Nele Brusselaers
About me
Nele is a medical doctor and epidemiologist, specialised in clinical- and pharmaco-epidemiology. She is a senior researcher and associate professor, and has worked at Karolinska Institutet since 2012.
- Nele combines this with a position as Professor in Pharmaco-epidemiology at the Global Health Institute, at the University of Antwerp
- in Belgium (since end 2020).
- She has a broad interest and experience in different clinical topics
- yet her current main focus is on long-term effects of commonly prescribed drugs on long-term health and the microbiome, with a focus on women's health, early life, cancer and infections. She has extensive experience in evidence synthesis methodologies (systematic reviews, meta-analyses etc. ), the Swedish Health Registries and various clinical and microbiome cohorts.
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Graduated PhD students:
As main supervisor:- Eva Doorakkers (Karolinska Institutet, 2019)
- Sam Van Slycke (Ghent University, 2020)
- Robin Willaert (Ghent Universtiy, 2021)
- Johanna Simin (Karolinska Institutet, 2021)
- Qing Liu (Karolinska Institutet, 2023)
As co-supervisor:
- John Maret.Ouda (Karolinska Institutet, 2018)
- Laurent Thierens (Ghent University, 2020)
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Awarded research funding as prinicipal investigator:
- SFO: Strategic Funding in Epidemiology (Karolinska Institutet): Young Scholar Grant (2014)
- Julin funding (2014)
- Bengt Ihres Fond (Svenska Läkaresällskapet) (2014, 2017, 2018)
- KI fonder (2014-2019)
- Svenska Läkaresällskapet (2015, 2018)
- KID funding: Karolinska Insitutet delfinansiering för nya doktorander
- (2015)
- Shizu Matsurais foundation (2017)
- Gastroenterolgisk forskningsfond (2017, 2018)
- Vetenskapsrådet (2020)
- Vetenskapsrådet (2023)
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Awarded research funding as co-applicant
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- KID funding: Karolinska Insitutet delfinansiering för nya doktorander
(2014) - SIMSAM (Swedish Initiative for Research on Microdata in the Social and
Medical Sciences) (2014-2018) - Alzheimerfonden (2018)
- KI Stifeltsen (2018)
- Comision Nacional de Investigacion Cientifica y Technolica (CONICYT)
(2018) - Romina Fornes - postdoc - Kronprinsessan Lovisas Förening För Barnasjukvård /Stifelsen Axel
- Tielmans (2019)
- ALF (2020)
Awards:- Best European Abstract - European Burn Association (EBA- 2009)
- Investigators award at the Congress of the Belgian Society of Internal Medicine (2010)
- Best abstract - European Society of Intensive Care Medicine (ESICM – 2010)
- Best abstract/4th best oral presentation (EBA - 2011).
- Selected as representative from KI to attend the Global Young Scientist Summit in Singapore (2014)
- KID funding: Karolinska Insitutet delfinansiering för nya doktorander
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Education/Career:
- Master in Medicine (MD), Ghent University (Belgium), 2008.
- PhD in Medical Sciences, Thesis: "Severe burn injury: Some determinants of epidemiological and surgical outcomes, Ghent University, Belgium, 2010.
- Master in Hospital Hygiene and Infection Control, Ghent University, (Belgium), 2010.
- Master in Epidemiology, London School of Hygiene and Tropical Medicine, (United Kingdom), 2015.
- Docent in Clinical Epidemiology, Karolinska Institutet, 2015.
- First post-doc: Dept of Internal medicine and Infectious diseases, Ghent,
- University, Belgium (2010-2012)
* Second post-doc: Upper-gastrointestinal surgery, Dept of Molecular
medicine and Surgery, Karolinska Insitutet (2012-2016) - Associate Professor / Senior Researcher
- (2016-2024) - Centre for Translational Microbiome Research, Dept. Microbiology, Tumour and Cellbiology, Karolinska Institutet
- Associate Professor / Senior Researcher - Dept of Women's and Children's Health,
- Karolinska Institutet (2024-current)
Research
I am the principal investigator of 5 large cohorts:
- Chemoprevention of cancer cohort (aim: to assess the impact of commonly prescribed drugs on the development of cancer)
- The Swedish Maternal Microbiome (SweMaMi) project (aim: to assess how the microbiome affects pregnancy outcomes and the health of the offspring) www.swemami.se
- Medication and the Maternal Microbiome (MediMami) project (aim: to assess the impact of commonly prescribed drugs during pregnancy, through potential microbiome alterations)
- PCOS (Polycystic Ovary syndrome) project (aim: to assess the effects on health in the offspring of mothers with PCOS)
- CDI project: /Clostridioides difficile/ infection [CDI], recurrence and mortality in Sweden: risk profiles, prescription drugs and burden.
Teaching
Course organiser:
- How to conduct systematic reviews and meta-analyses (KI PhD course 2790),
2014-2020
- Study design in clinical research (KI PhD course 1794), 2013-2015-
Undergraduate and postgraduate teaching at Karolinska Institutet, Antwerp University and Ghent University: including study design, systematic reviews and meta-analyses, pharmaco-epidemiology, cancer epidemiology, microbiome-epidemiology and other basic and advanced topics within
epidemiology and clinical research.
Articles
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Article: ACTA CHIRURGICA BELGICA. 2024;:1-6
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Article: CELL HOST & MICROBE. 2024;32(8):1235-1247
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Article: ACTA OBSTETRICIA ET GYNECOLOGICA SCANDINAVICA. 2024;103(8):1596-1605
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Article: BMC INFECTIOUS DISEASES. 2024;24(1):746
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Article: BMJ OPEN. 2024;14(7):e079591
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Article: UPDATES IN SURGERY. 2024;:1-9
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Article: VIROLOGY JOURNAL. 2024;21(1):119
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Article: BMC INFECTIOUS DISEASES. 2024;24(1):468
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Article: INFECTION. 2024;52(2):649-660
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Article: JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY. 2024;79(3):608-616
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Article: SCIENTIFIC REPORTS. 2024;14(1):4845
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Article: WORLD JOURNAL OF SURGERY. 2024;48(2):386-392
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Article: CLINICAL MICROBIOLOGY AND INFECTION. 2023;29(11):1424-1430
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Article: BJS OPEN. 2023;7(6):zrad124
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Article: BMC INFECTIOUS DISEASES. 2023;23(1):744
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Article: AIDS RESEARCH AND THERAPY. 2023;20(1):65
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Article: ACTA CHIRURGICA BELGICA. 2023;123(5):525-534
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Journal article: AMERICAN JOURNAL OF PREVENTIVE CARDIOLOGY. 2023;15:100532
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Article: COMMUNICATIONS MEDICINE. 2023;3(1):107
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Article: LANGENBECKS ARCHIVES OF SURGERY. 2023;408(1):254
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Journal article: HUMAN REPRODUCTION. 2023;38(Supplement_1)
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Article: MICROBIOLOGY SPECTRUM. 2023;11(3):e0506622-e05022
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Article: DIGESTIVE DISEASES AND SCIENCES. 2023;68(6):2252-2263
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Article: OPEN FORUM INFECTIOUS DISEASES. 2023;10(6):ofad241
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Article: CELL REPORTS MEDICINE. 2023;4(5):101035
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Journal article: BRITISH JOURNAL OF SURGERY. 2023;110(Supplement_2):znad080.007
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Article: AIDS RESEARCH AND THERAPY. 2023;20(1):15
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Article: BMC PREGNANCY AND CHILDBIRTH. 2023;23(1):153
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Article: COMMUNICATIONS BIOLOGY. 2023;6(1):20
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Article: BMC MEDICINE. 2022;20(1):492
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Article: GUT PATHOGENS. 2022;14(1):47
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Journal article: DIGESTIVE MEDICINE RESEARCH. 2022;0(0):0
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Article: LANGENBECKS ARCHIVES OF SURGERY. 2022;407(7):3045-3055
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Article: WORLD JOURNAL OF SURGERY. 2022;46(11):2678-2686
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Article: JOURNAL OF GLOBAL HEALTH. 2022;12:05017
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Article: SCIENTIFIC REPORTS. 2022;12(1):7926
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Journal article: ENDOCRINE ABSTRACTS. 2022
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Article: ACTA ONCOLOGICA. 2022;61(5):632-640
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Article: JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY. 2022;77(5):1461-1467
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Article: CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION. 2022;31(4):804-810
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Article: PATHOGENS. 2022;11(4):396
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Article: PEDIATRIC RESEARCH. 2022;91(4):937-946
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Article: REPRODUCTIVE BIOLOGY AND ENDOCRINOLOGY. 2022;20(1):30
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Article: ENDOCRINE-RELATED CANCER. 2022;29(3):163-173
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Article: HUMANITIES & SOCIAL SCIENCES COMMUNICATIONS. 2022;9(1):91
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Article: ANNALS OF SURGERY. 2021;274(6):E535-E540
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Article: PATHOGENS. 2021;10(11):1451
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Article: HEPATOLOGY. 2021;74(4):2021-2031
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Article: NEOPLASIA. 2021;23(10):1059-1068
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Article: BRITISH JOURNAL OF CANCER. 2021;125(6):893-900
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Article: UPDATES IN SURGERY. 2021;73(4):1449-1458
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Article: ACTA ONCOLOGICA. 2021;60(7):881-887
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Article: ALIMENTARY PHARMACOLOGY & THERAPEUTICS. 2021;53(11):1216-1225
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Article: ACTA CHIRURGICA BELGICA. 2021;121(3):178-183
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Article: INTERNATIONAL JOURNAL OF SURGERY. 2021;88:105922
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Article: PEDIATRIC RESEARCH. 2021;89(3):604-612
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Journal article: EUROPEAN JOURNAL OF MEDICAL CASE REPORTS. 2021;:325-329
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Article: BRITISH JOURNAL OF CANCER. 2020;123(12):1825-1832
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Article: NPJ BIOFILMS AND MICROBIOMES. 2020;6(1):39
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Journal article: JOURNAL OF HEPATOLOGY. 2020;73:s379
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Article: INTERNATIONAL JOURNAL OF CANCER. 2020;147(1):33-44
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Article: HELICOBACTER. 2020;25(3):e12688
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Article: JOURNAL OF GASTROENTEROLOGY. 2020;55(4):453-461
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Article: HUMAN GENOMICS. 2019;13(1):54
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Article: CANCER EPIDEMIOLOGY. 2019;62:101585
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Article: LANGENBECKS ARCHIVES OF SURGERY. 2019;404(6):703-709
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Article: GASTROENTEROLOGY CLINICS OF NORTH AMERICA. 2019;48(3):331-342
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Journal article: CANCER RESEARCH. 2019;79(13_Supplement):5049
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Journal article: NEPHROLOGY DIALYSIS TRANSPLANTATION. 2019;34(Supplement_1):gfz106.fp410
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Article: ACTA ONCOLOGICA. 2019;58(3):290-295
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Journal article: JOURNAL OF CLINICAL AND TRANSLATIONAL SCIENCE. 2019;3(Suppl 1):35
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Article: GUT. 2018;67(12):2092-2096
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Journal article: JAMA ONCOLOGY. 2018;4(11):1576-1582
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Article: ANNALS OF ONCOLOGY. 2018;29(8):1771-1776
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Article: GASTROINTESTINAL ENDOSCOPY. 2018;88(2):242-250.e1
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Journal article: SCIENCE TRENDS. 2018
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Article: BMJ OPEN. 2018;8(7):e021869
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Article: BMJ OPEN. 2018;8(5):e021495
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Journal article: GASTROENTEROLOGY. 2018;154(6):s-1113
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Article: CANCER EPIDEMIOLOGY. 2018;53:172-177
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Article: PROSTATE CANCER AND PROSTATIC DISEASES. 2018;21(1):147-152
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Journal article: EPIDEMIOLOGY OPEN ACCESS. 2018;8(4):1-9
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Article: UNITED EUROPEAN GASTROENTEROLOGY JOURNAL. 2017;5(8):1123-1128
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Article: BMJ OPEN. 2017;7(10):e017739
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Article: EUROPEAN JOURNAL OF CANCER. 2017;84:60-68
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Article: MYCOSES. 2017;60(9):576-580
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Article: SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY. 2017;52(6-7):678-685
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Article: BMJ OPEN. 2017;7(6):e016505
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Article: INTERNATIONAL JOURNAL OF CANCER. 2017;140(7):1693-1699
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Article: METHODS OF INFORMATION IN MEDICINE. 2017;56(5):401-406
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Article: SURGERY FOR OBESITY AND RELATED DISEASES. 2017;13(1):28-34
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Article: LANGENBECKS ARCHIVES OF SURGERY. 2016;401(6):851-859
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Article: ANNALS OF BURNS AND FIRE DISASTERS. 2016;29(2):123-129
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Article: BRITISH JOURNAL OF SURGERY. 2016;103(7):863-870
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Journal article: NEPHROLOGY DIALYSIS TRANSPLANTATION. 2016;31(suppl_1):i187-i188
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Article: BURNS. 2016;42(2):421-427
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Article: ANNALS OF SURGERY. 2016;263(2):251-257
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Article: ANNALS OF EPIDEMIOLOGY. 2015;25(12):948-954
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Article: ACTA ONCOLOGICA. 2015;54(6):903-908
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Article: CRITICAL CARE. 2015;19(1):7
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Article: PLOS ONE. 2015;10(3):e0121928
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Article: PLOS ONE. 2015;10(3):e0121080
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Article: INTERNATIONAL JOURNAL OF CANCER. 2014;135(9):2183-2190
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Article: BMJ OPEN. 2014;4(6):e005418
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Article: INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS. 2014;43(2):165-169
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Article: BMJ OPEN. 2013;3(12):e003754
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Article: BURNS. 2013;39(5):997-1003
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Article: LANGENBECKS ARCHIVES OF SURGERY. 2013;398(5):717-722
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Article: PLOS ONE. 2013;8(1):e52562
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Article: AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. 2012;186(1):56-64
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Article: BURNS. 2012;38(3):364-370
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Article: EUROPEAN JOURNAL OF INTERNAL MEDICINE. 2011;22(5):E39-E44
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Journal article: BURNS. 2011;37:s22
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Journal article: BURNS. 2011;37:s7
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Journal article: BURNS. 2011;37:s2
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Journal article: JOURNAL OF EPIDEMIOLOGY AND COMMUNITY HEALTH. 2011;65(Suppl 1):a64-A65
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Article: AMERICAN JOURNAL OF CRITICAL CARE. 2010;19(6):E81-E87
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Article: CRITICAL CARE. 2010;14(5):r188
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Article: BURNS. 2009;35(7):1009-1014
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Journal article: BURNS. 2009;35:s4-s5
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Article: BRITISH JOURNAL OF SURGERY. 2008;96(1):111-117
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Article: ACTA CHIRURGICA BELGICA. 2008;108(6):645-650
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Journal article: CRITICAL CARE. 2006;10(Suppl 1):p424
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Journal article: CRITICAL CARE. 2006;10(Suppl 1):p426
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Article: INTENSIVE CARE MEDICINE. 2005;31(12):1648-1653
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Journal article: CRITICAL CARE. 2005;9(Suppl 1):p209
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All other publications
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Review: JOURNAL OF INFECTION. 2024;89(2):106189
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Meeting abstract: ANNALS OF ONCOLOGY. 2023;34:S8
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Review: BMJ OPEN DIABETES RESEARCH & CARE. 2023;11(1):e003136
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Preprint: RESEARCH SQUARE. 2023
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Conference publication: BRITISH JOURNAL OF SURGERY. 2023;110
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Conference publication: PHARMACOEPIDEMIOLOGY AND DRUG SAFETY. 2023;32:77-78
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Conference publication: ACTA OBSTETRICIA ET GYNECOLOGICA SCANDINAVICA. 2023;102:64
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Review: ADVANCES IN NUTRITION. 2023;14(1):22-29
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Conference publication: HUMAN REPRODUCTION. 2023;38
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Review: FRONTIERS IN IMMUNOLOGY. 2023;14:1249330
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Book chapter: SWEDEN’S PANDEMIC EXPERIMENT. 2022;p. 169-190
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Preprint: MEDRXIV. 2022
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Review: BRITISH JOURNAL OF SURGERY. 2022;109(2):191-199
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Preprint: SSRN ELECTRONIC JOURNAL. 2022
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Corrigendum: HUMANITIES & SOCIAL SCIENCES COMMUNICATIONS. 2022;9(1):239
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Preprint: SSRN ELECTRONIC JOURNAL. 2022
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Review: JOURNAL OF VIRAL HEPATITIS. 2021;28(10):1431-1442
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Review: SURGICAL INNOVATION. 2021;28(4):409-418
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Review: ACTA CHIRURGICA BELGICA. 2021;121(4):248-253
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Letter: INTERNATIONAL JOURNAL OF SURGERY. 2021;91:105994
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Review: EUROPEAN JOURNAL OF CANCER. 2021;152:165-182
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Review: ACTA CHIRURGICA BELGICA. 2021;121(3):215-218
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Letter: JOURNAL OF GASTROENTEROLOGY. 2021;56(3):295-296
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Conference publication: REPRODUCTIVE SCIENCES. 2021;28(SUPPL 1):115A
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Review: THERAPEUTIC ADVANCES IN GASTROENTEROLOGY. 2021;14:17562848211051463-175628482110514
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Review: PHARMACOLOGICAL RESEARCH. 2020;160:105072
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Letter: LANCET. 2020;396(10248):e15
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Letter: ALIMENTARY PHARMACOLOGY & THERAPEUTICS. 2020;52(4):740-741
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Review: JOURNAL OF DEVELOPMENTAL ORIGINS OF HEALTH AND DISEASE. 2020;11(4):309-316
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Review: JOURNAL OF CLINICAL PERIODONTOLOGY. 2020;47:199-238
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Letter: GUT. 2020;69(6):1149-1150
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Review: INTERNATIONAL JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY. 2020;49(4):496-504
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Letter: GASTROENTEROLOGY. 2020;158(4):1172-1173
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Review: ALIMENTARY PHARMACOLOGY & THERAPEUTICS. 2020;51(4):410-420
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Review: INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH. 2020;17(2):E647-647
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Conference publication: JOURNAL OF HEPATOLOGY. 2020;73:S379
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Preprint: SSRN ELECTRONIC JOURNAL. 2020
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Review: BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY. 2020;127(2):171-180
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Preprint: SSRN ELECTRONIC JOURNAL. 2020
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Letter: AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY. 2019;221(2):172-173
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Meeting abstract: CANCER RESEARCH. 2019;79(13):5049
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Review: AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY. 2019;221(1):9-18.e8
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Conference publication: NEPHROLOGY DIALYSIS TRANSPLANTATION. 2019;34
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Preprint: SSRN ELECTRONIC JOURNAL. 2019
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Review: NEPHROLOGY DIALYSIS TRANSPLANTATION. 2019;34(1):146-156
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Review: JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY. 2018;76(10):2210.e1-2210.e13
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Review: INTERNATIONAL JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY. 2018;47(9):1095-1105
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Letter: CANCER EPIDEMIOLOGY. 2018;54:139-140
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Conference publication: GASTROENTEROLOGY. 2018;154(6):S1113
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Review: ORAL DISEASES. 2017;23(7):889-896
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Review: AMERICAN JOURNAL OF KIDNEY DISEASES. 2016;68(6):923-932
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Review: JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE. 2016;108(9):djw132
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Review: ACTA CHIRURGICA BELGICA. 2016;116(4):239-242
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Conference publication: NEPHROLOGY DIALYSIS TRANSPLANTATION. 2016;31:187-188
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Review: JOURNAL OF CRANIO-MAXILLOFACIAL SURGERY. 2016;44(1):6-15
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Conference publication: INTERNATIONAL JOURNAL OF EPIDEMIOLOGY. 2015;44:168-169
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Book chapter: OXFORD TEXTBOOK OF CLINICAL NEPHROLOGY. 2015;p. 2151-2158
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Conference publication: INTERNATIONAL JOURNAL OF EPIDEMIOLOGY. 2015;44:187-188
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Editorial comment: BMJ-BRITISH MEDICAL JOURNAL. 2015;350:h3169
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Review: NEDERLANDS TIJDSCHRIFT VOOR GENEESKUNDE. 2015;159:A8915
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Review: GUT. 2014;63(9):1393-U188
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Review: ACTA CHIRURGICA BELGICA. 2014;114(3):212-214
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Review: INTENSIVE CARE MEDICINE. 2013;39(3):365-375
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Review: INTERNATIONAL WOUND JOURNAL. 2013;10(1):6-12
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Review: ACTA CLINICA BELGICA. 2012;67(6):438-441
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Review: ANNALS OF INTENSIVE CARE. 2011;1:47
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Review: LANCET INFECTIOUS DISEASES. 2011;11(11):845-854
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Letter: EUROPEAN JOURNAL OF TRAUMA AND EMERGENCY SURGERY. 2011;37(5):533-534
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Letter: CRITICAL CARE MEDICINE. 2011;39(9):2202-2203
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Conference publication: INTENSIVE CARE MEDICINE. 2011;37:S172
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Conference publication: INTENSIVE CARE MEDICINE. 2011;37:S111
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Letter: BURNS. 2010;36(8):1318-1320
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Review: BURNS. 2010;36(8):1157-1164
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Review: JOURNAL OF SURGICAL RESEARCH. 2010;164(1):E115-E123
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Review: INTENSIVE CARE MEDICINE. 2010;36(6):915-925
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Review: JOURNAL OF TRAUMA. 2010;68(2):490-501
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Conference publication: ACTA CLINICA BELGICA. 2010;65(6):461
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Conference publication: ACTA CLINICA BELGICA. 2010;65(6):461
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Conference publication: INTENSIVE CARE MEDICINE. 2010;36:S250
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Conference publication: INTENSIVE CARE MEDICINE. 2010;36:S91
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Conference publication: INTENSIVE CARE MEDICINE. 2010;36:S91
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Conference publication: ACTA CLINICA BELGICA. 2010;65(6):461
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Letter: AMERICAN JOURNAL OF CRITICAL CARE. 2009;18(6):507-508
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Letter: CRITICAL CARE MEDICINE. 2009;37(11):2998-2999
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Meeting abstract: VALUE IN HEALTH. 2009;12(7):A418
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Letter: INTENSIVE CARE MEDICINE. 2009;35(10):1818-1819
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Letter: JOURNAL OF TRAUMA. 2009;67(2):415
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Corrigendum: JOURNAL OF TRAUMA. 2009;67(4):896
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Letter: BURNS. 2007;33(7):939-940
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Letter: PLASTIC AND RECONSTRUCTIVE SURGERY. 2007;120(1):360-361
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Letter: BURNS. 2007;33(4):538-539
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Grants
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Swedish Research Council1 January 2024 - 31 December 2026
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Swedish Research Council1 January 2021 - 31 December 2023
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Swedish Research Council1 January 2014 - 31 December 2018
Employments
- Researcher, Department of Women's and Children's Health, Karolinska Institutet, 2024-
Degrees and Education
- Docent, Karolinska Institutet, 2015
Supervisor
- Hanna Danielsson, The role of early-life events on protein expression and gut microbiome in extreme preterm infants, 2020