Manuela Gustafsson Sfetcovici

About me
Publications
CV
Public outreach and news

Research

Research area/interest: Cellular signalling of Btk: identification and
characterization of new protein binding partners.

Articles

Article: JOURNAL OF EXTRACELLULAR VESICLES. 2022;11(6):e12238

Identification of storage conditions stabilizing extracellular vesicles preparations

Gorgens A; Corso G; Hagey DW; Wiklander RJ; Gustafsson MO; Felldin U; Lee Y; Bostancioglu RB; Sork H; Liang X; Zheng W; Mohammad DK; van DWSI; Vader P; Zickler AM; Mamand DR; Ma L; Holme MN; Stevens MM; Wiklander OPB; El Andaloussi S
Article: NATURE BIOMEDICAL ENGINEERING. 2021;5(9):1084-1098

Amelioration of systemic inflammation via the display of two different decoy protein receptors on extracellular vesicles

Gupta D; Wiklander OPB; Goergens A; Conceicao M; Corso G; Liang X; Seow Y; Balusu S; Feldin U; Bostancioglu B; Jawad R; Mamand DR; Lee YXF; Hean J; Mager I; Roberts TC; Gustafsson M; Mohammad DK; Sork H; Backlund A; Lundin P; de Fougerolles A; Smith CIE; Wood MJA; Vandenbroucke RE; Nordin JZ; El-Andaloussi S
Article: JOURNAL OF EXTRACELLULAR VESICLES. 2020;9(1):1808281

Salivary extracellular vesicles inhibit Zika virus but not SARS-CoV-2 infection

Conzelmann C; Gross R; Zou M; Krueger F; Goergens A; Gustafsson MO; El Andaloussi S; Muench J; Mueller JA
Article: JOURNAL OF EXTRACELLULAR VESICLES. 2020;9(1):1800222

Quantification of extracellular vesicles in vitro and in vivo using sensitive bioluminescence imaging

Gupta D; Liang X; Pavlova S; Wiklander OPB; Corso G; Zhao Y; Saher O; Bost J; Zickler AM; Piffko A; Maire CL; Ricklefs FL; Gustafsson O; Llorente VC; Gustafsson MO; Bostancioglu RB; Mamand DR; Hagey DW; Goergens A; Nordin JZ; EL Andaloussi S
Article: FRONTIERS IN IMMUNOLOGY. 2018;9:1326

Systematic Methodological Evaluation of a Multiplex Bead-Based Flow Cytometry Assay for Detection of Extracellular Vesicle Surface Signatures

Wiklander OPB; Bostancioglu RB; Welsh JA; Zickler AM; Murke F; Corso G; Felldin U; Hagey DW; Evertsson B; Liang X-M; Gustafsson MO; Mohammad DK; Wiek C; Hanenberg H; Bremer M; Gupta D; Bjornstedt M; Giebel B; Nordin JZ; Jones JC; EL Andaloussi S; Goergens A
Article: PLOS ONE. 2017;12(4):e0174909

ANKRD54 preferentially selects Bruton's Tyrosine Kinase (BTK) from a Human Src-Homology 3 (SH3) domain library

Gustafsson MO; Mohammad' DK; Ylosmaki E; Choi H; Shrestha S; Wang Q; Nore BF; Saksela K; Smith CIE
Article: INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY. 2016;78:63-74

Protein kinase B (AKT) regulates SYK activity and shuttling through 14-3-3 and importin

Mohammad DK; Nore BF; Gustafsson MO; Mohamed AJ; Smith CIE
Article: JOURNAL OF CLINICAL INVESTIGATION. 2014;124(9):4067-4081

Splice-correcting oligonucleotides restore BTK function in X-linked agammaglobulinemia model

Bestas B; Moreno PMD; Blomberg KEM; Mohammad DK; Saleh AF; Sutlu T; Nordin JZ; Guterstam P; Gustafsson MO; Kharazi S; Piatosa B; Roberts TC; Behlke MA; Wood MJA; Gait MJ; Lundin KE; El Andaloussi S; Mansson R; Berglof A; Wengel J; Smith CIE
Article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2014;133(5):1410-1419.13

Hypomorphic homozygous mutations in phosphoglucomutase 3 (PGM3) impair immunity and increase serum IgE levels

Sassi A; Lazaroski S; Wu G; Haslam SM; Fliegauf M; Mellouli F; Patiroglu T; Unal E; Ozdemir MA; Jouhadi Z; Khadir K; Ben-Khemis L; Ben-Ali M; Ben-Mustapha I; Borchani LH; Pfeifer D; Jakob T; Khemiri M; Asplund AC; Gustafsson MO; Lundin KE; Falk-Soerqvist E; Moens LN; Gungor HE; Engelhardt KR; Dziadzio M; Stauss H; Fleckenstein B; Meier R; Prayitno K; Maul-Pavicic A; Schaffer S; Rakhmanov M; Henneke P; Kraus H; Eibel H; Koelsch U; Nadifi S; Nilsson M; Bejaoui M; Schaeffer AA; Smith CIE; Dell A; Barbouche M-R; Grimbacher B
Article: MOLECULAR AND CELLULAR BIOLOGY. 2013;33(16):3214-3226

Dual Phosphorylation of Btk by Akt/Protein Kinase B Provides Docking for 14-3-3ζ, Regulates Shuttling, and Attenuates both Tonic and Induced Signaling in B Cells

Mohammad DK; Nore BF; Hussain A; Gustafsson MO; Mohamed AJ; Smith CIE
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2013;288(10):7338-7350

Signaling of the ITK (Interleukin 2-inducible T Cell Kinase)-SYK (Spleen Tyrosine Kinase) Fusion Kinase Is Dependent on Adapter SLP-76 and on the Adapter Function of the Kinases SYK and ZAP70

Hussain A; Mohammad DK; Gustafsson MO; Uslu M; Hamasy A; Nore BF; Mohamed AJ; Smith CIE
Article: MOLECULAR AND CELLULAR BIOLOGY. 2012;32(13):2440-2453

Regulation of Nucleocytoplasmic Shuttling of Bruton's Tyrosine Kinase (Btk) through a Novel SH3-Dependent Interaction with Ankyrin Repeat Domain 54 (ANKRD54)

Gustafsson MO; Hussain A; Mohammad DK; Mohamed AJ; Vivian N; Metalnikov P; Colwill K; Pawson T; Smith CIE; Nore BF

All other publications

Thesis / dissertation: 2016

Characterization of ankyrin repeat domain 54 (ANKRD54) and its role on the regulation and subcellular localization of Bruton’s tyrosine kinase (BTK)

Gustafsson Sfetcovici, Manuela O

Employments

Laboratory Coordinator, Department of Laboratory Medicine, Karolinska Institutet, 2019-

Degrees and Education

Degree Of Doctor Of Philosophy, Department of Laboratory Medicine, Karolinska Institutet, 2016

Research

Articles

All other publications

Employments

Degrees and Education

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