Lena Ström

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Articles

Article: NATURE COMMUNICATIONS. 2024;15(1):1454
A system for inducible mitochondria-specific protein degradation in vivo
Sanyal S; Kouznetsova A; Strom L; Bjorkegren C
Article: LIFE SCIENCE ALLIANCE. 2022;5(5):e202101244
Recruitment of Scc2/4 to double-strand breaks depends on γH2A and DNA end resection
Scherzer M; Giordano F; Ferran MS; Strom L
Article: PLOS GENETICS. 2021;17(9):e1009763
Deficiency of Polη in Saccharomyces cerevisiae reveals the impact of transcription on damage-induced cohesion
Wu P-S; Grosser J; Cameron DP; Baranello L; Strom L
Article: GENETICS. 2020;216(4):1009-1022
Post-translational Regulation of DNA Polymerase η, a Connection to Damage-Induced Cohesion in Saccharomyces cerevisiae
Wu P-S; Enervald E; Joelsson A; Palmberg C; Rutishauser D; Hallberg BM; Strom L
Article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2018;141(1):408-411.e8
Reduced immunoglobulin gene diversity in patients with Cornelia de Lange syndrome
Bjorkman A; Du L; van der Burg M; Cormier-Daire V; Borck G; Pie J; Anderlid B-M; Hammarstrom L; Strom L; de Villartay J-P; Kipling D; Walters DD; Pan-Hammarstrom Q
Article: JOURNAL OF CELL SCIENCE. 2017;130(6):1134-1146
Independent mechanisms recruit the cohesin loader protein NIPBL to sites of DNA damage
Bot C; Pfeiffer A; Giordano F; Manjeera DE; Dantuma NP; Strom L
Article: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2017;18(3):E481-481
mRNA Quantification of NIPBL Isoforms A and B in Adult and Fetal Human Tissues, and a Potentially Pathological Variant Affecting Only Isoform A in Two Patients with Cornelia de Lange Syndrome
Puisac B; Teresa-Rodrigo M-E; Hernandez-Marcos M; Baquero-Montoya C; Gil-Rodriguez M-C; Visnes T; Bot C; Gomez-Puertas P; Kaiser FJ; Ramos FJ; Strom L; Pie J
Article: HUMAN MUTATION. 2015;36(4):454-462
De Novo Heterozygous Mutations in SMC3 Cause a Range of Cornelia de Lange Syndrome-Overlapping Phenotypes
Gil-Rodriguez MC; Deardorff MA; Ansari M; Tan CA; Parenti I; Baquero-Montoya C; Ousager LB; Puisac B; Hernandez-Marcos M; Esperanza Teresa-Rodrigo M; Marcos-Alcalde I; Wesselink J-J; Lusa-Bernal S; Bijlsma EK; Braunholz D; Bueno-Martinez I; Clark D; Cooper NS; Curry CJ; Fisher R; Fryer A; Ganesh J; Gervasini C; Gillessen-Kaesbach G; Guo Y; Hakonarson H; Hopkin RJ; Kaur M; Keating BJ; Kibaek M; Kinning E; Kleefstra T; Kline AD; Kuchinskaya E; Larizza L; Li YR; Liu X; Mariani M; Picker JD; Pie A; Pozojevic J; Queralt E; Richer J; Roeder E; Sinha A; Scott RH; So J; Wusik KA; Wilson L; Zhang J; Gomez-Puertas P; Casale CH; Stroem L; Selicorni A; Ramos FJ; Jackson LG; Krantz ID; Das S; Hennekam RCM; Kaiser FJ; FitzPatrick DR; Pie J
Article: JOURNAL OF IMMUNOLOGY. 2014;193(9):4732-4738
A Novel Mouse Model for the Hyper-IgM Syndrome: A Spontaneous Activation-Induced Cytidine Deaminase Mutation Leading to Complete Loss of Ig Class Switching and Reduced Somatic Hypermutation
Dahlberg CIM; He M; Visnes T; Torres ML; Cortizas EM; Verdun RE; Westerberg LS; Severinson E; Stroem L
Article: NATURE NEUROSCIENCE. 2014;17(6):801-803
The age and genomic integrity of neurons after cortical stroke in humans
Huttner HB; Bergmann O; Salehpour M; Racz A; Tatarishvili J; Lindgren E; Csonka T; Csiba L; Hortobagyi T; Mehes G; Englund E; Solnestam BW; Zdunek S; Scharenberg C; Strom L; Stahl P; Sigurgeirsson B; Dahl A; Schwab S; Possnert G; Bernard S; Kokaia Z; Lindvall O; Lundeberg J; Frisen J
Article: CHROMOSOMA. 2014;123(3):239-252
Localisation of the SMC loading complex Nipbl/Mau2 during mammalian meiotic prophase I
Visnes T; Giordano F; Kuznetsova A; Suja JA; Lander AD; Calof AL; Strom L
Article: CELL CYCLE. 2014;13(23):3645-3658
Inactivation of the budding yeast cohesin loader Scc2 alters gene expression both globally and in response to a single DNA double strand break
Lindgren E; Hagg S; Giordano F; Bjorkegren J; Strom L
Article: JOURNAL OF EXPERIMENTAL MEDICINE (JEM). 2013;210(12):2503-2513
A regulatory role for the cohesin loader NIPBL in nonhomologous end joining during immunoglobulin class switch recombination
Enervald E; Du L; Visnes T; Bojrkman A; Lindgren E; Wincent J; Borck G; Colleaux L; Cormier-Daire V; van Gent DC; Pie J; Puisac B; de Miranda NFCC; Kracker S; Hammarstrom L; de Villartay J-P; Durandy A; Schoumans J; Strom L; Pan-Hammarstrom Q
Article: PLOS GENETICS. 2013;9(1):e1003158
Importance of Polη for Damage-Induced Cohesion Reveals Differential Regulation of Cohesion Establishment at the Break Site and Genome-Wide
Enervald E; Lindgren E; Katou Y; Shirahige K; Strom L
Article: NATURE. 2011;471(7338):392-396
Chromosome length influences replication-induced topological stress
Kegel A; Betts-Lindroos H; Kanno T; Jeppsson K; Strom L; Katou Y; Itoh T; Shirahige K; Sjogren C
Article: SCIENCE. 2007;317(5835):242-245
Postreplicative formation of cohesion is required for repair and induced by a single DNA break
Stroem L; Karlsson C; Betts Lindroos H; Wedahl S; Katou Y; Shirahige K; Sjoegren C
Article: CURRENT OPINION IN CELL BIOLOGY. 2007;19(3):344-349
Chromosome segregation and double-strand break repair -: a complex connection
Strom L; Sjogren C
Article: MOLECULAR CELL. 2006;22(6):755-767
Chromosomal association of the Smc5/6 complex reveals that it functions in differently regulated pathways
Lindroos HB; Ström L; Itoh T; Katou Y; Shirahige K; Sjögren C
Article: CELL CYCLE. 2005;4(4):536-539
DNA damage-induced cohesion
Ström L; Sjögren C
Article: MOLECULAR CELL. 2004;16(6):1003-1015
Postreplicative recruitment of cohesin to double-strand breaks is required for DNA repair
Ström L; Lindroos HB; Shirahige K; Sjögren C
Article: MOLECULAR IMMUNOLOGY. 2003;39(13):771-782
Binding of Ikaros to germline Ig heavy chain γ1 and ε promoters
Ström L; Lundgren M; Severinson E
Article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 1999;49(5):523-532
Characterization of CD40-dependent immunoglobulin class switching
Ström L; Laurencikiené J; Miskiniené A; Severinson E
Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 1996;26(12):2911-2915
CD40 signaling induces interleukin-4-independent IgE switching in vivo
Ferlin WG; Severinson E; Strom L; Heath AW; Coffman RL; Ferrick DA; Howard MC
Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 1995;25(7):2042-2051
CELL-CYCLE REGULATION OF IMMUNOGLOBULIN CLASS SWITCH RECOMBINATION AND GERM-LINE TRANSCRIPTION - POTENTIAL ROLE OF ETS FAMILY MEMBERS
LUNDGREN M; STROM L; BERGQUIST LO; SKOG S; HEIDEN T; STAVNEZER J; SEVERINSON E
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All other publications

Review: CURRENT BIOLOGY. 2012;22(7):R240-R250
The Ancient and Evolving Roles of Cohesin in Gene Expression and DNA Repair
Dorsett D; Strom L
Other: CELL CYCLE. 2010;9(18):3644
Additional proof for the importance of Eco1 for DNA double strand break repair
Strom L
Review: EXPERIMENTAL CELL RESEARCH. 2010;316(9):1445-1453
S-phase and DNA damage activated establishment of Sister chromatid cohesion-importance for DNA repair
Sjogren C; Strom L
Thesis / dissertation: 2002
Regulation of the murine immunoglobulin GL gamma-1 and epsilon promoters
Ström, Lena

Employments

Senior Lecturer, Department of Cell and Molecular Biology, Karolinska Institutet, 2017-

Degrees and Education

Docent, Karolinska Institutet, 2015
Doctor Of Philosophy, Department of Cell and Molecular Biology, Karolinska Institutet, 2002

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