Natalija Buza-Vidas

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Articles

Article: BLOOD. 2018;131(15):1712-1719

Canonical Notch signaling is dispensable for adult steady-state and stress myelo-erythropoiesis.

Duarte S; Woll PS; Buza-Vidas N; Chin DWL; Boukarabila H; Luís TC; Stenson L; Bouriez-Jones T; Ferry H; Mead AJ; Atkinson D; Jin S; Clark S-A; Wu B; Repapi E; Gray N; Taylor S; Mutvei AP; Tsoi YL; Nerlov C; Lendahl U; Jacobsen SEW
Journal article: EXPERIMENTAL HEMATOLOGY. 2016;44(9):s46

DISTINCT MYELOID PROGENITOR DIFFERENTIATION PATHWAYS IDENTIFIED THROUGH SINGLE CELL RNA SEQUENCING

Nerlov C; Drissen R; Buza-Vidas N; Woll P; Thongjuea S; Gambardella A; Giustacchini A; Jacobsen SE
Article: NATURE IMMUNOLOGY. 2016;17(6):666-676

Distinct myeloid progenitor-differentiation pathways identified through single-cell RNA sequencing.

Drissen R; Buza-Vidas N; Woll P; Thongjuea S; Gambardella A; Giustacchini A; Mancini E; Zriwil A; Lutteropp M; Grover A; Mead A; Sitnicka E; Jacobsen SEW; Nerlov C
Journal article: STEM CELL RESEARCH. 2013;11(3):1129-1136

PRDM11 is dispensable for the maintenance and function of hematopoietic stem and progenitor cells.

Thoren LA; Fog CK; Jensen KT; Buza-Vidas N; Côme C; Lund AH; Porse BT
Article: CELL REPORTS. 2013;3(6):1766-1776

FLT3-ITDs instruct a myeloid differentiation and transformation bias in lymphomyeloid multipotent progenitors.

Mead AJ; Kharazi S; Atkinson D; Macaulay I; Pecquet C; Loughran S; Lutteropp M; Woll P; Chowdhury O; Luc S; Buza-Vidas N; Ferry H; Clark S-A; Goardon N; Vyas P; Constantinescu SN; Sitnicka E; Nerlov C; Jacobsen SEW
Article: BLOOD. 2012;120(12):2412-2416

Dicer is selectively important for the earliest stages of erythroid development.

Buza-Vidas N; Cismasiu VB; Moore S; Mead AJ; Woll PS; Lutteropp M; Melchiori L; Luc S; Bouriez-Jones T; Atkinson D; O'Carroll D; Jacobsen SEW; Nerlov C
Article: NATURE IMMUNOLOGY. 2012;13(4):412-419

The earliest thymic T cell progenitors sustain B cell and myeloid lineage potential.

Luc S; Luis TC; Boukarabila H; Macaulay IC; Buza-Vidas N; Bouriez-Jones T; Lutteropp M; Woll PS; Loughran SJ; Mead AJ; Hultquist A; Brown J; Mizukami T; Matsuoka S; Ferry H; Anderson K; Duarte S; Atkinson D; Soneji S; Domanski A; Farley A; Sanjuan-Pla A; Carella C; Patient R; de Bruijn M; Enver T; Nerlov C; Blackburn C; Godin I; Jacobsen SEW
Article: PLOS GENETICS. 2011;7(12):e1002404

Acute multiple organ failure in adult mice deleted for the developmental regulator Wt1.

Chau Y-Y; Brownstein D; Mjoseng H; Lee W-C; Buza-Vidas N; Nerlov C; Jacobsen SE; Perry P; Berry R; Thornburn A; Sexton D; Morton N; Hohenstein P; Freyer E; Samuel K; van't Hof R; Hastie N
Article: BLOOD. 2011;118(13):3613-3621

Impact of gene dosage, loss of wild-type allele, and FLT3 ligand on Flt3-ITD-induced myeloproliferation.

Kharazi S; Mead AJ; Mansour A; Hultquist A; Böiers C; Luc S; Buza-Vidas N; Ma Z; Ferry H; Atkinson D; Reckzeh K; Masson K; Cammenga J; Rönnstrand L; Arai F; Suda T; Nerlov C; Sitnicka E; Jacobsen SEW
Article: BLOOD. 2011;118(6):1544-1548

FLT3 expression initiates in fully multipotent mouse hematopoietic progenitor cells.

Buza-Vidas N; Woll P; Hultquist A; Duarte S; Lutteropp M; Bouriez-Jones T; Ferry H; Luc S; Jacobsen SEW
Article: BLOOD. 2011;118(5):1291-1293

GATA3 is redundant for maintenance and self-renewal of hematopoietic stem cells.

Buza-Vidas N; Duarte S; Luc S; Bouriez-Jones T; Woll PS; Jacobsen SEW
Article: BLOOD. 2011;117(13):3521-3528

Hoxb4-YFP reporter mouse model: a novel tool for tracking HSC development and studying the role of Hoxb4 in hematopoiesis.

Hills D; Gribi R; Ure J; Buza-Vidas N; Luc S; Jacobsen SEW; Medvinsky A
Article: NEW ENGLAND JOURNAL OF MEDICINE. 2010;363(11):1025-1037

Persistent malignant stem cells in del(5q) myelodysplasia in remission.

Tehranchi R; Woll PS; Anderson K; Buza-Vidas N; Mizukami T; Mead AJ; Astrand-Grundström I; Strömbeck B; Horvat A; Ferry H; Dhanda RS; Hast R; Rydén T; Vyas P; Göhring G; Schlegelberger B; Johansson B; Hellström-Lindberg E; List A; Nilsson L; Jacobsen SEW
Article: BLOOD. 2010;115(24):5061-5068

Expression and role of FLT3 in regulation of the earliest stage of normal granulocyte-monocyte progenitor development.

Böiers C; Buza-Vidas N; Jensen CT; Pronk CJH; Kharazi S; Wittmann L; Sitnicka E; Hultquist A; Jacobsen SEW
Article: BLOOD. 2009;113(15):3453-3460

FLT3 receptor and ligand are dispensable for maintenance and posttransplantation expansion of mouse hematopoietic stem cells.

Buza-Vidas N; Cheng M; Duarte S; Charoudeh HN; Jacobsen SEW; Sitnicka E
Article: BLOOD. 2008;111(7):3424-3434

Down-regulation of Mpl marks the transition to lymphoid-primed multipotent progenitors with gradual loss of granulocyte-monocyte potential.

Luc S; Anderson K; Kharazi S; Buza-Vidas N; Böiers C; Jensen CT; Ma Z; Wittmann L; Jacobsen SEW
Article: CELL STEM CELL. 2007;1(6):671-684

Critical role of thrombopoietin in maintaining adult quiescent hematopoietic stem cells.

Qian H; Buza-Vidas N; Hyland CD; Jensen CT; Antonchuk J; Månsson R; Thoren LA; Ekblom M; Alexander WS; Jacobsen SEW
Article: BLOOD. 2007;110(8):2955-2964

Critical role of FLT3 ligand in IL-7 receptor independent T lymphopoiesis and regulation of lymphoid-primed multipotent progenitors.

Sitnicka E; Buza-Vidas N; Ahlenius H; Cilio CM; Gekas C; Nygren JM; Månsson R; Cheng M; Jensen CT; Svensson M; Leandersson K; Agace WW; Sigvardsson M; Jacobsen SEW
Article: CANCER CELL. 2007;12(4):367-380

FLT3 mutations confer enhanced proliferation and survival properties to multipotent progenitors in a murine model of chronic myelomonocytic leukemia.

Lee BH; Tothova Z; Levine RL; Anderson K; Buza-Vidas N; Cullen DE; McDowell EP; Adelsperger J; Fröhling S; Huntly BJP; Beran M; Jacobsen SE; Gilliland DG
Article: CURRENT OPINION IN HEMATOLOGY. 2007;14(4):315-321

Delineation of the earliest lineage commitment steps of haematopoietic stem cells: new developments, controversies and major challenges.

Buza-Vidas N; Luc S; Jacobsen SEW
Article: BLOOD. 2007;110(1):424-432

Crucial role of FLT3 ligand in immune reconstitution after bone marrow transplantation and high-dose chemotherapy.

Buza-Vidas N; Cheng M; Duarte S; Nozad H; Jacobsen SEW; Sitnicka E
Article: IMMUNITY. 2007;26(4):407-419

Molecular evidence for hierarchical transcriptional lineage priming in fetal and adult stem cells and multipotent progenitors.

Månsson R; Hultquist A; Luc S; Yang L; Anderson K; Kharazi S; Al-Hashmi S; Liuba K; Thorén L; Adolfsson J; Buza-Vidas N; Qian H; Soneji S; Enver T; Sigvardsson M; Jacobsen SEW
Journal article: BLOOD. 2006;108(11):3208

Crucial Role of FLT3 Ligand in Immune Reconstitution Following Bone Marrow Transplantation and High Dose Chemotherapy.

Buza-Vidas N; Cheng M; Duarte S; Jacobsen SEW; Sitnicka E
Article: GENES & DEVELOPMENT. 2006;20(15):2018-2023

Cytokines regulate postnatal hematopoietic stem cell expansion: opposing roles of thrombopoietin and LNK.

Buza-Vidas N; Antonchuk J; Qian H; Månsson R; Luc S; Zandi S; Anderson K; Takaki S; Nygren JM; Jensen CT; Jacobsen SEW
Journal article: BLOOD. 2005;106(11):339

Critical Role of flt3 in Fetal and Adult T Lymphopoiesis.

Sitnicka E; Buza-Vidas N; Ahlenius H; Cilio CM; Gekas C; Nygren JM; Jensen CT; Svensson M; Agace WW; Jacobsen SEW
Journal article: BLOOD. 2005;106(11):802

Evidence for a Novel Blood Lineage Commitment Pathway from Lympho-Myeloid Hematopoietic Stem Cells.

Jacobsen SEW; Mansson R; Hultquist A; Sigvardsson M; Buza-Vidas N; Thoren L; Liuba K; Luc S; Yang L
Article: CELL. 2005;121(2):295-306

Identification of Flt3+ lympho-myeloid stem cells lacking erythro-megakaryocytic potential a revised road map for adult blood lineage commitment.

Adolfsson J; Månsson R; Buza-Vidas N; Hultquist A; Liuba K; Jensen CT; Bryder D; Yang L; Borge O-J; Thoren LAM; Anderson K; Sitnicka E; Sasaki Y; Sigvardsson M; Jacobsen SEW
Journal article: BLOOD. 2004;104(11):112

Critical and Complementary Role of FLT3 and Interleukin 7-Receptor Alpha Signaling in T Lymphocyte Development.

Buza-Vidas N; Ahlenius H; Cilio CM; Svensson M; Agace W; Jacobsen SEW; Sitnicka E
Article: JOURNAL OF EXPERIMENTAL MEDICINE. 2003;198(10):1495-1506

Complementary signaling through flt3 and interleukin-7 receptor alpha is indispensable for fetal and adult B cell genesis.

Sitnicka E; Brakebusch C; Martensson I-L; Svensson M; Agace WW; Sigvardsson M; Buza-Vidas N; Bryder D; Cilio CM; Ahlenius H; Maraskovsky E; Peschon JJ; Jacobsen SEW
Article: BLOOD. 2003;102(3):881-886

Human CD34+ hematopoietic stem cells capable of multilineage engrafting NOD/SCID mice express flt3: distinct flt3 and c-kit expression and response patterns on mouse and candidate human hematopoietic stem cells.

Sitnicka E; Buza-Vidas N; Larsson S; Nygren JM; Liuba K; Jacobsen SEW
Article: IMMUNITY. 2002;17(4):463-472

Key role of flt3 ligand in regulation of the common lymphoid progenitor but not in maintenance of the hematopoietic stem cell pool.

Sitnicka E; Bryder D; Theilgaard-Mönch K; Buza-Vidas N; Adolfsson J; Jacobsen SEW
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All other publications

Review: SEMINARS IN IMMUNOLOGY. 2008;20(4):213-220

Delineating the cellular pathways of hematopoietic lineage commitment.

Luc S; Buza-Vidas N; Jacobsen SEW
Published conference paper: ANNALS OF THE NEW YORK ACADEMY OF SCIENCES. 2007;1106:89-94

Biological and molecular evidence for existence of lymphoid-primed multipotent progenitors.

Luc S; Buza-Vidas N; Jacobsen SEW

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Identification of new potential epigenetic targets for treatment of myelomatosis.

Danish cancer society

1 January 2014 - 31 December 2015

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