Klas Bratteby

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About me

Dr. Bratteby recieved his MSc degree in civil engineering in biotechnology from the Faculty of engineering at Lund University in 2017. After this, he proceeded to do his Ph.D. in Matthias Herth’s research group at the University of Copenhagen, focusing on 18F-radiolabeling of base-sensitive compounds and pretargeting.
After receiving his PhD. in 2021 he worked for one year at the cyclotron unit and Lund University Hospital before joining the Tran lab at Karolinska in 2022 as a postdoc and as a R&
D radiochemist at Theranostics Trial Center. His current main postdoctoral project is developing TROP2-targeted theranostics.

Articles

Article: EJNMMI RADIOPHARMACY AND CHEMISTRY. 2024;9(1):35
GMP production of [18F]FE-PE2I on a TRACERLab FX2 N synthesis module, a radiotracer for in vivo PET imaging of the dopamine transport.
Ferrat M; Moein MM; Cananau C; Tegnebratt T; Saliba P; Norman F; Steiger C; Bratteby K; Samén E; Dahl K; Tran TA
Journal article: EJNMMI RADIOPHARMACY AND CHEMISTRY. 2024;9(1):35
GMP production of [¹⁸F]FE-PE2I on a TRACERLab FX2 N synthesis module, a radiotracer for in vivo PET imaging of the dopamine transport
Ferrat M; Moein MM; Cananau C; Tegnebratt T; Saliba P; Norman F; Steiger C; Bratteby K; Samen E; Dahl K; Tran TA
Article: EJNMMI RADIOPHARMACY AND CHEMISTRY. 2023;8(1):41
Optimized, automated and cGMP-compliant synthesis of the HER2 targeting [⁶⁸Ga]Ga-ABY-025 tracer
Jussing E; Ferrat M; Moein MM; Alfredeen H; Tegnebratt T; Bratteby K; Samen E; Feldwisch J; Altena R; Axelsson R; Tran TA
Article: NATURE COMMUNICATIONS. 2023;14(1):6750
The α-synuclein PET tracer [18F] ACI-12589 distinguishes multiple system atrophy from other neurodegenerative diseases
Smith R; Capotosti F; Schain M; Ohlsson T; Vokali E; Molette J; Touilloux T; Hliva V; Dimitrakopoulos IK; Puschmann A; Jogi J; Svenningsson P; Andreasson M; Sandiego C; Russell DS; Miranda-Azpiazu P; Halldin C; Stomrud E; Hall S; Bratteby K; Tampio L'Estrade E; Luthi-Carter R; Pfeifer A; Kosco-Vilbois M; Streffer J; Hansson O
Journal article: ALZHEIMERS & DEMENTIA. 2022;18(S6)
Initial clinical scans using [18F]ACI‐12589, a novel α‐synuclein PET‐tracer
Smith R; Capotosti F; Schain M; Ohlsson T; Touilloux T; Hliva V; Vokali E; Luthi‐Carter R; Molette J; Dimitrakopoulos IK; Jögi J; Stomrud E; Hall S; Bratteby K; Tampio E; Pfeifer A; Kosco‐Vilbois M; Streffer J; Hansson O
Article: PHARMACEUTICALS. 2022;15(2):245
Development of 18F-Labeled Bispyridyl Tetrazines for In Vivo Pretargeted PET Imaging.
García-Vázquez R; Jørgensen JT; Bratteby KE; Shalgunov V; Hvass L; Herth MM; Kjær A; Battisti UM
Article: JOURNAL OF MEDICINAL CHEMISTRY. 2021;64(20):15297-15312
Development of the First Aliphatic ¹⁸F-Labeled Tetrazine Suitable for Pretargeted PET Imaging.Expanding the Bioorthogonal Tool Box
Battisti UM; Bratteby K; Jorgensen JT; Hvass L; Shalgunov V; Mikula H; Kjaer A; Herth MM
Article: ACS PHARMACOLOGY AND TRANSLATIONAL SCIENCE. 2021;4(5):1556-1566
Insights into Elution of Anion Exchange Cartridges: Opening the Path toward Aliphatic ¹⁸F-Radiolabeling of Base-Sensitive Tracers
Bratteby K; Shalgunov V; Battisti UM; Petersen IN; van den Broek SL; Ohlsson T; Gillings N; Erlandsson M; Herth MM
Article: PHARMACEUTICALS. 2021;14(7):601
Fully Automated GMP-Compliant Synthesis of [¹⁸F]FE-PE2I
Bratteby K; Denholt CL; Lehel S; Petersen IN; Madsen J; Erlandsson M; Ohlsson T; Herth MM; Gillings N
Article: ACS PHARMACOLOGY AND TRANSLATIONAL SCIENCE. 2021;4(2):824-833
Lipophilicity and Click Reactivity Determine the Performance of Bioorthogonal Tetrazine Tools in Pretargeted In Vivo Chemistry
Steen EJL; Jorgensen JT; Denk C; Battisti UM; Norregaard K; Edem PE; Bratteby K; Shalgunov V; Wilkovitsch M; Svatunek D; Poulie CBM; Hvass L; Simon M; Wanek T; Rossin R; Robillard M; Kristensen JL; Mikula H; Kjaer A; Herth MM
Article: JOURNAL OF MEDICINAL CHEMISTRY. 2020;63(2):747-755
In Vivo Veritas: ¹⁸F-Radiolabeled Glycomimetics Allow Insights into the Pharmacological Fate of Galectin-3 Inhibitors
Bratteby K; Torkelsson E; L'Estrade ET; Peterson K; Shalgunov V; Xiong M; Leffler H; Zetterberg FR; Olsson TG; Gillings N; Nilsson UJ; Herth MM; Erlandsson M
Article: JOURNAL OF IMMUNOLOGY. 2016;197(8):3415-3424
Quantitative Mass Spectrometry To Study Inflammatory Cartilage Degradation and Resulting Interactions with the Complement System
Furst CM; Ahrman E; Bratteby K; Waldemarson S; Malmstrom J; Blom AM

All other publications

Review: CHEMMEDCHEM. 2021;16(17):2612-2622
Aliphatic ¹⁸F-Radiofluorination: Recent Advances in the Labeling of Base-Sensitive Substrates**
Bratteby K; Shalgunov V; Herth MM

Employments

Research Specialist, Department of Oncology-Pathology, Karolinska Institutet, 2025-2025
Affiliated to Research, Department of Oncology-Pathology, Karolinska Institutet, 2022-2025

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