Laia Gorchs

Publications
CV
Public outreach and news

Articles

Article: CANCER RESEARCH COMMUNICATIONS. 2024;4(2):460-474
Exhausted Tumor-infiltrating CD39⁺CD103⁺ CD8⁺ T Cells Unveil Potential for Increased Survival in Human Pancreatic Cancer
Gorchs L; Fernandez-Moro C; Asplund E; Oosthoek M; Solders M; Ghorbani P; Sparrelid E; Rangelova E; Lohr MJ; Kaipe H
Article: CANCERS. 2022;14(15):3826
Chemokine Receptor Expression on T Cells Is Modulated by CAFs and Chemokines Affect the Spatial Distribution of T Cells in Pancreatic Tumors
Gorchs L; Oosthoek M; Yucel-Lindberg T; Moro CF; Kaipe H
Article: SCIENTIFIC REPORTS. 2020;10(1):17444
The vitamin D analogue calcipotriol promotes an anti-tumorigenic phenotype of human pancreatic CAFs but reduces T cell mediated immunity
Gorchs L; Ahmed S; Mayer C; Knauf A; Moro CF; Svensson M; Heuchel R; Rangelova E; Bergman P; Kaipe H
Article: STEM CELL REPORTS. 2020;14(4):648-662
Generation of Retinal Pigment Epithelial Cells Derived from Human Embryonic Stem Cells Lacking Human Leukocyte Antigen Class I and II
Petrus-Reurer S; Winblad N; Kumar P; Gorchs L; Chrobok M; KathleenWagner A; Bartuma H; Lardner E; Aronsson M; Reyes AP; Andre H; Alici E; Kaipe H; Kvanta A; Lanner F
Article: METHODS IN MOLECULAR BIOLOGY. 2020;2098:55-70
Isolation of Immune Cells from Placental Tissues and Phenotypic and Functional Analysis of MAIT Cells.
Solders M; Gorchs L; Kaipe H
Article: AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY. 2019;82(3):e13154
Mature naive B cells are retained in the placental intervillous blood and positively associate with specific chemokines in full-term healthy pregnancy
Solders M; Lundell A-C; Gorchs L; Gidlof S; Tiblad E; Kaipe H
Article: FRONTIERS IN IMMUNOLOGY. 2019;10:1300
Recruitment of MAIT Cells to the Intervillous Space of the Placenta by Placenta-Derived Chemokines
Solders M; Gorchs L; Tiblad E; Gidlof S; Leeansyah E; Dias J; Sandberg JK; Magalhaes I; Lundell A-C; Kaipe H
Article: FRONTIERS IN IMMUNOLOGY. 2019;10:847
Human Pancreatic Carcinoma-Associated Fibroblasts Promote Expression of Co-inhibitory Markers on CD4⁺ and CD8⁺ T-Cells
Gorchs L; Moro CF; Bankhead P; Kern KP; Sadeak I; Meng Q; Rangelova E; Kaipe H
Article: FRONTIERS IN IMMUNOLOGY. 2017;8:1861
Mucosal-associated invariant T cells Display a Poor reconstitution and altered Phenotype after allogeneic hematopoietic stem cell Transplantation
Solders M; Erkers T; Gorchs L; Poiret T; Remberger M; Magalhaes I; Kaipe H
Article: SCIENTIFIC REPORTS. 2017;7(1):6123
MAIT cells accumulate in placental intervillous space and display a highly cytotoxic phenotype upon bacterial stimulation
Solders M; Gorchs L; Erkers T; Lundell A-C; Nava S; Gidlof S; Tiblad E; Magalhaes I; Kaipe H
Article: STEM CELLS INTERNATIONAL. 2017;2017:8010961-15
Maternal Adaptive Immune Cells in Decidua Parietalis Display a More Activated and Coinhibitory Phenotype Compared to Decidua Basalis
Solders M; Gorchs L; Gidlof S; Tiblad E; Lundell A-C; Kaipe H
Article: FRONTIERS IN ONCOLOGY. 2015;5:87
Cancer-associated fibroblasts from lung tumors maintain their immunosuppressive abilities after high-dose irradiation.
Gorchs L; Hellevik T; Bruun J-A; Camilio K-A; Al-Saad S; Stuge T-B; Martinez-Zubiaurre I

All other publications

Doctoral thesis: 2022
Cancer associated fibroblasts and T cells in pancreatic cancer : an immune perspective
Gorchs L
Review: CANCERS. 2021;13(12):2995
Interactions between Cancer-Associated Fibroblasts and T Cells in the Pancreatic Tumor Microenvironment and the Role of Chemokines
Gorchs L; Kaipe H

Employments

Affiliated to Research, Department of Laboratory Medicine, Karolinska Institutet, 2026-2029
Postdoctoral Researcher, Department of Laboratory Medicine, Karolinska Institutet, 2022-2026

Degrees and Education

Degree Of Doctor Of Philosophy, Department of Laboratory Medicine, Karolinska Institutet, 2022

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