Jennifer Härdfeldt

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About me

As a postdoctoral researcher in the Cardiometabolic Unit, my research focuses on cholesterol metabolism and unraveling the complex dynamics of lipoproteins and their pivotal role in atherogenesis. My research spans both acquired and inherited cardiometabolic diseases, aiming to bridge the gap between molecular mechanisms and clinical applications.

Articles

Journal article: ATHEROSCLEROSIS. 2022;355:8
Accelerated vascular ageing and retention of LDL in type 2 diabetes
Härdfeldt J; Björklund P; Angelin B; Öörni K; Rudling M; Straniero S
Article: JOURNAL OF INTERNAL MEDICINE. 2022;292(2):296-307
Soat2 ties cholesterol metabolism to β-oxidation and glucose tolerance in male mice
Pramfalk C; Ahmed O; Pedrelli M; Minniti ME; Luquet S; Denis RG; Olin M; Hardfeldt J; Vedin L-L; Steffensen KR; Ryden M; Hodson L; Eriksson M; Parini P
Article: BIOCHIMICA ET BIOPHYSICA ACTA - MOLECULAR AND CELL BIOLOGY OF LIPIDS. 2022;1867(2):159087
Abdominal obesity negatively influences key metrics of reverse cholesterol transport
Hardfeldt J; Cariello M; Simonelli S; Ossoli A; Scialpi N; Piglionica M; Pasculli E; Noia A; Berardi E; Suppressa P; Piazzolla G; Sabba C; Calabresi L; Moschetta A
Journal article: BIOCHIMICA ET BIOPHYSICA ACTA - MOLECULAR BASIS OF DISEASE. 2021;1867(6):166116
Intracoronary monocyte expression pattern and HDL subfractions after non-ST elevation myocardial infarction
Cariello M; Salvia R; Hardfeldt J; Piglionica M; Rutigliano D; Caldarola P; Ossoli A; Vacca M; Graziano G; Battaglia S; Zerlotin R; Arconzo M; Crudele L; Sabba C; Calabresi L; Moschetta A
Article: JOURNAL OF LIPID RESEARCH. 2020;61(4):480-491
Of mice and men: murine bile acids explain species differences in the regulation of bile acid and cholesterol metabolism[S]
Straniero S; Laskar A; Savva C; Hardfeldt J; Angelin B; Rudling M
Article: BIOCHIMICA ET BIOPHYSICA ACTA - MOLECULAR AND CELL BIOLOGY OF LIPIDS. 2019;1864(5):756-762
Effects on hepatic lipid metabolism in human hepatoma cells following overexpression of TGFβ induced factor homeobox 1 or 2
Hardfeldt J; Hodson L; Larsson L; Pedrelli M; Pramfalk C
Journal article: GASTROENTEROLOGY. 2018;155(5):1524-1538.e9
Deletion of Stearoyl-CoA Desaturase-1 From the Intestinal Epithelium Promotes Inflammation and Tumorigenesis, Reversed by Dietary Oleate
Ducheix S; Peres C; Hardfeldt J; Frau C; Mocciaro G; Piccinin E; Lobaccaro J-M; De Santis S; Chieppa M; Bertrand-Michel J; Plateroti M; Griffin JL; Sabba C; Ntambi JM; Moschetta A
Journal article: CARDIOVASCULAR RESEARCH (CVR). 2018;114(8):1154-1164
Identification of miR-9-5p as direct regulator of ABCA1 and HDL-driven reverse cholesterol transport in circulating CD14⁺ cells of patients with metabolic syndrome
D'Amore S; Hardfeldt J; Cariello M; Graziano G; Copetti M; Di Tullio G; Piglionica M; Scialpi N; Sabba C; Palasciano G; Vacca M; Moschetta A
Article: BIOCHIMICA ET BIOPHYSICA ACTA: INTERNATIONAL JOURNAL OF BIOCHEMISTRY AND BIOPHYSICS. 2016;1861(1):51-59
Culturing of HepG2 cells with human serum improve their functionality and suitability in studies of lipid metabolism
Pramfalk C; Larsson L; Hardfeldt J; Eriksson M; Parini P

All other publications

Thesis / dissertation: 2024
Exploring lipoprotein characteristics in human cardiometabolic disease
Härdfeldt, Jennifer
Conference publication: ATHEROSCLEROSIS. 2021;331:E128
MURINE BILE ACIDS EXPLAIN SPECIES DIFFERENCES IN THE REGULATION OF BILE ACID AND CHOLESTEROL METABOLISM
Straniero S; Laskar A; Savva C; Hardfeldt J; Angelin B; Rudling M
Conference publication: ATHEROSCLEROSIS. 2021;331:E7
INTERSTITIAL POSTPRANDIAL HYPERLIPIDEMIA AND REMNANT LIPOPROTEINS IN TYPE 2 DIABETES MELLITUS
Hardfeldt J; Bjorklund P; Angelin B; Rudling M; Straniero S
Meeting abstract: ATHEROSCLEROSIS. 2018;275:E25
GENETIC DEPLETION OF THE SOAT2 GENE DIMINISHES DIET-INDUCED HEPATIC STEATOSIS AND IMPROVES GLUCOSE TOLERANCE IN MICE
Pramfalk C; Ahmed O; Larsson L; Hardfeldt J; Pedrelli M; Vedin L; Steffensen K; Tellez M; Delbes A; Denis R; Luquet S; Eriksson M; Parini P

Employments

Postdoctoral Researcher, Department of Medicine, Huddinge, Karolinska Institutet, 2024-2026
Phd Student, Department of Medicine, Huddinge, Karolinska Institutet, 2019-2024
Clinical Position, ME Endokrinologi, Karolinska Universitetssjukhuset

Degrees and Education

Degree Of Doctor Of Philosophy, Department of Medicine, Huddinge, Karolinska Institutet, 2024

About me

Articles

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Employments

Degrees and Education

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