Lucas Arruda

Publications
Public outreach and news

Articles

Article: HAEMATOLOGICA. 2022;107(8):1786-1795
A novel CD34-specific T-cell engager efficiently depletes acute myeloid leukemia and leukemic stem cells in vitro and in vivo
Arruda LCM; Stikvoort A; Lambert M; Jin L; Rivera LS; Alves RMP; de Moura TR; Mim C; Lehmann S; Axelsson-Robertson R; Dick JE; Mattsson J; Onfelt B; Carlsten M; Uhlin M
Article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2022;95(5):e13151
SARS-CoV-2 (COVID-19)-specific T cell and B cell responses in convalescent rheumatoid arthritis: Monozygotic twins pair case observation
Arruda LCM; Gaballa A; Rodrigues RDS; Makower B; Uhlin M
Article: CLINICAL & TRANSLATIONAL IMMUNOLOGY. 2022;11(4):e1389
Allogeneic haematopoietic stem cell transplantation resets T- and B-cell compartments in sickle cell disease patients.
Jarduli-Maciel LR; de Azevedo JTC; Clave E; Costa TCDM; Arruda LCM; Fournier I; Palma PVB; Lima KC; Elias JB; Stracieri ABP; Pieroni F; Cunha R; Darrigo-Júnior LG; Grecco CES; Covas DT; Silva-Pinto AC; De Santis GC; Simões BP; Oliveira MC; Toubert A; Malmegrim KCR
Article: RHEUMATOLOGY. 2021;60(12):5538-5548
Autologous haematopoietic stem cell transplantation restores the suppressive capacity of regulatory B cells in systemic sclerosis patients
Lima-Junior JR; Arruda LCM; Goncalves MS; Dias JBE; Moraes DA; Covas DT; Simoes BP; Oliveira MC; Malmegrim KCR
Article: SCIENCE TRANSLATIONAL MEDICINE. 2021;13(577):eabb0192
Characterization of ascites- and tumor-infiltrating γδ T cells reveals distinct repertoires and a beneficial role in ovarian cancer
Foord E; Arruda LCM; Gaballa A; Klynning C; Uhlin M
Article: STEM CELLS INTERNATIONAL. 2019;2019:6348060-13
CD8⁺γδ T Cells Are More Frequent in CMV Seropositive Bone Marrow Grafts and Display Phenotype of an Adaptive Immune Response
Gaballa A; Arruda LCM; Radestad E; Uhlin M
Article: JOURNAL OF IMMUNOLOGY. 2019;202(6):1859-1870
Graft γδ TCR Sequencing Identifies Public Clonotypes Associated with Hematopoietic Stem Cell Transplantation Efficacy in Acute Myeloid Leukemia Patients and Unravels Cytomegalovirus Impact on Repertoire Distribution
Arruda LCM; Gaballa A; Uhlin M
Article: BONE MARROW TRANSPLANTATION. 2018;53(10):1319-1327
Homeostatic proliferation leads to telomere attrition and increased PD-1 expression after autologous hematopoietic SCT for systemic sclerosis
Arruda LCM; Lima-Junior JR; Clave E; Moraes DA; Douay C; Fournier I; Moins-Teisserenc H; Covas DT; Simoes BP; Farge D; Toubert A; Malmegrim KCR; Oliveira MC
Article: BLOOD ADVANCES. 2018;2(2):126-141
Immune rebound associates with a favorable clinical response to autologous HSCT in systemic sclerosis patients
Arruda LCM; Malmegrim KCR; Lima-Junior JR; Clave E; Dias JBE; Moraes DA; Douay C; Fournier I; Moins-Teisserenc H; Alberdi AJ; Covas DT; Simoes BP; Lansiaux P; Toubert A; Oliveira MC
Journal article: 2018
Estudo dos mecanismos imunológicos do transplante autólogo de células-tronco hematopoéticas em pacientes com esclerose sistêmica
Arruda LCM
Article: FRONTIERS IN IMMUNOLOGY. 2018;9:2602
Autologous Hematopoietic Stem Cell Transplantation for Autoimmune Diseases: From Mechanistic Insights to Biomarkers
Ribeiro Malmegrim KC; Lima-Junior JR; Marliere Arruda LC; Cottas de Azevedo JT; Vilela de Oliveira GL; Oliveira MC
Article: JOURNAL OF HEMATOLOGY AND ONCOLOGY. 2017;10(1):21
Long-term immune reconstitution and T cell repertoire analysis after autologous hematopoietic stem cell transplantation in systemic sclerosis patients
Farge D; Arruda LCM; Brigant F; Clave E; Douay C; Marjanovic Z; Deligny C; Maki G; Gluckman E; Toubert A; Moins-Teisserenc H
Article: FRONTIERS IN IMMUNOLOGY. 2017;8:167
Immunological Balance Is Associated with Clinical Outcome after Autologous Hematopoietic Stem Cell Transplantation in Type 1 Diabetes
Malmegrim KCR; de Azevedo JTC; Arruda LCM; Abreu JRF; Couri CEB; de Oliveira GLV; Palma PVB; Scortegagna GT; Stracieri ABPL; Moraes DA; Dias JBE; Pieroni F; Cunha R; Guilherme L; Santos NM; Foss MC; Covas DT; Burt RK; Simoes BP; Voltarelli JC; Roep BO; Oliveira MC
Journal article: BLOOD. 2016;128(22):4625
Newly-Generated Regulatory B- and T-Cells Are Associated with Clinical Improvement and Reversal of Dermal Fibrosis in Systemic Sclerosis Patients after Autologous Hematopoietic Stem Cell Transplantation
Arruda LCM; Lima-Júnior JR; Clave E; Moraes DA; Douay C; Fournier I; Moins-Teisserenc H; Covas DT; Malmegrim K; Farge D; Ramalho L; Toubert A; Oliveira MC
Article: CLINICAL IMMUNOLOGY. 2016;169:47-57
Immunological correlates of favorable long-term clinical outcome in multiple sclerosis patients after autologous hematopoietic stem cell transplantation
Arruda LCM; de Azevedo JTC; de Oliveira GLV; Scortegagna GT; Rodrigues ES; Palma PVB; Brum DG; Guerreiro CT; Marques VD; Barreira AA; Covas DT; Simoes BP; Voltarelli JC; Oliveira MC; Malmegrim KCR
Article: BRAZILIAN JOURNAL OF MEDICAL AND BIOLOGICAL RESEARCH. 2016;49(4):e5062
Cytokine profile and lymphocyte subsets in type 2 diabetes
Francisco CO; Catai AM; Moura-Tonello SCG; Arruda LCM; Lopes SLB; Benze BG; Del Vale AM; Malmegrim KCR; Leal AMO
Article: ARTHRITIS RESEARCH & THERAPY. 2015;17(1):196
Transforming growth factor-β increases interleukin-13 synthesis via GATA-3 transcription factor in T-lymphocytes from patients with systemic sclerosis
Baraut J; Farge D; Jean-Louis F; Masse I; Grigore EI; Arruda LCM; Lamartine J; Verrecchia F; Michel L
Journal article: ANNALS OF THE RHEUMATIC DISEASES. 2015;74(Suppl 2):67-68
OP0010 Autologous Hematopoietic Stem Cell Transplantation Increases T-Cell PD-1 Expression and Regulatory Mechanisms in Systemic Sclerosis Patients
Arruda LCM; Oliveira MC; Moraes DA; Covas DT; Malmegrim KCR
Article: BONE MARROW TRANSPLANTATION. 2015;50(3):380-389
Autologous hematopoietic SCT normalizes miR-16,-155 and-142-3p expression in multiple sclerosis patients
Arruda LCM; Lorenzi JCC; Sousa APA; Zanette DL; Palma PVB; Panepucci RA; Brum DS; Barreira AA; Covas DT; Simoes BP; Silva WAJ; Oliveira MC; Malmegrim KCR
Journal article: ANNALS OF THE RHEUMATIC DISEASES. 2014;73(Suppl 2):356
THU0501 Hematopoietic Stem Cell Transplantation Increases Naive and Regulatory B Cells While Decreasing Memory B Cells in Systemic Sclerosis Patients
Arruda LCM; Oliveira MC; Moraes DA; Covas DT; Voltarelli JC; Malmegrim KCR
Journal article: 2013
Reconstituição imunológica após transplante autólogo de células-tronco hematopoéticas em pacientes com diabetes mellitus tipo 1 e esclerose múltipla
Arruda LCM
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All other publications

Review: CRITICAL REVIEWS IN ONCOLOGY/HEMATOLOGY. 2023;186:103988
Clinical and molecular overview of immunotherapeutic approaches for malignant skin melanoma: Past, present and future
Venzel R; Campos MCP; de Oliveira LP; Lins RVD; Siena ADD; Mesquita KT; Santos TPMD; Nohata N; Arruda LCM; Sales-Campos H; Neto MPC
Conference publication: BONE MARROW TRANSPLANTATION. 2023;58(SUPP1):355
GAMMA DELTA T CELLS RECONSTITUTION IN LONG-TERM SURVIVORS AFTER ALLOGENEIC HEMATOPOIETIC STEM CELL TRANSPLANTATION
Alagrafi F; Stikvoort A; Gaballa A; Arruda L; Poiret T; Uhlin M
Review: FRONTIERS IN IMMUNOLOGY. 2022;13:971709
Gamma delta T-cell reconstitution after allogeneic HCT: A platform for cell therapy
Gaballa A; Arruda LCM; Uhlin M
Meeting abstract: BLOOD. 2021;138:2861
A Novel CD34-Specific T-Cell Engager Efficiently Depletes Stem Cells and Acute Myeloid Leukemia Cells in Vitro and In Vivo
Arruda LCM; Jin L; Lambert M; Rivera LS; Alvez R; de Moura TR; Mim C; Axelsson-Robertson R; Dick JE; Mattsson J; Onfelt B; Carlsten M; Uhlin M
Editorial comment: TRANSPLANTATION AND CELLULAR THERAPY. 2021;27(10):803-804
The Beneficial Role of Enhanced γδT-Cells Reconstitution after Allo-SCT in MRD plus AML
Arruda LCM
Review: SEMINARS IN IMMUNOPATHOLOGY. 2021;43(1):101-117
The role of the thymus in allogeneic bone marrow transplantation and the recovery of the peripheral T-cell compartment
Velardi E; Clave E; Arruda LCM; Benini F; Locatelli F; Toubert A
Letter: RHEUMATOLOGY. 2020;59(9):e38-e40
CMV-specific clones may lead to reduced TCR diversity and relapse in systemic sclerosis patients treated with AHSCT
Arruda LCM; Clave E; Douay C; Lima-Junior JR; Slavov SN; Malmegrim KCR; Alberdi AJ; Oliveira MC; Toubert A
Review: FRONTIERS IN IMMUNOLOGY. 2020;11:1341
Evaluating Thymic Function After Human Hematopoietic Stem Cell Transplantation in the Personalized Medicine Era
Gaballa A; Clave E; Uhlin M; Toubert A; Arruda LCM
Review: BLOOD ADVANCES. 2019;3(21):3436-3448
Impact of γδ T cells on clinical outcome of hematopoietic stem cell transplantation: systematic review and meta-analysis
Arruda LCM; Gaballa A; Uhlin M
Conference publication: ANNALS OF THE RHEUMATIC DISEASES. 2019;78:1065-1066
DIFFERENTIAL RECONSTITUTION OF B-CELL SUBSETS IN SYSTEMIC SCLEROSIS PATIENTS AFTER AUTOLOGOUS HEMATOPOIETIC STEM CELL TRANSPLANTATION
Lima Junior JR; Arruda LCM; Goncalves MS; Azevedo JTC; Moraes DA; Covas DT; Oliveira MC; Malmegrim KCR
Book chapter: THYMUS TRANSCRIPTOME AND CELL BIOLOGY. 2019;p. 295-309
Thymus Rejuvenation After Autologous Hematopoietic Stem Cell Transplantation in Patients with Autoimmune Diseases
Lima-Júnior JR; Arruda LCM; de Oliveira MC; Malmegrim KCR
Conference publication: BONE MARROW TRANSPLANTATION. 2019;54:134-135
Graft γδ T-cell receptor sequencing identifies public clonotypes associated to HSCT efficacy in AML patients and unravels CMV impact on repertoire distribution
Arruda LCM; Gaballa A; Uhlin M
Book chapter: HEMATOPOIETIC CELL TRANSPLANTS. 2017;p. 535-551
Autologous Hematopoietic Cell Transplants for Autoimmune Diseases: Specific Diseases and Controversies
Arruda LCM; Oliveira MC; Malmegrim KCR; Gluckman E; Farge D
Letter: BONE MARROW TRANSPLANTATION. 2016;51(8):1146-1149
Evolution of serum cytokine profile after hematopoietic stem cell transplantation in systemic sclerosis patients
Michel L; Farge D; Baraut J; Marjanovic Z; Jean-Louis F; Porcher R; Grigore EI; Deligny C; Romijn F; Arruda LCM; van Pelt J; Levarht N; Verrecchia F; van Laar JM
Review: CURRENT RESEARCH IN TRANSLATIONAL MEDICINE. 2016;64(2):107-113
Resetting the immune response after autologous hematopoietic stem cell transplantation for autoimmune diseases
Arruda LCM; Clave E; Moins-Teisserenc H; Douay C; Farge D; Toubert A

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