Konstantin Barylyuk

Publications
Public outreach and news

Articles

Article: NATURE COMMUNICATIONS. 2023;14(1):2167
Stable endocytic structures navigate the complex pellicle of apicomplexan parasites
Koreny L; Mercado-Saavedra BN; Klinger CM; Barylyuk K; Butterworth S; Hirst J; Rivera-Cuevas Y; Zaccai NR; Holzer VJC; Klingl A; Dacks JB; Carruthers VB; Robinson MS; Gras S; Waller RF
Article: CELL HOST & MICROBE. 2023;31(4):650-664.e6
Cryptosporidium uses multiple distinct secretory organelles to interact with and modify its host cell
Guerin A; Strelau KM; Barylyuk K; Wallbank BA; Berry L; Crook OM; Lilley KS; Waller RF; Striepen B
Article: MSPHERE. 2021;6(5):e0061421-10.1128/msphere.00621
A Prioritized and Validated Resource of Mitochondrial Proteins in Plasmodium Identifies Unique Biology.
van Esveld SL; Meerstein-Kessel L; Boshoven C; Baaij JF; Barylyuk K; Coolen JPM; van Strien J; Duim RAJ; Dutilh BE; Garza DR; Letterie M; Proellochs NI; de Ridder MN; Venkatasubramanian PB; de Vries LE; Waller RF; Kooij TWA; Huynen MA
Article: TALANTA. 2021;224:121917
Aptamer-ligand recognition studied by native ion mobility-mass spectrometry
Daems E; Dewaele D; Barylyuk K; De Wael K; Sobott F
Article: PLOS BIOLOGY. 2021;19(3):e3001081
Molecular characterization of the conoid complex in Toxoplasma reveals its conservation in all apicomplexans, including Plasmodium species
Koreny L; Zeeshan M; Barylyuk K; Tromer EC; van Hooff JJE; Brady D; Ke H; Chelaghma S; Ferguson DJP; Eme L; Tewari R; Waller RF
Article: CELL HOST & MICROBE. 2020;28(5):752-766.e9
A Comprehensive Subcellular Atlas of the Toxoplasma Proteome via hyperLOPIT Provides Spatial Context for Protein Functions
Barylyuk K; Koreny L; Ke H; Butterworth S; Crook OM; Lassadi I; Gupta V; Tromer E; Mourier T; Stevens TJ; Breckels LM; Pain A; Lilley KS; Waller RF
Article: CHEMICAL SCIENCE. 2018;9(27):5976-5986
Aryl bis-sulfonamides bind to the active site of a homotrimeric isoprenoid biosynthesis enzyme IspF and extract the essential divalent metal cation cofactor
Root K; Barylyuk K; Schwab A; Thelemann J; Illarionov B; Geist JG; Graewert T; Bacher A; Fischer M; Diederich F; Zenobi R
Article: JOURNAL OF THE AMERICAN CHEMICAL SOCIETY. 2018;140(24):7486-7497
Native Electrospray Ionization Mass Spectrometry Reveals Multiple Facets of Aptamer-Ligand Interactions: From Mechanism to Binding Constants
Gulbakan B; Barylyuk K; Schneider P; Pillong M; Schneider G; Zenobi R
Article: ANALYTICAL CHEMISTRY. 2018;90(9):5521-5528
Charge-State-Dependent Variation of Signal Intensity Ratio between Unbound Protein and Protein-Ligand Complex in Electrospray Ionization Mass Spectrometry: The Role of Solvent-Accessible Surface Area
Chingin K; Barylyuk K
Article: JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY. 2017;28(9):1863-1875
Insight into Signal Response of Protein Ions in Native ESI-MS from the Analysis of Model Mixtures of Covalently Linked Protein Oligomers
Root K; Wittwer Y; Barylyuk K; Anders U; Zenobi R
Article: PLOS ONE. 2017;12(9):e0185109
Spontaneous non-canonical assembly of CcmK hexameric components from β-carboxysome shells of cyanobacteria
Garcia-Alles LF; Lesniewska E; Root K; Aubry N; Pocholle N; Mendoza CI; Bourillot E; Barylyuk K; Pompon D; Zenobi R; Reguera D; Truan G
Article: PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY A-MATHEMATICAL PHYSICAL AND ENGINEERING SCIENCES. 2016;374(2079):20150377
On the preservation of non-covalent protein complexes during electrospray ionization
Chingin K; Barylyuk K; Chen H
Article: JOURNAL OF THE AMERICAN CHEMICAL SOCIETY. 2016;138(3):846-856
Dynamic Assembly and Disassembly of Functional β-Endorphin Amyloid Fibrils
Nespovitaya N; Gath J; Barylyuk K; Seuring C; Meier BH; Riek R
Article: CHEMMEDCHEM. 2015;10(12):2090-2098
Aryl Bis-Sulfonamide Inhibitors of IspF from Arabidopsis thaliana and Plasmodium falciparum
Thelemann J; Illarionov B; Barylyuk K; Geist J; Kirchmair J; Schneider P; Anthore L; Root K; Trapp N; Bacher A; Witschel M; Zenobi R; Fischer M; Schneider G; Diederich F
Article: JOURNAL OF ANALYTICAL CHEMISTRY. 2014;69(13):1215-1219
Ion mobility spectrometry coupled to laser-induced fluorescence for probing the electronic structure and conformation of gas-phase ions
Frankevich VE; Barylyuk KV; Sinues PM-L; Zenobi R
Article: PROTEIN EXPRESSION AND PURIFICATION. 2014;99:78-86
The production of recombinant ¹⁵N, ¹³C-labelled somatostatin 14 for NMR spectroscopy
Nespovitaya N; Barylyuk K; Eichmann C; Zenobi R; Riek R
Article: PHYSICAL CHEMISTRY CHEMICAL PHYSICS. 2014;16(19):8911-8920
Fluorescence resonance energy transfer of gas-phase ions under ultra high vacuum and ambient conditions
Frankevich V; Chagovets V; Widjaja F; Barylyuk K; Yang Z; Zenobi R
Article: ACS CHEMICAL BIOLOGY. 2014;9(1):218-226
Determination of Protein-Ligand Binding Constants of a Cooperatively Regulated Tetrameric Enzyme Using Electrospray Mass Spectrometry
Cubrilovic D; Haap W; Barylyuk K; Ruf A; Badertscher M; Gubler M; Tetaz T; Joseph C; Benz J; Zenobi R
Article: CHEMICAL SCIENCE. 2014;5(7):2794-2803
Direct monitoring of protein-protein inhibition using nano electrospray ionization mass spectrometry
Cubrilovic D; Barylyuk K; Hofmann D; Walczak MJ; Graeber M; Berg T; Wider G; Zenobi R
Article: CHIMIA. 2014;68(3):119-123
Mass Spectrometry Research at the Laboratory for Organic Chemistry, ETH Zurich
Barylyuk K; Frankevich V; Ibanez AJ; Sinues PM-L; Zenobi R
Article: ANALYTICAL CHEMISTRY. 2013;85(24):11902-11912
DNA Oligonucleotides: A Model System with Tunable Binding Strength to Study Monomer-Dimer Equilibria with Electrospray Ionization-Mass Spectrometry
Barylyuk K; Guelbakan B; Xie X; Zenobi R
Article: JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY. 2013;24(9):1396-1404
Mass Discrimination in High-Mass MALDI-MS
Weidmann S; Mikutis G; Barylyuk K; Zenobi R
Article: CHEMPHYSCHEM. 2013;14(5):929-935
Native Biomolecules in the Gas Phase? The Case of Green Fluorescent Protein
Frankevich V; Barylyuk K; Chingin K; Nieckarz R; Zenobi R
Article: ANALYTICAL CHEMISTRY. 2013;85(6):3425-3432
A New, Modular Mass Calibrant for High-Mass MALDI-MS
Weidmann S; Barylyuk K; Nespovitaya N; Maedler S; Zenobi R
Article: ANALYTICAL CHEMISTRY. 2013;85(1):39-43
Ion Mobility Spectrometry Coupled to Laser-Induced Fluorescence
Frankevich V; Sinues PM-L; Barylyuk K; Zenobi R
Article: RAPID COMMUNICATIONS IN MASS SPECTROMETRY. 2012;26(13):1567-1572
Probing the mechanisms of ambient ionization by laser-induced fluorescence spectroscopy
Frankevich V; Nieckarz RJ; Sagulenko PN; Barylyuk K; Zenobi R; Levitsky LI; Agapov AY; Perlova TY; Gorshkov MV; Tarasova IA
Article: JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY. 2012;23(2):213-224
Compelling Advantages of Negative Ion Mode Detection in High-Mass MALDI-MS for Homomeric Protein Complexes
Maedler S; Barylyuk K; Erba EB; Nieckarz RJ; Zenobi R
Article: RSC ADVANCES. 2012;2(5):1962-1969
Gas-phase basicity of several common MALDI matrices measured by a simple experimental approach
Barylyuk K; Fritsche L; Balabin RM; Nieckarz R; Zenobi R
Article: ANALYTICAL CHEMISTRY. 2011;83(24):9251-9259
Quantifying Protein-Protein Interactions Within Noncovalent Complexes Using Electrospray Ionization Mass Spectrometry
Erba EB; Barylyuk K; Yang Y; Zenobi R
Article: JOURNAL OF THE AMERICAN CHEMICAL SOCIETY. 2011;133(35):13957-13966
Hexameric Supramolecular Scaffold Orients Carbohydrates To Sense Bacteria
Gruenstein D; Maglinao M; Kikkeri R; Collot M; Barylyuk K; Lepenies B; Kamena F; Zenobi R; Seeberger PH
Article: INTERNATIONAL JOURNAL OF MASS SPECTROMETRY. 2011;306(2-3):241-245
Absorption of the green fluorescent protein chromophore anion in the gas phase studied by a combination of FTICR mass spectrometry with laser-induced photodissociation spectroscopy
Chingin K; Balabin RM; Frankevich V; Barylyuk K; Nieckarz R; Sagulenko P; Zenobi R
Article: JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY. 2011;22(7):1167-1177
What Happens to Hydrophobic Interactions during Transfer from the Solution to the Gas Phase? The Case of Electrospray-Based Soft Ionization Methods
Barylyuk K; Balabin RM; Gruenstein D; Kikkeri R; Frankevich V; Seeberger PH; Zenobi R
Article: PHYSICAL CHEMISTRY CHEMICAL PHYSICS. 2010;12(42):14121-14127
Optical properties of protonated Rhodamine 19 isomers in solution and in the gas phase
Chingin K; Balabin RM; Frankevich V; Chen H; Barylyuk K; Nieckarz R; Fedorov A; Zenobi R
Article: PHYSICAL CHEMISTRY CHEMICAL PHYSICS. 2010;12(37):11710-11714
Rhodamines in the gas phase: cations, neutrals, anions, and adducts with metal cations
Chingin K; Balabin RM; Barylyuk K; Chen H; Frankevich V; Zenobi R
Article: ANGEWANDTE CHEMIE-INTERNATIONAL EDITION. 2010;49(13):2358-2361
Direct Access to Isolated Biomolecules under Ambient Conditions
Chingin K; Frankevich V; Balabin RM; Barylyuk K; Chen H; Wang R; Zenobi R
Article: JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY. 2010;21(1):172-177
Fragmentation of Benzylpyridinium "Thermometer" Ions and Its Effect on the Accuracy of Internal Energy Calibration
Barylyuk KV; Chingin K; Balabin RM; Zenobi R
Article: BIOORGANICHESKAYA KHIMIYA. 2009;35(4):457-470
Proteomic Analysis of Mitochondria from the Bos taurus Heart. II. Identification of Mitochondrial Soluble Proteins
Dainichenko EV; Boldyrev AN; Barylyuk KV; Polyakov NB; Grinkevich VA
Article: RUSSIAN JOURNAL OF BIOORGANIC CHEMISTRY. 2009;35(1):33-46
Proteomic analysis of heart mitochondria from Bos taurus: I. Application of proteomic methods to identification of transmembrane domains of proteins of the internal mitochondrial membrane
Polyakov NB; Barylyuk KV; Frankevich VE; Grinkevich VA
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Review: CURRENT OPINION IN BIOTECHNOLOGY. 2015;31:65-72
Determination of thermodynamic and kinetic properties of biomolecules by mass spectrometry
Guelbakan B; Barylyuk K; Zenobi R

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