Tsao PS; Maegdefessel L
Conference publication: EUROPEAN HEART JOURNAL. 2013;34:1113

MicroRNAs are novel plasma biomarkers for diagnosis and prognosis of abdominal aortic aneurysm disease

Eken SM; Chernogubova E; Jin H; Roy J; Hamsten A; Eriksson P; Tsao PS; Maegdefessel L
Editorial comment: CIRCULATION. 2012;126(15):1815-1817

Quest for Genes and Mechanisms Linking the Human Chromosome 9p21.3 Locus to Cardiovascular Disease

Hamsten A; Eriksson P
Conference publication: VASCULAR PHARMACOLOGY. 2012;56(5-6):377

Association of genetic variants in the NLRP3 region with expression of proximal genes and myocardial infarction

Varghese GP; Folkeresen L; Elmabsout AA; Gabrielsen A; Jansson J-H; Fransen K; Eriksson P; Sirsjo A
Corrigendum: EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY. 2012;41(2):471

Bicuspid aortic valve leaflet morphology in relation to aortic root morphology: a study of 300 patients undergoing open-heart surgery (vol 40, pg e118, 2011)

Jackson V; Petrini J; Caidahl K; Eriksson MJ; Liska J; Eriksson P; Franco-Cereceda A
Conference publication: CIRCULATION. 2012;126(21)

Microrna-24 Regulates Inflammation and Calcification During Abdominal Aortic Aneurysm Development Through Targeting Ykl-40

Maegdefessel L; Raaz U; Toh R; Deng A; Chernogubova E; Eriksson P; Hamsten A; Spin JM; Tsao PS
Conference publication: BRITISH JOURNAL OF SURGERY. 2012;99:11

Genetic determinants of vascular diameter and the risk of abdominal aortic aneurysm

Harrison SC; Zabaneh D; Drenos F; Bown MJ; Gertow K; Baldassare D; Asselbergs FW; Jones GT; Baas AF; Kumari M; Fowkes FG; Eriksson P; Hamsten A; Humphries SE
Conference publication: ATHEROSCLEROSIS SUPPLEMENTS. 2011;12(1):62

SERINE PROTEASE INHIBITOR A3 INFLUENCES AORTIC ANEURYSM FORMATION BUT NOT ATHEROSCLEROSIS

Wagsater D; Johansson D; Zhou X; Eriksson P
Corrigendum: JOURNAL OF INTERNAL MEDICINE. 2011;269(4):468

Low plasma adiponectin concentration is associated with myocardial infarction in young individuals (vol 268, pg 194, 2010)

Persson J; Lindberg K; Gustafsson TP; Eriksson P; Paulsson-Berne G; Lundman P
Conference publication: DIABETOLOGIA. 2011;54:S15

Expression of brown adipose tissue markers in different human adipose tissue depots

Cheung L; Chmielewska J; Petrovic N; Eriksson P; Nedergaard J; Fisher R
Meeting abstract: ATHEROSCLEROSIS SUPPLEMENTS. 2010;11(2):178

ECHOCARDIOGRAPHIC VISUAL VERSUS COMPUTERIZED EVALUATION OF THE DEGREE OF AORTIC VALVE CALCIFICATION IN PATIENTS WITH AORTIC VALVE AND ROOT PATHOLOGY

Yousry M; Eriksson MJ; Rickenlund A; Petrini J; Gustavsson T; Eriksson P; Hamsten A; Franco-Cereceda A; Liska J; Caidahl K
Conference publication: JOURNAL OF THROMBOSIS AND HAEMOSTASIS. 2010;8:53

Allele-specific transcription of the plasminogen activator inhibitor (PAI-1) gene in human astrocytes under in vivo conditions

Hultman K; Tjarnlund-Wolf A; Odeberg J; Eriksson P; Jern C
Conference publication: CIRCULATION. 2009;120(18):S385

Vascular Assessment - New Application for Velocity Vector Imaging

Petrini J; Eriksson MJ; Yousry M; Rickenlund A; Eriksson P; Hamsten A; Liska J; Franco-Cereceda A; Caidahl K
Conference publication: ATHEROSCLEROSIS SUPPLEMENTS. 2009;10(2)

LYSYL-OXIDASE-DEPENDED EXTRACELLULAR MATURATION OF COLLAGEN IS REDUCED IN HYPERINFLAMED ATHEROSCLEROTIC PLAQUES OF APOE-/- MICE

Ovchinnikova O; Robertson A-K; Wagsater D; Folco E; Hyry M; Myllyharju J; Eriksson P; Gavrisheva N; Shlyakhto E; Libby P; Hansson G
Conference publication: ATHEROSCLEROSIS SUPPLEMENTS. 2009;10(2)

LOW ADIPONECTIN CONCENTRATION IS A RISK FACTOR FOR MYOCARDIAL INFARCTION AND LEVELS ARE INFLUENCED BY GENETIC VARIANTS

Persson J; Eriksson P; Gustafsson T; Berne GP; Lundman P
Letter: NATURE GENETICS. 2008;40(12):1387-1388

Lack of support for association between common variation in TNFSF4 and myocardial infarction in a German population Reply

Wang X; Ria M; Eriksson P; de Faire U; Hamsten A; Paigen B
Letter: JOURNAL OF INTERNAL MEDICINE. 2008;264(6):613-617

Vaccination, a human model of inflammation, activates systemic inflammation but does not trigger proinflammatory gene expression in adipose tissue

Ekstrom M; Eriksson P; Tornvall P
Meeting abstract: ATHEROSCLEROSIS SUPPLEMENTS. 2008;9(1):60

PDGF-C AND PDGF-D IN ATHEROSCLEROSIS

Wagsater D; Bjorck H; Zhu C; Eriksson P
Conference publication: FASEB JOURNAL. 2007;21(5):A575

A single bout of exercise activates matrix metalloproteinase in human skeletal muscle

Rullman E; Rundqvist H; Wagsater D; Fischer H; Eriksson P; Sundberg C-J; Jansson E; Gustafsson T
Published conference paper: ANNALS OF THE NEW YORK ACADEMY OF SCIENCES. 2006;1085:133-138

The intraluminal thrombus as a source of proteolytic activity

Swedenborg J; Eriksson P
Conference publication: DIABETOLOGIA. 2006;49:436

Adipose tissue is infiltrated with macrophages around dead fat cells in subjects with high liver fat content, independent of obesity

Westerbacka J; Kolak M; Wagsater D; Rissanen A; Hakkinen A-M; Eriksson P; Fisher RM; Yki-Jarvinen H
Conference publication: ATHEROSCLEROSIS SUPPLEMENTS. 2006;7(3):158

Functional polymorphisms in fibrinolysis and proteolysis genes: Influences of gene-environment interactions

Eriksson P
Meeting abstract: ATHEROSCLEROSIS SUPPLEMENTS. 2006;7(3):406

Invariant NKT cells present in human atherosclerotic lesions

Agardh HE; Eriksson P; Tupin E; Kazi M; Hedin U; Olsson A; Hansson GK; Swedenborg J; Paulsson-Berne G
Meeting abstract: ATHEROSCLEROSIS SUPPLEMENTS. 2006;7(3):145

A new OX40L promoter haplotype showing association with coronary artery disease in the PROCARDIS trio family and SCARF cohorts

Ria M; Olsson PG; Bengtsson O; Eriksson P; Hamsten A; Lagercrantz J
Meeting abstract: ATHEROSCLEROSIS SUPPLEMENTS. 2006;7(3):316

Matrix metalloproteinase-1 gene haplotype influences risk of myocardial infarction

Pearce E; Tregouet D; Samnergard A; Morgan A; Cox C; Hamsten A; Eriksson P; Ye S
Corrigendum: EUROPEAN HEART JOURNAL. 2005;26(9):942

'Association of hypo-responsive toll-like receptor 4 variants with risk of myocardial infarction' (vol 25, pg 1447, 2004)

Edfeldt K; Bennet AM; Eriksson P; Frostegård J; Wiman B; Hamsten A; Hansson GK; de Faire U; Yan ZQ
Meeting abstract: ATHEROSCLEROSIS SUPPLEMENTS. 2005;6(1):92

The fibrinogen gene loci revisited

Hamsten A; Mannila MN; Eriksson P; Silveira A
Letter: EUROPEAN JOURNAL OF CLINICAL INVESTIGATION. 2005;35(2):154-155

Effects of free fatty acids and a triglyceride-rich fat emulsion on endothelial nitric oxide synthase

Halle M; Eriksson P; Tornvall P
Conference publication: ARTHRITIS & RHEUMATOLOGY. 2005;52(9):S237-S238

The MHC2 transactivator gene polymorphism show association with susceptibility to rheumatoid arthritis

Padyukov L; Eriksson P; Börjesson O; Piehl F; Olsson T; Alfredsson L; Klareskog L
Review: ACTA CHIRURGICA BELGICA. 2004;104(6):606-608

Influence of the intraluminal thrombus in abdominal aortic aneurysms

Swedenborg J; Kazi M; Eriksson R; Hedin U
Conference publication: STROKE. 2004;35(6):E291

Plasminogen activator inhibitor polymorphism and risk of stroke. Replicated findings in two nested case-control studies

Wiklund PG; Nilsson L; Johansson L; Stegmayr B; Asplund K; Hamsten A; Holmberg D; Ardnor S; Eriksson P
Published conference paper: BRITISH JOURNAL OF SURGERY. 2003;91(1):86-89

Genetic approach to the role of cysteine proteases in the expansion of abdominal aortic aneurysms

Eriksson P; Jones KG; Brown LC; Greenhalgh RM; Hamsten A; Powell JT
Published conference paper: JOURNAL OF VASCULAR SURGERY. 2003;38(6):1283-1292

Influence of intraluminal thrombus on structural and cellular composition of abdominal aortic aneurysm wall

Kazi M; Thyberg J; Religa P; Roy J; Eriksson P; Hedin U; Swedenborg J
Meeting abstract: EUROPEAN HEART JOURNAL. 2003;24:156

Expression of Toll-like receptors in human atherosclerotic lesions and the relevance to myocardial infarction

Edfeldt K; Bennet AM; Eriksson P; Hamsten A; Hansson GK; DeFaire U; Yan ZQ
Conference publication: ATHEROSCLEROSIS SUPPLEMENTS. 2003;4(2):320-321

Influences of matrix metalloproteinase-3 gene variation on extent of coronary atherosclerosis and risk of myocardial infarction

Beyzade S; Zhang S; Wong YK; Day I; Eriksson P; Ye S
Conference publication: CIRCULATION. 2003;108(17):634

Genetic evidence for a role of plasminogen activator inhibitor-1 but not matrix metalloproteinase-2,-9 or-12 in the expansion of small aortic aneurysms

Powell JT; Jormsjo-Pettersson S; Brady AR; Jones KG; Ye S; Deguchi H; Hamsten A; Eriksson P
Conference publication: ATHEROSCLEROSIS SUPPLEMENTS. 2003;4(2):323

Expression of ADAMTS-1 in apo E null mouse

Björk H; Sirsjö A; Eriksson P; Hamsten A
Editorial comment: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2003;23(1):6-7

Thrombospondins and premature coronary artery disease - Time to go beyond genotype-phenotype association studies

Hamsten A
Meeting abstract: ATHEROSCLEROSIS SUPPLEMENTS. 2003;4(2):254

Influence of intraluminal thrombus on cellular and structural features of the aneurysm wall

Kazi M; Thyberg J; Religa P; Roy J; Eriksson R; Ulf H; Swedenborg J
Meeting abstract: ATHEROSCLEROSIS SUPPLEMENTS. 2003;4(2):323

Human evidence that the cystatin C gene is implicated in focal progression of coronary artery disease

Eriksson P; Deguchi H; Samnegard A; Lundman P; Boquist S; Tornvall P; Ericsson CG; Bergstrand L; Hansson LO; Hamsten A
Meeting abstract: ATHEROSCLEROSIS SUPPLEMENTS. 2003;4(2):48-49

Genetic and structural evaluation of fatty acid transport protein-4 (FATP4) in relation to markers of the insulin resistance syndrome

Gertow K; Bellanda M; Sunnerhagen M; Eriksson P; Boquist S; Hamsten A; Fisher R
Meeting abstract: ATHEROSCLEROSIS SUPPLEMENTS. 2003;4(2):31

Characterization of the human homologue to the Ath1 atherosclerosis susceptibility locus in mice

Ria M; Eriksson P; Forsman-Semb K; Olsson PG; Hamsten A; Lagercrantz J
Letter: DIABETOLOGIA. 2001;44(5):654-655

Tumour necrosis factor-α (TNF-α) polymorphisms-857C/A and -863C/A are associated with TNF-α secretion from human adipose tissue

Skoog T; Eriksson P; Hoffstedt J; Rydén M; Hamsten A; Arner P
Conference publication: EUROPEAN HEART JOURNAL. 2001;22:70

Increased expression of matrix metalloproteinase 9 in atherosclerotic plaques from patients with acute coronary syndromes

Valen G; Eriksson P; Hansson GK; Herzfeld I; Chen F
Published conference paper: ANNALS OF THE NEW YORK ACADEMY OF SCIENCES. 2000;902:27-37

Genetic diversity in the matrix metalloproteinase family -: Effects on function and disease progression

Henney AM; Ye S; Zhang BP; Jormsjö S; Whatling C; Eriksson P; Hamsten A
Meeting abstract: ATHEROSCLEROSIS. 1999;144:127

Very low density lipoprotein and free fatty acids stimulate nuclear factor-κB activation in endothelial cells

Dichtl W; Nilsson L; Goncalves MI; Ares MPS; Banfi C; Calara F; Hamsten A; Eriksson P; Nilsson J
Meeting abstract: ATHEROSCLEROSIS. 1999;144:112-113

VLDL activation of plasminogen activator inhibitor-1 (PAI-1) expression:: Involvement of the VLDL receptor

Nilsson L; Gåfvels M; Musakka L; Ensler K; Strickland DK; Angelin B; Hamsten A; Eriksson P
Meeting abstract: ATHEROSCLEROSIS. 1999;144:121

A common polymorphism in the promoter region of TNF-alpha gene determining the serum TNF-alpha concentration

Skoog T; van't Hooft FM; Kallin B; Nilsson J; Eriksson P; Hamsten A
Corrigendum: DIABETES. 1998;47(9):1532

Leptin secretion from subcutaneous and visceral adipose tissue in women (vol 47, pg 913, 1998)

Van Harmelen V; Reynisdottir S; Eriksson P; Thörne A; Hoffstedt J; Lönnqvist F; Arner P
Conference publication: ATHEROSCLEROSIS. 1998;138:S3

A common functional polymorphism in the promoter region of the MTP gene influences the plasma LDL level

Karpe F; Lundahl B; Ehrenborg E; Eriksson P; Hamsten A
Conference publication: CIRCULATION. 1998;98(17):524

A C→A polymorphism at position 6390 within intron 6 of the thrombopoietin gene is associated with myocardial infarction in young Swedish men

Webb KE; Hamsten A; Eriksson P; Humphries SE; Martin JF
Review: INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY. 1997;29(5):731-742

The role of chromatin in transcriptional regulation

Li Q; Wrange O; Eriksson P
Review: BEST PRACTICE & RESEARCH CLINICAL HAEMATOLOGY. 1995;8(2):345-363

FIBRINOLYSIS AND ATHEROSCLEROSIS

HAMSTEN A; ERIKSSON P
Conference publication: JOURNAL OF CELLULAR BIOCHEMISTRY. 1994;:337

FUNCTIONAL-STUDIES OF AN INS/DEL POLYMORPHISM IN THE PAI-1 PROMOTER REGION WHICH IS ASSOCIATED WITH MYOCARDIAL-INFARCTION AT A YOUNG AGE

ERIKSSON P; KALLIN B; VANTHOOFT F; HAMSTEN A
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Grants

Aortic valve disease and associated thoracic aortic aneurysm

Swedish Research Council

1 January 2021 - 31 December 2023
THORACIC AORTIC ANEURYSM PATHOLOGY

Swedish Heart-Lung Foundation

1 January 2019 - 31 December 2021
Molecular aspects of thoracic aortic aneurysm pathology

Swedish Research Council

1 January 2017 - 31 December 2020
MECHANISMS OF FORMATION, GROWTH AND RUPTURE OF AORTIC ANEURYSMS

Swedish Research Council

1 January 2012 - 31 December 2016
MIBAVA-Mechanistic Interrogation of Bicuspid Aortic Valve associated Aortopathy

Fondation Leducq

1 January 2012
MECHANISMS OF FORMATION, GROWTH AND RUPTURE OF AORTIC ANEURYSMS

Swedish Research Council

1 January 2009 - 31 December 2011

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