Klara Asplund Högelin

Publications
CV
Public outreach and news

Articles

Article: ANTIBODIES. 2024;13(4):102
Intensity of Intrathecal Total IgG Synthesis in Multiple Sclerosis Correlates with the Degree of Pleocytosis, Diversity of Intrathecal Antiviral Antibody Specificities, and Female Sex
Vlad B; Hilty M; Neidhart S; Hoegelin KA; Ziegler M; Khademi M; Lutterotti A; Regeniter A; Martin R; Al Nimer F; Jelcic I
Article: MULTIPLE SCLEROSIS JOURNAL. 2024;30(13):1598-1608
Intrathecal immune reactivity against Measles-, Rubella-, and Varicella Zoster viruses is associated with cerebrospinal fluid inflammation in multiple sclerosis
Vlad B; Neidhart S; Hilty M; Hogelin KA; Reichen I; Ziegler M; Khademi M; Lutterotti A; Regeniter A; Martin R; Al Nimer F; Jelcic I
Article: ANNALS OF NEUROLOGY. 2024;95(6):1112-1126
HLA Associations of Intrathecal IgG Production against Specific Viruses in Multiple Sclerosis
Neidhart S; Vlad B; Hilty M; Hogelin KA; Ziegler M; Berenjeno-Correa E; Reichen I; Stridh P; Jelcic I; Khademi M; Kockum I; Sospedra M; Al Nimer F; Martin R; Jelcic I
Article: CLINICAL IMMUNOLOGY. 2024;258:109870
B cell activating factor levels are linked to distinct B cell markers in multiple sclerosis and following B cell depletion and repopulation
Hogelin KA; Isac B; Khademi M; Al Nimer F
Article: EUROPEAN JOURNAL OF NEUROLOGY. 2023;30(12):3789-3798
The impact of hybrid immunity on immune responses after SARS-CoV-2 vaccination in persons with multiple sclerosis treated with disease-modifying therapies
Rabenstein M; Thomas OG; Carlin G; Khademi M; Hogelin KA; Malmestrom C; Axelsson M; Brandt AF; Gafvelin G; Gronlund H; Kockum I; Piehl F; Lycke J; Olsson T; Hessa T
Article: EUROPEAN JOURNAL OF NEUROLOGY. 2022;29(11):3317-3328
B-cell repopulation dynamics and drug pharmacokinetics impact SARS-CoV-2 vaccine efficacy in anti-CD20-treated multiple sclerosis patients
Hogelin KA; Ruffin N; Pin E; Hober S; Nilsson P; Cucuzza CS; Khademi M; Olsson T; Piehl F; Al Nimer F
Article: SCIENCE ADVANCES. 2022;8(17):eabn1823
Identification of four novel T cell autoantigens and personal autoreactive profiles in multiple sclerosis
Bronge M; Hogelin KA; Thomas OG; Ruhrmann S; Carvalho-Queiroz C; Nilsson OB; Kaiser A; Zeitelhofer M; Holmgren E; Linnerbauer M; Adzemovic MZ; Hellstrom C; Jelcic I; Liu H; Nilsson P; Hillert J; Brundin L; Fink K; Kockum I; Tengvall K; Martin R; Tegel H; Graslund T; Al Nimer F; Guerreiro-Cacais AO; Khademi M; Gafvelin G; Olsson T; Gronlund H
Article: ISCIENCE. 2021;24(9):103078
Development of humoral and cellular immunological memory against SARS-CoV-2 despite B cell depleting treatment in multiple sclerosis
Hogelin KA; Ruffin N; Pin E; Manberg A; Hober S; Gafvelin G; Gronlund H; Nilsson P; Khademi M; Olsson T; Piehl F; Al Nimer F
Article: ALLERGY. 2019;74(8):1472-1479
Allergens in dog extracts: Implication for diagnosis and treatment
Wintersand A; Asplund K; Binnmyr J; Holmgren E; Nilsson OB; Gafvelin G; Gronlund H

All other publications

Doctoral thesis: 2024
Multiple sclerosis, viruses, and B cell depleting therapy : a meeting at the immune system
Högelin KA
Conference publication: MULTIPLE SCLEROSIS JOURNAL. 2021;27(2_SUPPL):344-345
T cell reactivity screening reveals four novel CNS autoantigens in multiple sclerosis
Bronge M; Asplund Hogelin K; Thomas OG; Ruhrmann S; Carvalho-Querioz C; Nilsson O; Kaiser A; Holmgren E; Linnerbauer M; Adzemovic MZ; Zeitelhofer M; Hellstrom C; Jelcic I; Liu H; Nilsson P; Hillert J; Brundin L; Fink K; Martin R; Tegel H; Graslund T; Al Nimer F; Guerreiro-Cacais AO; Khademi M; Gafvelin G; Olsson T; Gronlund H
Conference publication: MULTIPLE SCLEROSIS JOURNAL. 2021;27(2_SUPPL):351
No evidence of rebound MS disease activity with presence of CD20⁺ T cells at B-cell reconstitution after treatment with rituximab
Ruffin N; Asplund-Hogelin K; Khademi M; Al Nimer F; Piehl F
Preprint: SSRN ELECTRONIC JOURNAL. 2021
Development of Humoral and Cellular Immunological Memory Against SARS-CoV-2 Despite B-Cell Depleting Treatment in Multiple Sclerosis
Asplund Högelin K; Ruffin N; Pin E; Månberg A; Hober S; Gafvelin G; Grönlund H; Nilsson P; Khademi M; Olsson T; Piehl F; Al Nimer F

Employments

Affiliated to Research, Department of Laboratory Medicine, Karolinska Institutet, 2025-2028
Affiliated to Research, Department of Clinical Neuroscience, Karolinska Institutet, 2024-2025

Degrees and Education

Degree Of Doctor Of Philosophy, Department of Clinical Neuroscience, Karolinska Institutet, 2024
Degree of Master in Neurochemistry with Molecular Neurobiology, Department of Biochemistry and Biophysics, Stockholm University, 2019
Degree Of Bachelor Of Medical Science, Karolinska Institutet, 2016
Degree Of Bachelor Of Science In Biomedical Laboratory Science, Karolinska Institutet, 2016

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