Mikael Kastengren

Mikael Kastengren

Phd Student
Visiting address: Tema Hjärta, Kärl och Neuro, Karolinska universitetssjukhuset, 17176 Stockholm
Postal address: K1 Molekylär medicin och kirurgi, K1 MMK Thoraxkirurgi, 171 76 Stockholm
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About me

  • Mikael Kastengren is a doctoral student with the Institution for Molecular
    Medicine and Surgery in the thoracic surgery research group. He is a resident
    in cardiology at Karolinska University Hospital. In his future clinical
    career he plans to go into interventional cardiology.

Research

  • Research Aims
    We aim to establish a fundament for the conduct of studies regarding
    minimally invasive heart valve surgery by linking pre-, peri-, and
    postoperative patient-level data. We will investigate differences in
    morbidity and mortality associated with minimally invasive compared with
    conventional full sternotomy aortic and mitral valve surgery.
    Sub-studies
    Five sub-studies are planned:
    1. Percutaneous plug-based arteriotomy closure device use in minimally
    invasive mitral valve surgery.
    /Comparison of conventional surgical cut-down versus a percutaneous
    plug-based arteriotomy closure device to close large bore vascular incisions
    in minimally invasive mitral valve surgery./
    2. Leaflet thickening and stent geometry in novel bioprosthetic aortic valves
    used in minimally invasive aortic valve replacement.
    /50 patients who underwent minimally invasive aortic valve replacement
    studied by cardiac computed tomography to assess the association between
    leaflet thickening and stent geometry./
    3. Minimally invasive versus conventional mitral valve surgery.
    /Comparison of 300 patients operated with full sternotomy and 300 patients
    operated with minithoracotomy before and after the introduction of a
    minimally invasive mitral valve surgery programme./
    4. Surgical trauma after minimally invasive compared with full sternotomy
    aortic valve replacement.
    /40 patients randomized 1:1 to ministernotomy or full sternotomy aortic valve
    replacement assessed for surgically-mediated trauma./
    5. A randomized study investigating mortality and morbidity after minimally
    invasive compared with full sternotomy aortic valve replacement.
    /100 patients randomized 1:1 to ministernotomy or full sternotomy aortic
    valve replacement./

Articles

All other publications

Employments

  • Phd Student, Department of Molecular Medicine and Surgery, Karolinska Institutet, 2023-2024

Degrees and Education

  • Degree Of Master Of Science In Medicine, Karolinska Institutet, 2013

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