Natalie Geyer
About me
I am a cancer biologist at the Division of Surgery and Oncology (CLINTEC, Karolinska Institutet), where my research in the Cancer Cell Invasion Lab (group leader: Marco Gerling) centres on understanding microenvironmental control of tumor invasion.
Research
Tumors reshape their surrounding cellular niches forming a growth-promoting microenvironment. However, so far, little is known about the role of epithelial host cells in this context, especially in the metastatic setting. Using liver metastasis resections from Karolinska University Hospital in Huddinge together with murine disease models, I study cellular communication mechanisms that drive tumor-host interactions at the invasive edge of metastases. Our work connects spatially resolved and mechanistic approaches to clinical questions, and is rooted in close collaboration across disciplines.
Teaching
With a passion for lecturing and science communication, I engage in various teaching activities.
Lecturer
- Lecture on "Transfection and reporter genes" (Bachelor in Biomedicine, course "Genetics, Genomics and Functional Genomics", Karolinska Institutet, 2026)
- Lecture on cancer biology for high school students (Ung Vetenskapssort, Biology camp, 2026)
- Lecture on "Pancreatic cancer mouse models" (Ph.D. course "Incurable Cancers", Karolinska Institutet, 2022)
Supervision & other activities- Continuous supervision of lab internships for students from Karolinska Institutet or abroad
- Teacher opponent and master thesis examiner (Master in Biomedicine, Lund University, 2025)
- Master thesis examiner (Master in Nutrition Science, Karolinska Institutet, 2024
- Mentor and teacher (Master in Nutrition Science, course "Molecular and genetic mechanisms in nutrition science", Karolinska Institutet, 2023)
Articles
- Article: NATURE COMMUNICATIONS. 2025;16(1):8307Soderqvist S; Viljamaa A; Geyer N; Keller A-L; Ruksha K; Strell C; Hekmati N; Niculae A; Engstrand J; Sparrelid E; Salmen C; Costa TDF; Zhao M; Stromblad S; Zacharouli A; Ghorbani P; Harrizi S; Hamidi Y; Khorosjutina O; Milanova S; Schmierer B; Bozoky B; Fernandez Moro C; Gerling M
- Article: CURRENT OPINION IN CELL BIOLOGY. 2024;86:102315Moro CF; Geyer N; Gerling M
- Article: NATURE COMMUNICATIONS. 2023;14(1):5024Moro CF; Geyer N; Harrizi S; Hamidi Y; Soderqvist S; Kuznyecov D; Tidholm Qvist E; Salmonson Schaad M; Hermann L; Lindberg A; Heuchel RL; Martin-Bernabe A; Dhanjal S; Navis AC; Villard C; del Valle AC; Bozoky L; Sparrelid E; Dirix L; Strell C; Ostman A; Schmierer B; Vermeulen PB; Engstrand J; Bozoky B; Gerling M
- Article: NEOPLASIA. 2021;23(12):1300-1306Bozoky B; Moro CF; Strell C; Geyer N; Heuchel RL; Lohr JM; Ernberg I; Szekely L; Gerling M; Bozoky B
- Article: ONCOGENE. 2021;40(31):4955-4966Bauer J; Cuvelier N; Ragab N; Simon-Keller K; Nitzki F; Geyer N; Botermann DS; Elmer DP; Rosenberger A; Rando TA; Biressi S; Fagin JA; Saur D; Dullin C; Schildhaus H-U; Schulz-Schaeffer W; Aberger F; Uhmann A; Hahn H
- Article: NATURE METHODS. 2021;18(8):912-920Andrews N; Serviss JT; Geyer N; Andersson AB; Dzwonkowska E; Sutevski I; Heijboer R; Baryawno N; Gerling M; Enge M
- Article: FRONTIERS IN PEDIATRICS. 2018;6:378Ragab N; Viehweger F; Bauer J; Geyer N; Yang M; Seils A; Belharazem D; Brembeck FH; Schildhaus H-U; Marx A; Hahn H; Simon-Keller K
- Article: FRONTIERS IN ONCOLOGY. 2018;8:396Geyer N; Ridzewski R; Bauer J; Kuzyakova M; Dittmann K; Dullin C; Rosenberger A; Schildhaus H-U; Uhmann A; Fulda S; Hahn H
- Article: PLANTA. 2014;239(1):213-229Mueller WEG; Qiang L; Schroder HC; Honig N; Yuan D; Grebenjuk VA; Mussino F; Giovine M; Wang X
All other publications
- Preprint: BIORXIV. 2026Gao C; Martino M; Chaurasiya A; Casagrande FB; Lim JP; van Ekelenburg YS; Feng W; Liu Y; Scholz B; Mishra P; Thippana M; Torkornoo D; Chau PK; Khan R; Tannaes TM; Tzelepis I; Chacoua I; Geyer N; Meltzer S; Ree AH; Gerling M; Hartman J; Kiani N; Ohlsson R; Göndör A
- Preprint: BIORXIV. 2024Söderqvist S; Viljamaa A; Geyer N; Strell C; Hekmati N; Engstrand J; Sparrelid E; Salmén C; Heuchel R; Zacharouli A; Ghorbani P; Harrizi S; Hamidi Y; Khorosjutina O; Milanova S; Schmierer B; Bozóky B; Moro CF; Gerling M
- Letter: BJC REPORTS. 2023;1(1):19Fernandez Moro C; Bozoky B; Geyer N; Engstrand J; Dirix L; Vermeulen P; Gerling M
- Review: BRITISH JOURNAL OF CANCER. 2022;127(6):988-1013Latacz E; Hoppener D; Bohlok A; Leduc S; Tabaries S; Fernandez Moro C; Lugassy C; Nystrom H; Bozoky B; Floris G; Geyer N; Brodt P; Llado L; Van Mileghem L; De Schepper M; Majeed AW; Lazaris A; Dirix P; Zhang Q; Petrillo SK; Vankerckhove S; Joye I; Meyer Y; Gregorieff A; Roig NR; Vidal-Vanaclocha F; Denis L; Oliveira RC; Metrakos P; Grunhagen DJ; Nagtegaal ID; Mollevi DG; Jarnagin WR; D'Angelica MI; Reynolds AR; Doukas M; Desmedt C; Dirix L; Donckier V; Siegel PM; Barnhill R; Gerling M; Verhoef C; Vermeulen PB
- Preprint: MEDRXIV. 2022Fernández Moro C; Harrizi S; Hamidi Y; Geyer N; Kuznyecov D; Tidholm-Qvist E; Salmonson Schaad M; del Valle A; Söderqvist S; Bozóky L; Sparrelid E; Dirix L; Vermeulen P; Bozóky B; Engstrand J; Gerling M
- Preprint: MEDRXIV. 2022Latacz E; Höppener D; Bohlok A; Leduc S; Tabariès S; Moro CF; Lugassy C; Nyström H; Bozóky B; Floris G; Geyer N; Brodt P; Llado L; Mileghem LV; Schepper MD; Majeed A; Lazaris A; Dirix P; Zhang Q; Petrillo S; Vankerckhove S; Joye I; Meyer Y; Gregorieff A; Roig NR; Vidal-Vanaclocha F; Denis L; Oliveira RC; Metrakos P; Grünhagen D; Nagtegaal I; Mollevi D; Jarnagin W; D’Angelica M; Reynolds A; Doukas M; Desmedt C; Dirix L; Donckier V; Siegel P; Barnhill R; Gerling M; Verhoef C; Vermeulen P
- Review: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2021;22(3):1025Geyer N; Gerling M
- Preprint: BIORXIV. 2020Serviss J; Andrews N; Andersson A; Dzwonkowska E; Heijboer R; Geyer N; Gerling M; Enge M
Grants
- Deutsche Forschungsgemeinschaft1 January 2021 - 31 December 2025
Employments
- Research Specialist, Department of Clinical Science, Intervention and Technology, Karolinska Institutet, 2025-
Visiting research fellowships
- Unraveling cellular crosstalk in liver metastases of gastrointestinal cancer:Multimodal analysis of metastatic invasion., Karolinska Institutet, 2019-2025
