Nina Heldring

Publications
CV
Public outreach and news

Articles

Article: STEM CELLS TRANSLATIONAL MEDICINE. 2020;9(10):1190-1202
Treatment of chronicGvHDwith mesenchymal stromal cells induces durable responses: A phaseIIstudy
Boberg E; von Bahr L; Afram G; Lindstrom C; Ljungman P; Heldring N; Petzelbauer P; Legert KG; Kadri N; Le Blanc K
Article: GYNECOLOGIC ONCOLOGY. 2020;156(2):293-300
A randomized phase III trial in patients with recurrent platinum sensitive ovarian cancer comparing efficacy and safety of paclitaxel micellar and Cremophor EL-paclitaxel.
Vergote I; Bergfeldt K; Franquet A; Lisyanskaya AS; Bjermo H; Heldring N; Buyse M; Brize A
Article: ADVANCES IN THERAPY. 2019;36(10):2825-2837
Pharmacokinetics of Total and Unbound Paclitaxel After Administration of Paclitaxel Micellar or Nab-Paclitaxel: An Open, Randomized, Cross-Over, Explorative Study in Breast Cancer Patients.
Borgå O; Lilienberg E; Bjermo H; Hansson F; Heldring N; Dediu R
Article: ADVANCES IN THERAPY. 2019;36(5):1150-1163
Maximum Tolerated Dose and Pharmacokinetics of Paclitaxel Micellar in Patients with Recurrent Malignant Solid Tumours: A Dose-Escalation Study.
Borgå O; Henriksson R; Bjermo H; Lilienberg E; Heldring N; Loman N
Article: FRONTIERS IN IMMUNOLOGY. 2019;10:2249
The Complement System Is Essential for the Phagocytosis of Mesenchymal Stromal Cells by Monocytes
Gavin C; Meinke S; Heldring N; Heck KA; Achour A; Iacobaeus E; Le Blanc K; Kadri N; Hoglund P
Article: STEM CELLS. 2017;35(3):766-776
Mesenchymal Stromal Cell Secretion of Programmed Death-1 Ligands Regulates T Cell Mediated Immunosuppression
Davies LC; Heldring N; Kadri N; Le Blanc K
Article: STEM CELLS TRANSLATIONAL MEDICINE. 2016;5(11):1485-1495
Type 1 Diabetes Mellitus Donor Mesenchymal. Stromal Cells Exhibit Comparable Potency to Healthy Controls In Vitro
Davies LC; Alm JJ; Heldring N; Moll G; Gavin C; Batsis I; Qian H; Sigvardsson M; Nilsson B; Kyllonen LE; Salmela KT; Carlsson P-O; Korsgren O; Le Blanc K
Article: STEM CELLS TRANSLATIONAL MEDICINE. 2015;4(10):1199-1213
In Vivo Effects of Mesenchymal Stromal Cells in Two Patients With Severe Acute Respiratory Distress Syndrome
Simonson OE; Mougiakakos D; Heldring N; Bassi G; Johansson HJ; Dalen M; Jitschin R; Rodin S; Corbascio M; El Andaloussi S; Wiklander OPB; Nordin JZ; Skog J; Romain C; Koestler T; Hellgren-Johansson L; Schiller P; Joachimsson P-O; Haegglund H; Mattsson M; Lentio J; Faridani OR; Sandberg R; Korsgren O; Krampera M; Weiss DJ; Grinnemo K-H; Le Blanc K
Article: CELL DEATH & DISEASE. 2015;6(6):e1793
Tet3 mediates stable glucocorticoid-induced alterations in DNA methylation and Dnmt3a/Dkk1 expression in neural progenitors
Bose R; Spulber S; Kilian P; Heldring N; Lonnerberg P; Johnsson A; Conti M; Hermanson O; Ceccatelli S
Article: JOURNAL OF EXTRACELLULAR VESICLES. 2015;4:26316
Extracellular vesicle in vivo biodistribution is determined by cell source, route of administration and targeting
Wiklander OPB; Nordin JZ; O'Loughlin A; Gustafsson Y; Corso G; Maeger I; Vader P; Lee Y; Sork H; Seow Y; Heldring N; Alvarez-Erviti L; Smith CIE; Le Blanc K; Macchiarini P; Jungebluth P; Wood MJA; EL Andaloussi S
Article: STEM CELLS. 2014;32(9):2430-2442
Do Cryopreserved Mesenchymal Stromal Cells Display Impaired Immunomodulatory and Therapeutic Properties?
Moll G; Alm JJ; Davies LC; von Bahr L; Heldring N; Stenbeck-Funke L; Hamad OA; Hinsch R; Ignatowicz L; Locke M; Lonnies H; Lambris JD; Teramura Y; Nilsson-Ekdahl K; Nilsson B; Le Blanc K
Article: NEURO-ONCOLOGY. 2014;16(2):241-249
NCoR controls glioblastoma tumor cell characteristics
Heldring N; Nyman U; Lonnerberg P; Onnestam S; Herland A; Holmberg J; Hermanson O
Article: PLOS ONE. 2014;9(1):e85040
Do ABO Blood Group Antigens Hamper the Therapeutic Efficacy of Mesenchymal Stromal Cells?
Moll G; Hult A; von Bahr L; Alm JJ; Heldring N; Hamad OA; Stenbeck-Funke L; Larsson S; Teramura Y; Roelofs H; Nilsson B; Fibbe WE; Olsson ML; Le Blanc K
Article: NATURE. 2013;500(7463):468-471
The histone H4 lysine 16 acetyltransferase hMOF regulates the outcome of autophagy
Fullgrabe J; Lynch-Day MA; Heldring N; Li W; Struijk RB; Ma Q; Hermanson O; Rosenfeld MG; Klionsky DJ; Joseph B
Article: JOURNAL OF MOLECULAR ENDOCRINOLOGY. 2012;49(3):277-287
Estrogen receptor-α, RBCK1, and protein kinase C β 1 cooperate to regulate estrogen receptor-α gene expression
Sheppard NG; Heldring N; Dahlman-Wright K
Article: CNS & NEUROLOGICAL DISORDERS-DRUG TARGETS. 2012;11(7):884-892
Pitx2 Expression Promotes p21 Expression and Cell Cycle Exit in Neural Stem Cells
Heldring N; Joseph B; Hermanson O; Kioussi C
Article: MOLECULAR ENDOCRINOLOGY. 2012;26(5):736-747
Estrogen regulates JNK1 genomic localization to control gene expression and cell growth in breast cancer cells.
Sun M; Isaacs GD; Hah N; Heldring N; Fogarty EA; Kraus WL
Article: MOLECULAR ENDOCRINOLOGY. 2011;25(4):564-574
Multiple sequence-specific DNA-binding proteins mediate estrogen receptor signaling through a tethering pathway.
Heldring N; Isaacs GD; Diehl AG; Sun M; Cheung E; Ranish JA; Kraus WL
Article: PLOS ONE. 2010;5(12):e15594
Fatty Acids Derived from Royal Jelly Are Modulators of Estrogen Receptor Functions
Moutsatsou P; Papoutsi Z; Kassi E; Heldring N; Zhao C; Tsiapara A; Melliou E; Chrousos GP; Chinou I; Karshikoff A; Nilsson L; Dahlman-Wright K
Article: DEVELOPMENTAL BIOLOGY. 2010;348(2):153-166
Notch induces cyclin-D1-dependent proliferation during a specific temporal window of neural differentiation in ES cells
Das D; Lanner F; Main H; Andersson ER; Bergmann O; Sahlgren C; Heldring N; Hermanson O; Hansson EM; Lendahl U
Article: BIOCHEMICAL JOURNAL. 2007;406(2):343-353
Co-planar 3,3′,4,4′5-pentachlorinated biphenyl and non-co-planar 2,2′,4,6,6′-pentachlorinated biphenyl differentially induce recruitment of oestrogen receptor α to aryl hydrocarbon receptor target genes
Matthews J; Wihlen B; Heldring N; MacPherson L; Helguero L; Treuter E; Haldosen L-A; Gustafsson J-A
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2007;282(14):10449-10455
Structural insights into corepressor recognition by antagonist-bound estrogen receptors
Heldring N; Pawson T; McDonnell D; Treuter E; Gustafsson J-A; Pike ACW
Article: JOURNAL OF MEDICINAL CHEMISTRY. 2006;49(25):7357-7365
Subtle side-chain modifications of the hop phytoestrogen 8-prenylnaringenin result in distinct agonist/antagonist activity profiles for estrogen receptors α and β
Roelens F; Heldring N; Dhooge W; Bengtsson M; Comhaire F; Gustafsson J-A; Treuter E; De Keukeleire D
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2005;102(10):3593-3598
Delineation of a unique protein-protein interaction site on the surface of the estrogen receptor
Kong EH; Heldring N; Gustafsson J; Treuter E; Hubbard RE; Pike ACW
Article: MOLECULAR AND CELLULAR BIOLOGY. 2004;24(8):3445-3459
Identification of tamoxifen-induced coregulator interaction surfaces within the ligand-binding domain of estrogen receptors
Heldring N; Nilsson M; Buehrer B; Treuter E; Gustafsson J
Show more

All other publications

Corrigendum: NATURE. 2017;543(7647):742
Corrigendum: The histone H4 lysine 16 acetyltransferase hMOF regulates the outcome of autophagy.
Füllgrabe J; Lynch-Day MA; Heldring N; Li W; Struijk RB; Ma Q; Hermanson O; Rosenfeld MG; Klionsky DJ; Joseph B
Corrigendum: STEM CELLS TRANSLATIONAL MEDICINE. 2016;5(6):845
In Vivo Effects of Mesenchymal Stromal Cells in Two Patients With Severe Acute Respiratory Distress Syndrome (vol 4, pg 1199, 2015)
Simonson OE; Mougiakakos D; Heldring N; Bassi G; Johansson HJ; Dalen M; Jitschin R; Rodin S; Corbascio M; El Andaloussi S; Wiklander OPB; Nordin JZ; Skog J; Romain C; Koestler T; Hellgren-Johansson L; Schiller P; Joachimsson P-O; Hagglund H; Mattsson M; Lehtio J; Faridani OR; Sandberg R; Korsgren O; Krampera M; Weiss DJ; Grinnemo K-H; Le Blanc K
Review: HUMAN GENE THERAPY. 2015;26(8):506-517
Therapeutic Potential of Multipotent Mesenchymal Stromal Cells and Their Extracellular Vesicles
Heldring N; Mager I; Wood MJA; Le Blanc K; Andaloussi SEL
Review: AUTOPHAGY. 2014;10(4):556-561
Cracking the survival code Autophagy-related histone modifications
Fullgrabe J; Heldring N; Hermanson O; Joseph B
Review: BIOCHIMICA ET BIOPHYSICA ACTA: INTERNATIONAL JOURNAL OF BIOCHEMISTRY AND BIOPHYSICS. 2013;1830(2):2354-2360
Like a rolling histone: Epigenetic regulation of neural stem cells and brain development by factors controlling histone acetylation and methylation
Lilja T; Heldring N; Hermanson O
Review: PHYSIOLOGICAL REVIEWS. 2007;87(3):905-931
Estrogen receptors:: How do they signal and what are their targets
Heldring N; Pike A; Andersson S; Matthews J; Cheng G; Hartman J; Tujague M; Stroem A; Treuter E; Warner M; Gustafsson J-A
Doctoral thesis: 2006
Molecular basis of estrogen receptor antagonism
Heldring N
Published conference paper: TOXICOLOGY IN VITRO. 1998;12(5):557-560
Neurite degeneration in differentiated human neuroblastoma cells.
Nordin-Andersson M; Forsby A; Heldring N; Dejongh J; Kjellstrand P; Walum E

Employments

Affiliated to Research, Department of Laboratory Medicine, Karolinska Institutet, 2025-2028

Degrees and Education

Doctor Of Philosophy, Department of Biosciences and Nutrition, Karolinska Institutet, 2006

Articles

All other publications

Employments

Degrees and Education

News from KI

Events from KI