Konstantinos Ampatzis

Konstantinos Ampatzis

Principal Researcher | Docent
Visiting address: Solnavägen 9, Biomedicum kvarter B4, 17177 Solna
Postal address: C4 Neurovetenskap, C4 Forskning Ampatzis, 171 77 Stockholm

Articles

All other publications

Grants

  • Neuronal neurotransmitter plasticity: a noninvasive approach to preventing degeneration
    Swedish Research Council
    1 January 2021 - 31 December 2024
  • Swedish Research Council
    1 December 2020 - 30 November 2026
    An essential determinant of a neuron’s functionality is its neurotransmitter phenotype. While the prevailing view is that neurotransmitters are fixed and determined during development, our previous work in zebrafish supports a growing body of evidence suggests that neurons retain the ability to switch between different neurotransmitters. In the context of this research proposal, we will address the critical question: Do changes in neurotransmission can contribute to spinal cord regeneration after the injury? The architecture, connectivity, and plasticity of spinal circuits may hold the answer to this fundamental question. For this, we will take a multidisciplinary approach that combines an innovative and comprehensive set of state-of-the-art techniques from systems neuroscience and the stem cell research fields, in adult zebrafish. An animal model with extensive regeneration capacity providing an experimentally tractable system for electrophysiology, pharmacology, anatomy, molecular profiling, and genetics. By a combination of these methods, we will explore the neuronal and non-neuronal functions of spinal neurotransmission and its dynamics during spinal cord restoration. We expect our results to reveal new principles of neuroplasticity with a significant impact on our understanding of the normal and pathological state of the central nervous system. Hence, our overall objective is to promote spinal cord regeneration and reinstate normal locomotor behavior.
  • Cerebellum, Simple System with Complex Functions inHealth and Disease: New Roles of the Cerebellum in Pathophysiology of Autism
    Brain & Behavior Research Foundation
    15 January 2018 - 14 January 2020
  • Swedish Research Council
    1 January 2012 - 31 December 2013

Employments

  • Principal Researcher, Department of Neuroscience, Karolinska Institutet, 2022-
  • Researcher, Department of Neuroscience, Karolinska Institutet, 2020-2022
  • Assistant Professor, Department of Neuroscience, Karolinska Institutet, 2016-2019

Degrees and Education

  • Docent, Karolinska Institutet, 2022

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