Jan Mulder

Publications
Public outreach and news

Articles

Article: MOLECULAR PSYCHIATRY. 2024;:1-11
Three cases with chronic obsessive compulsive disorder report gains in wellbeing and function following rituximab treatment
Gallwitz M; Lindqvist I; Mulder J; Rasmusson AJ; Larsson A; Husen E; Borin J; van der Spek PJ; Sabbagh N; Widgren A; Bergquist J; Cervenka S; Burman J; Cunningham JL
Article: GLIA. 2024;72(9):1590-1603
Characterization of reduced astrocyte creatine kinase levels in Alzheimer's disease
Zheng T; Kotol D; Sjoberg R; Mitsios N; Uhlen M; Zhong W; Edfors F; Mulder J
Article: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2024;78:54-63
Substance P, NPY, CCK and their receptors in five brain regions in major depressive disorder with transcriptomic analysis of locus coeruleus neurons
Barde S; Aguila J; Zhong W; Solarz A; Mei I; Prud'homme J; Palkovits M; Turecki G; Mulder J; Uhlen M; Nagy C; Mechawar N; Hedlund E; Hokfelt T
Article: EUROPEAN JOURNAL OF NEUROLOGY. 2023;30(10):3142-3148
Myoclonus in patients with COVID-19: Findings of autoantibodies against brain structures in cerebrospinal fluid
Lindqvist I; Cunningham JL; Mulder J; Feresiadou A; Rostami E; Virhammar J; Kumlien E
Article: CELL. 2023;186(17):3726-3743.e24
Single-cell spatial transcriptome reveals cell-type organization in the macaque cortex
Chen A; Sun Y; Lei Y; Li C; Liao S; Meng J; Bai Y; Liu Z; Liang Z; Zhu Z; Yuan N; Yang H; Wu Z; Lin F; Wang K; Li M; Zhang S; Yang M; Fei T; Zhuang Z; Huang Y; Zhang Y; Xu Y; Cui L; Zhang R; Han L; Sun X; Chen B; Li W; Huangfu B; Ma K; Ma J; Li Z; Lin Y; Wang H; Zhong Y; Zhang H; Yu Q; Wang Y; Liu X; Peng J; Liu C; Chen W; Pan W; An Y; Xia S; Lu Y; Wang M; Song X; Liu S; Wang Z; Gong C; Huang X; Yuan Y; Zhao Y; Chai Q; Tan X; Liu J; Zheng M; Li S; Huang Y; Hong Y; Huang Z; Li M; Jin M; Li Y; Zhang H; Sun S; Gao L; Bai Y; Cheng M; Hu G; Liu S; Wang B; Xiang B; Li S; Li H; Chen M; Wang S; Li M; Liu W; Liu X; Zhao Q; Lisby M; Wang J; Fang J; Lin Y; Xie Q; He J; Xu H; Huang W; Mulder J; Yang H; Sun Y; Uhlen M; Poo M; Wang J; Yao J; Wei W; Li Y; Shen Z; Liu L; Liu Z; Xu X; Li C
Article: SCIENTIFIC REPORTS. 2022;12(1):21817
A conserved MTMR lipid phosphatase increasingly suppresses autophagy in brain neurons during aging
Kovacs T; Szinyakovics J; Billes V; Muranyi G; Varga VB; Bjelik A; Legradi A; Szabo M; Sandor S; Kubinyi E; Szekeres-Paracky C; Szocsics P; Loke J; Mulder J; Gulyas B; Renner E; Palkovits M; Gulya K; Magloczky Z; Vellai T
Article: ACTA NEUROPATHOLOGICA. 2022;144(4):651-676
Spatiotemporal characterization of cellular tau pathology in the human locus coeruleus-pericoerulear complex by three-dimensional imaging
Gilvesy A; Husen E; Magloczky Z; Mihaly O; Hortobagyi T; Kanatani S; Heinsen H; Renier N; Hokfelt T; Mulder J; Uhlen M; Kovacs GG; Adori C
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2022;119(33):e2123146119
The neuropeptide landscape of human prefrontal cortex
Zhong W; Barde S; Mitsios N; Adori C; Oksvold P; von Feilitzen K; O'Learyd L; Csiba L; Hortobagyi T; Szocsics P; Mechawar N; Magloczky Z; Renner E; Palkovits M; Uhlen M; Mulder J; Hokfelt T
Article: NATURE COMMUNICATIONS. 2022;13(1):3620
Endothelial cell heterogeneity and microglia regulons revealed by a pig cell landscape at single-cell level
Wang F; Ding P; Liang X; Ding X; Brandt CB; Sjostedt E; Zhu J; Bolund S; Zhang L; de Rooij LPMH; Luo L; Wei Y; Zhao W; Lv Z; Hasko J; Li R; Qin Q; Jia Y; Wu W; Yuan Y; Pu M; Wang H; Wu A; Xie L; Liu P; Chen F; Herold J; Kalucka J; Karlsson M; Zhang X; Helmig RB; Fagerberg L; Lindskog C; Ponten F; Uhlen M; Bolund L; Jessen N; Jiang H; Xu X; Yang H; Carmeliet P; Mulder J; Chen D; Lin L; Luo Y
Article: CELL. 2022;185(10):1777-1792.e21
Spatiotemporal transcriptomic atlas of mouse organogenesis using DNA nanoball-patterned arrays
Chen A; Liao S; Cheng M; Ma K; Wu L; Lai Y; Qiu X; Yang J; Xu J; Hao S; Wang X; Lu H; Chen X; Liu X; Huang X; Li Z; Hong Y; Jiang Y; Peng J; Liu S; Shen M; Liu C; Li Q; Yuan Y; Wei X; Zheng H; Feng W; Wang Z; Liu Y; Wang Z; Yang Y; Xiang H; Han L; Qin B; Guo P; Lai G; Munoz-Canoves P; Maxwell PH; Thiery JP; Wu Q-F; Zhao F; Chen B; Li M; Dai X; Wang S; Kuang H; Hui J; Wang L; Fei J-F; Wang O; Wei X; Lu H; Wang B; Liu S; Gu Y; Ni M; Zhang W; Mu F; Yin Y; Yang H; Lisby M; Cornall RJ; Mulder J; Uhlen M; Esteban MA; Li Y; Liu L; Xu X; Wang J
Article: NATURE. 2022;604(7907):723-731
Cell transcriptomic atlas of the non-human primate Macaca fascicularis
Han L; Wei X; Liu C; Volpe G; Zhuang Z; Zou X; Wang Z; Pan T; Yuan Y; Zhang X; Fan P; Guo P; Lai Y; Lei Y; Liu X; Yu F; Shangguan S; Lai G; Deng Q; Liu Y; Wu L; Shi Q; Yu H; Huang Y; Cheng M; Xu J; Liu Y; Wang M; Wang C; Zhang Y; Xie D; Yang Y; Yu Y; Zheng H; Wei Y; Huang F; Lei J; Huang W; Zhu Z; Lu H; Wang B; Wei X; Chen F; Yang T; Du W; Chen J; Xu S; An J; Ward C; Wang Z; Pei Z; Wong C-W; Liu X; Zhang H; Liu M; Qin B; Schambach A; Isern J; Feng L; Liu Y; Guo X; Liu Z; Sun Q; Maxwell PH; Barker N; Munoz-Canoves P; Gu Y; Mulder J; Uhlen M; Tan T; Liu S; Yang H; Wang J; Hou Y; Xu X; Esteban MA; Liu L
Article: BMC BIOLOGY. 2022;20(1):25
Genome-wide annotation of protein-coding genes in pig
Karlsson M; Sjostedt E; Oksvold P; Sivertsson A; Huang J; Alvez MB; Arif M; Li X; Lin L; Yu J; Ma T; Xu F; Han P; Jiang H; Mardinoglu A; Zhang C; von Feilitzen K; Xu X; Wang J; Yang H; Bolund L; Zhong W; Fagerberg L; Lindskog C; Ponten F; Mulder J; Luo Y; Uhlen M
Article: NPJ PRECISION ONCOLOGY. 2021;5(1):97
FOXP3+ T cells in uterine sarcomas are associated with favorable prognosis, low extracellular matrix expression and reduced YAP activation
Gultekin O; Gonzalez-Molina J; Hardell E; Moyano-Galceran L; Mitsios N; Mulder J; Kokaraki G; Isaksson A; Sarhan D; Lehti K; Carlson JW
Article: SCIENCE ADVANCES. 2021;7(31):eabh2169
A single-cell type transcriptomics map of human tissues
Karlsson M; Zhang C; Mear L; Zhong W; Digre A; Katona B; Sjoestedt E; Butler L; Odeberg J; Dusart P; Edfors F; Oksvold P; von Feilitzen K; Zwahlen M; Arif M; Altay O; Li X; Ozcan M; Mardonoglu A; Fagerberg L; Mulder J; Luo Y; Ponten F; Uhlen M; Lindskog C
Article: SCIENCE ADVANCES. 2021;7(30):eabg5733
Disorganization and degeneration of liver sympathetic innervations in nonalcoholic fatty liver disease revealed by 3D imaging
Adori C; Daraio T; Kuiper R; Barde S; Horvathova L; Yoshitake T; Ihnatko R; Valladolid-Acebes I; Vercruysse P; Wellendorf AM; Gramignoli R; Bozoky B; Kehr J; Theodorsson E; Cancelas JA; Mravec B; Jorns C; Ellis E; Mulder J; Uhlen M; Bark C; Hokfelt T
Article: KNEE SURGERY, SPORTS TRAUMATOLOGY, ARTHROSCOPY. 2021;29(7):2228-2236
Increased levels of inflammatory markers in the subscapularis tendon and joint capsule in patients with subacromial impingement
Farfaras S; Roshani L; Mulder J; Mitsios N; Hallstrom EK; Kartus J-T
Article: COMMUNICATIONS BIOLOGY. 2021;4(1):717
A porcine brain-wide RNA editing landscape
Huang J; Lin L; Dong Z; Yang L; Zheng T; Gu W; Zhang Y; Yin T; Sjostedt E; Mulder J; Uhlen M; Kristiansen K; Bolund L; Luo Y
Article: ACTA NEUROPATHOLOGICA. 2021;141(5):681-696
Distinct amyloid-β and tau-associated microglia profiles in Alzheimer's disease
Gerrits E; Brouwer N; Kooistra SM; Woodbury ME; Vermeiren Y; Lambourne M; Mulder J; Kummer M; Moller T; Biber K; den Dunnen WFA; De Deyn PP; Eggen BJL; Boddeke EWGM
Article: JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM. 2021;41(3):617-629
The cellular basis of increased PET hypoxia tracer uptake in focal cerebral ischemia with comparison between [¹⁸F]FMISO and [⁶⁴Cu]CuATSM
Little PV; Arnberg F; Jussing E; Lu L; Jensen AI; Mitsios N; Mulder J; Tran TA; Holmin S
Article: TRANSLATIONAL PSYCHIATRY. 2020;10(1):401
Exploring autoantibody signatures in brain tissue from patients with severe mental illness
Just D; Manberg A; Mitsios N; Stockmeier CA; Rajkowska G; Uhlen M; Mulder J; Feuk L; Cunningham JL; Nilsson P; Carlstrom EL
Article: JOURNAL OF NEUROSCIENCE METHODS. 2020;339:108708
A manual multiplex immunofluorescence method for investigating neurodegenerative diseases
Ehrenberg AJ; Morales DO; Piergies AMH; Li SH; Tejedor JS; Mladinov M; Mulder J; Grinberg LT
Article: SCIENCE. 2020;367(6482):1090
An atlas of the protein-coding genes in the human, pig, and mouse brain
Sjostedt E; Zhong W; Fagerberg L; Karlsson M; Mitsios N; Adori C; Oksvold P; Edfors F; Limiszewska A; Hikmet F; Huang J; Du Y; Lin L; Dong Z; Yang L; Liu X; Jiang H; Xu X; Wang J; Yang H; Bolund L; Mardinoglu A; Zhang C; von Feilitzen K; Lindskog C; Ponten F; Luo Y; Hokfelt T; Uhlen M; Mulder J
Article: SCIENTIFIC REPORTS. 2020;10(1):1880
Expression and regulation of FRMD6 in mouse DRG neurons and spinal cord after nerve injury
Lyu C; Lyu G-W; Mulder J; Uhlen M; Cai X-H; Hokfelt T; Shi T-JS
Article: EMBO JOURNAL. 2020;39(1):e100882
Life-long impairment of glucose homeostasis upon prenatal exposure to psychostimulants
Korchynska S; Krassnitzer M; Malenczyk K; Prasad RB; Tretiakov EO; Rehman S; Cinquina V; Gernedl V; Farlik M; Petersen J; Hannes S; Schachenhofer J; Reisinger SN; Zambon A; Asplund O; Artner I; Keimpema E; Lubec G; Mulder J; Bock C; Pollak DD; Romanov RA; Pifl C; Groop L; Hoekfelt TGM; Harkany T
Article: JOURNAL OF PAIN RESEARCH. 2020;13:419-429
G Protein-Gated Inwardly Rectifying Potassium Channel Subunit 3 is Upregulated in Rat DRGs and Spinal Cord After Peripheral Nerve Injury
Lyu C; Lyu G-W; Mulder J; Martinez A; Shi T-JS
Article: SCIENCE. 2019;366(6472):eaax9198
A genome-wide transcriptomic analysis of protein-coding genes in human blood cells
Uhlen M; Karlsson MJ; Zhong W; Tebani A; Pou C; Mikes J; Lakshmikanth T; Forsstrom B; Edfors F; Odeberg J; Mardinoglu A; Zhang C; von Feilitzen K; Mulder J; Sjostedt E; Hober A; Oksvold P; Zwahlen M; Ponten F; Lindskog C; Sivertsson A; Fagerberg L; Brodin P
Article: SCIENCE SIGNALING. 2019;12(609):eaaz0274
The human secretome
Uhlen M; Karlsson MJ; Hober A; Svensson A-S; Scheffel J; Kotol D; Zhong W; Tebani A; Strandberg L; Edfors F; Sjostedt E; Mulder J; Mardinoglu A; Berling A; Ekblad S; Dannemeyer M; Kanje S; Rockberg J; Lundqvist M; Malm M; Volk A-L; Nilsson P; Manberg A; Dodig-Crnkovic T; Pin E; Zwahlen M; Oksvold P; von Feilitzen K; Haussler RS; Hong M-G; Lindskog C; Ponten F; Katona B; Vuu J; Lindstrom E; Nielsen J; Robinson J; Ayoglu B; Mahdessian D; Sullivan D; Thul P; Danielsson F; Stadler C; Lundberg E; Bergstrom G; Gummesson A; Voldborg BG; Tegel H; Hober S; Forsstrom B; Schwenk JM; Fagerberg L; Sivertsson A
Article: JOURNAL OF THE NATIONAL CANCER INSTITUTE. 2019;111(9):983-995
Impact of Epithelial-Stromal Interactions on Peritumoral Fibroblasts in Ductal Carcinoma in Situ
Strell C; Paulsson J; Jin S-B; Tobin NP; Mezheyeuski A; Roswall P; Mutgan C; Mitsios N; Johansson H; Wickberg SM; Svedlund J; Nilsson M; Hall P; Mulder J; Radisky DC; Pietras K; Bergh J; Lendahl U; Warnberg F; Ostman A
Article: BRAIN RESEARCH. 2019;1711:140-145
In vitro phosphodiesterase 10A (PDE10A) binding in whole hemisphere human brain using the PET radioligand [¹⁸F]MNI-659
Svedberg MM; Varnas K; Varrone A; Mitsios N; Mulder J; Gulyas B; Beaumont V; Munoz-Sanjuan I; Zaleska MM; Schmidt CJ; Halldin C; Mrzljak L
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2018;293(48):18477-18493
Dishevelled enables casein kinase 1-mediated phosphorylation of Frizzled 6 required for cell membrane localization
Strakova K; Kowalski-Jahn M; Gybel T; Valnohova J; Dhople VM; Harnos J; Bernatik O; Ganji RS; Zdrahal Z; Mulder J; Lindskog C; Bryja V; Schulte G
Article: CEREBRAL CORTEX. 2018;28(9):3129-3142
Neuronal Expression of Opioid Gene is Controlled by Dual Epigenetic and Transcriptional Mechanism in Human Brain
Bazov I; Sarkisyan D; Kononenko O; Watanabe H; Taqi MM; Stalhandske L; Verbeek DS; Mulder J; Rajkowska G; Sheedy D; Kril J; Sun X; Syvanen A-C; Yakovleva T; Bakalkin G
Article: JOURNAL OF CLINICAL INVESTIGATION. 2018;128(9):3757-3768
Ca²⁺- binding protein NECAB2 facilitates inflammatory pain hypersensitivity
Zhang M-D; Su J; Adori C; Cinquina V; Malenczyk K; Girach F; Peng C; Ernfors P; Low P; Borgius L; Kiehn O; Watanabe M; Uhlen M; Mitsios N; Mulder J; Harkany T; Hokfelt T
Article: EPILEPSIA. 2018;59(8):1507-1517
The expression of inflammatory markers and their potential influence on efflux transporters in drug-resistant mesial temporal lobe epilepsy tissue
Weidner LD; Kannan P; Mitsios N; Kang SJ; Hall MD; Theodore WH; Innis RB; Mulder J
Article: EMBO JOURNAL. 2017;36(14):2107-2125
A TRPV1-to-secretagogin regulatory axis controls pancreatic β-cell survival by modulating protein turnover
Malenczyk K; Girach F; Szodorai E; Storm P; Segerstolpe A; Tortoriello G; Schnell R; Mulder J; Romanov RA; Borok E; Piscitelli F; Di Marzo V; Szabo G; Sandberg R; Kubicek S; Lubec G; Hokfelt T; Wagner L; Groop L; Harkany T
Article: JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM. 2017;37(6):2062-2075
An automated method measures variability in P-glycoprotein and ABCG2 densities across brain regions and brain matter
Kannan P; Schain M; Kretzschmar WW; Weidner L; Mitsios N; Gulyas B; Blom H; Gottesman MM; Innis RB; Hall MD; Mulder J
Article: CEREBRAL CORTEX. 2017;27(6):3360-3377
Injury Leads to the Appearance of Cells with Characteristics of Both Microglia and Astrocytes in Mouse and Human Brain
Wilhelmsson U; Andersson D; De Pablo Y; Pekny R; Stahlberg A; Mulder J; Mitsios N; Hortobagyi T; Pekny M; Pekna M
Article: SCIENCE. 2017;356(6340):eaal3321
A subcellular map of the human proteome
Thul PJ; Akesson L; Wiking M; Mahdessian D; Geladaki A; Blal HA; Alm T; Asplund A; Bjork L; Breckels LM; Backstrom A; Danielsson F; Fagerberg L; Fall J; Gatto L; Gnann C; Hober S; Hjelmare M; Johansson F; Lee S; Lindskog C; Mulder J; Mulvey CM; Nilsson P; Oksvold P; Rockberg J; Schutten R; Schwenk JM; Sivertsson A; Sjostedt E; Skogs M; Stadler C; Sullivan DP; Tegel H; Winsnes C; Zhang C; Zwahlen M; Mardinoglu A; Ponten F; von Feilitzen K; Lilley KS; Uhlen M; Lundberg E
Article: CELLULAR SIGNALLING. 2017;32:93-103
FZD₁₀-Gα₁₃ signalling axis points to a role of FZD₁₀ in CNS angiogenesis
Hot B; Valnohova J; Arthofer E; Simon K; Shin J; Uhlen M; Kostenis E; Mulder J; Schulte G
Article: NUCLEAR MEDICINE AND BIOLOGY. 2017;46:50-53
Development of [¹¹C]/[³H-1]THK-5351-A potential novel carbon-11 tau imaging PET radioligand
Stepanov V; Svedberg M; Jia Z; Krasikova R; Lemoine L; Okamura N; Furumoto S; Mitsios N; Mulder J; Langstrom B; Nordberg A; Halldin C
Article: NATURE NEUROSCIENCE. 2017;20(2):176-188
Molecular interrogation of hypothalamic organization reveals distinct dopamine neuronal subtypes
Romanov RA; Zeisel A; Bakker J; Girach F; Hellysaz A; Tomer R; Alpar A; Mulder J; Clotman F; Keimpema E; Hsueh B; Crow AK; Martens H; Schwindling C; Calvigioni D; Bains JS; Mate Z; Szabo G; Yanagawa Y; Zhang M-D; Rendeiro A; Farlik M; Uhlen M; Wulff P; Bock C; Broberger C; Deisseroth K; Hokfelt T; Linnarsson S; Horvath TL; Harkany T
Article: BIOCHIMICA ET BIOPHYSICA ACTA - GENERAL SUBJECTS. 2017;1861(2):246-255
Opioid precursor protein isoform is targeted to the cell nuclei in the human brain
Kononenko O; Bazov I; Watanabe H; Gerashchenko G; Dyachok O; Verbeek DS; Alkass K; Druid H; Andersson M; Mulder J; Svenningsen AF; Rajkowska G; Stockmeier CA; Krishtal O; Yakovleva T; Bakalkin G
Article: PROTEOMICS - CLINICAL APPLICATIONS. 2016;10(12):1242-1253
CSF profiling of the human brain enriched proteome reveals associations of neuromodulin and neurogranin to Alzheimer's disease
Remnestal J; Just D; Mitsios N; Fredolini C; Mulder J; Schwenk JM; Uhlen M; Kultima K; Ingelsson M; Kilander L; Lannfelt L; Svenningsson P; Nellgard B; Zetterberg H; Blennow K; Nilsson P; Haggmark-Manberg A
Article: PROTEOMICS. 2016;16(22):2911-2920
Mass spectrometric analysis of synaptosomal membrane preparations for the determination of brain receptors, transporters and channels
Sialana FJ; Gulyassy P; Majek P; Sjostedt E; Kis V; Muller AC; Rudashevskaya EL; Mulder J; Bennett KL; Lubec G
Article: BRAIN STRUCTURE AND FUNCTION. 2016;221(7):3803-3823
Comparative anatomical distribution of neuronal calcium-binding protein (NECAB) 1 and-2 in rodent and human spinal cord
Zhang M-D; Barde S; Szodorai E; Josephson A; Mitsios N; Watanabe M; Attems J; Lubec G; Kovacs GG; Uhlen M; Mulder J; Harkany T; Hokfelt T
Article: ONCOTARGET. 2016;7(27):41948-41958
Survival-associated heterogeneity of marker-defined perivascular cells in colorectal cancer
Mezheyeuski A; Lindh MB; Guren TK; Dragomir A; Pfeiffer P; Kure EH; Ikdahl T; Skovlund E; Corvigno S; Strell C; Pietras K; Ponten F; Mulder J; Qvortrup C; Portyanko A; Tveit KM; Glimelius B; Sorbye H; Ostman A
Article: SCIENCE. 2016;353(6294):78-82
Visualization and analysis of gene expression in tissue sections by spatial transcriptomics
Stahl PL; Salmen F; Vickovic S; Lundmark A; Navarro JF; Magnusson J; Giacomello S; Asp M; Westholm JO; Huss M; Mollbrink A; Linnarsson S; Codeluppi S; Borg A; Ponten F; Costea PI; Sahlen P; Mulder J; Bergmann O; Lundeberg J; Frisen J
Article: BRAIN STRUCTURE AND FUNCTION. 2016;221(3):1279-1290
Acute neuroinflammation in a clinically relevant focal cortical ischemic stroke model in rat: longitudinal positron emission tomography and immunofluorescent tracking
Toth M; Little P; Arnberg F; Haggkvist J; Mulder J; Halldin C; Gulyas B; Holmin S
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2016;113(8):2188-2193
Anoctamin 2 identified as an autoimmune target in multiple sclerosis
Ayoglu B; Mitsios N; Kockum I; Khademi M; Zandian A; Sjoberg R; Forsstrom B; Bredenberg J; Bomfim IL; Holmgren E; Gronlund H; Guerreiro-Cacais AO; Abdelmagid N; Uhlen M; Waterboer T; Alfredsson L; Mulder J; Schwenk JM; Olsson T; Nilsson P
Article: DRUG METABOLISM AND DISPOSITION. 2016;44(2):275-282
Tariquidar Is an Inhibitor and Not a Substrate of Human and Mouse P-glycoprotein
Weidner LD; Fung KL; Kannan P; Moen JK; Kumar JS; Mulder J; Innis RB; Gottesman MM; Hall MD
Article: FRONTIERS IN NEUROLOGY. 2016;7:23
Lesion Size Is Exacerbated in Hypoxic Rats Whereas Hypoxia-Inducible Factor-1 Alpha and Vascular Endothelial Growth Factor Increase in Injured Normoxic Rats: A Prospective Cohort Study of Secondary Hypoxia in Focal Traumatic Brain Injury
Thelin EP; Frostell A; Mulder J; Mitsios N; Damberg P; Aski SN; Risling M; Svensson M; Morganti-Kossmann MC; Bellander B-M
Article: EXPERIMENTAL CELL RESEARCH. 2015;339(2):280-288
High levels of WNT-5A in human glioma correlate with increased presence of tumor-associated microglia/monocytes
Dijksterhuis JP; Arthofer E; Marinescu VD; Nelander S; Uhlen M; Ponten F; Mulder J; Schulte G
Article: JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS. 2015;354(3):384-393
The Inhibitor Ko143 Is Not Specific for ABCG2
Weidner LD; Zoghbi SS; Lu S; Shukla S; Ambudkar SV; Pike VW; Mulder J; Gottesman MM; Innis RB; Hall MD
Article: MOLECULAR PAIN. 2015;11:44
G protein-gated inwardly rectifying potassium channel subunits 1 and 2 are down-regulated in rat dorsal root ganglion neurons and spinal cord after peripheral axotomy
Lyu C; Mulder J; Barde S; Sahlholm K; Zeberg H; Nilsson J; Arhem P; Hokfelt T; Fried K; Shi T-JS
Article: ACTA NEUROPATHOLOGICA. 2015;129(4):541-563
Critical role of somatostatin receptor 2 in the vulnerability of the central noradrenergic system: new aspects on Alzheimer's disease
Adori C; Glueck L; Barde S; Yoshitake T; Kovacs GG; Mulder J; Magloczky Z; Havas L; Boelcskei K; Mitsios N; Uhlen M; Szolcsanyi J; Kehr J; Ronnback A; Schwartz T; Rehfeld JF; Harkany T; Palkovits M; Schulz S; Hokfelt T
Article: STROKE. 2015;46(3):835-842
Imaging of a Clinically Relevant Stroke Model Glucose Hypermetabolism Revisited
Arnberg F; Grafstrom J; Lundberg J; Nikkhou-Aski S; Little P; Damberg P; Mitsios N; Mulder J; Lu L; Soderman M; Stone-Elander S; Holmin S
Article: SCIENCE. 2015;347(6220):1260419
Tissue-based map of the human proteome
Uhlen M; Fagerberg L; Hallstroem BM; Lindskog C; Oksvold P; Mardinoglu A; Sivertsson A; Kampf C; Sjoestedt E; Asplund A; Olsson I; Edlund K; Lundberg E; Navani S; Szigyarto CA-K; Odeberg J; Djureinovic D; Takanen JO; Hober S; Alm T; Edqvist P-H; Berling H; Tegel H; Mulder J; Rockberg J; Nilsson P; Schwenk JM; Hamsten M; von Feilitzen K; Forsberg M; Persson L; Johansson F; Zwahlen M; von Heijne G; Nielsen J; Ponten F
Article: EMBO JOURNAL. 2015;34(1):36-54
A secretagogin locus of the mammalian hypothalamus controls stress hormone release
Romanov RA; Alpar A; Zhang M-D; Zeisel A; Calas A; Landry M; Fuszard M; Shirran SL; Schnell R; Dobolyi A; Olah M; Spence L; Mulder J; Martens H; Palkovits M; Uhlen M; Sitte HH; Botting CH; Wagner L; Linnarsson S; Hokfelt T; Harkany T
Article: PLOS ONE. 2015;10(6):e0130028
Defining the Human Brain Proteome Using Transcriptomics and Antibody-Based Profiling with a Focus on the Cerebral Cortex
Sjostedt E; Fagerberg L; Hallstrom BM; Haggmark A; Mitsios N; Nilsson P; Ponten F; Hokfelt T; Uhlen M; Mulder J
Article: EJNMMI RESEARCH. 2014;4(1):34
Evaluation of efficacy of a new MEK inhibitor, RO4987655, in human tumor xenografts by [¹⁸F] FDG-PET imaging combined with proteomic approaches
Tegnebratt T; Ruge E; Bader S; Ishii N; Aida S; Yoshimura Y; Ooi C-H; Lu L; Mitsios N; Meresse V; Mulder J; Pawlak M; Venturi M; Tessier J; Stone-Elander S
Article: CEREBRAL CORTEX. 2014;24(12):3277-3288
GABAergic Terminals Are a Source of Galanin to Modulate Cholinergic Neuron Development in the Neonatal Forebrain
Keimpema E; Zheng K; Barde SS; Berghuis P; Dobszay MB; Schnell R; Mulder J; Luiten PGM; Xu ZD; Runesson J; Langel U; Lu B; Hokfelt T; Harkany T
Article: JOURNAL OF PROTEOME RESEARCH. 2014;13(11):4607-4619
Affinity Proteomic Profiling of Plasma, Cerebrospinal Fluid, and Brain Tissue within Multiple Sclerosis
Bystrom S; Ayoglu B; Haggmark A; Mitsios N; Hong M-G; Drobin K; Forsstrom B; Fredolini C; Khademi M; Amor S; Uhlen M; Olsson T; Mulder J; Nilsson P; Schwenk JM
Article: EJNMMI RESEARCH. 2014;4(1):17
Visualization of angiogenesis during cancer development in the polyoma middle T breast cancer model: molecular imaging with (R)-[¹¹C]PAQ
Samen E; Lu L; Mulder J; Thorell J-O; Damberg P; Tegnebratt T; Holmgren L; Rundqvist H; Stone-Elander S
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2014;111(12):E1149-E1158
Neuronal calcium-binding proteins 1/2 localize to dorsal root ganglia and excitatory spinal neurons and are regulated by nerve injury
Zhang M-D; Tortoriello G; Hsueh B; Tomer R; Ye L; Mitsios N; Borgius L; Grant G; Kiehn O; Watanabe M; Uhlen M; Mulder J; Deisseroth K; Harkany T; Hokfelt TGM
Article: CIRCULATION: HEART FAILURE. 2014;7(2):359-366
Molecular- and Organelle-Based Predictive Paradigm Underlying Recovery by Left Ventricular Assist Device Support
Liem DA; Nsair A; Setty SP; Cadeiras M; Wang D; Maclellan R; Lotz C; Lin AJ; Tabaraki J; Li H; Ge J; Odeberg J; Ponten F; Larson E; Mulder J; Lundberg E; Weiss JN; Uhlen M; Ping P; Deng MC
Article: MOLECULAR & CELLULAR PROTEOMICS. 2014;13(2):397-406
Analysis of the human tissue-specific expression by genome-wide integration of transcriptomics and antibody-based proteomics.
Fagerberg L; Hallström BM; Oksvold P; Kampf C; Djureinovic D; Odeberg J; Habuka M; Tahmasebpoor S; Danielsson A; Edlund K; Asplund A; Sjöstedt E; Lundberg E; Szigyarto CA-K; Skogs M; Takanen JO; Berling H; Tegel H; Mulder J; Nilsson P; Schwenk JM; Lindskog C; Danielsson F; Mardinoglu A; Sivertsson A; von Feilitzen K; Forsberg M; Zwahlen M; Olsson I; Navani S; Huss M; Nielsen J; Ponten F; Uhlén M
Article: JOURNAL OF PROTEOME RESEARCH. 2013;12(6):2439-2448
Contribution of Antibody-based Protein Profiling to the Human Chromosome-centric Proteome Project (C-HPP)
Fagerberg L; Oksvold P; Skogs M; Algenas C; Lundberg E; Ponten F; Sivertsson A; Odeberg J; Klevebring D; Kampf C; Asplund A; Sjostedt E; Szigyarto CA-K; Edqvist P-H; Olsson I; Rydberg U; Hudson P; Takanen JO; Berling H; Bjorling L; Tegel H; Rockberg J; Nilsson P; Navani S; Jirstrom K; Mulder J; Schwenk JM; Zwahlen M; Hober S; Forsberg M; von Feilitzen K; Uhlen M
Article: AMERICAN JOURNAL OF PHYSIOLOGY. REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY. 2013;304(8):R675-R682
Renal sensory and sympathetic nerves reinnervate the kidney in a similar time-dependent fashion after renal denervation in rats
Mulder J; Hokfelt T; Knuepfer MM; Kopp UC
Article: MOLECULAR PAIN. 2012;8:80
Secretagogin is expressed in sensory CGRP neurons and in spinal cord of mouse and complements other calcium-binding proteins, with a note on rat and human
Shi T-JS; Xiang Q; Zhang M-D; Tortoriello G; Hammarberg H; Mulder J; Fried K; Wagner L; Josephson A; Uhlen M; Harkany T; Hokfelt T
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2011;108(44):18108-18113
Hypothalamic mitochondrial dysfunction associated with anorexia in the anx/anx mouse
Lindfors C; Nilsson IAK; Garcia-Roves PM; Zuberi AR; Karimi M; Donahue LR; Roopenian DC; Mulder J; Uhlen M; Ekstrom TJ; Davisson MT; Hokfelt TGM; Schalling M; Johansen JE
Article: JOURNAL OF COMPARATIVE NEUROLOGY. 2011;519(7):1219-1257
Characterization of NPY Y2 Receptor Protein Expression in the Mouse Brain. II. Coexistence with NPY, the Y1 Receptor, and Other Neurotransmitter-Related Molecules
Stanic D; Mulder J; Watanabe M; Hokfelt T
Article: BRAIN. 2011;134(Pt 4):1041-1060
Molecular reorganization of endocannabinoid signalling in Alzheimer's disease
Mulder J; Zilberter M; Pasquare SJ; Alpar A; Schulte G; Ferreira SG; Koefalvi A; Martin-Moreno AM; Keimpema E; Tanila H; Watanabe M; Mackie K; Hortobagyi T; de Ceballos ML; Harkany T
Article: GLIA. 2011;59(1):119-131
WNT Signaling in Activated Microglia Is Proinflammatory
Halleskog C; Mulder J; Dahlstrom J; Mackie K; Hortobagyi T; Tanila H; Puli LK; Faerber K; Harkany T; Schulte G
Article: SCIENCE SIGNALING. 2010;3(131):ra54
Increased Abundance of Opioid Receptor Heteromers After Chronic Morphine Administration
Gupta A; Mulder J; Gomes I; Rozenfeld R; Bushlin I; Ong E; Lim M; Maillet E; Junek M; Cahill CM; Harkany T; Devi LA
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2009;106(52):22492-22497
Secretagogin is a Ca²⁺-binding protein specifying subpopulations of telencephalic neurons
Mulder J; Zilberter M; Spence L; Tortoriello G; Uhlen M; Yanagawa Y; Aujard F; Hokfelt T; Harkany T
Article: JOURNAL OF NEUROCHEMISTRY. 2009;110(4):1330-1338
GABA action in immature neocortical neurons directly depends on the availability of ketone bodies
Rheims S; Holmgren CD; Chazal G; Mulder J; Harkany T; Zilberter T; Zilberter Y
Article: MOLECULAR & CELLULAR PROTEOMICS. 2009;8(7):1612-1622
Tissue Profiling of the Mammalian Central Nervous System Using Human Antibody-based Proteomics
Mulder J; Bjorling E; Jonasson K; Wernerus H; Hober S; Hokfelt T; Uhlen M
Article: NEUROSIGNALS. 2009;17(3):203-212
Expression of p-Akt in Sensory Neurons and Spinal Cord after Peripheral Nerve Injury
Shi T-JS; Huang P; Mulder J; Ceccatelli S; Hokfelt T
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2008;105(25):8760-8765
Endocannabinoid signaling controls pyramidal cell specification and long-range axon patterning
Mulder J; Aguado T; Keimpema E; Barabas K; Rosado CJB; Nguyen L; Monory K; Marsicano G; Di Marzo V; Hurd YL; Guillemot F; Mackie K; Lutz B; Guzman M; Lu H-C; Galve-Roperh I; Harkany T
Article: AMERICAN JOURNAL OF PHYSIOLOGY. REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY. 2007;293(4):R1561-R1572
Renal sympathetic nerve activity modulates afferent renal nerve activity by PGE₂-dependent activation of α₁- and α₂-adrenoceptors on renal sensory nerve fibers
Kopp UC; Cicha MZ; Smith LA; Mulder J; Hokfelt T
Article: MOLECULAR ENDOCRINOLOGY. 2007;21(7):1685-1698
GPR39 splice variants versus antisense gene LYPD1:: Expression and regulation in gastrointestinal tract, endocrine pancreas, liver, and white adipose tissue
Egerod KL; Holst B; Petersen PS; Hansen JB; Mulder J; Hokfelt T; Schwartz TW
Article: NEUROSCIENCE. 2007;146(4):1689-1703
Systematically generated antibodies against human gene products:: High throughput screening on sections from the rat nervous system
Mulder J; Wernerus H; Shi T-J; Ponten F; Hober S; Uhlen M; Hokfelt T
Article: SCIENCE. 2007;316(5828):1212-1216
Hardwiring the brain:: Endocannabinoids shape neuronal connectivity
Berghuis P; Rajnicek AM; Morozov YM; Ross RA; Mulder J; Urban GM; Monory K; Marsicano G; Matteoli M; Canty A; Irving AJ; Katona I; Yanagawa Y; Rakic P; Lutz B; Mackie K; Harkany T
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2007;104(3):949-954
Pituitary autoantibodies in autoimmune polyendocrine syndrome type 1
Bensing S; Fetissov SO; Mulder J; Perheentupa J; Gustafsson J; Husebye ES; Oscarson M; Ekwall O; Crock PA; Hokfelt T; Hulting A-L; Kampe O
Article: EUROPEAN JOURNAL OF NEUROSCIENCE. 2006;23(4):1063-1070
Vesicular glutamate transporter 3 (VGLUT3) identifies spatially segregated excitatory terminals in the rat substantia nigra
Martín-Ibañez R; Jenstad M; Berghuis P; Edwards RH; Hioki H; Kaneko T; Mulder J; Canals JM; Ernfors P; Chaudhry FA; Harkany T
Article: BRAIN RESEARCH BULLETIN. 2005;67(1-2):117-125
Input from the medial septum regulates adult hippocampal neurogenesis
Van der Borght K; Mulder J; Keijser JN; Eggen BJL; Luiten PGM; Van der Zee EA
Article: BEHAVIOURAL BRAIN RESEARCH. 2005;163(1):33-41
Galantamine-induced behavioral recovery after sublethal excitotoxic lesions to the rat medial septum
Mulder J; Harkany T; Czollner K; Cremers TIFH; Keijser JN; Nyakas C; Luiten PGM
Article: AMINO ACIDS. 2005;28(4):377-387
Regional distribution of biogenic amines, amino acids and cholinergic markers in the CNS of the C57BL/6 strain
Van Dam D; Marescau B; Cremers T; Mulder J; Engelborghs S; De Deyn PP
Article: NEUROCHEMISTRY INTERNATIONAL. 2005;46(5):409-422
Analysis of cholinergic markers, biogenic amines, and amino acids in the CNS of two APP overexpression mouse models
Van Dam D; Marescau B; Engelborghs S; Cremers T; Mulder J; Staufenbiel M; De Deyn PP
Article: DEVELOPMENTAL NEUROBIOLOGY. 2004;60(4):463-472
Neonatal handling increases sensitivity to acute neurodegeneration in adult rats
Horvath KM; Harkany T; Mulder J; Koolhaas JM; Luiten PGM; Meerlo P
Article: JOURNAL OF NEUROENDOCRINOLOGY. 2003;15(5):498-507
Chronic excess of corticosterone increases serotonergic fibre degeneration in aged rats
Nyakas C; Mulder J; Felszeghy K; Keijser JN; Mehra R; Luiten PGM
Article: NEUROREPORT. 2002;13(6):767-772
Distinct subsets of nucleus basalis neurons exhibit similar sensitivity to excitotoxicity
Harkany T; Varga C; Grosche J; Mulder J; Luiten PGM; Hortobágyi T; Penke B; Härtig W
Article: NEUROSCIENCE. 2002;110(3):489-504
17β-estradiol enhances cortical cholinergic innervation and preserves synaptic density following excitotoxic lesions to the rat nucleus basalis magnocellularis
Horvath KM; Hårtig W; Van der Veen R; Keijser JN; Mulder J; Ziegert M; Van der Zee EA; Harkany T; Luiten PGM
Article: NEUROREPORT. 2001;12(17):3767-3772
Cortical cholinergic decline parallels the progression of Borna virus encephalitis
Gies U; Görcs TJ; Mulder J; Planz O; Stitz L; Bilzer T; Luiten PGM; Harkany T
Article: NEUROSCIENCE. 2001;108(4):629-642
Oral post-lesion administration of 5-HT_1A receptor agonist repinotan hydrochloride (Bay X 3702) attenuates NMDA-induced delayed neuronal death in rat magnocellular nucleus basalis
Harkany T; Mulder J; Horvath KM; Keijser J; Van der Meeberg EK; Nyakas C; Luiten PGM
Article: NEUROSCIENCE. 2001;108(4):611-627
Short-term consequences of N-methyl-D-aspartate excitotoxicity in rat magnocellular nucleus basalis:: Effects on in vivo labelling of cholinergic neurons
Harkany T; Grosche J; Mulder J; Horvath KM; Keijser J; Hortobágyi T; Luiten PGM; Härtig W
Article: NEUROBIOLOGY OF DISEASE. 1999;6(2):109-121
N-methyl-D-aspartate receptor antagonist MK-801 and radical scavengers protect cholinergic nucleus basalis neurons against β-amyloid neurotoxicity
Harkany T; Mulder J; Sasvári M; Abrahám I; Kónya C; Zarándi M; Penke B; Luiten PGM; Nyakas C
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Review: CELL. 2024;187(17):4488-4519
Spatiotemporal omics for biology and medicine
Liu L; Chen A; Li Y; Mulder J; Heyn H; Xu X
Corrigendum: NATURE COMMUNICATIONS. 2022;13(1):6748
Endothelial cell heterogeneity and microglia regulons revealed by a pig cell landscape at single-cell level (vol 13, 3620, 2022)
Wang F; Ding P; Liang X; Ding X; Brandt CB; Sjostedt E; Zhu J; Bolund S; Zhang L; de Rooij LPMH; Luo L; Wei Y; Zhao W; Lv Z; Hasko J; Li R; Qin Q; Jia Y; Wu W; Yuan Y; Pu M; Wang H; Wu A; Xie L; Liu P; Chen F; Herold J; Kalucka J; Karlsson M; Zhang X; Helmig RB; Fagerberg L; Lindskog C; Ponten F; Uhlen M; Bolund L; Jessen N; Jiang H; Xu X; Yang H; Carmeliet P; Mulder J; Chen D; Lin L; Luo Y
Editorial comment: AMERICAN JOURNAL OF PSYCHIATRY. 2021;178(6):485-489
Autoimmune Encephalitis Presenting With Malignant Catatonia in a 40-Year-Old Male Patient With COVID-19
Mulder J; Feresiadou A; Fallmar D; Frithiof R; Virhammar J; Rasmusson A; Rostami E; Kumlien E; Cunningham JL
Letter: BRAIN, BEHAVIOR, AND IMMUNITY. 2021;94:473-474
Indirect immunofluorescence for detecting anti-neuronal autoimmunity in CSF after COVID-19-Possibilities and pitfalls
Mulder J; Lindqvist I; Rasmussoe AJ; Husen E; Ronnelid J; Kumlien E; Rostami E; Virhammar J; Cunningham JL
Review: ESMO OPEN. 2020;5(4):e000856
Combinations in the first-line treatment of patients with advanced/metastatic renal cell cancer: regulatory aspects
Moscetti L; Hennik P; Bolstad B; Camarero J; Josephson F; Melchiorri D; Gronvold MS; Sjoberg J; Botezatu M; Mulder J; Meulendijks D; Jimeno AT; Zafiropoulos N; Bergh J; Enzmann H; Pignatti F
Letter: ACTA NEUROPATHOLOGICA. 2017;134(4):675-677
A specific antibody to detect transcription factor T-Pit: a reliable marker of corticotroph cell differentiation and a tool to improve the classification of pituitary neuroendocrine tumours
Sjostedt E; Bollerslev J; Mulder J; Lindskog C; Ponten F; Casar-Borota O
Corrigendum: BRAIN STRUCTURE AND FUNCTION. 2016;221(7):3843
Comparative anatomical distribution of neuronal calcium-binding protein (NECAB) 1 and -2 in rodent and human spinal cord (vol 221, pg 3803, 2016)
Zhang M-D; Barde S; Szodorai E; Josephson A; Mitsios N; Watanabe M; Attems J; Lubec G; Kovacs GG; Uhlen M; Mulder J; Harkany T; Hokfelt T
Review: CELLULAR SIGNALLING. 2012;24(2):378-387
The renaissance of Ca²⁺-binding proteins in the nervous system: secretagogin takes center stage
Alpar A; Attems J; Mulder J; Hokfelt T; Harkany T
Published conference paper: EUROPEAN JOURNAL OF NEUROSCIENCE. 2010;31(12):2166-2177
Secretagogin is a Ca2+-binding protein identifying prospective extended amygdala neurons in the developing mammalian telencephalon
Mulder J; Spence L; Tortoriello G; DiNieri JA; Uhlen M; Shui B; Kotlikoff MI; Yanagawa Y; Aujard F; Hokfelt T; Hurd YL; Harkany T
Review: CHEMBIOCHEM. 2009;10(10):1591-1598
The Polarised Life of the Endocannabinoid System in CNS Development
Anavi-Goffer S; Mulder J
Review: JOURNAL OF COMPARATIVE NEUROLOGY. 2009;513(1):1-20
Autoantibodies in Autoimmune Polyglandular Syndrome Type I Patients React with Major Brain Neurotransmitter Systems
Fetissov SO; Bensing S; Mulder J; Le Maitre E; Hulting A-L; Harkany T; Ekwall O; Skoldberg F; Husebye ES; Perheentupa J; Rorsman F; Kaempe O; Hoekfelt T
Published conference paper: MOLECULAR AND CELLULAR ENDOCRINOLOGY. 2008;286(1-2):S84-S90
Endocannabinoid functions controlling neuronal specification during brain development
Harkany T; Keimpema E; Barabas K; Mulder J

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