Marcel Tarbier

About me
Publications
Public outreach and news

Research

Non-genetic single-cell heterogeneity
We are exploring mechanisms by which individual cells of otherwise
homogeneous populations achieve molecular heterogeneity and how this
heterogeneity affects their molecular behaviour i.e. to better understand why
certain cancer cells develop to become persister cells that are resistant to
treatment. For this we develop and apply novel single-cell approaches and
integrate data from various omics technologies.

Articles

Journal article: NAR GENOMICS AND BIOINFORMATICS. 2024;6(2):lqae045
Malat1 affects transcription and splicing through distinct pathways in mouse embryonic stem cells
Aslanzadeh M; Stanicek L; Tarbier M; Marmol-Sanchez E; Biryukova I; Friedlander MR
Article: NATURE COMMUNICATIONS. 2024;15(1):2744
Gene-expression memory-based prediction of cell lineages from scRNA-seq datasets
Eisele AS; Tarbier M; Dormann AA; Pelechano V; Suter DM
Article: MOLECULAR GENETICS AND GENOMICS. 2022;297(2):463-484
The SWI/SNF subunit BRG1 affects alternative splicing by changing RNA binding factor interactions with nascent RNA.
Gañez-Zapater A; Mackowiak SD; Guo Y; Tarbier M; Jordán-Pla A; Friedländer MR; Visa N; Östlund Farrants A-K
Article: NUCLEIC ACIDS RESEARCH (NAR). 2022;50(D1):D204-D210
MirGeneDB 2.1: toward a complete sampling of all major animal phyla
Fromm B; Hoye E; Domanska D; Zhong X; Aparicio-Puerta E; Ovchinnikov V; Umu SU; Chabot PJ; Kang W; Aslanzadeh M; Tarbier M; Marmol-Sanchez E; Urgese G; Johansen M; Hovig E; Hackenberg M; Friedlander MR; Peterson KJ
Article: COMMUNICATIONS BIOLOGY. 2021;4(1):624
A combined approach for single-cell mRNA and intracellular protein expression analysis.
Reimegård J; Tarbier M; Danielsson M; Schuster J; Baskaran S; Panagiotou S; Dahl N; Friedländer MR; Gallant CJ
Article: RNA: A PUBLICATION OF THE RNA SOCIETY. 2020;27(3):rna.078410.120-334
Ancient microRNA profiles of a 14,300-year-old canid samples confirm taxonomic origin and give glimpses into tissue-specific gene regulation from the Pleistocene.
Fromm B; Tarbier M; Smith O; Marmol-Sanchez E; Dalen L; Gilbert TP; Friedlander MR
Article: CELL REPORTS. 2020;33(10):108448
Circulating miRNA Spaceflight Signature Reveals Targets for Countermeasure Development.
Malkani S; Chin CR; Cekanaviciute E; Mortreux M; Okinula H; Tarbier M; Schreurs A-S; Shirazi-Fard Y; Tahimic CGT; Rodriguez DN; Sexton BS; Butler D; Verma A; Bezdan D; Durmaz C; MacKay M; Melnick A; Meydan C; Li S; Garrett-Bakelman F; Fromm B; Afshinnekoo E; Langhorst BW; Dimalanta ET; Cheng-Campbell M; Blaber E; Schisler JC; Vanderburg C; Friedländer MR; McDonald JT; Costes SV; Rutkove S; Grabham P; Mason CE; Beheshti A
Article: NATURE COMMUNICATIONS. 2020;11(1):5445
Nuclear gene proximity and protein interactions shape transcript covariations in mammalian single cells
Tarbier M; Mackowiak SD; Frade J; Catuara-Solarz S; Biryukova I; Gelali E; Menendez DB; Zapata L; Ossowski S; Bienko M; Gallant CJ; Friedlander MR
Article: NUCLEIC ACIDS RESEARCH (NAR). 2018;46(22):11869-11882
Next-generation sequencing reveals two populations of damage-induced small RNAs at endogenous DNA double-strand breaks
Bonath F; Domingo-Prim J; Tarbier M; Friedlander MR; Visa N
Article: MOLECULAR METABOLISM. 2018;18:15-24
Control of hepatic gluconeogenesis by Argonaute2
Yan X; Wang Z; Bishop CA; Weitkunat K; Feng X; Tarbier M; Luo J; Friedlander MR; Burkhardt R; Klaus S; Willnow TE; Poy MN
Article: MOLECULAR METABOLISM. 2018;17:49-60
microRNA-205-5p is a modulator of insulin sensitivity that inhibits FOXO function
Langlet F; Tarbier M; Haeusler RA; Camastra S; Ferrannini E; Friedlander MR; Accili D
Article: JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM (JCEM). 2017;102(10):3749-3755
Differential Impact of Glucose Administered Intravenously and Orally on Circulating miR-375 Levels in Human Subjects
Yan X; Wang Z; Westberg-Rasmussen S; Tarbier M; Rathjen T; Tattikota SG; Peck BCE; Kanke M; Oxvig C; Frystyk J; Starup-Linde J; Sethupathy P; Friedlander MR; Gregersen S; Poy MN

All other publications

Preprint: BIORXIV. 2024
Landscape of microRNA and target expression variation and covariation in single mouse embryonic stem cells
Tarbier M; Mackowiak SD; Sekar V; Bonath F; Yapar E; Fromm B; Faridani OR; Biryukova I; Friedländer MR
Editorial comment: RNA: A PUBLICATION OF THE RNA SOCIETY. 2022;28(6):781-785
The limits of human microRNA annotation have been met
Fromm B; Zhong X; Tarbier M; Friedlander MR; Hackenberg M

Research

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