Jeroen Melief

Publications
Public outreach and news

Articles

Article: JOURNAL FOR IMMUNOTHERAPY OF CANCER. 2021;9(5):e002171

Predicting anti-PD-1 responders in malignant melanoma from the frequency of S100A9+monocytes in the blood

Pour SR; de Coana YP; Martinez Demorentin X; Melief J; Thimma M; Wolodarski M; Gomez-Cabrero D; Hansson J; Kiessling R; Tegner J
Article: CANCER IMMUNOLOGY IMMUNOTHERAPY. 2020;69(4):513-522

High expression of ID1 in monocytes is strongly associated with phenotypic and functional MDSC markers in advanced melanoma

Melief J; de Coana YP; Maas R; Fennemann F-L; Wolodarski M; Hansson J; Kiessling R
Article: ACTA NEUROPATHOLOGICA COMMUNICATIONS. 2019;7(1):60

Transcriptome analysis of normal-appearing white matter reveals cortisol- and disease-associated gene expression profiles in multiple sclerosis.

Melief J; Orre M; Bossers K; van Eden CG; Schuurman KG; Mason MRJ; Verhaagen J; Hamann J; Huitinga I
Article: METHODS IN MOLECULAR BIOLOGY. 2019;1913:133-140

Assessment of Antitumor T-Cell Responses by Flow Cytometry After Coculture of Tumor Cells with Autologous Tumor-Infiltrating Lymphocytes.

Melief J; Wickström S; Kiessling R; Pico de Coaña Y
Article: FRONTIERS IN IMMUNOLOGY. 2019;10:2766

Cancer Neoepitopes for Immunotherapy: Discordance Between Tumor-Infiltrating T Cell Reactivity and Tumor MHC Peptidome Display

Wickstrom SL; Loevgren T; Volkmar M; Reinhold B; Duke-Cohan JS; Hartmann L; Rebmann J; Mueller A; Melief J; Maas R; Ligtenberg M; Hansson J; Offringa R; Seliger B; Poschke I; Reinherz EL; Kiessling R
Article: FRONTIERS IN CELLULAR NEUROSCIENCE. 2018;12:110

Microglial Activation After Systemic Stimulation With Lipopolysaccharide and Escherichia coli.

Hoogland ICM; Westhoff D; Engelen-Lee J-Y; Melief J; Valls Serón M; Houben-Weerts JHMP; Huitinga I; van Westerloo DJ; van der Poll T; van Gool WA; van de Beek D
Article: CANCER IMMUNOLOGY IMMUNOTHERAPY. 2017;66(10):1333-1344

Enhanced stimulation of human tumor-specific T cells by dendritic cells matured in the presence of interferon-γ and multiple toll-like receptor agonists

Lovgren T; Sarhan D; Truxova I; Choudhary B; Maas R; Melief J; Nystrom M; Edback U; Vermeij R; Scurti G; Nishimura M; Masucci G; Karlsson-Parra A; Lundqvist A; Adamson L; Kiessling R
Article: ACTA NEUROPATHOLOGICA COMMUNICATIONS. 2017;5(1):16

Isolation of primary microglia from the human post-mortem brain: effects of ante- and post-mortem variables.

Mizee MR; Miedema SSM; van der Poel M; Adelia; Schuurman KG; van Strien ME; Melief J; Smolders J; Hendrickx DA; Heutinck KM; Hamann J; Huitinga I
Article: GLIA. 2016;64(11):1857-1868

Characterizing primary human microglia: A comparative study with myeloid subsets and culture models.

Melief J; Sneeboer MAM; Litjens M; Ormel PR; Palmen SJMC; Huitinga I; Kahn RS; Hol EM; de Witte LD
Article: JOURNAL OF NEUROIMMUNOLOGY. 2016;299:84-89

Glucocorticoid receptor haplotypes conferring increased sensitivity (BclI and N363S) are associated with faster progression of multiple sclerosis.

Melief J; Koper JW; Endert E; Møller HJ; Hamann J; Uitdehaag BM; Huitinga I
Article: ANNALS OF CLINICAL AND TRANSLATIONAL NEUROLOGY. 2014;1(8):618-621

Saffold cardiovirus and multiple sclerosis: no evidence for an association.

Galama JMD; Zoll JG; Lanke KH; de Jong AS; Melief J; Huitinga I; Verbeek MM; van Kuppeveld FJM
Article: NEUROBIOLOGY OF AGING. 2014;35(1):1-14

Acute isolation and transcriptome characterization of cortical astrocytes and microglia from young and aged mice.

Orre M; Kamphuis W; Osborn LM; Melief J; Kooijman L; Huitinga I; Klooster J; Bossers K; Hol EM
Article: GLIA. 2013;61(11):1848-1861

Microglia in normal appearing white matter of multiple sclerosis are alerted but immunosuppressed.

Melief J; Schuurman KG; van de Garde MDB; Smolders J; van Eijk M; Hamann J; Huitinga I
Article: ACTA NEUROPATHOLOGICA. 2013;126(4):525-535

Characteristics of differentiated CD8(+) and CD4 (+) T cells present in the human brain.

Smolders J; Remmerswaal EBM; Schuurman KG; Melief J; van Eden CG; van Lier RAW; Huitinga I; Hamann J
Article: ACTA NEUROPATHOLOGICA. 2013;126(2):237-249

HPA axis activity in multiple sclerosis correlates with disease severity, lesion type and gene expression in normal-appearing white matter.

Melief J; de Wit SJ; van Eden CG; Teunissen C; Hamann J; Uitdehaag BM; Swaab D; Huitinga I
Article: JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY. 2013;72(2):91-105

Expression of vitamin D receptor and metabolizing enzymes in multiple sclerosis-affected brain tissue.

Smolders J; Schuurman KG; van Strien ME; Melief J; Hendrickx D; Hol EM; van Eden C; Luchetti S; Huitinga I
Article: GLIA. 2012;60(10):1506-1517

Phenotyping primary human microglia: tight regulation of LPS responsiveness.

Melief J; Koning N; Schuurman KG; Van De Garde MDB; Smolders J; Hoek RM; Van Eijk M; Hamann J; Huitinga I

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Editorial comment: NATURE REVIEWS IMMUNOLOGY. 2023;23(6):345

Pancreatitis points to key role of dendritic cells in pancreatic cancer

Baldran-Groves L; Melief J
Review: ONCOGENE. 2021;40(2):421-435

Counteracting CAR T cell dysfunction

Poorebrahim M; Melief J; Pico de Coana Y; Wickstrom SL; Cid-Arregui A; Kiessling R
Review: HANDBOOK OF CLINICAL NEUROLOGY. 2021;181:119-126

The stress-axis in multiple sclerosis: Clinical, cellular, and molecular aspects.

Melief J; Huitinga I; Gold SM
Letter: BRAIN. 2010;133(Pt 5):e137

Epstein Barr virus is not a characteristic feature in the central nervous system in established multiple sclerosis.

Peferoen LAN; Lamers F; Lodder LNR; Gerritsen WH; Huitinga I; Melief J; Giovannoni G; Meier U; Hintzen RQ; Verjans GMGM; van Nierop GP; Vos W; Peferoen-Baert RMB; Middeldorp JM; van der Valk P; Amor S

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