Michele Azzolini

Publications
Public outreach and news

Articles

Article: JOURNAL OF EXPERIMENTAL AND CLINICAL CANCER RESEARCH. 2022;41(1):64
Pharmacological modulation of Kv1.3 potassium channel selectively triggers pathological B lymphocyte apoptosis in vivo in a genetic CLL model.
Severin F; Urbani A; Varanita T; Bachmann M; Azzolini M; Martini V; Pizzi M; Tos APD; Frezzato F; Mattarei A; Ghia P; Bertilaccio MTS; Gulbins E; Paradisi C; Zoratti M; Semenzato GC; Leanza L; Trentin L; Szabò I
Article: AMERICAN JOURNAL OF PHYSIOLOGY - CELL PHYSIOLOGY. 2022;322(1):C49-C62
Changes in plasma concentration of kynurenine following intake of branched-chain amino acids are not caused by alterations in muscle kynurenine metabolism
Jonsson WO; Ponette J; Horwath O; Rydenstam T; Soderlund K; Ekblom B; Azzolini M; Ruas JL; Blomstrand E
Article: CELL METABOLISM. 2021;33(11):2215-2230.e8
Muscle-secreted neurturin couples myofiber oxidative metabolism and slow motor neuron identity
Correia JC; Kelahmetoglu Y; Jannig PR; Schweingruber C; Shvaikovskaya D; Zhengye L; Cervenka I; Khan N; Stec M; Oliveira M; Nijssen J; Martinez-Redondo V; Ducommun S; Azzolini M; Lanner JT; Kleiner S; Hedlund E; Ruas JL
Article: OXIDATIVE MEDICINE AND CELLULAR LONGEVITY. 2021;2021:7658501
Multiple Mechanisms Converging on Transcription Factor EB Activation by the Natural Phenol Pterostilbene
La Spina M; Azzolini M; Salmaso A; Parrasia S; Galletta E; Schiavone M; Chrisam M; Mattarei A; Di Benedetto G; Ballabio A; Tiso N; Zoratti M; Biasutto L
Article: REDOX BIOLOGY. 2020;37:101705
Insight into the mechanism of cytotoxicity of membrane-permeant psoralenic Kv1.3 channel inhibitors by chemical dissection of a novel member of the family
Peruzzo R; Mattarei A; Azzolini M; Becker-Flegler KA; Romio M; Rigoni G; Carrer A; Biasutto L; Parrasia S; Kadow S; Manago A; Urbani A; Rossa A; Semenzato G; Soriano ME; Trentin L; Ahmad S; Edwards M; Gulbins E; Paradisi C; Zoratti M; Leanza L; Szabo I
Article: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2019;20(21):E5377-5377
Browning Effects of a Chronic Pterostilbene Supplementation in Mice Fed a High-Fat Diet
La Spina M; Galletta E; Azzolini M; Gomez Zorita S; Parrasia S; Salvalaio M; Salmaso A; Biasutto L
Article: CELLULAR PHYSIOLOGY AND BIOCHEMISTRY. 2019;52(2):232-239
Pterostilbene Improves Cognitive Performance in Aged Rats: An in Vivo Study.
La Spina M; Sansevero G; Biasutto L; Zoratti M; Peruzzo R; Berardi N; Sale A; Azzolini M
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2018;500(1):51-58
Mitochondrial potassium channels in cell death
Checchetto V; Azzolini M; Peruzzo R; Capitanio P; Leanza L
Article: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY. 2017;135:77-88
Novel lipid-mimetic prodrugs delivering active compounds to adipose tissue
Mattarei A; Rossa A; Bombardelli V; Azzolini M; La Spina M; Paradisi C; Zoratti M; Biasutto L
Article: ONCOTARGET. 2017;8(24):38276-38293
Tumor-reducing effect of the clinically used drug clofazimine in a SCID mouse model of pancreatic ductal adenocarcinoma
Zaccagnino A; Manago A; Leanza L; Gontarewitz A; Linder B; Azzolini M; Biasutto L; Zoratti M; Peruzzo R; Legler K; Trauzold A; Kalthoff H; Szabo I
Article: EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS. 2017;115:149-158
New natural amino acid-bearing prodrugs boost pterostilbene's oral pharmacokinetic and distribution profile
Azzolini M; Mattarei A; La Spina M; Fanin M; Chiodarelli G; Romio M; Zoratti M; Paradisi C; Biasutto L
Article: CANCER CELL. 2017;31(4):516-531.e10
Direct Pharmacological Targeting of a Mitochondrial Ion Channel Selectively Kills Tumor Cells In Vivo
Leanza L; Romio M; Becker KA; Azzolini M; Trentin L; Manago A; Venturini E; Zaccagnino A; Mattarei A; Carraretto L; Urbani A; Kadow S; Biasutto L; Martini V; Severin F; Peruzzo R; Trimarco V; Egberts J-H; Hauser C; Visentin A; Semenzato G; Kalthoff H; Zoratti M; Gulbins E; Paradisi C; Szabo I
Article: NEUROSIGNALS. 2017;25(1):26-38
Targeting the Potassium Channel Kv1.3 Kills Glioblastoma Cells.
Venturini E; Leanza L; Azzolini M; Kadow S; Mattarei A; Weller M; Tabatabai G; Edwards MJ; Zoratti M; Paradisi C; Szabò I; Gulbins E; Becker KA
Article: BIOCHIMICA ET BIOPHYSICA ACTA: INTERNATIONAL JOURNAL OF BIOCHEMISTRY AND BIOPHYSICS. 2016;1863(10):2515-2530
The mitochondrial permeability transition pore in AD 2016: An update
Biasutto L; Azzolini M; Szabo I; Zoratti M
Article: SCIENTIFIC REPORTS. 2015;5:15216
Amino Acid Carbamates As Prodrugs Of Resveratrol
Mattarei A; Azzolini M; La Spina M; Zoratti M; Paradisi C; Biasutto L
Article: MOLECULAR PHARMACEUTICS. 2015;12(9):3441-3454
Synthesis and Evaluation as Prodrugs of Hydrophilic Carbamate Ester Analogues of Resveratrol
Azzolini M; Mattarei A; La Spina M; Marotta E; Zoratti M; Paradisi C; Biasutto L
Article: MOLECULES. 2015;20(9):16085-16102
N-Monosubstituted Methoxy-oligo(ethylene glycol) Carbamate Ester Prodrugs of Resveratrol
Mattarei A; Azzolini M; Zoratti M; Biasutto L; Paradisi C
Article: ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY. 2014;14(10):1332-1342
Improving the Efficacy of Plant Polyphenols
Biasutto L; Mattarei A; Sassi N; Azzolini M; Romio M; Paradisi C; Zoratti M
Article: MOLECULAR NUTRITION AND FOOD RESEARCH. 2014;58(11):2122-2132
Pharmacokinetics and tissue distribution of pterostilbene in the rat
Azzolini M; La Spina M; Mattarei A; Paradisi C; Zoratti M; Biasutto L
Article: MOLECULES. 2014;19(10):15900-15917
New Water-Soluble Carbamate Ester Derivatives of Resveratrol
Mattarei A; Carraro M; Azzolini M; Paradisi C; Zoratti M; Biasutto L
Article: BIOCHIMICA ET BIOPHYSICA ACTA: INTERNATIONAL JOURNAL OF BIOCHEMISTRY AND BIOPHYSICS. 2014;1837(10):1781-1789
Cytotoxicity of mitochondria-targeted resveratrol derivatives: Interactions with respiratory chain complexes and ATP synthase
Sassi N; Mattarei A; Azzolini M; Szabo' I; Paradisi C; Zoratti M; Biasutto L
Article: CURRENT PHARMACEUTICAL DESIGN. 2014;20(2):172-179
Mitochondria-targeted Resveratrol Derivatives Act as Cytotoxic Pro-oxidants
Sassi N; Mattarei A; Azzolini M; Bernardi P; Szabo I; Paradisi C; Zoratti M; Biasutto L
Article: MOLECULAR PHARMACEUTICS. 2013;10(7):2781-2792
Acetal Derivatives as Prodrugs of Resveratrol
Mattarei A; Azzolini M; Carraro M; Sassi N; Zoratti M; Paradisi C; Biasutto L
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Corrigendum: REDOX BIOLOGY. 2021;45:102036
Insight into the mechanism of cytotoxicity of membrane-permeant psoralenic Kv1.3 channel inhibitors by chemical dissection of a novel member of the family (vol 37, 101705, 2020)
Peruzzo R; Mattarei A; Azzolini M; Becker-Flegler KA; Romio M; Rigoni G; Carrer A; Biasutto L; Parrasia S; Kadow S; Manag A; Urbani A; Rossa A; Semenzato G; Soriano ME; Trentin L; Ahmad S; Edwards M; Gulbins E; Paradisi C; Zoratti M; Leanza L; Szabo I
Review: AMERICAN JOURNAL OF PHYSIOLOGY - CELL PHYSIOLOGY. 2020;318(5):C818-C830
The kynurenine connection: how exercise shifts muscle tryptophan metabolism and affects energy homeostasis, the immune system, and the brain
Martin KS; Azzolin M; Ruas JL
Review: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY. 2019;181:111557
Strategies to target bioactive molecules to subcellular compartments. Focus on natural compounds
Biasutto L; Mattarei A; La Spina M; Azzolini M; Parrasia S; Szabo I; Zoratti M
Review: ANNALS OF THE NEW YORK ACADEMY OF SCIENCES. 2017;1403(1):27-37
Resveratrol derivatives as a pharmacological tool
Biasutto L; Mattarei A; Azzolini M; La Spina M; Sassi N; Romio M; Paradisi C; Zoratti M

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