Isabelle Laine

Articles

Article: NATURE COMMUNICATIONS. 2022;13(1):5750
ANGEL2 phosphatase activity is required for non-canonical mitochondrial RNA processing
Clemente P; Calvo-Garrido J; Pearce SF; Schober FA; Shigematsu M; Siira SJ; Laine I; Spahr H; Steinmetzger C; Petzold K; Kirino Y; Wibom R; Rackham O; Filipovska A; Rorbach J; Freyer C; Wredenberg A
Article: PLOS GENETICS. 2019;15(7):e1008240
Defects of mitochondrial RNA turnover lead to the accumulation of double-stranded RNA in vivo
Pajak A; Laine I; Clemente P; El-Fissi N; Schober FA; Maffezzini C; Calvo-Garrido J; Wibom R; Filograna R; Dhir A; Wedell A; Freyer C; Wredenberg A
Article: MOLECULAR GENETICS & GENOMIC MEDICINE. 2019;7(6):e654
Mutations in the mitochondrial tryptophanyl-tRNA synthetase cause growth retardation and progressive leukoencephalopathy
Maffezzini C; Laine I; Dallabona C; Clemente P; Calvo-Garrido J; Wibom R; Naess K; Barbaro M; Falk A; Donnini C; Freyer C; Wredenberg A; Wedell A
Article: NUCLEIC ACIDS RESEARCH (NAR). 2015;43(15):7398-7413
SUV3 helicase is required for correct processing of mitochondrial transcripts
Clemente P; Pajak A; Laine I; Wibom R; Wedell A; Freyer C; Wredenberg A

Affiliated to Research, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, 2023-2025
Clinical Assistant, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, 2023-2024

Degree Of Doctor Of Philosophy, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, 2022
Degree Of Master Of Science In Medicine, Karolinska Institutet, 2021
Degree of Master, Molecular Life Sciences, Stockholm University, 2014