Katalin Dobra
Professor/Senior Physician | Docent
E-mail: katalin.dobra@ki.se
Visiting address: BioClinicum Visionsgatan 4, 17176 SOLNA
Postal address: K7 Onkologi-Patologi, K7 Forskning Dobra, 171 77 Stockholm
About me
- I am Senior Physician and Professor of Clinical Pathology at the Department of Oncology-Pathology.
Research
- My research is about cancer of the lungs and pleurae – diseases that generally have a poor prognosis. In my research group, we study both primary cancer and metastases and our long-term goal is to help cancer patients obtain earlier and more accurate diagnoses and prognoses so that they can be given personalised treatment. The research spans the mapping of fundamental mechanisms of tumour growth to the development of new analytical methods and biomarkers.
I have a particular interest in the protein syndecan 1, which, in being involved in cell division, is relevant to tumour growth. The protein is anchored to the cell membrane, but we have made the surprising discovery that it is also found in the nucleus. We have also shown that soluble syndecan 1 in bodily fluids can be used as a biomarker for identifying aggressive tumours requiring more extensive treatment.
Articles
- Article: CYTOPATHOLOGY. 2023;34(5):456-465
- Article: HAEMATOLOGICA. 2023;108(9):2422-2434
- Article: CANCER MEDICINE. 2023;12(5):5334-5340
- Journal article: REVISTA CHILENA DE LITERATURA. 2023;(108):2422-2434
- Article: JOURNAL OF CLINICAL PATHOLOGY. 2022;75(5):302-309
- Article: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2022;23(9):4517
- Article: BIOMOLECULES. 2021;11(11):1721
- Article: BIOMOLECULES. 2021;11(11):1606
- Article: BIOLOGY. 2021;10(6):521
- Article: PATHOLOGY. 2021;53(4):446-453
- Article: CANCER CYTOPATHOLOGY. 2021;129(6):468-478
- Article: DIAGNOSTIC CYTOPATHOLOGY. 2021;49(5):606-614
- Article: CANCERS. 2021;13(4):685
- Article: CANCERS. 2021;13(4):655
- Article: ONCOTARGET. 2020;11(50):4637-4647
- Article: BIOMOLECULES. 2020;10(8):E1113-1113
- Article: BIOMOLECULES. 2020;10(7):E1034-1034
- Article: LIVER INTERNATIONAL. 2019;39(2):382-388
- Article: ARCHIVES OF PATHOLOGY AND LABORATORY MEDICINE. 2018;142(8):893-901
- Article: BMC CELL BIOLOGY. 2017;18(1):34
- Article: CANCER CYTOPATHOLOGY. 2017;125(12):908-917
- Journal article: JOURNAL OF THORACIC ONCOLOGY. 2017;12(11):s2021
- Article: ONCOTARGET. 2017;8(47):82885-82896
- Article: MATRIX BIOLOGY. 2017;59:3-22
- Article: JOURNAL OF TRANSLATIONAL MEDICINE. 2016;14(1):295
- Article: CLINICAL NUCLEAR MEDICINE. 2016;41(4):263-267
- Article: CELLULAR SIGNALLING. 2015;27(10):2054-2067
- Article: CANCER CYTOPATHOLOGY. 2015;123(8):449-453
- Article: DIAGNOSTIC CYTOPATHOLOGY. 2015;43(7):563-576
- Article: GENES AND CANCER. 2015;6(3-4):119-128
- Article: ACTA CYTOLOGICA. 2015;59(1):2-16
- Article: BMC CANCER. 2014;14:709
- Article: MOLECULAR & CELLULAR PROTEOMICS. 2014;13(3):701-715
- Article: BIOMED RESEARCH INTERNATIONAL. 2014;2014:419853-11
- Article: FRONTIERS IN ONCOLOGY. 2013;3:203
- Article: PLOS ONE. 2013;8(8):e72030
- Article: PLOS ONE. 2012;7(10):e48091
- Article: PLOS ONE. 2012;7(8):e40521
- Article: PLOS ONE. 2012;7(6):e39474
- Article: JOURNAL OF IMMUNOLOGY. 2011;187(7):3546-3554
- Article: PLOS ONE. 2011;6(6):e14816
- Article: INTERNATIONAL JOURNAL OF CANCER. 2010;127(9):1999-2008
- Article: LUNG CANCER. 2010;68(1):39-43
- Article: CELL PROLIFERATION. 2010;43(1):29-40
- Article: JOURNAL OF EXPERIMENTAL AND CLINICAL CANCER RESEARCH. 2009;28(1):92
- Article: IN VIVO. 2009;23(1):69-76
- Article: CONNECTIVE TISSUE RESEARCH. 2008;49(3-4):270-272
- Article: CONNECTIVE TISSUE RESEARCH. 2008;49(3-4):249-251
- Article: DIFFERENTIATION. 2007;75(2):123-132
- Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2006;281(46):35116-35128
- Article: FREE RADICAL BIOLOGY AND MEDICINE. 2006;41(6):874-885
- Article: CANCER LETTERS. 2006;232(2):161-169
- Article: JOURNAL OF PATHOLOGY. 2005;207(1):91-101
- Article: ANTICANCER RESEARCH. 2004;24(2B):599-603
- Article: JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS. 2004;34(4):797-801
- Article: ANTICANCER RESEARCH. 2003;23(3B):2435-2444
- Article: ANTICANCER RESEARCH. 2002;22(6C):4157-4162
- Article: EXPERIMENTAL CELL RESEARCH. 2002;274(2):235-245
- Journal article: JOURNAL OF MUSCULOSKELETAL RESEARCH. 2001;5(02):79-88
- Article: DIFFERENTIATION. 2000;66(4-5):181-188
- Article: AMERICAN JOURNAL OF CLINICAL PATHOLOGY. 2000;114(2):203-209
- Article: EXPERIMENTAL CELL RESEARCH. 2000;258(1):12-22
- Article: DIFFERENTIATION. 1999;65(2):89-96
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All other publications
- Book chapter: THE EXTRACELLULAR MATRIX AND THE TUMOR MICROENVIRONMENT: BIOLOGY OF EXTRACELLULAR MATRIX. 2022;p. 49-73
- Review: ACTA CYTOLOGICA. 2021;65(6):501-509
- Review: TRANSLATIONAL LUNG CANCER RESEARCH. 2020;9(3):934-943
- Review: CYTOPATHOLOGY. 2019;30(1):31-38
- Conference publication: JOURNAL OF HEPATOLOGY. 2018;68:S217
- Book chapter: SEROUS EFFUSIONS. 2018;p. 259-281
- Book chapter: SEROUS EFFUSIONS. 2018;p. 171-189
- Conference publication: JOURNAL OF THORACIC ONCOLOGY. 2017;12(11):S2020
- Review: PLEURA AND PERITONEUM. 2016;1(3):119-133
- Corrigendum: CELLULAR SIGNALLING. 2015;27(12):2599-2600
- Review: CYTOPATHOLOGY. 2015;26(3):142-156
- Review: CYTOJOURNAL. 2015;12:26
- Editorial comment: BIOMED RESEARCH INTERNATIONAL. 2015;2015:482879-2
- Review: DISEASE MARKERS. 2015;2015:796052-13
- Review: BIOCHIMICA ET BIOPHYSICA ACTA: INTERNATIONAL JOURNAL OF BIOCHEMISTRY AND BIOPHYSICS. 2014;1840(8):2491-2497
- Review: FRONTIERS IN ONCOLOGY. 2013;3:310
- Book chapter: SEROUS EFFUSIONS. 2012;p. 151-165
- Book chapter: SEROUS EFFUSIONS. 2012;p. 225-240
- Meeting abstract: LUNG CANCER. 2006;54:S52
- Conference publication: ANTICANCER RESEARCH. 2004;24(5D):3473
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Employments
- Professor/Senior Physician, Department of Oncology-Pathology, Karolinska Institutet, 2022-
Degrees and Education
- Docent, Karolinska Institutet, 2010
- Doctor Of Philosophy, Department of Laboratory Medicine, Karolinska Institutet, 2002