Leslie Kirby

Publications
Public outreach and news

Articles

Journal article: TRENDS IN IMMUNOLOGY. 2024;45(10):750-759
Disease-associated oligodendroglia: a putative nexus in neurodegeneration.
Castelo-Branco G; Kukanja P; Guerreiro-Cacais AO; Rubio Rodríguez-Kirby LA
Article: CELL. 2024;187(8):1990-2009.e19
Cellular architecture of evolving neuroinflammatory lesions and multiple sclerosis pathology
Kukanja P; Langseth CM; Rodriguez-Kirby LAR; Agirre E; Zheng C; Raman A; Yokota C; Avenel C; Tiklova K; Guerreiro-Cacais AO; Olsson T; Hilscher MM; Nilsson M; Castelo-Branco G
Article: NEURON. 2022;110(7):1193-1210.e13
Epigenomic priming of immune genes implicates oligodendroglia in multiple sclerosis susceptibility
Meijer M; Agirre E; Kabbe M; van Tuijn CA; Heskol A; Zheng C; Falcao AM; Bartosovic M; Kirby L; Calini D; Johnson MR; Corces MR; Montine TJ; Chen X; Chang HY; Malhotra D; Castelo-Branco G
Journal article: NATURE COMMUNICATIONS. 2019;10(1):3887
Oligodendrocyte precursor cells present antigen and are cytotoxic targets in inflammatory demyelination.
Kirby L; Jin J; Cardona JG; Smith MD; Martin KA; Wang J; Strasburger H; Herbst L; Alexis M; Karnell J; Davidson T; Dutta R; Goverman J; Bergles D; Calabresi PA
Journal article: PLOS ONE. 2019;14(9):e0221747
Quetiapine has an additive effect to triiodothyronine in inducing differentiation of oligodendrocyte precursor cells through induction of cholesterol biosynthesis.
Gonzalez Cardona J; Smith MD; Wang J; Kirby L; Schott JT; Davidson T; Karnell JL; Whartenby KA; Calabresi PA
Journal article: JOURNAL OF VISUALIZED EXPERIMENTS. 2016;(108):53764
Preparation of Rat Oligodendrocyte Progenitor Cultures and Quantification of Oligodendrogenesis Using Dual-infrared Fluorescence Scanning.
Schott JT; Kirby LA; Calabresi PA; Baxi EG
Journal article: JOURNAL OF NEUROSCIENCE. 2015;35(22):8626-8639
Transfer of myelin-reactive th17 cells impairs endogenous remyelination in the central nervous system of cuprizone-fed mice.
Baxi EG; DeBruin J; Tosi DM; Grishkan IV; Smith MD; Kirby LA; Strasburger HJ; Fairchild AN; Calabresi PA; Gocke AR
Journal article: PLOS ONE. 2015;10(9):e0139008
Disparate Effects of Mesenchymal Stem Cells in Experimental Autoimmune Encephalomyelitis and Cuprizone-Induced Demyelination.
Glenn JD; Smith MD; Kirby LA; Baxi EG; Whartenby KA
Journal article: GLIA. 2014;62(9):1513-1529
A selective thyroid hormone β receptor agonist enhances human and rodent oligodendrocyte differentiation.
Baxi EG; Schott JT; Fairchild AN; Kirby LA; Karani R; Uapinyoying P; Pardo-Villamizar C; Rothstein JR; Bergles DE; Calabresi PA
Journal article: STEM CELL RESEARCH. 2012;9(3):208-217
IFN-γ-induced apoptosis of human embryonic stem cell derived oligodendrocyte progenitor cells is restricted by CXCR2 signaling.
Tirotta E; Kirby LA; Hatch MN; Lane TE
Journal article: PLOS ONE. 2012;7(6):e39329
Glycogen synthase kinase 3 (GSK3) inhibitor, SB-216763, promotes pluripotency in mouse embryonic stem cells.
Kirby LA; Schott JT; Noble BL; Mendez DC; Caseley PS; Peterson SC; Routledge TJ; Patel NV

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Conference publication: MULTIPLE SCLEROSIS JOURNAL. 2023;29:210-211
In situ sequencing of single cells elucidates spatial and temporal dynamics of lesions and normal-appearing inflammatory pathology in experimental autoimmune encephalomyelitis and multiple sclerosis
Kukanja P; Langseth C; Kirby L; Yokota C; Raman A; Hilscher M; Agirre E; Avenel C; Tiklova K; Cacais AOG; Olsson T; Nilsson M; Castelo-Branco G
Review: SEMINARS IN CELL AND DEVELOPMENTAL BIOLOGY. 2021;116:45-52
Crossing boundaries: Interplay between the immune system and oligodendrocyte lineage cells
Kirby L; Castelo-Branco G

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