Moustapha Hassan

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About me

Moustapha Hassan was appointed Professor of Transplantation Research at the Department of Laboratory Medicine in 2013. His research concerns improved survival and quality of life in cancer patients treated with chemotherapy and stem cell transplantation.

Articles

Article: CELL JOURNAL. 2024;26(8):505-514
Application of XBP1s Decoy Oligodeoxynucleotide Attenuates Cancerous Phenotype in Huh-7 Hepatocellular Carcinoma Cells
Bahadori S; Farzaneh Z; Solhi R; Hajilou Z; Shokouhian B; Hassan M; Najimi M; Vosough M
Article: EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS. 2024;203:114470
MiR-29a-laden extracellular vesicles efficiently induced apoptosis through autophagy blockage in HCC cells
Seydi H; Nouri K; Shokouhian B; Piryaei A; Hassan M; Cordani M; Zarrabi A; Shekari F; Vosough M
Article: JOURNAL OF CELLULAR AND MOLECULAR MEDICINE. 2024;28(18):e18507
Wharton's Jelly mesenchymal stem cell-derived extracellular vesicles induce liver fibrosis-resolving phenotype in alternatively activated macrophages
Torabi S; Zarrabi M; Shekari F; Poorkazem H; Lotfinia M; Bencina S; Gramignoli R; Hassan M; Najimi M; Vosough M
Article: INTERNATIONAL IMMUNOPHARMACOLOGY. 2024;129:111584
Tumor cell derived osteopontin and prostaglandin E2 synergistically promote the expansion of myeloid derived suppressor cells during the tumor immune escape phase
Mamand DR; Bazaz S; Mohammad DK; Saher O; Wiklander OPB; Sadeghi B; Hassan M; EL-Andaloussi S; Abedi-Valugerdi M
Article: HELIYON. 2024;10(2):e24948
Immunomodulatory performance of GMP-compliant, clinical-grade mesenchymal stromal cells from four different sources
Arki MK; Moeinabadi-Bidgoli K; Niknam B; Mohammadi P; Hassan M; Hossein-Khannazer N; Vosough M
Article: TRANSPLANTATION AND CELLULAR THERAPY. 2023;29(9):581.e1-581.e8
Interaction Between High-Dose Intravenous Busulfan and Post-Transplantation Cyclophosphamide on Hemorrhagic Cystitis After Allogeneic Hematopoietic Cell Transplantation
Carreira AS; Salas MQ; Remberger M; Novitzky-Basso I; Law AD; Lam W; Pasic I; Mazzulli T; Cserti-Gazdewich C; Kim DDH; Michelis FV; Viswabandya A; Gerbitz A; Lipton JH; Kumar R; Hassan M; Mattsson J
Article: CELL JOURNAL. 2023;25(8):524-535
Umbilical Cord Blood-Derived Monocytes as A Reliable Source of Functional Macrophages for Biomedical Research
Torabi S; Zarrabi M; Hossein-Khannazer N; Lotfinia M; Nouri M; Gramignoli R; Hassan M; Vosough M
Article: NANO TODAY. 2023;50:101824
NIR light-driven photocatalytic NAD(P)H oxidation and H2O2 generation in situ for enhanced chemodynamic therapy and immune response
Zhang C; Huang J; Guo X; Da X; Dai Z; Hassan M; Yu Y; Wang X; Zhou Q
Article: JOURNAL FOR IMMUNOTHERAPY OF CANCER. 2023;11(2):e005691
Tuned activation of MSLN-CAR T cells induces superior antitumor responses in ovarian cancer models
Schoutrop E; Poiret T; El-Serafi I; Zhao Y; He R; Moter A; Henriksson J; Hassan M; Magalhaes I; Mattsson J
Article: PHYTOMEDICINE. 2023;110:154634
Celastrol targets the ChREBP-TXNIP axis to ameliorates type 2 diabetes mellitus
Zhou D; Li X; Xiao X; Wang G; Chen B; Song Y; Liu X; He Q; Zhang H; Wu Q; Zhang L; Wu L; Shen Z; Hassan M; Zhao Y; Zhou W
Article: MOLECULAR AND CELLULAR BIOCHEMISTRY. 2023;478(1):23-37
Novel antigens for targeted radioimmunotherapy in hepatocellular carcinoma
Mahsa P; Asadian S; Mirzaei H; Minaei A; Shahriari E; Shpichka A; Es HA; Timashev P; Hassan M; Vosough M
Article: JOURNAL OF BIOMEDICAL NANOTECHNOLOGY. 2023;19(1):28-35
Perfluorocarbon-Encapsulated Porphyrin-Lipid Nanoparticles as a Photoactive Pyroptosis Inducer for Cancer Therapy
Lin X; Jiang X; Xu Y; Liu R; Zhang N; Li R; Xiang H; Zhao C; Zhao Z; Zeng W; Qu S; Tan X; Cheng C; Chen X; Wang M; Liu Y; Liu L; Zhao Y; Dai Z; Hassan M; Sun D
Article: STEM CELLS INTERNATIONAL. 2022;2022:1850305-14
Conjugated Linoleic Acid Treatment Attenuates Cancerous features in Hepatocellular Carcinoma Cells
Miri-Lavasani Z; Torabi S; Solhi R; Shokouhian B; Afsharian P; Heydari Z; Piryaei A; Farzaneh Z; Hossein-khannazer N; Es HA; Zahmatkesh E; Nussler A; Hassan M; Najimi M; Vosough M
Article: INTERNATIONAL IMMUNOPHARMACOLOGY. 2022;106:108587
Novel insights in CAR-NK cells beyond CAR-T cell technology; promising advantages
Ebrahimiyan H; Tamimi A; Shokoohian B; Minaei N; Memarnejadian A; Hossein-Khannazer N; Hassan M; Vosough M
Article: TRANSPLANTATION AND CELLULAR THERAPY. 2022;28(4):196-202
Association Between the Magnitude of Intravenous Busulfan Exposure and Development of Hepatic Veno-Occlusive Disease in Children and Young Adults Undergoing Myeloablative Allogeneic Hematopoietic Cell Transplantation
Bognar T; Bartelink IH; Egberts TCG; Rademaker CMA; Versluys AB; Slatter MA; Kletzel M; Nath CE; Cuvelier GDE; Savic RM; Dvorak C; Long-Boyle JR; Cowan MJ; Bittencourt H; Bredius RGM; Gungor T; Shaw PJ; Ansari M; Hassan M; Krajinovic M; Hempel G; Marktel S; Chiesa R; Theoret Y; Lund T; Orchard PJ; Wynn RF; Boelens JJ; Lalmohamed A
Article: BMJ GLOBAL HEALTH. 2022;7(4):e008143
Derivation and validation of a novel risk assessment tool to identify children aged 2-59 months at risk of hospitalised pneumonia-related mortality in 20 countries
Rees CA; Colbourn T; Hooli S; King C; Lufesi N; McCollum ED; Mwansambo C; Cutland C; Madhi SA; Nunes M; Matthew JL; Addo-Yobo E; Chisaka N; Hassan M; Hibberd PL; Jeena PM; Lozano JM; MacLeod WB; Patel A; Thea DM; Nguyen NTV; Kartasasmita CB; Lucero M; Awasthi S; Bavdekar A; Chou M; Nymadawa P; Pape J-W; Paranhos-Baccala G; Picot VS; Rakoto-Andrianarivelo M; Rouzier V; Russomando G; Sylla M; Vanhems P; Wang J; Asghar R; Banajeh S; Iqbal I; Maulen-Radovan I; Mino-Leon G; Saha SK; Santosham M; Singhi S; Basnet S; Strand TA; Bhatnagar S; Wadhwa N; Lodha R; Aneja S; Clara AW; Campbell H; Nair H; Falconer J; Qazi SA; Nisar YB; Neuman MI
Article: CELLS. 2022;11(2):305
Rhenium Perrhenate (¹⁸⁸ReO₄) Induced Apoptosis and Reduced Cancerous Phenotype in Liver Cancer Cells
Asadian S; Piryaei A; Gheibi N; Kalantari BA; Davarpanah MR; Azad M; Kapustina V; Alikhani M; Nejad SM; Alikhani HK; Mohamadi M; Shpichka A; Timashev P; Hassan M; Vosough M
Article: NPJ BREAST CANCER. 2022;8(1):2
Endoplasmic reticulum stress inhibits AR expression via the PERK/eIF2α/ATF4 pathway in luminal androgen receptor triple-negative breast cancer and prostate cancer
Li X; Zhou D; Cai Y; Yu X; Zheng X; Chen B; Li W; Zeng H; Hassan M; Zhao Y; Zhou W
Article: JOURNAL OF PERSONALIZED MEDICINE. 2022;12(1):42
COL-3-Induced Molecular and Ultrastructural Alterations in K562 Cells
Fares M; Oerther S; Hultenby K; Gubrianska D; Zhao Y; Abedi-Valugerdi M; Hassan M
Article: CANCER RESEARCH. 2021;81(11):3022-3035
Mesothelin-Specific CAR T Cells Target Ovarian Cancer
Schoutrop E; El-Serafi I; Poiret T; Zhao Y; Gultekin O; He R; Moyano-Galceran L; Carlson JW; Lehti K; Hassan M; Magalhaes I; Mattsson J
Article: INTERNATIONAL JOURNAL OF PHARMACEUTICS. 2021;601:120588
Biodistribution of fluorescence-labelled EGF protein from slow release NanoZolid depots in mouse
Gruden S; Brunmark C; Holmqvist B; Brenndorfer ED; Johansson M; Liu J; Zhao Y; Axen N; Hassan M
Article: BONE MARROW TRANSPLANTATION. 2021;56(4):807-817
Vitamin D levels and busulphan kinetics in patients undergoing hematopoietic stem cell transplantation, a multicenter study
El-Serafi A; He R; Zheng W; Benkossou F; Oerther S; Zhao Y; Mellgren K; Gustafsson B; Heilmann C; Kanerva J; Lotfi K; Toporski J; Sundin M; Hoglund M; Mattsson J; El-Serafi I; Hassan M
Article: SCIENTIFIC REPORTS. 2021;11(1):2707
Cyclophosphamide exposure assessed with the biomarker phosphoramide mustard-hemoglobin in breast cancer patients: The TailorDose I study
Gernaat SAM; von Stedingk H; Hassan M; Nilsson HP; Rodriguez-Wallberg KA; Hedayati E; Rydberg P
Article: ACS APPLIED MATERIALS & INTERFACES. 2020;12(48):53665-53681
Multimodal Imaging of Pancreatic Ductal Adenocarcinoma Using Multifunctional Nanoparticles as Contrast Agents
Zhao Y; Ye F; Brismar TB; Li X; He R; Heuchel R; El-Sayed R; Feliu N; Zheng W; Oerther S; Dutta J; Parak WJ; Muhammed M; Hassan M
Article: PHARMACOLOGICAL RESEARCH. 2020;160:105070
β-radiating radionuclides in cancer treatment, novel insight into promising approach
Asadian S; Mirzaei H; Kalantari BA; Davarpanah MR; Mohamadi M; Shpichka A; Nasehi L; Es HA; Timashev P; Najimi M; Gheibi N; Hassan M; Vosough M
Article: BLOOD ADVANCES. 2020;4(9):1998-2010
Targeted busulfan-based reduced-intensity conditioning and HLA-matched HSCT cure hemophagocytic lymphohistiocytosis
Felber M; Steward CG; Kentouche K; Fasth A; Wynn RF; Zeilhofer U; Haunerdinger V; Volkmer B; Prader S; Gruhn B; Ehl S; Lehmberg K; Mueller D; Gennery AR; Albert MH; Hauck F; Rao K; Veys P; Hassan M; Lankester AC; Schmid JP; Hauri-Hohl MM; Guengoer T
Article: EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES. 2020;143:105158
Pharmacokinetic profile of N-acetylcysteine amide and its main metabolite in mice using new analytical method
He R; Zheng W; Ginman T; Ottosson H; Norgren S; Zhao Y; Hassan M
Article: SCIENTIFIC REPORTS. 2020;10(1):1274
A general covalent binding model between cytotoxic selenocompounds and albumin revealed by mass spectrometry and X-ray absorption spectroscopy
Zheng W; He R; Boada R; Subirana MA; Ginman T; Ottosson H; Valiente M; Zhao Y; Hassan M
Article: FRONTIERS IN PHARMACOLOGY. 2020;11:406
Population Pharmacokinetic, Pharmacogenetic, and Pharmacodynamic Analysis of Cyclophosphamide in Ethiopian Breast Cancer Patients
Ahmed JH; Makonnen E; Bisaso RK; Mukonzo JK; Fotoohi A; Aseffa A; Howe R; Hassan M; Aklillu E
Article: INTERNATIONAL IMMUNOPHARMACOLOGY. 2020;78:106042
The kidney injury caused by the onset of acute graft-versus-host disease is associated with down-regulation of αKlotho
Amin R; He R; Gupta D; Zheng W; Burmakin M; Mohammad DK; DePierre JW; Sadeghi B; Olauson H; Wernerson A; El-Andaloussi S; Hassan M; Abedi-Valugerdi M
Article: CLINICAL TRANSPLANTATION. 2019;33(12):e13742
Bone and hormonal status 10 years post-allogeneic bone marrow transplantation
Gubrianska D; Machaczka M; Hassan M; Hagglund H; Ljungman P; Palmer M
Article: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2019;20(19):E4734-4734
Extracellular Albumin Covalently Sequesters Selenocompounds and Determines Cytotoxicity
Zheng W; Boada R; He R; Xiao T; Ye F; Simonelli L; Valiente M; Zhao Y; Hassan M
Article: TRANSPLANTATION AND CELLULAR THERAPY. 2019;25(9):1890-1897
Harmonization of Busulfan Plasma Exposure Unit (BPEU): A Community-Initiated Consensus Statement
McCune JS; Quinones CM; Ritchie J; Carpenter PA; van Maarseveen E; Yeh RF; Anasetti C; Boelens JJ; Hamerschlak N; Hassan M; Kang HJ; Kanda Y; Paci A; Perales M-A; Shaw PJ; Seewaldt VL; Savani BN; Hsieh A; Poon B; Mohty M; Pulsipher MA; Pasquini M; Dupuis LL
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2019;515(3):487-492
Degradation of pristine and oxidized single wall carbon nanotubes by CYP3A4
El-Sayed R; Waraky A; Ezzat K; Albabtain R; Eigammal K; Shityakov S; Muhammed M; Hassan M
Article: BEHAVIOURAL BRAIN RESEARCH. 2019;367:28-34
Sustained overexpression of neuropeptide S in the amygdala reduces anxiety-like behavior in rats
Tillmann S; Skibdal HE; Christiansen SH; Gotzsche CR; Hassan M; Mathe AA; Wegener G; Woldbye DPD
Article: APPLIED MATERIALS TODAY. 2019;15:267-279
Tracking stem cells and macrophages with gold and iron oxide nanoparticles - The choice of the best suited particles
Sun X; Gamal M; Nold P; Said A; Chakraborty I; Pelaz B; Schmied F; von Pueckler K; Figiel J; Zhao Y; Brendel C; Hassan M; Parak WJ; Feliu N
Article: SCIENTIFIC REPORTS. 2019;9(1):3903
CT Scanning and MATLAB Calculations for Preservation of Coptic Mural Paintings in Historic Egyptian Monasteries
Sallam A; Hemeda S; Toprak MS; Muhammed M; Hassan M; Uheida A
Article: FRONTIERS IN PHARMACOLOGY. 2019;10:481
CYP2J2*7 Genotype Predicts Risk of Chemotherapy-Induced Hematologic Toxicity and Reduced Relative Dose Intensity in Ethiopian Breast Cancer Patients
Ahmed JH; Makonnen E; Yimer G; Seifu D; Bekele A; Assefa M; Aseffa A; Howes R; Fotoohi A; Hassan M; Aklillu E
Article: BEHAVIOURAL BRAIN RESEARCH. 2018;351:93-103
Sex-dependent behavior, neuropeptide profile and antidepressant response in rat model of depression
Sanchez C; El Khoury A; Hassan M; Wegener G; Mathe AA
Article: ASIAN PACIFIC JOURNAL OF CANCER PREVENTION. 2018;19(8):2305-2311
miR-1266-5p and miR-185-5p Promote Cell Apoptosis in Human Prostate Cancer Cell Lines.
Ostadrahimi S; Abedi Valugerdi M; Hassan M; Haddad G; Fayaz S; Parvizhamidi M; Mahdian R; Fard Esfahani P
Article: JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY. 2018;46:482-489
Cold isostatic pressing of hydrating calcium sulfate as a means to produce parenteral slow-release drug formulations
Gruden S; Hassan M; Axen N
Article: SCIENTIFIC REPORTS. 2018;8(1):8293
The effect of N-acetyl-l-cysteine (NAC) on liver toxicity and clinical outcome after hematopoietic stem cell transplantation
El-Serafi I; Remberger M; El-Serafi A; Benkessou F; Zheng W; Martell E; Ljungman P; Mattsson J; Hassan M
Article: ONCOLOGY LETTERS. 2018;15(5):8157-8164
Downregulation of miR-1266-5P, miR-185-5P and miR-30c-2 in prostatic cancer tissue and cell lines
Ostadrahimi S; Fayaz S; Parvizhamidi M; Abedi-Valugerdi M; Hassan M; Kadivar M; Teimoori-Toolabi L; Asgari M; Shahrokh H; Abolhasani M; Mandian R; Fard-Esfahani P
Article: JOURNAL OF THEORETICAL BIOLOGY. 2018;442:1-10
Mathematical modeling of tumor-induced immunosuppression by myeloid-derived suppressor cells: Implications for therapeutic targeting strategies
Shariatpanahi SP; Shariatpanahi SP; Madjidzadeh K; Hassan M; Abedi-Valugerdi M
Article: NANO TODAY. 2018;18:103-123
Advances in nanotechnology for cancer biomarkers
Ye F; Zhao Y; Ei-Sayed R; Muhammed M; Hassan M
Article: JOURNAL OF CLINICAL APHERESIS. 2017;32(6):384-391
G-CSF mobilized peripheral blood stem cell collection for allogeneic transplantation in healthy donors: Analysis of factors affecting yield
Machaczka M; Hagglund H; Staver E; Joks M; Hassan M; Wahlin BE; Nygell UA
Article: INTERNATIONAL JOURNAL OF HEMATOLOGY. 2017;106(4):471-475
Toxicological effects of fludarabine and treosulfan conditioning before allogeneic stem-cell transplantation
Remberger M; Torlen J; El Serafi I; Garming-Legert K; Bjorklund A; Ljungman P; Sundin M; Hassan M; Mattsson J
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2017;491(1):15-18
Importance of the surface chemistry of nanoparticles on peroxidase-like activity
El-Sayed R; Ye F; Asem H; Ashour R; Zheng W; Muhammed M; Hassan M
Article: EXPERIMENTAL HEMATOLOGY. 2017;52:65-71
Development of an assay for cellular efflux of pharmaceutically active agents and its relevance to understanding drug interactions
Valdez BC; Hassan M; Andersson BS
Article: ANALYTICAL CHEMISTRY. 2017;89(14):7586-7592
Rapid and Robust Quantification of p-Xyleneselenocyanate in Plasma via Derivatization
Zheng W; Benkessou F; Twelkmeyer B; Wang S; Ginman T; Ottosson H; Abedi-Valugerdi M; Angels Subirana M; Zhao Y; Hassan M
Article: INTERNATIONAL IMMUNOPHARMACOLOGY. 2017;47:173-181
Differential effects of low-dose fludarabine or 5-fluorouracil on the tumor growth and myeloid derived immunosuppression status of tumor-bearing mice
Abedi-Valugerdi M; Zheng W; Benkessou F; Zhao Y; Hassan M
Article: PLOS ONE. 2017;12(11):e0187294
Flavin-containing monooxygenase 3 (FMO3) role in busulphan metabolic pathway
El-Serafi I; Terelius Y; Abedi-Valugerdi M; Naughton S; Saghafian M; Moshfegh A; Mattsson J; Potacova Z; Hassan M
Article: JOURNAL OF NANOBIOTECHNOLOGY. 2016;14(1):82
Biodistribution of biodegradable polymeric nano-carriers loaded with busulphan and designed for multimodal imaging
Asem H; Zhao Y; Ye F; Barrefelt A; Abedi-Valugerdi M; El-Sayed R; El-Serafi I; Abu-Salah KM; Hamm J; Muhammed M; Hassan M
Article: INTERNATIONAL IMMUNOPHARMACOLOGY. 2016;40:41-49
Suppressive effects of low-dose 5-fluorouracil, busulfan or treosulfan on the expansion of circulatory neutrophils and myeloid derived immunosuppressor cells in tumor-bearing mice
Abedi-Valugerdi M; Wolfsberger J; Pillai PR; Zheng W; Sadeghi B; Zhao Y; Hassan M
Article: TRANSPLANTATION AND CELLULAR THERAPY. 2016;22(11):1915-1925
Personalizing Busulfan-Based Conditioning: Considerations from the American Society for Blood and Marrow Transplantation Practice Guidelines Committee
Palmer J; McCune JS; Perales M-A; Marks D; Bubalo J; Mohty M; Wingard JR; Paci A; Hassan M; Bredeson C; Pidala J; Shah N; Shaughnessy P; Majhail N; Schriber J; Savani BN; Carpenter PA
Article: THE LANCET HAEMATOLOGY. 2016;3(11):e526-e536
Association of busulfan exposure with survival and toxicity after haemopoietic cell transplantation in children and young adults: a multicentre, retrospective cohort analysis
Bartelink IH; Lalmohamed A; van Reij EML; Dvorak CC; Savic RM; Zwaveling J; Bredius RGM; Egberts ACG; Bierings M; Kletzel M; Shaw PJ; Nath CE; Hempel G; Ansari M; Krajinovic M; Theoret Y; Duval M; Keizer RJ; Bittencourt H; Hassan M; Gungor T; Wynn RF; Veys P; Cuvelier GDE; Marktel S; Chiesa R; Cowan MJ; Slatter MA; Stricherz MK; Jennissen C; Long-Boyle JR; Boelens JJ
Article: PHOTODIAGNOSIS AND PHOTODYNAMIC THERAPY. 2016;13:48-57
Development and biodistribution of a theranostic aluminum phthalocyanine nanophotosensitizer
Asem H; Abd El-Fattah A; Nafee N; Zhao Y; Khalil L; Muhammed M; Hassan M; Kandil S
Article: PHARMACOGENOMICS JOURNAL. 2015;15(5):405-413
Cytochrome P450 2J2, a new key enzyme in cyclophosphamide bioactivation and a potential biomarker for hematological malignancies
El-Serafi I; Fares M; Abedi-Valugerdi M; Afsharian P; Moshfegh A; Terelius Y; Potacova Z; Hassan M
Article: CELL METABOLISM. 2015;22(3):408-417
Transplanted Bone Marrow-Derived Cells Contribute to Human Adipogenesis
Ryden M; Uzunel M; Hard JL; Borgstrom E; Mold JE; Arner E; Mejhert N; Andersson DP; Widlund Y; Hassan M; Jones CV; Spalding KL; Svahn B-M; Ahmadian A; Frisen J; Bernard S; Mattsson J; Arner P
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2015;464(3):737-742
Fluorescence labeled microbubbles for multimodal imaging
Barrefelt A; Zhao Y; Larsson MK; Egri G; Kuiper RV; Hamm J; Saghafian M; Caidahl K; Brismar TB; Aspelin P; Heuchel R; Muhammed M; Dahne L; Hassan M
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2015;463(3):268-274
DNA damage, lysosomal degradation and Bcl-xL deamidation in doxycycline- and minocycline-induced cell death in the K562 leukemic cell line
Fares M; Abedi-Valugerdi M; Hassan M; Potacova Z
Article: CHEMOSPHERE. 2015;129:225-231
Complement activation is involved in the hepatic injury caused by high-dose exposure of mice to perfluorooctanoic acid
Botelho SC; Saghafian M; Pavlova S; Hassan M; DePierre JW; Abedi-Valugerdi M
Article: CHRONOBIOLOGY INTERNATIONAL. 2015;32(5):608-614
The effect of circadian rhythm on pharmacokinetics and metabolism of the Cdk inhibitor, roscovitine, in tumor mice model
Sallam H; El-Serafi AT; Filipski E; Terelius Y; Levi F; Hassan M
Article: IMMUNOLOGY LETTERS. 2015;163(2):193-198
Immunotoxicological effects of streptozotocin and alloxan: In vitro and in vivo studies
Diab RAH; Fares M; Abedi-Valugerdi M; Kumagai-Braesch M; Holgersson J; Hassan M
Article: PLOS ONE. 2015;10(11):e0141979
Cytochrome P450 Oxidoreductase Influences CYP2B6 Activity in Cyclophosphamide Bioactivation
El-Serafi I; Afsharian P; Moshfegh A; Hassan M; Terelius Y
Article: ANTIMICROBIAL AGENTS AND CHEMOTHERAPY. 2014;58(8):4941-4943
Posaconazole Concentrations in Human Tissues after Allogeneic Stem Cell Transplantation
Blennow O; Eliasson E; Pettersson T; Pohanka A; Szakos A; El-Serafi I; Hassan M; Ringden O; Mattsson J
Article: NANO. 2014;9(6):1450069
DYNAMIC MR IMAGING, BIODISTRIBUTION AND PHARMACOKINETICS OF POLYMER SHELLED MICROBUBBLES CONTAINING SPION
Barrefelt A; Paradossi G; Asem H; Margheritelli S; Saghafian M; Oddo L; Muhammed M; Aspelin P; Hassan M; Brismar TB
Article: XENOTRANSPLANTATION. 2014;21(4):353-366
Rat islets are not rejected by anti-islet antibodies in mice treated with costimulation blockade
Diab RAH; Hassan M; Tibell A; Holgersson J; Kumagai-Braesch M
Article: LEUKEMIA AND LYMPHOMA. 2014;55(7):1618-1624
The nanoparticulate Quillaja saponin KGI exerts anti-proliferative eff ects by down-regulation of cell cycle molecules in U937 and HL-60 human leukemia cells
Berenjian S; Hu K; Abedi-Valugerdi M; Hassan M; Hassan SB; Morein B
Article: BIOMATERIALS. 2014;35(12):3885-3894
Biodegradable polymeric vesicles containing magnetic nanoparticles, quantum dots and anticancer drugs for drug delivery and imaging
Ye F; Barrefelt A; Asem H; Abedi-Valugerdi M; El-Serafi I; Saghafian M; Abu-Salah K; Alrokayan S; Muhammed M; Hassan M
Article: THE LANCET. 2014;383(9915):436-448
Reduced-intensity conditioning and HLA-matched haemopoietic stem-cell transplantation in patients with chronic granulomatous disease: a prospective multicentre study
Guengoer T; Teira P; Slatter M; Stuessi G; Stepensky P; Moshous D; Vermont C; Ahmad I; Shaw PJ; Telles da Cunha JM; Schlegel PG; Hough R; Fasth A; Kentouche K; Gruhn B; Fernandes JF; Lachance S; Bredius R; Resnick IB; Belohradsky BH; Gennery A; Fischer A; Gaspar HB; Schanz U; Seger R; Rentsch K; Veys P; Haddad E; Albert MH; Hassan M
Article: CLINICAL DRUG INVESTIGATION. 2014;34(1):43-52
Comparison of Algorithms for Oral Busulphan Area Under the Concentration-Time Curve Limited Sampling Estimate
Sjoo F; El-Serafi I; Enestig J; Mattsson J; Liwing J; Hassan M
Article: THERANOSTICS. 2014;4(6):604-613
Real-Time Assessment of Tissue Hypoxia In Vivo with Combined Photoacoustics and High-Frequency Ultrasound
Gerling M; Zhao Y; Nania S; Norberg KJ; Verbeke CS; Englert B; Kuiper RV; Bergstrom A; Hassan M; Neesse A; Lohr JM; Heuchel RL
Article: PLOS ONE. 2014;9(1):e86619
Cyclophosphamide Alters the Gene Expression Profile in Patients Treated with High Doses Prior to Stem Cell Transplantation
El-Serafi I; Abedi-Valugerdi M; Potacova Z; Afsharian P; Mattsson J; Moshfegh A; Hassan M
Article: BMC PHARMACOLOGY AND TOXICOLOGY. 2013;14:50
Pharmacokinetics and biodistribution of the cyclin-dependent kinase inhibitor-CR8-in mice
Sallam H; El-Serafi I; Meijer L; Hassan M
Article: BONE MARROW TRANSPLANTATION. 2013;48(6):843-848
Omega-3 from fish oil augments GVHD through the enhancement of chemotherapy conditioning regimen and selective FoxP3 depletion
Al Hashmi S; Sadeghi B; Hassan Z; Abedi-Valugerdi M; Lindskog M; Hassan M
Article: TOXICOLOGY LETTERS. 2013;219(1):1-7
Sub-acute, moderate-dose, but not short-term, low-dose dietary pre-exposure of mice to perfluorooctanoate aggravates concanavalin A-induced hepatitis
Qazi MR; Hassan M; Nelson BD; DePierre JW; Abedi-Valugerdi M
Article: PEDIATRIC TRANSPLANTATION. 2013;17(3):285-293
Increased risk of gastrointestinal acute GVHD following the addition of melphalan to busulfan/cyclophosphamide conditioning
Martensson T; Priftakis P; Casswall T; Ringden O; Mattsson J; Remberger M; Hassan M; Gustafsson B
Article: NANO LETTERS. 2013;13(4):1393-1398
Thermostable Luciferase from Luciola cruciate for Imaging of Carbon Nanotubes and Carbon Nanotubes Carrying Doxorubicin Using in Vivo Imaging System
El-Sayed R; Eita M; Barrefelt A; Ye F; Jain H; Fares M; Lundin A; Crona M; Abu-Salah K; Muhammed M; Hassan M
Article: EJNMMI RESEARCH. 2013;3(1):12
Multimodality imaging using SPECT/CT and MRI and ligand functionalized ^99mTc-labeled magnetic microbubbles
Barrefelt AA; Brismar TB; Egri G; Aspelin P; Olsson A; Oddo L; Margheritelli S; Caidahl K; Paradossi G; Daehne L; Axelsson R; Hassan M
Article: TOXICOLOGY LETTERS. 2013;217(1):67-74
Both sub-acute, moderate-dose and short-term, low-dose dietary exposure of mice to perfluorooctane sulfonate exacerbates concanavalin A-induced hepatitis
Qazi MR; Hassan M; Nelson BD; DePierre JW; Abedi-Valugerdi M
Article: BONE MARROW TRANSPLANTATION. 2013;48(2):284-293
Early-phase GVHD gene expression profile in target versus non-target tissues: kidney, a possible target?
Sadeghi B; Al-Chaqmaqchi H; Al-Hashmi S; Brodin D; Hassan Z; Abedi-Valugerdi M; Moshfegh A; Hassan M
Article: JOURNAL OF CHROMATOGRAPHY B: ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES. 2013;913:98-105
Gas chromatographic-mass spectrometry method for the detection of busulphan and its metabolites in plasma and urine
El-Serafi I; Terelius Y; Twelkmeyer B; Hagbjork A-L; Hassan Z; Hassan M
Article: INTERNATIONAL JOURNAL OF NANOMEDICINE. 2013;8:3241-3254
Biodistribution, kinetics, and biological fate of SPION microbubbles in the rat
Barrefelt A; Saghafian M; Kuiper R; Ye F; Egri G; Klickermann M; Brismar TB; Aspelin P; Muhammed M; Daehne L; Hassan M
Article: PLOS ONE. 2013;8(7):e68937
Activation of Wnt/β-Catenin Pathway in Monocytes Derived from Chronic Kidney Disease Patients
Al-Chaqmaqchi HAM; Moshfegh A; Dadfar E; Paulsson J; Hassan M; Jacobson SH; Lundahl J
Article: PLOS ONE. 2013;8(4):e60367
The Role of Programmed Cell Death Ligand-1 (PD-L1/CD274) in the Development of Graft versus Host Disease
Al-Chaqmaqchi H; Sadeghi B; Abedi-Valugerdi M; Al-Hashmi S; Fares M; Kuiper R; Lundahl J; Hassan M; Moshfegh A
Article: PLOS ONE. 2012;7(1):e30897
Busulphan-Cyclophosphamide Cause Endothelial Injury, Remodeling of Resistance Arteries and Enhanced Expression of Endothelial Nitric Oxide Synthase
Al-Hashmi S; Boels PJM; Zadjali F; Sadeghi B; Sallstrom J; Hultenby K; Hassan Z; Arner A; Hassan M
Article: NATURE MEDICINE. 2011;17(12):1636-1640
Inhibition of proteasome deubiquitinating activity as a new cancer therapy.
D'Arcy P; Brnjic S; Olofsson MH; Fryknäs M; Lindsten K; De Cesare M; Perego P; Sadeghi B; Hassan M; Larsson R; Linder S
Article: TRANSPLANTATION AND CELLULAR THERAPY. 2011;17(11):1688-1697
Improved Survival after Allogeneic Hematopoietic Stem Cell Transplantation in Recent Years. A Single-Center Study
Remberger M; Ackefors M; Berglund S; Blennow O; Dahllof G; Dlugosz A; Garming-Legert K; Gertow J; Gustafsson B; Hassan M; Hassan Z; Hauzenberger D; Hagglund H; Karlsson H; Klingspor L; Kumlien G; Le Blanc K; Ljungman P; Machaczka M; Malmberg K-J; Marschall H-U; Mattsson J; Olsson R; Omazic B; Sairafi D; Schaffer M; Svahn B-M; Svenberg P; Swartling L; Szakos A; Uhlin M; Uzunel M; Watz E; Wernerson A; Wikman A; Wikstrom A-C; Winiarski J; Ringden O
Article: ORAL DISEASES. 2011;17(7):670-676
Long-term salivary function after conditioning with busulfan, fractionated or single-dose TBI
Garming-Legert K; Remberger M; Ringden O; Hassan M; Dahllof G
Article: PEDIATRIC TRANSPLANTATION. 2011;15(6):580-588
Therapeutic drug monitoring is essential for intravenous busulfan therapy in pediatric hematopoietic stem cell recipients
Malaer R; Sjoo F; Rentsch K; Hassan M; Guengoer T
Article: INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL PATHOLOGY. 2011;4(6):596-605
Dynamics of early histopathological changes in GVHD after busulphan/cyclophosphamide conditioning regimen
Al-Hashmi S; Hassan Z; Sadeghi B; Rozell B; Hassan M
Article: SULTAN QABOOS UNIVERSITY MEDICAL JOURNAL. 2011;11(2):165-178
The Role of Pharmacokinetics and Pharmacodynamics in Early Drug Development with reference to the Cyclin-dependent Kinase (Cdk) Inhibitor - Roscovitine.
Hassan M; Sallam H; Hassan Z
Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 2011;41(4):1143-1153
N-acetyl-L-cysteine increases acute graft-versus-host disease and promotes T-cell-mediated immunity in vitro
Karlsson H; Nava S; Remberger M; Hassan Z; Hassan M; Ringden O
Article: CLINICAL AND DEVELOPMENTAL IMMUNOLOGY. 2010;2010:142943
Expansion and Activation Kinetics of Immune Cells during Early Phase of GVHD in Mouse Model Based on Chemotherapy Conditioning
Sadeghi B; Al-Hashmi S; Hassan Z; Rozell B; Concha H; Lundmark C; Gronvik K-O; Abedi-Valugerdi M; Hassan M
Article: CHRONOBIOLOGY INTERNATIONAL. 2009;26(8):1613-1621
CIRCADIAN VARIABILITY OF BILIRUBIN IN HEALTHY MEN DURING NORMAL SLEEP AND AFTER AN ACUTE SHIFT OF SLEEP
Larsson A; Hassan M; Ridefelt P; Axelsson J
Article: CHRONOBIOLOGY INTERNATIONAL. 2009;26(6):1169-1188
Liver Circadian Clock, a Pharmacologic Target of Cyclin-Dependent Kinase Inhibitor Seliciclib
Iurisci I; Filipski E; Sallam H; Harper F; Guettier C; Maire I; Hassan M; Iacobelli S; Levi F
Article: BONE MARROW TRANSPLANTATION. 2008;42(12):807-818
GVHD after chemotherapy conditioning in allogeneic transplanted mice
Sadeghi B; Aghdami N; Hassan Z; Forouzanfar M; Rozell B; Abedi-Valugerdi M; Hassan M
Article: MOLECULAR CANCER THERAPEUTICS. 2008;7(9):2713-2724
N-&-N, a new class of cell death-inducing kinase inhibitors derived from the purine roscovitine
Bettayeb K; Sallam H; Ferandin Y; Popowycz F; Fournet G; Hassan M; Echalier A; Bernard P; Endicott J; Joseph B; Meijer L
Article: TRANSPLANTATION. 2008;86(2):257-263
Evaluation of immune responses to seasonal influenza vaccination in healthy volunteers and in patients after stem cell transplantation
Avetisyan G; Aschan J; Hassan M; Ljungman P
Article: PHARMACOLOGICAL RESEARCH. 2008;58(1):32-37
Age-dependent pharmacokinetics and effect of roscovitine on Cdk5 and Erk1/2 in the rat brain
Sallam H; Jimenez P; Song H; Vita M; Cedazo-Minguez A; Hassan M
Article: NATURE. 2008;453(7196):783-787
Dynamics of fat cell turnover in humans
Spalding KL; Arner E; Westermark PO; Bernard S; Buchholz BA; Bergmann O; Blomqvist L; Hoffstedt J; Naslund E; Britton T; Concha H; Hassan M; Ryden M; Frisen J; Arner P
Article: BONE MARROW TRANSPLANTATION. 2008;41(10):895-904
The effect of administration order of BU and CY on engraftment and toxicity in HSCT mouse model
Sadeghi B; Jansson M; Hassan Z; Mints M; Hagglund H; Abedi-Valugerdi M; Hassan M
Article: BONE MARROW TRANSPLANTATION. 2008;41(9):785-790
A prospective randomized study using N-acetyl-L-cysteine for early liver toxicity after allogeneic hematopoietic stem cell transplantation
Barkholt L; Remberger M; Hassan Z; Fransson K; Omazic B; Svahn B-M; Karlsson H; Brune M; Hassan M; Mattsson J; Ringden O
Article: BONE MARROW TRANSPLANTATION. 2008;41(7):621-625
Safe administration of oral BU twice daily during conditioning for stem cell transplantation in a paediatric population:: A comparative study between the standard 4-dose and a 2-dose regimen
Mellgren K; Nilsson C; Fasth A; Abrahamsson J; Winiarski J; Ringden O; Hassan M
Article: JOURNAL OF LIQUID CHROMATOGRAPHY AND RELATED TECHNOLOGIES. 2008;31(5):683-694
Rapid and sensitive method for determination of cyclophosphamide in patients plasma samples utilizing microextraction by packed sorbent online with liquid chromatography-tandem mass spectrometry (MEPS-LC-MS/MS)
Said R; Hassan Z; Hassan M; Abdel-Rehim M
Article: EXPERIMENTAL HEMATOLOGY. 2008;36(2):149-157
Hypomethylation and apoptosis in 5-azacytidine-treated myeloid cells
Khan R; Schmidt-Mende J; Karim M; Gogvadze V; Hassan M; Ekstrom TJ; Zhivotovsky B; Hellstrom-Lindberg E
Article: HUMAN REPRODUCTION. 2008;23(1):139-143
Endometrial endothelial cells are derived from donor stem cells in a bone marrow transplant recipient
Mints M; Jansson M; Sadeghi B; Westgren M; Uzunel M; Hassan M; Palmblad J
Article: THERAPEUTIC DRUG MONITORING. 2007;29(5):626-631
Higher plasma but not intracellular concentrations after infusion with liposomal daunorubicin compared with conventional daunorubicin in adult acute myeloid leukemia
Lofgren C; Lehmann S; Jonsson-Videsater K; Mollgard L; Linder O; Tidefelt U; Hassan M; Paul C
Article: JOURNAL OF LIQUID CHROMATOGRAPHY AND RELATED TECHNOLOGIES. 2007;30(20):3029-3041
Simultaneous determination of busulphan in plasma samples by liquid chromatography-electrospray ionization mass spectrometry utilizing microextraction in packed syringe (MEPS) as on-line sample preparation method
Abdel-Rehim M; Hassan Z; Skansem P; Hassan M
Article: CLINICAL CANCER RESEARCH. 2007;13(14):4218-4224
The effect of repeated administration of cyclophosphamide on cytochrome P4502B in rats
Afsharian P; Zuzana YT; Hassan Z; Nilsson C; Lundgren S; Hassan M
Article: BONE MARROW TRANSPLANTATION. 2006;38(10):687-692
Impact on the cytomegalovirus (CMV) viral load by CMV-specific T-cell immunity in recipients of allogeneic stem cell transplantation
Avetisyan G; Larsson K; Aschan J; Nilsson C; Hassan M; Ljungman P
Article: NATURE MEDICINE. 2006;12(4):401-409
Correction of X-linked chronic granulomatous disease by gene therapy, augmented by insertional activation of MDS1-EVI1, PRDM16 or SETBP1
Ott MG; Schmidt M; Schwarzwaelder K; Stein S; Siler U; Koehl U; Glimm H; Kühlcke K; Schilz A; Kunkel H; Naundorf S; Brinkmann A; Deichmann A; Fischer M; Ball C; Pilz I; Dunbar C; Du Y; Jenkins NA; Copeland NG; Lüthi U; Hassan M; Thrasher AJ; Hoelzer D; von Kalle C; Seger R; Grez M
Article: BASIC AND CLINICAL PHARMACOLOGY AND TOXICOLOGY. 2006;98(2):197-200
Inhibitory effect of 5-fluorouracil on cytochrome P4502C9 activity in cancer patients
Gunes A; Coskun U; Boruban C; Gunel N; Babaoglu MO; Sencan O; Bozkurt A; Rane A; Hassan M; Zengil H; Yasar U
Article: EXPERIMENTAL HEMATOLOGY. 2006;34(1):115-121
Myeloablative and immunosuppressive properties of treosulfan in mice
Sjöö F; Hassan Z; Abedi-Valugerdi M; Griskevicius L; Nilsson C; Remberger M; Aschan J; Concha H; Gaughan U; Hassan M
Article: EXPERIMENTAL HEMATOLOGY. 2006;34(1):35-43
Pharmacodynamic study of 5-azacytidine in the P39 cell line
Khan R; Aggerholm A; Hokland P; Hassan M; Hellström-Lindberg E
Article: EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES. 2006;27(1):54-61
Pharmacogenetics of cyclophosphamide in patients with hematological malignancies
Xie HJ; Griskevicius L; Ståhle L; Hassan Z; Yasar Ü; Rane A; Broberg U; Kimby E; Hassan M
Article: BONE MARROW TRANSPLANTATION. 2005;36(5):411-415
Cell-mediated immune responses to influenza vaccination in healthy volunteers and allogeneic stem cell transplant recipients
Avetisyan G; Ragnavölgyi E; Toth GT; Hassan M; Ljungman P
Article: EUROPEAN JOURNAL OF HAEMATOLOGY. 2005;75(3):206-211
The effect of ciprofloxacin on cyclophosphamide pharmacokinetics in patients with non-Hodgkin lymphoma
Afsharian P; Möllgård L; Hassan Z; Xie HJ; Kimby E; Hassan M
Article: JOURNAL OF CHROMATOGRAPHY B: ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES. 2005;821(1):75-80
Stability, pKa and plasma protein binding of roscovitine
Vita M; Abdel-Rehim M; Nilsson C; Hassan Z; Skansen P; Wan H; Meurling L; Hassan M
Article: CLINICAL AND EXPERIMENTAL IMMUNOLOGY. 2005;141(2):238-247
Bacterial lipopolysaccharide both renders resistant mice susceptible to mercury-induced autoimmunity and exacerbates such autoimmunity in susceptible mice
Abedi-Valugerdi M; Nilsson C; Zargari A; Gharibdoost F; DePierre JW; Hassan M
Article: TRANSPLANTATION. 2005;79(11):1607-1614
Fetal mesenchymal stem-cell engraftment in bone after in utero transplantation in a patient with severe osteogenesis imperfecta
Le Blanc K; Götherström C; Ringdén O; Hassan M; McMahon R; Horwitz E; Anneren G; Axelsson O; Nunn J; Ewald U; Nordén-Lindeberg S; Jansson M; Dalton A; Åström E; Westgren M
Article: EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES. 2005;25(1):91-103
Tissue distribution, pharmacokinetics and identification of roscovitine metabolites in rat
Vita M; Abdel-Rehim M; Olofsson S; Hassan Z; Meurling L; Sidén Å; Sidén M; Pettersson T; Hassan M
Article: ANALYTICA CHIMICA ACTA. 2005;539(1-2):35-39
Microextraction in packed syringe/liquid chromatography/electrospray tandem mass spectrometry for quantification of olomoucine in human plasma samples
Abdel-Rehim M; Skansen P; Vita M; Hassan Z; Blomberg L; Hassan M
Article: JOURNAL OF CHROMATOGRAPHY B: ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES. 2005;817(2):303-307
Development and validation of a liquid chromatography and tandem mass spectrometry method for determination of roscovitine in plasma and urine samples utilizing on-line sample preparation
Vita M; Skansen P; Hassan M; Abdel-Rehim M
Article: EXPERIMENTAL HEMATOLOGY. 2005;33(3):380-387
Effect of altering administration order of busulphan and cyclophosphamide on the myeloablative and immunosuppressive properties of the conditioning regimen in mice
Nilsson C; Forsman J; Hassan Z; Abedi-Valugerdi M; O'Connor C; Concha H; Jansson M; Hassan M
Article: IMMUNOLOGY. 2005;114(3):428-437
Exposure to mercuric chloride during the induction phase and after the onset of collagen-induced arthritis enhances immune/autoimmune responses and exacerbates the disease in DBA/1 mice
Hansson M; Djerbi M; Rabbani H; Mellstedt H; Gharibdoost F; Hassan M; DePierre JW; Abedi-Valugerdi M
Article: XENOBIOTICA. 2005;35(3):239-251
Cyclophosphamide induces mRNA, protein and enzyme activity of cytochrome P450 in rat
Xie H; Afsharian P; Terelius Y; Mirghani RA; Yasar Ü; Hagbjörk AL; Lundgren S; Hu Y; Rane A; Hassan M
Article: TRANSPLANTATION. 2004;78(1):154-157
Lung epithelial cells and type II pneumocytes of donor origin after allogeneic hematopoietic stem cell transplantation
Mattson J; Jansson M; Wernerson A; Hassan M
Article: THE LANCET. 2004;363(9419):1439-1441
Treatment of severe acute graft-versus-host disease with third party haploidentical mesenchymal stem cells
Le Blanc K; Rasmusson I; Sundberg B; Götherström C; Hassan M; Uzunel M; Ringdén O
Article: JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS. 2004;34(2):425-431
Analysis of roscovitine using novel high performance liquid chromatography and UV-detection method:: pharmacokinetics of roscovitine in rat
Vita M; Meurling L; Pettersson T; Cruz-Sidén M; Sidén Å; Hassan M
Article: BONE MARROW TRANSPLANTATION. 2003;32(5):477-483
Fractionated TBI correlates with less T cell mixed chimerism but increased risk of relapse compared to busulphan in patients with haematological malignancies after allogeneic stem cell transplantation
Mattsson J; Uzunel M; Remberger M; Hassan M
Article: BONE MARROW TRANSPLANTATION. 2003;32(4):349-354
N-acetyl-L-cysteine does not affect the pharmacokinetics or myelosuppressive effect of busulfan during conditioning prior to allogeneic stem cell transplantation
Sjöö F; Aschan J; Barkholt L; Hassan Z; Ringdén O; Hassan M
Article: CLINICAL CANCER RESEARCH. 2003;9(7):2447-2456
Immunization of colorectal carcinoma patients with a recombinant Canarypox virus expressing the tumor antigen Ep-CAM/KSA (ALVAC-KSA) and granulocyte macrophage colonystimulating factor induced a tumor-specific cellular immune response
Ullenhag GJ; Frödin JE; Mosolits S; Kiaii S; Hassan M; Bonnet MC; Moingeon P; Mellstedt H; Rabbani H
Article: THERAPEUTIC DRUG MONITORING. 2003;25(3):400-406
On-line derivatization utilizing solid-phase microextraction (SPME) for determination of busulphan in plasma using gas chromatography-mass spectrometry (GC-MS)
Abdel-Rehim M; Hassan Z; Blomberg L; Hassan M
Article: EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY. 2003;59(2):103-109
Bioactivation of cyclophosphamide:: the role of polymorphic CYP2C enzymes
Griskevicius L; Yasar Ü; Sandberg M; Hidestrand M; Eliasson E; Tybring G; Hassan M; Dahl ML
Article: BONE MARROW TRANSPLANTATION. 2003;31(6):429-435
The effect of metronidazole on busulfan pharmacokinetics in patients undergoing hematopoietic stem cell transplantation
Nilsson C; Aschan J; Hentschke P; Ringdén O; Ljungman P; Hassan M
Article: BONE MARROW TRANSPLANTATION. 2003;31(3):197-203
Alteration of pharmacokinetics of cyclophosphamide and suppression of the cytochrome P450 genes by ciprofloxacin
Xie HJ; Griskevicius L; Broberg U; Lundgren S; Carlens S; Meurling L; Paul C; Rane A; Hassan M
Article: PHARMACOGENOMICS JOURNAL. 2003;3(1):53-61
Role of polymorphic human CYP2B6 in cyclophosphamide bioactivation
Xie HJ; Yasar Ü; Lundgren S; Griskevicius L; Terelius Y; Hassan M; Rane A
Article: BONE MARROW TRANSPLANTATION. 2002;30(12):833-841
A phase II trial of liposomal busulphan as an intravenous myeloablative agent prior to stem cell transplantation:: 500 mg/m² as a optimal total dose for conditioning
Hassan M; Nilsson C; Hassan Z; Gungor T; Aschan J; Winiarski J; Hentschke P; Ringdén O; Eber S; Seger R; Ljungman P
Article: EUROPEAN JOURNAL OF PHARMACOLOGY. 2002;449(3):197-205
Effect of cyclophosphamide on gene expression of cytochromes P450 and β-actin in the HL-60 cell line
Xie HJ; Lundgren S; Broberg U; Finnström N; Rane A; Hassan M
Article: BONE MARROW TRANSPLANTATION. 2002;30(3):141-147
The effect of modulation of glutathione cellular content on busulphan-induced cytotoxicity on hematopoietic cells in vitro and in vivo
Hassan Z; Hellström-Lindberg E; Alsadi S; Edgren M; Hägglund H; Hassan M
Article: THERAPEUTIC DRUG MONITORING. 2002;24(3):405-409
Simple method based on fluorescent detection for the determination of 4-hydroxycyclophosphamide in plasma
Griskevicius L; Meurling L; Hassan M
Article: BRITISH JOURNAL OF CANCER. 2001;85(12):2004-2009
Bioavailability and dose-dependent anti-tumour effects of 9-cis retinoic acid on human neuroblastoma xenografts in rat
Ponthan F; Kogner P; Bjellerup P; Klevenvall L; Hassan M
Article: BONE MARROW TRANSPLANTATION. 2001;28(7):657-664
Population pharmacokinetic analysis resulting in a tool for dose individualization of busulphan in bone marrow transplantation recipients
Sandström M; Karlsson MO; Ljungman P; Hassan Z; Jonsson EN; Nilsson C; Ringden O; Öberg G; Bekassy A; Hassan M
Article: LEUKEMIA. 2001;15(8):1240-1247
The pharmacodynamic effect of busulfan in the P39 myeloid cell line in vitro
Hassan Z; Hassan M; Hellström-Lindberg E
Article: CLINICAL CANCER RESEARCH. 2001;7(5):1163-1170
Alteration of interleukin 2 (IL-2) pharmacokinetics and function by IL-2 antibodies induced after treatment of colorectal carcinoma patients with a combination of monoclonal antibody 17-1A, granulocyte macrophage colony-stimulating factor, and IL-2
Skog ALH; Wadhwa M; Hassan M; Gharizadeh B; Bird C; Ragnhammar P; Thorpe R; Mellstedt H
Article: BONE MARROW TRANSPLANTATION. 2001;27(5):479-485
Pharmacokinetics of liposomal busulphan in man
Hassan Z; Ljungman P; Ringdén O; Winiarski J; Nilsson C; Aschan J; Whitley HR; Hassan M
Article: JOURNAL OF LIPID RESEARCH. 2001;42(1):70-78
Evidence that the major oxysterols in human circulation originate from distinct pools of cholesterol:: a stable isotope study
Meaney S; Hassan M; Sakinis A; Lütjohann D; von Bergmann K; Wennmalm Å; Diczfalusy U; Björkhem I
Article: LEUKEMIA. 2000;14(11):1954-1959
A phase I/II study of multiple-dose intravenous busulfan as myeloablation prior to stem cell transplantation
Olavarria E; Hassan M; Eades A; Nilsson C; Timms A; Matthews J; Craddock C; Kanfer E; Apperley J; Goldman J
Article: THERAPEUTIC DRUG MONITORING. 2000;22(4):383-385
Ketobemidone may alter busulfan pharmacokinetics during high-dose therapy
Hassan M; Svensson JO; Nilsson C; Hentschke P; AL-Shurbaji A; Aschan J; Ljungman P; Ringdén O
Article: BONE MARROW TRANSPLANTATION. 2000;25(9):915-924
The effect of busulphan on the pharmacokinetics of cyclophosphamide and its 4-hydroxy metabolite:: time interval influence on therapeutic efficacy and therapy-related toxicity
Hassan M; Ljungman P; Ringdén O; Hassan Z; Öberg G; Nilsson C; Békassy A; Bielenstein M; Abdel-Rehim M; Georén S; Astner L
Article: JOURNAL OF SEPARATION SCIENCE. 2000;23(2):156-157
Capillary gas chromatography of trichlorophenols using ammonia as carrier gas
Abdel-Rehim M; Hassan M
Article: NUCLEAR MEDICINE AND BIOLOGY. 1999;26(8):931-936
Biodistribution of liposomal ¹³¹I-VIP in rat using gamma camera
Refai E; Jonsson C; Andersson M; Jacobsson H; Larsson S; Kogner P; Hassan M
Article: BRITISH JOURNAL OF CLINICAL PHARMACOLOGY. 1999;48(5):669-677
A mechanism-based pharmacokinetic-enzyme model for cyclophosphamide autoinduction in breast cancer patients
Hassan M; Svensson USH; Ljungman P; Björkstrand B; Olsson H; Bielenstein M; Abdel-Rehim M; Nilsson C; Johansson M; Karlsson MO
Article: EUROPEAN JOURNAL OF HAEMATOLOGY. 1999;63(3):163-170
The influence of interferon-α on the pharmacokinetics of cyclophosphamide and its 4-hydroxy metabolite in patients with multiple myeloma
Hassan M; Nilsson C; Olsson H; Lundin J; Österborg A
Article: NUCLEAR MEDICINE AND BIOLOGY. 1999;26(4):413-420
In vivo dynamic distribution of ¹³¹I-glucagon-like peptide-1 (7-36) amide in the rat studied by gamma camera
Hassan M; Eskilsson A; Nilsson C; Jonsson C; Jacobsson H; Refai E; Larsson S; Efendic S
Article: LIFE SCIENCES. 1999;65(2):165-174
In vivo evaluation of the biodistribution of ¹¹C-labeled PD153035 in rats without and with neuroblastoma implants
Fredriksson A; Johnström P; Thorell JO; von Heijne G; Hassan M; Eksborg S; Kogner P; Borgström P; Ingvar M; Stone-Elander S
Article: BONE MARROW TRANSPLANTATION. 1998;22(9):913-918
Liposomal busulphan: bioavailability and effect on bone marrow in mice
Hassan Z; Nilsson C; Hassan M
Article: CANCER CHEMOTHERAPY AND PHARMACOLOGY. 1998;42(6):471-478
Pharmacokinetics and distribution of liposomal busulfan in the rat:: a new formulation for intravenous administration
Hassan M; Hassan Z; Nilsson C; Rehim MA; Kumlien S; Elfsson B; Kållberg N
Article: BONE MARROW TRANSPLANTATION. 1997;20(11):909-913
High busulfan concentrations are associated with increased transplant-related mortality in allogeneic bone marrow transplant patients
Ljungman P; Hassan M; Bekassy AN; Ringden O; Oberg G
Article: BONE MARROW TRANSPLANTATION. 1996;18(5):843-850
Busulphan kinetics and limited sampling model in children with leukemia and inherited disorders
Hassan M; Fasth A; Gerritsen B; Haraldsson A; Syruckova Z; vandenBerg H; Sandstrom M; Karlsson M; Kumlien S; Vossen J
Article: PEDIATRIC HEMATOLOGY AND ONCOLOGY. 1996;13(2):143-150
Infection-associated hemophagocytic syndrome complicated by infectious lymphoproliferation: A case report
Syruckova Z; Stary J; Sedlacek P; Smisek P; Vavrinec J; Komrska V; Roubalova K; Vandasova J; Sintakova B; Houskova J; Hassan M
Article: JOURNAL OF SEPARATION SCIENCE. 1996;8(2):151-156
Enantiomer separation of underivatized tocainide and related compounds by CGC using ammonia as carrier gas
AbdelRehim M; Karlen A; Zhang L; Kamel M; Hassan M
Article: JOURNAL OF SEPARATION SCIENCE. 1995;18(12):757-759
Effect of ammonia on the response of the electron capture detector (ECD)
AbdelRehim M; Kamel M; Hassan M
Article: EUROPEAN JOURNAL OF DRUG METABOLISM AND PHARMACOKINETICS. 1995;20(3):225-232
KINETICS AND METABOLISM OF 2-CHLORO-2'-DEOXYADENOSINE AND 2-CHLORO-2'-ARABINO-FLUORO-2'-DEOXYADENOSINE IN THE ISOLATED-PERFUSED RAT-LIVER
ALBERTIONI F; HASSAN M; SILBERRING J; LILIEMARK J
Article: BONE MARROW TRANSPLANTATION. 1995;15(6):869-871
BUSULFAN CONCENTRATION IN RELATION TO PERMANENT ALOPECIA IN RECIPIENTS OF BONE-MARROW TRANSPLANTS
LJUNGMAN P; HASSAN M; BEKASSY AN; RINGDEN O; OBERG G
Article: INTERNATIONAL PSYCHOGERIATRICS. 1995;7(1):75-83
One year on tacrine (THA): clinical and biochemical effects in patients with dementia of the Alzheimer type.
Ahlin A; Junthé T; Hassan M; Nybäck H
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Review: BONE MARROW TRANSPLANTATION. 2024;59(12):1-13
A practical guide to therapeutic drug monitoring in busulfan: recommendations from the Pharmacist Committee of the European Society for Blood and Marrow Transplantation (EBMT)
Domingos V; Nezvalova-Henriksen K; Dadkhah A; Moreno-Martinez M-E; Ben Hassine K; Pires V; Kroeger N; Bauters T; Hassan M; Duncan N; Kalwak K; Ansari M; Langebrake C; Admiraal R
Corrigendum: CELLS. 2024;13(17):1456
Rhenium Perrhenate (¹⁸⁸ReO4) Induced Apoptosis and Reduced Cancerous Phenotype in Liver Cancer Cells (vol 11, 305, 2022)
Asadian S; Piryaei A; Gheibi N; Kalantari BA; Davarpanah MR; Azad M; Kapustina V; Alikhani M; Nejad SM; Alikhani HK; Mohamadi M; Shpichka A; Timashev P; Hassan M; Vosough M
Review: SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY. 2024;59(5):623-629
Bioengineering vascularized liver tissue for biomedical research and application
Davoodi P; Rezaei N; Hassan M; Hay DC; Vosough M
Review: DRUG DEVELOPMENT RESEARCH. 2024;85(3):e22189
Chitosan-coated nanoparticles in innovative cancer bio-medicine
Rezaei N; Zarkesh I; Fotouhi A; Alikhani HK; Hassan M; Vosough M
Review: CELL JOURNAL. 2024;26(2):98-111
Review on Kidney-Liver Crosstalk: Pathophysiology of Their Disorders
Rad NK; Heydari Z; Tamimi AH; Zahmatkesh E; Shpichka A; Barekat M; Timashev P; Hossein-khannazer N; Hassan M; Vosough M
Review: FRONTIERS IN ONCOLOGY. 2024;14:1377761
P53/NANOG balance; the leading switch between poorly to well differentiated status in liver cancer cells
Ranjbar-Niavol F; Rezaei N; Zhao Y; Mirzaei H; Hassan M; Vosough M
Editorial comment: CELL JOURNAL. 2023;25(10):738-740
A Shadow of Knowledge in Stem Cell Science
Omid-Shafiei S; Hassan M; Nussler AK; Najimi M; Vosough M
Review: CELLS. 2023;12(18):2260
Circulating Tumor Cells as a Promising Tool for Early Detection of Hepatocellular Carcinoma
Salehi M; Lavasani ZM; Alikhani HK; Shokouhian B; Hassan M; Najimi M; Vosough M
Review: CELL JOURNAL. 2023;25(5):281-290
Platelet-Rich Plasma in Regenerative Medicine: Possible Applications in Management of Burns and Post-Burn Scars: A Review
Hosseini MS; Nouri M; Zarrabi M; Fatemi MJ; Shpichka A; Timashev P; Hassan M; Vosough M
Review: BIOMEDICINE & PHARMACOTHERAPY. 2023;161:114487
Autophagy orchestrates resistance in hepatocellular carcinoma cells
Seydi H; Nouri K; Rezaei N; Tamimi A; Hassan M; Mirzaei H; Vosough M
Review: BIOMEDICAL MATERIALS (BRISTOL). 2023;18(3):032001
Progress and promise of cell sheet assisted cardiac tissue engineering in regenerative medicine
Abdolahzadeh H; Rad NK; Shpichka A; Golroo R; Rahi K; Timashev P; Hassan M; Vosough M
Review: EXPERT REVIEW OF GASTROENTEROLOGY AND HEPATOLOGY. 2023;17(3):237-249
Cell and cell-derivative-based therapy for liver diseases: current approaches and future promises
Zahmatkesh E; Rad NK; Hossein-Khannazer N; Mohamadnejad M; Gramignoli R; Najimi M; Malekzadeh R; Hassan M; Vosough M
Review: JOURNAL OF CELLULAR PHYSIOLOGY. 2022;237(11):3984-4000
Hepatogenesis and hepatocarcinogenesis: Alignment of the main signaling pathways
Shokouhian B; Es HA; Negahdari B; Tamimi A; Shahdoust M; Shpichka A; Timashev P; Hassan M; Vosough M
Review: JOURNAL OF PERSONALIZED MEDICINE. 2022;12(11):1797
Cardiovascular Complications in Hematopoietic Stem Cell Transplanted Patients
Zhao Y; He R; Oerther S; Zhou W; Vosough M; Hassan M
Review: MOLECULAR BIOLOGY REPORTS. 2022;49(2):1545-1549
Mini review ATF4 and GRP78 as novel molecular targets in ER-Stress modulation for critical COVID-19 patients
Shahriari-Felordi M; Alikhani HK; Hashemian S-MR; Hassan M; Vosough M
Editorial comment: EXPERT REVIEW OF GASTROENTEROLOGY AND HEPATOLOGY. 2022;16(1):1-3
COVID-19 and hygiene hypothesis: increment of the inflammatory bowel diseases in next generation?
Shahrbaf MA; Hassan M; Vosough M
Review: FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY. 2022;10:894800
Regulatory Non-Coding RNAs in Familial Hypercholesterolemia, Theranostic Applications
Alikhani HK; Pourhamzeh M; Seydi H; Shokoohian B; Hossein-khannazer N; Jamshidi-adegani F; Al-Hashmi S; Hassan M; Vosough M
Review: JOURNAL OF CELLULAR AND MOLECULAR MEDICINE. 2021;25(18):8602-8614
Advanced therapeutic modalities in hepatocellular carcinoma: Novel insights
Shokoohian B; Negahdari B; Es HA; Abedi-Valugerdi M; Baghaei K; Agarwal T; Maiti TK; Hassan M; Najimi M; Vosough M
Review: PHARMACOLOGY AND THERAPEUTICS. 2021;220:107714
Novel molecular targets in gastric adenocarcinoma
Ramezankhani R; Solhi R; Es HA; Vosough M; Hassan M
Review: ACS NANO. 2021;15(3):3754-3807
X-ray-Based Techniques to Study the Nano-Bio Interface
Sanchez-Cano C; Alvarez-Puebla RA; Abendroth JM; Beck T; Blick R; Cao Y; Caruso F; Chakraborty I; Chapman HN; Chen C; Cohen BE; Conceicao ALC; Cormode DP; Cui D; Dawson KA; Falkenberg G; Fan C; Feliu N; Gao M; Gargioni E; Glueer C-C; Gruener F; Hassan M; Hu Y; Huang Y; Huber S; Huse N; Kang Y; Khademhosseini A; Keller TF; Koernig C; Kotov NA; Koziej D; Liang X-J; Liu B; Liu S; Liu Y; Liu Z; Liz-Marzan LM; Ma X; Machicote A; Maison W; Mancuso AP; Megahed S; Nickel B; Otto F; Palencia C; Pascarelli S; Pearson A; Penate-Medina O; Qi B; Raedler J; Richardson JJ; Rosenhahn A; Rothkamm K; Rubhausen M; Sanyal MK; Schaak RE; Schlemmer H-P; Schmidt M; Schmutzler O; Schotten T; Schulz F; Sood AK; Spiers KM; Staufer T; Stemer DM; Stierle A; Sun X; Tsakanova G; Weiss PS; Weller H; Westermeier F; Xu M; Yan H; Zeng Y; Zhao Y; Zhao Y; Zhu D; Zhu Y; Parak WJ
Review: FRONTIERS IN MICROBIOLOGY. 2021;12:785856
Application of Stem Cell-Derived Extracellular Vesicles as an Innovative Theranostics in Microbial Diseases
Alikhani HK; Shokoohian B; Rezasoltani S; Hossein-Khannazer N; Yadegar A; Hassan M; Vosough M
Editorial comment: TRANSPLANTATION AND CELLULAR THERAPY. 2020;26(9):e235-e236
Response to Kawedia et al Letter to Editor in Response to the Article by McCune Et Al ''Harmonization of Busulfan Plasma Exposure Unit (BPEU): A Community-Initiated Consensus Statement''
Dupuis LL; Quinones CM; Ritchie J; Carpenter PA; Bauters T; Yeh RF; Anasetti C; Boelens JJ; Hamerschlak N; Hassan M; Kang HJ; Kanda Y; Paci A; Perales M-A; Shaw PJ; Seewaldt VL; Savani BN; Militano O; Pulsipher MA; McCune JS
Editorial comment: FRONTIERS IN NEUROANATOMY. 2016;10:14
Commentary: Impact of a deletion of the full-length and short isoform of p75NTR on cholinergic innervation and the population of postmitotic doublecortin positive cells in the dentate gyrus
Sabry MA; Fares M; Folkesson R; Al-Ramadan M; Alabkal J; Al-Kafaji G; Hassan M
Editorial comment: HAEMATOLOGICA. 2014;99(7):1124-1127
Hematologic malignancies in elderly patients
Hassan M; Abedi-Valugerdi M
Review: PHARMACOGENOMICS. 2013;14(1):75-87
Role of pharmacogenetics in busulfan/cyclophosphamide conditioning therapy prior to hematopoietic stem cell transplantation
Hassan M; Andersson BS
Meeting abstract: TRANSPLANTATION AND CELLULAR THERAPY. 2011;17(2):S345
DYNAMICS OF DONOR T CELL ACTIVATION DURING EARLY PHASE OF GRAFT VERSUS HOST DISEASE (GVHD): DONOR ANTIGEN PRESENTING CELLS CAN ACTIVATE ALLOGENEIC T CELLS
Sadeghi B; Al-Hashmi S; Hassan Z; Hassan M
Meeting abstract: TRANSPLANTATION AND CELLULAR THERAPY. 2009;15(2):127
N-ACETYL-L-CYSTEINE PROMOTES T CELL MEDIATED IMMUNITY IN ALLOGENEIC SETTINGS IN VIVO AND IN VITRO
Karlsson H; Nava S; Remberger M; Hassan Z; Hassan M; Ringden O
Meeting abstract: LEUKEMIA RESEARCH. 2007;31:S62-S63
Hypomethylation and apoptosis in 5-azacytidine treated myeloid cells
Khan R; Schmidt-Mende J; Karimi M; Forsblom A-M; Gogvadze V; Hassan M; Ekstrom TJ; Zhivotovsky B; Hellstrom-Lindberg E
Meeting abstract: TRANSPLANTATION AND CELLULAR THERAPY. 2007;13(2):70-71
The role of human CYP2B6 polymorphism in the bioactivation of cyclophosphamide using CDNA expressed enzymes
Afsharian P; Teredius Y; Hidestrand M; Ingelman-Sundberg M; Hassan M; Lundgren S
Meeting abstract: BLOOD. 2006;108(11):97A
Effect of busulphan dose adjustment on regimen-related toxicity.
Hassan Z; Remberger M; Ringden O; Oberg G; Bekassy AN; Hassan M
Meeting abstract: BLOOD. 2005;106(11):193B
The effect of repeated administration of cyclophosphamide on CYP2B1 and 2B2 in rat.
Afsharian P; Terelius Y; Lundgren S; Hassan M
Meeting abstract: BLOOD. 2005;106(11):60A
Long-term follow-up of patients treated by gene therapy for X-linked chronic granulomatous disease.
Ott MG; Grez M; Stein S; Siler U; Koehl U; Kuehlcke K; Schmidt M; Schilz A; Kunkel H; Naundorf S; Brinkmann A; Hassan M; von Kalle C; Trasher A; Seger R; Hoelzer D
Published conference paper: PEDIATRIC BLOOD AND CANCER. 2001;36(1):127-131
The vitamin A analogues:: 13-cis retinoic acid, 9-cis retinoic acid, and Ro 13-6307 inhibit neuroblastoma tumour growth in vivo
Ponthan F; Borgström P; Hassan M; Wassberg E; Redfern CPF; Kogner P
Published conference paper: PEDIATRIC RESEARCH. 1999;46(3):328-332
The somatostatin analogue octreotide inhibits neuroblastoma growth in vivo
Borgström P; Hassan M; Wassberg E; Refai E; Jonsson C; Larsson SA; Jacobsson H; Kogner P
Review: MEDICAL ONCOLOGY. 1999;16(3):166-176
The role of busulfan in bone marrow transplantation
Hassan M
Published conference paper: EUROPEAN JOURNAL OF CANCER. 1997;33(12):2084-2089
Somatostatin in neuroblastoma and ganglioneuroma
Kogner P; Borgström P; Bjellerup P; Schilling FH; Refai E; Jonsson C; Dominici C; Wassberg E; Bihl H; Jacobsson H; Theodorsson E; Hassan M
Review: LEUKEMIA AND LYMPHOMA. 1996;22(5-6):395-407
Aspects concerning busulfan pharmacokinetics and bioavailability
Hassan M; Ehrsson H; Ljungman P
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Professor, Senior, Department of Laboratory Medicine, Karolinska Institutet, 2019-2025

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Docent, Karolinska Institutet, 1994

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