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About me

Resident in Paediatrics

Postdoctoral research fellow


MD 2012, Heidelberg, Germany

Dr. med. 2015, Heidelberg, Germany

Research description

Aetiology of Langerhans Cell Histiocytosis

Translational paediatric oncology and chemotherapy

Nucleotide metabolism

HIV infection and inflammation

Publications (selection)

Nucleobase and Nucleoside Analogues: Resistance and Re-Sensitisation at the Level of Pharmacokinetics, Pharmacodynamics and Metabolism.
Tsesmetzis N, Paulin C, Rudd S, Herold N
Cancers (Basel) 2018 Jul;10(7):

Effects of Inner Nuclear Membrane Proteins SUN1/UNC-84A and SUN2/UNC-84B on the Early Steps of HIV-1 Infection.
Schaller T, Bulli L, Pollpeter D, Betancor G, Kutzner J, Apolonia L, et al
J. Virol. 2017 10;91(19):

With me or against me: Tumor suppressor and drug resistance activities of SAMHD1.
Herold N, Rudd S, Sanjiv K, Kutzner J, Myrberg I, Paulin C, et al
Exp. Hematol. 2017 08;52():32-39

SAMHD1 protects cancer cells from various nucleoside-based antimetabolites.
Herold N, Rudd S, Sanjiv K, Kutzner J, Bladh J, Paulin C, et al
Cell Cycle 2017 Jun;16(11):1029-1038

Improved Local Control by Extensive Surgery in High-Risk Neuroblastoma May Be Dependent on Adjuvant Radiotherapy.
Stenman J, Herold N, Svensson P, Kogner P
J. Clin. Oncol. 2017 Jun;35(17):1965-1966

SAMHD1 is a barrier to antimetabolite-based cancer therapies.
Rudd S, Schaller T, Herold N
Mol Cell Oncol 2017 ;4(2):e1287554

Targeting SAMHD1 with the Vpx protein to improve cytarabine therapy for hematological malignancies.
Herold N, Rudd S, Ljungblad L, Sanjiv K, Myrberg I, Paulin C, et al
Nat. Med. 2017 Feb;23(2):256-263

Complex Interplay between HIV-1 Capsid and MX2-Independent Alpha Interferon-Induced Antiviral Factors.
Bulli L, Apolonia L, Kutzner J, Pollpeter D, Goujon C, Herold N, et al
J. Virol. 2016 08;90(16):7469-7480

The Early Bird Catches the Worm--Can Evolution Teach us Lessons in Fighting HIV?
Schaller T, Herold N
Curr. HIV Res. 2016 ;14(3):183-210

HIV-1 entry in SupT1-R5, CEM-ss, and primary CD4+ T cells occurs at the plasma membrane and does not require endocytosis.
Herold N, Anders-Ößwein M, Glass B, Eckhardt M, Müller B, Kräusslich H
J. Virol. 2014 Dec;88(24):13956-70

Teaching portfolio

Main supervisor PhD

Main supervisor MD research project

Academic honours, awards and prizes

NOPHO prize 2016, Stockholm, Sweden

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