Marco Moedas

Publications
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Articles

Article: HUMAN MOLECULAR GENETICS. 2022;31(12):2049-2062
Pathogenic SLC25A26 variants impair SAH transport activity causing mitochondrial disease
Schober FA; Tang JX; Sergeant K; Moedas MF; Zierz CM; Moore D; Smith C; Lewis D; Guha N; Hopton S; Falkous G; Lam A; Pyle A; Poulton J; Gorman GS; Taylor RW; Freyer C; Wredenberg A
Article: HUMAN MUTATION. 2021;42(4):378-384
Severe congenital lactic acidosis and hypertrophic cardiomyopathy caused by an intronic variant in NDUFB7
Correia SP; Moedas MF; Naess K; Bruhn H; Maffezzini C; Calvo-Garrido J; Lesko N; Wibom R; Schober FA; Jemt A; Stranneheim H; Freyer C; Wedell A; Wredenberg A
Article: SCIENCE ADVANCES. 2021;7(8):eabf0717
The one-carbon pool controls mitochondrial energy metabolism via complex I and iron-sulfur clusters
Schober FA; Moore D; Atanassov I; Moedas MF; Clemente P; Vegvari A; El Fissi N; Filograna R; Bucher A-L; Hinze Y; The M; Hedman E; Chernogubova E; Begzati A; Wibom R; Jain M; Nilsson R; Kall L; Wedell A; Freyer C; Wredenberg A
Article: MOLECULAR & CELLULAR PROTEOMICS. 2021;20:100065
Stable Isotope Labeling of Amino Acids in Flies (SILAF) Reveals Differential Phosphorylation of Mitochondrial Proteins Upon Loss of OXPHOS Subunits
Rosenberger FA; Atanassov I; Moore D; Calvo-Garrido J; Moedas MF; Wedell A; Freyer C; Wredenberg A
Article: ANALYTICAL BIOCHEMISTRY. 2017;535:47-55
Advances in methods for characterization of hepatic urea cycle enzymatic activity in HepaRG cells using UPLC-MS/MS
Moedas MF; Adam AAA; Farelo MA; Ijlst L; Chamuleau RAFM; Hoekstra R; Wanders RJA; Silva MFB
Article: METABOLOMICS. 2016;12(8):142
Transient decrease of hepatic NAD⁺ and amino acid alterations during treatment with valproate: new insights on drug-induced effects in vivo using targeted MS-based metabolomics
Moedas MF; van Cruchten AG; IJlst L; Kulik W; de Almeida IT; Diogo L; Wanders RJA; Silva MFB
Article: BIOCHEMICAL PHARMACOLOGY. 2011;82(11):1740-1746
Valproic acid utilizes the isoleucine breakdown pathway for its complete β-oxidation
Luis PBM; Ruiter JP; Ofman R; Ijlst L; Moedas M; Diogo L; Garcia P; de Almeida IT; Duran M; Wanders RJ; Silva MFB

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Review: CELLULAR AND MOLECULAR LIFE SCIENCES. 2021;78(23):7451-7468
Dihydrolipoamide dehydrogenase, pyruvate oxidation, and acetylation-dependent mechanisms intersecting drug iatrogenesis
Duarte IF; Caio J; Moedas MF; Rodrigues LA; Leandro AP; Rivera IA; Silva MFB
Meeting abstract: FREE RADICAL BIOLOGY AND MEDICINE. 2018;120:s108
Drug-induced effects on urea cycle enzymes associate with altered ammonia metabolism, NAD⁺ biosynthesis and mitochondrial protein acetylome
Moedas MF; Farelo M; Caio J; Pereira A; Ijlst L; Wanders RJA; Silva MFB
Meeting abstract: TOXICOLOGY LETTERS. 2015;238(2):s321
NAD depletion and mitochondrial protein hyperacetylation: New insights on liver toxicity and drug-induced effects in vivo
Moedas M; Van Chruchten A; Ijlst L; Castro R; Houtkooper RH; Wanders RJA; Silva MFB

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