Michael Chrobok

Publications
CV
Public outreach and news

Articles

Article: SCIENCE SIGNALING. 2023;16(780):eabq0752

SHP-1 localization to the activating immune synapse promotes NK cell tolerance in MHC class I deficiency.

Schmied L; Luu TT; Søndergaard JN; Hald SH; Meinke S; Mohammad DK; Singh SB; Mayer C; Perinetti Casoni G; Chrobok M; Schlums H; Rota G; Truong HM; Westerberg LS; Guarda G; Alici E; Wagner AK; Kadri N; Bryceson YT; Saeed MB; Höglund P
Article: CELL REPORTS MEDICINE. 2022;3(2):100508

Autologous NK cells as consolidation therapy following stem cell transplantation in multiple myeloma.

Nahi H; Chrobok M; Meinke S; Gran C; Marquardt N; Afram G; Sutlu T; Gilljam M; Stellan B; Wagner AK; Blomberg P; Holmqvist P-H; Walther-Jallow L; Mellström K; Liwing J; Gustafsson C; Månsson R; Klimkowska M; Gahrton G; Lund J; Ljungman P; Ljunggren H-G; Alici E
Article: FRONTIERS IN IMMUNOLOGY. 2022;13:896242

Process Development for Adoptive Cell Therapy in Academia: A Pipeline for Clinical-Scale Manufacturing of Multiple TCR-T Cell Products.

Silva DN; Chrobok M; Rovesti G; Healy K; Wagner AK; Maravelia P; Gatto F; Mazza M; Mazzotti L; Lohmann V; Sällberg Chen M; Sällberg M; Buggert M; Pasetto A
Article: FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY. 2021;9:612714

The Effect of Mesenchymal Stromal Cells Derived From Endometriotic Lesions on Natural Killer Cell Function.

Abomaray F; Wagner AK; Chrobok M; Ekblad-Nordberg Å; Gidlöf S; Alici E; Götherström C
Article: STEM CELL REPORTS. 2020;14(4):648-662

Generation of Retinal Pigment Epithelial Cells Derived from Human Embryonic Stem Cells Lacking Human Leukocyte Antigen Class I and II.

Petrus-Reurer S; Winblad N; Kumar P; Gorchs L; Chrobok M; Wagner AK; Bartuma H; Lardner E; Aronsson M; Plaza Reyes Á; André H; Alici E; Kaipe H; Kvanta A; Lanner F
Journal article: CANCER IMMUNOLOGY RESEARCH. 2020;8(4_Supplement):a55

Abstract A55: Natural killer cells genetically modified to overexpress DNAM-1 exert enhanced antitumor responses against CD112/CD155+ sarcomas and other malignancies

Sayitoglu EC; Chrobok M; Georgoudaki A-M; Josey BJ; Hartman M; Vallabhaneni E; Herekar R; Bergeron S; Krueger R; Sutlu T; Alici E; Temple HT; Duru AD
Journal article: CANCER IMMUNOLOGY RESEARCH. 2020;8(4_Supplement):a21

Abstract A21: Engineering antigen-specific natural killer cells against the melanoma-associated antigen tyrosinase via TCR gene transfer

Parlar A; Sayitoglu EC; Pamukcu C; Georgoudaki A-M; Ozkazanc D; Aras M; Josey B; Chrobok M; Branecki S; Zahedimaram P; Ikromzoda L; Alici E; Erman B; Sutlu T; Duru AD
Article: FRONTIERS IN IMMUNOLOGY. 2020;11:40

Boosting Natural Killer Cell-Mediated Targeting of Sarcoma Through DNAM-1 and NKG2D.

Sayitoglu EC; Georgoudaki A-M; Chrobok M; Ozkazanc D; Josey BJ; Arif M; Kusser K; Hartman M; Chinn TM; Potens R; Pamukcu C; Krueger R; Zhang C; Mardinoglu A; Alici E; Temple HT; Sutlu T; Duru AD
Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 2019;49(8):1278-1290

Engineering antigen-specific NK cell lines against the melanoma-associated antigen tyrosinase via TCR gene transfer.

Parlar A; Sayitoglu EC; Ozkazanc D; Georgoudaki A-M; Pamukcu C; Aras M; Josey BJ; Chrobok M; Branecki S; Zahedimaram P; Ikromzoda L; Alici E; Erman B; Duru AD; Sutlu T
Article: CANCERS. 2019;11(1):E69-69

Functional Assessment for Clinical Use of Serum-Free Adapted NK-92 Cells.

Chrobok M; Dahlberg CIM; Sayitoglu EC; Beljanski V; Nahi H; Gilljam M; Stellan B; Sutlu T; Duru AD; Alici E
Article: PLOS ONE. 2019;14(2):e0211927

Infectious complications and NK cell depletion following daratumumab treatment of Multiple Myeloma.

Nahi H; Chrobok M; Gran C; Lund J; Gruber A; Gahrton G; Ljungman P; Wagner AK; Alici E
Journal article: RESPIRATION. 2015;90(6):481-492

Autologous Peripheral Blood Mononuclear Cells as Treatment in Refractory Acute Respiratory Distress Syndrome.

Jungebluth P; Holzgraefe B; Lim ML; Duru AD; Lundin V; Heldring N; Wiklander OPB; Nordin JZ; Chrobok M; Roderburg C; Sjöqvist S; Anderstam B; Beltrán Rodríguez A; Haag JC; Gustafsson Y; Roddewig KG; Jones P; Wood MJA; Luedde T; Teixeira AI; Hermanson O; Winqvist O; Kalzén H; El Andaloussi S; Alici E; Macchiarini P

All other publications

Review: IMMUNO-ONCOLOGY AND TECHNOLOGY. 2022;16:100099

ATMP development and pre-GMP environment in academia: a safety net for early cell and gene therapy development and manufacturing.

Silva DN; Chrobok M; Ahlén G; Blomberg P; Sällberg M; Pasetto A
Review: CANCERS. 2021;13(17):4334

Liquid Biopsy in Hepatocellular Carcinoma: Opportunities and Challenges for Immunotherapy.

Maravelia P; Silva DN; Rovesti G; Chrobok M; Stål P; Lu Y-C; Pasetto A
Thesis / dissertation: 2019

Natural killer cells, multiple myeloma, and daratumumab : a love-hate relationship

Chrobok, Michael
Letter: BRITISH JOURNAL OF HAEMATOLOGY. 2016;174(3):473-477

Re-challenging with anti-CD38 monotherapy in triple-refractory multiple myeloma patients is a feasible and safe approach.

Alici E; Chrobok M; Lund J; Ahmadi T; Khan I; Duru AD; Nahi H
Review: FRONTIERS IN IMMUNOLOGY. 2015;6:605

Natural Killer Cell-Based Therapies Targeting Cancer: Possible Strategies to Gain and Sustain Anti-Tumor Activity.

Dahlberg CIM; Sarhan D; Chrobok M; Duru AD; Alici E

Employments

Research Specialist, Department of Molecular Medicine and Surgery, Karolinska Institutet, 2024-2024

Degrees and Education

Degree Of Doctor Of Philosophy, Department of Medicine, Huddinge, Karolinska Institutet, 2019

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