John Wahren

Publications
CV
Public outreach and news

Articles

Article: DIABETES CARE. 2016;39(4):596-602
Long-Acting C-Peptide and Neuropathy in Type 1 Diabetes: A 12-Month Clinical Trial
Wahren J; Foyt H; Daniels M; Arezzo JC
Article: DIABETES, OBESITY AND METABOLISM. 2015;17(8):781-788
Efficacy of a long-acting C-peptide analogue against peripheral neuropathy in streptozotocin-diabetic mice
Jolivalt CG; Rodriguez M; Wahren J; Calcutt NA
Article: DIABETOLOGE. 2013;9(4):319-331
C-peptide • Novel therapeutic approach to microvascular complications of type 1 diabetes?
Wahren J; Kallas A
Article: DIABETES. 2012;61(4):761-772
The Clinical Potential of C-Peptide Replacement in Type 1 Diabetes
Wahren J; Kallas A; Sima AAF
Article: PLOS ONE. 2011;6(12):e28294
C-Peptide Increases Na,K-ATPase Expression via PKC- and MAP Kinase-Dependent Activation of Transcription Factor ZEB in Human Renal Tubular Cells
Galuska D; Pirkmajer S; Barres R; Ekberg K; Wahren J; Chibalin AV
Article: GASTROENTEROLOGY. 2010;139(6):1961-1971.e1
Splanchnic Balance of Free Fatty Acids, Endocannabinoids, and Lipids in Subjects With Nonalcoholic Fatty Liver Disease
Westerbacka J; Kotronen A; Fielding BA; Wahren J; Hodson L; Perttila J; Seppanen-Laakso T; Suortti T; Arola J; Hultcrantz R; Castillo S; Olkkonen VM; Frayn KN; Oresic M; Yki-Jarvinen H
Article: REVIEW OF DIABETIC STUDIES. 2009;6(3):223-224
C-Peptide is Relevant in Type 1 Diabetes and its Complications: Summary and Conclusions to the Special Issue.
Wahren J; Sima AAF
Article: REVIEW OF DIABETIC STUDIES. 2009;6(3):203-210
C-Peptide: the missing link in diabetic nephropathy?
Nordquist L; Wahren J
Article: REVIEW OF DIABETIC STUDIES. 2009;6(3):136-137
The relevance of C-Peptide in diabetes and its complications: an introduction to the special issue.
Sima AAF; Wahren J
Article: SCANDINAVIAN JOURNAL OF CLINICAL AND LABORATORY INVESTIGATION. 2009;69(8):837-842
Precise determination of glucose-d₂/glucose ratio in human serum and plasma by APCI LC-MS/MS
Ullah S; Wahren J; Beck O
Article: EXPERIMENTAL DIABETES RESEARCH. 2008;2008:730594
C-Peptide and Its C-Terminal Fragments Improve Erythrocyte Deformability in Type 1 Diabetes Patients
Hach T; Forst T; Kunt T; Ekberg K; Pfuetzner A; Wahren J
Article: JOURNAL OF CHROMATOGRAPHY B: ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES. 2007;856(1-2):15-19
Novel LC-MS/MS method for assay of 7α-hydroxy-4-cholesten-3-one in human plasma evidence for a significant extrahepatic metabolism
Lovgren-Sandblom A; Heverin M; Larsson H; Lundstrom E; Wahren J; Diczfalusy U; Bjorkhem I
Article: JOURNAL OF LIPID RESEARCH. 2007;48(4):944-951
Novel route for elimination of brain oxysterols across the blood-brain barrier:: conversion into 7α-hydroxy-3-oxo-4-cholestenoic acid
Meaney S; Heverin M; Panzenboeck U; Ekstrom L; Axelsson M; Andersson U; Diczfalusy U; Pikuleva I; Wahren J; Sattler W; Bjorkhem I
Article: DIABETOLOGIA. 2007;50(3):503-509
C-peptide is a bioactive peptide
Wahren J; Ekberg K; Jornvall H
Article: CELLULAR AND MOLECULAR LIFE SCIENCES. 2007;64(4):479-486
Cellular internalization of proinsulin C-peptide
Lindahl E; Nyman U; Melles E; Sigmundsson K; Stahlberg M; Wahren J; Obrink B; Shafqat J; Joseph B; Jornvall H
Article: DIABETES CARE. 2007;30(1):71-76
C-peptide replacement therapy and sensory nerve function in type 1 diabetic neuropathy
Ekberg K; Brismar T; Johansson B-L; Lindstrom P; Juntti-Berggren L; Norbhy A; Berne C; Arnqvist HJ; Bolinder J; Wahren J
Article: DIABETES/METABOLISM RESEARCH AND REVIEWS. 2007;23(1):63-70
C-peptide improves neuropathy in type 1 diabetic BB/Wor-rats
Zhang W; Kamiya H; Ekberg K; Wahren J; Sima AAF
Article: DIABETES. 2006;55(12):3581-3587
C-peptide reverses nociceptive neuropathy in type 1 diabetes
Kamiya H; Zhang W; Ekberg K; Wahren J; Sima AAF
Article: CELLULAR AND MOLECULAR LIFE SCIENCES. 2006;63(15):1805-1811
Proinsulin C-peptide elicits disaggregation of insulin resulting in enhanced physiological insulin effects
Shafqat J; Melles E; Sigmundsson K; Johansson B-L; Ekberg K; Alvelius G; Henriksson M; Johansson J; Wahren J; Jornvall H
Article: DIABETES/METABOLISM RESEARCH AND REVIEWS. 2006;22(4):313-322
Influence of C-peptide on early glomerular changes in diabetic mice
Maezawa Y; Yokote K; Sonezaki K; Fujimoto M; Kobayashi K; Kawamura H; Tokuyama T; Takemoto M; Ueda S; Kuwaki T; Mori S; Wahren J; Saito Y
Article: JOURNAL OF BIOMOLECULAR TECHNIQUES. 2005;16(4):392-397
Large-surface biosensor technology for enhanced recovery in protein characterization.
Melles E; Bergman T; Ståhlberg M; Thirstrup C; Wahren J; Jörnvall H; Shafqat J
Article: CELLULAR AND MOLECULAR LIFE SCIENCES. 2005;62(15):1772-1778
Separate functional features of proinsulin C-peptide
Henriksson M; Nordling E; Melles E; Shafqat J; Ståhlberg M; Ekberg K; Persson B; Bergman T; Wahren J; Johansson J; Jörnvall H
Article: DIABETES CARE. 2005;28(6):1495-1497
Early microvascular dysfunction in healthy normal-weight males with heredity for type 2 diabetes
Jörneskog G; Kalani M; Kuhl J; Båvenholm P; Katz A; Allerstrand G; Alvarsson M; Efendic S; Östenson CG; Pernow J; Wahren J; Brismar K
Article: JOURNAL OF LIPID RESEARCH. 2005;46(5):1047-1052
Crossing the barrier:: net flux of 27-hydroxycholesterol into the human brain
Heverin M; Meaney S; Lütjohann D; Diczfalusy U; Wahren J; Björkhem I
Article: DIABETES. 2005;54(5):1364-1370
The contribution of visceral adipose tissue to splanchnic cortisol production in healthy humans
Andrew R; Westerbacka J; Wahren J; Yki-Järvinen H; Walker BR
Article: NEPHROLOGY DIALYSIS TRANSPLANTATION. 2005;20(3):532-538
C-peptide prevents glomerular hypertrophy and mesangial matrix expansion in diabetic rats
Samnegard B; Jacobson SH; Jaremko G; Johansson BL; Ekberg K; Isaksson B; Eriksson L; Wahren J; Sjöquist M
Article: DIABETOLOGIA. 2005;48(1):187-197
C-peptide stimulates ERK1/2 and JNK MAP kinases via activation of protein kinase C in human renal tubular cells
Zhong Z; Davidescu A; Ehrén I; Ekberg K; Jörnvall H; Wahren J; Chibalin AV
Article: CELLULAR AND MOLECULAR LIFE SCIENCES. 2004;61(23):2979-2982
Degradation of proinsulin C-peptide in kidney and placenta extracts by a specific endoprotease activity
Melles E; Jörnvall H; Tryggvason S; Danielsson KG; Ekberg K; Tryggvason K; Wahren J; Bergman T
Article: CELLULAR AND MOLECULAR LIFE SCIENCES. 2004;61(21):2782-2790
C-peptide stimulates Na⁺, K⁺-ATPase via activation of ERK1/2 MAP kinases in human renal tubular cells
Zhong Z; Kotova O; Davidescu A; Ehrén I; Ekberg K; Jörnvall H; Wahren J; Chibalin AV
Article: NEPHROLOGY DIALYSIS TRANSPLANTATION. 2004;19(6):1385-1391
C-peptide and captopril are equally effective in lowering glomerular hyperfiltration in diabetic rats
Samnegård B; Jacobson SH; Johansson BL; Ekberg K; Isaksson B; Wahren J; Sjöquist M
Article: CELLULAR AND MOLECULAR LIFE SCIENCES. 2004;61(6):727-732
C-peptide fragments stimulate glucose utilization in diabetic rats
Sato Y; Oshida Y; Han YQ; Morishita Y; Li L; Ekberg K; Jörnvall H; Wahren J
Article: EXPERIMENTAL DIABESITY RESEARCH. 2004;5(1):15-23
Molecular and cellular effects of C-peptide -: New perspectives on an old peptide
Wahren J; Shafqat JV; Johansson J; Chibalin A; Ekberg K; Jörnvall H
Article: AMERICAN JOURNAL OF PHYSIOLOGY - ENDOCRINOLOGY AND METABOLISM. 2004;286(1):E14-E19
C-peptide improves adenosine-induced myocardial vasodilation in type 1 diabetes patients
Johansson BL; Sundell J; Ekberg K; Jonsson C; Seppänen M; Raitakari O; Luotolahti M; Nuutila P; Wahren J; Knuuti J
Article: JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM (JCEM). 2003;88(10):4559-4564
Direct measurements of the permeability surface area for insulin and glucose in human skeletal muscle
Gudbjörnsdóttir S; Sjöstrand M; Strindberg L; Wahren J; Lönnroth P
Article: AMERICAN JOURNAL OF PHYSIOLOGY - ENDOCRINOLOGY AND METABOLISM. 2003;285(4):E864-E870
C-peptide increases forearm blood flow in patients with type 1 diabetes via a nitric oxide-dependent mechanism
Johansson BL; Wahren J; Pernow J
Article: DIABETES. 2003;52(7):1812-1817
Effects of proinsulin C-peptide in experimental diabetic neuropathy - Vascular actions and modulation by nitric oxide synthase inhibition
Cotter MA; Ekberg K; Wahren J; Cameron NE
Article: CELLULAR AND MOLECULAR LIFE SCIENCES. 2003;60(5):1019-1025
Proinsulin C-peptide and its C-terminal pentapeptide:: degradation in human serum and Schiff base formation with subsequent CO₂ incorporation
Melles E; Bergman T; Alvelius G; Jonsson A; Ekberg K; Wahren J; Jörnvall H
Article: DIABETES. 2003;52(2):536-541
Amelioration of sensory nerve dysfunction by C-peptide in patients with type 1 diabetes
Ekberg K; Brismar T; Johansson BL; Jonsson B; Lindström P; Wahren J
Article: DIABETES. 2002;51(10):3077-3082
C-peptide exerts beneficial effects on myocardial blood flow and function in patients with type 1 diabetes
Hansen A; Johansson BL; Wahren J; von Bibra H
Article: LIFE SCIENCES. 2002;71(12):1361-1370
In vivo biodistribution and pharmacokinetics of ¹⁸F-labeled human C-peptide:: evaluation in monkeys using positron emission tomography
Fredriksson A; Ekberg K; Ingvar M; Johansson BL; Wahren J; Stone-Elander S
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2002;295(5):1035-1040
Molecular effects of proinsulin C-peptide
Johansson J; Ekberg K; Shafqat J; Henriksson M; Chibalin A; Wahren J; Jörnvall H
Article: CELLULAR AND MOLECULAR LIFE SCIENCES. 2002;59(7):1185-1189
Proinsulin C-peptide and its analogues induce intracellular Ca²⁺ increases in human renal tubular cells
Shafqat J; Juntti-Berggren L; Zhong Z; Ekberg K; Köhler M; Berggren PO; Johansson J; Wahren J; Jörnvall H
Article: JOURNAL OF CARDIOTHORACIC AND VASCULAR ANESTHESIA. 2002;16(3):308-315
Splanchnic blood flow and oxygen uptake during cardiopulmonary bypass
Gårdebäck M; Settergren G; Brodin L; Jorfeldt L; Galuska D; Ekberg K; Wahren J
Article: DIABETOLOGIA. 2001;44(9):1184-1188
Insulin binding monitored by fluorescence correlation spectroscopy
Zhong ZH; Pramanik A; Ekberg K; Jansson OT; Jörnvall H; Wahren J; Rigler R
Article: DIABETOLOGIA. 2001;44(7):889-897
C-peptide prevents and improves chronic Type I diabetic polyneuropathy in the BB/Wor rat
Sima AAF; Zhang W; Sugimoto K; Henry D; Li Z; Wahren J; Grunberger G
Article: CLINICAL SCIENCE. 2001;101(1):59-64
Diminished skin blood flow in Type I diabetes: evidence for non-endothelium-dependent dysfunction
Katz A; Ekberg K; Johansson BL; Wahren J
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2001;284(1):94-98
C-peptide binding to human cell membranes:: Importance of Glu27
Pramanik A; Ekberg K; Zhong Z; Shafqat J; Henriksson M; Jansson O; Tibell A; Tally M; Wahren J; Jörnvall H; Rigler R; Johnansson J
Article: JOURNAL OF LABELLED COMPOUNDS AND RADIOPHARMACEUTICALS. 2001;44(7):509-519
Labeling of human C-peptide by conjugation with N-succinimidyl-4-[¹⁸F]fluorobenzoate
Fredriksson A; Johnström P; Stone-Elander S; Jonasson P; Nygren P; Ekberg K; Johansson BL; Wahren J
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2001;280(2):423-427
Specific binding of proinsulin C-peptide to intact and to detergent-solubilized human skin fibroblasts
Henriksson M; Pramanik A; Shafqat J; Zhong ZH; Tally M; Ekberg K; Wahren J; Rigler R; Johansson J; Jornvall H
Article: DIABETIC MEDICINE. 2000;17(3):181-189
Beneficial effects of C-peptide on incipient nephropathy and neuropathy in patients with Type 1 diabetes mellitus
Johansson BL; Borg K; Fernqvist-Forbes E; Kernell A; Odergren T; Wahren J
Article: CLINICAL SCIENCE. 2000;98(3):283-290
Effects of proinsulin C-peptide on nitric oxide, microvascular blood flow and erythrocyte Na⁺,K⁺-ATPase activity in diabetes mellitus type I
Forst T; De la Tour DD; Kunt T; Pfützner A; Goitom K; Pohlmann T; Schneider S; Johansson BL; Wahren J; Löbig M; Engelbach M; Beyer J; Vague P
Article: CELLULAR AND MOLECULAR LIFE SCIENCES. 2000;57(2):337-342
Unordered structure of proinsulin C-peptide in aqueous solution and in the presence of lipid vesicles
Henriksson M; Shafqat J; Liepinsh E; Tally M; Wahren J; Jörnvall H; Johansson J
Article: JOURNAL OF BIOTECHNOLOGY. 2000;76(2-3):215-226
Integrated bioprocess for production of human proinsulin C-peptide via heat release of an intracellular heptameric fusion protein
Jonasson P; Nygren P; Jörnvall H; Johansson BL; Wahren J; Uhlén M; Ståhl S
Article: EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY. 2000;55(10):737-741
Site of nicotine absorption from a vapour inhaler - comparison with cigarette smoking
Lunell E; Molander L; Ekberg K; Wahren J
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 1999;96(23):13318-13323
Specific binding of proinsulin C-peptide to human cell membranes
Rigler R; Pramanik A; Jonasson P; Kratz G; Jansson OT; Nygren P; Ståhl S; Ekberg K; Johansson BL; Uhlén S; Uhlén M; Jörnvall H; Wahren J
Article: AMERICAN JOURNAL OF PHYSIOLOGY. 1999;277(4):E717-E723
Origins of the hydrogen bound to carbon 1 of glucose in fasting: significance in gluconeogenesis quantitation.
Chandramouli V; Ekberg K; Schumann WC; Wahren J; Landau BR
Article: AMERICAN JOURNAL OF PHYSIOLOGY. 1999;277(2):E238-E244
Arterial KIC as marker of liver and muscle intracellular leucine pools in healthy and type 1 diabetic humans.
Barazzoni R; Meek SE; Ekberg K; Wahren J; Nair KS
Article: DIABETOLOGIA. 1999;42(8):958-964
Rat C peptide I and II stimulate glucose utilization in STZ-induced diabetic rats
Li L; Oshida Y; Kusunoki M; Yamanouchi K; Johansson BL; Wahren J; Sato Y
Article: DIABETOLOGIA. 1999;42(7):812-818
Brain substrate utilisation during acute hypoglycaemia
Wahren J; Ekberg K; Fernqvist-Forbes E; Nair S
Article: DIABETES. 1999;48(2):292-298
Contributions by kidney and liver to glucose production in the postabsorptive state and after 60 h of fasting
Ekberg K; Landau BR; Wajngot A; Chandramouli V; Efendic S; Brunengraber H; Wahren J
Article: JOURNAL OF LIPID RESEARCH. 1998;39(8):1594-1600
Cholesterol homeostasis in human brain:: turnover of 24S-hydroxycholesterol and evidence for a cerebral origin of most of this oxysterol in the circulation
Björkhem I; Lütjohann D; Diczfalusy U; Ståhle L; Ahlborg G; Wahren J
Article: AMERICAN JOURNAL OF PHYSIOLOGY. 1998;274(5):E954-E961
Limitations in estimating gluconeogenesis and Cori cycling from mass isotopomer distributions using [U-¹³C₆]glucose
Landau BR; Wahren J; Ekberg K; Previs SF; Yang DW; Brunengraber H
Article: GENE. 1998;210(2):203-210
Gene fragment polymerization gives increased yields of recombinant human proinsulin C-peptide
Jonasson P; Nygren P; Johansson BL; Wahren J; Uhlén M; Ståhl S
Article: PSYCHOPHARMACOLOGY. 1998;136(2):179-189
Cerebral effects of nicotine during cognition in smokers and non-smokers
Ghatan PH; Ingvar M; Eriksson L; Stone-Elander S; Serrander M; Ekberg K; Wahren J
Article: DIABETOLOGIA. 1998;41(3):287-291
Differential effects of proinsulin C-peptide fragments on Na⁺, K⁺-ATPase activity of renal tubule segments
Ohtomo Y; Bergman T; Johansson BL; Jörnvall H; Wahren J
Article: EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY AND DIABETES. 1998;106(4):270-276
New aspects on biological activity of C-peptide in IDDM patients
Forst T; Kunt T; Pfützner A; Beyer J; Wahren J
Article: HORMONE AND METABOLIC RESEARCH. 1998;30(1):A2-A5
New aspects of C-peptide physiology
Wahren J; Johansson BL
Article: AMERICAN JOURNAL OF PHYSIOLOGY. 1997;273(6):e1209-e1215
Quantifying gluconeogenesis during fasting
Chandramouli V; Ekberg K; Schumann WC; Kalhan SC; Wahren J; Landau BR
Article: ATHEROSCLEROSIS. 1997;132(1):95-103
Smokeless tobacco use and atherosclerosis: An ultrasonographic investigation of carotid intima media thickness in healthy middle-aged men
Bolinder G; Noren A; deFaire U; Wahren J
Article: AMERICAN JOURNAL OF PHYSIOLOGY. 1997;272(6):E1059-E1064
Glucose production and gluconeogenesis in adults with uncomplicated falciparum malaria
Dekker E; Romijn JA; Ekberg K; Wahren J; VanThien H; Ackermans MT; Thuy LTD; Chandramouli V; Kager PA; Landau BR; Sauerwein HP
Article: EUROPEAN JOURNAL OF CLINICAL INVESTIGATION. 1997;27(5):427-433
Long-term use of smokeless tobacco and physical performance in middle-aged men
Bolinder G; Noren A; Wahren J; DeFaire U
Article: AMERICAN JOURNAL OF PHYSIOLOGY. 1997;272(4):E678-E687
Whole body and splanchnic metabolic and circulatory effects of glucose during beta-adrenergic receptor inhibition
Brundin T; Aksnes AK; Wahren J
Article: DIABETES AND METABOLISM. 1997;23(2):149-154
Effect of C-peptide on insulin and glucagon release by isolated perfused rat pancreas
LeclercqMeyer V; Malaisse WJ; Johansson BL; Wahren J
Article: AMERICAN JOURNAL OF PHYSIOLOGY. 1996;271(6):E1110-E1117
Glycerol production and utilization in humans: Sites and quantitation
Landau BR; Wahren J; Previs SF; Ekberg K; Chandramouli V; Brunengraber H
Article: JOURNAL OF INTERNAL MEDICINE. 1996;240(3):115-124
C-peptide revisited - New physiological effects and therapeutic implications
Wahren J; Johansson BL; WallbergHenriksson H; Linde B; FernqvistForbes E; Zierath JR
Article: AMERICAN JOURNAL OF PHYSIOLOGY. 1996;271(3):E496-E504
Effects of oral vs iv glucose administration on splanchnic and extrasplanchnic O-2 uptake and blood flow
Brundin T; Branstrom R; Wahren J
Article: JOURNAL OF CLINICAL INVESTIGATION. 1996;98(2):378-385
Contributions of gluconeogenesis to glucose production in the fasted state
Landau BR; Wahren J; Chandramouli V; Schumann WC; Ekberg K; Kalhan SC
Article: ACTA PHYSIOLOGICA. 1996;157(2):253-258
Effect of C-peptide administration on whole body glucose utilization in STZ-induced diabetic rats
Wu W; Oshida Y; Yang WP; Li L; Ohsawa I; Sato J; Iwao S; Johansson BL; Wahren J; Sato Y
Article: DIABETOLOGIA. 1996;39(6):687-695
C-peptide improves autonomic nerve function in IDDM patients
Johansson BL; Borg K; FernqvistForbes E; Odergren T; Remahl S; Wahren J
Article: DIABETOLOGIA. 1996;39(2):199-205
C-peptide stimulates rat renal tubular Na+, K+-ATPase activity in synergism with neuropeptide Y
Ohtomo Y; Aperia A; Sahlgren B; Johansson BL; Wahren J
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 1995;270(37):21715-21717
GLUCONEOGENESIS AND GLUCURONIDATION IN LIVER IN-VIVO AND THE HETEROGENEITY OF HEPATOCYTE FUNCTION
EKBERG K; CHANDRAMOULI V; KUMARAN K; SCHUMANN WC; WAHREN J; LANDAU BR
Article: AMERICAN JOURNAL OF PHYSIOLOGY. 1995;269(3):E583-E590
SPLANCHNIC AND MUSCLE METABOLISM DURING EXERCISE IN NIDDM PATIENTS
MARTIN IK; KATZ A; WAHREN J
Article: AMERICAN JOURNAL OF PHYSIOLOGY. 1995;269(1):E18-E26
A LIMITATION IN THE USE OF MASS ISOTOPOMER DISTRIBUTIONS TO MEASURE GLUCONEOGENESIS IN FASTING HUMANS
LANDAU BR; FERNANDEZ CA; PREVIS SF; EKBERG K; CHANDRAMOULI V; WAHREN J; KALHAN SC; BRUNENGRABER H
Article: DIABETOLOGIA. 1995;38(7):831-838
ESTIMATES OF KREBS CYCLE ACTIVITY AND CONTRIBUTIONS OF GLUCONEOGENESIS TO HEPATIC GLUCOSE-PRODUCTION IN FASTING HEALTHY-SUBJECTS AND IDDM PATIENTS
LANDAU BR; CHANDRAMOULI V; SCHUMANN WC; EKBERG K; KUMARAN K; KALHAN SC; WAHREN J
Article: CLINICAL PHYSIOLOGY AND FUNCTIONAL IMAGING. 1995;15(4):377-396
METABOLIC, THERMAL AND CIRCULATORY EFFECTS OF INTRAVENOUS-INFUSION OF AMINO-ACIDS IN TETRAPLEGIC PATIENTS
AKSNES AK; BRUNDIN T; HJELTNES N; WAHREN J
Article: JOURNAL OF CLINICAL INVESTIGATION. 1995;95(6):2926-2937
PROTEIN DYNAMICS IN WHOLE-BODY AND IN SPLANCHNIC AND LEG TISSUES IN TYPE-I DIABETIC-PATIENTS
NAIR KS; FORD GC; EKBERG K; FERNQVISTFORBES E; WAHREN J
Article: JOURNAL OF CLINICAL INVESTIGATION. 1995;95(1):172-178
USE OF (H2O)-H-2 FOR ESTIMATING RATES OF GLUCONEOGENESIS - APPLICATION TO THE FASTED STATE
LANDAU BR; WAHREN J; CHANDRAMOULI V; SCHUMANN WC; EKBERG K; KALHAN SC
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All other publications

Editorial comment: JOURNAL OF INTERNAL MEDICINE. 2017;281(1):3-6
C-peptide and the pathophysiology of microvascular complications of diabetes
Wahren J
Review: DIABETES RESEARCH AND CLINICAL PRACTICE. 2015;107(3):309-319
C-peptide: New findings and therapeutic possibilities
Wahren J; Larsson C
Review: AMERICAN JOURNAL OF PHYSIOLOGY - ENDOCRINOLOGY AND METABOLISM. 2014;307(11):E955-E968
Physiological effects and therapeutic potential of proinsulin C-peptide
Yosten GLC; Maric-Bilkan C; Luppi P; Wahren J
Review: BIOMOLECULAR CONCEPTS. 2014;5(2):109-118
The structure, molecular interactions and bioactivities of proinsulin C-peptide correlate with a tripartite molecule.
Landreh M; Johansson J; Wahren J; Jörnvall H
Published conference paper: DIABETES/METABOLISM RESEARCH AND REVIEWS. 2014;30(2):124-131
Enhanced insulin action following subcutaneous co-administration of insulin and C-peptide in rats
Kubota M; Sato Y; Khookhor O; Ekberg K; Chibalin AV; Wahren J
Review: DIABETES/METABOLISM RESEARCH AND REVIEWS. 2013;29(5):357-362
Can C-peptide mediated anti-inflammatory effects retard the development of microvascular complications of type 1 diabetes?
Luppi P; Kallas A; Wahren J
Editorial comment: DIABETES. 2012;61(9):2228-2229
Loss of Pulsatile Insulin Secretion: A Factor in the Pathogenesis of Type 2 Diabetes?
Wahren J; Kallas A
Review: PEDIATRIC DIABETES. 2011;12(3):276-292
C-peptide and long-term complications of diabetes
Luppi P; Cifarelli V; Wahren J
Editorial comment: EXPERIMENTAL DIABETES RESEARCH. 2008;2008:384219
New Tricks by an Old Dog
Forst T; Wahren J
Review: ANNUAL REVIEW OF NUTRITION. 2007;27:329-345
Splanchnic regulation of glucose production
Wahren J; Ekberg K
Review: CLINICAL PHYSIOLOGY AND FUNCTIONAL IMAGING. 2004;24(4):180-189
C-peptide: new findings and therapeutic implications in diabetes
Wahren J
Editorial comment: DIABETES/METABOLISM RESEARCH AND REVIEWS. 2003;19(5):345-347
C-peptide makes a comeback
Wahren J; Jörnvall H
Letter: LAKARTIDNINGEN. 2002;99(26-27):2974
[Actions of the tobacco industry and Swedish physicians].
Wahren J
Review: CURRENT DIABETES REPORTS. 2001;1(3):261-266
C-peptide: a new potential in the treatment of diabetic nephropathy.
Wahren J; Ekberg K; Samnegård B; Johansson BL
Editorial comment: CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE. 2001;4(4):253-254
Carbohydrates
Wahren J; Leverve X
Review: INTERNATIONAL JOURNAL OF EXPERIMENTAL DIABETES RESEARCH. 2001;2(2):145-151
Proinsulin C-peptide--a consensus statement.
Sima AA; Grunberger G; Jörnvall H; Wahren J; C-peptide Study Group
Review: JOURNAL OF INTERNAL MEDICINE. 2001;249(1):27-40
Substance P:: a pioneer amongst neuropeptides
Hökfelt T; Pernow B; Wahren J
Review: AMERICAN JOURNAL OF PHYSIOLOGY - ENDOCRINOLOGY AND METABOLISM. 2000;278(5):E759-E768
Role of C-peptide in human physiology
Wahren J; Ekberg K; Johansson J; Henriksson M; Pramanik A; Johansson BL; Rigler R; Jörnvall H
Review: JOURNEES ANNUELLES DE DIABETOLOGIE DE L'HOTEL-DIEU. 1999;:231-241
[C-peptide, new discoveries and therapeutic implications].
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Letter: BRITISH JOURNAL OF ANAESTHESIA. 1997;78(3):339
Effect of amino acid infusion on body temperature during anaesthesia
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Professor Emeritus/Emerita, Department of Molecular Medicine and Surgery, Karolinska Institutet, 2024-2026

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Docent, Karolinska Institutet, 1966

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