Per Arvidsson

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Articles

Journal article: RSC MEDICINAL CHEMISTRY. 2025;16(8):3393-3415
Navigating the complexities of drug development for metallo-β-lactamase inhibitors
Reddy N; Balieiro AM; Silva JRA; Gouws CA; Mutshembele A; Arvidsson PI; Kruger HG; Govender T; Naicker T
Journal article: RSC ADVANCES. 2025;15(29):23427-23440
Development and in vitro evaluation of 1,4,7-triazacyclononane-coupled β-lactams against metallo-β-lactamase producing bacteria
Shungube M; Reddy N; Ghazi T; Govender KB; Singh R; Kajee A; Chuturgoon A; Kruger HG; Arvidsson PI; Tiwari D; Govender T; Naicker T
Article: CHEMISTRYOPEN. 2025;14(7):e202400432
Facile Synthesis of Oxazolidinones as Potential Antibacterial Agents
Els SP; Govender KB; Sokhela MK; Bhatt N; Reddy N; Kruger HG; Arvidsson PI; Gunosewoyo H; Govender T; Naicker T
Journal article: JOURNAL OF MEDICINAL CHEMISTRY. 2025;68(4):4056-4058
Sulfilimines: An Underexplored Bioisostere for Drug Design?
Arvidsson PI
Article: ACS OMEGA. 2024;9(35):37155-37162
The Oxidation of Electron-Rich Arenes Using a H₂O₂-Proline System
Chetty LC; Kruger HG; Arvidsson PI; Maguire GEM; Govender T; Naicker T
Article: RSC ADVANCES. 2024;14(12):7992-7998
Investigating the efficacy of green solvents and solvent-free conditions in hydrogen-bonding mediated organocatalyzed model reactions
Chetty LC; Kruger HG; Arvidsson PI; Naicker T; Govender T
Article: TETRAHEDRON LETTERS. 2023;124:154583
N-Arylation of primary and tertiary sulfonimidamides (SIAs) with benzyne precursors under transition metal-free conditions
Ambala S; Govender KB; Rajbongshi KK; Govender T; Kruger HG; Naicker T; Arvidsson PI
Article: RSC ADVANCES. 2023;13(28):18991-19001
Synthesis and biological evaluation of novel blactam-metallo β-lactamase inhibitors
Shungube M; Hlophe AK; Girdhari L; Sabe VT; Peters BB; Reddy N; Omolabi KF; Chetty L; Arumugam T; Chuturgoon A; Kruger HG; Arvidsson PI; Qin H-L; Naicker T; Govender T
Article: ANTIBIOTICS-BASEL. 2023;12(4):633
Neutralizing Carbapenem Resistance by Co-Administering Meropenem with Novel fi-Lactam-Metallo- β-Lactamase Inhibitors
Reddy N; Girdhari L; Shungube M; Gouws AC; Peters BK; Rajbongshi KK; Baijnath S; Mdanda S; Ntombela T; Arumugam T; Bester LA; Singh SD; Chuturgoon A; Arvidsson PI; Maguire GEM; Kruger HG; Govender T; Naicker T
Article: ACS INFECTIOUS DISEASES. 2023;9(3):486-496
In Vitro and In Vivo Development of a β-Lactam-Metallo-β- Lactamase Inhibitor: Targeting Carbapenem-Resistant Enterobacterales
Peters BK; Reddy N; Shungube M; Girdhari L; Baijnath S; Mdanda S; Chetty L; Ntombela T; Arumugam T; Bester LA; Singh SD; Chuturgoon A; Arvidsson PI; Maguire GEM; Kruger HG; Naicker T; Govender T
Article: SYNTHESIS-STUTTGART. 2022;54(21):4827-4833
Organic Base-Mediated Carboxylation of (Hetero)aromatic Compounds Using Supercritical Carbon Dioxide (scCO₂)
Chetty LC; Kruger HG; Arvidsson PI; Naicker T; Govender T
Article: NATURE CANCER. 2022;3(2):156-172
Pharmacological targeting of MTHFD2 suppresses acute myeloid leukemia by inducing thymidine depletion and replication stress
Bonagas N; Gustafsson NMS; Henriksson M; Marttila P; Gustafsson R; Wiita E; Borhade S; Green AC; Vallin KSA; Sarno A; Svensson R; Gokturk C; Pham T; Jemth A-S; Loseva O; Cookson V; Kiweler N; Sandberg L; Rasti A; Unterlass JE; Haraldsson M; Andersson Y; Scaletti ER; Bengtsson C; Paulin CBJ; Sanjiv K; Abdurakhmanov E; Pudelko L; Kunz B; Desroses M; Iliev P; Farnegardh K; Kramer A; Garg N; Michel M; Haggblad S; Jarvius M; Kalderen C; Jensen AB; Almlof I; Karsten S; Zhang SM; Haggblad M; Eriksson A; Liu J; Glinghammar B; Nekhotiaeva N; Klingegard F; Koolmeister T; Martens U; Llona-Minguez S; Moulson R; Nordstrom H; Parrow V; Dahllund L; Sjoberg B; Vargas IL; Vo DD; Wannberg J; Knapp S; Krokan HE; Arvidsson PI; Scobie M; Meiser J; Stenmark P; Berglund UW; Homan EJ; Helleday T
Journal article: ACS OMEGA. 2020;5(37):24154
Improved Synthesis and Isolation of Bedaquiline (vol 5, pg 3607, 2020)
Lubanyana H; Arvidsson PI; Govender T; Kruger HG; Naicker T
Journal article: EUROPEAN JOURNAL OF ORGANIC CHEMISTRY. 2020;2020(25):3734
Front Cover: Solid Phase Synthesis of Sulfonimidamide Pseudopeptides and Library Generation (Eur. J. Org. Chem. 25/2020)
Chinthakindi PK; Benediktsdottir A; Arvidsson PI; Chen Y; Sandström A
Article: EUROPEAN JOURNAL OF ORGANIC CHEMISTRY. 2020;2020(25):3796-3807
Solid Phase Synthesis of Sulfonimidamide Pseudopeptides and Library Generation
Chinthakindi PK; Benediktsdottir A; Arvidsson PI; Chen Y; Sandstrom A
Article: NEUROTHERAPEUTICS. 2020;17(3):1142-1152
Characterization of More Selective Central Nervous System Nrf2-Activating Novel Vinyl Sulfoximine Compounds Compared to Dimethyl Fumarate
Carlstrom KE; Chinthakindi PK; Espinosa B; Al Nimer F; Arner ESJ; Arvidsson PI; Piehl F; Johansson K
Article: REDOX BIOLOGY. 2020;32:101491
Comprehensive chemical proteomics for target deconvolution of the redox active drug auranofin
Saei AA; Gullberg H; Sabatier P; Beusch CM; Johansson K; Lundgren B; Arvidsson PI; Arner ESJ; Zubarev RA
Article: SYNTHESIS-STUTTGART. 2020;52(8):1279-1286
Microwave-Accelerated N -Acylation of Sulfoximines with Aldehydes under Catalyst-Free Conditions
Rajbongshi KK; Ambala S; Govender T; Kruger HG; Arvidsson PI; Naicker T
Article: ACS OMEGA. 2020;5(7):3607-3611
Improved Synthesis and Isolation of Bedaquiline
Lubanyana H; Arvidsson PI; Govender T; Kruger HG; Naicker T
Article: ACS MEDICINAL CHEMISTRY LETTERS. 2019;10(10):1457-1461
N-Trifluoromethylthiolated Sulfonimidamides and Sulfoximines: Anti-microbial, Anti-mycobacterial, and Cytotoxic Activity
Thota N; Makam P; Rajbongshi KK; Nagiah S; Abdul NS; Chuturgoon AA; Kaushik A; Lamichhane G; Somboro AM; Kruger HG; Govender T; Naicker T; Arvidsson PI
Article: EUROPEAN JOURNAL OF ORGANIC CHEMISTRY. 2019;2019(5):1045-1057
Synthesis of Sulfonimidamide-Based Amino Acid Building Blocks with Orthogonal Protecting Groups
Chinthakindi PK; Benediktsdottir A; Ibrahim A; Wared A; Aurell C-J; Pettersen A; Zamaratski E; Arvidsson PI; Chen Y; Sandstrom A
Article: RSC ADVANCES. 2018;8(65):37503-37507
Synthesis of novel 1,2,4-thiadiazinane 1,1-dioxides via three component SuFEx type reaction
Khumalo MF; Akpan ED; Chinthakindi PK; Brasil EM; Rajbongshi KK; Makatini MM; Govender T; Kruger HG; Naicker T; Arvidsson PI
Article: XENOBIOTICA. 2018;48(9):938-944
The downfall of TBA-354-a possible explanation for its neurotoxicity via mass spectrometric imaging
Ntshangase S; Shobo A; Kruger HG; Asperger A; Niemeyer D; Arvidsson PI; Govender T; Baijnath S
Article: RSC ADVANCES. 2018;8(1):190-193
An unexpected re-arrangement of the antibiotic carbapenem core to new 1,4-diazepin-5-one scaffolds
Peters BK; Razuwika R; Samipillai M; Arvidsson PI; Kruger HG; Govender T; Naicker T
Article: INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS. 2018;51(1):77-81
Clofazimine protects against Mycobacterium tuberculosis dissemination in the central nervous system following aerosol challenge in a murine model
Baijnath S; Moodley C; Ngcobo B; Singh SD; Kruger HG; Arvidsson PI; Naicker T; Pym A; Govender T
Article: BIOMEDICAL CHROMATOGRAPHY. 2017;31(12)
Lansoprazole-sulfide, pharmacokinetics of this promising anti-tuberculous agent
Mdanda S; Baijnath S; Shobo A; Singh SD; Maguire GEM; Kruger HG; Arvidsson PI; Naicker T; Govender T
Article: FUTURE SCIENCE OA. 2017;3(2):FSO183
On the bridge over the translational valley of death: interview with Per I Arvidsson
Arvidsson PI
Journal article: FUTURE SCIENCE OA. 2017;3(2):FSO176
Institutional profile: the national Swedish academic drug discovery & development platform at SciLifeLab
Arvidsson PI; Sandberg K; Sakariassen KS
Journal article: ANGEWANDTE CHEMIE-INTERNATIONAL EDITION. 2017;129(15):4160-4170
Sulfonimidamide in medizinischer Chemie und Agrochemie
Chinthakindi PK; Naicker T; Thota N; Govender T; Kruger HG; Arvidsson PI
Article: ORGANIC LETTERS. 2017;19(3):480-483
A Synthesis of "Dual Warhead" β-Aryl Ethenesulfonyl Fluorides and One-Pot Reaction to β-Sultams
Chinthakindi PK; Govender KB; Kurnar AS; Kruger HG; Govender T; Naicker T; Arvidsson PI
Journal article: CHEMINFORM. 2016;47(43):no
ChemInform Abstract: Enantioselective Organocatalyzed Transformations of β‐Ketoesters
Govender T; Arvidsson PI; Maguire GEM; Kruger HG; Naicker T
Journal article: CHEMINFORM. 2016;47(42):no
ChemInform Abstract: An Efficient Protecting‐Group‐Free Synthesis of Vinylic Sulfoximines via Horner—Wadsworth—Emmons Reaction.
Chinthakindi PK; Nandi GC; Govender T; Kruger HG; Naicker T; Arvidsson PI
Article: JOURNAL OF MOLECULAR HISTOLOGY. 2016;47(4):429-435
Neuroprotective potential of Linezolid: a quantitative and distribution study via mass spectrometry
Baijnath S; Shobo A; Bester LA; Singh SD; Kruger G; Arvidsson PI; Naicker T; Govender T
Article: SYNLETT. 2016;27(11):1685-1688
A Facile Synthesis of NODASA-Functionalized Peptide
Dutta J; Chinthakindi PK; Arvidsson PI; de la Torre BG; Kruger HG; Govender T; Naicker T; Albericio F
Journal article: CHEMINFORM. 2016;47(31):no
ChemInform Abstract: On‐Water Synthesis of Biaryl Sulfonyl Fluorides.
Chinthakindi PK; Kruger HG; Govender T; Naicker T; Arvidsson PI
Article: SYNLETT. 2016;27(9):1423-1427
An Efficient Protecting-Group-Free Synthesis of Vinylic Sulfoximines via Horner-Wadsworth-Emmons Reaction
Chinthakindi PK; Nandi GC; Govender T; Kruger HG; Naicker T; Arvidsson PI
Article: JOURNAL OF ORGANIC CHEMISTRY. 2016;81(6):2618-2623
On-Water Synthesis of Biaryl Sulfonyl Fluorides
Chinthakindi PK; Kruger HG; Govender T; Naicker T; Arvidsson PI
Article: ARKIVOC. 2016;:134-144
Stereoselective synthesis towards unnatural proline-based amino acids
Makhathini SS; Das SK; Singh T; Arvidsson PI; Kruger HG; Gunosewoyo H; Govender T; Naicker T
Article: SOUTH AFRICAN JOURNAL OF CHEMISTRY-SUID-AFRIKAANSE TYDSKRIF VIR CHEMIE. 2016;69:72-78
Organocatalyzed Mannich Reactions on Minocycline: Towards Novel Tetracycline Antibiotics
Chiwunze TE; Azumah R; Ramtahal M; Somboro AM; Arvidsson PI; Kruger HG; Govender T; Naicker T
Journal article: CHEMINFORM. 2016;47(1):no
ChemInform Abstract: Towards a Stereoselective Synthesis of α,α‐Disubstituted Proline Analogues.
Das SK; Bhatt N; Mujahid M; Arvidsson PI; Kruger HG; Naicker T; Govender T
Journal article: CHEMINFORM. 2015;46(48):no
ChemInform Abstract: Pd‐Catalyzed C—N Coupling of Vinylbromides and Sulfonimidamides: A Facile Synthesis of N′‐Vinylsulfonimidamides.
Nandi GC; Kota SR; Wakchaure PB; Chinthakindi PK; Govender T; Kruger HG; Naicker T; Arvidsson PI
Article: ORGANIC & BIOMOLECULAR CHEMISTRY. 2015;13(39):9993-10006
The effect of N-methylation of amino acids (Ac-X-OMe) on solubility and conformation: a DFT study
Rauf SMA; Arvidsson PI; Albericio F; Govender T; Maguire GEM; Kruger HG; Honarparvar B
Article: TETRAHEDRON LETTERS. 2015;56(37):5172-5174
Towards a stereoselective synthesis of α,α-disubstituted proline analogues
Das SK; Bhatt N; Mujahid M; Arvidsson PI; Kruger HG; Naicker T; Govender T
Journal article: CHEMINFORM. 2015;46(36):no
ChemInform Abstract: Cu(OAc)2‐Catalyzed Oxidative Dual C‐H/N‐H Activation of Terminal Alkynes and N‐Deprotected Sulfonimidamides: An Easy Access to N‐Alkynylated Sulfonimidamides.
Nandi GC; Kota SR; Naicker T; Govender T; Kruger HG; Arvidsson PI
Journal article: CHEMINFORM. 2015;46(23):no
ChemInform Abstract: Applied Enantioselective Aminocatalysis: α‐Heteroatom Functionalization Reactions on the Carbapenem (β‐Lactam Antibiotic) Core.
Cele ZED; Arvidsson PI; Kruger HG; Govender T; Naicker T
Article: EUROPEAN JOURNAL OF ORGANIC CHEMISTRY. 2015;2015(13):2861-2867
Cu(OAc)₂-Catalysed Oxidative Dual C-H/N-H Activation of Terminal Alkynes and N-Deprotected Sulfonimidamides: An Easy Access to N-Alkynylated Sulfonimidamides
Nandi GC; Kota SR; Naicker T; Govender T; Kruger HG; Arvidsson PI
Journal article: CHEMINFORM. 2015;46(20):no
ChemInform Abstract: Synthesis of Vinyl‐ and Aryl‐Acyl Sulfonimidamides Through Pd‐Catalyzed Carbonylation Using Mo(CO)6 as ex situ CO Source.
Wakchaure PB; Borhade SR; Sandstroem A; Arvidsson PI
Journal article: JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY. 2015;70(5):1594-1596
NOTA: a potent metallo-β-lactamase inhibitor
Somboro AM; Tiwari D; Bester LA; Parboosing R; Chonco L; Kruger HG; Arvidsson PI; Govender T; Naicker T; Essack SY
Article: CHEMMEDCHEM. 2015;10(3):455-460
Preclinical Characterization of Acyl Sulfonimidamides: Potential Carboxylic Acid Bioisosteres with Tunable Properties
Borhade SR; Svensson R; Brandt P; Artursson P; Arvidsson PI; Sandstroem A
Journal article: CHEMINFORM. 2015;46(5):no
ChemInform Abstract: Organocatalytic Mannich Reactions on a Carbapenem Core — Synthesis of Mannich Bases and Bicyclic Diazanonanes.
Cele ZED; Pawar SA; Naicker T; Maguire GEM; Arvidsson PI; Kruger HG; Govender T
Article: RSC ADVANCES. 2015;5(76):62084-62090
Pd-catalyzed C-N coupling of vinylbromides and sulfonimidamides: a facile synthesis of N′-vinylsulfonimidamides
Nandi GC; Kota SR; Wakchaure PB; Chinthakindi PK; Govender T; Kruger HG; Naicker T; Arvidsson PI
Article: EUROPEAN JOURNAL OF ORGANIC CHEMISTRY. 2015;2015(3):638-646
Applied Enantioselective Aminocatalysis: α-Heteroatom Functionalization Reactions on the Carbapenem (β-Lactam Antibiotic) Core
Cele ZED; Arvidsson PI; Kruger HG; Govender T; Naicker T
Article: EUROPEAN JOURNAL OF ORGANIC CHEMISTRY. 2015;2015(1):213-219
Synthesis of Vinyl- and Aryl-Acyl Sulfonimidamides Through Pd-Catalyzed Carbonylation Using Mo(CO)₆ as ex situ CO Source
Wakchaure PB; Borhade SR; Sandstroem A; Arvidsson PI
Journal article: CHEMINFORM. 2015;46(4):no
ChemInform Abstract: L‐Proline Organocatalyzed Michael Synthesis of Monobactam and Carbapenem β‐Lactam Cores.
Khanyase S; Naicker T; Maguire GEM; Kruger HG; Arvidsson PI; Govender T
Journal article: CHEMINFORM. 2015;46(3):no
ChemInform Abstract: Cu(OAc)2 Promoted Chan—Evans—Lam C—N Cross Coupling Reactions on the N‐ and N′‐Nitrogen Atoms of Sulfonimidamides with Aryl Boronic Acids.
Nandi GC; Kota SR; Govender T; Kruger HG; Arvidsson PI
Article: FEBS JOURNAL. 2015;282(1):65-73
Combining an amyloid-beta (Aβ) cleaving enzyme inhibitor with a γ-secretase modulator results in an additive reduction of Aβ production
Stromberg K; Eketjall S; Georgievska B; Tunblad K; Eliason K; Olsson F; Radesater A-C; Klintenberg R; Arvidsson PI; von Berg S; Falting J; Cowburn RF; Dabrowski M
Article: TETRAHEDRON. 2014;70(35):5428-5433
Cu(OAc)₂ promoted Chan-Evans-Lam C-N cross coupling reactions on the N- and N'-nitrogen atoms of sulfonimidamides with aryl boronic acids
Nandi GC; Kota SR; Govender T; Kruger HG; Arvidsson PI
Article: TETRAHEDRON ASYMMETRY. 2014;25(13-14):969-973
L-Proline organocatalyzed Michael synthesis of monobactam and carbapenem β-lactam cores
Khanyase S; Naicker T; Maguire GEM; Kruger HG; Arvidsson PI; Govender T
Article: ORGANIC & BIOMOLECULAR CHEMISTRY. 2014;12(25):4479-4490
Proline N-oxides: modulators of the 3D conformation of linear peptides through "NO-turns"
Farahani MD; Honarparvar B; Albericio F; Maguire GEM; Govender T; Arvidsson PI; Kruger HG
Journal article: CHEMINFORM. 2014;45(17):no
ChemInform Abstract: Organocatalyzed Stereospecific C—C Bond Formation of β‐Lactams.
Pawar SA; Alapour S; Khanyase S; Cele ZED; Chitti S; Kruger HG; Govender T; Arvidsson PI
Article: EUROPEAN JOURNAL OF ORGANIC CHEMISTRY. 2014;2014(11):2253-2260
Organocatalytic Mannich Reactions on a Carbapenem Core-Synthesis of Mannich Bases and Bicyclic Diazanonanes
Cele ZED; Pawar SA; Naicker T; Maguire GEM; Arvidsson PI; Kruger HG; Govender T
Article: ORGANIC & BIOMOLECULAR CHEMISTRY. 2013;11(48):8294-8297
Organocatalyzed stereospecific C-C bond formation of β-lactams
Pawar SA; Alapour S; Khanyase S; Cele ZED; Chitti S; Kruger HG; Govender T; Arvidsson PI
Journal article: CHEMINFORM. 2013;44(32):no
ChemInform Abstract: Synthesis of Novel Aryl and Heteroaryl Acyl Sulfonimidamides via Pd‐Catalyzed Carbonylation Using a Nongaseous Precursor.
Borhade SR; Sandstroem A; Arvidsson PI
Journal article: CHEMINFORM. 2013;44(31):no
ChemInform Abstract: Organocatalytic Asymmetric Cross‐Aldol Reaction of 2‐Chloroethoxy Acetaldehyde: Diversity‐Oriented Synthesis of Chiral Substituted 1,4‐Dioxanes and Morpholines.
Sawant RT; Stevenson J; Odell LR; Arvidsson PI
Article: JOURNAL OF NEUROCHEMISTRY. 2013;125(3):446-456
AZD1080, a novel GSK3 inhibitor, rescues synaptic plasticity deficits in rodent brain and exhibits peripheral target engagement in humans
Georgievska B; Sandin J; Doherty J; Mortberg A; Neelissen J; Andersson A; Gruber S; Nilsson Y; Schott P; Arvidsson PI; Hellberg S; Osswald G; Berg S; Falting J; Bhat RV
Article: ORGANIC LETTERS. 2013;15(5):1056-1059
Synthesis of Novel Aryl and Heteroaryl Acyl Sulfonimidamides via Pd-Catalyzed Carbonylation Using a Nongaseous Precursor
Borhade SR; Sandstrom A; Arvidsson PI
Article: TETRAHEDRON ASYMMETRY. 2013;24(2-3):134-141
Organocatalytic asymmetric cross-aldol reaction of 2-chloroethoxy acetaldehyde: diversity-oriented synthesis of chiral substituted 1,4-dioxanes and morpholines
Sawant RT; Stevenson J; Odell LR; Arvidsson PI
Article: RSC MEDICINAL CHEMISTRY. 2013;4(2):422-431
Triazolopyrimidinones as γ-secretase modulators: structure-activity relationship, modulator profile, and in vivo profiling
Yngve U; Paulsen K; Macsari I; Sundstrom M; Santangelo E; Linde C; Bogar K; Lake F; Besidski Y; Malmborg J; Stromberg K; Appelkvist P; Radesater A-C; Olsson F; Bergstrom D; Klintenberg R; Arvidsson PI
Article: JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY. 2013;28(1):78-88
Synthesis, 2D-NMR and molecular modelling studies of pentacycloundecane lactam-peptides and peptoids as potential HIV-1 wild type C-SA protease inhibitors
Makatini MM; Petzold K; Alves CN; Arvidsson PI; Honarparvar B; Govender P; Govender T; Kruger HG; Sayed Y; Lameira J; Maguire GEM; Soliman MES
Article: JOURNAL OF NEUROSCIENCE. 2012;32(48):17297-17305
Alzheimer's Disease: Presenilin 2-Sparing γ-Secretase Inhibition Is a Tolerable Aβ Peptide-Lowering Strategy
Borgegard T; Gustavsson S; Nilsson C; Parpal S; Klintenberg R; Berg A-L; Rosqvist S; Serneels L; Svensson S; Olsson F; Jin S; Yan H; Wanngren J; Jureus A; Ridderstad-Wollberg A; Wollberg P; Stockling K; Karlstrom H; Malmberg A; Lund J; Arvidsson PI; De Strooper B; Lendahl U; Lundkvist J
Journal article: CHEMINFORM. 2012;43(45):no
ChemInform Abstract: Asymmetric Conjugate Addition of Thioglycolate to a Range of Chalcones Using Tetrahydroisoquinoline (TIQ) N,N′‐Dioxide Ligands.
Chakka SK; Cele ZED; Sosibo SC; Francis V; Arvidsson PI; Kruger HG; Maquire GEM; Govender T
Article: CHEMISTRY & BIODIVERSITY. 2012;9(11):2442-2452
Imidazopyridine-Based Inhibitors of Glycogen Synthase Kinase 3: Synthesis and Evaluation of Amide Isostere Replacements of the Carboxamide Scaffold
Yngve U; Soderman P; Svensson M; Rosqvist S; Arvidsson PI
Article: DRUG METABOLISM AND DISPOSITION. 2012;40(11):2185-2191
Novel Bioactivation Mechanism of Reactive Metabolite Formation from Phenyl Methyl-Isoxazoles
Bylund J; Macsari I; Besidski Y; Olofsson S; Petersson C; Arvidsson PI; Bueters T
Article: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY. 2012;57:459-467
Synthesis, screening and computational investigation of pentacycloundecane-peptoids as potent CSA-HIV PR inhibitors
Makatini MM; Petzold K; Arvidsson PI; Honarparvar B; Govender T; Maguire GEM; Parboosing R; Sayed Y; Soliman MES; Kruger HG
Article: TETRAHEDRON. 2012;68(36):7456-7462
Synthesis and arylation of unprotected sulfonimidamides
Maldonado MF; Sehgelmeble F; Bjarnemark F; Svensson M; Ahman J; Arvidsson PI
Article: JOURNAL OF MEDICINAL CHEMISTRY. 2012;55(15):6866-6880
3-Oxoisoindoline-1-carboxamides: Potent, State-Dependent Blockers of Voltage-Gated Sodium Channel Na_V1.7 with Efficacy in Rat Pain Models
Macsari I; Besidski Y; Csjernyik G; Nilsson LI; Sandberg L; Yngve U; Ahlin K; Bueters T; Eriksson AB; Lund P-E; Venyike E; Oerther S; Blakeman KH; Luo L; Arvidsson PI
Journal article: ALZHEIMERS & DEMENTIA. 2012;8(4S_Part_19):p703-p704
P4‐192: Mechanism of gamma‐secretase‐mediated APP processing and modulation
Lundkvist J; Olsson F; Schmidt S; Althoff V; Jin S; Lendahl U; Multhaup G; Arvidsson P
Article: EUROPEAN JOURNAL OF ORGANIC CHEMISTRY. 2012;2012(17):3331-3337
Microwave-Assisted Synthesis of Guanidine Organocatalysts Bearing a Tetrahydroisoquinoline Framework and Their Evaluation in Michael Addition Reactions
Naicker T; Arvidsson PI; Kruger HG; Maguire GEM; Govender T
Journal article: CHEMMEDCHEM. 2012;7(6):938
Inside Cover: Pentacycloundecane‐diol‐Based HIV‐1 Protease Inhibitors: Biological Screening, 2D NMR, and Molecular Simulation Studies (ChemMedChem 6/2012)
Honarparvar B; Makatini MM; Pawar SA; Petzold K; Soliman MES; Arvidsson PI; Sayed Y; Govender T; Maguire GEM; Kruger HG
Article: CHEMMEDCHEM. 2012;7(6):1009-1019
Pentacycloundecane-diol-Based HIV-1 Protease Inhibitors: Biological Screening, 2D NMR, and Molecular Simulation Studies
Honarparvar B; Makatini MM; Pawar SA; Petzold K; Soliman MES; Arvidsson PI; Sayed Y; Govender T; Maguire GEM; Kruger HG
Journal article: CHEMINFORM. 2012;43(19):no
ChemInform Abstract: Tetrahydroisoquinoline‐Based N‐Oxides as Chiral Organocatalysts for the Asymmetric Allylation of Aldehydes.
Naicker T; Arvidsson PI; Kruger HG; Maguire GEM; Govender T
Article: TETRAHEDRON ASYMMETRY. 2012;23(8):616-622
Asymmetric conjugate addition of thioglycolate to a range of chalcones using tetrahydroisoquinoline (TIQ) N,N′-dioxide ligands
Chakka SK; Cele ZED; Sosibo SC; Francis V; Arvidsson PI; Kruger HG; Maguire GEM; Govender T
Article: CHEMMEDCHEM. 2012;7(3):396-399
Sulfonimidamides as Sulfonamides Bioisosteres: Rational Evaluation through Synthetic, in Vitro, and in Vivo Studies with γ-Secretase Inhibitors
Sehgelmeble F; Janson J; Ray C; Rosqvist S; Gustavsson S; Nilsson LI; Minidis A; Holenz J; Rotticci D; Lundkvist J; Arvidsson PI
Article: JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY. 2012;12(3):2179-2184
Interaction of β-Amyloid Interactions with Peptide Functionalized Gold Nanoparticles
Hemmaragala NM; Arvidsson PI; Maguire GEM; Kruger HG; Govender T
Article: EUROPEAN JOURNAL OF ORGANIC CHEMISTRY. 2011;2011(34):6923-6932
Tetrahydroisoquinoline-Based N-Oxides as Chiral Organocatalysts for the Asymmetric Allylation of Aldehydes
Naicker T; Arvidsson PI; Kruger HG; Maguire GEM; Govender T
Article: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY. 2011;46(9):3976-3985
Synthesis and structural studies of pentacycloundecane-based HIV-1 PR inhibitors: A hybrid 2D NMR and docking/QM/MM/MD approach
Makatini MM; Petzold K; Sriharsha SN; Ndlovu N; Soliman MES; Honarparvar B; Parboosing R; Naidoo A; Arvidsson PI; Sayed Y; Govender P; Maguire GEM; Kruger HG; Govender T
Article: BIOORGANIC & MEDICINAL CHEMISTRY LETTERS. 2011;21(13):3871-3876
Phenyl isoxazole voltage-gated sodium channel blockers: Structure and activity relationship
Macsari I; Sandberg L; Besidski Y; Gravenfors Y; Ginman T; Bylund J; Bueters T; Eriksson AB; Lund P-E; Venyike E; Arvidsson PI
Article: BIOORGANIC & MEDICINAL CHEMISTRY LETTERS. 2011;21(8):2274-2277
Pentacycloundecane-based inhibitors of wild-type C-South African HIV-protease
Makatini MM; Petzold K; Sriharsha SN; Soliman MES; Honarparvar B; Arvidsson PI; Sayed Y; Govender P; Maguire GEM; Kruger HG; Govender T
Article: TETRAHEDRON ASYMMETRY. 2010;21(23):2859-2867
Novel tetrahydroisoquinoline based organocatalysts for asymmetric Diels-Alder reactions: insight into the catalytic mode using ROESY NMR and DFT studies
Naicker T; Petzold K; Singh T; Arvidsson PI; Kruger HG; Maguire GEM; Govender T
Article: BIOORGANIC & MEDICINAL CHEMISTRY. 2010;18(16):5896-5902
In vitro ADMET and physicochemical investigations of poly-N-methylated peptides designed to inhibit Aβ aggregation
Bose PP; Chatterjee U; Hubatsch I; Artursson P; Govender T; Kruger HG; Bergh M; Johansson J; Arvidsson PI
Article: MAGNETIC RESONANCE IN CHEMISTRY. 2010;48(6):435-442
Synthesis and NMR elucidation of novel pentacycloundecane-based peptides
Altaib MS; Arvidsson PI; Govender T; Maguire GEM; Makatini M; Onajole OK; Kruger HG
Article: ACS CHEMICAL NEUROSCIENCE. 2010;1(4):315-324
Effects of Congo Red on Aβ_1-40 Fibril Formation Process and Morphology
Bose PP; Chatterjee U; Xie L; Johansson J; Gothelid E; Arvidsson PI
Article: BIOORGANIC & MEDICINAL CHEMISTRY LETTERS. 2010;20(4):1360-1362
Design and study of peptide-based inhibitors of amylin cytotoxicity
Muthusamy K; Arvidsson PI; Govender P; Kruger HG; Maguire GEM; Govender T
Article: BIOPOLYMERS. 2010;94(3):323-330
Microwave Assisted SPPS of Amylin and Its Toxicity of the Pure Product to RIN-5F Cells
Muthusamy K; Albericio F; Arvidsson PI; Govender P; Kruger HG; Maguire GEM; Govender T
Article: JOURNAL OF MEDICINAL CHEMISTRY. 2009;52(24):8002-8009
Poly-N-methylated Amyloid β-Peptide (Aβ) C-Terminal Fragments Reduce Aβ Toxicity in Vitro and in Drosophila melanogaster
Bose PP; Chatterjee U; Nerelius C; Govender T; Norstrom T; Gogoll A; Sandegren A; Gothelid E; Johansson J; Arvidsson PI
Article: TETRAHEDRON ASYMMETRY. 2009;20(16):1871-1876
Synthesis and application of novel imidazole and 1H-tetrazolic acid containing catalysts in enantioselective organocatalyzed Diels-Alder reactions
Hartikka A; Hojabri L; Bose PP; Arvidsson PI
Article: SOUTH AFRICAN JOURNAL OF CHEMISTRY-SUID-AFRIKAANSE TYDSKRIF VIR CHEMIE. 2009;62:60-U78
Application of (S,S)-Pentacycloundecane bis(4-Phenyloxazoline) as a Novel Chiral Ligand for Catalysis of the Asymmetric Diels-Alder Reaction of Cyclopentadiene with 3-Acryloyl-2-oxazolidinone
Arvidsson PI; Govender T; Kruger HG; Maguire GEM; Naicker T
Article: INTERNATIONAL JOURNAL OF PEPTIDE RESEARCH AND THERAPEUTICS. 2008;14(3):219-222
Facile synthesis of N-protected amino acid assisted by microwave irradiation
Zhang S; Arvidsson PI
Article: JOURNAL OF ORGANIC CHEMISTRY. 2008;73(14):5272-5278
Design and synthesis of glycosylated β³-peptides capable of folding into the 3₁₄-helical conformation in water
Norgren AS; Arvidsson PI
Article: PHYSICAL REVIEW B. 2008;77(15):155407
Cobalt-doped β-peptide nanotubes:: A class of spintronic materials
Sanyal B; Eriksson O; Arvidsson PI
Journal article: CHEMINFORM. 2007;38(49):no
Tetrazolic Acid Functionalized Dihydroindol: Rational Design of a Highly Selective Cyclopropanation Organocatalyst.
Hartikka A; Arvidsson PI
Journal article: CHEMINFORM. 2007;38(48):no
Application of Novel Sulfonamides in Enantioselective Organocatalyzed Cyclopropanation.
Hartikka A; Slosarczyk AT; Arvidsson PI
Article: JOURNAL OF MEDICINAL CHEMISTRY. 2007;50(21):5238-5242
β- and γ-di- and tripeptides as potential substrates for the oligopeptide transporter hPep t1
Hubatsch I; Arvidsson PI; Seebach D; Luthman K; Artursson P
Article: JOURNAL OF ORGANIC CHEMISTRY. 2007;72(15):5874-5877
Tetrazolic acid functionalized dihydroindol: Rational design of a highly selective cyclopropanation organocatalyst
Hartikka A; Arvidsson PI
Journal article: CHEMINFORM. 2007;38(28):no
A New Imidazole‐Containing Imidazolidinone Catalyst for Organocatalyzed Asymmetric Conjugate Addition of Nitroalkanes to Aldehydes.
Hojabri L; Hartikka A; Moghaddam FM; Arvidsson PI
Article: TETRAHEDRON ASYMMETRY. 2007;18(12):1403-1409
Application of novel sulfonamides in enantioselective organocatalyzed cyclopropanation
Hartikka A; Slosarczyk AT; Arvidsson PI
Article: ADVANCED SYNTHESIS & CATALYSIS. 2007;349(4-5):740-748
A new imidazole-containing imidazolidinone catalyst for organocatalyzed asymmetric conjugate addition of nitroalkanesto aldehydes
Hojabri L; Hartikka A; Moghaddam FM; Arvidsson PI
Article: JOURNAL OF MOLECULAR RECOGNITION. 2007;20(2):132-138
Biomolecular recognition of glycosylated β³-peptides, by GaINAc specific lectins
Norgren AS; Geitmann M; Danielson UH; Arvidsson PI
Journal article: CHEMINFORM. 2006;37(50):no
Organocatalytic Synthesis of Chiral Benzopyrans.
Govender T; Hojabri L; Moghaddam FM; Arvidsson PI
Article: ORGANIC LETTERS. 2006;8(20):4533-4536
Synthesis and circular dichroism spectroscopic investigations of oligomeric β-peptoids with α-chiral side chains
Norgren AS; Zhang S; Arvidsson PI
Article: JOURNAL OF ORGANIC CHEMISTRY. 2006;71(18):6814-6821
β²-amino acids in the design of conformationally homogeneous cyclo-peptide scaffolds
Norgren AS; Buttner F; Prabpai S; Kongsaeree P; Arvidsson PI
Article: TETRAHEDRON ASYMMETRY. 2006;17(12):1763-1767
Organocatalytic synthesis of chiral benzopyrans
Govender T; Hojabri L; Moghaddam FM; Arvidsson PI
Journal article: CHEMINFORM. 2006;37(26):no
Facile Synthesis of Fmoc‐N‐Methylated α‐ and β‐Amino Acids.
Govender T; Arvidsson PI
Journal article: EUROPEAN JOURNAL OF ORGANIC CHEMISTRY. 2006;2006(12):2857
5‐(Pyrrolidine‐2‐yl)tetrazole: Rationale for the Increased Reactivity of the Tetrazole Analogue of Proline in Organocatalyzed Aldol Reactions
Hartikka A; Arvidsson PI
Journal article: CHEMINFORM. 2006;37(20):no
Poly‐N‐methylated α‐Peptides: Synthesis and X‐Ray Structure Determination of β‐Strand Forming Foldamers
Zhang S; Prabpai S; Kongsaeree P; Arvidsson PI
Article: TETRAHEDRON LETTERS. 2006;47(11):1691-1694
Facile synthesis of Fmoc-N-methylated α- and β-amino acids
Govender T; Arvidsson PI
Journal article: CHEMINFORM. 2006;37(9):no
5‐(Pyrrolidine‐2‐yl)tetrazole: Rationale for the Increased Reactivity of the Tetrazole Analogue of Proline in Organocatalyzed Alcol Reactions.
Hartikka A; Arvidsson PI
Article: CHEMICAL COMMUNICATIONS. 2006;(5):497-499
Poly-N-methylated α-peptides: synthesis and X-ray structure determination of β-strand forming foldamers
Zhang SD; Prabpai S; Kongsaeree P; Arvidsson PI
Journal article: CHEMINFORM. 2006;37(1):no
An Improved Synthesis of Fmoc‐N‐methyl‐α‐amino Acids.
Zhang S; Govender T; Norstroem T; Arvidsson PI
Article: JOURNAL OF THE AMERICAN CHEMICAL SOCIETY. 2005;127(43):15083-15090
Mechanistic insights into the phosphine-free RuCp^☆-diamine-catalyzed hydrogenation of aryl ketones: Experimental and theoretical evidence for an alcohol-mediated dihydrogen activation
Hedberg C; Källström K; Arvidsson PI; Brandt P; Andersson PG
Article: CHEMISTRY-A EUROPEAN JOURNAL. 2005;11(21):6145-6158
Cyclic β-tetra- and pentapeptides: Synthesis through on-resin Cyclization and conformational studies by X-ray, NMR and CD spectroscopy and theoretical calculations
Büttner F; Norgren AS; Zhang SD; Prabpai S; Kongsaeree P; Arvidsson PI
Article: EUROPEAN JOURNAL OF ORGANIC CHEMISTRY. 2005;2005(20):4287-4295
5-(Pyrrolidine-2-yl)tetrazole: Rationale for the increased reactivity of the tetrazole analogue of proline in organocatalyzed aldol reactions
Hartikka A; Arvidsson PI
Article: JOURNAL OF ORGANIC CHEMISTRY. 2005;70(17):6918-6920
An improved synthesis of Fmoc-N-methyl-α-amino acids
Zhang S; Govender T; Norström T; Arvidsson PI
Article: ORGANIC & BIOMOLECULAR CHEMISTRY. 2005;3(8):1359-1361
Functionalized foldamers: synthesis and characterization of a glycosylated β-peptide 3₁₄-helix conveying the T_N-antigen
Norgren AS; Arvidsson PI
Article: CHEMISTRY & BIODIVERSITY. 2005;2(3):401-420
Exploring the antibacterial and hemolytic activity of shorter- and longer-chain β- α,β-, and γ-peptides, and of β-peptides from β²-3-aza- and β₃-2-methylidene-amino acids bearing proteinogenic side chains - A survey
Arvidsson PI; Ryder NS; Weiss HM; Hook DF; Escalante J; Seebach D
Article: HELVETICA CHIMICA ACTA. 2004;87(11):2735-2741
Cyclo(β-Asp-β³-hVal-β³-hLys) - Solid-phase synthesis and solution structure of a water soluble β-tripeptide
Büttner F; Erdélyi M; Arvidsson PI
Article: TETRAHEDRON ASYMMETRY. 2004;15(12):1831-1834
Rational design of asymmetric organocatalysts - increased reactivity and solvent scope with a tetrazolic acid
Hartikka A; Arvidsson PI
Journal article: JOURNAL OF HIGH ENERGY PHYSICS. 2004;(5)
The (2,0) supersymmetric theory of tensor multiplets and self-dual strings in six dimensions - art. no. 048
Arvidsson P; Flink E; Henningson M
Article: CHEMBIOCHEM. 2003;4(12):1345-1347
Antibiotic and hemolytic activity of a β²/β³ peptide capable of folding into a 12/10-helical secondary structure
Arvidsson PI; Ryder NS; Weiss HM; Gross G; Kretz O; Woessner R; Seebach D
Journal article: CHEMINFORM. 2003;34(46):no
Chinchona Alkaloid Derived Ligands in Catalytic Asymmetric Transfer Hydrogenation.
Hartikka A; Modin SA; Andersson PG; Arvidsson PI
Journal article: JOURNAL OF HIGH ENERGY PHYSICS. 2003;(11)
Supersymmetric coupling of a self-dual string to a (2,0) tensor multiplet background - art. no. 015
Arvidsson P; Flink E; Henningson M
Article: ORGANIC & BIOMOLECULAR CHEMISTRY. 2003;1(14):2522-2526
Cinchona alkaloid derived ligands in catalytic asymmetric transfer hydrogenation
Hartikka A; Modin SA; Andersson PG; Arvidsson PI
Journal article: JOURNAL OF HIGH ENERGY PHYSICS. 2003;(6)
Free tensor multiplets and strings in spontaneously broken six-dimensional (2,0) theory - art. no. 039
Arvidsson P; Flink E; Henningson M
Article: HELVETICA CHIMICA ACTA. 2003;86(5):1522-1553
Syntheses and CD-spectroscopic investigations of longer-chain β-peptides: Preparation by solid-phase couplings of single amino acids, dipeptides, and tripeptides
Arvidsson PI; Frackenpohl J; Seebach D
Journal article: JOURNAL OF CHROMATOGRAPHY A. 2003;986(2):275-290
Direct chromatographic capture of enzyme from crude homogenate using immobilized metal affinity chromatography on a continuous supermacroporous adsorbent
Arvidsson P; Plieva FM; Lozinsky VI; Galaev IY; Mattiasson B
Article: HELVETICA CHIMICA ACTA. 2002;85(11):3814-3822
On the mechanism of internal ortho-lithiation in a mixed complex between BuLi and a chiral lithium amide
Arvidsson PI; Hilmersson G; Davidsson Ö
Article: BIOPHARMACEUTICS & DRUG DISPOSITION. 2002;23(6):251-262
The outstanding metabolic stability of a ¹⁴C-labeled β-nonapeptide in rats -: in vitro and in vivo pharmacokinetic studies
Wiegand H; Wirz B; Schweitzer A; Camenisch GP; Perez MIR; Gross G; Woessner R; Voges R; Arvidsson PI; Frackenpohl J; Seebach D
Article: JOURNAL OF THE CHEMICAL SOCIETY, PERKIN TRANSACTIONS 2. 2002;(4):763-767
Stereoselective solvent induced 1,3-proton transfer of an allylic alkoxide to a homoallylic alkoxide catalysed by a chiral lithium amide
Hansson M; Arvidsson PI; Lill SON; Ahlberg P
Article: HELVETICA CHIMICA ACTA. 2001;84(11):3503-3510
Linear, peptidase-resistant β²/β³-di- and α/β³-tetrapeptide derivatives with nanomolar affinities to a human somatostatin receptor - Preliminary communication
Seebach D; Rueping M; Arvidsson PI; Kimmerlin T; Micuch P; Noti C; Langenegger D; Hoyer D
Article: CHEMISTRY-A EUROPEAN JOURNAL. 2001;7(19):4117-4125
Computational, ReactIR-, and NMR-spectroscopic investigations on the chiral formyl anion equivalent N-(α-lithiomethylthiomethyl)-4-isopropyl-5,5-diphenyloxazolidin-2-one and related compounds
Gaul C; Arvidsson PI; Bauer W; Gawley RE; Seebach D
Article: CHEMBIOCHEM. 2001;2(10):771-773
On the antimicrobial and hemolytic activities of amphiphilic β-peptides
Arvidsson PI; Frackenpohl J; Ryder NS; Liechty B; Petersen F; Zimmermann H; Camenisch GP; Woessner R; Seebach D
Article: CHEMBIOCHEM. 2001;2(6):445-455
The outstanding biological stability of β- and γ-peptides toward proteolytic enzymes:: An in vitro investigation with fifteen peptidases
Frackenpohl J; Arvidsson PI; Schreiber JV; Seebach D
Journal article: JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES. 2001;753(2):279-285
Polymer versus monomer as displacer in immobilized metal affinity chromatography
Arvidsson P; Ivanov AE; Galaev IY; Mattiasson B
Article: HELVETICA CHIMICA ACTA. 2001;84(2):271-279
The miraculous CD spectra (and secondary structures?) of β-peptides as they grow longer -: Preliminary communication
Seebach D; Schreiber JV; Arvidsson PI; Frackenpohl J
Article: CHEMICAL COMMUNICATIONS. 2001;(7):649-650
Design, machine synthesis, and NMR-solution structure of a β-heptapeptide forming a salt-bridge stabilised 3₁₄-helix in methanol and in water
Arvidsson PI; Rueping M; Seebach D
Article: CHIMIA. 2001;55(4):345-353
From the biopolymer PHB to biological investigations of unnatural β- and γ-peptides
Seebach D; Albert M; Arvidsson PI; Rueping M; Schreiber JV
Article: JOURNAL OF THE AMERICAN CHEMICAL SOCIETY. 2000;122(38):9310-9311
The structure of a chiral lithium amidocuprate in solution determined by multinuclear NMR spectroscopy
Eriksson J; Arvidsson PI; Davidsson Ö
Article: ANGEWANDTE CHEMIE-INTERNATIONAL EDITION. 2000;39(8):1467-1470
⁶Li and ¹⁵N NMR data as a probe for the influence of solvent and intramolecular solvation on the solution-state structures of chiral lithium amides
Arvidsson PI; Davidsson O
Journal article: ANGEWANDTE CHEMIE-INTERNATIONAL EDITION. 2000;112(8):1527-1530
6Li and 15N NMR Data as a Probe for the Influence of Solvent and Intramolecular Solvation on the Solution‐State Structures of Chiral Lithium Amides
Arvidsson PI; Davidsson Ö
Article: CHEMISTRY-A EUROPEAN JOURNAL. 1999;5(8):2356-2361
Solution structure of a dilithiumamide/diethylzinc heterocomplex that catalyzes asymmetric alkylation reactions
Eriksson J; Arvidsson PI; Davidsson Ö
Article: CHEMISTRY-A EUROPEAN JOURNAL. 1999;5(8):2348-2355
Rational design of chiral lithium amides for asymmetric alkylation reactions -: NMR spectroscopic studies of mixed lithium amide/alkyllithium complexes
Arvidsson PI; Hilmersson G; Davidsson Ö
Journal article: CHEMISTRY-A EUROPEAN JOURNAL. 1999;5(8):2348-2355
Rational Design of Chiral Lithium Amides for Asymmetric Alkylation Reactions-NMR Spectroscopic Studies of Mixed Lithium Amide/Alkyllithium Complexes
Arvidsson PI; Hilmersson G; Davidsson Ö
Journal article: CHEMISTRY-A EUROPEAN JOURNAL. 1999;5(4):1348-1354
Intraaggregate Fluxional Lithium and Carbanion Exchanges in a Chiral Lithium Amide/n-Butyllithium Mixed Tetramer Directly Observed by Multinuclear NMR
Arvidsson PI; Ahlberg P; Hilmersson G
Article: CHEMISTRY-A EUROPEAN JOURNAL. 1999;5(4):1348-1354
Intraaggregate fluxional lithium and carbanion exchanges in a chiral lithium amide/n-butyllithium mixed tetramer directly observed by multinuclear NMR
Arvidsson PI; Ahlberg P; Hilmersson G
Article: JOURNAL OF THE AMERICAN CHEMICAL SOCIETY. 1999;121(9):1883-1887
Stereoselective diamine chelates of a chiral lithium amide dimer: New insights into the coordination chemistry of chiral lithium amides
Arvidsson PI; Hilmersson G; Ahlberg P
Article: TETRAHEDRON ASYMMETRY. 1999;10(3):527-534
Enantioselective butylation of aliphatic aldehydes by mixed chiral lithium amide n-BuLi dimers
Arvidsson PI; Davidsson O; Hilmersson G
Article: TETRAHEDRON ASYMMETRY. 1999;10(2):265-279
Computational study of solvation and stereoselectivity in deprotonation of cyclohexene oxide by a chiral lithium amide
Lill SON; Arvidsson PI; Ahlberg P
Article: ENANTIOMER. 1999;4(5):445-450
(S)-2-(1-pyrrolidinylmethyl)pyrrolidine•HCl crystal structure and use in the chiral lithium amide base mediated rearrangement of cyclohexene oxide
Arvidsson PI; Khan AZQ; Hilmersson G; Davidsson O; Håkansson M
Article: JOURNAL OF THE AMERICAN CHEMICAL SOCIETY. 1998;120(32):8143-8149
Toward solution-state structure. A ⁶Li,¹H HOESY NMR, X-ray diffraction, semiempirical (PM3, MNDO), and ab initio computational study of a chiral lithium amide
Hilmersson G; Arvidsson PI; Davidsson Ö; Håkansson M
Journal article: CHEMINFORM. 1998;29(31):no
ChemInform Abstract: A New Chiral Lithium Amide Based on (S)‐2‐[1‐(3,3‐Dimethyl)pyrrolidinylmethyl]pyrrolidine—Synthesis, NMR Studies and Use in the Enantioselective Deprotonation of Cyclohexene Oxide.
KHAN AZ; DE GROOT RW; ARVIDSSON PI; DAVIDSSON O
Journal article: APPLIED MICROBIOLOGY AND BIOTECHNOLOGY. 1998;49(6):677-681
Monitoring nitric oxide from immobilised denitrifying bacteria, Pseudomonas stutzeri, by the use of chemiluminescence
Arvidsson P; Nilsson K; Håkanson H; Mattiasson B
Article: CANADIAN JOURNAL OF CHEMISTRY. 1998;76(6):795-799
Solvent-induced stereospecific isomerization of an allylic alcohol to a homoallylic alcohol catalyzed by a chiral lithium amide
Arvidsson PI; Hansson M; Khan AZQ; Ahlberg P
Journal article: JOURNAL OF CHROMATOGRAPHY A. 1998;803(1-2):227-233
Analysis of nonpolar heterocyclic amines in cooked foods and meat extracts using gas chromatography mass spectrometry
Skog K; Solyakov A; Arvidsson P; Jägerstad M
Article: TETRAHEDRON ASYMMETRY. 1998;9(7):1223-1229
A new chiral lithium amide based on (S)-2-[1-(3,3-dimethyl)pyrrolidinylmethyl] pyrrolidine -: synthesis, NMR studies and use in the enantioselective deprotonation of cyclohexene oxide
Khan AZQ; de Groot RW; Arvidsson PI; Davidsson O
Article: ACTA CHEMICA SCANDINAVICA. 1998;52(3):280-284
Computational study of the mechanism of isomerization of allyl alcohol into homoallyl alcohol by lithium amide
Lill SON; Arvidsson PI; Ahlberg P
Journal article: JOURNAL OF MOLECULAR RECOGNITION. 1998;11(1-6):255-260
Protein displacement in dye-ligand chromatography using neutral and charged polymers
Galaev IY; Arvidsson P; Mattiasson B
Article: ORGANOMETALLICS. 1997;16(15):3352-3362
Chiral lithium amide solute complexes: X-ray crystallographic and NMR spectroscopic studies
Hilmersson G; Arvidsson PI; Davidsson O; Hakansson M
Journal article: JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY. 1996;66(1):15-18
Analysis of cyclodextrins using a calorimetric biosensor
Kolb M; Zentgraf B; Arvidsson P; Mattiasson B; Danielsson B
Journal article: THERMOCHIMICA ACTA. 1996;277:1-6
Biochemical analysis of cyclodextrins using an enzyme thermistor
Kolb M; Zentgraf B; Mattiasson B; Arvidsson P; Danielsson B
Article: TETRAHEDRON ASYMMETRY. 1996;7(2):399-402
Solvent induced isomerization of 2-cyclohexen-1-ol to 3-cyclohexen-1-ol by a chiral lithium amide
Khan AZQ; Arvidsson PI; Ahlberg P
Journal article: JOURNAL OF CHROMATOGRAPHY A. 1995;710(2):259-266
POLYMER DISPLACEMENT IN DYE-AFFINITY CHROMATOGRAPHY
GALAEV IY; ARVIDSSON P; MATTIASSON B
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Supplementary methods for "Pharmacological targeting of MTHFD2 suppresses acute myeloid leukemia by inducing thymidine depletion and replication stress"
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Review: BRAIN RESEARCH. 2021;1767:147524
Potential of brain mast cells for therapeutic application in the immune response to bacterial and viral infections
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Review: EXPERT OPINION ON THERAPEUTIC PATENTS. 2020;30(7):541-555
A 2018-2019 patent review of metallo beta-lactamase inhibitors
Reddy N; Shungube M; Arvidsson PI; Baijnath S; Kruger HG; Govender T; Naicker T
Conference publication: BRITISH JOURNAL OF PHARMACOLOGY. 2020;177(11):2631-2632
An in silico 360 concept for the triage and selection of drug development compounds
Southan C; Arvidsson P
Review: ADVANCED SYNTHESIS & CATALYSIS. 2018;360(16):2976-3001
Sulfonimidamides: Synthesis and Applications in Preparative Organic Chemistry
Nandi GC; Arvidsson PI
Review: EUROPEAN JOURNAL OF ORGANIC CHEMISTRY. 2018;2018(27-28):3648-3666
Sulfonyl Fluorides (SFs): More Than Click Reagents?
Chinthakindi PK; Arvidsson PI
Review: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY. 2017;133:287-308
Synthetic approaches to radiochemical probes for imaging of bacterial infections
Dutta J; Naicker T; Ebenhan T; Kruger HG; Arvidsson PI; Govender T
Review: ANGEWANDTE CHEMIE-INTERNATIONAL EDITION. 2017;56(15):4100-4109
Sulfonimidamides in Medicinal and Agricultural Chemistry
Chinthakindi PK; Naicker T; Thota N; Govender T; Kruger HG; Arvidsson PI
Review: DRUG DISCOVERY TODAY. 2016;21(10):1690-1698
Open for collaboration: an academic platform for drug discovery and development at SciLifeLab
Arvidsson PI; Sandberg K; Forsberg-Nilsson K
Review: CHEMICAL REVIEWS. 2016;116(16):9375-9437
Enantioselective Organocatalyzed Transformations of β-Ketoesters
Govender T; Arvidsson PI; Maguire GEM; Kruger HG; Naicker T
Book chapter: REFERENCE MODULE IN CHEMISTRY, MOLECULAR SCIENCES AND CHEMICAL ENGINEERING. 2015;p.
Cyclopropanation Reactions☆
Arvidsson PI; Bose PP; Naicker T
Book chapter: COMPREHENSIVE CHIRALITY. 2012;p. 293-317
6.11 Cyclopropanation Reactions
Arvidsson PI; Bose PP; Naicker T
Conference publication: ACS NATIONAL MEETING BOOK OF ABSTRACTS. 2011;242
Phenyl isoxazole voltage-gated sodium channel blockers: Structure and activity relationship
Macsari I; Sandberg L; Besidski Y; Gravenfors Y; Ginman T; Bylund J; Bueters T; Arvidsson PI
Conference publication: JOURNAL OF PEPTIDE SCIENCE. 2007;13(11):717-727
Glycosylated foldamers:: synthesis of carbohydrate- modified β³hSer and incorporation into β-peptides
Norgren AS; Norberg T; Arvidssona PI
Conference publication: JOURNAL OF PEPTIDE SCIENCE. 2006;12:101
Synthesis and conformational studies of glycosylated β-peptides
Norgren AS; Arvidsson PI
Conference publication: JOURNAL OF PEPTIDE SCIENCE. 2006;12:115
Synthesis and structural investigationd of linear and cyclic A-chiral N-substituted B-peptoids.
Norgren AS; Zhang S; Arvidsson PI
Conference publication: JOURNAL OF PEPTIDE SCIENCE. 2006;12:115
Synthesis and conformational analysis of mixed cyclic A/B2-tetrapeptides
Norgren AS; Buttner F; Arvidsson PI
Conference publication: JOURNAL OF PEPTIDE SCIENCE. 2004;10:200
SYNTHESIS AND STRUCTURAL INVESTIGATIONS OF O-GLYCOSYLATED B-AMINO ACIDS AND B-PEPTIDES
Norgren AS; Arvidsson PI
Book chapter: PEPTIDES: THE WAVE OF THE FUTURE: AMERICAN PEPTIDE SYMPOSIA. 2001;p. 275-276
Recent Advances in the Solid-Phase Synthesis of Long-Chain β-Peptides
Frackenpohl J; Schreiber JV; Arvidsson PI; Seebach D

Grants

Cancer-specific targeted protein degradation through FBXO22
Novo Nordisk Foundation
1 February 2022 - 31 August 2023
BIPOD
SciLifeLabs Sweden
1 October 2018

Employments

Director Drug Discovery & Development, Science for Life Laboratory, Karolinska Institute, Drug Discovery & Development, Science for Life Laboratory, 2013-
Specialist, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, 2013-
Professor, Pharmacy, University of KwaZulu-Natal, 2010-
Adjunct professor, Chemistry and Medicinal chemistry, Uppsala University, 2007-2013
Director, AstraZeneca (Sweden), 2006-2013

Degrees and Education

Docent, Uppsala Universitet, 2005

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Employments

Degrees and Education

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