Marie-Stephanie Aschtgen

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About me

Dr. Marie-Stéphanie Aschtgen, Assistant Professor at the Department of
Microbiology, Tumor and Cell Biology (MTC) at Karolinska Institutet (Birgitta
Henriques-Normark Unit).
My research focuses on /Klebsiella pneumoniae/ pathogenicity.
www.researchgate.net/profile/Marie_Stephanie_Aschtgen
www.linkedin.com/in/marie-stephanie-aschtgen-63374154

Articles

Article: ONCOGENE. 2022;41(15):2173-2186
Enterobacteria impair host p53 tumor suppressor activity through mRNA destabilization
Aschtgen M-S; Fragkoulis K; Sanz G; Normark S; Selivanova G; Henriques-Normark B; Peuget S
Article: VIRULENCE. 2021;12(1):389-403
Neisseria meningitidis IgA1-specific serine protease exhibits novel cleavage activity against IgG3
Spoerry C; Karlsson J; Aschtgen M-S; Loh E
Article: FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY. 2021;11:808601
The Role of Minor Pilins in Assembly and Function of the Competence Pilus of Streptococcus pneumoniae
Oliveira V; Aschtgen M-S; van Erp A; Henriques-Normark B; Muschiol S
Article: BIOSENSORS AND BIOELECTRONICS. 2021;171:112732
Biofilm interfacial acidity evaluation by pH-Responsive luminescent nanoparticle films
Merkl P; Aschtgen M-S; Henriques-Normark B; Sotiriou GA
Article: EMBO MOLECULAR MEDICINE. 2020;12(11):e12695
Mannose receptor-derived peptides neutralize pore-forming toxins and reduce inflammation and development of pneumococcal disease
Subramanian K; Iovino F; Tsikourkitoudi V; Merkl P; Ahmed S; Berry SB; Aschtgen M-S; Svensson M; Bergman P; Sotiriou GA; Henriques-Normark B
Article: MBIO. 2020;11(5):e01774-e01720
Sex Steroids Induce Membrane Stress Responses and Virulence Properties in Pseudomonas aeruginosa
Vidaillac C; Yong VFL; Aschtgen M-S; Qu J; Yang S; Xu G; Seng ZJ; Brown AC; Ali MK; Jaggi TK; Sankaran J; Foo YH; Righetti F; Nedumaran AM; Mac Aogain M; Roizman D; Richard J-A; Rogers TR; Toyofuku M; Luo D; Loh E; Wohland T; Czarny B; Horvat JC; Hansbro PM; Yang L; Li L; Normark S; Normark BH; Chotirmall SH
Article: CELLULAR MICROBIOLOGY. 2020;22(4):e13177
Tracking the cargo of extracellular symbionts into host tissues with correlated electron microscopy and nanoscale secondary ion mass spectrometry imaging
Cohen SK; Aschtgen M-S; Lynch JB; Koehler S; Chen F; Escrig S; Daraspe J; Ruby EG; Meibom A; McFall-Ngai M
Article: JOURNAL OF BACTERIOLOGY. 2019;201(12):e00173-e00119
Role and Recruitment of the TagL Peptidoglycan-Binding Protein during Type VI Secretion System Biogenesis
Santin YG; Camy CE; Zoued A; Doan T; Aschtgen M-S; Cascales E
Article: MICROBIOLOGY SPECTRUM. 2019;7(1):10.1128/microbiolspec.psi
Gram-Positive Type IV Pili and Competence
Muschiol S; Aschtgen M-S; Nannapaneni P; Henriques-Normarkt B
Article: NATURE COMMUNICATIONS. 2018;9(1):3398
Factor H binding proteins protect division septa on encapsulated Streptococcus pneumoniae against complement C3b deposition and amplification
Pathak A; Bergstrand J; Sender V; Spelmink L; Aschtgen M-S; Muschiol S; Widengren J; Henriques-Normark B
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2017;292(34):14134-14146
Structure of the competence pilus major pilin ComGC in Streptococcus pneumoniae
Muschiol S; Erlendsson S; Aschtgen M-S; Oliveira V; Schmieder P; de Lichtenberg C; Teilum K; Boesen T; Akbey U; Henriques-Normark B
Article: JOURNAL OF MOLECULAR BIOLOGY. 2016;428(22):4424-4437
Molecular Dissection of the Interface between the Type VI Secretion TssM Cytoplasmic Domain and the TssG Baseplate Component
Logger L; Aschtgen M-S; Guerin M; Cascales E; Durand E
Article: JOURNAL OF BACTERIOLOGY. 2016;198(16):2156-2165
Rotation of Vibrio fischeri Flagella Produces Outer Membrane Vesicles That Induce Host Development
Aschtgen M-S; Lynch JB; Koch E; Schwartzman J; McFall-Ngai M; Ruby E
Article: CELLULAR MICROBIOLOGY. 2016;18(4):488-499
Vibrio fischeri-derived outer membrane vesicles trigger host development
Aschtgen M-S; Wetzel K; Goldman W; McFall-Ngai M; Ruby E
Article: MOLECULAR MICROBIOLOGY. 2016;99(6):1099-1118
A phospholipase A₁ antibacterial Type VI secretion effector interacts directly with the C-terminal domain of the VgrG spike protein for delivery
Flaugnatti N; Thi THL; Canaan S; Aschtgen M-S; Van SN; Blangy S; Kellenberger C; Roussel A; Cambillau C; Cascales E; Journet L
Article: NATURE. 2015;523(7562):555-560
Biogenesis and structure of a type VI secretion membrane core complex
Durand E; Van SN; Zoued A; Logger L; Pehau-Arnaudet G; Aschtgen M-S; Spinelli S; Desmyter A; Bardiaux B; Dujeancourt A; Roussel A; Cambillau C; Cascales E; Fronzes R
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2012;287(17):14157-14168
Structural Characterization and Oligomerization of the TssL Protein, a Component Shared by Bacterial Type VI and Type IVb Secretion Systems
Durand E; Zoued A; Spinelli S; Watson PJH; Aschtgen M-S; Journet L; Cambillau C; Cascales E
Article: MICROBIOLOGYOPEN. 2012;1(1):71-82
The C-tail anchored TssL subunit, an essential protein of the enteroaggregative Escherichia coli Sci-1 Type VI secretion system, is inserted by YidC
Aschtgen M-S; Zoued A; Lloubes R; Journet L; Cascales E
Article: PLOS PATHOGENS. 2011;7(11):e1002386
Towards a Structural Comprehension of Bacterial Type VI Secretion Systems: Characterization of the TssJ-TssM Complex of an Escherichia coli Pathovar
Felisberto-Rodrigues C; Durand E; Aschtgen M-S; Blangy S; Ortiz-Lombardia M; Douzi B; Cambillau C; Cascales E
Article: VIRULENCE. 2010;1(6):535-540
Anchoring the type VI secretion system to the peptidoglycan TssL, TagL, TagP, ... what else?
Aschtgen M-S; Thomas MS; Cascales E
Article: MOLECULAR MICROBIOLOGY. 2010;75(4):886-899
The SciZ protein anchors the enteroaggregative Escherichia coli Type VI secretion system to the cell wall
Aschtgen M-S; Gavioli M; Dessen A; Lloubes R; Cascales E
Article: JOURNAL OF BACTERIOLOGY. 2008;190(22):7523-7531
SciN Is an Outer Membrane Lipoprotein Required for Type VI Secretion in Enteroaggregative Escherichia coli
Aschtgen M-S; Bernard CS; De Bentzmann S; Lloubes R; Cascales E
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All other publications

Corrigendum: MBIO. 2020;11(6):e02809-e02820
Sex Steroids Induce Membrane Stress Responses and Virulence Properties in Pseudomonas aeruginosa (vol 11, e01774-20, 2020)
Vidaillac C; Yong VFL; Aschtgen M-S; Qu J; Yang S; Xu G; Seng ZJ; Brown AC; Ali MK; Jaggi TK; Sankaran J; Foo YH; Righetti F; Nedumaran AM; Mac Aogain M; Roizman D; Richard J-A; Rogers TR; Toyofuku M; Luo D; Loh E; Wohland T; Czarny B; Horvat JC; Hansbro PM; Yang L; Li L; Normark S; Henriques-Normark B; Chotirmall SH
Editorial comment: JOURNAL OF INTERNAL MEDICINE. 2020;287(3):336-338
The rise of hyper-virulence
Aschtgen M-S; Henriques-Normark B; Normark S
Review: NPJ BIOFILMS AND MICROBIOMES. 2019;5(1):32
Insights into flagellar function and mechanism from the squid-vibrio symbiosis
Aschtgen M-S; Brennan CA; Nikolakakis K; Cohen S; McFall-Ngai M; Ruby EG
Review: BIOCHIMICA ET BIOPHYSICA ACTA: INTERNATIONAL JOURNAL OF BIOCHEMISTRY AND BIOPHYSICS. 2014;1843(8):1664-1673
Architecture and assembly of the Type VI secretion system
Zoued A; Brunet YR; Durand E; Aschtgen M-S; Logger L; Douzi B; Journet L; Cambillau C; Cascales E

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