Pawel Baranczewski

Publications
Public outreach and news

Articles

Article: NATURE. 2014;508(7495):215-221
MTH1 inhibition eradicates cancer by preventing sanitation of the dNTP pool
Gad H; Koolmeister T; Jemth A-S; Eshtad S; Jacques SA; Strom CE; Svensson LM; Schultz N; Lundback T; Einarsdottir BO; Saleh A; Gokturk C; Baranczewski P; Svensson R; Berntsson RP-A; Gustafsson R; Stromberg K; Sanjiv K; Jacques-Cordonnier M-C; Desroses M; Gustavsson A-L; Olofsson R; Johansson F; Homan EJ; Loseva O; Brautigam L; Johansson L; Hoglund A; Hagenkort A; Pham T; Altun M; Gaugaz FZ; Vikingsson S; Evers B; Henriksson M; Vallin KSA; Wallner OA; Hammarstrom LGJ; Wiita E; Almlof I; Kalderen C; Axelsson H; Djureinovic T; Puigvert JC; Haggblad M; Jeppsson F; Martens U; Lundin C; Lundgren B; Granelli I; Jensen AJ; Artursson P; Nilsson JA; Stenmark P; Scobie M; Berglund UW; Helleday T
Article: EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY. 2014;70(2):167-178
Assessment of interaction potential of AZD2066 using in vitro metabolism tools, physiologically based pharmacokinetic modelling and in vivo cocktail data.
Nordmark A; Andersson A; Baranczewski P; Wanag E; Ståhle L
Article: DRUG METABOLISM AND DISPOSITION. 2013;41(1):159-169
Effect of solvents on the time-dependent inhibition of CYP3A4 and the biotransformation of AZD3839 in human liver microsomes and hepatocytes.
Aasa J; Hu Y; Eklund G; Lindgren A; Baranczewski P; Malmquist J; Turek D; Bueters T
Article: DRUG METABOLISM AND DISPOSITION. 2011;39(4):644-652
Characterization of niflumic acid as a selective inhibitor of human liver microsomal UDP-glucuronosyltransferase 1A9: application to the reaction phenotyping of acetaminophen glucuronidation.
Miners JO; Bowalgaha K; Elliot DJ; Baranczewski P; Knights KM
Article: TOXICOLOGY. 2007;235(1-2):27-38
Metabolism of 2-substituted quinolines with antileishmanial activity studied in vitro with liver microsomes, hepatocytes and recombinantly expressed enzymes analyzed by LC/MS.
Desrivot J; Edlund P-O; Svensson R; Baranczewski P; Fournet A; Figadère B; Herrenknecht C
Article: JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS. 2006;40(5):1121-1130
Characterization of the cytochrome P450 enzymes and enzyme kinetic parameters for metabolism of BVT.2938 using different in vitro systems.
Baranczewski P; Edlund PO; Postlind H
Article: ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES. 2004;2(4):345-352
Development of an assay using 4-trifluoromethylumbelliferyl as a marker substrate for assessment of drug-drug interactions to multiple isoforms of UDP-glucuronosyltransferases.
Baranczewski P; Kallin A; Andersson A; Hagigi S; Aberg M; Postlind H; Mankowitz L
Article: CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION. 2004;13(6):1071-1078
Relationship between content and activity of cytochrome P450 and induction of heterocyclic amine DNA adducts in human liver samples In vivo and In vitro
Baranczewski P; Möller L
Article: JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS. 2004;309(2):711-719
Oxidation of protein tyrosine phosphatases as a pharmaceutical mechanism of action: a study using 4-hydroxy-3,3-dimethyl-2H-benzo[g]indole-2,5(3H)-dione.
Liljebris C; Baranczewski P; Björkstrand E; Byström S; Lundgren B; Tjernberg A; Warolén M; James SR
Article: BIOMARKERS. 2004;9(3):243-257
DNA adduct formation of 14 heterocyclic aromatic amines in mouse tissue after oral administration and characterization of the DNA adduct formed by 2-amino-9H-pyrido[2,3-b]indole (AαC), analysed by ³²P-HPLC
Baranczewski P; Gustafsson J; Möller L
Article: JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS. 2004;34(5):1079-1090
Identification of BVT.2938 metabolites by LC/MS and LC/MS/MS after in vitro incubations with liver microsomes and hepatocytes.
Edlund PO; Baranczewski P
Article: ARCHIVES OF TOXICOLOGY. 2002;76(3):178-186
Susceptibility factors and DNA adducts in peripheral blood mononuclear cells of aluminium smelter workers exposed to polycyclic aromatic hydrocarbons
Tuominen R; Baranczewski P; Warholm M; Hagmar L; Möller L; Rannug A
Article: ARCHIVES OF TOXICOLOGY. 2001;74(11):720-731
Formation of DNA adducts from oil-derived products analyzed by ³²P-HPLC
Akkineni LK; Zeisig M; Baranczewski P; Ekström LG; Möller L
Article: CARCINOGENESIS. 2000;21(11):2105-2111
Effects of human intestinal flora on mutagenicity of and DNA adduct formation from food and environmental mutagens
Hirayama K; Baranczewski P; Åkerlund JE; Midtvedt T; Möller L; Rafter J
Article: EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY. 2000;257(3):149-153
Analysis of aromatic DNA adducts in laryngeal biopsies
Banaszewski J; Szmeja Z; Szyfter W; Szyfter K; Baranczewski P; Möller L
Article: CHROMOSOME RESEARCH. 1998;6(1):59-63
The acetylation patterns of histones H3 and H4 along Vicia faba chromosomes are different.
Belyaev ND; Houben A; Baranczewski P; Schubert I
Article: CHROMOSOMA. 1997;106(3):193-197
Histone H4 acetylation in plant heterochromatin is altered during the cell cycle.
Belyaev ND; Houben A; Baranczewski P; Schubert I
Article: ENVIRONMENTAL AND MOLECULAR MUTAGENESIS. 1997;29(4):400-405
Removal of O6-methylguanine from plant DNA in vivo is accelerated under conditions of clastogenic adaptation.
Baranczewski P; Nehls P; Rieger R; Rajewsky MF; Schubert I
Article: ENVIRONMENTAL AND MOLECULAR MUTAGENESIS. 1997;29(4):394-399
Formation and repair of O6-methylguanine in recombination hot spots of plant chromosomes.
Baranczewski P; Nehls P; Rieger R; Pich U; Rajewsky MF; Schubert I
Article: EXPERIMENTAL ONCOLOGY. 1995;17(1):61-70
GENOTOXICITY STUDIES IN SEMICONDUCTOR INDUSTRY - PRIMARY DNA-DAMAGE BY WASTE SAMPLES RESULTING FROM PLASMA-ETCHING AS DETECTED BY P-32 POSTLABELING
BRAUN R; BARANCZEWSKI P; MERTEN H

All other publications

Review: PHARMACOLOGICAL REPORTS. 2006;58(4):453-472
Introduction to in vitro estimation of metabolic stability and drug interactions of new chemical entities in drug discovery and development.
Baranczewski P; Stańczak A; Sundberg K; Svensson R; Wallin A; Jansson J; Garberg P; Postlind H
Review: PHARMACOLOGICAL REPORTS. 2006;58(3):341-352
Introduction to early in vitro identification of metabolites of new chemical entities in drug discovery and development.
Baranczewski P; Stańczak A; Kautiainen A; Sandin P; Edlund P-O
Corrigendum: ARCHIVES OF TOXICOLOGY. 2001;75(2):123-125
Formation of DNA adducts from oil-derived products analyzed by ³²P-HPLC (vol 74, pg 720, 2001)
Akkineni LK; Zeisig M; Baranczewski P; Ekström LG; Möller L

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