Paolo Parini

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Public outreach and news

About me

Paolo Parini is a Professor of Clinical Chemistry and studies cardiometabolic diseases at the molecular level. He is also Coordinator at Cardio Metabolic Unit, CMU.

CMU is a research constellation driving innovative and implementable research and education, closely integrated with specialized health care. In line with its translational approach, CMU is linked to the Department of Medicine, Huddinge and Department of Laboratory Medicine at Campus Flemingsberg.

Articles

Article: ATHEROSCLEROSIS. 2024;394:117545
Modification of lipoprotein metabolism and function driving atherogenesis in diabetes
Luciani L; Pedrelli M; Parini P
Article: EPMA JOURNAL. 2024;15(2):149-162
Digital biomarkers: 3PM approach revolutionizing chronic disease management - EPMA 2024 position
Smokovski I; Steinle N; Behnke A; Bhaskar SMM; Grech G; Richter K; Niklewski G; Birkenbihl C; Parini P; Andrews RJ; Bauchner H; Golubnitschaja O
Article: GENOME BIOLOGY. 2024;25(1):104
Single Cell Atlas: a single-cell multi-omics human cell encyclopedia
Pan L; Parini P; Tremmel R; Loscalzo J; Lauschke V; Maron B; Paci P; Ernberg I; Tan NS; Liao Z; Yin W; Rengarajan S; Li X
Article: EPMA JOURNAL. 2024;15(1):1-23
The paradigm change from reactive medical services to 3PM in ischemic stroke: a holistic approach utilising tear fluid multi-omics, mitochondria as a vital biosensor and AI-based multi-professional data interpretation
Golubnitschaja O; Polivka Jr J; Potuznik P; Pesta M; Stetkarova I; Mazurakova A; Lackova L; Kubatka P; Kropp M; Thumann G; Erb C; Froehlich H; Wang W; Baban B; Kapalla M; Shapira N; Richter K; Karabatsiakis A; Smokovski I; Schmeel LC; Gkika E; Paul F; Parini P; Polivka J
Article: EUROPEAN HEART JOURNAL OPEN. 2024;4(2):oeae010
Relation among hypertriglyceridaemia, cardiometabolic disease, and hereditary factors-design and rationale of the Stockholm hyperTRIglyceridaemia REGister study.
Andersson DP; Littmann K; Kindborg G; Eklund D; Sejersen K; Yan J; Eriksson Hogling D; Parini P; Brinck J
Article: FRONTIERS IN PHYSIOLOGY. 2024;15:1371096
The nonvesicular sterol transporter Aster-C plays a minor role in whole body cholesterol balance
Banerjee R; Hohe RC; Cao S; Jung BM; Horak AJ; Ramachandiran I; Massey WJ; Varadharajan V; Zajczenko NI; Burrows AC; Dutta S; Goudarzi M; Mahen K; Carter A; Helsley RN; Gordon SM; Morton RE; Strauch C; Willard B; Gogonea CB; Gogonea V; Pedrelli M; Parini P; Brown JM
Article: SCIENCE ADVANCES. 2023;9(20):eadf2982
Mice with humanized livers reveal the role of hepatocyte clocks in rhythmic behavior
Delbes A-S; Quinones M; Gobet C; Castel J; Denis RGP; Berthelet J; Weger BD; Challet E; Charpagne A; Metairon S; Piccand J; Kraus M; Rohde BH; Bial J; Wilson EM; Vedin L-L; Minniti ME; Pedrelli M; Parini P; Gachon F; Luquet S
Article: REVIEWS IN ENDOCRINE & METABOLIC DISORDERS. 2022;23(5):919-930
Metabolic actions of the growth hormone-insulin growth factor-1 axis and its interaction with the central nervous system
Al-Massadi O; Parini P; Ferno J; Luquet S; Quinones M
Article: JOURNAL OF INTERNAL MEDICINE. 2022;292(2):296-307
Soat2 ties cholesterol metabolism to β-oxidation and glucose tolerance in male mice
Pramfalk C; Ahmed O; Pedrelli M; Minniti ME; Luquet S; Denis RG; Olin M; Hardfeldt J; Vedin L-L; Steffensen KR; Ryden M; Hodson L; Eriksson M; Parini P
Article: JOURNAL OF LIPID RESEARCH. 2022;63(7):100232
Plasma FA composition in familial LCAT deficiency indicates SOAT2-derived cholesteryl ester formation in humans
Pavanello C; Ossoli A; Strazzella A; Rise P; Veglia F; Lhomme M; Parini P; Calabresi L
Article: BIOFACTORS. 2022;48(3):707-717
HDL-mediated reduction of cholesterol content inhibits the proliferation of prostate cancer cells induced by LDL: Role of ABCA1 and proteasome inhibition
Ossoli A; Giorgio E; Cetti F; Ruscica M; Rabacchi C; Tarugi P; Parini P; Pedrelli M; Gomaraschi M
Article: ATHEROSCLEROSIS. 2022;349:175-182
Plasma Lipoprotein(a) measured in routine clinical care and the association with incident calcified aortic valve stenosis during a 14-year observational period
Wodaje T; Littmann K; Habel H; Bottai M; Back M; Parini P; Brinck J
Article: EUROPEAN JOURNAL OF PREVENTIVE CARDIOLOGY. 2022;28(18):2038-2047
Plasma lipoprotein(a) measured in the routine clinical care is associated to atherosclerotic cardiovascular disease during a 14-year follow-up
Littmann K; Hagstrom E; Habel H; Bottai M; Eriksson M; Parini P; Brinck J
Article: ATHEROSCLEROSIS. 2021;338:55-63
Lipid-lowering and anti-thrombotic therapy in patients with peripheral arterial disease European Atherosclerosis Society/European Society of Vascular Medicine Joint Statement
Belch JJF; Brodmann M; Baumgartner I; Binder CJ; Casula M; Heiss C; Kahan T; Parini P; Poredos P; Catapano AL; Tokgozoglu L
Article: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2021;22(18):9969
Sex Dimorphism of Nonalcoholic Fatty Liver Disease (NAFLD) in Pparg-Null Mice
Schiffrin M; Winkler C; Quignodon L; Naldi A; Trotzmuller M; Kofeler H; Henry H; Parini P; Desvergne B; Gilardi F
Article: AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY. 2021;321(3):G243-G251
Liver X receptor β regulates bile volume and the expression of aquaporins and cystic fibrosis transmembrane conductance regulator in the gallbladder
Sweed N; Kim H-J; Hultenby K; Barros R; Parini P; Sancisi V; Strandvik B; Gabbi C
Article: SOCIAL SCIENCE & MEDICINE. 2021;282:114145
It takes two to dance the VBHC tango: A multiple case study of the adoption of value-based strategies in Sweden and Brazil
Ramos P; Savage C; Thor J; Atun R; Carlsson KS; Makdisse M; Neto MC; Klajner S; Parini P; Mazzocato P
Article: JOURNAL OF LIPID RESEARCH. 2021;62:100065
Vasculoprotective properties of plasma lipoproteins from brown bears (Ursus arctos)
Pedrelli M; Parini P; Kindberg J; Arnemo JM; Bjorkhem I; Aasa U; Westerstahl M; Walentinsson A; Pavanello C; Turri M; Calabresi L; Oorni K; Camejo G; Frobert O; Hurt-Camejo E
Article: JCI INSIGHT. 2020;5(24):140483
Depletion of protein kinase STK25 ameliorates renal lipotoxicity and protects against diabetic kidney disease
Cansby E; Caputo M; Gao L; Kulkarni NM; Nerstedt A; Stahlman M; Boren J; Porosk R; Soomets U; Pedrelli M; Parini P; Marschall H-U; Nystrom J; Howell BW; Mahlapuu M
Article: HEPATOLOGY. 2020;72(2):656-670
Insights From Liver-Humanized Mice on Cholesterol Lipoprotein Metabolism and LXR-Agonist Pharmacodynamics in Humans
Minniti ME; Pedrelli M; Vedin L-L; Delbes A-S; Denis RGP; Oorni K; Sala C; Pirazzini C; Thiagarajan D; Nurmi HJ; Grompe M; Mills K; Garagnani P; Ellis ECS; Strom SC; Luquet SH; Wilson EM; Bial J; Steffensen KR; Parini P
Article: DIABETES CARE. 2020;43(8):1851-1858
The Association of Lipoprotein(a) Plasma Levels With Prevalence of Cardiovascular Disease and Metabolic Control Status in Patients With Type 1 Diabetes
Littmann K; Wodaje T; Alvarsson M; Bottai M; Eriksson M; Parini P; Brinck J
Article: BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS. 2020;1865(6):158659
Generation of new hepatocyte-like in vitro models better resembling human lipid metabolism
Pramfalk C; Jakobsson T; Verzijl CRC; Minniti ME; Obensa C; Ripamonti F; Olin M; Pedrelli M; Eriksson M; Parini P
Article: JOURNAL OF CLINICAL LIPIDOLOGY. 2020;14(1):77-87
Impact of proprotein convertase subtilisin/kexin type 9 inhibition with evolocumab on the postprandial responses of triglyceride-rich lipoproteins in type II diabetic subjects
Taskinen M-R; Bjornson E; Andersson L; Kahri J; Porthan K; Matikainen N; Soderlund S; Pietilainen K; Hakkarainen A; Lundbom N; Nilsson R; Stahlman M; Adiels M; Parini P; Packard C; Boren J
Article: MOLECULAR AND CELLULAR ENDOCRINOLOGY. 2020;499:110604
Diiodothyronines regulate metabolic homeostasis in primary human hepatocytes by modulating mTORC1 and mTORC2 activity
Gnocchi D; Ellis ECS; Johansson H; Eriksson M; Bruscalupi G; Steffensen KR; Parini P
Article: JOURNAL OF INTERNAL MEDICINE. 2019;286(6):660-675
Subclinical atherosclerosis and its progression are modulated by PLIN2 through a feed-forward loop between LXR and autophagy
Saliba-Gustafsson P; Pedrelli M; Gertow K; Werngren O; Janas V; Pourteymour S; Baldassarre D; Tremoli E; Veglia F; Rauramaa R; Smit AJ; Giral P; Kurl S; Pirro M; de Faire U; Humphries SE; Hamsten A; Goncalves I; Orho-Melander M; Franco-Cereceda A; Boren J; Eriksson P; Magne J; Parini P; Ehrenborg E; Sirtori CR; Castelnuovo S; Amato M; Frigerio B; Ravani A; Sansaro D; Tedesco C; Bovis F; Discacciati A; Ahl M; Blomgren G; Eriksson MJ; Fahlstadius P; Heinonen M; Nilson L; Cooper J; Acharya J; Huttunen K; Rauramaa E; Pekkarinen H; Penttila IM; Torronen J; van Gessel AI; van Roon AM; Teune GC; Kuipers WD; Bruin M; Nicolai A; Haarsma-Jorritsma P; Mulder DJ; Bilo HJG; Smeets GH; Beaudeux JL; Kahn JF; Carreau V; Kontush A; Karppi J; Nurmi T; Nyyssonen K; Salonen R; Tuomainen TP; Tuomainen J; Kauhanen J; Vaudo G; Alaeddin A; Siepi D; Lupattelli G; Schillaci G
Article: DIGESTIVE AND LIVER DISEASE. 2019;51(7):1016-1022
Genetic depletion of Soat2 diminishes hepatic steatosis via genes regulating de novo lipogenesis and by GLUT2 protein in female mice
Ahmed O; Pramfalk C; Pedrelli M; Olin M; Steffensen KR; Eriksson M; Parini P
Article: NATURE COMMUNICATIONS. 2019;10(1):1684
Hepatocyte-specific loss of GPS2 in mice reduces non-alcoholic steatohepatitis via activation of PPARα
Liang N; Damdimopoulos A; Goni S; Huang Z; Vedin L-L; Jakobsson T; Giudici M; Ahmed O; Pedrelli M; Barilla S; Alzaid F; Mendoza A; Schroder T; Kuiper R; Parini P; Hollenberg A; Lefebvre P; Francque S; Van Gaal L; Staels B; Venteclef N; Treuter E; Fan R
Article: BIOLOGY OF SEX DIFFERENCES. 2019;10(1):11
Sex-specific lipid molecular signatures in obesity-associated metabolic dysfunctions revealed by lipidomic characterization in ob/ob mouse
Gonzalez-Granillo M; Helguero LA; Alves E; Archer A; Savva C; Pedrelli M; Ahmed O; Li X; Domingues MR; Parini P; Gustafsson J-A; Korach-Andre M
Article: MOLECULAR AND CELLULAR ENDOCRINOLOGY. 2019;479:147-158
ERβ activation in obesity improves whole body metabolism via adipose tissue function and enhanced mitochondria biogenesis
Gonzalez-Granillo M; Savva C; Li X; Fitch M; Pedrelli M; Hellerstein M; Parini P; Korach-Andre M; Gustafsson J-A
Article: JOURNAL OF THE AMERICAN HEART ASSOCIATION. 2018;7(24):e009876
Ezetimibe in Combination With Simvastatin Reduces Remnant Cholesterol Without Affecting Biliary Lipid Concentrations in Gallstone Patients
Ahmed O; Littmann K; Gustafsson U; Pramfalk C; Oorni K; Larsson L; Minniti ME; Sahlin S; Camejo G; Parini P; Eriksson M
Article: ATHEROSCLEROSIS. 2018;275:246-255
Overexpression of transforming growth factor β induced factor homeobox 1 represses NPC1L1 and lowers markers of intestinal cholesterol absorption
Parini P; Melhuish TA; Wotton D; Larsson L; Ahmed O; Eriksson M; Pramfalk C
Article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2018;38(8):1723-1737
STK25 Regulates Cardiovascular Disease Progression in a Mouse Model of Hypercholesterolemia
Cansby E; Magnusson E; Nunez-Duran E; Amrutkar M; Pedrelli M; Parini P; Hoffmann J; Stahlman M; Howell BW; Marschall H-U; Boren J; Mahlapuu M
Article: DRUGS. 2017;77(15):1613-1621
Potential Role of Thyroid Receptor β Agonists in the Treatment of Hyperlipidemia
Jakobsson T; Vedin L-L; Parini P
Article: JOURNAL OF LIPID RESEARCH. 2017;58(2):420-432
The lipid droplet-associated protein perilipin 3 facilitates hepatitis C virus-driven hepatic steatosis
Ferguson D; Zhang J; Davis MA; Helsley RN; Vedin L-L; Lee RG; Crooke RM; Graham MJ; Allende DS; Parini P; Brown JM
Article: EUROPEAN JOURNAL OF CLINICAL INVESTIGATION. 2017;47(2):137-148
Does statins promote vascular calcification in chronic kidney disease?
Chen Z; Qureshi AR; Parini P; Hurt-Camejo E; Ripsweden J; Brismar TB; Barany P; Jaminon AM; Schurgers LJ; Heimburger O; Lindholm B; Stenvinkel P
Article: SCIENTIFIC REPORTS. 2016;6:36937
Intestinal PPARγ signalling is required for sympathetic nervous system activation in response to caloric restriction
Duszka K; Picard A; Ellero-Simatos S; Chen J; Defernez M; Paramalingam E; Pigram A; Vanoaica L; Canlet C; Parini P; Narbad A; Guillou H; Thorens B; Wahli W
Article: JOURNAL OF CONTROLLED RELEASE. 2016;241:57-67
Development of drug-loaded immunoliposomes for the selective targeting and elimination of rosetting Plasmodium falciparum-infected red blood cells
Moles E; Moll K; Ch'ng J-H; Parini P; Wahlgren M; Fernandez-Busquets X
Article: AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY. 2016;310(11):G952-G961
Changes in gluconeogenesis and intracellular lipid accumulation characterize uremic human hepatocytes ex vivo
Li M; Ellis E; Johansson H; Nowak G; Isaksson B; Gnocchi D; Parini P; Axelsson J
Article: BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY. 2016;118(6):499-502
Effect of Statin Treatment on Plasma 4β-Hydroxycholesterol Concentrations
Bjorkhem-Bergman L; Nylen H; Eriksson M; Parini P; Diczfalusy U
Article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2016;36(5):787-791
Impaired Cholesterol Efflux Capacity of High-Density Lipoprotein Isolated From Interstitial Fluid in Type 2 Diabetes Mellitus-Brief Report
Apro J; Tietge UJF; Dikkers A; Parini P; Angelin B; Rudling M
Article: BIOCHIMICA ET BIOPHYSICA ACTA: INTERNATIONAL JOURNAL OF BIOCHEMISTRY AND BIOPHYSICS. 2016;1861(1):51-59
Culturing of HepG2 cells with human serum improve their functionality and suitability in studies of lipid metabolism
Pramfalk C; Larsson L; Hardfeldt J; Eriksson M; Parini P
Article: JOURNAL OF LIPID RESEARCH. 2015;56(8):1633-1639
Levels of atherogenic lipoproteins are unexpectedly reduced in interstitial fluid from type 2 diabetes patients
Apro J; Parini P; Broijersen A; Angelin B; Rudling M
Article: JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY. 2015;82:186-193
RNA therapeutics inactivate PCSK9 by inducing a unique intracellular retention form
Rocha CSJ; Wiklander OPB; Larsson L; Moreno PMD; Parini P; Lundin KE; Smith CIE
Article: CELL REPORTS. 2015;10(3):326-338
The TMAO-Generating Enzyme Flavin Monooxygenase 3 Is a Central Regulator of Cholesterol Balance
Warrier M; Shih DM; Burrows AC; Ferguson D; Gromovsky AD; Brown AL; Marshall S; McDaniel A; Schugar RC; Wang Z; Sacks J; Rong X; Vallim TDA; Chou J; Ivanova PT; Myers DS; Brown HA; Lee RG; Crooke RM; Graham MJ; Liu X; Parini P; Tontonoz P; Lusis AJ; Hazen SL; Temel RE; Brown JM
Article: HEPATOLOGY. 2015;61(1):161-170
Prevention of Spontaneous Hepatocarcinogenesis in Farnesoid X Receptor-Null Mice by Intestinal-Specific Farnesoid X Receptor Reactivation
Degirolamo C; Modica S; Vacca M; Di Tullio G; Morgano A; D'Orazio A; Kannisto K; Parini P; Moschetta A
Article: ATHEROSCLEROSIS. 2014;237(2):544-554
The thyroid receptor β modulator GC-1 reduces atherosclerosis in ApoE deficient mice
Kannisto K; Rehnmark S; Slatis K; Webb P; Larsson L; Gafvels M; Eggertsen G; Parini P
Article: HEPATOLOGY. 2014;59(5):1791-1802
Estrogen Receptor Ligands Ameliorate Fatty Liver Through a Nonclassical Estrogen Receptor/Liver X Receptor Pathway in Mice
Han S-I; Komatsu Y; Murayama A; Steffensen KR; Nakagawa Y; Nakajima Y; Suzuki M; Oie S; Parini P; Vedin L-L; Kishimoto H; Shimano H; Gustafsson J-A; Yanagisawa J
Article: JOURNAL OF LIPID RESEARCH. 2014;55(4):709-717
TG-interacting factor 1 acts as a transcriptional repressor of sterol O-acyltransferase 2
Pramfalk C; Melhuish TA; Wotton D; Jiang Z-Y; Eriksson M; Parini P
Article: AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM. 2014;306(5):E494-E502
Skeletal muscle as a target of LXR agonist after long-term treatment: focus on lipid homeostasis
Archer A; Laurencikiene J; Ahmed O; Steffensen KR; Parini P; Gustafsson J-A; Korach-Andre M
Article: PLOS ONE. 2014;9(11):e113619
Cholesterol, Oxysterol, Triglyceride, and Coenzyme Q Homeostasis in ALS. Evidence against the Hypothesis That Elevated 27-Hydroxycholesterol Is a Pathogenic Factor
Wuolikainen A; Acimovic J; Loevgren-Sandblom A; Parini P; Andersen PM; Bjoerkhem I
Article: PLOS ONE. 2014;9(4):e93552
Hepatic ACAT2 Knock Down Increases ABCA1 and Modifies HDL Metabolism in Mice
Pedrelli M; Davoodpour P; Degirolamo C; Gomaraschi M; Graham M; Ossoli A; Larsson L; Calabresi L; Gustafsson J-A; Steffensen KR; Eriksson M; Parini P
Article: DRUG METABOLISM AND DISPOSITION. 2013;41(9):1610-1615
Atorvastatin Treatment Induces Uptake and Efflux Transporters in Human Liver
Bjorkhem-Bergman L; Bergstrom H; Johansson M; Parini P; Eriksson M; Rane A; Ekstrom L
Article: PLOS ONE. 2013;8(12):e78534
The Thyroid Receptor Modulator KB3495 Reduces Atherosclerosis Independently of Total Cholesterol in the Circulation in ApoE Deficient Mice
Mork L-M; Rehnmark S; Davoodpour P; Norata GD; Larsson L; Witt M-R; Malm J; Parini P
Article: PLOS ONE. 2013;8(11):e78550
Mice with Chimeric Livers Are an Improved Model for Human Lipoprotein Metabolism
Ellis ECS; Nauglers S; Parini P; Mork L-M; Jorns C; Zemack H; Sandblom AL; Bjorkhem I; Ericzon B-G; Wilson EM; Strom SC; Grompe M
Article: PLOS ONE. 2013;8(7):e68534
Is It Possible to Improve Memory Function by Upregulation of the Cholesterol 24S-Hydroxylase (CYP46A1) in the Brain?
Maioli S; Bavner A; Ali Z; Heverin M; Ismail M-A; Puerta E; Olin M; Saeed A; Shafaati M; Parini P; Cedazo-Minguez A; Bjorkhem I
Article: MOLECULAR ENDOCRINOLOGY. 2012;26(12):1980-1990
Fasting-Induced FGF21 Is Repressed by LXR Activation via Recruitment of an HDAC3 Corepressor Complex in Mice
Archer A; Venteclef N; Mode A; Pedrelli M; Gabbi C; Clement K; Parini P; Gustafsson J-A; Korach-Andre M
Article: JOURNAL OF INTERNAL MEDICINE. 2012;272(5):452-464
LXRβ activation increases intestinal cholesterol absorption, leading to an atherogenic lipoprotein profile
Hu X; Steffensen KR; Jiang Z-Y; Parini P; Gustafsson J-A; Gafvels M; Eggertsen G
Article: FASEB JOURNAL. 2012;26(8):3282-3291
SOCS2 deletion protects against hepatic steatosis but worsens insulin resistance in high-fat-diet-fed mice
Zadjali F; Santana-Farre R; Vesterlund M; Carow B; Mirecki-Garrido M; Hernandez-Hernandez I; Flodstrom-Tullberg M; Parini P; Rottenberg M; Norstedt G; Fernandez-Perez L; Flores-Morales A
Article: JOURNAL OF BONE AND MINERAL METABOLISM. 2012;30(2):202-207
Physical training increases osteoprotegerin in postmenopausal women
Bergstrom I; Parini P; Gustafsson SA; Andersson G; Brinck J
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2012;417(3):1046-1051
Statins inhibit expression of Thioredoxin reductase 1 in rat and human liver and reduce tumour development
Skogastierna C; Johansson M; Parini P; Eriksson M; Eriksson LC; Ekstrom L; Bjorkhem-Bergman L
Article: PLOS ONE. 2012;7(11):e48694
Increased Expression of the Very Low-Density Lipoprotein Receptor Mediates Lipid Accumulation in Clear-Cell Renal Cell Carcinoma
Sundelin JP; Stahlman M; Lundqvist A; Levin M; Parini P; Johansson ME; Boren J
Article: PLOS ONE. 2012;7(5):e37386
Influence of Neonatal Hypothyroidism on Hepatic Gene Expression and Lipid Metabolism in Adulthood
Santana-Farre R; Mirecki-Garrido M; Bocos C; Henriquez-Hernandez LA; Kahlon N; Herrera E; Norstedt G; Parini P; Flores-Morales A; Fernandez-Perez L
Article: JOURNAL OF INTERNAL MEDICINE. 2011;270(4):377-387
Enhanced production of 24S-hydroxycholesterol is not sufficient to drive liver X receptor target genes in vivo
Shafaati M; Olin M; Bavner A; Pettersson H; Rozell B; Meaney S; Parini P; Bjorkhem I
Article: AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM. 2011;301(1):E210-E222
Liver X receptors regulate de novo lipogenesis in a tissue-specific manner in C57BL/6 female mice
Korach-Andre M; Archer A; Gabbi C; Barros RP; Pedrelli M; Steffensen KR; Pettersson AT; Laurencikiene J; Parini P; Gustafsson J-A
Article: HEART SURGERY FORUM. 2011;14(3):E195-E197
Late Cardiac Tamponade by Chylous Pericardial Effusion after Coronary Artery Bypass Surgery: Case Report
Albage A; Eggertsen G; Parini P
Article: JOURNAL OF INTERNAL MEDICINE. 2011;269(3):333-339
Effects of high-dose statin on the human hepatic expression of genes involved in carbohydrate and triglyceride metabolism
Pramfalk C; Parini P; Gustafsson U; Sahlin S; Eriksson M
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2011;108(1):403-408
Both liver-X receptor (LXR) isoforms control energy expenditure by regulating Brown Adipose Tissue activity
Korach-Andre M; Archer A; Barros RP; Parini P; Gustafsson J-A
Article: NEPHROLOGY DIALYSIS TRANSPLANTATION. 2011;26(1):184-190
Prevalence and clinical implications of testosterone deficiency in men with end-stage renal disease
Carrero JJ; Qureshi AR; Nakashima A; Arver S; Parini P; Lindholm B; Barany P; Heimbuerger O; Stenvinkel P
Article: WORLD JOURNAL OF GASTROENTEROLOGY. 2010;16(47):5958-5964
Thyroid hormones and thyroid hormone receptors: Effects of thyromimetics on reverse cholesterol transport
Pedrelli M; Pramfalk C; Parini P
Article: JOURNAL OF LIPID RESEARCH. 2010;51(11):3289-3298
Abolished synthesis of cholic acid reduces atherosclerotic development in apolipoprotein E knockout mice
Slatis K; Gafvels M; Kannisto K; Ovchinnikova O; Paulsson-Berne G; Parini P; Jiang Z-Y; Eggertsen G
Article: PLOS ONE. 2010;5(9):e13087
Decreased Fat Storage by Lactobacillus Paracasei Is Associated with Increased Levels of Angiopoietin-Like 4 Protein (ANGPTL4)
Aronsson L; Huang Y; Parini P; Korach-Andre M; Hakansson J; Gustafsson J-A; Pettersson S; Arulampalam V; Rafter J
Article: CELL METABOLISM. 2010;12(2):187-193
Intestinal Specific LXR Activation Stimulates Reverse Cholesterol Transport and Protects from Atherosclerosis
Lo Sasso G; Murzilli S; Salvatore L; D'Ernco I; Petruzzelli M; Conca P; Jiang Z-Y; Calabresi L; Parini P; Moschetta A
Article: JOURNAL OF LIPID RESEARCH. 2010;51(6):1354-1362
HNF1α and SREBP2 are important regulators of NPC1L1 in human liver
Pramfalk C; Jiang Z-Y; Cai Q; Hu H; Zhang S-D; Han T-Q; Eriksson M; Parini P
Article: HEPATOLOGY. 2010;51(4):1334-1344
Down-Regulation of the LXR Transcriptome Provides the Requisite Cholesterol Levels to Proliferating Hepatocytes
Lo Sasso G; Celli N; Caboni M; Murzilli S; Salvatore L; Morgano A; Vacca M; Pagliani T; Parini P; Moschetta A
Article: ANTICANCER RESEARCH. 2010;30(4):1105-1112
Lovastatin Prevents Carcinogenesis in a Rat Model for Liver Cancer. Effects of Ubiquinone Supplementation
Bjorkhem-Bergman L; Acimovic J; Torndal U-B; Parini P; Eriksson LC
Article: GENES & DEVELOPMENT. 2010;24(4):381-395
GPS2-dependent corepressor/SUMO pathways govern anti-inflammatory actions of LRH-1 and LXRβ in the hepatic acute phase response
Venteclef N; Jakobsson T; Ehrlund A; Damdimopoulos A; Mikkonen L; Ellis E; Nilsson L-M; Parini P; Janne OA; Gustafsson J-A; Steffensen KR; Treuter E
Article: AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM. 2010;298(2):E167-E178
Separate and overlapping metabolic functions of LXRα and LXRβ in C57Bl/6 female mice
Korach-Andre M; Parini P; Larsson L; Arner A; Steffensen KR; Gustafsson J-A
Article: ATHEROSCLEROSIS. 2009;207(1):266-271
ACAT2 and human hepatic cholesterol metabolism: Identification of important gender-related differences in normolipidemic, non-obese Chinese patients
Parini P; Jiang Z-Y; Einarsson C; Eggertsen G; Zhang S-D; Rudel LL; Han T-Q; Eriksson M
Article: LIPIDS. 2009;44(11):1011-1027
Cocoa Butter and Safflower Oil Elicit Different Effects on Hepatic Gene Expression and Lipid Metabolism in Rats
Gustavsson C; Parini P; Ostojic J; Cheung L; Hu J; Zadjali F; Tahir F; Brismar K; Norstedt G; Tollet-Egnell P
Article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2009;29(8):1235-1241
Control of ACAT2 Liver Expression by HNF4α Lesson From MODY1 Patients
Pramfalk C; Karlsson E; Groop L; Rudel LL; Angelin B; Eriksson M; Parini P
Article: ATHEROSCLEROSIS. 2009;204(2):381-387
Hypercholesterolemia leads to elevated TGF-β1 activity and T helper 3-dependent autoimmune responses in atherosclerotic mice
Zhou X; Johnston TP; Johansson D; Parini P; Funa K; Svensson J; Hansson GK
Article: CIRCULATION RESEARCH. 2009;104(8):961-968
T Cell-Mediated Inflammation in Adipose Tissue Does Not Cause Insulin Resistance in Hyperlipidemic Mice
Sultan A; Strodthoff D; Robertson A-K; Paulsson-Berne G; Fauconnier J; Parini P; Ryden M; Thierry-Mieg N; Johansson ME; Chibalin AV; Zierath JR; Arner P; Hansson GK
Article: CARCINOGENESIS. 2009;30(4):575-579
The oxysterol receptor LXR inhibits proliferation of human breast cancer cells
Vedin L-L; Lewandowski SA; Parini P; Gustafsson J-A; Steffensen KR
Article: JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY. 2009;20(3):613-620
Low Serum Testosterone Increases Mortality Risk among Male Dialysis Patients
Carrero JJ; Qureshi AR; Parini P; Arver S; Lindholm B; Barany P; Heimburger O; Stenvinkel P
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2009;379(1):49-54
Increased NPC1L1 and ACAT2 expression in the jejunal mucosa from Chinese gallstone patients
Jiang Z-Y; Jiang C-Y; Wang L; Wang J-C; Zhang S-D; Einarsson C; Eriksson M; Han T-Q; Parini P; Eggertsen G
Article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2008;28(6):1200-1206
Cholesterol synthesis inhibition elicits an integrated molecular response in human livers including decreased ACAT2
Parini P; Gustafsson U; Davis MA; Larsson L; Einarsson C; Wilson M; Rudling M; Tomoda H; Omura S; Sahlin S; Angelin B; Rudel LL; Eriksson M
Article: PLOS ONE. 2008;3(3):e1713
Monomeric Tartrate Resistant Acid Phosphatase Induces Insulin Sensitive Obesity
Lang P; van Harmelen V; Ryden M; Kaaman M; Parini P; Carneheim C; Cassady AI; Hume DA; Andersson G; Arner P
Article: ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS. 2008;471(1):63-71
Hypocholesterolemic effects of fatty acid bile acid conjugates (FABACs) in mice
Leikin-Frenkel A; Parini P; Konikoff FM; Benthin L; Lelkin-Gobbi D; Goldiner I; Einarsson C; Gilat T
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2008;105(6):2094-2099
Liver X receptor β (LXRβ):: A link between β-sitosterol and amyotrophic lateral sclerosis-Parkinson's dementia
Kim H-J; Fan X; Gabbi C; Yakimchuk K; Parini P; Warner M; Gustafsson J-A
Article: JOURNAL OF LIPID RESEARCH. 2008;49(2):464-472
Increased expression of LXRα, ABCG5, ABCG8, and SR-BI in the liver from normolipidemic, nonobese Chinese gallstone patients
Jiang Z-Y; Parini P; Eggertsen G; Davis MA; Hu H; Suo G-J; Zhang S-D; Rudel LL; Han T-Q; Einarsson C
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2007;364(2):402-409
Cholesterol regulates ACAT2 gene expression and enzyme activity in human hepatoma cells
Pramfalk C; Angelin B; Eriksson M; Parini P
Article: CLINICAL LIPIDOLOGY. 2007;2(6):603-607
Targeting liver X receptor β:: a new therapeutic approach to prevent atherosclerosis?
Parini P; Gustafsson J-A
Article: MOLECULAR PHARMACOLOGY. 2007;72(4):947-955
Physiological differences between human and rat primary hepatocytes in response to liver X receptor activation by 3-[3-[N-(2-chloro-3-trifluoromethylbenzyl)-(2,2diphenylethyl)amino]propyloxy] phenylacetic acid hydrochloride (GW3965)
Kotokorpi P; Ellis E; Parini P; Nilsson L-M; Strom S; Steffensen KR; Gustafsson J-A; Mode A
Article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2007;27(10):2191-2197
Studies on the cholesterol-free mouse -: Strong activation of LXR-regulated hepatic genes when replacing cholesterol with desmosterol
Heverin M; Meaney S; Brafman A; Shafir M; Olin M; Shafaati M; von Bahr S; Larsson L; Loevgren-Sandblom A; Diczfalusy U; Parini P; Feinstein E; Bjoerkhem I
Article: AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM. 2007;293(3):E737-E742
Age-induced hypercholesterolemia in the rat relates to reduced elimination but not increased intestinal absorption of cholesterol
Gaelman C; Matasconi M; Persson L; Parini P; Angelin B; Rudling M
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2007;357(3):707-711
Bile acids and lipoprotein metabolism: Effects of cholestyramine and chenodeoxycholic acid on human hepatic mRNA expression
Nilsson L-M; Abrahamsson A; Sahlin S; Gustafsson U; Angelin B; Parini P; Einarsson C
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2006;348(1):176-182
Improved metabolic control by depletion of Liver X Receptors in mice
Schuster GU; Johansson L; Kietz S; Stulnig TM; Parini P; Gustafsson J-A
Article: EUROPEAN JOURNAL OF CLINICAL INVESTIGATION. 2006;36(2):98-104
Lipoprotein profiles in plasma and interstitial fluid analyzed with an automated gel-filtration system
Parini P; Johansson L; Bröijersén A; Angelin B; Rudling M
Article: JOURNAL OF LIPID RESEARCH. 2006;47(2):421-430
Studies on LXR- and FXR-mediated effects on cholesterol homeostasis in normal and cholic acid-depleted mice
Wang J; Einarsson C; Murphy C; Parini P; Björkhem I; Gåfvels M; Eggertsen G
Article: BIOCHIMICA ET BIOPHYSICA ACTA: INTERNATIONAL JOURNAL OF BIOCHEMISTRY AND BIOPHYSICS. 2005;1736(3):221-227
Pituitary control of cholesterol metabolism in normal and LDL receptor knock-out mice: Effects of hypophysectomy and growth hormone treatment
Matasconi M; Panini P; Angelin B; Rudling M
Article: JOURNAL OF LIPID RESEARCH. 2005;46(9):1868-1876
Control of ACAT2 liver expression by HNF1
Pramfalk C; Davis MA; Eriksson M; Rudel LL; Parini P
Article: BIOCHIMICA ET BIOPHYSICA ACTA: INTERNATIONAL JOURNAL OF BIOCHEMISTRY AND BIOPHYSICS. 2005;1735(3):167-175
Cholic acid as key regulator of cholesterol synthesis, intestinal absorption and hepatic storage in mice
Murphy C; Parini P; Wang J; Björkhem I; Eggertsen G; Gåfvels M
Article: JOURNAL OF LIPID RESEARCH. 2005;46(8):1633-1642
LXR deficiency and cholesterol feeding affect the expression and phenobarbital-mediated induction of cytochromes P450 in mouse liver
Gnerre C; Schuster GU; Roth A; Handschin C; Johansson L; Looser R; Parini P; Podvinec M; Robertsson K; Gustafsson J; Meyer UA
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2005;102(29):10297-10302
Selective thyroid receptor modulation by GC-1 reduces serum lipids and stimulates steps of reverse cholesterol transport in euthyroid mice
Johansson L; Rudling M; Scanlan TS; Lundåsen T; Webb P; Baxter J; Angelin B; Parini P
Article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2005;25(6):1112-1118
ACAT2 is a target for treatment of coronary heart disease associated with hypercholesterolemia
Rudel LL; Lee RG; Parini P
Article: CIRCULATION RESEARCH. 2005;96(4):427-434
Lesion development and response to immunization reveal a complex role for CD4 in atherosclerosis
Zhou XH; Robertson AKL; Rudling M; Parini P; Hansson GK
Article: CIRCULATION. 2004;110(14):2017-2023
ACAT2 is localized to Hepatocytes and is the major cholesterol-esterifying enzyme in human liver
Parini P; Davis M; Lada AT; Erickson SK; Wright TL; Gustafsson U; Sahlin S; Einarsson C; Eriksson M; Angelin B; Tomoda H; Omura S; Willingham MC; Rudel LL
Article: CIRCULATION RESEARCH. 2004;94(12):1579-1588
Angiogenesis inhibitor, TNP-470, prevents diet-induced and genetic obesity in mice
Bråkenhielm E; Cao RH; Gao BH; Angelin B; Cannon B; Parini P; Cao YH
Article: PHYSIOLOGICAL GENOMICS. 2004;16(2):261-267
Growth hormone-mediated alteration of fuel metabolism in the aged rat as determined from transcript profiles
Tollet-Egnell P; Parini P; Ståhlberg N; Lönnstedt I; Lee NH; Rudling M; Flores-Morales A; Norstedt G
Article: ATHEROSCLEROSIS SUPPLEMENTS. 2002;3(4):23-30
Reverse cholesterol transport in man: promotion of fecal steroid excretion by infusion of reconstituted HDL
Angelin B; Parini P; Eriksson M
Article: CIRCULATION. 2002;106(9):1147-1153
Accumulation of foam cells in liver X receptor-deficient mice
Schuster GU; Parini P; Wang L; Alberti S; Steffensen KR; Hansson GK; Angelin B; Gustafsson J
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2002;293(5):1333-1340
Different regulation of the LXRα promoter activity by isoforms of CCAAT/enhancer-binding proteins
Steffensen KR; Schuster GU; Parini P; Holter E; Sadek CM; Cassel T; Eskild W; Gustafsson J
Article: JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY. 2001;78(1):83-88
Estrogenic influence on the regulation of hepatic estrogen receptor-α and serum level of angiotensinogen in female rats
Stavréus-Evers A; Parini P; Freyschuss B; Elger W; Reddersen G; Sahlin L; Eriksson H
Article: JOURNAL OF CLINICAL INVESTIGATION. 2001;107(5):565-573
Hepatic cholesterol metabolism and resistance to dietary cholesterol in LXRβ-deficient mice
Alberti S; Schuster G; Parini P; Feltkamp D; Diczfalusy U; Rudling M; Angelin B; Björkhem I; Pettersson S; Gustafsson J
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2000;278(3):640-645
Obesity and disturbed lipoprotein profile in estrogen receptor-α-deficient male mice
Ohlsson C; Hellberg N; Parini P; Vidal O; Bohlooly M; Rudling M; Lindberg MK; Warner M; Angelin B; Gustafsson J
Article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2000;20(7):1817-1823
Biphasic effects of the natural estrogen 17β-estradiol on hepatic cholesterol metabolism in intact female rats
Parini P; Angelin B; Stavréus-Evers A; Freyschuss B; Eriksson H; Rudling M
Article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 1999;19(4):832-839
Cholesterol and lipoprotein metabolism in aging - Reversal of hypercholesterolemia by growth hormone treatment in old rats
Parini P; Angelin B; Rudling M
Article: AMERICAN JOURNAL OF PATHOLOGY. 1998;153(6):1923-1935
Lipoprotein receptors in acute myelogenous leukemia -: Failure to defect increased low-density lipoprotein (LDL) receptor numbers in cell membranes despite increased cellular LDL degradation
Rudling M; Gåfvels M; Parini P; Gahrton G; Angelin B
Article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 1997;17(9):1800-1805
Importance of estrogen receptors in hepatic LDL receptor regulation
Parini P; Angelin B; Rudling M
Article: JOURNAL OF CLINICAL INVESTIGATION. 1997;99(9):2239-2245
Growth hormone and bile acid synthesis - Key role for the activity of hepatic microsomal cholesterol 7 alpha-hydroxylase in the rat
Rudling M; Parini P; Angelin B
Article: ENDOCRINOLOGY. 1995;136(9):3767-3773
GROWTH-HORMONE SPECIFICALLY STIMULATES THE EXPRESSION OF LOW-DENSITY-LIPOPROTEIN RECEPTORS IN HUMAN HEPATOMA-CELLS
PARINI P; ANGELIN B; LOBIE PE; NORSTEDT G; RUDLING M
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All other publications

Editorial comment: ATHEROSCLEROSIS. 2024;397:118562
HDL, reverse cholesterol transport, and atherosclerosis: Unravelling the complexity or adding to the confusion?
Parini P
Review: AGEING RESEARCH REVIEWS. 2024;94:102194
Lipid droplets, autophagy, and ageing: A cell-specific tale
Maestri A; Garagnani P; Pedrelli M; Hagberg CE; Parini P; Ehrenborg E
Review: PROGRESS IN CARDIOVASCULAR DISEASES. 2023;79:2-11
Bempedoic acid in the management of lipid disorders and cardiovascular risk. 2023 position paper of the International Lipid Expert Panel (ILEP)
Banach M; Penson PE; Farnier M; Fras Z; Latkovskis G; Laufs U; Paneni F; Parini P; Pirro M; Reiner Z; Vrablik M; Escobar C
Review: VASA-EUROPEAN JOURNAL OF VASCULAR MEDICINE. 2021;50(6):401-411
Lipid-lowering and anti-thrombotic therapy in patients with peripheral arterial disease
Belch JJF; Brodmann M; Baumgartner I; Binder CJ; Casula M; Heiss C; Kahan T; Parini P; Poredos P; Catapano AL; Tokgozoglu L
Editorial comment: ATHEROSCLEROSIS. 2021;322:77-81
Taking action: European Atherosclerosis Society targets the United Nations Sustainable Development Goals 2030 agenda to fight atherosclerotic cardiovascular disease in Europe
Parini P; Frikke-Schmidt R; Tselepis AD; Moulin P; von Eckardstein A; Binder CJ; Catapano AL; Ray KK; Tokgozoglu L
Review: CLINICAL EPIGENETICS. 2021;13(1):66
Clinical epigenetics settings for cancer and cardiovascular diseases: real-life applications of network medicine at the bedside
Sarno F; Benincasa G; List M; Barabasi A-L; Baumbach J; Ciardiello F; Filetti S; Glass K; Loscalzo J; Marchese C; Maron BA; Paci P; Parini P; Petrillo E; Silverman EK; Verrienti A; Altucci L; Napoli C
Editorial comment: AMERICAN JOURNAL OF MEDICINE. 2020;133(9):e451-e454
The Network Medicine Imperative and the Need for an International Network Medicine Consortium
Parini P; Altucci L; Balligand J-L; Baumbach J; Ferdinandy P; Filetti S; Maron BA; Petrillo E; Silverman EK; Barabasi A-L; Loscalzo J
Editorial comment: NPJ SYSTEMS BIOLOGY AND APPLICATIONS. 2020;6(1):29
A global network for network medicine
Maron BA; Altucci L; Balligand J-L; Baumbach J; Ferdinandy P; Filetti S; Parini P; Petrillo E; Silverman EK; Barabasi A-L; Loscalzo J
Review: NATURE REVIEWS ENDOCRINOLOGY. 2018;14(10):576-590
Inflammaging: a new immune-metabolic viewpoint for age-related diseases
Franceschi C; Garagnani P; Parini P; Giuliani C; Santoro A
Editorial comment: JOURNAL OF LIPID RESEARCH. 2018;59(9):1551-1553
Hepatic thyroid hormone receptor β1 agonism: good for lipids, good for bile?
Dawson PA; Parini P
Review: JOURNAL OF INTERNAL MEDICINE. 2017;281(6):534-553
Can LDL cholesterol be too low? Possible risks of extremely low levels
Olsson AG; Angelin B; Assmann G; Binder CJ; Bjoerkhem I; Cedazo-Minguez A; Cohen J; von Eckardstein A; Farinaro E; Mueller-Wieland D; Parhofer KG; Parini P; Rosenson RS; Starup-Linde J; Tikkanen MJ; Yvan-Charvet L
Review: ACTA PHYSIOLOGICA. 2016;217(3):184-216
Emerging role of thyroid hormone metabolites
Gnocchi D; Steffensen KR; Bruscalupi G; Parini P
Review: BIOLOGY-BASEL. 2015;4(1):104-132
Lipids around the Clock: Focus on Circadian Rhythms and Lipid Metabolism.
Gnocchi D; Pedrelli M; Hurt-Camejo E; Parini P
Published conference paper: BIOCHIMICA ET BIOPHYSICA ACTA: INTERNATIONAL JOURNAL OF BIOCHEMISTRY AND BIOPHYSICS. 2015;1851(1):9-12
Role of TG-interacting factor (Tgif) in lipid metabolism
Pramfalk C; Eriksson M; Parini P
Published conference paper: TRANSPLANTATION PROCEEDINGS. 2013;45(5):1780-1786
Serum Apolipoprotein E as a Marker to Monitor Graft Function After Hepatocyte Transplantation in a Clinically Relevant Mouse Model
Jorns C; Takahashi T; Callaghan E; Zemack H; Larsson L; Nowak G; Parini P; Ericzon B-G; Ellis E
Review: EUROPEAN JOURNAL OF LIPID SCIENCE AND TECHNOLOGY. 2012;114(6):624-633
Cholesteryl esters and ACAT
Pramfalk C; Eriksson M; Parini P
Review: BIOCHIMICA ET BIOPHYSICA ACTA: INTERNATIONAL JOURNAL OF BIOCHEMISTRY AND BIOPHYSICS. 2011;1812(8):929-937
Role of thyroid receptor β in lipid metabolism
Pramfalk C; Pedrelli M; Parini P
Review: CURRENT OPINION IN LIPIDOLOGY. 2011;22(3):225-230
Hepatic Niemann-Pick C1-like 1
Pramfalk C; Jiang Z-Y; Parini P
Editorial comment: ATHEROSCLEROSIS. 2011;215(1):249-255
Report of the 33rd Annual Conference of the European Lipoprotein Club, Tutzing, 6-9 September 2010
Bernini F; Fisher R; Freeman D; Groen A; Kalopissis A; Malle E; Mulder M; Niemeier A; Parini P; Hansen AT; von Eckardstein A
Meeting abstract: ATHEROSCLEROSIS SUPPLEMENTS. 2010;11(2):64
EFFECTS OF HIGH DOSE STATIN ON THE HUMAN HEPATIC EXPRESSION OF GENES INVOLVED IN CARBOHYDRATE AND TRIGLYCERIDE METABOLISM
Pramfalk C; Parini P; Gustafsson U; Sahlin S; Eriksson M
Letter: JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION. 2009;302(3):255
Carotid Atherosclerosis Progression and ACAT Inhibition
Parini P; Eriksson M; Rudel LL
Meeting abstract: ATHEROSCLEROSIS SUPPLEMENTS. 2007;8(1):24
ACAT2 and human hepatic cholesterol mkiabolism: Identification of important gender-related differences
Jiang ZY; Parini P; Einarsson C; Eggertsen G; Davis MA; Wang L; Zhang SD; Rudel LL; Han TQ; Ericsson M
Corrigendum: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2006;348(1):326
Obesity and disturbed lipoprotein profile in estrogen receptor-α-deficient male mice (vol 278, pg 640, 2000)
Ohlsson C; Hellberg N; Parini P; Vidal O; Bohlooly-Y M; Rudling M; Lindberg MK; Warner M; Angelin B; Gustafsson J-A
Editorial comment: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2003;23(3):374-375
Is there a need for cholesteryl ester transfer protein inhibition?
Parini P; Rudel LL
Published conference paper: GROWTH HORMONE & IGF RESEARCH. 1999;9:1-7
Effects of growth hormone on hepatic cholesterol metabolism. Lessons from studies in rats and humans
Rudling M; Parini P; Angelin B
Thesis / dissertation: 1999
Hormonal regulation of hepatic cholesterol and lipoprotein metabolism : effects of estrogen and growth hormone
Parini, Paolo
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Employments

Professor/Senior Physician, Department of Medicine, Huddinge, Karolinska Institutet, 2015-
Professor/Senior Physician, Department of Laboratory Medicine, Karolinska Institutet, 2012-

Degrees and Education

Docent, Karolinska Institutet, 2007
Doctor Of Philosophy, Department of Medicine, Huddinge, Karolinska Institutet, 1999

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