Mansoureh Shahsavani

Publications
CV
Public outreach and news

Articles

Article: FRONTIERS IN GENETICS. 2021;12:803683
Partial Monosomy 21 Mirrors Gene Expression of Trisomy 21 in a Patient-Derived Neuroepithelial Stem Cell Model
Schuy J; Eisfeldt J; Pettersson M; Shahrokhshahi N; Moslem M; Nilsson D; Dahl N; Shahsavani M; Falk A; Lindstrand A
Article: CLINICAL EPIGENETICS. 2020;12(1):9
DNA methylation changes in Down syndrome derived neural iPSCs uncover co-dysregulation of ZNF and HOX3 families of transcription factors
Laan L; Klar J; Sobol M; Hoeber J; Shahsavani M; Kele M; Fatima A; Zakaria M; Anneren G; Falk A; Schuster J; Dahl N
Article: MOLECULAR NEUROBIOLOGY. 2019;56(10):7113-7127
Transcriptome and Proteome Profiling of Neural Induced Pluripotent Stem Cells from Individuals with Down Syndrome Disclose Dynamic Dysregulations of Key Pathways and Cellular Functions
Sobol M; Klar J; Laan L; Shahsavani M; Schuster J; Anneren G; Konzer A; Mi J; Bergquist J; Nordlund J; Hoeber J; Huss M; Falk A; Dahl N
Article: FRONTIERS IN GENETICS. 2019;10:896
Ataxia in Patients With Bi-Allelic NFASC Mutations and Absence of Full-Length NF186
Kvarnung M; Shahsavani M; Taylan F; Moslem M; Breeuwsma N; Laan L; Schuster J; Jin Z; Nilsson D; Lieden A; Anderlid B-M; Nordenskjold M; Lundberg ES; Birnir B; Dahl N; Nordgren A; Lindstrand A; Falk A
Article: MOLECULAR PSYCHIATRY. 2018;23(7):1674-1684
An in vitro model of lissencephaly: expanding the role of DCX during neurogenesis
Shahsavani M; Pronk RJ; Falk R; Lam M; Moslem M; Linker SB; Salma J; Day K; Schuster J; Anderlid B-M; Dahl N; Gage FH; Falk A
Article: CELL REPORTS. 2017;18(1):1-11
TRIM28 Controls a Gene Regulatory Network Based on Endogenous Retroviruses in Human Neural Progenitor Cells
Brattas PL; Jonsson ME; Fasching L; Wahlestedt JN; Shahsavani M; Falk R; Falk A; Jern P; Parmar M; Jakobsson J
Article: BIOMATERIALS. 2014;35(30):8496-8502
Spider silk for xeno-free long-term self-renewal and differentiation of human pluripotent stem cells
Wu S; Johansson J; Damdimopoulou P; Shahsavani M; Falk A; Hovatta O; Rising A
Article: BIOMATERIALS. 2014;35(5):1420-1428
A 3D Alzheimer's disease culture model and the induction of P21-activated kinase mediated sensing in iPSC derived neurons
Zhang D; Pekkanen-Mattila M; Shahsavani MO; Falk A; Teixeira AI; Herland A
Journal article: ARCHIVES OF IRANIAN MEDICINE. 2011;14(4):244-249
In vitro differentiation of human bone marrow mesenchymal stem cells into hepatocyte-like cells.
Pournasr B; Mohamadnejad M; Bagheri M; Aghdami N; Shahsavani M; Malekzadeh R; Baharvand H
Journal article: STEM CELL REVIEWS AND REPORTS. 2011;7(1):103-118
Differentiation of bone marrow-derived mesenchymal stem cells into hepatocyte-like cells on nanofibers and their transplantation into a carbon tetrachloride-induced liver fibrosis model.
Piryaei A; Valojerdi MR; Shahsavani M; Baharvand H
Journal article: CYTOTHERAPY. 2010;12(4):566-568
Transplantation of allogeneic bone marrow mesenchymal stromal cell-derived hepatocyte-like cells in homozygous familial hypercholesterolemia.
Mohamadnejad M; Pournasr B; Bagheri M; Aghdami N; Shahsavani M; Hosseini LA; Taghiabadi E; Azizi H; Heidari I; Akhlaghpoor S; Calandra S; Malekzadeh R; Baharvand H
Journal article: CELL BIOLOGY INTERNATIONAL. 2010;34(6):601-605
Mesenchymal stem cell infusion therapy in a carbon tetrachloride-induced liver fibrosis model affects matrix metalloproteinase expression.
Rabani V; Shahsavani M; Gharavi M; Piryaei A; Azhdari Z; Baharvand H
Journal article: DIFFERENTIATION. 2008;76(5):465-477
Differentiation of human embryonic stem cells into functional hepatocyte-like cells in a serum-free adherent culture condition.
Baharvand H; Hashemi SM; Shahsavani M

All other publications

Conference publication: EUROPEAN JOURNAL OF HUMAN GENETICS. 2020;28(SUPPL 1):588
A case of ring chromosome 21 with hemifacial microsomia, developmental and speech delay analysed with WGS and patient-derived iPS
Schuy J; Eisfeldt J; Pettersson M; Shahrokhshahi N; Shahsavani M; Nilsson D; Falk A; Lindstrand A
Conference publication: EUROPEAN JOURNAL OF HUMAN GENETICS. 2019;27:1143
Absence of NFASC isoform NF186 causes an autosomal recessive ataxia syndrome
Kvarnung M; Shahsavani M; Taylan F; Breeuwsma N; Laan L; Schuster J; Jin Z; Nilsson D; Lieden A; Anderlid B; Nordenskjold M; Lundberg ES; Birnir B; Dahl N; Nordgren A; Lindstrand A; Falk A
Thesis / dissertation: 2018
Cellular models of human brain disorders from skin to brain
Shahsavani, Mansoureh
Conference publication: EUROPEAN JOURNAL OF HUMAN GENETICS. 2018;26:366
Modeling early neuropathology in Down syndrome and APP-associated Alzheimer's disease using Induced Pluripotent Stem Cells
Klar J; Schuster J; Laan L; Sobol M; Lorenzo LP; Nordlund J; Shahsavani M; Falk A; Dahl N

Employments

Affiliated to Research, Department of Molecular Medicine and Surgery, Karolinska Institutet, 2023-2026

Degrees and Education

Degree Of Doctor Of Philosophy, Department of neuroscience, Karolinska Institutet, 2018

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