Jan-Ingmar Flock

Publications
Public outreach and news

Articles

Article: VACCINE. 2018;36(11):1484-1490
Strangvac: A recombinant fusion protein vaccine that protects against strangles, caused by Streptococcus equi
Robinson C; Frykberg L; Flock M; Guss B; Waller AS; Flock J-I
Article: STANDARDS IN GENOMIC SCIENCES. 2013;9(1):1-13
Staphylococcus aureus subsp. anaerobius strain ST1464 genome sequence.
Elbir H; Robert C; Nguyen TT; Gimenez G; El Sanousi SM; Flock J-I; Raoult D; Drancourt M
Article: MUSCLE AND NERVE. 2013;47(2):202-212
Homogenates of skeletal muscle injected with snake venom inhibit myogenic differentiation in cell culture
Saravia-Otten P; Robledo B; Escalante T; Bonilla L; Rucavado A; Lomonte B; Hernandez R; Flock J-I; Maria Gutierrez J; Gastaldello S
Article: APMIS. 2012;120(10):786-793
Protective immunization against Staphylococcus aureus infection in a novel experimental wound model in mice
Schennings T; Farnebo F; Szekely L; Flock J-I
Article: INFECTION AND IMMUNITY. 2012;80(8):2914-2919
Antiphagocytic Function of an IgG Glycosyl Hydrolase from Streptococcus equi subsp equi and Its Use as a Vaccine Component
Flock M; Frykberg L; Skold M; Guss B; Flock J-I
Article: CLINICAL MICROBIOLOGY AND INFECTION (CMI). 2010;16(8):1155-1158
Extracellular adherence protein (Eap) from Staphylococcus aureus does not function as a superantigen
Haggar A; Flock J-I; Norrby-Teglund A
Article: CLINICAL AND VACCINE IMMUNOLOGY. 2010;17(7):1117-1123
Levels of Antibody against 11 Staphylococcus aureus Antigens in a Healthy Population
Colque-Navarro P; Jacobsson G; Andersson R; Flock J-I; Mollby R
Article: JOURNAL OF INFECTION IN DEVELOPING COUNTRIES. 2010;4(4):235-238
Ovine clone ST1464: A predominant genotype of Staphylococcus aureus subsp anaerobius isolated from sheep in Sudan
Elbir H; Feil EJ; Drancourt M; Roux V; El Sanousi SM; Eshag M; Colque-Navarro P; Kuhn I; Flock J-I
Article: PLOS PATHOGENS. 2009;5(9):e1000584
Getting to Grips with Strangles: An Effective Multi-Component Recombinant Vaccine for the Protection of Horses from Streptococcus equi Infection
Guss B; Flock M; Frykberg L; Waller AS; Robinson C; Smith KC; Flock J-I
Article: FEMS MICROBIOLOGY LETTERS. 2009;298(1):44-50
Two novel IgG endopeptidases of Streptococcus equi
Hulting G; Flock M; Frykberg L; Lannergard J; Flock J-I; Guss B
Article: PEDIATRIC RESEARCH. 2009;66(2):174-178
Staphylococcus epidermidis Isolated From Newborn Infants Express Pilus-Like Structures and Are Inhibited by the Cathelicidin-Derived Antimicrobial Peptide LL37
Nelson A; Hultenby K; Hell E; Riedel HM; Brismar H; Flock J-I; Lundahl J; Giske CG; Marchini G
Article: INFECTION AND IMMUNITY. 2008;76(12):5615-5623
More than One Tandem Repeat Domain of the Extracellular Adherence Protein of Staphylococcus aureus Is Required for Aggregation, Adherence, and Host Cell Invasion but Not for Leukocyte Activation
Hussain M; Haggar A; Peters G; Chhatwal GS; Herrmann M; Flock J-I; Sinha B
Article: JOURNAL OF INFECTIOUS DISEASES. 2007;196(5):748-754
Increased infectivity of Staphylococcus aureus in an experimental model of snake venom-induced tissue damage
Saravia-Otten P; Gutierrez JM; Arvidson S; Thelestam M; Flock J-I
Article: VACCINE. 2007;25(18):3629-3635
Vaccination of horses against strangles using recombinant antigens from Streptococcus equi
Waller A; Flock M; Smith K; Robinson C; Mitchell Z; Karlstrom A; Lannergard J; Bergman R; Guss B; Flock J-I
Article: VACCINE. 2006;24(19):4144-4151
Protective effect of vaccination with recombinant proteins from Streptococcus equi subspecies equi in a strangles model in the mouse
Flock M; Karlstrom A; Lannergard J; Guss B; Flock J-I
Article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2006;63(3):184-190
The neutralizing effects of hyperimmune antibodies against extracellular fibrinogen-binding protein, Efb, from Staphylococcus aureus
Shannon O; Uekotter A; Flock JI
Article: INFECTION AND IMMUNITY. 2005;73(11):7243-7251
Studies of fibronectin-binding proteins of Streptococcus equi
Lannergård J; Flock M; Johansson S; Flock JI; Guss B
Article: JOURNAL OF INFECTIOUS DISEASES. 2005;192(2):210-217
Dual effects of extracellular adherence protein from Staphylococcus aureus on peripheral blood mononuclear cells
Haggar A; Shannon O; Norrby-Teglund A; Flock JI
Article: THROMBOSIS AND HAEMOSTASIS. 2005;93(5):927-931
Extracellular fibrinogen binding protein, Efb, from Staphylococcus aureus as an antiplatelet agent in vivo
Shannon O; Uekötter A; Flock JI
Article: SURGICAL ENDOSCOPY. 2005;19(1):91-94
Carbon dioxide inhibits the growth rate of Staphylococcus aureus at body temperature
Persson M; Svenarud P; Flock JI; van der Linden J
Article: VETERINARY MICROBIOLOGY. 2004;104(3-4):179-188
Identification of a novel collagen-like protein, SclC, in Streptococcus equi using signal sequence phage display
Karlström Å; Jacobsson K; Flock M; Flock JI; Guss B
Article: INFECTION AND IMMUNITY. 2004;72(10):6164-6167
The extracellular adherence protein from Staphylococcus aureus inhibits neutrophil binding to endothelial cells
Haggar A; Ehrnfelt C; Holgersson J; Flock JI
Article: INFECTION AND IMMUNITY. 2004;72(6):3228-3236
Recombinant Streptococcus equi proteins protect mice in challenge experiments and induce immune response in horses
Flock M; Jacobsson K; Frykberg L; Hirst TR; Franklin A; Guss B; Flock JI
Article: INFECTION AND IMMUNITY. 2004;72(5):3081-3083
Fibrinogen binding protein of Staphylococcus epidermidis is a target for opsonic antibodies
Rennermalm A; Nilsson M; Flock JI
Article: THROMBOSIS AND HAEMOSTASIS. 2004;91(4):779-789
Extracellular fibrinogen binding protein, Efb, from Staphylococcus aureus binds to platelets and inhibits platelet aggregation
Shannon O; Flock JI
Article: JOURNAL OF HOSPITAL INFECTION. 2003;54(4):294-299
Antiseptic wound ventilation with a gas diffuser: a new intraoperative method to prevent surgical wound infection?
Persson M; Flock JI; van der Linden J
Article: INFECTION AND IMMUNITY. 2003;71(5):2310-2317
Extracellular adherence protein from Staphylococcus aureus enhances internalization into eukaryotic cells
Haggar A; Hussain M; Lönnies H; Herrmann M; Norrby-Teglund A; Flock JI
Article: PROTEIN AND PEPTIDE LETTERS. 2002;9(6):533-543
Antibiotic properties of novel synthetic temporin A analogs and a cecropin A-temporin a hybrid peptide
Wade D; Flock JI; Edlund C; Löfving-Arvholm I; Sallberg M; Bergman T; Silveira A; Unson C; Rollins-Smith L; Silberring J; Richardson M; Kuusela P; Lankinen H
Article: NATURE MEDICINE. 2002;8(7):687-693
Staphylococcus aureus extracellular adherence protein serves as anti-inflammatory factor by inhibiting the recruitment of host leukocytes
Chavakis T; Hussain M; Kanse SM; Peters G; Bretzel RG; Flock JI; Herrmann M; Preissner KT
Article: MICROBIOLOGY (UNITED KINGDOM). 2002;148(Pt 7):2037-2044
A novel von Willebrand factor binding protein expressed by Staphylococcus aureus
Bjerketorp J; Nilsson M; Ljungh Å; Flock JI; Jacobsson K; Frykberg L
Article: INFECTION AND IMMUNITY. 2002;70(6):2933-2940
Insertional inactivation of eap in Staphylococcus aureus strain Newman confers reduced staphylococcal binding to fibroblasts
Hussain M; Haggar A; Heilmann C; Peters G; Flock JI; Herrmann M
Article: MICROBIAL PATHOGENESIS. 2001;31(4):185-193
Lack of fbe, the gene for a fibrinogen-binding protein from Staphylococcus epidermidis, reduces its adherence to fibrinogen coated surfaces
Pei L; Flock JI
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2001;276(34):31691-31697
Extracellular fibrinogen-binding protein, Efb, from Staphylococcus aureus blocks platelet aggregation due to its binding to the α-chain
Palma M; Shannon O; Quezada HC; Berg A; Flock JI
Article: JOURNAL OF INFECTIOUS DISEASES. 2001;184(1):52-55
Functional study of antibodies against a fibrogenin-binding protein in Staphylococcus epidermidis adherence to polyethylene catheters
Pei L; Flock JI
Article: JOURNAL OF BACTERIOLOGY. 2001;183(13):3999-4003
Rebinding of extracellular adherence protein Eap to Staphylococcus aureus can occur through a surface-bound neutral phosphatase
Flock M; Flock JI
Article: VACCINE. 2001;19(25-26):3376-3383
Antibodies against a truncated Staphylococcus aureus fibronectin-binding protein protect against dissemination of infection in the rat
Rennermalm A; Li YH; Bohaufs L; Jarstrand C; Brauner A; Brennan FR; Flock JI
Article: CLINICAL ORTHOPAEDICS AND RELATED RESEARCH. 2001;(382):241-246
Collagen and fibronectin binding in experimental staphylococcal osteomyelitis
Johansson Å; Flock JI; Svensson O
Article: CLINICAL AND VACCINE IMMUNOLOGY. 2000;7(1):14-20
Antibody responses in patients with staphylococcal septicemia against two Staphylococcus aureus fibrinogen binding proteins:: Clumping factor and an extracellular fibrinogen binding protein
Colque-Navarro P; Palma M; Söderquist B; Flock JI; Möllby R
Article: INFECTION AND IMMUNITY. 1999;67(9):4525-4530
Functional studies of a fibrinogen binding protein from Staphylococcus epidermidis
Pei L; Palma M; Nilsson M; Guss B; Flock JI
Article: JOURNAL OF BACTERIOLOGY. 1999;181(9):2840-2845
Adherence of Staphylococcus aureus is enhanced by an endogenous secreted protein with broad binding activity
Palma M; Haggar A; Flock JI
Article: VACCINE. 1999;17(15-16):1846-1857
Immunogenicity of peptides derived from a fibronectin-binding protein of S-aureus expressed on two different plant viruses
Brennan FR; Jones TD; Longstaff M; Chapman S; Bellaby T; Smith H; Xu F; Hamilton WDO; Flock JI
Article: JOURNAL OF VIROLOGY. 1999;73(2):930-938
Chimeric plant virus particles administered nasally or orally induce systemic and mucosal immune responses in mice.
Brennan FR; Bellaby T; Helliwell SM; Jones TD; Kamstrup S; Dalsgaard K; Flock JI; Hamilton WD
Article: AIDS. 1998;12(15):1973-1981
Coexisting members of HIV-1 p17 gene quasispecies represent proteins with distinct antigenicity and immunogenicity
Birk M; Flock JI; Sönnerborg A; Sallberg M
Article: INFECTION AND IMMUNITY. 1998;66(6):2666-2673
A fibrinogen-binding protein of Staphylococcus epidermidis
Nilsson M; Frykberg L; Flock JI; Pei L; Lindberg M; Guss B
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 1998;273(21):13177-13181
Multiple binding sites in the interaction between an extracellular fibrinogen-binding protein from Staphylococcus aureus and fibrinogen
Palma M; Wade D; Flock M; Flock JI
Article: CLINICAL MICROBIOLOGY AND INFECTION (CMI). 1998;4(4):181-185
Antianaerobic activity of a cecropin---melittin peptide.
Edlund C; Hedberg M; Engström A; Flock J-I; Wade D
Article: FEMS IMMUNOLOGY AND MEDICAL MICROBIOLOGY. 1997;19(3):247-253
Fibronectin binding by Propionibacterium acnes
Yu JL; Mansson R; Flock JI; Ljungh A
Article: INFECTION AND IMMUNITY. 1996;64(12):5284-5289
Lack of the extracellular 19-kilodalton fibrinogen-binding protein from Staphylococcus aureus decreases virulence in experimental wound infection
Palma M; Nozohoor S; Schennings T; Heimdahl A; Flock JI
Article: ARCHIVES OF ORAL BIOLOGY. 1996;41(10):999-1002
Streptococcus mutans major adhesion surface protein, P1 (I/II), does not contribute to attachment to valvular vegetations or to the development of endocarditis in a rat model
Ryd M; Schennings T; Flock M; Heimdahl A; Flock JI
Article: JOURNAL OF BACTERIOLOGY. 1996;178(17):5327-5329
Insertional inactivation of the gene for collagen-binding protein has a pleiotropic effect on the phenotype of Staphylococcus aureus
Hienz SA; Palma M; Flock JI
Article: JOURNAL OF INFECTIOUS DISEASES. 1996;174(1):83-88
Collagen binding of Staphylococcus aureus is a virulence factor in experimental endocarditis
Hienz SA; Schennings T; Heimdahl A; Flock JI
Article: INFECTION AND IMMUNITY. 1996;64(5):1876-1878
Reconsideration of the role of fibronectin binding in endocarditis caused by Staphylococcus aureus
Flock JI; Hienz SA; Heimdahl A; Schennings T
Article: JOURNAL OF CLINICAL MICROBIOLOGY. 1995;33(9):2347-2352
INCIDENCE OF THE HIGHLY CONSERVED FIB GENE AND EXPRESSION OF THE FIBRINOGEN-BINDING (FIB) PROTEIN AMONG CLINICAL ISOLATES OF STAPHYLOCOCCUS-AUREUS
WASTFELT MKB; FLOCK JI
Article: APMIS. 1995;103(9):679-685
TYPING OF COAGULASE-NEGATIVE STAPHYLOCOCCI FROM PERITONITIS IN CAPD PATIENTS BY THE PHP-CS SYSTEM AND REA
JUNG K; BRAUNER A; KUHN I; RANSJO U; HYLANDER B; FLOCK JI; MOLLBY R
Article: BIOCHIMICA ET BIOPHYSICA ACTA: INTERNATIONAL JOURNAL OF BIOCHEMISTRY AND BIOPHYSICS. 1995;1250(1):110-116
Isolation and characterisation of a vitronectin-binding surface protein from Staphylococcus aureus.
Liang OD; Flock JI; Wadström T
Article: JOURNAL OF INFECTIOUS DISEASES. 1995;171(5):1230-1236
DEVELOPMENT AND CHARACTERIZATION OF A NEW MODEL OF HEMATOGENOUS OSTEOMYELITIS IN THE RAT
HIENZ SA; SAKAMOTO H; FLOCK JI; MORNER AC; REINHOLT FP; HEIMDAHL A; NORD CE
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Review: MICROBIOLOGY (UNITED KINGDOM). 2003;149(Pt 10):2701-2707
The adhesive and immunomodulating properties of the multifunctional Staphylococcus aureus protein Eap
Harraghy N; Hussain M; Haggar A; Chavakis T; Sinha B; Herrmann M; Flock JI
Published conference paper: JOURNAL OF CHROMATOGRAPHY B: ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES. 2003;786(1-2):319-325
GST-Fbe can recognize β-chains of fibrin(ogen) on explanted materials
Pei L; Arvholm IL; Lonnies L; Flock JI
Review: TRENDS IN MOLECULAR MEDICINE. 1999;5(12):532-537
Extracellular-matrix-binding proteins as targets for the prevention of Staphylococcus aureus infections
Flock JI
Letter: TRENDS IN MICROBIOLOGY. 1999;7(4):140-141
Antibodies that block adherence of Staphylococcus aureus to fibronectin
Flock JI; Brennan F
Published conference paper: PROTEIN AND PEPTIDE LETTERS. 1998;5(4):199-206
Structural analysis of Efb, a fibrinogen binding protein of Staphylococcus aureus
Wade D; Palma M; Flock JI; Berndt KD; Silberring J; Galaktionov SG
Published conference paper: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 1998;248(3):690-695
Identification of functional domains in Efb, a fibrinogen binding protein of Staphylococcus aureus
Wade D; Palma M; Löfving-Arvholm I; Sällberg M; Silberring J; F'lock JI
Published conference paper: JOURNAL OF INFECTIOUS DISEASES. 1997;176(4):1096-1099
Expression of collagen-binding protein and types 5 and 8 capsular polysaccharide in clinical isolates of Staphylococcus aureus
Ryding U; Flock JI; Flock M; Soderquist B; Christensson B

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