Jonas Söderholm

Publications
CV
Public outreach and news

Articles

Article: THERAPEUTIC ADVANCES IN INFECTIOUS DISEASE. 2021;8:20499361211053929
Hepatitis C outreach project and cross-sectional epidemiology in high-risk populations in Trondheim, Norway
Hannula R; Soderholm J; Svendsen T; Skaland M; Nordbo SA; Steinum H; Damas JK
Article: BMJ OPEN. 2020;10(9):e035996
Sick leave and disability pension in patients with chronic hepatitis C compared with a matched general population: a nationwide register study
Busch K; Hansson F; Holton M; Lagging M; Westin J; Kovamees J; Sallberg M; Soderholm J
Article: LIVER INTERNATIONAL. 2020;40(8):1832-1840
Frequent loss to follow-up after diagnosis of hepatitis C virus infection: A barrier towards the elimination of hepatitis C virus
Aleman S; Soderholm J; Busch K; Kovamees J; Duberg A-S
Article: SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY. 2020;55(5):574-580
High risk of non-alcoholic liver disease mortality in patients with chronic hepatitis C with illicit substance use disorder
Kaberg M; Larsson SB; Jerkeman A; Nystedt A; Duberg A-S; Kovamees J; Ydreborg M; Aleman S; Busch K; Blome MA; Weiland O; Soderholm J
Article: JOURNAL OF NEUROLOGY. 2019;266(9):2208-2215
Lower risk of multiple sclerosis in patients with chronic hepatitis C: a nationwide population-based registry study
Soderholm J; Yilmaz A; Svenningsson A; Busch K; Wejstal R; Brolund A; Kovamees J; Sallberg M; Lagging M; Gisslen M
Article: JOURNAL OF HEPATOLOGY. 2018;68(5):904-911
Higher risk of renal disease in chronic hepatitis C patients: Antiviral therapy survival benefit in patients on hemodialysis
Soderholm J; Millbourn C; Busch K; Kovamees J; Schvarcz R; Lindahl K; Bruchfeld A
Article: PLOS ONE. 2018;13(5):e0198296
Reduced ITPase activity and favorable IL28B genetic variant protect against ribavirin-induced anemia in interferon-free regimens
Vasanthakumar A; Davis JW; Abunimeh M; Soderholm J; Zha J; Dumas EO; Cohen DE; Waring JF; Lagging M
Article: SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY. 2017;52(1):61-68
Prevalence and comorbidities of chronic hepatitis C: a nationwide population-based register study in Sweden
Busch K; Waldenstrom J; Lagging M; Aleman S; Weiland O; Kovamees J; Duberg A-S; Soderholm J
Article: PLOS ONE. 2013;8(2):e56991
Impact of Soluble CD26 on Treatment Outcome and Hepatitis C Virus-Specific T Cells in Chronic Hepatitis C Virus Genotype 1 Infection
Soderholm J; Waldenstrom J; Askarieh G; Pilli M; Bochud P-Y; Negro F; Pawlotsky J-M; Zeuzem S; Ferrari C; Norkrans G; Wejstal R; Westin J; Neumann AU; Haagmans BL; Lindh M; Missale G; Hellstrand K; Lagging M
Article: VACCINE. 2012;30(48):6946-6954
Influenza A vaccines using linear expression cassettes delivered via electroporation afford full protection against challenge in a mouse model
Shen X; Soderholm J; Lin F; Kobinger G; Bello A; Gregg DA; Broderick KE; Sardesai NY
Article: JOURNAL OF GENERAL VIROLOGY. 2012;93(Pt 8):1680-1686
Limited effect on NS3-NS4A protein cleavage after alanine substitutions within the immunodominant HLA-A2-restricted epitope of the hepatitis C virus genotype 3a non-structural 3/4A protease
Ahlen G; Chen A; Roe B; Falkeborn T; Frelin L; Hall WW; Sallberg M; Soderholm J
Article: GUT. 2012;61(4):589-596
Hepatitis C virus non-structural 3/4A protein interferes with intrahepatic interferon-γ production
Brenndorfer ED; Brass A; Soderholm J; Frelin L; Aleman S; Bode JG; Sallberg M
Article: JOURNAL OF VIRAL HEPATITIS. 2011;18(7):e325-e331
IL28B polymorphisms determine early viral kinetics and treatment outcome in patients receiving peginterferon/ribavirin for chronic hepatitis C genotype 1
Lindh M; Lagging M; Arnholm B; Eilard A; Nilsson S; Norkrans G; Soderholm J; Wahlberg T; Wejstal R; Westin J; Hellstrand K
Article: JOURNAL OF IMMUNOLOGY. 2011;186(9):5107-5118
Heterologous T Cells Can Help Restore Function in Dysfunctional Hepatitis C Virus Nonstructural 3/4A-Specific T Cells during Therapeutic Vaccination
Chen A; Ahlen G; Brenndorfer ED; Brass A; Holmstrom F; Chen M; Soderholm J; Milich DR; Frelin L; Sallberg M
Article: GENE THERAPY. 2011;18(3):258-265
Prototype development and preclinical immunogenicity analysis of a novel minimally invasive electroporation device
Broderick KE; Shen X; Soderholm J; Lin F; McCoy J; Khan AS; Yan J; Morrow MP; Patel A; Kobinger GP; Kemmerrer S; Weiner DB; Sardesai NY
Article: PLOS ONE. 2011;6(2):e17232
Response Prediction in Chronic Hepatitis C by Assessment of IP-10 and IL28B-Related Single Nucleotide Polymorphisms
Lagging M; Askarieh G; Negro F; Bibert S; Soderholm J; Westin J; Lindh M; Romero A; Missale G; Ferrari C; Neumann AU; Pawlotsky J-M; Haagmans BL; Zeuzem S; Bochud P-Y; Hellstrand K
Article: JOURNAL OF VIROLOGY. 2011;85(3):1370-1383
Coexpressed RIG-I Agonist Enhances Humoral Immune Response to Influenza Virus DNA Vaccine
Luke JM; Simon GG; Soederholm J; Errett JS; August T; Gale MJ; Hodgson CP; Williams JA
Article: GENE THERAPY. 2010;17(6):811-814
Cutaneous vaccination using microneedles coated with hepatitis C DNA vaccine
Gill HS; Soderholm J; Prausnitz MR; Sallberg M
Article: HEPATOLOGY. 2010;51(5):1523-1530
Systemic and Intrahepatic Interferon-Gamma-Inducible Protein 10 kDa Predicts the First-Phase Decline in Hepatitis C Virus RNA and Overall Viral Response to Therapy in Chronic Hepatitis C
Askarieh G; Alsio A; Pugnale P; Negro F; Ferrari C; Neumann AU; Pawlotsky J-M; Schalm SW; Zeuzem S; Norkrans G; Westin J; Soderholm J; Hellstrand K; Lagging M
Article: JOURNAL OF IMMUNOLOGY. 2007;179(7):4741-4753
In vivo electroporation enhances the immunogenicity of hepatitis C virus nonstructural 3/4A DNA by increased local DNA uptake, protein expression, inflammation, and infiltration of CD3⁺ T cells
Ahlen G; Soderholm J; Tjelle T; Kjeken R; Frelin L; Hoglund U; Blomberg P; Fons M; Mathiesen I; Sallberg M
Article: JOURNAL OF INFECTIOUS DISEASES. 2006;194(12):1724-1728
A complete mutational fitness map of the hepatitis C virus nonstructural 3 protease:: Relation to recognition by cytotoxic T lymphocytes
Soderholm J; Sallberg M
Article: GUT. 2006;55(2):266-274
Relation between viral fitness and immune escape within the hepatitis C virus protease
Söderholm J; Ahlén G; Kaul A; Frelin L; Alheim M; Barnfield C; Liljeström P; Weiland O; Milich DR; Bartenschlager R; Sällberg M
Article: GENE THERAPY. 2003;10(8):686-699
Low dose and gene gun immunization with a hepatitis C virus nonstructural (NS) 3 DNA-based vaccine containing NS4A inhibit NS3/4A-expressing tumors in vivo
Frelin L; Alheim M; Chen A; Söderholm J; Rozell B; Barnfield C; Liljeström P; Sällberg M
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All other publications

Corrigendum: HEPATOLOGY. 2016;64(6):2278-2279
Poster Session II (Abstracts 730-1194) (vol 64, pg 361A, 2016)
Soderholm J; Millbourn C; Busch K; Kovamees J; Schvarcz R; Lindahl K; Bruchfeld A
Review: EXPERT REVIEW OF HEMATOLOGY. 2010;3(4):381-391
Immunotherapy with histamine dihydrochloride for the prevention of relapse in acute myeloid leukemia
Martner A; Thoren FB; Aurelius J; Soderholm J; Brune M; Hellstrand K
Thesis / dissertation: 2006
The hepatitis C virus and immune escape : relation between sequence variations and the in vitro and in vivo functionality of the non-structural 3/4A complex
Söderholm, Jonas

Employments

Affiliated to Teaching/Tutoring, Department of Laboratory Medicine, Karolinska Institutet, 2022-2025

Degrees and Education

Docent, Karolinska Institutet, 2021
Doctor Of Philosophy, Department of Laboratory Medicine, Karolinska Institutet, 2006

Articles

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Degrees and Education

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