Julien Record

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About me

Post-doctoral fellow, Department of Microbiology, Tumor and Cell Biology
(MTC), Karolinska Institutet, Sweden
PhD, Biomedicine, Institute of Child Health, UCL, UK
Undergraduate education, Universite Paul Sabatier, Toulouse, France

Selected publications

Article: SCIENCE ADVANCES. 2023;9(34):eadg1610

Exposure of volunteers to microgravity by dry immersion bed over 21 days results in gene expression changes and adaptation of T cells.

Gallardo-Dodd CJ; Oertlin C; Record J; Galvani RG; Sommerauer C; Kuznetsov NV; Doukoumopoulos E; Ali L; Oliveira MMS; Seitz C; Percipalle M; Nikić T; Sadova AA; Shulgina SM; Shmarov VA; Kutko OV; Vlasova DD; Orlova KD; Rykova MP; Andersson J; Percipalle P; Kutter C; Ponomarev SA; Westerberg LS
Article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2022;149(3):1069-1084

Overactive WASp in X-linked neutropenia leads to aberrant B-cell division and accelerated plasma cell generation.

He M; Saeed MB; Record J; Keszei M; Gonçalves Pinho L; Vasconcelos-Fontes L; D'Aulerio R; Vieira R; Oliveira MMS; Geyer C; Bohaumilitzky L; Thiemann M; Deordieva E; Buedts L; Matias Lopes JP; Pershin D; Hammarström L; Xia Y; Zhao X; Cunningham-Rundles C; Thrasher AJ; Burns SO; Cotta-de-Almeida V; Liu C; Shcherbina A; Vandenberghe P; Westerberg LS
Corrigendum: JOURNAL OF CLINICAL INVESTIGATION. 2021;131(23):e156513

Constitutive activation of WASp in X-linked neutropenia renders neutrophils hyperactive.

Keszei M; Record J; Kritikou JS; Wurzer H; Geyer C; Thiemann M; Drescher P; Brauner H; Köcher L; James J; He M; Baptista MA; Dahlberg CI; Biswas A; Lain S; Lane DP; Song W; Pütsep K; Vandenberghe P; Snapper SB; Westerberg LS
Article: HAEMATOLOGICA. 2020;105(5):1339-1350

An intronic deletion in megakaryoblastic leukemia 1 is associated with hyperproliferation of B cells in triplets with Hodgkin lymphoma.

Record J; Sendel A; Kritikou JS; Kuznetsov NV; Brauner H; He M; Nagy N; Oliveira MMS; Griseti E; Haase CB; Dahlström J; Boddul S; Wermeling F; Thrasher AJ; Liu C; Andersson J; Claesson H-E; Winqvist O; Burns SO; Björkholm M; Westerberg LS
Article: BLOOD. 2015;126(13):1527-1535

Immunodeficiency and severe susceptibility to bacterial infection associated with a loss-of-function homozygous mutation of MKL1.

Record J; Malinova D; Zenner HL; Plagnol V; Nowak K; Syed F; Bouma G; Curtis J; Gilmour K; Cale C; Hackett S; Charras G; Moulding D; Nejentsev S; Thrasher AJ; Burns SO

Articles

Journal article: HEMATOLOGICAL ONCOLOGY. 2023;41(S2):605

Characterization of clonal evolution in pediatric lymphoma using single‐cell transcriptomics

D'aulerio R; Yong T; Oertlin C; Record JA; Kwiecinska A; Baecklund F; Westerberg LS
Article: JOURNAL OF LEUKOCYTE BIOLOGY. 2022;111(4):793-803

The WASp L272P gain-of-function mutation alters dendritic cell coordination of actin dynamics for migration and adhesion.

Oliveira MMS; Kung S-Y; Moreau HD; Maurin M; Record J; Sanséau D; Nylén S; Lennon-Duménil A-M; Westerberg LS
Article: JCI INSIGHT. 2021;6(6):140273

Constitutive activation of WASp leads to abnormal cytotoxic cells with increased granzyme B and degranulation response to target cells.

Kritikou JS; Oliveira MM; Record J; Saeed MB; Nigam SM; He M; Keszei M; Wagner AK; Brauner H; Sendel A; Sedimbi SK; Rentouli S; Lane DP; Snapper SB; Kärre K; Vandenberghe P; Orange JS; Westerberg LS
Article: JOURNAL OF CLINICAL INVESTIGATION. 2020;130(3):1185-1198

CD73 immune checkpoint defines regulatory NK cells within the tumor microenvironment.

Neo SY; Yang Y; Record J; Ma R; Chen X; Chen Z; Tobin NP; Blake E; Seitz C; Thomas R; Wagner AK; Andersson J; de Boniface J; Bergh J; Murray S; Alici E; Childs R; Johansson M; Westerberg LS; Haglund F; Hartman J; Lundqvist A
Article: JOURNAL OF CLINICAL INVESTIGATION. 2018;128(9):4115-4131

Constitutive activation of WASp in X-linked neutropenia renders neutrophils hyperactive.

Keszei M; Record J; Kritikou JS; Wurzer H; Geyer C; Thiemann M; Drescher P; Brauner H; Köcher L; James J; He M; Baptista MA; Dahlberg CI; Biswas A; Lane DP; Song W; Pütsep K; Vandenberghe P; Snapper SB; Westerberg LS
Article: JOURNAL OF EXPERIMENTAL MEDICINE. 2017;214(1):59-71

Autoinflammatory periodic fever, immunodeficiency, and thrombocytopenia (PFIT) caused by mutation in actin-regulatory gene WDR1.

Standing ASI; Malinova D; Hong Y; Record J; Moulding D; Blundell MP; Nowak K; Jones H; Omoyinmi E; Gilmour KC; Medlar A; Stanescu H; Kleta R; Anderson G; Nanthapisal S; Gomes SM; Klein N; Eleftheriou D; Thrasher AJ; Brogan PA
Article: HUMAN GENE THERAPY. 2016;27(9):668-678

Lentiviral Vector-Mediated Correction of a Mouse Model of Leukocyte Adhesion Deficiency Type I.

Leon-Rico D; Aldea M; Sanchez-Baltasar R; Mesa-Nuñez C; Record J; Burns SO; Santilli G; Thrasher AJ; Bueren JA; Almarza E
Journal article: PEDIATRIC RHEUMATOLOGY. 2015;13(Suppl 1):o19

Severe autoinflammatory disease caused by mutation in a gene controlling actin cytoskeletal dynamics and cure with allogeneic haematopoetic stem cell transplantation

Standing A; Malinova D; Record J; Moulding D; Blundell M; Nowak K; Jones H; Omoyinmi E; Nanthapisal S; Gomes SM; Hong Y; Klein N; Eleftheriou D; Thrasher A; Brogan P
Article: BLOOD. 2012;120(18):3803-3811

Excess F-actin mechanically impedes mitosis leading to cytokinesis failure in X-linked neutropenia by exceeding Aurora B kinase error correction capacity.

Moulding DA; Moeendarbary E; Valon L; Record J; Charras GT; Thrasher AJ
Article: FRONTIERS IN IMMUNOLOGY. 2011;2:51

Frustrated phagocytosis on micro-patterned immune complexes to characterize lysosome movements in live macrophages.

Labrousse AM; Meunier E; Record J; Labernadie A; Beduer A; Vieu C; Ben Safta T; Maridonneau-Parini I

All other publications

Review: FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY. 2021;9:682294

Journey to the Center of the Cell: Cytoplasmic and Nuclear Actin in Immune Cell Functions.

Record J; Saeed MB; Venit T; Percipalle P; Westerberg LS
Review: FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY. 2021;9

Journey to the Center of the Cell Cytoplasmic and Nuclear Actin in Immune Cell Functions

Record J; Saeed MB; Venit T; Percipalle P; Westerberg LS
Conference publication: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2021;94(6)

Overactive WASp in X-linked neutropenia leads to aberrant B-cell division and accelerated plasma cell generation

D'Aulerio R; He M; Saeed MB; Record J; Keszei M; Goncalves Pinho L; Vasconcelos-Fontes L; Vieira R; Oliveira M; Geyer C; Bohaumilitzky L; Thiemann M; Deordieva E; Buedts L; Lopes J; Pershin D; Hammarstrom L; Xia Y; Zhao X; Cunningham-Rundles C; Thrasher A; Burns S; Cotta-de-Almeida V; Liu C; Shcherbina A; Vandenberghe P; Westerberg L
Review: CHROMATIN AND GENOMIC INSTABILITY IN CANCER. 2020;356:1-97

Two sides of the coin: Cytoskeletal regulation of immune synapses in cancer and primary immune deficiencies.

Saeed MB; Record J; Westerberg LS
Conference publication: MOLECULAR BIOLOGY OF THE CELL. 2018;29(26):96

Constitutive activation of WASp renders neutrophils hyperactive.

Keszei M; Record J; Kritikou J; Brauner H; He M; Song W; Vandenberghe P; Snapper S; Westerberg L
Conference publication: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2017;86(4):283

Neutrophils with X-linked neutropenia mutations of Wiskott-Aldrich syndrome protein are hyperactive

Keszei M; Wurzer H; Record J; Drescher P; Brauner H; Kocher L; James J; Putsep K; Song W; Vandenberghe P; Snapper SB; Westerberg LS
Conference publication: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2017;86(4):341

An intronic deletion in MKL1 leads to hyperproliferation of B cells in triplets with Hodgkin lymphoma

Record J; Sendel A; Kritikos J; Kuznetsov NV; Brauner H; Nagy N; Griseti E; Andersson J; Claesson H-E; Winqvist O; Burns SO; Bjorkholm M; Westerberg LS
Review: IMMUNOLOGICAL REVIEWS. 2013;256(1):282-299

Actin cytoskeletal defects in immunodeficiency.

Moulding DA; Record J; Malinova D; Thrasher AJ

Employments

Postdoctoral Studies, Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, 2024-2025
Postdoctoral Researcher, Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, 2021-2024

About me

Selected publications

Articles

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