Jiangning Yang

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Public outreach and news

Articles

Journal article: EUROPEAN HEART JOURNAL. 2023;44:ehad655.3099
Paracrine cardioprotective signaling by red blood cells through hypoxia-mediated activation of soluble guanylate cyclase and release of cyclic guanosine monophosphate
Yang JN; Sundqvist M; Zheng X; Jiao T; Collado A; Mahdi A; Tengbom J; Mergia E; Zhou Z; Carlstrom M; Akaike T; Cortese-Krott M; Weitzberg E; Lundberg JO; Pernow J
Journal article: EUROPEAN HEART JOURNAL. 2023;44:ehad655.3066
Erythrocyte-derived extracellular vesicles from type 2 diabetes patients induce endothelial dysfunction through arginase 1
Collado A; Humoud R; Eldh M; Jiao T; Domingo E; Kontidou E; Yang J; Mahdi A; Gabrielsson S; Eriksson P; Zhou Z; Pernow J
Journal article: EUROPEAN HEART JOURNAL. 2023;44:ehad655.3096
Stimulation of soluble guanylyl cyclase in erythrocytes induces export of cGMP and cardioprotection in type 2 diabetes
Jiao T; Collado A; Mahdi A; Tengbom J; Tratsiakovich Y; Milne G; Alvarsson M; Lundberg J; Zhou Z; Yang J; Pernow J
Article: JOURNAL OF CLINICAL INVESTIGATION. 2023;133(17):e167693
Hypoxic erythrocytes mediate cardioprotection through activation of soluble guanylate cyclase and release of cyclic GMP
Yang J; Sundqvist ML; Zheng X; Jiao T; Collado A; Tratsiakovich Y; Mahdi A; Tengbom J; Mergia E; Catrina S-B; Zhou Z; Carlstroem M; Akaike T; Cortese-Krott MM; Weitzberg E; Lundberg JO; Pernow J
Article: JACC: BASIC TO TRANSLATIONAL SCIENCE. 2023;8(8):907-918
Stimulation of Erythrocyte Soluble Guanylyl Cyclase Induces cGMP Export and Cardioprotection in Type 2 Diabetes
Jiao T; Collado A; Mahdi A; Tengbom J; Tratsiakovich Y; Milne GT; Alvarsson M; Lundberg JO; Zhou Z; Yang J; Pernow J
Article: JOURNAL OF INTERNAL MEDICINE. 2023;293(2):228-245
The red blood cell as a mediator of endothelial dysfunction in patients with familial hypercholesterolemia and dyslipidemia
Mahdi A; Wodaje T; Kovamees O; Tengbom J; Zhao A; Jiao T; Henricsson M; Yang J; Zhou Z; Nieminen AI; Levin M; Collado A; Brinck J; Pernow J
Article: BASIC RESEARCH IN CARDIOLOGY. 2022;117(1):46
Erythrocytes from patients with ST-elevation myocardial infarction induce cardioprotection through the purinergic P2Y₁₃ receptor and nitric oxide signaling
Jiao T; Collado A; Mahdi A; Jurga J; Tengbom J; Saleh N; Verouhis D; Bohm F; Zhou Z; Yang J; Pernow J
Article: JACC: BASIC TO TRANSLATIONAL SCIENCE. 2022;7(3):193-204
Erythrocytes Induce Vascular Dysfunction in COVID-19
Mahdi A; Collado A; Tengbom J; Jiao T; Wodaje T; Johansson N; Farnebo F; Farnert A; Yang J; Lundberg JO; Zhou Z; Pernow J
Article: DIABETES. 2022;71(2):285-297
Downregulation of Erythrocyte miR-210 Induces Endothelial Dysfunction in Type 2 Diabetes
Zhou Z; Collado A; Sun C; Tratsiakovich Y; Mahdi A; Winter H; Chernogubova E; Seime T; Narayanan S; Jiao T; Jin H; Alvarsson M; Zheng X; Yang J; Hedin U; Catrina S-B; Maegdefessel L; Pernow J
Article: PHARMACOLOGY. 2022;107(3-4):160-166
Therapeutic Potential of Sunitinib in Ameliorating Endothelial Dysfunction in Type 2 Diabetic Rats
Mahdi A; Jiao T; Tratsiakovich Y; Wernly B; Yang J; Ostenson C-G; Danser AHJ; Pernow J; Zhou Z
Journal article: EUROPEAN HEART JOURNAL. 2021;42(Supplement_1):ehab724.3364
Erythrocytes induce vascular dysfunction in COVID-19
Mahdi A; Collado A; Tengbom J; Jiao T; Wodaje T; Yang J; Lundberg JO; Zhou Z; Pernow J
Article: ANTIOXIDANTS. 2021;10(7):1070
Dehydro-Tocotrienol-β Counteracts Oxidative-Stress-Induced Diabetes Complications in db/db Mice
Dallner G; Bentinger M; Hussain S; Sinha I; Yang J; Schwank-Xu C; Zheng X; Swiezewska E; Brismar K; Valladolid-Acebes I; Tekle M
Article: MICROORGANISMS. 2021;9(6):1137
Human Cytomegalovirus Reduces Endothelin-1 Expression in Both Endothelial and Vascular Smooth Muscle Cells
Yaiw K-C; Mohammad A-A; Taher C; Cui HL; Costa H; Kostopoulou ON; Jung M; Assinger A; Wilhelmi V; Yang J; Straat K; Rahbar A; Pernow J; Soderberg-Naucler C
Article: ATHEROSCLEROSIS. 2020;292:215-223
Endothelin-1 increases expression and activity of arginase 2 via ETB receptors and is co-expressed with arginase 2 in human atherosclerotic plaques
Rafnsson A; Matic LP; Lengquist M; Mahdi A; Shemyakin A; Paulsson-Berne G; Hansson GK; Gabrielsen A; Hedin U; Yang J; Pernow J
Article: FRONTIERS IN PHARMACOLOGY. 2020;11:603226
Erythrocytes Induce Endothelial Injury in Type 2 Diabetes Through Alteration of Vascular Purinergic Signaling
Mahdi A; Tratsiakovich Y; Tengbom J; Jiao T; Garib L; Alvarsson M; Yang J; Pernow J; Zhou Z
Journal article: EUROPEAN HEART JOURNAL. 2019;40(Supplement_1):ehz748.0351
P1592A cardioprotective effect of dietary nitrate mediated by red blood cells
Jiao T; Yang JN; Sundqvist M; Tratsiakovich Y; Hellenius ML; Weitzberg E; Lundberg J; Pernow J
Journal article: EUROPEAN HEART JOURNAL. 2019;40(Supplement_1):ehz746.0897
P6299Dietary nitrate restores cardiac ischemic tolerance in type 2 diabetic mice and protects against ischemia-reperfusion injury via soluble guanylate cyclase in red blood cells
Yang JN; Jiao T; Tratsiakovich Y; Mahdi A; Zhou Z; Lundberg JO; Pernow J
Article: CIRCULATION. 2019;139(23):2654-2663
Hemoglobin β93 Cysteine Is Not Required for Export of Nitric Oxide Bioactivity From the Red Blood Cell
Sun C-W; Yang J; Kleschyov AL; Zhuge Z; Carlstrom M; Pernow J; Wajih N; Isbell TS; Oh J-Y; Cabrales P; Tsai AG; Townes T; Kim-Shapiro DB; Patel RP; Lundberg JO
Journal article: THE FASEB JOURNAL. 2019;33:512.4
Sunitinib Improves Endothelial Function in Type 2 Diabetic Rats
Zhou Z; Mahdi A; Tratsiakovich Y; Jiao T; Yang J; Ostenson C-G; Danser AHJ; Pernow J
Article: FRONTIERS IN PHARMACOLOGY. 2019;10:861
The Effect of Glycemic Control on Endothelial and Cardiac Dysfunction Induced by Red Blood Cells in Type 2 Diabetes
Mahdi A; Jiao T; Yang J; Kovamees O; Alvarsson M; von Heijne M; Zhou Z; Pernow J
Article: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2018;19(12):E3942-3942
Altered Purinergic Receptor Sensitivity in Type 2 Diabetes-Associated Endothelial Dysfunction and Up₄A-Mediated Vascular Contraction
Mahdi A; Jiao T; Tratsiakovich Y; Yang J; Ostenson C-G; Pernow J; Zhou Z
Article: JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY. 2018;72(7):769-780
Erythrocytes From Patients With Type 2 Diabetes Induce Endothelial Dysfunction Via Arginase I
Zhou Z; Mahdi A; Tratsiakovich Y; Zahoran S; Kovamees O; Nordin F; Gonzalez AEU; Alvarsson M; Ostenson C-G; Andersson DC; Hedin U; Hermesz E; Lundberg JO; Yang J; Pernow J
Article: JACC: BASIC TO TRANSLATIONAL SCIENCE. 2018;3(4):450-463
Red Blood Cells in Type 2 Diabetes Impair Cardiac Post-Ischemic Recovery Through an Arginase-Dependent Modulation of Nitric Oxide Synthase and Reactive Oxygen Species
Yang J; Zheng X; Mahdi A; Zhou Z; Tratsiakovich Y; Jiao T; Kiss A; Kovamees O; Alvarsson M; Catrina S-B; Lundberg JO; Brismar K; Pernow J
Article: REDOX BIOLOGY. 2018;14:328-337
Identification of a soluble guanylate cyclase in RBCs: preserved activity in patients with. coronary artery disease
Cortese-Krott MM; Mergia E; Kramer CM; Lueckstaedt W; Yang J; Wolff G; Panknin C; Bracht T; Sitek B; Pernow J; Stasch J-P; Feelisch M; Koesling D; Kelm M
Article: ACTA PHYSIOLOGICA. 2017;221(3):174-181
Vagal nerve stimulation reduces infarct size via a mechanism involving the alpha-7 nicotinic acetylcholine receptor and downregulation of cardiac and vascular arginase
Kiss A; Tratsiakovich Y; Mahdi A; Yang J; Gonon AT; Podesser BK; Pernow J
Article: DIABETES AND VASCULAR DISEASE RESEARCH. 2017;14(3):236-245
Inhibition of Rho kinase protects from ischaemia-reperfusion injury via regulation of arginase activity and nitric oxide synthase in type 1 diabetes
Tratsiakovich Y; Kiss A; Gonon AT; Yang J; Sjoquist P-O; Pernow J
Journal article: ARTERIOSCLEROSIS, THROMBOSIS, AND VASCULAR BIOLOGY. 2017;37(suppl_1)
Abstract 378: Red Blood Cells From Patients With Type 2 Diabetes Induce Endothelial Dysfunction Through Up-Regulation of Arginase I
Zhou Z; Mahdi A; Tratsiakovich Y; Kövamees O; Yang J; Pernow J
Article: BASIC RESEARCH IN CARDIOLOGY. 2016;111(3):34
Dietary nitrate improves cardiac contractility via enhanced cellular Ca²⁺ signaling
Pironti G; Ivarsson N; Yang J; Farinotti AB; Jonsson W; Zhang S-J; Bas D; Svensson CI; Westerblad H; Weitzberg E; Lundberg JO; Pernow J; Lanner J; Andersson DC
Article: ACTA PHYSIOLOGICA. 2014;210(3):590-599
Adenosine increases LPS-induced nuclear factor kappa B activation in smooth muscle cells via an intracellular mechanism and modulates it via actions on adenosine receptors
Yang J; Zheng X; Haugen F; Dare E; Lovdahl C; Schulte G; Fredholm BB; Valen G
Article: PLOS ONE. 2014;9(8):e104731
The Role of Arginase and Rho Kinase in Cardioprotection from Remote Ischemic Perconditioning in Non-Diabetic and Diabetic Rat In Vivo
Kiss A; Tratsiakovich Y; Gonon AT; Fedotovskaya O; Lanner JT; Andersson DC; Yang J; Pernow J
Article: EUROPEAN JOURNAL OF PHARMACOLOGY. 2013;720(1-3):121-123
Arginase as a target for treatment of myocardial ischemia-reperfusion injury
Tratsiakovich Y; Yang J; Gonon AT; Sjoquist P-O; Pernow J
Article: INTERNATIONAL JOURNAL OF CARDIOLOGY. 2013;169(1):83-88
Myocardial protection by co-administration of L-arginine and tetrahydrobiopterin during ischemia and reperfusion
Tratsiakovich Y; Gonon AT; Kiss A; Yang J; Bohm F; Tornvall P; Settergren M; Channon KM; Sjoquist P-O; Pernow J
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2013;110(37):15049-15054
Arginase regulates red blood cell nitric oxide synthase and export of cardioprotective nitric oxide bioactivity
Yang J; Gonon AT; Sjoquist P-O; Lundberg JO; Pernow J
Journal article: EUROPEAN HEART JOURNAL. 2013;34(suppl_1):767
Arginase regulates formation and export of cardioprotective nitric oxide bioactivity from red blood cells
Yang J; Gonon AT; Sjöquist P-O; Lundberg JO; Pernow J
Journal article: EUROPEAN HEART JOURNAL. 2013;34(suppl_1):p5696
Myocardial protection by co-administration of L-arginine and tetrahydrobiopterin during ischemia and reperfusion
Tratsiakovich Y; Gonon AT; Kiss A; Yang J; Bohm F; Tornvall P; Settergren M; Channon KM; Sjoquist PO; Pernow J
Article: EUROPEAN JOURNAL OF PHARMACOLOGY. 2013;712(1-3):16-21
Arginase inhibition reduces infarct size via nitric oxide, protein kinase C epsilon and mitochondrial ATP-dependent K⁺ channels
Tratsiakovich Y; Gonon AT; Krook A; Yang J; Shemyakin A; Sjoquist P-O; Pernow J
Article: ACTA PHYSIOLOGICA. 2011;201(2):219-226
The combination of l-arginine and ischaemic post-conditioning at the onset of reperfusion limits myocardial injury in the pig
Gonon AT; Jung C; Yang J; Sjoquist P-O; Pernow J
Article: ACTA PHYSIOLOGICA. 2010;199(2):211-220
Adenosine A₁ receptors and vascular reactivity
Wang Y; Yang JN; Arner A; Boels PJM; Fredholm BB
Article: ACTA PHYSIOLOGICA. 2010;199(2):221-230
Adenosine A₃ receptors regulate heart rate, motor activity and body temperature
Yang JN; Wang Y; Garcia-Roves PM; Bjornholm M; Fredholm BB
Article: AMERICAN JOURNAL OF PHYSIOLOGY. HEART AND CIRCULATORY PHYSIOLOGY. 2009;296(4):H1141-H1149
Physiological roles of A₁ and A_2A adenosine receptors in regulating heart rate, body temperature, and locomotion as revealed using knockout mice and caffeine
Yang J-N; Chen J-F; Fredholm BB
Article: JOURNAL OF APPLIED PHYSIOLOGY. 2009;106(2):631-639
Mice heterozygous for both A₁ and A_2A adenosine receptor genes show similarities to mice given long-term caffeine
Yang J-N; Bjorklund O; Lindstrom-Tornqvist K; Lindgren E; Eriksson TM; Kahlstrom J; Chen J-F; Schwarzschild MA; Tobler I; Fredholm BB
Article: PHYSIOLOGY AND BEHAVIOR. 2008;95(5):668-676
Decreased behavioral activation following caffeine, amphetamine and darkness in A₃ adenosine receptor knock-out mice
Bjorklund O; Halldner-Henriksson L; Yang J; Eriksson TM; Jacobson MA; Dare E; Fredholm BB
Article: EUROPEAN JOURNAL OF PHARMACOLOGY. 2008;597(1-3):92-101
Adenosine A₁ receptors regulate lipolysis and lipogenesis in mouse adipose tissue - Interactions with insulin
JohanssonA SM; Lindgren E; Yang J-N; Herling AW; Fredholm BB
Article: BURNS. 2007;33(5):606-612
Small skin burn injury reduces cardiac tolerance to ischemia via a tumor necrosis factor alpha-dependent pathway
Labruto F; Pernow J; Yang J; Vaage J; Valen G
Journal article: BURNS. 2007;33(1):s4
Small skin burn injury reduces cardiac tolerance to ischemia via a tumor necrosis factor alpha-dependent pathway
Labruto F; Valen G; Vaage J; Yang J; Pernow J
Article: AMERICAN JOURNAL OF PHYSIOLOGY. HEART AND CIRCULATORY PHYSIOLOGY. 2006;290(4):H1469-H1473
Effect of modulating cardiac A1 adenosine receptor expression on protection with ischemic preconditioning.
Lankford AR; Yang J-N; Rose'Meyer R; French BA; Matherne GP; Fredholm BB; Yang Z
Article: BASIC RESEARCH IN CARDIOLOGY. 2005;100(3):198-207
Role of tumor necrosis factor alpha and its receptor I in preconditioning by hyperoxia
Labruto F; Yang JN; Vaage J; Valen G
Article: ACTA PHYSIOLOGICA. 2004;182(2):133-143
Adenosine A₁ receptors are necessary for protection of the murine heart by remote, delayed adaptation to ischaemia
Schulte G; Sommerschild H; Yang J; Tokuno S; Goiny M; Lövdahl C; Johansson B; Fredholm BB; Valen G
Journal article: EUROPEAN JOURNAL OF HEART FAILURE, SUPPLEMENT. 2003;2(1):135
620 The role of tumor necrosis factor alpha in preconditioning by hyperoxia
Labruto F; Yang J; Vaage J; Valen G
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All other publications

Conference publication: EUROPEAN HEART JOURNAL. 2022;43:2917
Red blood cells induce endothelial dysfunction in patients with ST-elevation myocardial infarction and elevated C-reactive protein
Tengbom J; Collado A; Jiao T; Yang J; Zhou Z; Mahdi A; Pernow J
Conference publication: EUROPEAN HEART JOURNAL. 2022;43:2921
Arginase 1 in erythrocytes is a critical modulator of cardioprotective signalling by nitric oxide and soluble guanylyl cyclase
Yang JN; Tratsiakovich YT; Jiao TJ; Mahdi AM; Tengbom JT; Zhou ZZ; Collado AC; Lundberg JL; Pernow JP
Conference publication: EUROPEAN HEART JOURNAL. 2022;43:2910
Erythrocytes from patients with ST-elevation myocardial infarction induce cardioprotection via the purinergic P2Y13 receptor and nitric oxide signalling
Jiao T; Mahdi A; Tengbom J; Collado A; Jurga J; Saleh N; Verouhis D; Bohm F; Zhou Z; Yang J; Pernow J
Conference publication: EUROPEAN HEART JOURNAL. 2022;43:3074
Overexpression of miR-210 ameliorates endothelial dysfunction in type 2 diabetic mice
Collado A; Jiao T; Zaccagnini G; Yang J; Carstrom M; Martelli F; Pernow J; Zhou Z
Conference publication: DIABETOLOGIA. 2022;65(SUPPL 1):S25
Overexpression of miR-210 attenuates endothelial dysfunction in a mouse model of obesity and type 2 diabetes
Collado A; Jiao T; Zaccagnini G; Yang J; Carlstrom M; Martelli F; Pernow J; Zhou Z
Conference publication: EUROPEAN HEART JOURNAL. 2021;42:3259
Attenuated cardiac post-ischemic injury and endothelial dysfunction by stimulation of soluble guanylyl cyclase in red blood cells from patients with type 2 diabetes
Jiao T; Zhou Z; Mahdi A; Tengbom J; Tratsiakovich Y; Yang J; Pernow J
Preprint: SSRN. 2021
Erythrocytes Induce Vascular Dysfunction in COVID-19
Mahdi A; Collado A; Tengbom J; Jiao T; Wodaje T; Johanssson N; Farnebo F; Färnert A; Yang J; Lundberg J; Zhou Z; Pernow J
Conference publication: EUROPEAN HEART JOURNAL. 2021;42:3364
Erythrocytes induce vascular dysfunction in COVID-19
Mahdi A; Collado A; Tengbom J; Jiao T; Wodaje T; Yang J; Lundberg JO; Zhou Z; Pernow J
Preprint: SSRN ELECTRONIC JOURNAL. 2021
Erythrocytes Induce Vascular Dysfunction in COVID-19
Mahdi A; Collado A; Tengbom J; Jiao T; Wodaje T; Johanssson N; Farnebo F; Färnert A; Yang J; Lundberg JO; Zhou Z; Pernow J
Review: CARDIOVASCULAR RESEARCH (CVR). 2019;115(11):1596-1605
Red blood cell dysfunction: a new player in cardiovascular disease
Pernow J; Mahdi A; Yang J; Zhou Z
Conference publication: EUROPEAN HEART JOURNAL. 2019;40:3903
Dietary nitrate restores cardiac ischemic tolerance in type 2 diabetic mice and protects against ischemia-reperfusion injury via soluble guanylate cyclase in red blood cells
Yang JN; Jiao T; Tratsiakovich Y; Mahdi A; Zhou Z; Lundberg JO; Pernow J
Conference publication: EUROPEAN HEART JOURNAL. 2019;40:894
A cardioprotective effect of dietary nitrate mediated by red blood cells
Jiao T; Yang JN; Sundqvist M; Tratsiakovich Y; Hellenius ML; Weitzberg E; Lundberg J; Pernow J
Editorial comment: AGING. 2018;10(12):3643-3644
Erythrocytes and cardiovascular complications
Zhou Z; Yang J; Pernow J
Conference publication: CARDIOVASCULAR RESEARCH (CVR). 2018;114:S42
Vascular endothelial growth factor receptor 2 inhibition improves endothelial function in type 2 diabetic rats: a link to purinergic signalling?
Mahdi A; Tratsiakovich Y; Yang J; Ostenson C-G; Danser JAH; Pernow J; Zhou Z
Conference publication: CARDIOVASCULAR RESEARCH (CVR). 2018;114:S26-S27
Inorganic nitrate restores cardiac ischemic tolerance in type 2 diabetic db/db mice and protects against ischemia-reperfusion injury via an effect mediated through red blood cells
Yang JN; Tratsiakovich Y; Mahdi A; Zhou Z; Lundberg JO; Pernow J
Conference publication: CARDIOVASCULAR RESEARCH (CVR). 2018;114:S42
Red blood cells from patients with type 2 diabetes mellitus induce endothelial dysfunction through NADPH oxidase-derived reactive oxygen species
Zhou Z; Mahdi A; Tratsiakovich Y; Yang J; Pernow J
Review: MOLECULAR ASPECTS OF MEDICINE. 2017;55:20-25
Low, but not high, dose caffeine is a readily available probe for adenosine actions
Fredholm BB; Yang J; Wang Y
Conference publication: EUROPEAN HEART JOURNAL. 2017;38:1140
Red blood cells from patients with type 2 diabetes impair post-ischemic cardiac recovery via a mechanism depending on arginase and nitric oxide synthase
Yang JN; Mahdi A; Zhou Z; Tratsiakovich Y; Kovamees O; Alvarsson M; Pernow J
Conference publication: EUROPEAN HEART JOURNAL. 2017;38:51-52
Red blood cells from patients with type 2 diabetes mellitus induce vascular endothelial dysfunction via a mechanism involving vascular arginase I and reactive oxygen species
Zhou Z; Mahdi A; Tratsiakovich Y; Kovamees O; Alvarsson M; Yang J; Pernow J
Conference publication: ARTERIOSCLEROSIS, THROMBOSIS, AND VASCULAR BIOLOGY. 2017;37
Red Blood Cells From Patients With Type 2 Diabetes Induce Endothelial Dysfunction Through Up-Regulation of Arginase I
Zhou Z; Mahdi A; Tratsiakovich Y; Kovamees O; Yang J; Pernow J
Conference publication: BIOPHYSICAL JOURNAL. 2016;110(3):598A-599A
Enhanced Cardiac Contractility and Ca²⁺ Signalling Following Dietary Nitrate Supplementation in Mice
Ivarsson N; Pironti G; Yang J; Farinotti AB; Jonsson W; Svensson C; Westerblad H; Weitzberg E; Lundberg J; Pernow J; Lanner J; Andersson DC
Conference publication: EUROPEAN HEART JOURNAL. 2015;36:526-527
Arginase inhibition protects from myocardial ischemia-reperfusion injury in rats with type 1 diabetes
Tratsiakovich Y; Kiss A; Yang J; Gonon AT; Sjoquist PO; Pernow J
Conference publication: EUROPEAN HEART JOURNAL. 2015;36:1208
Red blood cells impair post-ischemic cardiac function via arginase-dependent regulation of nitric oxide synthase and reactive oxygen species in type 2 diabetes
Yang JN; Zheng X; Tratsiakovich Y; Kiss A; Catarina S; Brismar K; Pernow J
Conference publication: EUROPEAN HEART JOURNAL. 2013;34:155-156
Arginase regulates formation and export of cardioprotective nitric oxide bioactivity from red blood cells
Yang J; Gonon AT; Sjoquist P-O; Lundberg JO; Pernow J
Conference publication: EUROPEAN HEART JOURNAL. 2013;34:1061
Myocardial protection by co-administration of L-arginine and tetrahydrobiopterin during ischemia and reperfusion
Tratsiakovich Y; Gonon AT; Kiss A; Yang J; Bohm F; Tornvall P; Settergren M; Channon KM; Sjoquist PO; Pernow J
Conference publication: EUROPEAN HEART JOURNAL. 2011;32:331
Arginase inhibition during myocardial ischemia reduces infarct size via increased production of nitric oxide, expression of protein kinase c and opening of mitochondrial ATP-dependent K channels
Tratsiakovich Y; Gonon AT; Krook A; Yang J; Sjoqvist P-O; Pernow J
Conference publication: EUROPEAN HEART JOURNAL. 2010;31:44
The combination of L-arginine and ischemic postconditioning at the onset of reperfusion limits myocardial injury in the pig
Gonon AT; Jung C; Yang J; Sjoquist P-O; Pernow J
Thesis / dissertation: 2008
Physiological roles of A1 and A2A adenosine receptors : studies using genetically modified mice
Yang, Jiang-Ning
Published conference paper: ACTA PHYSIOLOGICA. 2007;190(1):87-96
Eliminating the antilipolytic adenosine A₁ receptor does not lead to compensatory changes in the antilipolytic actions of PGE₂ and nicotinic acid
Johansson SM; Yang J-N; Lindgren E; Fredholm BB
Published conference paper: ACTA PHYSIOLOGICA. 2007;190(1):63-75
Sex differences in mouse heart rate and body temperature and in their regulation by adenosine A₁ receptors
Yang J-N; Tiselius C; Dare E; Johansson B; Valen G; Fredholm BB
Conference publication: ACTA PHARMACOLOGICA SINICA. 2006;27:182
Cardiovascular characterization of the adenosine A1 receptor knock-out mouse
Yang J; Tiselius C; Bian Z; Lövdahl C; Daré E; Edström E; Johansson B; Thorén P; Valen G; Fredholm BB
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Grants

The red blood cell: Mediator of cardiovascular disease and novel target for treatments
Swedish Research Council
1 January 2021 - 31 December 2024
Betydelsen av erytrocytdysfunktion för utveckling av kardiovaskulär sjukdom
Swedish Heart-Lung Foundation
1 January 2020 - 31 December 2022
Endothelial and red blood cell arginase-nitric oxide pathway in cardiovascular regulation with focus on ischemic heart disease and diabetes
Swedish Research Council
1 January 2017 - 31 December 2020
Drug and hypoxia induced fall in body temperature - new mechanisms and possible significance
Swedish Research Council
1 January 2010 - 31 December 2011

Employments

Senior Research Specialist, Department of Medicine, Karolinska Institutet, 2022-

Degrees and Education

Degree Of Doctor Of Philosophy, Department of Molecular Medicine and Surgery, Karolinska Institutet, 2008

Articles

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Grants

Employments

Degrees and Education

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