Jan Zedenius

About me
Publications
CV
Public outreach and news

Research

Research group leader of the group Endocrine Surgery.

Articles

Article: MOLECULAR CANCER THERAPEUTICS. 2025;:753-762
Dual-Nuclide Biodistribution and Therapeutic Evaluation of a Novel Antibody-Based Radiopharmaceutical in Anaplastic Thyroid Cancer Xenografts.
Lundgren Mortensen AC; Berglund H; Jha P; Stenman A; Selvaraju RK; Lundqvist H; Hofström C; Persson H; Juhlin CC; Zedenius J; Frejd FY; Nestor M
Article: JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM. 2025;110(3):693-705
BRAF-induced EHF Expression Affects TERT in Aggressive Papillary Thyroid Cancer
Xu Y; Gao J; Wang N; Zedenius J; Nilsson I-L; Lui W-O; Xu D; Juhlin CC; Larsson C; Mu N
Article: ENDOCRINE PATHOLOGY. 2024;35(4):411-418
Catching the Silent Culprits: TERT Promoter Mutation Screening of Minimally Invasive Follicular and Oncocytic Thyroid Carcinoma in Clinical Practice
Hellgren LS; Stenman A; Jatta K; Condello V; Larsson C; Zedenius J; Juhlin CC
Article: ENDOCRINE-RELATED CANCER. 2024;31(9):e230061
Genetic variants and down-regulation of CACNA1H in pheochromocytoma
Svahn F; Hose KS; Stenman A; Liu Y; Calissendorff J; Tham E; Vegvari A; Zubarev RA; Wang N; Korah R; Carling T; Zedenius J; Branstrom R; Juhlin CC; Larsson C
Article: JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM. 2024;109(7):1733-1744
Prevalence, Molecular Landscape, and Clinical Impact of DICER1 and DGCR8 Mutated Follicular-Patterned Thyroid Nodules
Condello V; Poma AM; Macerola E; Vignali P; Paulsson JO; Zedenius J; Basolo F; Juhlin CC
Article: ENDOCRINE PATHOLOGY. 2024;35(2):122-133
Spatial Transcriptomics in a Case of Follicular Thyroid Carcinoma Reveals Clone-Specific Dysregulation of Genes Regulating Extracellular Matrix in the Invading Front
Condello V; Paulsson JO; Zedenius J; Naesman A; Juhlin CC
Article: BJS OPEN. 2024;8(1):zrad154
Regional variations in the management of primary hyperparathyroidism in Sweden: population-based case-control study
Thorsteinsson D; Granath F; Branstrom R; Koman A; Zedenius J; Nilsson I-L
Article: CASE REPORTS IN ONCOLOGY. 2024;17(1):1124-1130
Immunotherapy and Tyrosine Kinase Inhibitor as a Bridge to Surgery for Clear Cell Renal Cell Carcinoma Metastases to the Thyroid: A Case Report and Literature Review
Branstrom R; Zedenius J; Shabo I; Lindskog M; Juhlin CC
Article: LANCET REGIONAL HEALTH-EUROPE. 2023;35:100769
Distinguishing between thyroid and parathyroid nodules by ultrasound: a potential game-changer in clinical practice?
Juhlin CC; Zedenius J
Article: ENDOCRINE. 2023;82(3):631-637
Adrenal and periadrenal schwannoma: histological, molecular and clinical characterization of an institutional case series
Stenman A; Falhammar H; Zedenius J; Juhlin CC
Article: JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY. 2023;71(8):451-458
5hmC Immunohistochemistry: A Predictor of TERT Promoter Mutational Status in Follicular Thyroid Carcinoma?
Hysek M; Hellgren SLL; Condello V; Xu Y; Larsson C; Zedenius J; Juhlin CC
Article: LAKARTIDNINGEN. 2023;120:23045
[Many adrenal incidentalomas are not adequately evaluated - updated guidelines to improve follow-up are presented].
Muth A; Sundin A; Zedenius J
Article: DIAGNOSTIC CYTOPATHOLOGY. 2023;51(6):331-340
Digital droplet PCR TERT promoter mutational screening in fine needle aspiration cytology of thyroid lesions: A highly specific technique for pre-operative identification of high-risk cases
Hysek M; Hellgren LS; Stenman A; Darai-Ramqvist E; Ljung E; Schliemann I; Condello V; Larsson C; Zedenius J; Jatta K; Juhlin CC
Journal article: EJSO. 2023;49(2):e29
Thyroglobulin expression, Ki-67 index, and lymph node ratio in papillary thyroid cancer – new insight into the prognostic assessment of PTC
Lindfors H; Ihre-Lundgren C; Zedenius J; Juhlin CC; Shabo I
Article: SCIENTIFIC REPORTS. 2023;13(1):1070
Thyroglobulin expression, Ki-67 index, and lymph node ratio in the prognostic assessment of papillary thyroid cancer
Lindfors H; Karlsen M; Karlton E; Zedenius J; Larsson C; Ihre Lundgren C; Juhlin CC; Shabo I
Article: ENDOCRINE PATHOLOGY. 2022;33(4):525-527
Papillary Thyroid Carcinoma with Desmoid-Like Fibromatosis: Double Trouble?
Juhlin CC; Hysek M; Stenman A; Zedenius J
Article: INTERNATIONAL JOURNAL OF ONCOLOGY. 2022;61(5):140
Altered expression of the IGF2-H19 locus and mitochondrial respiratory complexes in adrenocortical carcinoma
Scicluna P; Caramuta S; Kjellin H; Xu C; Froebom R; Akhtar M; Gao J; Shi H; Kjellman M; Almgren M; Hoog A; Zedenius J; Ekstroem TJ; Braenstroem R; Lui W-O; Larsson C
Journal article: HUMAN PATHOLOGY REPORTS. 2022;29:300656
Adrenal cortical adenoma arising in an adreno-hepatic fusion: Case report and literature review of a potential diagnostic pitfall
Stenman A; Shabo I; Zedenius J; Juhlin CC
Article: ENDOCRINE PATHOLOGY. 2022;33(2):231-242
Prognostic Utility of the Ki-67 Labeling Index in Follicular Thyroid Tumors: a 20-Year Experience from a Tertiary Thyroid Center
Hellgren LS; Stenman A; Paulsson JO; Hoog A; Larsson C; Zedenius J; Juhlin CC
Article: BIOMEDICINE & PHARMACOTHERAPY. 2022;149:112796
Synergistic effects of telomerase reverse transcriptase and regulator of telomere elongation helicase 1 on aggressiveness and outcomes in adrenocortical carcinoma
Yuan H; Wu Y; Wang J; Qin X; Huang Y; Yan L; Fana Y; Zedenius J; Juhlin CC; Larsson C; Lui W-O; Xu D
Article: THYROID RESEARCH. 2022;15(1):1
Synchronous lateral lymph node metastases from papillary and follicular thyroid carcinoma: case report and review of the literature
Stenman A; Kjellman M; Zedenius J; Juhlin CC
Article: DIAGNOSTIC CYTOPATHOLOGY. 2022;50(2):75-83
Cyto-morphological features of parathyroid lesions: Fine-needle aspiration cytology series from an endocrine tumor referral center
Steen S; Hysek M; Zedenius J; Falhammar H; Juhlin CC
Article: CANCERS. 2021;13(24):6340
Pan-Genomic Sequencing Reveals Actionable CDKN2A/2B Deletions and Kataegis in Anaplastic Thyroid Carcinoma
Stenman A; Yang M; Paulsson JO; Zedenius J; Paulsson K; Juhlin CC
Article: PATHOLOGY. 2021;53(7):852-859
Institutional characterisation of water clear cell parathyroid adenoma: a rare entity often unrecognised by TC-99m-sestamibi scintigraphy
Juhlin CC; Nilsson I-L; Falhammar H; Zedenius J
Article: ENDOCRINE PATHOLOGY. 2021;32(4):513-516
TERT Promoter Mutated Follicular Thyroid Carcinomas Exhibit a Distinct microRNA Expressional Profile with Potential Implications for Tumor Progression
Paulsson JO; Zedenius J; Juhlin CC
Article: JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM. 2021;106(11):3265-3282
Whole-genome Sequencing of Follicular Thyroid Carcinomas Reveal Recurrent Mutations in MicroRNA Processing Subunit DGCR8
Paulsson JO; Rafati N; DiLorenzo S; Chen Y; Haglund F; Zedenius J; Juhlin CC
Article: HISTOPATHOLOGY. 2021;79(4):661-666
Macrofollicular variant follicular thyroid tumors are DICER1 mutated and exhibit distinct histological features
Juhlin CC; Stenman A; Zedenius J
Journal article: HISTOPATHOLOGY. 2021;79(4):0i
Cover Image
Article: SCANDINAVIAN JOURNAL OF SURGERY. 2021;110(3):322-328
A Single Parathyroid Hormone Measurement Two Hours after a Thyroidectomy Reliably Predicts Permanent Hypoparathyroidism
Palmhag D; Brydolf J; Zedenius J; Branstrom R; Nilsson I-L
Article: THYROID RESEARCH. 2021;14(1):19
Development of metastatic poorly differentiated thyroid cancer from a sub-centimeter papillary thyroid carcinoma in a young patient with a germline MET mutation - association or random chance?
Johansson K; Stenman A; Paulsson JO; Wang N; Ihre-Lundgren C; Zedenius J; Juhlin CC
Article: WORLD JOURNAL OF SURGERY. 2021;45(7):2155-2164
The Clinical Significance of Lymph Node Ratio and Ki-67 Expression in Papillary Thyroid Cancer
Lindfors H; Ihre Lundgren C; Zedenius J; Juhlin CC; Shabo I
Article: HEAD AND NECK PATHOLOGY. 2021;15(2):628-637
Perithyroidal Salivary Gland Acinic Cell Carcinoma: Morphological and Molecular Attributes of a Unique Lesion
Juhlin CC; Asa SL; Jatta K; Rodsari HN; Shabo I; Haglund F; Delahunt B; Samaratunga H; Egevad L; Hoog A; Zedenius J
Article: EJSO. 2021;47(6):1364-1369
Metastasis to the thyroid gland: Characterization and survival of an institutional series spanning 28 years
Stergianos S; Juhlin CC; Zedenius J; Calissendorff J; Falhammar H
Article: JOURNAL OF CLINICAL PATHOLOGY. 2021;75(10):jclinpath-2021-207631-662
Nuclear-specific accumulation of telomerase reverse transcriptase (TERT) mRNA in TERT promoter mutated follicular thyroid tumours visualised by in situ hybridisation: a possible clinical screening tool?
Hellgren LS; Olsson A; Kaufeldt A; Paulsson JO; Hysek M; Stenman A; Zedenius J; Larsson C; Hoog A; Juhlin CC
Article: ENDOCRINE-RELATED CANCER. 2021;28(5):337-351
Pan-genomic characterization of high-risk pediatric papillary thyroid carcinoma
Stenman A; Backman S; Johansson K; Paulsson JO; Stalberg P; Zedenius J; Juhlin CC
Article: JOURNAL OF MOLECULAR DIAGNOSTICS. 2021;23(2):212-222
Spatial Distribution Patterns of Clinically Relevant TERT Promoter Mutations in Follicular Thyroid Tumors of Uncertain Malignant Potential Advantages of the Digital Droplet PCR Technique
Hysek M; Jatta K; Hellgren LS; Stenman A; Larsson C; Zedenius J; Juhlin CC
Article: BRAIN PATHOLOGY. 2021;31(1):61-69
TERTpromoter mutations in primary and secondary WHO grade III meningioma
Maier AD; Stenman A; Svahn F; Mirian C; Bartek JJ; Juhler M; Zedenius J; Broholm H; Mathiesen T
Article: FRONTIERS IN ENDOCRINOLOGY. 2021;12:724766
Parathyroid Adenoma With Respiratory-Like Epithelium: Case Report of a Potential Mimic With Unknown Etiology
Juhlin CC; Zedenius J
Article: ENDOCRINE PATHOLOGY. 2020;31(4):401-410
Clinical Routine Application of the Second-generation Neuroendocrine Markers ISL1, INSM1, and Secretagogin in Neuroendocrine Neoplasia: Staining Outcomes and Potential Clues for Determining Tumor Origin
Juhlin CC; Zedenius J; Hoog A
Article: BREAST CANCER RESEARCH AND TREATMENT. 2020;183(3):669-675
Sarcoma of the breast: breast cancer history as etiologic and prognostic factor-A population-based case-control study
Karlsson F; Granath F; Smedby KE; Zedenius J; Branstrom R; Nilsson I-L
Article: ENDOCRINE PATHOLOGY. 2020;31(2):156-165
Lipoadenoma of the Parathyroid Gland: Characterization of an Institutional Series Spanning 28 Years
Juhlin CC; Falhammar H; Zedenius J; Nilsson I-L; Hoog A
Article: SCANDINAVIAN JOURNAL OF SURGERY. 2020;109(2):133-142
Impact of immunohistochemistry on the diagnosis and management of primary aldosteronism: An important tool for improved patient follow-up
Volpe C; Hamberger B; Zedenius J; Juhlin CC
Article: ENDOCRINE-RELATED CANCER. 2020;27(5):295-308
GABPA-dependent down-regulation of DICER1 in follicular thyroid tumours
Paulsson JO; Wang N; Gao J; Stenman A; Zedenius J; Mu N; Lui W-O; Larsson C; Juhlin CC
Article: ENDOCRINE PATHOLOGY. 2020;31(1):77-83
Metastatic Anaplastic Thyroid Carcinoma in Complete Remission: Morphological, Molecular, and Clinical Work-Up of a Rare Case
Stenman A; Hellgren LS; Jatta K; Hysek M; Zemmler M; Altena R; Nilsson I-L; Branstrom R; Zedenius J; Juhlin CC
Article: JOURNAL OF PATHOLOGY. 2020;250(2):183-194
Whole-genome sequencing of synchronous thyroid carcinomas identifies aberrant DNA repair in thyroid cancer dedifferentiation
Paulsson JO; Backman S; Wang N; Stenman A; Crona J; Thutkawkorapin J; Ghaderi M; Tham E; Stalberg P; Zedenius J; Juhlin CC
Article: EPIGENETICS. 2019;14(12):1224-1233
Telomerase activation in small intestinal neuroendocrine tumours is associated with aberrant TERT promoter methylation, but not hot-spot mutations
Fotouhi O; Ghaderi M; Wang N; Zedenius J; Kjellman M; Xu D; Juhlin CC; Larsson C
Article: DIAGNOSTIC PATHOLOGY. 2019;14(1):127
Signet ring cell variant of follicular thyroid carcinoma: Report of two cases with focus on morphological, expressional and genetic characteristics
Hysek M; Jatta K; Stenman A; Darai-Ramqvist E; Zedenius J; Hoog A; Juhlin CC
Article: SURGERY. 2019;166(5):901-906
Retrospective application of the pathologic tumor-node-metastasis classification system for pheochromocytoma and abdominal paraganglioma in a well characterized cohort with long-term follow-up
Stenman A; Zedenius J; Juhlin CC
Article: ONCOGENE. 2019;38(43):6881-6897
Proteomics identifies neddylation as a potential therapy target in small intestinal neuroendocrine tumors
Fotouhi O; Kjellin H; Juhlin CC; Pan Y; Vesterlund M; Ghaderi M; Yousef A; Andersson-Sand H; Kharaziha P; Caramuta S; Kjellman M; Zedenius J; Larsson C; Orre LM
Article: CANCERS. 2019;11(10):E1443-1443
Clinical Routine TERT Promoter Mutational Screening of Follicular Thyroid Tumors of Uncertain Malignant Potential (FT-UMPs): A Useful Predictor of Metastatic Disease
Hysek M; Paulsson JO; Jatta K; Shabo I; Stenman A; Hoog A; Larsson C; Zedenius J; Juhlin CC
Article: ENDOCRINE PATHOLOGY. 2019;30(3):246-248
TERT Promoter Mutation Spatial Heterogeneity in a Metastatic Follicular Thyroid Carcinoma: Implications for Clinical Work-Up
Stenman A; Hysek M; Jatta K; Branstrom R; Darai-Ramqvist E; Paulsson JO; Wang N; Larsson C; Zedenius J; Juhlin CC
Article: LAKARTIDNINGEN. 2019;116:FHM3
[Endocrine tumours in Stockholm - increasing general incidence].
Juhlin CC; Stenman A; Zedenius J
Article: AMERICAN JOURNAL OF SURGICAL PATHOLOGY. 2019;43(3):409-421
Molecular Profiling of Pheochromocytoma and Abdominal Paraganglioma Stratified by the PASS Algorithm Reveals Chromogranin B as Associated With Histologic Prediction of Malignant Behavior
Stenman A; Svahn F; Hojjat-Farsangi M; Zedenius J; Soderkvist P; Gimm O; Larsson C; Juhlin CC
Article: VIRCHOWS ARCHIV. 2018;473(5):639-643
TERT promoter mutational screening as a tool to predict malignant behaviour in follicular thyroid tumours-three examples from the clinical routine
Hysek M; Paulsson JO; Wang N; Jatta K; Lindh C; Fuentes-Martinez N; Shabo I; Zedenius J; Juhlin CC
Article: NEUROENDOCRINOLOGY LETTERS. 2018;39(4):305-309
Regional differences in somatostatin receptor 2 (SSTR2) immunoreactivity is coupled to level of bowel invasion in small intestinal neuroendocrine tumors
Fotouhi O; Zedenius J; Hoog A; Juhlin CC
Article: LANGENBECKS ARCHIVES OF SURGERY. 2018;403(6):785-790
Over-diagnosis of potential malignant behavior in MEN 2A-associated pheochromocytomas using the PASS and GAPP algorithms
Stenman A; Zedenius J; Juhlin CC
Article: ENDOCRINE. 2018;61(2):293-302
High Ki-67 index in fine needle aspiration cytology of follicular thyroid tumors is associated with increased risk of carcinoma
Mu N; Juhlin CC; Tani E; Sofiadis A; Reihner E; Zedenius J; Larsson C; Nilsson I-L
Article: BMC ENDOCRINE DISORDERS. 2018;18(1):46
Papillary thyroid carcinoma with pleomorphic tumor giant cells in a pregnant woman - a case report
Paulsson JO; Zedenius J; Juhlin CC
Article: ENDOCRINE-RELATED CANCER. 2018;25(7):723-733
TERT aberrancies: a screening tool for malignancy in follicular thyroid tumours
Paulsson JO; Mu N; Shabo I; Wang N; Zedenius J; Larsson C; Juhlin CC
Article: WORLD JOURNAL OF SURGERY. 2018;42(3):632-638
Recovery of Voice After Reconstruction of the Recurrent Laryngeal Nerve and Adjuvant Nimodipine
Mattsson P; Frostell A; Bjorck G; Persson JKE; Hakim R; Zedenius J; Svensson M
Article: LAKARTIDNINGEN. 2017;114:ETTI
[Finally! A new program for adrenal incidentaloma].
Zedenius J
Article: SURGERY. 2017;162(2):429-436
Primary hyperparathyroidism, hypercalciuria, and bone recovery after parathyroidectomy
Nilsson I-L; Norenstedt S; Zedenius J; Pernow Y; Branstrom R
Article: JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM. 2016;101(10):3616-3627
Proteomics Suggests a Role for APC-Survivin in Response to Somatostatin Analog Treatment of Neuroendocrine Tumors
Fotouhi O; Kjellin H; Larsson C; Hashemi J; Barriuso J; Juhlin CC; Lu M; Hoog A; Pastrian LG; Lamarca A; Heredia Soto V; Zedenius J; Mendiola M; Lehtio J; Kjellman M
Article: ENDOCRINE. 2016;53(2):505-511
Minimally invasive follicular thyroid carcinomas: prognostic factors
Stenson G; Nilsson I-L; Mu N; Larsson C; Lundgren CI; Juhlin CC; Hoog A; Zedenius J
Article: ONCOTARGET. 2016;7(16):21332-21346
Genetic and epigenetic background and protein expression profiles in relation to telomerase activation in medullary thyroid carcinoma
Wang N; Kjellin H; Sofiadis A; Fotouhi O; Juhlin CC; Backdahl M; Zedenius J; Xu D; Lehtio J; Larsson C
Article: SURGERY. 2016;159(1):211-217
FGF23, metabolic risk factors, and blood pressure in patients with primary hyperparathyroidism undergoing parathyroid adenomectomy
Nilsson I-L; Norenstedt S; Granath F; Zedenius J; Pernow Y; Larsson TE
Article: ENDOCRINE-RELATED CANCER. 2015;22(5):735-744
Novel somatic mutations and distinct molecular signature in aldosterone-producing adenomas
Akerstrom T; Willenberg HS; Cupisti K; Ip J; Backman S; Moser A; Maharjan R; Robinson B; Iwen KA; Dralle H; Volpe CD; Backdahl M; Botling J; Stalberg P; Westin G; Walz MK; Lehnert H; Sidhu S; Zedenius J; Bjorklund P; Hellman P
Article: EXPERIMENTAL CELL RESEARCH. 2015;336(1):158-170
Secretome protein signature of human gastrointestinal stromal tumor cells
Berglund E; Dare E; Branca RMM; Akcakaya P; Frobom R; Berggren P-O; Lui W-O; Larsson C; Zedenius J; Orre L; Lehtio J; Kim J; Branstrom R
Article: CLINICAL ENDOCRINOLOGY. 2015;82(5):639-647
Primary aldosteronism: functional histopathology and long-term follow-up after unilateral adrenalectomy
Volpe C; Hamberger B; Hoog A; Mukai K; Calissendorff J; Wahrenberg H; Zedenius J; Thoren M
Article: HUMAN MOLECULAR GENETICS. 2015;24(8):2318-2329
Characterization of the mutational landscape of anaplastic thyroid cancer via whole-exome sequencing
Kunstman JW; Juhlin CC; Goh G; Brown TC; Stenman A; Healy JM; Rubinstein JC; Choi M; Kiss N; Nelson-Williams C; Mane S; Rimm DL; Prasad ML; Hoog A; Zedenius J; Larsson C; Korah R; Lifton RP; Carling T
Article: EUROPEAN JOURNAL OF ENDOCRINOLOGY. 2015;172(2):181-187
Health-related quality of life after successful surgery for primary hyperparathyroidism: no additive effect from vitamin D supplementation: results of a double-blind randomized study
Aberg V; Norenstedt S; Zedenius J; Saaf M; Nordenstrom J; Pernow Y; Nilsson I-L
Article: PLOS ONE. 2015;10(5):e0126472
Differential Protein Expression Profiles of Cyst Fluid from Papillary Thyroid Carcinoma and Benign Thyroid Lesions
Dinets A; Pernemalm M; Kjellin H; Sviatoha V; Sofiadis A; Juhlin CC; Zedenius J; Larsson C; Lehtio J; Hoog A
Article: CLINICAL CANCER RESEARCH. 2014;20(22):5733-5744
Human Anaplastic Thyroid Carcinoma Cells Are Sensitive to NK Cell-Mediated Lysis via ULBP2/5/6 and Chemoattract NK Cells
Wennerberg E; Pfefferle A; Ekblad L; Yoshimoto Y; Kremer V; Kaminskyy VO; Juhlin CC; Hoog A; Bodin I; Svjatoha V; Larsson C; Zedenius J; Wennerberg J; Lundqvist A
Article: ONCOGENE. 2014;33(42):4978-4984
The age- and shorter telomere-dependent TERT promoter mutation in follicular thyroid cell-derived carcinomas
Liu T; Wang N; Cao J; Sofiadis A; Dinets A; Zedenius J; Larsson C; Xu D
Article: CANCER. 2014;120(19):2965-2979
TERT Promoter Mutation as an Early Genetic Event Activating Telomerase in Follicular Thyroid Adenoma (FTA) and Atypical FTA
Wang N; Liu T; Sofiadis A; Juhlin CC; Zedenius J; Hoog A; Larsson C; Xu D
Article: EXPERIMENTAL CELL RESEARCH. 2014;326(2):315-325
Functional role of the Ca²⁺-activated Cl^- channel DOG1/TMEM16A in gastrointestinal stromal tumor cells
Berglund E; Akcakaya P; Berglund D; Karlsson F; Vukojevic V; Lee L; Bogdanovic D; Lui W-O; Larsson C; Zedenius J; Frobom R; Branstrom R
Article: JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM. 2014;99(8):E1571-E1579
Telomerase-Dependent and Independent Telomere Maintenance and its Clinical Implications in Medullary Thyroid Carcinoma
Wang N; Xu D; Sofiadis A; Hoog A; Vukojevic V; Backdahl M; Zedenius J; Larsson C
Article: EPIGENETICS. 2014;9(7):987-997
Global hypomethylation and promoter methylation in small intestinal neuroendocrine tumors An in vivo and in vitro study
Fotouhi O; Fahmideh MA; Kjellman M; Sulaiman L; Hoog A; Zedenius J; Hashemi J; Larsson C
Article: EUROPEAN JOURNAL OF ENDOCRINOLOGY. 2014;170(4):583-591
MicroRNA expression patterns associated with hyperfunctioning and non-hyperfunctioning phenotypes in adrenocortical adenomas
Velazquez-Fernandez D; Caramuta S; Ozata DM; Lu M; Hoog A; Backdahl M; Larsson C; Lui W-O; Zedenius J
Article: ANTI-CANCER DRUGS. 2014;25(4):415-422
Intracellular concentration of the tyrosine kinase inhibitor imatinib in gastrointestinal stromal tumor cells
Berglund E; Ubhayasekera SJKA; Karlsson F; Akcakaya P; Aluthgedara W; Ahlen J; Frobom R; Nilsson I-L; Lui W-O; Larsson C; Zedenius J; Bergquist J; Branstrom R
Article: JOURNAL OF BONE AND MINERAL RESEARCH. 2014;29(4):960-967
Vitamin D Supplementation After Parathyroidectomy: Effect on Bone Mineral Density-A Randomized Double-Blind Study
Norenstedt S; Pernow Y; Zedenius J; Nordenstrom J; Saaf M; Granath F; Nilsson I-L
Article: EUROPEAN JOURNAL OF ENDOCRINOLOGY. 2013;169(6):795-804
Primary hyperparathyroidism and metabolic risk factors, impact of parathyroidectomy and vitamin D supplementation, and results of a randomized double-blind study
Norenstedt S; Pernow Y; Brismar K; Saaf M; Ekip A; Granath F; Zedenius J; Nilsson I-L
Article: BMC CANCER. 2013;13:505
Copy number alterations in small intestinal neuroendocrine tumors determined by array comparative genomic hybridization
Hashemi J; Fotouhi O; Sulaiman L; Kjellman M; Hoog A; Zedenius J; Larsson C
Article: BRITISH JOURNAL OF SURGERY. 2013;100(11):1505-1514
Outcome after resection and radiofrequency ablation of liver metastases from small intestinal neuroendocrine tumours
Norlen O; Stalberg P; Zedenius J; Hellman P
Article: ENDOCRINE-RELATED CANCER. 2013;20(4):551-564
Clinical and functional impact of TARBP2 over-expression in adrenocortical carcinoma
Caramuta S; Lee L; Ozata DM; Akcakaya P; Xie H; Hoog A; Zedenius J; Backdahl M; Larsson C; Lui W-O
Article: EXPERIMENTAL CELL RESEARCH. 2013;319(8):1229-1238
Evidence for Ca²⁺-regulated ATP release in gastrointestinal stromal tumors
Berglund E; Berglund D; Akcakaya P; Ghaderi M; Dare E; Berggren P-O; Kohler M; Aspinwall CA; Lui W-O; Zedenius J; Larsson C; Branstrom R
Article: JOURNAL OF SURGICAL ONCOLOGY. 2012;106(8):981-986
Anaplastic carcinoma of the thyroid gland: Treatment and outcome over 13 years at one institution
Segerhammar I; Larsson C; Nilsson I-L; Backdahl M; Hoog A; Wallin G; Foukakis T; Zedenius J
Article: EUROPEAN JOURNAL OF ENDOCRINOLOGY. 2012;166(6):1049-1060
Clinical, genetic, and immunohistochemical characterization of 70 Ukrainian adult cases with post-Chornobyl papillary thyroid carcinoma
Dinets A; Hulchiy M; Sofiadis A; Ghaderi M; Hoog A; Larsson C; Zedenius J
Article: EUROPEAN JOURNAL OF ENDOCRINOLOGY. 2012;166(4):657-667
Proteomic profiling of follicular and papillary thyroid tumors
Sofiadis A; Becker S; Hellman U; Hultin-Rosenberg L; Dinets A; Hulchiy M; Zedenius J; Wallin G; Foukakis T; Hoog A; Auer G; Lehtio J; Larsson C
Journal article: JOURNAL OF CANCER THERAPEUTICS & RESEARCH. 2012;1(1):11
Side-effects from imatinib treatment of advanced GIST–associated with a better outcome
Åhlén J; Westerdahl J; Zedenius J; Bränström R; Larsson C; Nilsson I-L
Article: PLOS ONE. 2012;7(7):e41926
Comprehensive Re-Sequencing of Adrenal Aldosterone Producing Lesions Reveal Three Somatic Mutations near the KCNJ5 Potassium Channel Selectivity Filter
Akerstrom T; Crona J; Verdugo AD; Starker LF; Cupisti K; Willenberg HS; Knoefel WT; Saeger W; Feller A; Ip J; Soon P; Anlauf M; Alesina PF; Schmid KW; Decaussin M; Levillain P; Wangberg B; Peix J-L; Robinson B; Zedenius J; Backdahl M; Caramuta S; Iwen KA; Botling J; Stalberg P; Kraimps J-L; Dralle H; Hellman P; Sidhu S; Westin G; Lehnert H; Walz MK; Akerstrom G; Carling T; Choi M; Lifton RP; Bjorklund P
Article: WORLD JOURNAL OF SURGERY. 2011;35(12):2691-2697
Thyroid Incidentaloma Detected by Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography: Practical Management Algorithm
Nilsson I-L; Arnberg F; Zedenius J; Sundin A
Article: ENDOCRINE-RELATED CANCER. 2011;18(6):643-655
The role of microRNA deregulation in the pathogenesis of adrenocortical carcinoma
Ozata DM; Caramuta S; Velazquez-Fernandez D; Akcakaya P; Xie H; Hoog A; Zedenius J; Backdahl M; Larsson C; Lui W-O
Article: CLINICAL EPIDEMIOLOGY. 2011;3:103-106
Breast cancer associated with primary hyperparathyroidism: a nested case control study.
Norenstedt S; Granath F; Ekbom A; Bergh J; Lambe M; Adolfsson J; Warnberg F; Zedenius J; Nilsson I-L
Article: THYROID. 2010;20(10):1067-1076
Proteomic Study of Thyroid Tumors Reveals Frequent Up-Regulation of the Ca²⁺-Binding Protein S100A6 in Papillary Thyroid Carcinoma
Sofiadis A; Dinets A; Orre LM; Branca RM; Juhlin CC; Foukakis T; Wallin G; Hoog A; Hulchiy M; Zedenius J; Larsson C; Lehtio J
Article: ANNALS OF OTOLOGY RHINOLOGY AND LARYNGOLOGY. 2009;118(7):506-511
Diagnosis and Prognosis of Iatrogenic Injury of the Recurrent Laryngeal Nerve
Hydman J; Bjorck G; Persson JKE; Zedenius J; Mattsson P
Article: INTERNATIONAL JOURNAL OF ONCOLOGY. 2009;35(2):369-374
Diagnostic and prognostic potential of MIB-1 proliferation index in thyroid fine needle aspiration biopsy
Sofiadis A; Tani E; Foukakis T; Kjellman P; Skoog L; Hoog A; Wallin G; Zedenius J; Larsson C
Article: EUROPEAN JOURNAL OF ENDOCRINOLOGY. 2009;160(2):295-299
Postoperative mortality in parathyroid surgery in Sweden during five decades: improved outcome despite older patients
Norenstedt S; Ekbom A; Brandt L; Zedenius J; Nilsson I-L
Article: WORLD JOURNAL OF SURGERY. 2008;32(7):1247-1252
Fine-needle aspiration biopsy of benign thyroid nodules: An evidence-based review
Lundgren CI; Zedenius J; Skoog L
Article: ENDOCRINE-RELATED CANCER. 2007;14(2):381-391
A PCR-based expression signature of malignancy in follicular thyroid tumors
Foukakis T; Gusnanto A; Au AYM; Hoog A; Lui W-O; Larsson C; Wallin G; Zedenius J
Article: BRITISH JOURNAL OF SURGERY. 2007;94(5):571-577
Influence of surgical and postoperative treatment on survival in differentiated thyroid cancer
Lundgren CI; Hall P; Dickman PW; Zedenius J
Article: ENDOCRINE-RELATED CANCER. 2007;14(1):135-140
The association between primary hyperparathyroidism and malignancy: nationwide cohort analysis on cancer incidence after parathyroidectomy
Nilsson I-L; Zedenius J; Yin L; Ekbom A
Article: SCANDINAVIAN JOURNAL OF SURGERY. 2007;96(1):26-30
Operation for primary hyperparathyroidism:: The new versus the old order -: A randomised controlled trial of preoperative localisation
Aarum S; Nordenstroem J; Reihner E; Zedenius J; Jacobsson H; Danielsson R; Baeckdahl M; Lindholm H; Wallin G; Hamberger B; Farnebo L-O
Article: THYROID. 2006;16(7):659-666
Are possible risk factors for differentiated thyroid cancer of prognostic importance?
Lundgren CI; Dickman PW; Zedenius J; Hall P
Article: EJSO. 2006;32(3):345-352
Predictors of outcome in patients with papillary thyroid carcinoma
Kjellman P; Zedenius J; Lundell G; Bäckdahl M; Farnebo LO; Hamberger B; Larsson C; Wallin G
Article: JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM. 2006;91(3):1143-1149
The Ras effector NORE1A is suppressed in follicular thyroid carcinomas with a PAX8-PPARγ fusion
Foukakis T; Au AYM; Wallin G; Geli J; Forsberg L; Clifton-Bligh R; Robinson BG; Lui WO; Zedenius J; Larsson C
Article: CANCER. 2006;106(3):524-531
Clinically significant prognostic factors for differentiated thyroid carcinoma - A population-based, nested case-control study
Lundgren CI; Hall P; Dickman PW; Zedenius J
Article: JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM. 2006;91(1):262-269
High frequency of loss of heterozygosity in imprinted, compared with nonimprinted, genomic regions in follicular thyroid carcinomas and atypical adenomas
Sarquis MS; Weber F; Shen L; Broelsch CE; Jhiang SM; Zedenius J; Frilling A; Eng C
Article: EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY & DIABETES. 2005;113(9):516-521
Lack of mutations in the TSHr and Gsα genes in TSHr antibody negative Graves' disease
Elgadi A; Frisk T; Larsson C; Wallin G; Höög A; Zedenius J; Norgren S
Article: EUROPEAN JOURNAL OF ENDOCRINOLOGY. 2005;152(3):459-470
Distinction in gene expression profiles demonstrated in parathyroid adenomas by high-density oligoarray technology
Forsberg L; Björck E; Hashemi J; Zedenius J; Höög A; Farnebo LO; Reimers M; Larsson C
Article: ONCOGENE. 2005;24(8):1467-1476
Expression profiling reveals a distinct transcription signature in follicular thyroid carcinomas with a PAX8-PPARγ fusion oncogene
Lui WO; Foukakis T; Lidén J; Thoppe SR; Dwight T; Höög A; Zedenius J; Wallin G; Reimers M; Larsson C
Article: INTERNATIONAL JOURNAL OF ONCOLOGY. 2005;26(1):141-149
Molecular cytogenetic characterization of primary cultures and established cell lines from non-medullary thyroid tumors
Foukakis T; Thoppe SR; Lagercrantz S; Dwight T; Weng WH; Svensson A; Höög A; Zedenius J; Wallin G; Lui WO; Larsson C
Article: INTERNATIONAL JOURNAL OF CANCER. 2003;106(4):569-573
Incidence and survival of Swedish patients with differentiated thyroid cancer
Lundgren CI; Hall P; Ekbom A; Frisell J; Zedenius J; Dickman PW
Article: JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM. 2003;88(9):4440-4445
Involvement of the PAX8/peroxisome proliferator-activated receptor γ rearrangement in follicular thyroid tumors
Dwight T; Thoppe SR; Foukakis T; Lui WO; Wallin G; Höög A; Frisk T; Larsson C; Zedenius J
Article: THYROID. 2003;13(4):371-380
MIB-1 index in thyroid tumors:: A predictor of the clinical course in papillary thyroid carcinoma?
Kjellman P; Wallin G; Höög A; Auer G; Larsson C; Zedenius J
Article: AMERICAN JOURNAL OF PATHOLOGY. 2002;161(4):1299-1306
Independent genetic events associated with the development of multiple parathyroid tumors in patients with primary hyperparathyroidism
Dwight T; Nelson AE; Theodosopoulos G; Richardson AL; Learoyd DL; Philips J; Delbridge L; Zedenius J; Teh BT; Larsson C; Marsh DJ; Robinson BG
Article: GENES CHROMOSOMES & CANCER. 2002;35(1):74-80
Silencing of the PTEN tumor-suppressor gene in anaplastic thyroid cancer
Frisk T; Foukakis T; Dwight T; Lundberg J; Höög A; Wallin G; Eng C; Zedenius J; Larsson C
Journal article: CURRENT OPINION IN ENDOCRINOLOGY DIABETES AND OBESITY. 2002;9(1):43-50
Follicular thyroid tumors: clinical and genetic aspects
Frisk T; Larsson C; Wallin G; Zedenius J
Article: GENES CHROMOSOMES & CANCER. 2001;32(1):43-49
Gain of 1q and loss of 9q21.3-q32 are associated with a less favorable prognosis in papillary thyroid carcinoma
Kjellman P; Lagercrantz S; Höög A; Wallin G; Larsson C; Zedenius J
Article: LAKARTIDNINGEN. 2001;98(25):3024-3028
[Hereditary thyroid cancer can be cured by prophylactic surgery].
Wallin G; Bondesson AG; Farnebo LO; Hallengren B; Hamberger B; Jansson S; Nilsson O; Nordenskjöld M; Smeds S; Svensson KA; Wihlborg O; Zedenius J
Article: INTERNATIONAL JOURNAL OF ONCOLOGY. 2001;18(6):1219-1225
CGH alterations in medullary thyroid carcinomas in relation to the RET M918T mutation and clinical outcome
Frisk T; Zedenius J; Lundberg J; Wallin G; Kytölä S; Larsson C
Article: THYROID. 2001;11(2):187-192
Surgical treatment of hyperthyroidism:: A ten-year experience
Werga-Kjellman P; Zedenius J; Tallstedt L; Träisk F; Lundel G; Wallin G
Article: CLINICAL ENDOCRINOLOGY. 2000;53(1):85-92
Loss of heterozygosity in sporadic parathyroid tumours:: involvement of chromosome 1 and the MEN1 gene locus in 11q13.
Dwight T; Twigg S; Delbridge L; Wong FK; Farnebo F; Richardson AL; Nelson A; Zedenius J; Philips J; Larsson C; Teh BT; Robinson B
Article: EUROPEAN JOURNAL OF ENDOCRINOLOGY. 2000;142(6):643-649
Expression of RET and its ligand complexes, GDNF/GFRalpha-1 and NTN/GFRalpha-2, in medullary thyroid carcinomas
Frisk T; Farnebo F; Zedenius J; Grimelius L; Höög A; Wallin G; Larsson C
Article: GENES CHROMOSOMES & CANCER. 1999;26(4):322-328
Fine-structure deletion mapping of 10q22-24 identifies regions of loss of heterozygosity and suggests that sporadic follicular thyroid adenomas and follicular thyroid carcinomas develop along distinct neoplastic pathways
Yeh JJ; Marsh DJ; Zedenius J; Dwight T; Delbridge L; Robinson BG; Eng C
Article: GENES CHROMOSOMES & CANCER. 1999;26(1):35-39
Sporadic follicular thyroid tumors show loss of a 200-kb region in 11q13 without evidence for mutations in the MEN1 gene
Nord B; Larsson C; Wong FK; Wallin G; Teh BT; Zedenius J
Article: GENES CHROMOSOMES & CANCER. 1999;25(4):349-353
Low frequency of numerical chromosomal aberrations in follicular thyroid tumors detected by comparative genomic hybridization
Frisk T; Kytölä S; Wallin G; Zedenius J; Larsson C
Article: ANZ JOURNAL OF SURGERY. 1999;69(1):34-36
Multinodular goitre presenting as a clinical single nodule:: How effective is hemithyroidectomy?
Wadström C; Zedenius J; Guinea A; Reeve T; Delbridge L
Article: JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM. 1998;83(10):3631-3635
RET/PTC and RET tyrosine kinase expression in adult papillary thyroid carcinomas
Learoyd DL; Messina M; Zedenius J; Guinea AI; Delbridge LW; Robinson BG
Article: ANNALS OF SURGERY. 1998;228(1):99-105
Thymic carcinoids in multiple endocrine neoplasia type 1
Teh BT; Zedenius J; Kytölä S; Skogseid B; Trotter J; Choplin H; Twigg S; Farnebo F; Giraud S; Cameron D; Robinson B; Calender A; Larsson C; Salmela P
Article: CANCER EPIDEMIOLOGY. 1998;22(6):544-548
A rapid method for DNA extraction from fine-needle aspiration biopsies of thyroid tumors, and subsequent RET mutation analysis
Zedenius J; Dwight T; Robinson BG; Delbridge L; Backdahl M; Wallin G; Larsson C; Weber G
Article: CANCER RESEARCH. 1997;57(21):4710-4713
Somatic deletions and mutations in the Cowden disease gene, PTEN, in sporadic thyroid tumors
Dahia PLM; Marsh DJ; Zheng ZM; Zedenius J; Komminoth P; Frisk T; Wallin G; Parsons R; Longy M; Larsson C; Eng C
Article: CANCER RESEARCH. 1997;57(3):500-503
Differential loss of heterozygosity in the region of the Cowden locus within 10q22-23 in follicular thyroid adenomas and carcinomas
Marsh DJ; Zheng ZM; Zedenius J; Kremer H; Padberg GW; Larsson C; Longy M; Eng C
Article: JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION. 1996;276(19):1575-1579
The relationship between specific RET proto-oncogene mutations and disease phenotype in multiple endocrine neoplasia type 2 - International RET mutation consortium analysis
Eng C; Clayton D; Schuffenecker I; Lenoir G; Cote G; Gagel RF; vanAmstel HKP; Lips CJM; Nishisho I; Takai SI; Marsh DJ; Robinson BG; FrankRaue K; Raue F; Xue FY; Noll WW; Romei C; Pacini F; Fink M; Niederle B; Zedenius J; Nordenskjold M; Komminoth P; Hendy GN; Gharib H; Thibodeau SN; Lacroix A; Frilling A; Ponder BAJ; Mulligan LM
Article: HUMAN GENETICS. 1996;97(3):299-303
Deletions of the long arm of chromosome 10 in progression of follicular thyroid tumors
Zedenius J; Wallin G; Svensson A; Bovee J; Hoog A; Backdahl M; Larsson C
Article: THYROID. 1996;6(1):1-9
Alterations of p53 and expression of WAF1/p21 in human thyroid tumors
Zedenius J; Larsson C; Wallin G; Backdahl M; Aspenblad U; Hoog A; Borresen AL; Auer G
Article: WORLD JOURNAL OF SURGERY. 1996;20(1):101-106
Stromal fibroblasts adjacent to invasive thyroid tumors: Expression of gelatinase a but not stromelysin 3 mRNA
Zedenius J; StahleBackdahl M; Enberg U; Grimelius L; Larsson C; Wallin G; Backdahl M
Journal article: JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM. 1995;80(10):3088-3090
MUTATIONS OF CODON-918 IN THE RET PROTOONCOGENE CORRELATE TO POOR-PROGNOSIS IN SPORADIC MEDULLARY-THYROID CARCINOMAS
ZEDENIUS J; LARSSON C; BERGHOLM U; BOVEE J; SVENSSON A; HALLENGREN B; GRIMELIUS L; BACKDAHL M; WEBER G; WALLIN G
Article: HUMAN GENETICS. 1995;96(1):27-32
ALLELOTYPING OF FOLLICULAR THYROID-TUMORS
ZEDENIUS J; WALLIN G; SVENSSON A; GRIMELIUS L; HOOG A; LUNDELL G; BACKDAHL M; LARSSON C
Journal article: HUMAN MOLECULAR GENETICS. 1994;3(10):1775-1781
THE PHOSPHOLIPASE-C BETA-3 GENE LOCATED IN THE MEN1 REGION SHOWS LOSS OF EXPRESSION IN ENDOCRINE TUMORS
WEBER G; FRIEDMAN E; GRIMMOND S; HAYWARD NK; PHELAN C; SKOGSEID B; GOBL A; ZEDENIUS J; SANDELIN K; TEH BT; CARSON E; WHITE I; OBERG K; SHEPHERD J; NORDENSKOLD M; LARSSON C
Journal article: HUMAN MOLECULAR GENETICS. 1994;3(8):1259-1262
SOMATIC AND MEN 2A DE-NOVO MUTATIONS IDENTIFIED IN THE RET PROTOONCOGENE BY SCREENING OF SPORADIC MTC-S
ZEDENIUS J; WALLIN G; HAMBERGER B; NORDENSKJOLD M; WEBER G; LARSSON C
Journal article: SURGERY. 1992;112(6):1154-1159
ADDITION OF NUCLEAR-DNA CONTENT TO THE AMES RISK-GROUP CLASSIFICATION FOR PAPILLARY THYROID-CANCER
PASIEKA JL; ZEDENIUS J; AUER G; GRIMELIUS L; HOOG A; LUNDELL G; WALLIN G; BACKDAHL M; IRVIN G; ROSEN I; PROYE C; MCLEOD M; GRANT C; HAY I
Journal article: WORLD JOURNAL OF SURGERY. 1992;16(4):589-594
FOLLICULAR TUMORS OF THE THYROID-GLAND - DIAGNOSIS, CLINICAL ASPECTS AND NUCLEAR-DNA ANALYSIS
ZEDENIUS J; AUER G; BACKDAHL M; FALKMER U; GRIMELIUS L; LUNDELL G; WALLIN G
Article: INTERNATIONAL JOURNAL OF ONCOLOGY. 1992;33(4):861-869
Gene-specific promoter hypermethylation without global hypomethylation in follicular thyroid cancer
Lee J-J; Geli J; Larsson C; Wallin G; Karimi M; Zedenius J; Hoog A; Foukakis T
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All other publications

Editorial comment: EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING. 2024;51(8):2165-2171
How nuclear imaging changed parathyroid surgical strategies through time
Schouw HM; Noltes ME; Brouwers AH; Nilsson I-L; Zedenius J; Kruijff S
Editorial comment: AMERICAN JOURNAL OF SURGERY. 2024;229:189-190
Trailblazing Women: Female Nobel laureates in medicine as role models
Zedenius J
Review: LAKARTIDNINGEN. 2024;121:23108
[Molecular diagnostics enable targeted therapies for anaplastic and poorly differentiated thyroid cancer].
Altena R; Nilsson M; Bergman V; Dahlberg J; Christofer Juhlin C; Zedenius J
Review: LAKARTIDNINGEN. 2023;120:23014
[Adrenohepatic fusion - an unknown but not uncommon phenomenon of clinical importance].
Stenman A; Zedenius J; Christofer Juhlin C
Preprint: RESEARCH SQUARE. 2023
5hmC immunohistochemistry: a predictor of TERT promoter mutational status in follicular thyroid carcinoma?
Hysek M; Hellgren S; Condello V; Larsson C; Zedenius J; Juhlin CC
Review: CANCERS. 2022;14(9):2210
Metastatic Neuroendocrine Neoplasms of Unknown Primary: Clues from Pathology Workup
Juhlin CC; Zedenius J; Hoog A
Conference publication: EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING. 2022;49(SUPPL 1):S440-S441
Preclinical evaluation of a promising novel, antibody-based ¹⁷⁷Lu-labeled radiopharmaceutical for potential use in advanced thyroid cancer
Mortensen A; Berglund H; Juhlin C; Stenman A; Jha P; Frejd F; Zedenius J; Nestor M
Review: HEAD AND NECK PATHOLOGY. 2021;15(2):668-675
Macrofollicular Variant of Follicular Thyroid Carcinoma (MV-FTC) with a SomaticDICER1Gene Mutation: Case Report and Review of the Literature
Hellgren LS; Hysek M; Jatta K; Zedenius J; Juhlin CC
Review: JOURNAL OF MEDICAL CASE REPORTS. 2020;14(1):44
Metastatic malignant melanoma with neuroendocrine differentiation: a case report and review of the literature
Juhlin CC; Zedenius J; Haglund F
Editorial comment: WORLD JOURNAL OF SURGERY. 2020;44(2):486-487
Invited Commentary: Use of Electrical Impedance Spectroscopy for Intraoperative Tissue Differentiation During Thyroid and Parathyroid Surgery
Zedenius J
Review: CANCERS. 2019;11(2):E225-225
The Value of Histological Algorithms to Predict the Malignancy Potential of Pheochromocytomas and Abdominal Paragangliomas-A Meta-Analysis and Systematic Review of the Literature
Stenman A; Zedenius J; Juhlin CC
Other: SAGE OPEN MEDICAL CASE REPORTS. 2019;7:2050313X19883770
Synchronous aldosterone- and cortisol-producing adrenocortical adenomas diagnosed using CYP11B immunohistochemistry
Stenman A; Shabo I; Ramstrom A; Zedenius J; Juhlin CC
Letter: ENDOCRINE PATHOLOGY. 2018;29(4):380-383
TERT Immunohistochemistry Is a Poor Predictor of TERT Promoter Mutations and Gene Expression in Follicular Thyroid Carcinoma
Paulsson JO; Olander A; Haglund F; Zedenius J; Juhlin CC
Letter: CLINICAL ENDOCRINOLOGY. 2018;88(2):343-345
Telomerase reverse transcriptase promoter hypermethylation is associated with metastatic disease in abdominal paraganglioma
Svahn F; Juhlin CC; Paulsson JO; Fotouhi O; Zedenius J; Larsson C; Stenman A
Conference publication: CANCER RESEARCH. 2015;75:3462
Proteomic profiling reveals novel targets for combination treatment with lanreotide in neuroendocrine tumors
Fotouhi O; Kjellin H; Hashemi J; Lu M; Juhlin C; Hoog A; Zedenius J; Larsson C; Lehtio J; Kjellman M
Conference publication: INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE. 2014;34:S94
Genetic and epigenetic mechanisms of small intestinal neuroendocrine tumors
Hashemi J; Fotouhi O; Sulaiman L; Kjellman M; Hoog A; Zedenius J; Larsson C
Meeting abstract: CANCER RESEARCH. 2013;73(8):5317
Evidence for intracellular calcium-regulated secretion in gastrointestinal stromal tumor.
Berglund E; Berglund D; Akcakaya P; Ghaderi M; Dare E; Berggren P-O; Aspinwall CA; Lui W-O; Zedenius J; Larsson C; Branstrom R
Conference publication: CANCER RESEARCH. 2012;72:1141
Telomerase activity in relation to RET mutation status in medullary thyroid carcinoma
Wang N; Zedenius J; Backdahl M; Larsson C
Conference publication: NEUROENDOCRINOLOGY. 2012;96:3
Alterations of Global and Gene-Specific DNA Methylation in Midgut Carcinoids
Fotouhi O; Hashemi J; Kjellman M; Hoog A; Zedenius J; Larsson C
Meeting abstract: JOURNAL OF CLINICAL ONCOLOGY. 2011;29(15):e20524
The relationship between outcome and side effects during imatinib treatment of advanced GIST
Ahlen J; Branstrom R; Zedenius J; Westerdahl J; Nilsson I
Meeting abstract: JOURNAL OF CLINICAL ONCOLOGY. 2011;29(15):e20503
Immediate action of imatinib mesylate on calcium signaling in gastrointestinal stromal tumors (GIST)
Berglund E; Lu M; Akcakaya P; Zedenius J; Nilsson I; Ahlen J; Lui W; Larsson C; Branstrom R
Conference publication: CANCER RESEARCH. 2011;71:4940
Microrna expression profiling in adrenocortical neoplasia: Implications on tumor size and functionality
Velazquez-Fernandez D; Caramuta S; Ozata DM; Akcakaya P; Hoog A; Hamberger B; Backdahl M; Larsson C; Zedenius J; Lui W-O
Meeting abstract: CANCER RESEARCH. 2010;70:lb-219-lb-219
Elevated expression of cellular proliferative index MIB-1 in post-Chornobyl papillary thyroid carcinoma with coexisting thyroiditis
Dinets A; Hulchiy M; Sofiadis A; Hoag A; Larsson C; Zedenius J
Review: LAKARTIDNINGEN. 2009;106(41):2607-2611
[Antithyroid drug-induced agranulocytosis. A rare but dreaded condition].
Lehtihet M; Zedenius J; Helldén A; Axelsson R; Calissendorff J
Conference publication: CANCER RESEARCH. 2009;69
Proteomic studies in well differentiated thyroid tumors
Sofiadis A; Zedenius J; Wallin G; Foukakis T; Hoog A; Orre L; Lehtio J; Larsson C
Editorial comment: NATURE CLINICAL PRACTICE ENDOCRINOLOGY AND METABOLISM. 2008;4(8):432-433
Is somatic RET mutation a prognostic factor for sporadic medullary thyroid carcinoma?
Zedenius J
Book chapter: CLINICAL ENDOCRINE ONCOLOGY. 2008;p. 124-129
Pathogenesis of Thyroid Cancer
Zedenius J; Foukakis T
Editorial comment: ACTA ONCOLOGICA. 2008;47(1):3-4
Novel therapeutic strategies for neuroendocrine tumours - can eminence replace evidence?
Zedenius J
Conference publication: HORMONE RESEARCH IN PAEDIATRICS. 2007;68:41
MIB-1 proliferation index in thyroid tumors' fine needle aspiration cytology (FNAC):: A prognostic tool?
Sofiadis A; Larsson C; Wallin G; Zedenius J; Foukakis T; Hoog A; Tani E; Kjellman P
Conference publication: AMERICAN JOURNAL OF HUMAN GENETICS. 2003;73(5):219
Cytogenetic characterization of thyroid tumors and cell lines using comparative genomic hybridization, spectral karyoyping and G-banding
Foukakis T; Thoppe SR; Lagercrantz S; Dwight T; Svensson A; Liu WO; Wallin G; Zedenius J; Larsson C
Published conference paper: BRITISH JOURNAL OF SURGERY. 2001;88(4):557-563
Expression of the RET proto-oncogene in papillary thyroid carcinoma and its correlation with clinical outcome
Kjellman P; Learoyd DL; Messina M; Weber G; Höög A; Wallin G; Larsson C; Robinson BG; Zedenius J
Conference publication: BRITISH JOURNAL OF SURGERY. 2000;87(9):1258-1259
Expression of the RET proto-oncogene and the RET/PTC oncogenes in papillary thyroid carcinomas and its correlation to clinical manifestations
Kjellman PC; Learoyd DL; Larsson C; Wallin G; Messina M; Robinson BG; Zedenius J
Letter: LANCET. 2000;356(9228):512-513
More parathyroidectomies? Perhaps not.
Nordenström J; Zedenius J
Review: WORLD JOURNAL OF SURGERY. 2000;24(8):923-933
Molecular genetics of thyroid tumors and surgical decision-making
Learoyd DL; Messina M; Zedenius J; Robinson BG
Editorial comment: SURGERY. 2000;128(6):957
The helix-loop-helix transcription factor, Id-1, is overexpressed in medullary thyroid cancer - Discussion
Zedenius J; Kebebew; Weber C
Published conference paper: WORLD JOURNAL OF SURGERY. 1998;22(7):725-730
Anaplastic giant cell carcinoma of the thyroid gland: Treatment and survival over a 25-year period
Nilsson O; Lindeberg J; Zedenius J; Ekman E; Tennvall J; Blomgren H; Grimelius L; Lundell G; Wallin G
Conference publication: AMERICAN JOURNAL OF HUMAN GENETICS. 1997;61(4):A63
Mutation and deletion analysis of the Cowden disease gene, PTEN, in sporadic nonmedullary thyroid tumors.
Dahla PLM; Marsh DJ; Zheng Z; Zedenius J; Komminoth P; Parsons R; Longy M; Larsson C; Eng C
Published conference paper: JOURNAL OF INTERNAL MEDICINE. 1995;238(4):343-346
GENOTYPE-PHENOTYPE CORRELATION IN MULTIPLE ENDOCRINE NEOPLASIA TYPE-2 - REPORT OF THE INTERNATIONAL-RET-MUTATION-CONSORTIUM
MULLIGAN LM; MARSH DJ; ROBINSON BG; SCHUFFENECKER L; ZEDENIUS J; LIPS CJM; GAGEL RF; TAKAI SL; NOLL WW; FINK M; RAUE F; LACROIX A; THIBODEAU SN; FRILLING A; PONDER BAJ; ENG C
Other: AMERICAN JOURNAL OF PATHOLOGY. 1995;146(5):1073-1078
DECREASED EXPRESSION OF RAS GTPASE-ACTIVATING PROTEIN IN HUMAN TROPHOBLASTIC TUMORS
STAHLEBACKDHAL M; INOUE M; ZEDENIUS J; SANDSTEDT B; DEMARCO L; FLAM F; SILFVERSWARD C; ANDRADE J; FRIEDMAN E
Conference publication: AMERICAN JOURNAL OF HUMAN GENETICS. 1995;57(4):225
DECREASED EXPRESSION OF RASGTPASE ACTIVATING PROTEIN (RASGAP) IN HUMAN TROPHOBLASTIC TUMORS
FRIEDMAN E; STAHLEBACKDHAL M; PELEG S; INOUE M; ZEDENIUS J; SANDSTEDT B; DEMARCO L; FLAM F; SILFVERSWARD C; ANDRADE J
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Professor, Senior, Department of Molecular Medicine and Surgery, Karolinska Institutet, 2024-2025
Professor/Senior Physician, Department of Molecular Medicine and Surgery, Karolinska Institutet, 2017-2024

Degrees and Education

Docent, Karolinska Institutet, 1999

Supervision

David Thorsteinsson, Primary hyperparathyroidism: genetic and environmental risk factors and comorbidities., 2021
Sophie Norenstedt, Primary hyperparathyroidism : comorbidity and outcome after parathyroid adenomectomy.

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